Items where Faculty or Department is "Department of Infection Biology"
LSHTM Organisational Structure (57264)
Faculty of Infectious and Tropical Diseases (18516)
Department of Infection Biology (5552)
Dept of Immunology and Infection (-2019) (972)
Dept of Pathogen Molecular Biology (-2019) (1192)
Number of items: 99.
September 2003
Suramin and suramin analogues inhibit merozoite surface protein-1 secondary processing and erythrocyte invasion by the malaria parasite Plasmodium falciparum. (2003)
Fleck, Suzanne L; Birdsall, Berry; Babon, Jeffrey; Dluzewski, Anton R; Martin, Stephen R; Morgan, William D; Angov, Evelina; Kettleborough, Catherine A; Feeney, James; Blackman, Michael J; Holder, Anthony A
2003
Entamoeba moshkovskii infections in children, Bangladesh. (2003)
Ali, Ibne Karim M; Hossain, Mohammad Bakhtiar; Roy, Shantanu; Ayeh-Kumi, Patrick F; Petri, William A; Haque, Rashidul; Clark, C Graham
Genes to genetic immunization: identification of bacterial vaccine candidates. (2003)
Allan, Elaine; Wren, Brendan W
Protective efficacy of the RTS,S/AS02 Plasmodium falciparum malaria vaccine is not strain specific. (2003)
Alloueche, Ali; Milligan, Paul; Conway, David J; Pinder, Margaret; Bojang, Kalifa; Doherty, Tom; Tornieporth, Nadia; Cohen, Joe; Greenwood, Brian M
The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei. (2003)
Alsford, NS; Navarro, M; Jamnadass, HR; Dunbar, H; Ackroyd, M; Murphy, NB; Gull, K; Ersfeld, K
Analysis of genes of mitochondrial origin in the genus Entamoeba. (2003)
Bakatselou, Christina; Beste, Dany; Kadri, Ayodeji O; Somanath, Sushela; Clark, C Graham
Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity. (2003)
Bal, Gunther; Van der Veken, Pieter; Antonov, Dimitri; Lambeir, Anne-Marie; Grellier, Philippe; Croft, Simon L; Augustyns, Koen; Haemers, Achiel
Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development. (2003)
Bannister, Lawrence H; Hopkins, John M; Dluzewski, Anton R; Margos, Gabriele; Williams, Ian T; Blackman, Michael J; Kocken, Clemens H; Thomas, Alan W; Mitchell, Graham H
Erythrocyte invasion phenotypes of Plasmodium falciparum in The Gambia. (2003)
Baum, Jake; Pinder, Margaret; Conway, David J
Evidence for diversifying selection on erythrocyte-binding antigens of Plasmodium falciparum and P. vivax. (2003)
Baum, Jake; Thomas, Alan W; Conway, David J
Gamma interferon responses induced by a panel of recombinant and purified mycobacterial antigens in healthy, non-mycobacterium bovis BCG-vaccinated Malawian young adults. (2003)
Black, Gillian F; Weir, Rosemary E; Chaguluka, Steven D; Warndorff, David; Crampin, Amelia C; Mwaungulu, Lorren; Sichali, Lifted; Floyd, Sian; Bliss, Lyn; Jarman, Elizabeth; Donovan, Linda; Andersen, Peter; Britton, Warwick; Hewinson, Glyn; Huygen, Kris; Paulsen, Jens; Singh, Mahavir; Prestidge, Ross; Fine, Paul EM; Dockrell, Hazel M
RNAi in protozoan parasites: what hope for the Apicomplexa? (2003)
Blackman, Michael J
Longitudinal study of intestinal Entamoeba histolytica infections in asymptomatic adult carriers. (2003)
Blessmann, Joerg; Ali, Ibne Karim M; Nu, Phuong A Ton; Dinh, Binh T; Viet, Tram Q Ngo; Van, An Le; Clark, C Graham; Tannich, Egbert
Survival analysis Part III: multivariate data analysis -- choosing a model and assessing its adequacy and fit. (2003)
Bradburn, MJ; Clark, TG; Love, SB; Altman, DG
Survival analysis part II: multivariate data analysis--an introduction to concepts and methods. (2003)
Bradburn, MJ; Clark, TG; Love, SB; Altman, DG
Missing... presumed at random: cost-analysis of incomplete data. (2003)
Briggs, Andrew; Clark, Taane; Wolstenholme, Jane; Clarke, Philip
Screening of plant extracts for antiprotozoal and cytotoxic activities. (2003)
Camacho, MDR; Phillipson, JD; Croft, SL; Solis, PN; Marshall, SJ; Ghazanfar, SA
Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. (2003)
Chauvière, Gérard; Bouteille, Bernard; Enanga, Bertin; de Albuquerque, Cristina; Croft, Simon L; Dumas, Michel; Périé, Jacques
Survival analysis part I: basic concepts and first analyses. (2003)
Clark, TG; Bradburn, MJ; Love, SB; Altman, DG
Survival analysis part IV: further concepts and methods in survival analysis. (2003)
Clark, TG; Bradburn, MJ; Love, SB; Altman, DG
Long term risks of stroke, myocardial infarction, and vascular death in "low risk" patients with a non-recent transient ischaemic attack. (2003)
Clark, TG; Murphy, MFG; Rothwell, PM
Developing a prognostic model in the presence of missing data: an ovarian cancer case study. (2003)
Clark, Taane G; Altman, Douglas G
Tracing the dawn of Plasmodium falciparum with mitochondrial genome sequences. (2003)
Conway, David J
Recent advances in research and control of malaria, leishmaniasis, trypanosomiasis and schistosomiasis. (2003)
Croft, SL; Vivas, L; Brooker, S
Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs. (2003)
Croft, Simon L; Coombs, Graham H
Antiprotozoal activities of phospholipid analogues. (2003)
Croft, Simon L; Seifert, Karin; Duchêne, Michael
Leishmaniasis: new approaches to disease control. (2003)
Davies, Clive R; Kaye, Paul; Croft, Simon L; Sundar, Shyam
The role of two novel regulatory sites in the activation of the cGMP-dependent protein kinase from Plasmodium falciparum. (2003)
Deng, Wensheng; Parbhu-Patel, Asha; Meyer, David J; Baker, David A
SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development. (2003)
Dessens, Johannes T; Sidén-Kiamos, Inga; Mendoza, Jacqui; Mahairaki, Vassiliki; Khater, Emad; Vlachou, Dina; Xu, Xiao-Jin; Kafatos, Fotis C; Louis, Christos; Dimopoulos, George; Sinden, Robert E
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. (2003)
Diebold, Sandra S; Montoya, Maria; Unger, Hermann; Alexopoulou, Lena; Roy, Polly; Haswell, Linsey E; Al-Shamkhani, Aymen; Flavell, Richard; Borrow, Persephone; Reis e Sousa, Caetano
An estimation of the entomological inoculation rate for Ifakara: a semi-urban area in a region of intense malaria transmission in Tanzania. (2003)
Drakeley, C; Schellenberg, D; Kihonda, J; Sousa, CA; Arez, AP; Lopes, D; Lines, J; Mshinda, H; Lengeler, C; Armstrong Schellenberg, J; Tanner, M; Alonso, P
Widespread occurrence of Mycobacterium tuberculosis DNA from 18th-19th century Hungarians. (2003)
Fletcher, Helen A; Donoghue, Helen D; Holton, John; Pap, Ildikó; Spigelman, Mark
Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians. (2003)
Fletcher, Helen A; Donoghue, Helen D; Taylor, G Michael; van der Zanden, Adri GM; Spigelman, Mark
Genetic diversity and antigenic polymorphism in Plasmodium falciparum: extensive serological cross-reactivity between allelic variants of merozoite surface protein 2. (2003)
Franks, Simon; Baton, Luke; Tetteh, Kevin; Tongren, Eric; Dewin, David; Akanmori, Bartholomew D; Koram, Kojo A; Ranford-Cartwright, Lisa; Riley, Eleanor M
Mechanism of genetic exchange in American trypanosomes. (2003)
Gaunt, Michael W; Yeo, Matthew; Frame, Iain A; Stothard, J Russell; Carrasco, Hernan J; Taylor, Martin C; Mena, Susana Solis; Veazey, Paul; Miles, Graham AJ; Acosta, Nidia; de Arias, Antonieta Rojas; Miles, Michael A
Synthesis and characterization of copper(II) complexes of pyridine-2-carboxamidrazones as potent antimalarial agents. (2003)
Gokhale, Nikhil H; Padhye, Subhash B; Billington, David C; Rathbone, Daniel L; Croft, Simon L; Kendrick, Howard D; Anson, Christopher E; Powell, Annie K
Transition metal complexes of buparvaquone as potent new antimalarial agents. 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum. (2003)
Gokhale, Nikhil H; Padhye, Subhash B; Croft, Simon L; Kendrick, Howard D; Davies, Wendy; Anson, Christopher E; Powell, Annie K
Early self-regulatory mechanisms control the magnitude of CD8+ T cell responses against liver stages of murine malaria. (2003)
Hafalla, Julius CR; Morrot, Alexandre; Sano, Gen-Ichiro; Milon, Geneviève; Lafaille, Juan J; Zavala, Fidel
Contrasting roles for IL-10 in protective immunity to different life cycle stages of intestinal nematode parasites. (2003)
Helmby, Helena; Grencis, Richard K
Essential role for TLR4 and MyD88 in the development of chronic intestinal nematode infection. (2003)
Helmby, Helena; Grencis, Richard K
IFN-gamma-independent effects of IL-12 during intestinal nematode infection. (2003)
Helmby, Helena; Grencis, Richard K
Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis. (2003)
Hinchliffe, Stewart J; Isherwood, Karen E; Stabler, Richard A; Prentice, Michael B; Rakin, Alexander; Nichols, Richard A; Oyston, Petra CF; Hinds, Jason; Titball, Richard W; Wren, Brendan W
Functional characterization of the propeptide of Plasmodium falciparum subtilisin-like protease-1. (2003)
Jean, Letitia; Hackett, Fiona; Martin, Stephen R; Blackman, Michael J
Dynamics of cytokine generation in patients with active pulmonary tuberculosis. (2003)
Jo, Eun-Kyeong; Park, Jeong-Kyu; Dockrell, Hazel M
A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface. (2003)
Joshua, GWP; Karlyshev, AV; Smith, MP; Isherwood, KE; Titball, RW; Wren, BW
Defining the structure-function relationships of bluetongue virus helicase protein VP6. (2003)
Kar, Alak Kanti; Roy, Polly
Natural products as antiparasitic drugs. (2003)
Kayser, O; Kiderlen, AF; Croft, SL
Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs. (2003)
Kayser, O; Olbrich, C; Croft, SL; Kiderlen, AF
Formulation of amphotericin B as nanosuspension for oral administration. (2003)
Kayser, O; Olbrich, C; Yardley, V; Kiderlen, AF; Croft, SL
Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae). (2003)
Kayser, Oliver; Kiderlen, Albrecht F; Croft, Simon L
Toxicity and antileishmanial activity of a new stable lipid suspension of amphotericin B. (2003)
Larabi, Malika; Yardley, Vanessa; Loiseau, Philippe M; Appel, Martine; Legrand, Philippe; Gulik, Annette; Bories, Christian; Croft, Simon L; Barratt, Gillian
New World cutaneous leishmaniasis in returned travellers: treatment failures using intravenous sodium stibogluconate. (2003)
Lawn, SD; Yardley, V; Vega-Lopez, F; Watson, J; Lockwood, DN
The production of tumour necrosis factor-alpha is decreased in peripheral blood mononuclear cells from multidrug-resistant tuberculosis patients following stimulation with the 30-kDa antigen of Mycobacterium tuberculosis. (2003)
Lee, J-S; Song, C-H; Lim, J-H; Kim, H-J; Park, J-K; Paik, T-H; Kim, C-H; Kong, S-J; Shon, M-H; Jung, S-S; Jo, E-K
Monocyte chemotactic protein-1 production in patients with active pulmonary tuberculosis and tuberculous pleurisy. (2003)
Lee, J-S; Song, C-H; Lim, J-H; Lee, K-S; Kim, H-J; Park, J-K; Paik, T-H; Jung, S-S; Jo, E-K
Depressed interleukin-12 production by peripheral blood mononuclear cells after in vitro stimulation with the 30-kDa antigen in recurrent pulmonary tuberculosis patients. (2003)
Lee, Ji-Sook; Song, Chang-Hwa; Kim, Chul-Hee; Kong, Suck-Jun; Shon, Mal-Hyun; Suhr, Ji-Won; Jung, Sung-Soo; Lim, Jae-Hyun; Kim, Hwa-Jung; Park, Jeong-Kyu; Paik, Tae-Hyun; Jo, Eun-Kyeong
Intermolecular interactions in a two-layered viral capsid that requires a complex symmetry mismatch. (2003)
Limn, Chang-Kwang; Roy, Polly
Structure-activity relationships of antileishmanial and antimalarial chalcones. (2003)
Liu, Mei; Wilairat, Prapon; Croft, Simon L; Tan, Agnes Lay-Choo; Go, Mei-Lin
Sequence specificity in the interaction of Bluetongue virus non-structural protein 2 (NS2) with viral RNA. (2003)
Lymperopoulos, Kostas; Wirblich, Christoph; Brierley, Ian; Roy, Polly
Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi. (2003)
Magaraci, Filippo; Jimenez, Carmen Jimenez; Rodrigues, Carlos; Rodrigues, Juliany CF; Braga, Marina Vianna; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; de Souza, Wanderley; Ruiz-Perez, Luis M; Urbina, Julio; Gonzalez Pacanowska, Dolores; Gilbert, Ian H
Using a DNA microarray to investigate the distribution of insect virulence factors in strains of photorhabdus bacteria. (2003)
Marokhazi, Judit; Waterfield, Nicholas; LeGoff, Gaelle; Feil, Edward; Stabler, Richard; Hinds, Jason; Fodor, Andras; ffrench-Constant, Richard H
Serum IgG3 to the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malaria. (2003)
Metzger, Wolfram G; Okenu, Daniel MN; Cavanagh, David R; Robinson, Jane V; Bojang, Kalifa A; Weiss, Helen A; McBride, Jana S; Greenwood, Brian M; Conway, David J
Malaria--there could be a third way. (2003)
Miles, Michael A
American trypanosomiasis (Chagas' disease) and the role of molecular epidemiology in guiding control strategies. (2003)
Miles, Michael A; Feliciangeli, M Dora; de Arias, Antonieta Rojas
TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase. (2003)
Miller, Steven A; Thathy, Vandana; Ajioka, James W; Blackman, Michael J; Kim, Kami
Multiple splice variants encode a novel adenylyl cyclase of possible plastid origin expressed in the sexual stage of the malaria parasite Plasmodium falciparum. (2003)
Muhia, David K; Swales, Claire A; Eckstein-Ludwig, Ursula; Saran, Shweta; Polley, Spencer D; Kelly, John M; Schaap, Pauline; Krishna, Sanjeev; Baker, David A
Genetic polymorphisms and personality in healthy adults: a systematic review and meta-analysis. (2003)
Munafò, MR; Clark, TG; Moore, LR; Payne, E; Walton, R; Flint, J
Virus-like particles as immunogens. (2003)
Noad, Rob; Roy, Polly
Signature-tagged mutagenesis of Yersinia pestis. (2003)
Oyston, Petra CF; Karlyshev, Andrey V; Wren, Brendan W; Titball, Richard W
Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis. (2003)
Parish, Tanya; Smith, Debbie A; Kendall, Sharon; Casali, Nicola; Bancroft, Gregory J; Stoker, Neil G
Expression profile of wild-type ETV6 in childhood acute leukaemia. (2003)
Patel, Naina; Goff, Lindsey K; Clark, Taane; Ford, Anthony M; Foot, Nicola; Lillington, Debra; Hing, Sandra; Pritchard-Jones, Kathy; Jones, Louise K; Saha, Vaskar
Molecular determination of point mutation haplotypes in the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum in three districts of northern Tanzania. (2003)
Pearce, Richard J; Drakeley, Chris; Chandramohan, Daniel; Mosha, Frank; Roper, Cally
The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines. (2003)
Peters, W; Stewart, LB; Robinson, BL
2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase. (2003)
Pez, Didier; Leal, Isabel; Zuccotto, Fabio; Boussard, Cyrille; Brun, Reto; Croft, Simon L; Yardley, Vanessa; Ruiz Perez, Luis M; Gonzalez Pacanowska, Dolores; Gilbert, Ian H
Allele frequency-based analyses robustly map sequence sites under balancing selection in a malaria vaccine candidate antigen. (2003)
Polley, Spencer D; Chokejindachai, Watcharee; Conway, David J
Repeat sequences in block 2 of Plasmodium falciparum merozoite surface protein 1 are targets of antibodies associated with protection from malaria. (2003)
Polley, Spencer D; Tetteh, Kevin KA; Cavanagh, David R; Pearce, Richard J; Lloyd, Jennifer M; Bojang, Kalifa A; Okenu, Daniel MN; Greenwood, Brian M; McBride, Jana S; Conway, David J
Cobalamin synthesis in Yersinia enterocolitica 8081. Functional aspects of a putative metabolic island. (2003)
Prentice, Michael B; Cuccui, Jon; Thomson, Nick; Parkhill, Julian; Deery, Evelyn; Warren, Martin J
Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira. (2003)
Ramírez, Irama; Carabot, Alfredo; Meléndez, Pablo; Carmona, Juan; Jimenez, Manuel; Patel, Asmita V; Crabb, Trevor A; Blunden, Gerald; Cary, Peter D; Croft, Simon L; Costa, Manuel
Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. (2003)
Ren, Hongyu; Grady, Shannon; Banghart, Matthew; Moulthrop, Jason S; Kendrick, Howard; Yardley, Vanessa; Croft, Simon L; Moyna, Guillermo
Antifolate antimalarial resistance in southeast Africa: a population-based analysis. (2003)
Roper, Cally; Pearce, Richard; Bredenkamp, Barry; Gumede, Jonathan; Drakeley, Chris; Mosha, Frank; Chandramohan, Daniel; Sharp, Brian
Nature and duration of protective immunity to bluetongue virus infection. (2003)
Roy, P
Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). (2003)
Seifert, Karin; Matu, Sangeeta; Javier Pérez-Victoria, F; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L
Interleukin-8 is differentially expressed by human-derived monocytic cell line U937 infected with Mycobacterium tuberculosis H37Rv and Mycobacterium marinum. (2003)
Song, Chang-Hwa; Lee, Ji-Sook; Kim, Hwa-Jung; Park, Jeong-Kyu; Paik, Tae-Hyun; Jo, Eun-Kyeong
Role of mitogen-activated protein kinase pathways in the production of tumor necrosis factor-alpha, interleukin-10, and monocyte chemotactic protein-1 by Mycobacterium tuberculosis H37Rv-infected human monocytes. (2003)
Song, Chang-Hwa; Lee, Ji-Sook; Lee, So-Hyun; Lim, Kyu; Kim, Hwa-Jung; Park, Jeong-Kyu; Paik, Tae-Hyun; Jo, Eun-Kyeong
Construction of a Yersinia pestis microarray. (2003)
Stabler, Richard A; Hinds, Jason; Witney, Adam A; Isherwood, Karen; Oyston, Petra; Titball, Richard; Wren, Brendan; Hinchliffe, Stewart; Prentice, Michael; Mangan, Joseph A; Butcher, Phillip D
The addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children delays, but does not prevent treatment failure. (2003)
Sutherland, Colin J; Drakeley, Christopher J; Obisike, Uche; Coleman, Rosalind; Jawara, Musa; Targett, Geoffrey AT; Milligan, Paul; Pinder, Margaret; Walraven, Gijs
Campylobacter--a tale of two protein glycosylation systems. (2003)
Szymanski, Christine M; Logan, Susan M; Linton, Dennis; Wren, Brendan W
Sympatric Plasmodium falciparum isolates from Venezuela have structured var gene repertoires. (2003)
Tami, Adriana; Ord, Rosalynn; Targett, Geoffrey AT; Sutherland, Colin J
Gene discovery in the Entamoeba invadens genome. (2003)
Wang, Zheng; Samuelson, John; Clark, C Graham; Eichinger, Daniel; Paul, Jaishree; Van Dellen, Katrina; Hall, Neil; Anderson, Iain; Loftus, Brendan
Interferon-gamma and skin test responses of schoolchildren in southeast England to purified protein derivatives from Mycobacterium tuberculosis and other species of mycobacteria. (2003)
Weir, RE; Fine, PEM; Nazareth, B; Floyd, S; Black, GF; King, E; Stanley, C; Bliss, L; Branson, K; Dockrell, HM
Motor vehicle driver injury and socioeconomic status: a cohort study with prospective and retrospective driver injuries. (2003)
Whitlock, G; Norton, R; Clark, T; Pledger, M; Jackson, R; MacMahon, S
Is body mass index a risk factor for motor vehicle driver injury? A cohort study with prospective and retrospective outcomes. (2003)
Whitlock, Gary; Norton, Robyn; Clark, Taane; Jackson, Rodney; MacMahon, Stephen
RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome. (2003)
Wilkinson, Shane R; Horn, David; Prathalingam, S Radhika; Kelly, John M
The role of glutathione peroxidases in trypanosomatids. (2003)
Wilkinson, Shane R; Kelly, John M
The yersiniae--a model genus to study the rapid evolution of bacterial pathogens. (2003)
Wren, Brendan W
Genotyping of Entamoeba species in South Africa: diversity, stability, and transmission patterns within families. (2003)
Zaki, Mehreen; Reddy, Selvan G; Jackson, Terry FHG; Ravdin, Jonathan I; Clark, C Graham
Entamoeba histolytica: direct PCR-based typing of strains using faecal DNA. (2003)
Zaki, Mehreen; Verweij, Jaco J; Clark, C Graham
The effect of mass administration of sulfadoxine-pyrimethamine combined with artesunate on malaria incidence: a double-blind, community-randomized, placebo-controlled trial in The Gambia. (2003)
von Seidlein, Lorenz; Walraven, Gijs; Milligan, Paul J; Alexander, Neal; Manneh, Fandingding; Deen, Jacqueline L; Coleman, Roz; Jawara, Musa; Lindsay, Steve W; Drakeley, Chris; De Martin, Sarah; Olliaro, Piero; Bennett, Steve; Schim van der Loeff, Maarten; Okunoye, Kunle; Targett, Geoff A; McAdam, Keith P; Doherty, Justin F; Greenwood, Brian M; Pinder, Margaret