Items where Faculty or Department is "Department of Infection Biology"
LSHTM Organisational Structure (57264)
Faculty of Infectious and Tropical Diseases (18516)
Department of Infection Biology (5552)
Dept of Immunology and Infection (-2019) (972)
Dept of Pathogen Molecular Biology (-2019) (1192)
Number of items: 91.
Article
Frequent and persistent, asymptomatic Plasmodium falciparum infections in African infants, characterized by multilocus genotyping. (2001)
Franks, S; Koram, KA; Wagner, GE; Tetteh, K; McGuinness, D; Wheeler, JG; Nkrumah, F; Ranford-Cartwright, L; Riley, EM
Biogeography of Triatominae (Hemiptera: Reduviidae) in Ecuador: implications for the design of control strategies. (2001)
Abad-Franch, F; Paucar, A; Carpio, C; Cuba, CA; Aguilar, HM; Miles, MA
Antiplasmodial activities of some Ghanaian plants traditionally used for fever/malaria treatment and of some alkaloids isolated from Pleiocarpa mutica; in vivo antimalarial activity of pleiocarpine. (2001)
Addae-Kyereme, J; Croft, SL; Kendrick, H; Wright, CW
Characterization of the low-pH responses of Helicobacter pylori using genomic DNA arrays. (2001)
Allan, Elaine; Clayton, Christopher L; McLaren, Alistair; Wallace, Donald M; Wren, Brendan W
Trypanosoma cruzi: mucin pseudogenes organized in a tandem array. (2001)
Allen, CL; Kelly, JM
Diversity and dynamics of the minichromosomal karyotype in Trypanosoma brucei. (2001)
Alsford, S; Wickstead, B; Ersfeld, K; Gull, K
Plight of Afghan people must not be forgotten. (2001)
Armstrong, B; Coleman, M; Davies, C; Elbourne, D; Fletcher, A; Grundy, E; Haines, A; Hall, A; Kirkwood, B; Lamping, D; Miles, M; Roberts, I; Sondorp, E
In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle. (2001)
Asres, K; Bucar, F; Knauder, E; Yardley, V; Kendrick, H; Croft, SL
Transformation of Leishmania mexicana metacyclic promastigotes to amastigote-like forms mediated by binding of human C-reactive protein. (2001)
Bee, A; Culley, FJ; Alkhalife, IS; Bodman-Smith, KB; Raynes, JG; Bates, PA
Population genetic analysis of the Plasmodium falciparum erythrocyte binding antigen-175 (eba-175) gene. (2001)
Binks, RH; Baum, J; Oduola, AM; Arnot, DE; Babiker, HA; Kremsner, PG; Roper, C; Greenwood, BM; Conway, DJ
Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern Malawi. (2001)
Black, GF; Dockrell, HM; Crampin, AC; Floyd, S; Weir, RE; Bliss, L; Sichali, L; Mwaungulu, L; Kanyongoloka, H; Ngwira, B; Warndorff, DK; Fine, PE
Relationship between IFN-gamma and skin test responsiveness to Mycobacterium tuberculosis PPD in healthy, non-BCG-vaccinated young adults in Northern Malawi. (2001)
Black, GF; Fine PEM; Warndorff, DK; Floyd, S; Weir, RE; Blackwell, JM; Bliss, L; Sichali, L; Mwaungulu, L; Chaguluka, S; Jarman, E; Ngwira, B; Dockrell, HM
Apical organelles of Apicomplexa: biology and isolation by subcellular fractionation. (2001)
Blackman, MJ; Bannister, LH
Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial. (2001)
Bojang, KA; Milligan, PJ; Pinder, M; Vigneron, L; Alloueche, A; Kester, KE; Ballou, WR; Conway, DJ; Reece, WH; Gothard, P; Yamuah, L; Delchambre, M; Voss, G; Greenwood, BM; Hill, A; McAdam, KP; Tornieporth, N; Cohen, JD; Doherty, T; RTS, S Malaria Vaccine Trial Team
Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen. (2001)
Bruña-Romero, O; González-Aseguinolaza, G; Hafalla, JC; Tsuji, M; Nussenzweig, RS
Detection of malaria liver-stages in mice infected through the bite of a single Anopheles mosquito using a highly sensitive real-time PCR. (2001)
Bruña-Romero, O; Hafalla, JC; González-Aseguinolaza, G; Sano, G; Tsuji, M; Zavala, F
Molecular characterization of the surface layer proteins from Clostridium difficile. (2001)
Calabi, E; Ward, S; Wren, B; Paxton, T; Panico, M; Morris, H; Dell, A; Dougan, G; Fairweather, N
ELISPOT assay to measure antigen-specific murine CD8(+) T cell responses. (2001)
Carvalho, LH; Hafalla, JC; Zavala, F
Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. (2001)
Chibale, K; Haupt, H; Kendrick, H; Yardley, V; Saravanamuthu, A; Fairlamb, AH; Croft, SL
A prognostic model for ovarian cancer. (2001)
Clark, TG; Stewart, ME; Altman, DG; Gabra, H; Smyth, JF
Extreme geographical fixation of variation in the Plasmodium falciparum gamete surface protein gene Pfs48/45 compared with microsatellite loci. (2001)
Conway, DJ; Machado, RL; Singh, B; Dessert, P; Mikes, ZS; Povoa, MM; Oduola, AM; Roper, C
From natural products to drugs. (2001)
Croft, SL
Monitoring drug resistance in leishmaniasis. (2001)
Croft, SL
Antimalarial Chemotherapy: Mechanisms of Action, Resistance and New Directions in Drug Discovery. (2001)
Croft, Simon
Immunological selection for Leishmania (Viannia) braziliensis antigens. (2001)
Cuba Cuba, CA; Ogunkolade, W; Howard, MK; Miles, MA
QSAR study on the contribution of log P and E(s) to the in vitro antiprotozoal activity of glutathione derivatives. (2001)
Daunes, S; D'Silva, C; Kendrick, H; Yardley, V; Croft, SL
Knockout of the rodent malaria parasite chitinase pbCHT1 reduces infectivity to mosquitoes. (2001)
Dessens, JT; Mendoza, J; Claudianos, C; Vinetz, JM; Khater, E; Hassard, S; Ranawaka, GR; Sinden, RE
Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity. (2001)
Dorrell, N; Mangan, JA; Laing, KG; Hinds, J; Linton, D; Al-Ghusein, H; Barrell, BG; Parkhill, J; Stoker, NG; Karlyshev, AV; Butcher, PD; Wren, BW
Leishmania donovani: intraspecific polymorphisms of Sudanese isolates revealed by PCR-based analyses and DNA sequencing. (2001)
El Tai, NO; El Fari, M; Mauricio, I; Miles, MA; Oskam, L; El Safi, SH; Presber, WH; Schönian, G
The Egyptian mongoose, Herpestes ichneumon, is a possible reservoir host of visceral leishmaniasis in eastern Sudan. (2001)
Elnaiem, DA; Hassan, MM; Maingon, R; Nureldin, GH; Mekawi, AM; Miles, M; Ward, RD
Activities of hexadecylphosphocholine (miltefosine), AmBisome, and sodium stibogluconate (Pentostam) against Leishmania donovani in immunodeficient scid mice. (2001)
Escobar, P; Yardley, V; Croft, SL
Molecular epidemiology of tuberculosis: recent developments and applications. (2001)
Fletcher, HA
Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre study. (2001)
Färnert, A; Arez, AP; Babiker, HA; Beck, HP; Benito, A; Björkman, A; Bruce, MC; Conway, DJ; Day, KP; Henning, L; Mercereau-Puijalon, O; Ranford-Cartwright, LC; Rubio, JM; Snounou, G; Walliker, D; Zwetyenga, J; do Rosario, VE
Phylogenetic relationships of flaviviruses correlate with their epidemiology, disease association and biogeography. (2001)
Gaunt, Michael W; Sall, Amadou A; Lamballerie, Xavier de; Falconar, Andrew KI; Dzhivanian, Tatyana I; Gould, Ernest A
Recombinational loss of a ribosomal DNA unit from the circular episome of Entamoeba histolytica HM-1:IMSS. (2001)
Ghosh, S; Zaki, M; Clark, CG; Bhattacharya, S
Activation-induced cell death of human T-cell subsets is mediated by Fas and granzyme B but is independent of TNF-alpha. (2001)
Gorak-Stolinska, P; Truman, JP; Kemeny, DM; Noble, A
Improved production by domain inversion of single-chain Fv antibody fragment against high molecular weight proteoglycan for the radioimmunotargeting of melanoma. (2001)
Hamilton, S; Odili, J; Gundogdu, O; Wilson, GD; Kupsch, JM
Expression and functional characterization of bluetongue virus VP5 protein: role in cellular permeabilization. (2001)
Hassan, SH; Wirblich, C; Forzan, M; Roy, P
Interleukin (IL)-18 promotes the development of chronic gastrointestinal helminth infection by downregulating IL-13. (2001)
Helmby, H; Takeda, K; Akira, S; Grencis, RK
Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1. (2001)
Howell, SA; Withers-Martinez, C; Kocken, CH; Thomas, AW; Blackman, MJ
Demonstration of polysaccharide capsule in Campylobacter jejuni using electron microscopy. (2001)
Karlyshev, AV; McCrossan, MV; Wren, BW
Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes. (2001)
Karlyshev, AV; Oyston, PC; Williams, K; Clark, GC; Titball, RW; Winzeler, EA; Wren, BW
Detection and initial characterization of novel capsular polysaccharide among diverse Campylobacter jejuni strains using alcian blue dye. (2001)
Karlyshev, AV; Wren, BW
In vitro and in vivo activities of aminoadamantane and aminoalkylcyclohexane derivatives against Trypanosoma brucei. (2001)
Kelly, JM; Quack, G; Miles, MM
Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens. (2001)
Lertmemongkolchai, G; Cai, G; Hunter, CA; Bancroft, GJ
Primary structure and sexual stage-specific expression of a LAMMER protein kinase of Plasmodium falciparum. (2001)
Li, JL; Targett, GA; Baker, DA
Deciphering Campylobacter jejuni cell surface interactions from the genome sequence. (2001)
Linton, D; Karlyshev, AV; Wren, BW
In vivo monitoring of intracellular ATP levels in Leishmania donovani promastigotes as a rapid method to screen drugs targeting bioenergetic metabolism. (2001)
Luque-Ortega, JR; Rivero-Lezcano, OM; Croft, SL; Rivas, L
Presence of human T-cell responses to the Mycobacterium leprae 45-kilodalton antigen reflects infection with or exposure to M. leprae. (2001)
Macfarlane, A; Mondragon-Gonzalez, R; Vega-Lopez, F; Wieles, B; de Pena, J; Rodriguez, O; Suarez y de la Torre, R; de Vries, RR; Ottenhoff, TH; Dockrell, HM
Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. (2001)
Martin, MB; Grimley, JS; Lewis, JC; Heath, HT; Bailey, BN; Kendrick, H; Yardley, V; Caldera, A; Lira, R; Urbina, JA; Moreno, SN; Docampo, R; Croft, SL; Oldfield, E
Helicobacter pylori pore-forming cytolysin orthologue TlyA possesses in vitro hemolytic activity and has a role in colonization of the gastric mucosa. (2001)
Martino, MC; Stabler, RA; Zhang, ZW; Farthing, MJ; Wren, BW; Dorrell, N
Genetic typing and phylogeny of the Leishmania donovani complex by restriction analysis of PCR amplified gp63 intergenic regions. (2001)
Mauricio, IL; Gaunt, MW; Stothard, JR; Miles, MA
A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii. (2001)
Miller, SA; Binder, EM; Blackman, MJ; Carruthers, VB; Kim, K
Migration of Plasmodium sporozoites through cells before infection. (2001)
Mota, MM; Pradel, G; Vanderberg, JP; Hafalla, JC; Frevert, U; Nussenzweig, RS; Nussenzweig, V; Rodríguez, A
Polymorphisms in the IkappaB-alpha promoter region and risk of diseases involving inflammation and fibrosis. (2001)
Mozzato-Chamay, N; Corbett, EL; Bailey, RL; Mabey, DC; Raynes, J; Conway, DJ
The gametocyte-activating factor xanthurenic acid stimulates an increase in membrane-associated guanylyl cyclase activity in the human malaria parasite Plasmodium falciparum. (2001)
Muhia, DK; Swales, CA; Deng, W; Kelly, JM; Baker, DA
The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin. (2001)
Murray, PJ; Kranz, M; Ladlow, M; Taylor, S; Berst, F; Holmes, AB; Keavey, KN; Jaxa-Chamiec, A; Seale, PW; Stead, P; Upton, RJ; Croft, SL; Clegg, W; Elsegood, MR
N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. (2001)
Nan, A; Nanayakkara, NP; Walker, LA; Yardley, V; Croft, SL; Ghandehari, H
Fluorescent Plasmodium berghei sporozoites and pre-erythrocytic stages: a new tool to study mosquito and mammalian host interactions with malaria parasites. (2001)
Natarajan, R; Thathy, V; Mota, MM; Hafalla, JC; Ménard, R; Vernick, KD
Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. (2001)
Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; Hamilton, AD
Comparative analysis of Plasmodium reichenowi and P. falciparum erythrocyte-binding proteins reveals selection to maintain polymorphism in the erythrocyte-binding region of EBA-175. (2001)
Ozwara, H; Kocken, CH; Conway, DJ; Mwenda, JM; Thomas, AW
Genome sequence of Yersinia pestis, the causative agent of plague. (2001)
Parkhill, J; Wren, BW; Thomson, NR; Titball, RW; Holden, MT; Prentice, MB; Sebaihia, M; James, KD; Churcher, C; Mungall, KL; Baker, S; Basham, D; Bentley, SD; Brooks, K; Cerdeño-Tárraga, AM; Chillingworth, T; Cronin, A; Davies, RM; Davis, P; Dougan, G; Feltwell, T; Hamlin, N; Holroyd, S; Jagels, K; Karlyshev, AV; Leather, S; Moule, S; Oyston, PC; Quail, M; Rutherford, K; Simmonds, M; Skelton, J; Stevens, K; Whitehead, S; Barrell, BG
Population morphometric analysis of the tropicopolitan bug Triatoma rubrofasciata and relationships with old world species of Triatoma: evidence of New World ancestry. (2001)
Patterson, JS; Schofield, CJ; Dujardin, JP; Miles, MA
Strong diversifying selection on domains of the Plasmodium falciparum apical membrane antigen 1 gene. (2001)
Polley, SD; Conway, DJ
Yersinia pestis pFra shows biovar-specific differences and recent common ancestry with a Salmonella enterica serovar Typhi plasmid. (2001)
Prentice, MB; James, KD; Parkhill, J; Baker, SG; Stevens, K; Simmonds, MN; Mungall, KL; Churcher, C; Oyston, PC; Titball, RW; Wren, BW; Wain, J; Pickard, D; Hien, TT; Farrar, JJ; Dougan, G
Characterization of the lipopolysaccharide of Yersinia pestis. (2001)
Prior, JL; Hitchen, PG; Williamson, DE; Reason, AJ; Morris, HR; Dell, A; Wren, BW; Titball, RW
The failure of different strains of Yersinia pestis to produce lipopolysaccharide O-antigen under different growth conditions is due to mutations in the O-antigen gene cluster. (2001)
Prior, JL; Parkhill, J; Hitchen, PG; Mungall, KL; Stevens, K; Morris, HR; Reason, AJ; Oyston, PC; Dell, A; Wren, BW; Titball, RW
Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4. (2001)
Prior, RG; Klasson, L; Larsson, P; Williams, K; Lindler, L; Sjöstedt, A; Svensson, T; Tamas, I; Wren, BW; Oyston, PC; Andersson, SG; Titball, RW
Acute-phase HDL in phospholipid transfer protein (PLTP)-mediated HDL conversion. (2001)
Pussinen, PJ; Malle, E; Metso, J; Sattler, W; Raynes, JG; Jauhiainen, M
Malaria vectors in the municipality of Serra do Navio, State of Amapá, Amazon Region, Brazil. (2001)
Póvoa, M; Wirtz, R; Lacerda, R; Miles, M; Warhurst, D
Production of matrix metalloproteinases in response to mycobacterial infection. (2001)
Quiding-Järbrink, M; Smith, DA; Bancroft, GJ
Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. (2001)
Ren, H; Grady, S; Gamenara, D; Heinzen, H; Moyna, P; Croft, SL; Kendrick, H; Yardley, V; Moyna, G
2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity. (2001)
Salmon-Chemin, L; Buisine, E; Yardley, V; Kohler, S; Debreu, MA; Landry, V; Sergheraert, C; Croft, SL; Krauth-Siegel, RL; Davioud-Charvet, E
Swift development of protective effector functions in naive CD8(+) T cells against malaria liver stages. (2001)
Sano, G; Hafalla, JC; Morrot, A; Abe, R; Lafaille, JJ; Zavala, F
Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates. (2001)
Smith, DA; Parish, T; Stoker, NG; Bancroft, GJ
Human dendritic cells genetically engineered to express a melanoma polyepitope DNA vaccine induce multiple cytotoxic T-cell responses. (2001)
Smith, SG; Patel, PM; Porte, J; Selby, PJ; Jackson, AM
The response of human dendritic cells to recombinant adenovirus, recombinant Mycobacterium bovis Bacillus Calmette Guerin and biolistic methods of antigen delivery: different induction of contact-dependant and soluble signals. (2001)
Smith, SG; Patel, PM; Selby, PJ; Jackson, AM
Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1, -2, and -3. (2001)
Stix, B; Kähne, T; Sletten, K; Raynes, J; Roessner, A; Röcken, C
Stevor transcripts from Plasmodium falciparum gametocytes encode truncated polypeptides. (2001)
Sutherland, CJ
RGD tripeptide of bluetongue virus VP7 protein is responsible for core attachment to Culicoides cells. (2001)
Tan, BH; Nason, E; Staeuber, N; Jiang, W; Monastryrskaya, K; Roy, P
Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae. (2001)
Targett, G; Drakeley, C; Jawara, M; von Seidlein, L; Coleman, R; Deen, J; Pinder, M; Doherty, T; Sutherland, C; Walraven, G; Milligan, P
Detection of bancroftian filariasis in human blood samples from Sorsogon province, the Philippines by polymerase chain reaction. (2001)
Torres, EP; Ramirez, BL; Salazar, F; Pasay, MC; Alamares, JG; Santiago, ML; Hafalla, JC
Genetic Variation among Human Isolates of Uninucleated Cyst-Producing Entamoeba Species. (2001)
Verweij, JJ; Polderman, AM; Clark, CG
Maintenance of Golgi structure and function depends on the integrity of ER export. (2001)
Ward, TH; Polishchuk, RS; Caplan, S; Hirschberg, K; Lippincott-Schwartz, J
Random errors in the measurement of 10 cardiovascular risk factors. (2001)
Whitlock, G; Clark, T; Vander Hoorn, S; Rodgers, A; Jackson, R; Norton, R; MacMahon, S
Post genome analysis of Campylobacter jejuni. (2001)
Wren, BW; Linton, D; Dorrell, N; Karlyshev, AV
Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents. (2001)
Wright, CW; Addae-Kyereme, J; Breen, AG; Brown, JE; Cox, MF; Croft, SL; Gökçek, Y; Kendrick, H; Phillips, RM; Pollet, PL
Isolation and characterization of polymorphic DNA from Entamoeba histolytica. (2001)
Zaki, M; Clark, CG
Adrenaline suppression of the macrophage nitric oxide response to lipopolysaccharide is associated with differential regulation of tumour necrosis factor-alpha and interleukin-10. (2001)
Zinyama, RB; Bancroft, GJ; Sigola, LB
Terpenoids from Guarea rhophalocarpa. (2001)
del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN
Risk factors for gametocyte carriage in Gambian children. (2001)
von Seidlein, L; Drakeley, C; Greenwood, B; Walraven, G; Targett, G