Items where Author is "Warhurst, D"
Number of items: 84.
2016
Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V. (2016)
Oguike, Mary C; Falade, Catherine O; Shu, Elvis; Enato, Izehiuwa G; Watila, Ismaila; Baba, Ebenezer S; Bruce, Jane; Webster, Jayne; Hamade, Prudence; Meek, Sylvia; Chandramohan, Daniel; Sutherland, Colin J; Warhurst, David; Roper, Cally
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Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance. (2016)
Warhurst, David C; Craig, John C; Raheem, K Saki
2015
The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine. (2015)
Henriques, Gisela; van Schalkwyk, Donelly A; Burrow, Rebekah; Warhurst, David C; Thompson, Eloise; Baker, David A; Fidock, David A; Hallett, Rachel; Flueck, Christian; Sutherland, Colin J
2014
Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients. (2014)
Gadalla, Nahla B; Malmberg, Maja; Adam, Ishag; Oguike, Mary C; Beshir, Khalid; Elzaki, Salah-Eldin; Mukhtar, Izdihar; Gadalla, Amal A; Warhurst, David C; Ngasala, Billy; Mårtensson, Andreas; El-Sayed, Badria B; Gil, J Pedro; Sutherland, Colin J
Cryptosporidium prevalence and risk factors among mothers and infants 0 to 6 months in rural and semi-rural Northwest Tanzania: a prospective cohort study. (2014)
Pedersen, Sarah H; Wilkinson, Amanda L; Andreasen, Aura; Warhurst, David C; Kinung'hi, Safari M; Urassa, Mark; Mkwashapi, Denna M; Todd, Jim; Changalucha, John; McDermid, Joann M
In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates. (2014)
Rout, Subhashree; Warhurst, David Charles; Suar, Mrutyunjay; Mahapatra, Rajani Kanta
2011
Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine. (2011)
Gadalla, Nahla B; Adam, Ishag; Elzaki, Salah-Eldin; Bashir, Sahar; Mukhtar, Izdihar; Oguike, Mary; Gadalla, Amal; Mansour, Fathi; Warhurst, David; El-Sayed, Badria B; Sutherland, Colin J
2010
Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum. (2010)
Gadalla, Nahla B; Elzaki, Salah Eldin; Mukhtar, Ebtihal; Warhurst, David C; El-Sayed, Badria; Sutherland, Colin J
Amebic Infections. (2010)
Warhurst, D
Malaria: mode of action of drugs and resistance mechanisms. (2010)
Warhurst, D
Introduction to malaria. (2010)
Warhurst, D
Major Tropical Syndromes: The gastrointestinal tract. (2010)
Warhurst, DC
Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate. (2010)
de Souza, J Brian; Okomo, Uduak; Alexander, Neal D; Aziz, Naveed; Owens, Benjamin MJ; Kaur, Harparkash; Jasseh, Momodou; Muangnoicharoen, Sant; Sumariwalla, Percy F; Warhurst, David C; Ward, Stephen A; Conway, David J; Ulloa, Luis; Tracey, Kevin J; Foxwell, Brian MJ; Kaye, Paul M; Walther, Michael
2009
Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola. (2009)
Menegon, Michela; Pearce, Richard J; Inojosa, Walter O; Pisani, Vincenzo; Abel, Paulo M; Matondo, Alexandre; Bisoffi, Zeno; Majori, Giancarlo; Ord, Rosalynn; Warhurst, David C; Roper, Cally; Severini, Carlo
Potentially Pathogenic Free-living Amoebae. (2009)
Warhurst, DC
2007
Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. (2007)
Fivelman, QL; Adagu, IS; Warhurst, DC
Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. (2007)
Fivelman, Quinton L; Adagu, Ipemida S; Warhurst, David C
Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity. (2007)
Siddiqui, Ruqaiyyah; Matin, Abdul; Warhurst, David; Stins, Monique; Khan, Naveed Ahmed
Understanding resistance to antimalarial 4-aminoquinolines, cinchona alkaloids and the highly hydrophobic arylaminoalcohols. (2007)
Warhurst, DC
Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum. Role of beta-haematin inhibition and drug concentration in vacuolar water- and lipid-phases. (2007)
Warhurst, David C; Craig, John C; Adagu, Ipemida S; Guy, R Kiplin; Madrid, Peter B; Fivelman, Quinton L
Malaria (CDROM, 3rd Edition). (2007)
Warhurst, D.(acknowledged)
2006
Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania. (2006)
Alifrangis, Michael; Dalgaard, Michael B; Lusingu, John P; Vestergaard, Lasse S; Staalsoe, Trine; Jensen, Anja TR; Enevold, Anders; Rønn, Anita M; Khalil, Insaf F; Warhurst, David C; Lemnge, Martha M; Theander, Thor G; Bygbjerg, Ib C
PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX. (2006)
Bray, Patrick G; Mungthin, Mathirut; Hastings, Ian M; Biagini, Giancarlo A; Saidu, Dauda K; Lakshmanan, Viswanathan; Johnson, David J; Hughes, Ruth H; Stocks, Paul A; O'Neill, Paul M; Fidock, David A; Warhurst, David C; Ward, Stephen A
Variation in Plasmodium falciparum susceptibility to the cinchona alkaloids is determined by polymorphisms in PfCRT. (2006)
Griffin, CE; Warhurst, DC; Cooper, RA
Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo. (2006)
Stachulski, Andrew V; Berry, Neil G; Lilian Low, AC; Moores, Shelley L; Row, Eleanor; Warhurst, David C; Adagu, Ipemida S; Rossignol, Jean-François
2004
Mechanisms of action of nitazoxanide and related drugs against helminths. (2004)
Atherton, Richard Roy Dalzell
Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum. (2004)
Fivelman, Quinton L; Adagu, Ipemida S; Warhurst, David C
Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells. (2004)
Jayasekera, Samantha; Sissons, James; Tucker, Julie; Rogers, Claire; Nolder, Debbie; Warhurst, David; Alsam, Selwa; White, Jonathan ML; Higgins, EM; Khan, Naveed Ahmed
Laboratory Procedures for Diagnosis of Malaria. (2004)
Warhurst, DC; Williams, JE
Fatal granulomatous amoebic encephalitis: cutaneous and intracerebral Balamuthia mandrillaris. (2004)
White, JML; Barker, RD; Salisbury, JR; Fife, AJ; Lucas, S; Warhurst, DC; Higgins, EM
Granulomatous amoebic encephalitis. (2004)
White, JML; Barker, RD; Salisbury, JR; Fife, AJ; Lucas, SB; Warhurst, DC; Higgins, EM
2003
Drug uptake, sensitivity, interaction studies and resistance associated mutations in Plasmodium falciparum. (2003)
Fivelman, QL
Enhancement of the antiplasmodial activity of quassin by transformation into a gamma-lactone. (2003)
Lang'at-Thoruwa, Caroline; Kirby, Geoffrey C; Phillipson, J David; Warhurst, David C; Watt, Robert A; Wright, Colin W
[Presence of the double pfmdr1 mutation 86Tyr and 1246 Tyr in clones of a chloroquine-resistant west African isolate of Plasmodium falciparum]. (2003)
Pinheiro, L; Franco, S; Adagu, IS; Rosa, R; Rosário, VE; Warhurst, DC
Back-calculation of the number of inoculated Plasmodium falciparum parasites in a documented case of needlestick malaria in a French nurse. (2003)
Tarantola, A; Warhurst, DC; Rachline, A
Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine. (2003)
Warhurst, David C
The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids. (2003)
Warhurst, David C; Craig, John C; Adagu, Ipemida S; Meyer, David J; Lee, Sylvia Y
Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties. (2003)
Warhurst, David C; Steele, Jonathan CP; Adagu, Ipemida S; Craig, John C; Cullander, Christopher
2002
In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis. (2002)
Adagu, I Sullayman; Nolder, Deborah; Warhurst, David C; Rossignol, Jean-François
Mutations in dhfr in Plasmodium falciparum infections selected by chlorproguanil-dapsone treatment. (2002)
Curtis, J; Maxwell, CA; Msuya, FHM; Mkongewa, S; Alloueche, A; Warhurst, DC
In vitro antiplasmodial activity of extracts of Argentinian plants. (2002)
Debenedetti, S; Muschietti, L; van Baren, C; Clavin, M; Broussalis, A; Martino, V; Houghton, PJ; Warhurst, D; Steele, J
Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria. (2002)
Fivelman, Quinton L; Butcher, Geoffrey A; Adagu, Ipemida S; Warhurst, David C; Pasvol, Geoffrey
A multiplex allele specific polymerase chain reaction (MAS-PCR) on the dihydrofolate reductase gene for the detection of Cryptosporidium parvum genotypes 1 and 2. (2002)
Gile, M; Warhurst, DC; Webster, KA; West, DM; Marshall, JA
Drug-resistance mutations in the dihydropteroate synthetase of Plasmodium falciparum in samples from north-east Tanzania: Society Meeting at Manson House, London, 13 December 2001: Research in progress: short presentation [Poster Presentation]. (2002)
Kiani, SA; Curtis, J; Warhurst, DC
Treatment of uncomplicated malaria:[Letter to editor: Authors reply]. (2002)
Omar, S; Warhurst, DC
Drug-susceptibility and molecular characterization of epidemic and endemic malaria in Kenya. (2002)
Omar, SA
TV or not TV? (2002)
Smith, A; Portsmouth, S; Curran, B; Warhurst, D; Kell, P; Saulsbury, N
Two novel assays for the detection of haemin-binding properties of antimalarials evaluated with compounds isolated from medicinal plants. (2002)
Steele, JCP; Phelps, RJ; Simmonds, MSJ; Warhurst, DC; Meyer, DJ
Indole and beta-carboline alkaloids from Geissospermum sericeum. (2002)
Steele, Jonathan CP; Veitch, Nigel C; Kite, Geoffrey C; Simmonds, Monique SJ; Warhurst, David C
Gambian children successfully treated with chloroquine can harbor and transmit Plasmodium falciparum gametocytes carrying resistance genes. (2002)
Sutherland, Colin J; Alloueche, Ali; Curtis, Jill; Drakeley, Chris J; Ord, Rosalynn; Duraisingh, Manoj; Greenwood, Brian M; Pinder, Margaret; Warhurst, David; Targett, Geoffrey AT
Restricted genetic and antigenic diversity of Plasmodium falciparum under mesoendemic transmission in the Venezuelan Amazon. (2002)
Tami, A; Grundmann, H; Sutherland, C; McBride, JS; Cavanagh, DR; Campos, E; Snounou, G; Barnabé, C; Tibayrenc, M; Warhurst, DC
Potentially Pathogenic Free-living Amebae. (2002)
Warhurst, DC
Resistance to antifolates in Plasmodium falciparum, the causative agent of tropical malaria. (2002)
Warhurst, David C
Lysosomes and drug resistance in malaria. (2002)
Warhurst, David C; Craig, John C; Adagu, Ipemida S
Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. (2002)
del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Marley, Dereck; Kirby, Geoffrey C; Warhurst, David C
2001
Plasmodium falciparum: linkage disequilibrium between loci in chromosomes 7 and 5 and chloroquine selective pressure in Northern Nigeria. (2001)
Adagu, IS; Warhurst, DC
Monitoring antimalarial drug resistance (report of a WHO Consultation). (2001)
Bloland, P; D'Alessandro, U; Ringwald, P; Watkins, W (Technical Advisers: Warhurst, D; et al)
Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210. (2001)
Hankins, EG; Warhurst, DC; Sibley, CH
Plasmodium falciparum in Kenya: high prevalence of drug-resistance-associated polymorphisms in hospital admissions with severe malaria in an epidemic area. (2001)
Omar, SA; Adagu, IS; Gump, DW; Ndaru, NP; Warhurst, DC
Can pretreatment screening for dhps and dhfr point mutations in Plasmodium falciparum infections be used to predict sulfadoxine-pyrimethamine treatment failure? (2001)
Omar, SA; Adagu, IS; Warhurst, DC
Co-trimoxazole compared with sulfadoxine-pyrimethamine in the treatment of uncomplicated malaria in Kenyan children. (2001)
Omar, SA; Bakari, A; Owiti, A; Adagu, IS; Warhurst, DC
Malaria vectors in the municipality of Serra do Navio, State of Amapá, Amazon Region, Brazil. (2001)
Póvoa, M; Wirtz, R; Lacerda, R; Miles, M; Warhurst, D
New developments: chloroquine-resistance in Plasmodium falciparum. (2001)
Warhurst, D
A molecular marker for chloroquine-resistant falciparum malaria. (2001)
Warhurst, DC
The parasite. (2001)
Warhurst, DC
Mode of action of artemether lumefantrine (COARTEM): The sole, fixed, oral ADCC and its role in combatting multidrug resistance. (2001)
Warhurst, DC; Adagu, IS; Beck, HP; Duraisingh, MT; Kirby, GC; von Seidlein, L; Wright, CW
Rational use of drugs against Plasmodium falciparum. (2001)
Warhurst, DC; Duraisingh, MT
Protozoan parasites of the mouse intestinal tract. (2001)
Williams, JE; Warhurst, DC
Protozoan parasites of the intestinal tract of the cockroach, Periplaneta americana. (2001)
Williams, JE; Warhurst, DC
Terpenoids from Guarea rhophalocarpa. (2001)
del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN
1997
Field chloroquine-resistance determinants. (1997)
Adagu, I; Ogala, W; Carucci, D; Duraisingh, M; Warhurst, D
Field chloroquine-resistance determinants. (1997)
Adagu, IS; Ogala, WN; Carucci, DJ; Duraisingh, MT; Warhurst, DC
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