Year Item Type Full Text

Bibliographic data only

In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis. (2002) Adagu, I Sullayman; Nolder, Deborah; Warhurst, David C; Rossignol, Jean-François

Field chloroquine-resistance determinants. (1997) Adagu, I; Ogala, W; Carucci, D; Duraisingh, M; Warhurst, D

Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania. (2006) Alifrangis, Michael; Dalgaard, Michael B; Lusingu, John P; Vestergaard, Lasse S; Staalsoe, Trine; Jensen, Anja TR; Enevold, Anders; Rønn, Anita M; Khalil, Insaf F; Warhurst, David C; Lemnge, Martha M; Theander, Thor G; Bygbjerg, Ib C

PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX. (2006) Bray, Patrick G; Mungthin, Mathirut; Hastings, Ian M; Biagini, Giancarlo A; Saidu, Dauda K; Lakshmanan, Viswanathan; Johnson, David J; Hughes, Ruth H; Stocks, Paul A; O'Neill, Paul M; Fidock, David A; Warhurst, David C; Ward, Stephen A

Mutations in dhfr in Plasmodium falciparum infections selected by chlorproguanil-dapsone treatment. (2002) Curtis, J; Maxwell, CA; Msuya, FHM; Mkongewa, S; Alloueche, A; Warhurst, DC

In vitro antiplasmodial activity of extracts of Argentinian plants. (2002) Debenedetti, S; Muschietti, L; van Baren, C; Clavin, M; Broussalis, A; Martino, V; Houghton, PJ; Warhurst, D; Steele, J

Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. (2007) Fivelman, QL; Adagu, IS; Warhurst, DC

Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. (2007) Fivelman, Quinton L; Adagu, Ipemida S; Warhurst, David C

Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum. (2004) Fivelman, Quinton L; Adagu, Ipemida S; Warhurst, David C

The Intra-Host Dynamics of Pfcrt and Pfmdr-1 Alleles Following Antimalarial Treatment in Sudanese Patients. (2008) Gadalla, NB; Adam, I; Warhurst, DC; el-Sayed, BB; Sutherland, CJ

Variation in Plasmodium falciparum susceptibility to the cinchona alkaloids is determined by polymorphisms in PfCRT. (2006) Griffin, CE; Warhurst, DC; Cooper, RA

Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids. (2012) Griffin, Carol E; Hoke, Jonathan M; Samarakoon, Upeka; Duan, Junhui; Mu, Jianbing; Ferdig, Michael T; Warhurst, David C; Cooper, Roland A

Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210. (2001) Hankins, EG; Warhurst, DC; Sibley, CH

Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells. (2004) Jayasekera, Samantha; Sissons, James; Tucker, Julie; Rogers, Claire; Nolder, Debbie; Warhurst, David; Alsam, Selwa; White, Jonathan ML; Higgins, EM; Khan, Naveed Ahmed

Drug-resistance mutations in the dihydropteroate synthetase of Plasmodium falciparum in samples from north-east Tanzania: Society Meeting at Manson House, London, 13 December 2001: Research in progress: short presentation [Poster Presentation]. (2002) Kiani, SA; Curtis, J; Warhurst, DC

Enhancement of the antiplasmodial activity of quassin by transformation into a gamma-lactone. (2003) Lang'at-Thoruwa, Caroline; Kirby, Geoffrey C; Phillipson, J David; Warhurst, David C; Watt, Robert A; Wright, Colin W

Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates. (2005) Maghsood, Amir Hossein; Sissons, James; Rezaian, Mostafa; Nolder, Debbie; Warhurst, David; Khan, Naveed Ahmed

Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola. (2009) Menegon, Michela; Pearce, Richard J; Inojosa, Walter O; Pisani, Vincenzo; Abel, Paulo M; Matondo, Alexandre; Bisoffi, Zeno; Majori, Giancarlo; Ord, Rosalynn; Warhurst, David C; Roper, Cally; Severini, Carlo

Treatment of uncomplicated malaria:[Letter to editor: Authors reply]. (2002) Omar, S; Warhurst, DC

Plasmodium falciparum in Kenya: high prevalence of drug-resistance-associated polymorphisms in hospital admissions with severe malaria in an epidemic area. (2001) Omar, SA; Adagu, IS; Gump, DW; Ndaru, NP; Warhurst, DC

Can pretreatment screening for dhps and dhfr point mutations in Plasmodium falciparum infections be used to predict sulfadoxine-pyrimethamine treatment failure? (2001) Omar, SA; Adagu, IS; Warhurst, DC

Co-trimoxazole compared with sulfadoxine-pyrimethamine in the treatment of uncomplicated malaria in Kenyan children. (2001) Omar, SA; Bakari, A; Owiti, A; Adagu, IS; Warhurst, DC

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates. (2014) Rout, Subhashree; Warhurst, David Charles; Suar, Mrutyunjay; Mahapatra, Rajani Kanta

Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity. (2007) Siddiqui, Ruqaiyyah; Matin, Abdul; Warhurst, David; Stins, Monique; Khan, Naveed Ahmed

TV or not TV? (2002) Smith, A; Portsmouth, S; Curran, B; Warhurst, D; Kell, P; Saulsbury, N

Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo. (2006) Stachulski, Andrew V; Berry, Neil G; Lilian Low, AC; Moores, Shelley L; Row, Eleanor; Warhurst, David C; Adagu, Ipemida S; Rossignol, Jean-François

Two novel assays for the detection of haemin-binding properties of antimalarials evaluated with compounds isolated from medicinal plants. (2002) Steele, JCP; Phelps, RJ; Simmonds, MSJ; Warhurst, DC; Meyer, DJ

Indole and beta-carboline alkaloids from Geissospermum sericeum. (2002) Steele, Jonathan CP; Veitch, Nigel C; Kite, Geoffrey C; Simmonds, Monique SJ; Warhurst, David C

Back-calculation of the number of inoculated Plasmodium falciparum parasites in a documented case of needlestick malaria in a French nurse. (2003) Tarantola, A; Warhurst, DC; Rachline, A

New developments: chloroquine-resistance in Plasmodium falciparum. (2001) Warhurst, D

Amebic Infections. (2010) Warhurst, D

Malaria: mode of action of drugs and resistance mechanisms. (2010) Warhurst, D

Introduction to malaria. (2010) Warhurst, D

Advances in mode of action of antimalarials and resistance mechanisms - part 1 of 2. (2013) Warhurst, DC

Advances in mode of action of antimalarials and resistance mechanisms - part 2 of 2. (2013) Warhurst, DC

Understanding resistance to antimalarial 4-aminoquinolines, cinchona alkaloids and the highly hydrophobic arylaminoalcohols. (2007) Warhurst, DC

Major Tropical Syndromes: The gastrointestinal tract. (2010) Warhurst, DC

Potentially Pathogenic Free-living Amoebae. (2009) Warhurst, DC

Potentially Pathogenic Free-living Amebae. (2002) Warhurst, DC

The parasite. (2001) Warhurst, DC

The Parasite. (2008) Warhurst, DC

Rational use of drugs against Plasmodium falciparum. (2001) Warhurst, DC; Duraisingh, MT

Laboratory Procedures for Diagnosis of Malaria. (2004) Warhurst, DC; Williams, JE

Resistance to antifolates in Plasmodium falciparum, the causative agent of tropical malaria. (2002) Warhurst, David C

Lysosomes and drug resistance in malaria. (2002) Warhurst, David C; Craig, John C; Adagu, Ipemida S

Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties. (2003) Warhurst, David C; Steele, Jonathan CP; Adagu, Ipemida S; Craig, John C; Cullander, Christopher

Malaria (CDROM, 3rd Edition). (2007) Warhurst, D.(acknowledged)

Fatal granulomatous amoebic encephalitis: cutaneous and intracerebral Balamuthia mandrillaris. (2004) White, JML; Barker, RD; Salisbury, JR; Fife, AJ; Lucas, S; Warhurst, DC; Higgins, EM

Granulomatous amoebic encephalitis. (2004) White, JML; Barker, RD; Salisbury, JR; Fife, AJ; Lucas, SB; Warhurst, DC; Higgins, EM

Protozoan parasites of the mouse intestinal tract. (2001) Williams, JE; Warhurst, DC

Terpenoids from Guarea rhophalocarpa. (2001) del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN

Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Marley, Dereck; Kirby, Geoffrey C; Warhurst, David C

Public

Plasmodium falciparum: linkage disequilibrium between loci in chromosomes 7 and 5 and chloroquine selective pressure in Northern Nigeria. (2001) Adagu, IS; Warhurst, DC

Standardisation and evaluation of differential diagnostic systems for the detection of Entamoeba histolytica and Entamoeba dispar. (1999) Aguirre-Beltran, Aura Georgina

Mechanisms of action of nitazoxanide and related drugs against helminths. (2004) Atherton, Richard Roy Dalzell

Monitoring antimalarial drug resistance (report of a WHO Consultation). (2001) Bloland, P; D'Alessandro, U; Ringwald, P; Watkins, W (Technical Advisers: Warhurst, D; et al)

Drug uptake, sensitivity, interaction studies and resistance associated mutations in Plasmodium falciparum. (2003) Fivelman, QL

Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria. (2002) Fivelman, Quinton L; Butcher, Geoffrey A; Adagu, Ipemida S; Warhurst, David C; Pasvol, Geoffrey

Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine. (2011) Gadalla, Nahla B; Adam, Ishag; Elzaki, Salah-Eldin; Bashir, Sahar; Mukhtar, Izdihar; Oguike, Mary; Gadalla, Amal; Mansour, Fathi; Warhurst, David; El-Sayed, Badria B; Sutherland, Colin J

Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum. (2010) Gadalla, Nahla B; Elzaki, Salah Eldin; Mukhtar, Ebtihal; Warhurst, David C; El-Sayed, Badria; Sutherland, Colin J

Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients. (2014) Gadalla, Nahla B; Malmberg, Maja; Adam, Ishag; Oguike, Mary C; Beshir, Khalid; Elzaki, Salah-Eldin; Mukhtar, Izdihar; Gadalla, Amal A; Warhurst, David C; Ngasala, Billy; Mårtensson, Andreas; El-Sayed, Badria B; Gil, J Pedro; Sutherland, Colin J

A multiplex allele specific polymerase chain reaction (MAS-PCR) on the dihydrofolate reductase gene for the detection of Cryptosporidium parvum genotypes 1 and 2. (2002) Gile, M; Warhurst, DC; Webster, KA; West, DM; Marshall, JA

The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine. (2015) Henriques, Gisela; van Schalkwyk, Donelly A; Burrow, Rebekah; Warhurst, David C; Thompson, Eloise; Baker, David A; Fidock, David A; Hallett, Rachel; Flueck, Christian; Sutherland, Colin J

Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V. (2016) Oguike, Mary C; Falade, Catherine O; Shu, Elvis; Enato, Izehiuwa G; Watila, Ismaila; Baba, Ebenezer S; Bruce, Jane; Webster, Jayne; Hamade, Prudence; Meek, Sylvia; Chandramohan, Daniel; Sutherland, Colin J; Warhurst, David; Roper, Cally ['material/summary:fileicon_text/html' not defined]

Drug-susceptibility and molecular characterization of epidemic and endemic malaria in Kenya. (2002) Omar, SA

Cryptosporidium prevalence and risk factors among mothers and infants 0 to 6 months in rural and semi-rural Northwest Tanzania: a prospective cohort study. (2014) Pedersen, Sarah H; Wilkinson, Amanda L; Andreasen, Aura; Warhurst, David C; Kinung'hi, Safari M; Urassa, Mark; Mkwashapi, Denna M; Todd, Jim; Changalucha, John; McDermid, Joann M

[Presence of the double pfmdr1 mutation 86Tyr and 1246 Tyr in clones of a chloroquine-resistant west African isolate of Plasmodium falciparum]. (2003) Pinheiro, L; Franco, S; Adagu, IS; Rosa, R; Rosário, VE; Warhurst, DC

Studies on malaria in Serra do Navioegion, Amapa State, Brazil. (1993) Povoa, Marinete Marins

Malaria vectors in the municipality of Serra do Navio, State of Amapá, Amazon Region, Brazil. (2001) Póvoa, M; Wirtz, R; Lacerda, R; Miles, M; Warhurst, D

Gambian children successfully treated with chloroquine can harbor and transmit Plasmodium falciparum gametocytes carrying resistance genes. (2002) Sutherland, Colin J; Alloueche, Ali; Curtis, Jill; Drakeley, Chris J; Ord, Rosalynn; Duraisingh, Manoj; Greenwood, Brian M; Pinder, Margaret; Warhurst, David; Targett, Geoffrey AT

Restricted genetic and antigenic diversity of Plasmodium falciparum under mesoendemic transmission in the Venezuelan Amazon. (2002) Tami, A; Grundmann, H; Sutherland, C; McBride, JS; Cavanagh, DR; Campos, E; Snounou, G; Barnabé, C; Tibayrenc, M; Warhurst, DC

A molecular marker for chloroquine-resistant falciparum malaria. (2001) Warhurst, DC

Mode of action of artemether lumefantrine (COARTEM): The sole, fixed, oral ADCC and its role in combatting multidrug resistance. (2001) Warhurst, DC; Adagu, IS; Beck, HP; Duraisingh, MT; Kirby, GC; von Seidlein, L; Wright, CW

Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine. (2003) Warhurst, David C

Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum. Role of beta-haematin inhibition and drug concentration in vacuolar water- and lipid-phases. (2007) Warhurst, David C; Craig, John C; Adagu, Ipemida S; Guy, R Kiplin; Madrid, Peter B; Fivelman, Quinton L

The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids. (2003) Warhurst, David C; Craig, John C; Adagu, Ipemida S; Meyer, David J; Lee, Sylvia Y

Influence of LAR and VAR on Para-Aminopyridine Antimalarials Targetting Haematin in Chloroquine-Resistance. (2016) Warhurst, David C; Craig, John C; Raheem, K Saki

Protozoan parasites of the intestinal tract of the cockroach, Periplaneta americana. (2001) Williams, JE; Warhurst, DC

Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate. (2010) de Souza, J Brian; Okomo, Uduak; Alexander, Neal D; Aziz, Naveed; Owens, Benjamin MJ; Kaur, Harparkash; Jasseh, Momodou; Muangnoicharoen, Sant; Sumariwalla, Percy F; Warhurst, David C; Ward, Stephen A; Conway, David J; Ulloa, Luis; Tracey, Kevin J; Foxwell, Brian MJ; Kaye, Paul M; Walther, Michael

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Field chloroquine-resistance determinants. (1997) Adagu, IS; Ogala, WN; Carucci, DJ; Duraisingh, MT; Warhurst, DC picture_as_pdf

Direct evidence that asparagine at position 108 of the Plasmodium falciparum dihydrofolate reductase is involved in resistance to antifolate drugs in Tanzania. (1996) Curtis, J; Duraisingh, MT; Trigg, JK; Mbwana, H; Warhurst, DC; Curtis, CF picture_as_pdf

In vitro antiplasmodial effects of diospyrin, a plant-derived naphthoquinoid, and a novel series of derivatives. (1995) Hazra, B; Ghosh, R; Banerjee, A; Kirby, GC; Warhurst, DC; Phillipson, JD picture_as_pdf

Pathogenic Naegleria amoebae in the waters of Bath: a fatality and its consequences. (1991) Kilvington, S; Mann, P; Warhurst, D picture_as_pdf

Synthesis of some stable ozonides with anti-malarial activity. (1992) de Almeida Barbosa, L.-, C; Cutler, D; Mann, J; Kirby, GC; Warhurst, DC picture_as_pdf