Items where Author is "Wren, Brendan W"

Year Item Type Full Text

2023

Campylobacter jejuni Modulates Reactive Oxygen Species Production and NADPH Oxidase 1 Expression in Human Intestinal Epithelial Cells. (2023) Hong, Geunhye; Davies, Cadi; Omole, Zahra; Liaw, Janie; Grabowska, Anna D; Canonico, Barbara; Corcionivoschi, Nicolae; Wren, Brendan W; Dorrell, Nick; Elmi, Abdi; Gundogdu, Ozan

A combinatorial DNA assembly approach to biosynthesis of N-linked glycans in E. coli. (2023) Passmore, Ian J; Faulds-Pain, Alexandra; Abouelhadid, Sherif; Harrison, Mark A; Hall, Catherine L; Hitchen, Paul; Dell, Anne; Heap, John T; Wren, Brendan W

2022

Defining the Genes Required for Survival of Mycobacterium bovis in the Bovine Host Offers Novel Insights into the Genetic Basis of Survival of Pathogenic Mycobacteria. (2022) Gibson, Amanda J; Stiens, Jennifer; Passmore, Ian J; Faulkner, Valwynne; Miculob, Josephous; Willcocks, Sam; Coad, Michael; Berg, Stefan; Werling, Dirk; Wren, Brendan W; Nobeli, Irene; Villarreal-Ramos, Bernardo; Kendall, Sharon L

Characterising regulation of virulence factors affecting the interaction between Clostridioides difficile and the intestinal microbiome. (2022) Harrison, MA

Campylobacter jejuni modulates reactive oxygen species production and NADPH oxidase 1 expression in human intestinal epithelial cells. (2022) Hong, geung; Davies, cadi; Omole, zahra; Liaw, janie; grabowska, anna; Canonico, barbara; corcionivoschi, Nicolae; Wren, brendan; Dorrell, nick; Elmi, abdi; Gundogdu, Ozan

Strain Specific Variations in Acinetobacter baumannii Complement Sensitivity. (2022) Kamuyu, Gathoni; Ercoli, Giuseppe; Ramos-Sevillano, Elisa; Willcocks, Sam; Kewcharoenwong, Chidchamai; Kiratisin, Pattarachai; Taylor, Peter W; Wren, Brendan W; Lertmemongkolchai, Ganjana; Stabler, Richard A; Brown, Jeremy S

Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines. (2022) Kay, Emily J; Mauri, Marta; Willcocks, Sam J; Scott, Timothy A; Cuccui, Jon; Wren, Brendan W

Survival of Campylobacter jejuni 11168H in Acanthamoebae castellanii Provides Mechanistic Insight into Host Pathogen Interactions. (2022) Nasher, Fauzy; Lehri, Burhan; Horney, Megan F; Stabler, Richard A; Wren, Brendan W

Transient internalization of Campylobacter jejuni in Amoebae enhances subsequent invasion of human cells. (2022) Nasher, Fauzy; Wren, Brendan W

Acinetobacter nosocomialis Causes as Severe Disease as Acinetobacter baumannii in Northeast Thailand: Underestimated Role of A. nosocomialis in Infection. (2022) Nithichanon, Arnone; Kewcharoenwong, Chidchamai; Da-Oh, Hudadini; Surajinda, Sirithorn; Khongmee, Aranya; Koosakunwat, Surathinee; Wren, Brendan W; Stabler, Richard A; Brown, Jeremy S; Lertmemongkolchai, Ganjana

PglB function and glycosylation efficiency is temperature dependent when the pgl locus is integrated in the Escherichia coli chromosome. (2022) Terra, Vanessa S; Mauri, Marta; Sannasiddappa, Thippeswamy H; Smith, Alexander A; Stevens, Mark P; Grant, Andrew J; Wren, Brendan W; Cuccui, Jon; Glycoengineering of Veterinary Vaccines consortium (GoVV)

2021

The X-ray structure of L-threonine dehydrogenase from the common hospital pathogen Clostridium difficile. (2021) Adjogatse, Eyram; Bennett, Josh; Guo, Jingxu; Erskine, Peter T; Wood, Steve P; Wren, Brendan W; Cooper, Jonathan B

Complete genome for Actinobacillus pleuropneumoniae serovar 8 reference strain 405: comparative analysis with draft genomes for different laboratory stock cultures indicates little genetic variation. (2021) Bossé, Janine T; Li, Yanwen; Cohen, Liza Miriam; Stegger, Marc; Angen, Øystein; Lacouture, Sonia; Gottschalk, Marcelo; Lei, Liancheng; Koene, Miriam; Kuhnert, Peter; Bandara, Aloka B; Inzana, Thomas J; Holden, Matthew TG; Harris, David; Oshota, Olusegun; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; On Behalf Of The BRaDP T Consortium

Rationally designed mariner vectors for functional genomic analysis of Actinobacillus pleuropneumoniae and other Pasteurellaceae species by transposon-directed insertion-site sequencing (TraDIS). (2021) Bossé, Janine T; Li, Yanwen; Leanse, Leon G; Zhou, Liqing; Chaudhuri, Roy R; Peters, Sarah E; Wang, Jinhong; Maglennon, Gareth A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile. (2021) Dawson, Lisa F; Peltier, Johann; Hall, Catherine L; Harrison, Mark A; Derakhshan, Maria; Shaw, Helen A; Fairweather, Neil F; Wren, Brendan W

Revisiting Campylobacter jejuni Virulence and Fitness Factors: Role in Sensing, Adapting, and Competing. (2021) Elmi, Abdi; Nasher, Fauzy; Dorrell, Nick; Wren, Brendan; Gundogdu, Ozan

Probing Differences in Gene Essentiality Between the Human and Animal Adapted Lineages of the Mycobacterium tuberculosis Complex Using TnSeq. (2021) Gibson, Amanda J; Passmore, Ian J; Faulkner, Valwynne; Xia, Dong; Nobeli, Irene; Stiens, Jennifer; Willcocks, Sam; Clark, Taane G; Sobkowiak, Ben; Werling, Dirk; Villarreal-Ramos, Bernardo; Wren, Brendan W; Kendall, Sharon L

Production of p-cresol by Decarboxylation of p-HPA by All Five Lineages of Clostridioides difficile Provides a Growth Advantage. Harrison, Mark A; Kaur, Harparkash; Wren, Brendan W; Dawson, Lisa F

Sequential Vaccination With Heterologous Acinetobacter baumannii Strains Induces Broadly Reactive Antibody Responses. (2021) Kamuyu, Gathoni; Suen Cheng, Yat; Willcocks, Sam; Kewcharoenwong, Chidchamai; Kiratisin, Pattarachai; Taylor, Peter W; Wren, Brendan W; Lertmemongkolchai, Ganjana; Stabler, Richard A; Brown, Jeremy

Use of Precision-Cut Tissue Slices as a Translational Model to Study Host-Pathogen Interaction. (2021) Majorova, Dominika; Atkins, Elizabeth; Martineau, Henny; Vokral, Ivan; Oosterhuis, Dorenda; Olinga, Peter; Wren, Brendan; Cuccui, Jon; Werling, Dirk

Multivalent poultry vaccine development using Protein Glycan Coupling Technology. (2021) Mauri, Marta; Sannasiddappa, Thippeswamy H; Vohra, Prerna; Corona-Torres, Ricardo; Smith, Alexander A; Chintoan-Uta, Cosmin; Bremner, Abi; Terra, Vanessa S; Abouelhadid, Sherif; Stevens, Mark P; Grant, Andrew J; Cuccui, Jon; Wren, Brendan W; Glycoengineering of Veterinary Vaccines Consortium

Profiling of Haemophilus influenzae strain R2866 with carbohydrate-based covalent probes. (2021) Metier, Camille; Dow, Jennifer; Wootton, Hayley; Lynham, Steven; Wren, Brendan; Wagner, Gerd K

MdaB and NfrA, Two Novel Reductases Important in the Survival and Persistence of the Major Enteropathogen Campylobacter jejuni. (2021) Nasher, Fauzy; Taylor, Aidan J; Elmi, Abdi; Lehri, Burhan; Ijaz, Umer Z; Baker, Dave; Goram, Richard; Lynham, Steven; Singh, Dipali; Stabler, Richard; Kelly, David J; Gundogdu, Ozan; Wren, Brendan W

Development of an automated platform for the optimal production of glycoconjugate vaccines expressed in Escherichia coli. (2021) Samaras, Jasmin J; Mauri, Marta; Kay, Emily J; Wren, Brendan W; Micheletti, Martina

Evaluation of a Campylobacter jejuni N-glycan-ExoA glycoconjugate vaccine to reduce C. jejuni colonisation in chickens. (2021) Vohra, Prerna; Chintoan-Uta, Cosmin; Bremner, Abi; Mauri, Marta; Terra, Vanessa S; Cuccui, Jon; Wren, Brendan W; Vervelde, Lonneke; Stevens, Mark P; Glycoengineering of Veterinary Vaccines Consortium

2020

Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance. (2020) Abouelhadid, Sherif; Raynes, John; Bui, Tam; Cuccui, Jon; Wren, Brendan W

Draft Genome Sequences of the Type Strains of Actinobacillus indolicus (46K2C) and Actinobacillus porcinus (NM319), Two NAD-Dependent Bacterial Species Found in the Respiratory Tract of Pigs. (2020) Bossé, Janine T; Li, Yanwen; Fernandez Crespo, Roberto; Angen, Øystein; Holden, Matthew TG; Weinert, Lucy A; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

Serovar-dependent differences in Hfq-regulated phenotypes in Actinobacillus pleuropneumoniae. (2020) Crispim, Josicelli Souza; da Silva, Thyara Ferreira; Sanches, Newton Moreno; da Silva, Giarlã Cunha; Pereira, Monalessa Fábia; Rossi, Ciro César; Li, Yanwen; Terra, Vanessa Sofia; Vohra, Prerna; Wren, Brendan W; Langford, Paul R; Bossé, Janine T; Bazzolli, Denise Mara Soares

Improving protein glycan coupling technology (PGCT) for glycoconjugate vaccine production. (2020) Dow, Jennifer Mhairi; Mauri, Marta; Scott, Timothy Alexander; Wren, Brendan William

Generation and Evaluation of a Glaesserella (Haemophilus) parasuis Capsular Mutant. (2020) Eberle, Kirsten C; Hau, Samantha J; Luan, Shi-Lu; Weinert, Lucy A; Stasko, Judith A; Wang, Jinhong; Peters, Sarah E; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W; Brockmeier, Susan L

Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits. (2020) Faulkner, Valwynne; Cox, Adrienne Adele; Goh, Shan; van Bohemen, Annelies; Gibson, Amanda J; Liebster, Oliver; Wren, Brendan W; Willcocks, Sam; Kendall, Sharon L

Microbe Profile: Campylobacter jejuni - survival instincts. (2020) Gundogdu, Ozan; Wren, Brendan W

Investigating novel vaccine candidates for Clostridium difficile. (2020) Hall, C

Clostridioides difficile para-Cresol Production Is Induced by the Precursor para-Hydroxyphenylacetate. (2020) Harrison, Mark A; Faulds-Pain, Alexandra; Kaur, Harparkash; Dupuy, Bruno; Henriques, Adriano O; Martin-Verstraete, Isabelle; Wren, Brendan W; Dawson, Lisa F

Clostridioides difficile para-Cresol Production Is Induced by the Precursor para-Hydroxyphenylacetate. (2020) Harrison, Mark A; Faulds-Pain, Alexandra; Kaur, Harparkash; Dupuy, Bruno; Henriques, Adriano O; Martin-Verstraete, Isabelle; Wren, Brendan W; Dawson, Lisa F

Evaluation of the recombinant proteins RlpB and VacJ as a vaccine for protection against Glaesserella parasuis in pigs. (2020) Hau, Samantha J; Luan, Shi-Lu; Loving, Crystal L; Nicholson, Tracy L; Wang, Jinhong; Peters, Sarah E; Seilly, David; Weinert, Lucy A; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W; Brockmeier, Susan L; BRaDP1T Consortium

Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter. (2020) McKenna, Aaron; Ijaz, Umer Zeeshan; Kelly, Carmel; Linton, Mark; Sloan, William T; Green, Brian D; Lavery, Ursula; Dorrell, Nick; Wren, Brendan W; Richmond, Anne; Corcionivoschi, Nicolae; Gundogdu, Ozan

Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter. (2020) McKenna, Aaron; Ijaz, Umer Zeeshan; Kelly, Carmel; Linton, Mark; Sloan, William T; Green, Brian D; Lavery, Ursula; Dorrell, Nick; Wren, Brendan W; Richmond, Anne; Corcionivoschi, Nicolae; Gundogdu, Ozan

Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce <i>Campylobacter</i>. (2020) McKenna, Aaron; Ijaz, Umer Zeeshan; Kelly, Carmel; Linton, Mark; Sloan, William; Green, Brian; Lavery, Ursula; Dorrell, Nick; Wren, Brendan; Richmond, Anne; Corcionivoschi, Nicolae; Gundogdu, Ozan

The Antimicrobial Peptide, Bactenecin 5, Supports Cell-Mediated but Not Humoral Immunity in the Context of a Mycobacterial Antigen Vaccine Model. (2020) Munshi, Tulika; Sparrow, Adam; Wren, Brendan W; Reljic, Rajko; Willcocks, Samuel J

Ferric Citrate Regulator FecR Is Translocated across the Bacterial Inner Membrane via a Unique Twin-Arginine Transport-Dependent Mechanism. (2020) Passmore, Ian J; Dow, Jennifer M; Coll, Francesc; Cuccui, Jon; Palmer, Tracy; Wren, Brendan W

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43. (2020) Terra, Vanessa S; Plumptre, Charles D; Wall, Emma C; Brown, Jeremy S; Wren, Brendan W

Construction of a pneumolysin deficient mutant in streptococcus pneumoniae serotype 1 strain 519/43 and phenotypic characterisation. (2020) Terra, Vanessa S; Plumptre, Charles D; Wall, Emma C; Brown, Jeremy S; Wren, Brendan W

Evaluation of Glycosylated FlpA and SodB as Subunit Vaccines Against Campylobacter jejuni Colonisation in Chickens. (2020) Vohra, Prerna; Chintoan-Uta, Cosmin; Terra, Vanessa S; Bremner, Abi; Cuccui, Jon; Wren, Brendan W; Vervelde, Lonneke; Stevens, Mark P

CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With Streptococcus pneumoniae Meningitis. (2020) Wall, Emma C; Brownridge, Philip; Laing, Gavin; Terra, Vanessa S; Mlozowa, Veronica; Denis, Brigitte; Nyirenda, Mulinda; Allain, Theresa; Ramos-Sevillano, Elisa; Carrol, Enitan; Collins, Andrea; Gordon, Stephen B; Lalloo, David G; Wren, Brendan; Beynon, Robert; Heyderman, Robert S; Brown, Jeremy S

Revisiting aminocoumarins for the treatment of melioidosis. (2020) Willcocks, SJ; Cia, F; Francisco, AF; Wren, BW

Virulence of the emerging pathogen, Burkholderia pseudomallei, depends upon the O-linked oligosaccharyltransferase, PglL. (2020) Willcocks, Samuel J; Denman, Carmen; Cia, Felipe; McCarthy, Elizabeth; Cuccui, Jon; Wren, Brendan W

2019

Quantitative Analyses Reveal Novel Roles for N-Glycosylation in a Major Enteric Bacterial Pathogen. (2019) Abouelhadid, Sherif; North, Simon J; Hitchen, Paul; Vohra, Prerna; Chintoan-Uta, Cosmin; Stevens, Mark; Dell, Anne; Cuccui, Jon; Wren, Brendan W

Sodium Taurocholate Stimulates Campylobacter jejuni Outer Membrane Vesicle Production via Down-Regulation of the Maintenance of Lipid Asymmetry Pathway. (2019) Davies, Cadi; Taylor, Aidan J; Elmi, Abdi; Winter, Jody; Liaw, Janie; Grabowska, Anna D; Gundogdu, Ozan; Wren, Brendan W; Kelly, David J; Dorrell, Nick

Environmental interactions are regulated by temperature in Burkholderia seminalis TC3.4.2R3. (2019) Gonçalves, Priscila Jane Romano de Oliveira; Hume, Carmen C Denman; Ferreira, Almir José; Tsui, Sarina; Brocchi, Marcelo; Wren, Brendan W; Araujo, Welington Luiz

Recent advances in the production of recombinant glycoconjugate vaccines. (2019) Kay, Emily; Cuccui, Jon; Wren, Brendan W

Adaptation of host transmission cycle during Clostridium difficile speciation. (2019) Kumar, Nitin; Browne, Hilary P; Viciani, Elisa; Forster, Samuel C; Clare, Simon; Harcourt, Katherine; Stares, Mark D; Dougan, Gordon; Fairley, Derek J; Roberts, Paul; Pirmohamed, Munir; Clokie, Martha RJ; Jensen, Mie Birgitte Frid; Hargreaves, Katherine R; Ip, Margaret; Wieler, Lothar H; Seyboldt, Christian; Norén, Torbjörn; Riley, Thomas V; Kuijper, Ed J; Wren, Brendan W; Lawley, Trevor D

The Campylobacter jejuni Type VI Secretion System Enhances the Oxidative Stress Response and Host Colonization. (2019) Liaw, Janie; Hong, Geunhye; Davies, Cadi; Elmi, Abdi; Sima, Filip; Stratakos, Alexandros; Stef, Lavinia; Pet, Ioan; Hachani, Abderrahman; Corcionivoschi, Nicolae; Wren, Brendan W; Gundogdu, Ozan; Dorrell, Nick

Clostridium perfringens epsilon toxin vaccine candidate lacking toxicity to cells expressing myelin and lymphocyte protein. (2019) Morcrette, Helen; Bokori-Brown, Monika; Ong, Stephanie; Bennett, Leo; Wren, Brendan W; Lewis, Nick; Titball, Richard W

Transmission of multidrug-resistant Campylobacter jejuni to children from different sources in Pakistan. (2019) Noreen, Zobia; Siddiqui, Fariha; Javed, Sundus; Wren, Brendan W; Bokhari, Habib

Domestication of Campylobacter jejuni NCTC 11168. (2019) Pascoe, Ben; Williams, Lisa K; Calland, Jessica K; Meric, Guillaume; Hitchings, Matthew D; Dyer, Myles; Ryder, Joseph; Shaw, Sophie; Lopes, Bruno S; Chintoan-Uta, Cosmin; Allan, Elaine; Vidal, Ana; Fearnley, Catherine; Everest, Paul; Pachebat, Justin A; Cogan, Tristan A; Stevens, Mark P; Humphrey, Thomas J; Wilkinson, Thomas S; Cody, Alison J; Colles, Frances M; Jolley, Keith A; Maiden, Martin CJ; Strachan, Norval; Pearson, Bruce M; Linton, Dennis; Wren, Brendan W; Parkhill, Julian; Kelly, David J; van Vliet, Arnoud HM; Forbes, Ken J; Sheppard, Samuel K

Cytoplasmic glycoengineering of Apx toxin fragments in the development of Actinobacillus pleuropneumoniae glycoconjugate vaccines. (2019) Passmore, Ian J; Andrejeva, Anna; Wren, Brendan W; Cuccui, Jon

In vitro and in vivo properties of the bovine antimicrobial peptide, Bactenecin 5. (2019) Price, RL; Bugeon, L; Mostowy, S; Makendi, C; Wren, BW; Williams, HD; Willcocks, SJ

The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics. (2019) Shaw, HA; Preston, MD; Vendrik, KEW; Cairns, MD; Browne, HP; Stabler, RA; Crobach, MJT; Corver, J; Pituch, H; Ingebretsen, A; Pirmohamed, M; Faulds-Pain, A; Valiente, E; Lawley, TD; Fairweather, NF; Kuijper, EJ; Wren, BW

Clostridium difficile clade 3 (RT023) have a modified cell surface and contain a large transposable island with novel cargo. (2019) Shaw, Helen Alexandra; Khodadoost, Ladan; Preston, Mark D; Corver, Jeroen; Mullany, Peter; Wren, Brendan W

In vitro and in vivo characterisation of Listeria monocytogenes outbreak isolates. (2019) Stratakos, Alexandros Ch; Ijaz, Umer Zeeshan; Ward, Patrick; Linton, Mark; Kelly, Carmel; Pinkerton, Laurette; Scates, Pam; McBride, Jane; Pet, Ioan; Criste, Adriana; Stef, Ducu; Couto, Jillian M; Sloan, William T; Dorrell, Nick; Wren, Brendan W; Stef, Lavinia; Gundogdu, Ozan; Corcionivoschi, Nicolae

Publisher Correction: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2019) Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Van Vinh Chau, Nguyen; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium

Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales. (2019) Wileman, Thomas M; Weinert, Lucy A; Howell, Kate J; Wang, Jinhong; Peters, Sarah E; Williamson, Susanna M; Wells, Jerry M; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W

Genome-wide assessment of antimicrobial tolerance in Yersinia pseudotuberculosis under ciprofloxacin stress. (2019) Willcocks, Samuel; Huse, Kristin K; Stabler, Richard; Oyston, Petra CF; Scott, Andrew; Atkins, Helen S; Wren, Brendan W

Type III secretion system confers enhanced virulence in clinical non-O1/non-O139 Vibrio cholerae. (2019) Zeb, Samia; Shah, Muhammad Ali; Yasir, Muhammad; Awan, Hassaan Mehboob; Prommeenate, Peerada; Klanchui, Amornpan; Wren, Brendan W; Thomson, Nicholas; Bokhari, Habib

2018

Proposal of serovars 17 and 18 of Actinobacillus pleuropneumoniae based on serological and genotypic analysis. (2018) Bossé, JT; LI, Y; Sárközi, R; Fodor, L; Lacouture, S; Gottschalk, M; Amoribieta, MC; Angen, Ø; Nedbalcova, K; Holden, MT; Wren, B

Comparative sequence analysis of the capsular polysaccharide loci of Actinobacillus pleuropneumoniae serovars 1-18, and development of two multiplex PCRs for comprehensive capsule typing. (2018) Bossé, Janine T; Li, Yanwen; Fernandez Crespo, Roberto; Lacouture, Sonia; Gottschalk, Marcelo; Sárközi, Rita; Fodor, László; Casas Amoribieta, Maria; Angen, Øystein; Nedbalcova, Katerina; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

Proposal of serovars 17 and 18 of Actinobacillus pleuropneumoniae based on serological and genotypic analysis. (2018) Bossé, Janine T; Li, Yanwen; Sárközi, Rita; Fodor, László; Lacouture, Sonia; Gottschalk, Marcelo; Casas Amoribieta, Maria; Angen, Øystein; Nedbalcova, Katerina; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

Development of anaerobic culturing methods to study the evolution and transmission of the human intestinal microbiota. (2018) Browne, HP

Molecular epidemiological and pathogenesis studies of Streptococcus pneumoniae serotype 1 strains from West Africa. (2018) Ebruke, CN

The Streptococcos suis sortases SrtB and SrtF are essential for disease in pigs. (2018) Faulds-Pain, Alexandra; Shaw, Helen Alexandra; Terra, Vanessa Sofia; Kellner, Steven; Brockmeier, Susan L; Wren, Brendan W

Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine. (2018) Herbert, Jenny A; Kay, Emily J; Faustini, Sian E; Richter, Alex; Abouelhadid, Sherif; Cuccui, Jon; Wren, Brendan; Mitchell, Timothy J

Comprehensive Longitudinal Microbiome Analysis of the Chicken Cecum Reveals a Shift From Competitive to Environmental Drivers and a Window of Opportunity for Campylobacter. (2018) Ijaz, Umer Zeeshan; Sivaloganathan, Lojika; McKenna, Aaron; Richmond, Anne; Kelly, Carmel; Linton, Mark; Stratakos, Alexandros Ch; Lavery, Ursula; Elmi, Abdi; Wren, Brendan W; Dorrell, Nick; Corcionivoschi, Nicolae; Gundogdu, Ozan

Comprehensive longitudinal microbiome analysis of the chicken cecum reveals a shift from competitive to environmental drivers and a window of opportunity for <i>Campylobacter</i>. (2018) Ijaz, Umer Zeeshan; Sivaloganathan, Lojika; Mckenna, Aaron; Richmond, Anne; Kelly, Carmel; Linton, Mark; Stratakos, Alexandros; Lavery, Ursula; Elmi, Abdi; Wren, Brendan; Dorrell, Nick; Corcionivoschi, Nicolae; Gundogdu, Ozan

Functional analysis of the Helicobacter pullorum N-linked protein glycosylation system. (2018) Jervis, Adrian J; Wood, Alison G; Cain, Joel A; Butler, Jonathan A; Frost, Helen; Lord, Elizabeth; Langdon, Rebecca; Cordwell, Stuart J; Wren, Brendan W; Linton, Dennis

An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia. (2018) Marshall, Laura E; Nelson, Michelle; Davies, Carwyn H; Whelan, Adam O; Jenner, Dominic C; Moule, Madeleine G; Denman, Carmen; Cuccui, Jon; Atkins, Timothy P; Wren, Brendan W; Prior, Joann L

Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria. (2018) Passmore, Ian J; Letertre, Marine PM; Preston, Mark D; Bianconi, Irene; Harrison, Mark A; Nasher, Fauzy; Kaur, Harparkash; Hong, Huynh A; Baines, Simon D; Cutting, Simon M; Swann, Jonathan R; Wren, Brendan W; Dawson, Lisa F

Inactivation of bpsl1039-1040 ATP-binding cassette transporter reduces intracellular survival in macrophages, biofilm formation and virulence in the murine model of Burkholderia pseudomallei infection. (2018) Pinweha, Peechanika; Pumirat, Pornpan; Cuccui, Jon; Jitprasutwit, Niramol; Muangsombut, Veerachat; Srinon, Varintip; Boonyuen, Usa; Thiennimitr, Parameth; Vattanaviboon, Paiboon; Cia, Felipe; Willcocks, Sam; Bancroft, Gregory J; Wren, Brendan W; Korbsrisate, Sunee

A recombinant conjugated pneumococcal vaccine that protects against murine infections with a similar efficacy to Prevnar-13. (2018) Reglinski, Mark; Ercoli, Giuseppe; Plumptre, Charlie; Kay, Emily; Petersen, Fernanda C; Paton, James C; Wren, Brendan W; Brown, Jeremy S

The S-layer protein of a Clostridium difficile SLCT-11 strain displays a complex glycan required for normal cell growth and morphology. (2018) Richards, Emma; Bouché, Laura; Panico, Maria; Arbeloa, Ana; Vinogradov, Evgeny; Morris, Howard; Wren, Brendan; Logan, Susan M; Dell, Anne; Fairweather, Neil F

Exploring the oxidative, antimicrobial and genomic properties of Campylobacter jejuni strains isolated from poultry. (2018) Ugarte-Ruiz, Maria; Domínguez, Lucas; Corcionivoschi, Nicolae; Wren, Brendan W; Dorrell, Nick; Gundogdu, Ozan

Vibrio cholerae accessory colonisation factor AcfC: a chemotactic protein with a role in hyperinfectivity. (2018) Valiente, Esmeralda; Davies, Cadi; Mills, Dominic C; Getino, Maria; Ritchie, Jennifer M; Wren, Brendan W

High-throughput analysis of Yersinia pseudotuberculosis gene essentiality in optimised in vitro conditions, and implications for the speciation of Yersinia pestis. (2018) Willcocks, Samuel J; Stabler, Richard A; Atkins, Helen S; Oyston, Petra F; Wren, Brendan W

Structure-activity relationships in a new class of non-substrate-like covalent inhibitors of the bacterial glycosyltransferase LgtC. (2018) Xu, Yong; Cuccui, Jon; Denman, Carmen; Maharjan, Tripty; Wren, Brendan W; Wagner, Gerd K

2017

The importance of the glycosylation of antimicrobial peptides: natural and synthetic approaches. (2017) Bednarska, Natalia G; Wren, Brendan W; Willcocks, Sam J

Galleria mellonella is low cost and suitable surrogate host for studying virulence of human pathogenic Vibrio cholerae. (2017) Bokhari, Habib; Ali, Amjad; Noreen, Zobia; Thomson, Nicholas; Wren, Brendan W

Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae. (2017) Bossé, Janine T; Li, Yanwen; Rogers, Jon; Fernandez Crespo, Roberto; Li, Yinghui; Chaudhuri, Roy R; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R

Comparative Genomic Analysis and In Vivo Modeling of Streptococcus pneumoniae ST3081 and ST618 Isolates Reveal Key Genetic and Phenotypic Differences Contributing to Clonal Replacement of Serotype 1 in The Gambia. (2017) Bricio-Moreno, Laura; Ebruke, Chinelo; Chaguza, Chrispin; Cornick, Jennifer; Kwambana-Adams, Brenda; Yang, Marie; Mackenzie, Grant; Wren, Brendan W; Everett, Dean; Antonio, Martin; Kadioglu, Aras

Use of Proteins Identified through a Functional Genomic Screen To Develop a Protein Subunit Vaccine That Provides Significant Protection against Virulent Streptococcus suis in Pigs. (2017) Brockmeier, Susan L; Loving, Crystal L; Nicholson, Tracy L; Wang, Jinhong; Peters, Sarah E; Weinert, Lucy; Chaudhuri, Roy; Seilly, David J; Langford, Paul R; Rycroft, Andrew; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W

Correction for Cairns et al., "Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages". (2017) Cairns, MD; Preston, MD; Hall, CL; Gerding, DN; Hawkey, PM; Kato, H; Kim, H; Kuijper, EJ; Lawley, TD; Pituch, H; Reid, S; Kullin, B; Riley, TV; Solomon, K; Tsai, PJ; Weese, JS; Stabler, RA; Wren, BW

The bile salt sodium taurocholate induces Campylobacter jejuni outer membrane vesicle production and increases OMV-associated proteolytic activity. (2017) Elmi, Abdi; Dorey, Amber; Watson, Eleanor; Jagatia, Heena; Inglis, Neil F; Gundogdu, Ozan; Bajaj-Elliott, Mona; Wren, Brendan W; Smith, David GE; Dorrell, Nick

Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014. (2017) Hernandez-Garcia, Juan; Wang, Jinhong; Restif, Olivier; Holmes, Mark A; Mather, Alison E; Weinert, Lucy A; Wileman, Thomas M; Thomson, Jill R; Langford, Paul R; Wren, Brendan W; Rycroft, Andrew; Maskell, Duncan J; Tucker, Alexander W; BRADP1T Consortium

"Pathotyping" Multiplex PCR Assay for Haemophilus parasuis: a Tool for Prediction of Virulence. (2017) Howell, Kate J; Weinert, Lucy A; Peters, Sarah E; Wang, Jinhong; Hernandez-Garcia, Juan; Chaudhuri, Roy R; Luan, Shi-Lu; Angen, Øystein; Aragon, Virginia; Williamson, Susanna M; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W

The In Vitro and In Vivo Effect of Carvacrol in Preventing Campylobacter Infection, Colonization and in Improving Productivity of Chicken Broilers. (2017) Kelly, C; Gundogdu, O; Pircalabioru, G; Cean, A; Scates, P; Linton, M; Pinkerton, L; Magowan, E; Stef, L; Simiz, E; Pet, I; Stewart, S; Stabler, R; Wren, B; Dorrell, N; Corcionivoschi, N

Zoonotic Transfer of Clostridium difficile Harboring Antimicrobial Resistance between Farm Animals and Humans. (2017) Knetsch, CW; Kumar, N; Forster, SC; Connor, TR; Browne, HP; Harmanus, C; Sanders, IM; Harris, SR; Turner, L; Morris, T; Perry, M; Miyajima, F; Roberts, P; Pirmohamed, M; Songer, JG; Weese, JS; Indra, A; Corver, J; Rupnik, M; Wren, BW; Riley, TV; Kuijper, EJ; Lawley, TD

Draft Genome Sequence of Campylobacter jejuni 11168H. (2017) Macdonald, Sarah E; Gundogdu, Ozan; Dorrell, Nick; Wren, Brendan W; Blake, Damer; Stabler, Richard

Disparate subcellular location of putative sortase substrates in Clostridium difficile. (2017) Peltier, Johann; Shaw, Helen A; Wren, Brendan W; Fairweather, Neil F

2016

All Yersinia enterocolitica are pathogenic: virulence of phylogroup 1 Y. enterocolitica in a Galleria mellonella infection model. (2016) Alenizi, Dhahi; Ringwood, Tamara; Redhwan, Alya; Bouraha, Bouchra; Wren, Brendan W; Prentice, Michael; McNally, Alan

YPTB3816 of Yersinia pseudotuberculosis strain IP32953 is a virulence-related metallo-oligopeptidase. (2016) Atas, Ali; Seddon, Alan M; Ford, Donna C; Cooper, Ian A; Wren, Brendan W; Oyston, Petra CF; Karlyshev, Andrey V

Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae. (2016) Bossé, Janine T; Chaudhuri, Roy R; Li, Yanwen; Leanse, Leon G; Fernandez Crespo, Roberto; Coupland, Paul; Holden, Matthew TG; Bazzolli, Denise M; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R

ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae. (2016) Bossé, Janine T; Li, Yanwen; Fernandez Crespo, Roberto; Chaudhuri, Roy R; Rogers, Jon; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; the BRaDP1T Consortium

The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans. (2016) Bouché, Laura; Panico, Maria; Hitchen, Paul; Binet, Daniel; Sastre, Federico; Faulds-Pain, Alexandra; Valiente, Esmeralda; Vinogradov, Evgeny; Aubry, Annie; Fulton, Kelly; Twine, Susan; Logan, Susan M; Wren, Brendan W; Dell, Anne; Morris, Howard R

Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages. (2016) Cairns, MD; Preston, MD; Hall, CL; Gerding, DN; Hawkey, PM; Kato, H; Kim, H; Kuijper, EJ; Lawley, TD; Pituch, H; Reid, S; Kullin, B; Riley, TV; Solomon, K; Tsai, PJ; Weese, JS; Stabler, RA; Wren, BW

The N-linking glycosylation system from Actinobacillus pleuropneumoniae is required for adhesion and has potential use in glycoengineering. (2016) Cuccui, Jon; Terra, Vanessa S; Bossé, Janine T; Naegeli, Andreas; Abouelhadid, Sherif; Li, Yanwen; Lin, Chia-Wei; Vohra, Prerna; Tucker, Alexander W; Rycroft, Andrew N; Maskell, Duncan J; Aebi, Markus; Langford, Paul R; Wren, Brendan W; BRaDP1T Consortium

The Campylobacter jejuni Oxidative Stress Regulator RrpB Is Associated with a Genomic Hypervariable Region and Altered Oxidative Stress Resistance. (2016) Gundogdu, Ozan; da Silva, Daiani T; Mohammad, Banaz; Elmi, Abdi; Wren, Brendan W; van Vliet, Arnoud HM; Dorrell, Nick

Recombinant expression of Streptococcus pneumoniae capsular polysaccharides in Escherichia coli. (2016) Kay, Emily J; Yates, Laura E; Terra, Vanessa S; Cuccui, Jon; Wren, Brendan W

Phenotypic and genotypic characterization of enteroaggregative Escherichia coli isolates from pediatric population in Pakistan. (2016) Khalil, Uzma; Younus, Mahwish; Asghar, Naeem; Siddiqui, Fariha; Gómez-Duarte, Oscar G; Wren, Brendan W; Bokhari, Habib

Actinobacillus pleuropneumoniae serovar 8 predominates in England and Wales. (2016) Li, Y; Bossé, JT; Williamson, SM; Maskell, DJ; Tucker, AW; Wren, BW; Rycroft, AN; Langford, PR; BRADP1T Consortium

The phylogenetic and phenotypic analysis of Salmonella enterica serovar Weltevreden. (2016) Makendi Njock, EC

A Phylogenetic and Phenotypic Analysis of Salmonella enterica Serovar Weltevreden, an Emerging Agent of Diarrheal Disease in Tropical Regions. (2016) Makendi, Carine; Page, Andrew J; Wren, Brendan W; Le Thi Phuong, Tu; Clare, Simon; Hale, Christine; Goulding, David; Klemm, Elizabeth J; Pickard, Derek; Okoro, Chinyere; Hunt, Martin; Thompson, Corinne N; Phu Huong Lan, Nguyen; Tran Do Hoang, Nhu; Thwaites, Guy E; Le Hello, Simon; Brisabois, Anne; Weill, François-Xavier; Baker, Stephen; Dougan, Gordon

'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution. (2016) McNally, Alan; Thomson, Nicholas R; Reuter, Sandra; Wren, Brendan W

Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences. (2016) Mottram, Lynda; Speak, Anneliese O; Selek, Reza M; Cambridge, Emma L; McIntyre, Zoe; Kane, Leanne; Mukhopadhyay, Subhankar; Grove, Carolyn; Colin, Amy; Brandt, Cordelia; Duque-Correa, Maria A; Forbester, Jessica; Nguyen, Tu Anh Pham; Hale, Christine; Vasilliou, George S; Arends, Mark J; Wren, Brendan W; Dougan, Gordon; Clare, Simon

Draft Genome Sequence of Robinsoniella peoriensis 6600698, a Confounder of Clostridium difficile Diagnosis. (2016) Roberts, Chrissy H; Shaw, Helen Alexandra; Ferguson, Natalie; Holland, Mark; Wren, Brendan W; Stabler, Richard A

The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications. (2016) Thi Khanh Nhu, Nguyen; Riordan, David W; Do Hoang Nhu, Tran; Thanh, Duy Pham; Thwaites, Guy; Huong Lan, Nguyen Phu; Wren, Brendan W; Baker, Stephen; Stabler, Richard A

Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation. (2016) Valiente, Esmeralda; Bouché, Laura; Hitchen, Paul; Faulds-Pain, Alexandra; Songane, Mario; Dawson, Lisa F; Donahue, Elizabeth; Stabler, Richard A; Panico, Maria; Morris, Howard R; Bajaj-Elliott, Mona; Logan, Susan M; Dell, Anne; Wren, Brendan W

Intracellular replication of the well-armed pathogen Burkholderia pseudomallei. (2016) Willcocks, Sam J; Denman, Carmen C; Atkins, Helen S; Wren, Brendan W

Characterization of enteropathogenic Escherichia coli of clinical origin from the pediatric population in Pakistan. (2016) Younas, Mahwish; Siddiqui, Fariha; Noreen, Zobia; Bokhari, Syeda Sadia; Gomez-Duarte, Oscar G; Wren, Brendan W; Bokhari, Habib

2015

Whole genome investigation of a divergent clade of the pathogen Streptococcus suis. (2015) Baig, Abiyad; Weinert, Lucy A; Peters, Sarah E; Howell, Kate J; Chaudhuri, Roy R; Wang, Jinhong; Holden, Matthew TG; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J

Corrigendum to ‘Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae’ [Veterinary Microbiology 178 (2015) 279–282]. (2015) Bossé, Janine T; Li, Yanwen; Atherton, Tom G; Walker, Stephanie; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R

Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae. (2015) Bossé, Janine T; Li, Yanwen; Atherton, Tom G; Walker, Stephanie; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae. (2015) Bossé, Janine T; Li, Yanwen; Walker, Stephanie; Atherton, Tom; Fernandez Crespo, Roberto; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Oshota, Olusegun; Holden, Matt TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T Consortium

Genomic Epidemiology of a Protracted Hospital Outbreak Caused by a Toxin A-Negative Clostridium difficile Sublineage PCR Ribotype 017 Strain in London, England. (2015) Cairns, MD; Preston, MD; Lawley, TD; Clark, TG; Stabler, RA; Wren, BW

Virulence characteristics of hcp (+) Campylobacter jejuni and Campylobacter coli isolates from retail chicken. (2015) Corcionivoschi, Nicolae; Gundogdu, Ozan; Moran, Lynn; Kelly, Carmel; Scates, Pam; Stef, Lavinia; Cean, Ada; Wren, Brendan; Dorrell, Nick; Madden, Robert H

Investigating the roles of the cell wall anchoring sortase enzyme and sorted proteins in Clostridium difficile. (2015) Donahue, EH

Temporal changes in nasopharyngeal carriage of Streptococcus pneumoniae serotype 1 genotypes in healthy Gambians before and after the 7-valent pneumococcal conjugate vaccine. (2015) Ebruke, Chinelo; Roca, Anna; Egere, Uzochukwu; Darboe, Ousainou; Hill, Philip C; Greenwood, Brian; Wren, Brendan W; Adegbola, Richard A; Antonio, Martin

Campylobacter jejuni outer membrane vesicle-associated proteolytic activity promotes bacterial invasion by mediating cleavage of intestinal epithelial cell E-cadherin and occludin. (2015) Elmi, Abdi; Nasher, Fauzy; Jagatia, Heena; Gundogdu, Ozan; Bajaj-Elliott, Mona; Wren, Brendan; Dorrell, Nick

The Campylobacter jejuni MarR-like transcriptional regulators RrpA and RrpB both influence bacterial responses to oxidative and aerobic stresses. (2015) Gundogdu, Ozan; da Silva, Daiani T; Mohammad, Banaz; Elmi, Abdi; Mills, Dominic C; Wren, Brendan W; Dorrell, Nick

Development of a Multiplex PCR Assay for Rapid Molecular Serotyping of Haemophilus parasuis. (2015) Howell, Kate J; Peters, Sarah E; Wang, Jinhong; Hernandez-Garcia, Juan; Weinert, Lucy A; Luan, Shi-Lu; Chaudhuri, Roy R; Angen, Øystein; Aragon, Virginia; Williamson, Susanna M; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W; BRaDP1T Consortium

Chromosomal integration vectors allowing flexible expression of foreign genes in Campylobacter jejuni. (2015) Jervis, Adrian J; Butler, Jonathan A; Wren, Brendan W; Linton, Dennis

Pancreatic amylase is an environmental signal for regulation of biofilm formation and host interaction in Campylobacter jejuni. (2015) Jowiya, Waheed; Brunner, Katja; Abouelhadid, Sherif; Hussain, Haitham A; Nair, Sean P; Sadiq, Sohaib; Williams, Lisa K; Trantham, Emma K; Stephenson, Holly; Wren, Brendan W; Bajaj-Elliott, Mona; Cogan, Tristan A; Laws, Andrew P; Wade, Jim; Dorrell, Nick; Allan, Elaine

Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence. (2015) Kumar, Nitin; Miyajima, Fabio; He, Miao; Roberts, Paul; Swale, Andrew; Ellison, Louise; Pickard, Derek; Smith, Godfrey; Molyneux, Rebecca; Dougan, Gordon; Parkhill, Julian; Wren, Brendan W; Parry, Christopher M; Pirmohamed, Munir; Lawley, Trevor D

The characterization of the lipoprotein VacJ in Burkholderia pseudomallei and Burkholderia thailandensis. (2015) Lim, J

Functional analysis of N-linking oligosaccharyl transferase enzymes encoded by deep-sea vent proteobacteria. (2015) Mills, Dominic C; Jervis, Adrian J; Abouelhadid, Sherif; Yates, Laura E; Cuccui, Jon; Linton, Dennis; Wren, Brendan W

Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei. (2015) Moule, Madeleine G; Spink, Natasha; Willcocks, Sam; Lim, Jiali; Guerra-Assunção, José Afonso; Cia, Felipe; Champion, Olivia L; Senior, Nicola J; Atkins, Helen S; Clark, Taane; Bancroft, Gregory J; Cuccui, Jon; Wren, Brendan W

Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage. (2015) Peltier, Johann; Shaw, Helen A; Couchman, Edward C; Dawson, Lisa F; Yu, Lu; Choudhary, Jyoti S; Kaever, Volkhard; Wren, Brendan W; Fairweather, Neil F

Molecular detection identified a type six secretion system in Campylobacter jejuni from various sources but not from human cases. (2015) Siddiqui, F; Champion, O; Akram, M; Studholme, D; Eqani, SAMAS; Wren, BW; Titball, R; Bokhari, H

Draft Genome Sequence of the Enteropathogenic Bacterium Campylobacter jejuni Strain cj255. (2015) Siddiqui, Fariha Masood; Ibrahim, Muhammad; Noureen, Nighat; Noreen, Zobia; Titball, Richard W; Champion, Olivia L; Wren, Brendan W; Studholme, David; Bokhari, Habib

Erratum: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2015) Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Chau, Nguyen Van Vinh; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium

Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2015) Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Van Vinh Chau, Nguyen; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium

2014

December 2014 - Ebola, food poisoning, and a look back through the year. (2014) UNSPECIFIED

Multiplex PCR assay for unequivocal differentiation of Actinobacillus pleuropneumoniae serovars 1 to 3, 5 to 8, 10, and 12. (2014) Bossé, Janine T; Li, Yanwen; Angen, Øystein; Weinert, Lucy A; Chaudhuri, Roy R; Holden, Matthew T; Williamson, Susanna M; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

The generation of successive unmarked mutations and chromosomal insertion of heterologous genes in Actinobacillus pleuropneumoniae using natural transformation. (2014) Bossé, Janine T; Soares-Bazzolli, Denise M; Li, Yanwen; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J; Rycroft, Andrew N; Langford, Paul R; BRaDP1T Consortium

Hijacking bacterial glycosylation for the production of glycoconjugates, from vaccines to humanised glycoproteins. (2014) Cuccui, Jon; Wren, Brendan

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. (2014) Donahue, Elizabeth H; Dawson, Lisa F; Valiente, Esmeralda; Firth-Clark, Stuart; Major, Meriel R; Littler, Eddy; Perrior, Trevor R; Wren, Brendan W

The post-translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence. (2014) Faulds-Pain, Alexandra; Twine, Susan M; Vinogradov, Evgeny; Strong, Philippa CR; Dell, Anne; Buckley, Anthony M; Douce, Gillian R; Valiente, Esmeralda; Logan, Susan M; Wren, Brendan W

The importance of the magnesium transporter MgtB for virulence of Yersinia pseudotuberculosis and Yersinia pestis. (2014) Ford, Donna C; Joshua, George WP; Wren, Brendan W; Oyston, Petra CF

Genetic Mechanisms Involved in Campylobacter jejuni Survival Under Oxidative Stress Conditions. (2014) Gundogdu, O; Wren, BW; Dorrell, N

Surveillance and diagnosis of plague and anthrax in Tanzania and Zambia. (2014) Hang'ombe, BM; Ziwa, M; Haule, M; Nakamura, I; Samui, KL; Kaile, D; Mweene, AS; Kilonzo, BS; Lyamuya, EF; Matee, M; Sugimoto, C; Sawa, H; Wren, BW

Identification of possible virulence marker from Campylobacter jejuni isolates. (2014) Harrison, James W; Dung, Tran Thi Ngoc; Siddiqui, Fariha; Korbrisate, Sunee; Bukhari, Habib; Tra, My Phan Vu; Hoang, Nguyen Van Minh; Carrique-Mas, Juan; Bryant, Juliet; Campbell, James I; Studholme, David J; Wren, Brendan W; Baker, Stephen; Titball, Richard W; Champion, Olivia L

Host immunity to Clostridium difficile PCR ribotype 017 strains. (2014) Jafari, Nazila V; Songane, Mario; Stabler, Richard A; Elawad, Mamoun; Wren, Brendan W; Allan, Elaine; Bajaj-Elliott, Mona

Genome-wide evaluation of the interplay between Caenorhabditis elegans and Yersinia pseudotuberculosis during in vivo biofilm formation. (2014) Joshua, George WP; Atkinson, Steve; Goldstone, Robert J; Patrick, Hannah L; Stabler, Richard A; Purves, Joanne; Cámara, Miguel; Williams, Paul; Wren, Brendan W

Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation. (2014) Karlyshev, AV; Thacker, G; Jones, MA; Clements, MO; Wren, BW

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. (2014) Moule, Madeleine G; Hemsley, Claudia M; Seet, Qihui; Guerra-Assunção, José Afonso; Lim, Jiali; Sarkar-Tyson, Mitali; Clark, Taane G; Tan, Patrick BO; Titball, Richard W; Cuccui, Jon; Wren, Brendan W

Galleria mellonella is an effective model to study Actinobacillus pleuropneumoniae infection. (2014) Pereira, Monalessa Fábia; Rossi, Ciro César; Vieira de Queiroz, Marisa; Martins, Gustavo Ferreira; Isaac, Clement; Bossé, Janine T; Li, Yanwen; Wren, Brendan W; Terra, Vanessa Sofia; Cuccui, Jon; Langford, Paul R; Bazzolli, Denise Mara Soares

Parallel independent evolution of pathogenicity within the genus Yersinia. (2014) Reuter, Sandra; Connor, Thomas R; Barquist, Lars; Walker, Danielle; Feltwell, Theresa; Harris, Simon R; Fookes, Maria; Hall, Miquette E; Petty, Nicola K; Fuchs, Thilo M; Corander, Jukka; Dufour, Muriel; Ringwood, Tamara; Savin, Cyril; Bouchier, Christiane; Martin, Liliane; Miettinen, Minna; Shubin, Mikhail; Riehm, Julia M; Laukkanen-Ninios, Riikka; Sihvonen, Leila M; Siitonen, Anja; Skurnik, Mikael; Falcão, Juliana Pfrimer; Fukushima, Hiroshi; Scholz, Holger C; Prentice, Michael B; Wren, Brendan W; Parkhill, Julian; Carniel, Elisabeth; Achtman, Mark; McNally, Alan; Thomson, Nicholas R

Pseudaminic acid on Campylobacter jejuni flagella modulates dendritic cell IL-10 expression via Siglec-10 receptor: a novel flagellin-host interaction. (2014) Stephenson, Holly N; Mills, Dominic C; Jones, Hannah; Milioris, Enea; Copland, Alastair; Dorrell, Nick; Wren, Brendan W; Crocker, Paul R; Escors, David; Bajaj-Elliott, Mona

Prevalence of Type VI Secretion System in Spanish Campylobacter jejuni Isolates. (2014) Ugarte-Ruiz, M; Stabler, RA; Domínguez, L; Porrero, MC; Wren, BW; Dorrell, N; Gundogdu, O

The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move. (2014) Valiente, E; Cairns, MD; Wren, BW

Shared characteristics between Mycobacterium tuberculosis and fungi contribute to virulence. (2014) Willcocks, Sam; Wren, Brendan W

Biological roles of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. (2014) van Alphen, Lieke B; Wenzel, Cory Q; Richards, Michele R; Fodor, Christopher; Ashmus, Roger A; Stahl, Martin; Karlyshev, Andrey V; Wren, Brendan W; Stintzi, Alain; Miller, William G; Lowary, Todd L; Szymanski, Christine M

2013

THE ROLE OF MLTD AND RPON IN H. PYLORI BIOFILM FORMATION IN VITRO. (2013) Alhaj-Hussein, BT; Kazakos, EI; Wren, BW; Dorrell, N

Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli. (2013) Birchenough, George MH; Johansson, Malin EV; Stabler, Richard A; Dalgakiran, Fatma; Hansson, Gunnar C; Wren, Brendan W; Luzio, J Paul; Taylor, Peter W

Escherichia coli pathotypes in Pakistan from consecutive floods in 2010 and 2011. (2013) Bokhari, Habib; Shah, Muhammad Ali; Asad, Saba; Akhtar, Sania; Akram, Muhammad; Wren, Brendan W

Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis. (2013) Cuccui, Jon; Thomas, Rebecca M; Moule, Madeleine G; D'Elia, Riccardo V; Laws, Thomas R; Mills, Dominic C; Williamson, Diane; Atkins, Timothy P; Prior, Joann L; Wren, Brendan W

Bacteria like sharing their sweets. (2013) Cuccui, Jon; Wren, Brendan W

Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores. (2013) Dembek, Marcin; Stabler, Richard A; Witney, Adam A; Wren, Brendan W; Fairweather, Neil F

Population biology of Streptococcus pneumoniae in West Africa: multilocus sequence typing of serotypes that exhibit different predisposition to invasive disease and carriage. (2013) Donkor, Eric S; Adegbola, Richard A; Wren, Brendan W; Antonio, Martin

Campylobacter jejuni outer membrane vesicles possess proteolytic activity and enhance bacterial adhesion to and invasion of intestinal epithelial cells. (2013) Elmi, A; Naz, N; Gundogdu, O; Wren, BW; Dorrell, N

Improved bacterial mutagenesis by high-frequency allele exchange, demonstrated in Clostridium difficile and Streptococcus suis. (2013) Faulds-Pain, Alexandra; Wren, Brendan W

Variation in the distribution of the MarR-type transcriptional regulators Cj1546 and Cj1556 amongst Campylobacter jejuni strains correlates with differences in resistance to oxidative and aerobic stress. (2013) Gundogdu, O; Mohammed, B; Teixeira, DDS; Elmi, A; Wren, BW; Dorrell, N

Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease. (2013) Hargreaves, Chantal E; Grasso, Marco; Hampe, Christiane S; Stenkova, Anna; Atkinson, Steve; Joshua, George WP; Wren, Brendan W; Buckle, Ashley M; Dunn-Walters, Deborah; Banga, J Paul

Gene content and diversity of the loci encoding biosynthesis of capsular polysaccharides of the 15 serovar reference strains of Haemophilus parasuis. (2013) Howell, Kate J; Weinert, Lucy A; Luan, Shi-Lu; Peters, Sarah E; Chaudhuri, Roy R; Harris, David; Angen, Oystein; Aragon, Virginia; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium

Unusual features in organisation of capsular polysaccharide-related genes of C. jejuni strain X. (2013) Karlyshev, AV; Quail, MA; Parkhill, J; Wren, BW

Growth inhibition of pathogenic bacteria by sulfonylurea herbicides. (2013) Kreisberg, Jason F; Ong, Nicholas T; Krishna, Aishwarya; Joseph, Thomas L; Wang, Jing; Ong, Catherine; Ooi, Hui Ann; Sung, Julie C; Siew, Chern Chiang; Chang, Grace C; Biot, Fabrice; Cuccui, Jon; Wren, Brendan W; Chan, Joey; Sivalingam, Suppiah P; Zhang, Lian-Hui; Verma, Chandra; Tan, Patrick

Understanding and managing zoonotic risk in the new livestock industries. (2013) Liverani, Marco; Waage, Jeff; Barnett, Tony; Pfeiffer, Dirk U; Rushton, Jonathan; Rudge, James W; Loevinsohn, Michael E; Scoones, Ian; Smith, Richard D; Cooper, Ben S; White, Lisa J; Goh, Shan; Horby, Peter; Wren, Brendan; Gundogdu, Ozan; Woods, Abigail; Coker, Richard J

Generation of a Tn5 transposon library in Haemophilus parasuis and analysis by transposon-directed insertion-site sequencing (TraDIS). (2013) Luan, Shi-Lu; Chaudhuri, Roy R; Peters, Sarah E; Mayho, Matthew; Weinert, Lucy A; Crowther, Sarah A; Wang, Jinhong; Langford, Paul R; Rycroft, Andrew; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium

Transposon mutagenesis in Mycoplasma hyopneumoniae using a novel mariner-based system for generating random mutations. (2013) Maglennon, Gareth A; Cook, Beth S; Deeney, Alannah S; Bossé, Janine T; Peters, Sarah E; Langford, Paul R; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; BRaDP1T consortium

Development of a self-replicating plasmid system for Mycoplasma hyopneumoniae. (2013) Maglennon, Gareth A; Cook, Beth S; Matthews, Dominic; Deeney, Alannah S; Bossé, Janine T; Langford, Paul R; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; BRaDP1T consortium

The agr locus regulates virulence and colonization genes in Clostridium difficile 027. (2013) Martin, Melissa J; Clare, Simon; Goulding, David; Faulds-Pain, Alexandra; Barquist, Lars; Browne, Hilary P; Pettit, Laura; Dougan, Gordon; Lawley, Trevor D; Wren, Brendan W

Reinvestigation into the mechanisms of Campylobacter jejuni invasion of intestinal epithelial cells. (2013) Naz, N; Taylor, E; Gundogdu, O; Elmi, A; Wren, BW; Dorrell, N

Enteric bacterial invasion of intestinal epithelial cells in vitro is dramatically enhanced using a vertical diffusion chamber model. (2013) Naz, Neveda; Mills, Dominic C; Wren, Brendan W; Dorrell, Nick

Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays. (2013) Stabler, Richard A; Larsson, Jonas T; Al-Jaberi, Suaad; Nielsen, Eva M; Kay, Emily; Tam, Clarence C; Higgins, Craig D; Rodrigues, Laura C; Richardson, Judith F; O'Brien, Sarah J; Wren, Brendan W

Campylobacter jejuni lipooligosaccharide sialylation, phosphorylation, and amide/ester linkage modifications fine-tune human Toll-like receptor 4 activation. (2013) Stephenson, Holly N; John, Constance M; Naz, Neveda; Gundogdu, Ozan; Dorrell, Nick; Wren, Brendan W; Jarvis, Gary A; Bajaj-Elliott, Mona

Gene function hypotheses for the Campylobacter jejuni glycome generated by a logic-based approach. (2013) Sternberg, Michael JE; Tamaddoni-Nezhad, Alireza; Lesk, Victor I; Kay, Emily; Hitchen, Paul G; Cootes, Adrian; van Alphen, Lieke B; Lamoureux, Marc P; Jarrell, Harold C; Rawlings, Christopher J; Soo, Evelyn C; Szymanski, Christine M; Dell, Anne; Wren, Brendan W; Muggleton, Stephen H

Identification of Type VI secretion system (T6SS) in Spanish Campylobacter jejuni. (2013) Ugarte-Ruiz, M; Gundogdu, O; Wassenaar, T; Ancochea, C; Porrero, MC; Wren, BW; Dorrell, N; Dominguez, L

The twin arginine translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis. (2013) Wagley, Sariqa; Hemsley, Claudia; Thomas, Rachael; Moule, Madeleine G; Vanaporn, Muthita; Andreae, Clio; Robinson, Matthew; Goldman, Stan; Wren, Brendan W; Butler, Clive S; Titball, Richard W

2012

The continually evolving Clostridium difficile species. (2012) Cairns, Michelle D; Stabler, Richard A; Shetty, Nandini; Wren, Brendan W

Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region. (2012) Cuccui, Jon; Milne, Timothy S; Harmer, Nicholas; George, Alison J; Harding, Sarah V; Dean, Rachel E; Scott, Andrew E; Sarkar-Tyson, Mitali; Wren, Brendan W; Titball, Richard W; Prior, Joann L

Characterisation of Clostridium difficile biofilm formation, a role for Spo0A. (2012) Dawson, Lisa F; Valiente, Esmeralda; Faulds-Pain, Alexandra; Donahue, Elizabeth H; Wren, Brendan W

The Clostridium difficile spo0A gene is a persistence and transmission factor. (2012) Deakin, Laura J; Clare, Simon; Fagan, Robert P; Dawson, Lisa F; Pickard, Derek J; West, Michael R; Wren, Brendan W; Fairweather, Neil F; Dougan, Gordon; Lawley, Trevor D

Comparative phylogenomics of Streptococcus pneumoniae isolated from invasive disease and nasopharyngeal carriage from West Africans. (2012) Donkor, Eric S; Stabler, Richard A; Hinds, Jason; Adegbola, Richard A; Antonio, Martin; Wren, Brendan W

Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. (2012) Elmi, Abdi; Watson, Eleanor; Sandu, Pamela; Gundogdu, Ozan; Mills, Dominic C; Inglis, Neil F; Manson, Erin; Imrie, Lisa; Bajaj-Elliott, Mona; Wren, Brendan W; Smith, David GE; Dorrell, Nick

Evidence of Yersinia pestis DNA from fleas in an endemic plague area of Zambia. (2012) Hang'ombe, Bernard M; Nakamura, Ichiro; Samui, Kenny L; Kaile, Davy; Mweene, Aaron S; Kilonzo, Bukheti S; Sawa, Hirofumi; Sugimoto, Chihiro; Wren, Brendan W

Identification of the plague reservoir in an endemic area of Zambia. (2012) Hang’ombe, Bernard M; Nakamura, I; Kaile, D; Mweene, AS; Samui, KL; Kilonzo, BS; Sawa, H; Sugimoto, C; Wren, B

Emergence and global spread of epidemic healthcare-associated Clostridium difficile. (2012) He, Miao; Miyajima, Fabio; Roberts, Paul; Ellison, Louise; Pickard, Derek J; Martin, Melissa J; Connor, Thomas R; Harris, Simon R; Fairley, Derek; Bamford, Kathleen B; D'Arc, Stephanie; Brazier, Jon; Brown, Derek; Coia, John E; Douce, Gill; Gerding, Dale; Kim, Hee Jung; Koh, Tse Hsien; Kato, Haru; Senoh, Mitsutoshi; Louie, Tom; Michell, Stephen; Butt, Emma; Peacock, Sharon J; Brown, Nick M; Riley, Tom; Songer, Glen; Wilcox, Mark; Pirmohamed, Munir; Kuijper, Ed; Hawkey, Peter; Wren, Brendan W; Dougan, Gordon; Parkhill, Julian; Lawley, Trevor D

Characterization of the structurally diverse N-linked glycans of Campylobacter species. (2012) Jervis, Adrian J; Butler, Jonathan A; Lawson, Andrew J; Langdon, Rebecca; Wren, Brendan W; Linton, Dennis

Phenotypic and genotypic characterizations of Campylobacter jejuni isolated from the broiler meat production process. (2012) Kudirkienė, Eglė; Cohn, Marianne Thorup; Stabler, Richard A; Strong, Philippa CR; Sernienė, Loreta; Wren, Brendan W; Nielsen, Eva Møller; Malakauskas, Mindaugas; Brøndsted, Lone

Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment. (2012) Mills, Dominic C; Gundogdu, Ozan; Elmi, Abdi; Bajaj-Elliott, Mona; Taylor, Peter W; Wren, Brendan W; Dorrell, Nick

Identification of immunogenic and virulence-associated Campylobacter jejuni proteins. (2012) Nielsen, Lene N; Luijkx, Thomas A; Vegge, Christina S; Johnsen, Christina Kofoed; Nuijten, Piet; Wren, Brendan W; Ingmer, Hanne; Krogfelt, Karen A

Cellular response of Campylobacter jejuni to trisodium phosphate. (2012) Riedel, Charlotte Tandrup; Cohn, Marianne Thorup; Stabler, Richard A; Wren, Brendan; Brøndsted, Lone

Neutrophil extracellular traps exhibit antibacterial activity against burkholderia pseudomallei and are influenced by bacterial and host factors. (2012) Riyapa, Donporn; Buddhisa, Surachat; Korbsrisate, Sunee; Cuccui, Jon; Wren, Brendan W; Stevens, Mark P; Ato, Manabu; Lertmemongkolchai, Ganjana

Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations. (2012) Stabler, Richard A; Dawson, Lisa F; Valiente, Esmeralda; Cairns, Michelle D; Martin, Melissa J; Donahue, Elizabeth H; Riley, Thomas V; Songer, J Glenn; Kuijper, Ed J; Dingle, Kate E; Wren, Brendan W

Recent developments in bacterial protein glycan coupling technology and glycoconjugate vaccine design. (2012) Terra, Vanessa S; Mills, Dominic C; Yates, Laura E; Abouelhadid, Sherif; Cuccui, Jon; Wren, Brendan W

2011

Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. (2011) Atkinson, Steve; Goldstone, Robert J; Joshua, George WP; Chang, Chien-Yi; Patrick, Hannah L; Cámara, Miguel; Wren, Brendan W; Williams, Paul

The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains. (2011) Dawson, Lisa F; Donahue, Elizabeth H; Cartman, Stephen T; Barton, Richard H; Bundy, Jake; McNerney, Ruth; Minton, Nigel P; Wren, Brendan W

Hypervirulent Clostridium difficile PCR-ribotypes exhibit resistance to widely used disinfectants. (2011) Dawson, Lisa F; Valiente, Esmeralda; Donahue, Elizabeth H; Birchenough, George; Wren, Brendan W

Clinical Issues and Molecular Characterisation of Salmonella Typhi Isolates from South East Asia. (2011) Dolecek, C

High levels of recombination among Streptococcus pneumoniae isolates from the Gambia. (2011) Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP

High Levels of Recombination among Streptococcus pneumoniae Isolates from the Gambia - corrections to earlier article. (2011) Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP

High Levels of Recombination among Streptococcus pneumoniae Isolates from the Gambia. (2011) Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP

The Campylobacter jejuni transcriptional regulator Cj1556 plays a role in the oxidative and aerobic stress response and is important for bacterial survival in vivo. (2011) Gundogdu, Ozan; Mills, Dominic C; Elmi, Abdi; Martin, Melissa J; Wren, Brendan W; Dorrell, Nick

Genomic variations define divergence of water/wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes. (2011) Hepworth, Philip J; Ashelford, Kevin E; Hinds, Jason; Gould, Katherine A; Witney, Adam A; Williams, Nicola J; Leatherbarrow, Howard; French, Nigel P; Birtles, Richard J; Mendonca, Chriselle; Dorrell, Nick; Wren, Brendan W; Wigley, Paul; Hall, Neil; Winstanley, Craig

Post-genome Analysis of the Foodborne Pathogen Campylobacter jejuni. (2011) Kay, E; Gundogdu, O; Wren, B

Effect of chicken meat environment on gene expression of Campylobacter jejuni and its relevance to survival in food. (2011) Ligowska, Małgorzata; Cohn, Marianne Thorup; Stabler, Richard A; Wren, Brendan W; Brøndsted, Lone

Bacterial epidemiology and biology--lessons from genome sequencing. (2011) Parkhill, Julian; Wren, Brendan W

The Campylobacter jejuni NCTC11168 capsule prevents excessive cytokine production by dendritic cells. (2011) Rose, Anna; Kay, Emily; Wren, Brendan W; Dallman, Margaret J

Identification and characterisation of a novel adhesin Ifp in Yersinia pseudotuberculosis. (2011) Strong, Philippa CR; Hinchliffe, Stewart J; Patrick, Hannah; Atkinson, Steve; Champion, Olivia L; Wren, Brendan W

Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage. (2011) Valiente, Esmeralda; Dawson, Lisa F; Cairns, Michelle D; Stabler, Richard A; Wren, Brendan W

BμG@Sbase--a microbial gene expression and comparative genomic database. (2011) Witney, Adam A; Waldron, Denise E; Brooks, Lucy A; Tyler, Richard H; Withers, Michael; Stoker, Neil G; Wren, Brendan W; Butcher, Philip D; Hinds, Jason

2010

Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity. (2010) Champion, Olivia L; Karlyshev, Andrey V; Senior, Nicola J; Woodward, Martin; La Ragione, Roberto; Howard, Sarah L; Wren, Brendan W; Titball, Richard W

Yersinia pseudotuberculosis mntH functions in intracellular manganese accumulation, which is essential for virulence and survival in cells expressing functional Nramp1. (2010) Champion, Olivia L; Karlyshev, Andrey; Cooper, Ian AM; Ford, Donna C; Wren, Brendan W; Duffield, Melanie; Oyston, Petra CF; Titball, Richard W

Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge. (2010) Commander, Nicola J; Brewer, James M; Wren, Brendan W; Spencer, Stephen A; Macmillan, Alastair P; Stack, Judith A

Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection. (2010) Edwards, Lindsey A; Nistala, Kiran; Mills, Dominic C; Stephenson, Holly N; Zilbauer, Matthias; Wren, Brendan W; Dorrell, Nick; Lindley, Keith J; Wedderburn, Lucy R; Bajaj-Elliott, Mona

Evolutionary dynamics of Clostridium difficile over short and long time scales. (2010) He, Miao; Sebaihia, Mohammed; Lawley, Trevor D; Stabler, Richard A; Dawson, Lisa F; Martin, Melissa J; Holt, Kathryn E; Seth-Smith, Helena MB; Quail, Michael A; Rance, Richard; Brooks, Karen; Churcher, Carol; Harris, David; Bentley, Stephen D; Burrows, Christine; Clark, Louise; Corton, Craig; Murray, Vicky; Rose, Graham; Thurston, Scott; van Tonder, Andries; Walker, Danielle; Wren, Brendan W; Dougan, Gordon; Parkhill, Julian

Glycoproteomics: a powerful tool for characterizing the diverse glycoforms of bacterial pilins and flagellins. (2010) Hitchen, Paul G; Twigger, Katie; Valiente, Esmeralda; Langdon, Rebecca H; Wren, Brendan W; Dell, Anne

Characterization of N-linked protein glycosylation in Helicobacter pullorum. (2010) Jervis, Adrian J; Langdon, Rebecca; Hitchen, Paul; Lawson, Andrew J; Wood, Alison; Fothergill, Joanne L; Morris, Howard R; Dell, Anne; Wren, Brendan; Linton, Dennis

Systems analysis of bacterial glycomes. (2010) Kay, Emily; Lesk, Victor I; Tamaddoni-Nezhad, Alireza; Hitchen, Paul G; Dell, Anne; Sternberg, Michael J; Muggleton, Stephen; Wren, Brendan W

The sudden dominance of blaCTX-M harbouring plasmids in Shigella spp. Circulating in Southern Vietnam. (2010) Nguyen, Nhu Thi Khanh; Ha, Vinh; Tran, Nga Vu Thieu; Stabler, Richard; Pham, Duy Thanh; Le, Thi Minh Vien; van Doorn, H Rogier; Cerdeño-Tárraga, Ana; Thomson, Nicholas; Campbell, James; Nguyen, Van Minh Hoang; Tran, Thi Thu Nga; Pham, Minh Van; Cao, Thuy Thu; Wren, Brendan; Farrar, Jeremy; Baker, Stephen

Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. (2010) Pumirat, Pornpan; Cuccui, Jon; Stabler, Richard A; Stevens, Joanne M; Muangsombut, Veerachat; Singsuksawat, Ekapot; Stevens, Mark P; Wren, Brendan W; Korbsrisate, Sunee

Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching. (2010) Snyder, Lori AS; Loman, Nicholas J; Linton, James D; Langdon, Rebecca R; Weinstock, George M; Wren, Brendan W; Pallen, Mark J

In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions. (2010) Stabler, Richard A; Valiente, Esmeralda; Dawson, Lisa F; He, Miao; Parkhill, Julian; Wren, Brendan W

Clostridium difficile using DNA microarrays. (2010) Stabler, Richard; Dawson, Lisa; Wren, Brendan

Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1. (2010) Zelmer, Andrea; Martin, Melissa J; Gundogdu, Ozan; Birchenough, George; Lever, Rebecca; Wren, Brendan W; Luzio, J Paul; Taylor, Peter W

2009

Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis. (2009) Champion, Olivia L; Cooper, Ian AM; James, Sarah L; Ford, Donna; Karlyshev, Andrey; Wren, Brendan W; Duffield, Melanie; Oyston, Petra CF; Titball, Richard W

Campylobacter jejuni cocultured with epithelial cells reduces surface capsular polysaccharide expression. (2009) Corcionivoschi, N; Clyne, M; Lyons, A; Elmi, A; Gundogdu, O; Wren, BW; Dorrell, N; Karlyshev, AV; Bourke, B

Comparative genomics of Clostridium difficile. (2009) Dawson, LF; Stabler, RA; Wren, BW

Clostridium difficile--a continually evolving and problematic pathogen. (2009) Dawson, Lisa F; Valiente, Esmeralda; Wren, Brendan W

The Three Bears and Virulence-Associated Plasmids in the Genus Yersinia. (2009) Howard, SL; Strong, PC; Wren, BW

Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. (2009) Howard, Sarah L; Jagannathan, Aparna; Soo, Evelyn C; Hui, Joseph PM; Aubry, Annie J; Ahmed, Imran; Karlyshev, Andrey; Kelly, John F; Jones, Michael A; Stevens, Mark P; Logan, Susan M; Wren, Brendan W

Recent advances in systems microbiology. (2009) Kay, Emily; Wren, Brendan W

N-linked glycosylation in bacteria: an unexpected application. (2009) Langdon, Rebecca H; Cuccui, Jon; Wren, Brendan W

Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. (2009) Lawley, Trevor D; Clare, Simon; Walker, Alan W; Goulding, David; Stabler, Richard A; Croucher, Nicholas; Mastroeni, Piero; Scott, Paul; Raisen, Claire; Mottram, Lynda; Fairweather, Neil F; Wren, Brendan W; Parkhill, Julian; Dougan, Gordon

Genome sequence of the emerging pathogen Helicobacter canadensis. (2009) Loman, NJ; Snyder, LAS; Linton, JD; Langdon, R; Lawson, AJ; Weinstock, GM; Wren, BW; Pallen, MJ

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. (2009) Stabler, Richard A; He, Miao; Dawson, Lisa; Martin, Melissa; Valiente, Esmeralda; Corton, Craig; Lawley, Trevor D; Sebaihia, Mohammed; Quail, Michael A; Rose, Graham; Gerding, Dale N; Gibert, Maryse; Popoff, Michel R; Parkhill, Julian; Dougan, Gordon; Wren, Brendan W

Steps toward broad-spectrum therapeutics: discovering virulence-associated genes present in diverse human pathogens. (2009) Stubben, Chris J; Duffield, Melanie L; Cooper, Ian A; Ford, Donna C; Gans, Jason D; Karlyshev, Andrey V; Lingard, Bryan; Oyston, Petra CF; de Rochefort, Anna; Song, Jian; Wren, Brendan W; Titball, Rick W; Wolinsky, Murray

New levels of sophistication in the transcriptional landscape of bacteria. (2009) van Vliet, Arnoud Hm; Wren, Brendan W

2008

YtxR acts as an overriding transcriptional off switch for the Yersinia enterocolitica Ysc-Yop type 3 secretion system. (2008) Axler-DiPerte, Grace L; Hinchliffe, Stewart J; Wren, Brendan W; Darwin, Andrew J

Comparative genomics of Campylobacter jejuni. (2008) Champion, O; Al-Jaberi, S; Stabler, R; Wren, B

Assessing the role of p-cresol tolerance in Clostridium difficile. (2008) Dawson, Lisa F; Stabler, Richard A; Wren, Brendan W

Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress. (2008) Emerson, Jenny E; Stabler, Richard A; Wren, Brendan W; Fairweather, Neil F

Role of the Cj1371 periplasmic protein and the Cj0355c two-component regulator in the Campylobacter jejuni NCTC 11168 response to oxidative stress caused by paraquat. (2008) Garénaux, Amélie; Guillou, Sandrine; Ermel, Gwennola; Wren, Brendan; Federighi, Michel; Ritz, Magali

Evolution of Pathogen Yersinia. (2008) Hinchliffe, SJ; Strong, PCR; Howard, SL; Wren, BW

The importance of the Rcs phosphorelay in the survival and pathogenesis of the enteropathogenic yersiniae. (2008) Hinchliffe, Stewart J; Howard, Sarah L; Huang, Yahui H; Clarke, David J; Wren, Brendan W

Campylobacter jejuni capsule polysaccharide. (2008) Karlyshev, A; Wren, B; Moran, A

Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. (2008) Stabler, Richard A; Dawson, Lisa F; Oyston, Petra CF; Titball, Richard W; Wade, Jim; Hinds, Jason; Witney, Adam A; Wren, Brendan W

Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences. (2008) Stabler, Richard A; Dawson, Lisa F; Phua, Leslie TH; Wren, Brendan W

Burkholderia pseudomallei: animal models of infection. (2008) Titball, Richard W; Russell, Paul; Cuccui, Jon; Easton, Anna; Haque, Ashraful; Atkins, Tim; Sarkar-Tyson, Mitali; Harley, Vicki; Wren, Brendan; Bancroft, Gregory J

Campylobacter jejuni-mediated disease pathogenesis: an update. (2008) Zilbauer, Matthias; Dorrell, Nick; Wren, Brendan W; Bajaj-Elliott, Mona

2007

The RovA regulons of Yersinia enterocolitica and Yersinia pestis are distinct: evidence that many RovA-regulated genes were acquired more recently than the core genome. (2007) Cathelyn, Jason S; Ellison, Damon W; Hinchliffe, Stewart J; Wren, Brendan W; Miller, Virginia L

The identification of two protective DNA vaccines from a panel of five plasmid constructs encoding Brucella melitensis 16M genes. (2007) Commander, Nicola J; Spencer, Stephen A; Wren, Brendan W; MacMillan, Alastair P

Alteration in bacterial capsular polysaccharides following co-culture with human epithelial cells. (2007) Corcionivoschi, N; Clyne, M; Lyons, A; Lamoureux, M; Wren, B; Dorell, N; Karlyshev, A; Szymanski, C; Bourke, B

The second century of Campylobacter research: recent advances, new opportunities and old problems. (2007) Dorrell, Nick; Wren, Brendan W

Investigation of the role of two Campylobacter jejuni glycoproteins during bacterial interactions with human intestinal epithelial cells. (2007) Elmi, AD; Zilbauer, M; Bajaj-Elliott, M; Wren, B; Dorrell, N

Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome and functional characterisation of selected genes involved in strain pathogenesis. (2007) Gundogdu, O; Martin, MJ; Bentley, SD; Holden, MT; Parkhill, J; Wren, BW; Dorrell, N

Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence. (2007) Gundogdu, Ozan; Bentley, Stephen D; Holden, Matt T; Parkhill, Julian; Dorrell, Nick; Wren, Brendan W

Evolution of Pathogenic Yersinia. (2007) Hinchliffe, S; Strong, P; Howard, S; Wren, B

Functional characterisation of the Campylobacter jejuni NCTC11168H flagellin glycosylation island in the avian host. (2007) Jagannathan, A; Howard, S; Stevens, MP; Jones, MA; Wren, BW

Deletion of a previously uncharacterized flagellar-hook-length control gene fliK modulates the sigma54-dependent regulon in Campylobacter jejuni. (2007) Kamal, Nahid; Dorrell, Nick; Jagannathan, Aparna; Turner, Susan M; Constantinidou, Chrystala; Studholme, David J; Marsden, Gemma; Hinds, Jason; Laing, Ken G; Wren, Brendan W; Penn, Charles W

Genetics and properties of a novel capsule produced by untypable strain X of C-jejuni. (2007) Karlyshev, A; Quail, MA; Stevens, K; Elmi, A; Parkhill, J; Wren, BW

Campylobacter proteases and their role in colonisation and stress responses. (2007) Karlyshev, A; Thacker, G; Jones, MA; Clements, MO; Wren, BW

Characterisation of the Campylobacter jejuni major antigenic protein PEB3. (2007) Langdon, RH; Linton, D; Hinchliffe, S; Cawthraw, S; Newell, D; Wren, B

Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. (2007) McNally, David J; Lamoureux, Marc P; Karlyshev, Andrey V; Fiori, Laura M; Li, Jianjun; Thacker, Gillian; Coleman, Russell A; Khieu, Nam H; Wren, Brendan W; Brisson, Jean-Robert; Jarrell, Harold C; Szymanski, Christine M

Bacterial pathogenomics. (2007) Pallen, Mark J; Wren, Brendan W

Comparative genome analyses of the pathogenic Yersiniae based on the genome sequence of Yersinia enterocolitica strain 8081. (2007) Thomson, Nicholas R; Howard, Sarah; Wren, Brendan W; Prentice, Michael B

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in mediating host bactericidal activity against Campylobacter jejuni. (2007) Zilbauer, M; Dorrell, N; Elmi, A; Lindley, K; Klein, N; Nunez, G; Wren, B; Bajaj-Elliott, M

A major role for intestinal epithelial nucleotide oligomerization domain (NOD) protein NOD1 in mediating host bactericidal activity against Campylobacter jejuni. (2007) Zilbauer, M; Dorrell, N; Elmi, A; Nunez, G; Klein, NJ; Wren, BW; Bajaj-Elliott, M

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. (2007) Zilbauer, Matthias; Dorrell, Nick; Elmi, Abdi; Lindley, Keith J; Schüller, Stephanie; Jones, Hannah E; Klein, Nigel J; Núnez, Gabriel; Wren, Brendan W; Bajaj-Elliott, Mona

A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. (2007) Zilbauer, Matthias; Dorrell, Nick; Elmi, Abdi; Lindley, Keith J; Schüller, Stephanie; Jones, Hannah E; Klein, Nigel J; Núňez, Gabriel; Wren, Brendan W; Bajaj-Elliott, Mona

2006

Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. (2006) Cuccui, J; Easton, A; Chu, KK; Bancroft, GJ; Oyston, PCF; Titball, RW; Wren, BW

Serotype differences and lack of biofilm formation characterize Yersinia pseudotuberculosis infection of the Xenopsylla cheopis flea vector of Yersinia pestis. (2006) Erickson, David L; Jarrett, Clayton O; Wren, Brendan W; Hinnebusch, B Joseph

Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori. (2006) Hatzifoti, Caterina; Roussel, Yvonne; Harris, Andrew G; Wren, Brendan W; Morrow, John W; Bajaj-Elliott, Mona

Application of comparative phylogenomics to study the evolution of Yersinia enterocolitica and to identify genetic differences relating to pathogenicity. (2006) Howard, Sarah L; Gaunt, Michael W; Hinds, Jason; Witney, Adam A; Stabler, Richard; Wren, Brendan W

Biofilm formation in Campylobacter jejuni. (2006) Joshua, GWP; Guthrie-Irons, C; Karlyshev, AV; Wren, BW

Where molecular pathogenesis and NMR spectroscopy collide: An integrated approach towards the development of it CPS-based therapy for Campylobacter jejuni. (2006) McNally, DJ; Jarrell, HC; Lamoureux, M; Coleman, RA; Karlyshev, AV; Wren, BW; Brisson, JR; Szymanski, CM

Numerical analysis of DNA microarray data of Campylobacter jejuni strains correlated with survival, cytolethal distending toxin and haemolysin analyses. (2006) On, Stephen LW; Dorrell, Nick; Petersen, Lise; Bang, Dang D; Morris, Samantha; Forsythe, Stephen J; Wren, Brendan W

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. (2006) Sebaihia, Mohammed; Wren, Brendan W; Mullany, Peter; Fairweather, Neil F; Minton, Nigel; Stabler, Richard; Thomson, Nicholas R; Roberts, Adam P; Cerdeño-Tárraga, Ana M; Wang, Hongmei; Holden, Matthew TG; Wright, Anne; Churcher, Carol; Quail, Michael A; Baker, Stephen; Bason, Nathalie; Brooks, Karen; Chillingworth, Tracey; Cronin, Ann; Davis, Paul; Dowd, Linda; Fraser, Audrey; Feltwell, Theresa; Hance, Zahra; Holroyd, Simon; Jagels, Kay; Moule, Sharon; Mungall, Karen; Price, Claire; Rabbinowitsch, Ester; Sharp, Sarah; Simmonds, Mark; Stevens, Kim; Unwin, Louise; Whithead, Sally; Dupuy, Bruno; Dougan, Gordon; Barrell, Bart; Parkhill, Julian

Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. (2006) Stabler, RA; Gerding, DN; Songer, JG; Drudy, D; Brazier, JS; Trinh, HT; Witney, AA; Hinds, J; Wren, BW

The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. (2006) Thomson, Nicholas R; Howard, Sarah; Wren, Brendan W; Holden, Matthew TG; Crossman, Lisa; Challis, Gregory L; Churcher, Carol; Mungall, Karen; Brooks, Karen; Chillingworth, Tracey; Feltwell, Theresa; Abdellah, Zahra; Hauser, Heidi; Jagels, Kay; Maddison, Mark; Moule, Sharon; Sanders, Mandy; Whitehead, Sally; Quail, Michael A; Dougan, Gordon; Parkhill, Julian; Prentice, Michael B

The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. (2006) Thomson, Nicholas R; Howard, Sarah; Wren, Brendan W; Holden, Matthew TG; Crossman, Lisa; Challis, Gregory L; Churcher, Carol; Mungall, Karen; Brooks, Karen; Chillingworth, Tracey; Feltwell, Theresa; Abdellah, Zahra; Hauser, Heidi; Jagels, Kay; Maddison, Mark; Moule, Sharon; Sanders, Mandy; Whitehead, Sally; Quail, Michael A; Dougan, Gordon; Parkhill, Julian; Prentice, Michael B

How bacterial pathogens evolve. (2006) Wren, BW

Clostridium difficile comes of age. (2006) Wren, Brendan W

2005

Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. (2005) Champion, Olivia L; Gaunt, Michael W; Gundogdu, Ozan; Elmi, Abdi; Witney, Adam A; Hinds, Jason; Dorrell, Nick; Wren, Brendan W

An investigation into the genetic diversity of the food-borne pathogen campylobacter jejuni using DNA microarrays. (2005) Champion, Olivia Lucy

Advances in Campylobacter jejuni comparative genomics through whole genome DNA microarrays. (2005) Dorrell, N; Champion, OL; Wren, BW

Comparative phylogenomics of pathogenic bacteria by microarray analysis. (2005) Dorrell, Nick; Hinchliffe, Stewart J; Wren, Brendan W

Polysaccharide capsule of Campylobacter jejuni. (2005) Karlyshev, AV; Joshua, GWP; Champion, OL; Wren, BW

Development and application of an insertional system for gene delivery and expression in Campylobacter jejuni. (2005) Karlyshev, AV; Wren, BW

Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses. (2005) Karlyshev, Andrey V; Champion, Olivia L; Churcher, Carol; Brisson, Jean-Robert; Jarrell, Harold C; Gilbert, Michel; Brochu, Denis; St Michael, Frank; Li, Jianjun; Wakarchuk, Warren W; Goodhead, Ian; Sanders, Mandy; Stevens, Kim; White, Brian; Parkhill, Julian; Wren, Brendan W; Szymanski, Christine M

The Campylobacter jejuni glycome. (2005) Karlyshev, Andrey V; Ketley, Julian M; Wren, Brendan W

The complete genome sequence of Francisella tularensis, the causative agent of tularemia. (2005) Larsson, Pär; Oyston, Petra CF; Chain, Patrick; Chu, May C; Duffield, Melanie; Fuxelius, Hans-Henrik; Garcia, Emilio; Hälltorp, Greger; Johansson, Daniel; Isherwood, Karen E; Karp, Peter D; Larsson, Eva; Liu, Ying; Michell, Stephen; Prior, Joann; Prior, Richard; Malfatti, Stephanie; Sjöstedt, Anders; Svensson, Kerstin; Thompson, Nick; Vergez, Lisa; Wagg, Jonathan K; Wren, Brendan W; Lindler, Luther E; Andersson, Siv GE; Forsman, Mats; Titball, Richard W

Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. (2005) Linton, Dennis; Dorrell, Nick; Hitchen, Paul G; Amber, Saba; Karlyshev, Andrey V; Morris, Howard R; Dell, Anne; Valvano, Miguel A; Aebi, Markus; Wren, Brendan W

Explorative multifactor approach for investigating global survival mechanisms of Campylobacter jejuni under environmental conditions. (2005) Moen, Birgitte; Oust, Astrid; Langsrud, Øyvind; Dorrell, Nick; Marsden, Gemma L; Hinds, Jason; Kohler, Achim; Wren, Brendan W; Rudi, Knut

Revised nomenclature of Clostridium difficile toxins and associated genes. (2005) Rupnik, Maja; Dupuy, Bruno; Fairweather, Neil F; Gerding, Dale N; Johnson, Stuart; Just, Ingo; Lyerly, David M; Popoff, Michel R; Rood, Julian I; Sonenshein, Abraham L; Thelestam, Monica; Wren, Brendan W; Wilkins, Tracy D; von Eichel-Streiber, Christoph

Protein glycosylation in bacterial mucosal pathogens. (2005) Szymanski, Christine M; Wren, Brendan W

Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment. (2005) Woodall, CA; Jones, MA; Barrow, PA; Hinds, J; Marsden, GL; Kelly, DJ; Dorrell, N; Wren, BW; Maskell, DJ

Innate immunity: past, present and future. (2005) Wren, BW

Intestinal innate immunity to Campylobacter jejuni results in induction of bactericidal human beta-defensins 2 and 3. (2005) Zilbauer, Matthias; Dorrell, Nick; Boughan, Parjeet K; Harris, Andrew; Wren, Brendan W; Klein, Nigel J; Bajaj-Elliott, Mona

2004

Campylobacter jejuni infection in intestinal lymphoma: A strong association with immunoproliferative small intestinal disease. (2004) Baginsky, LA; Diss, TC; Ye, HT; Wren, B; du, MQ; Isaacson, PG; Dogan, A

Campylobacter jejuni is a strong candidate for involvement in the development of immunoproliferative small intestinal disease. (2004) Diss, TC; Baginsky, L; Ye, H; du, M; Wren, B; Dogan, A; Isaacson, PG

A plasmid immunization construct encoding urease B of Helicobacter pylori induces an antigen-specific antibody response and upregulates the expression of beta-defensins and IL-10 in the stomachs of immunized mice. (2004) Hatzifoti, Caterina; Bajaj-Elliott, Mona; Dorrell, Nick; Anyim, Martin; Prentice, Michael B; Nye, Keith E; Wren, Brendan; Morrow, W John W

Functional analysis of a novel bacterial N-linked protein glycosylation pathway from Campylobacter jejuni. (2004) Hitchen, PG; Linton, D; Dorrel, N; Amber, S; Karlyshev, AV; Morris, HR; Dell, A; Valvano, MA; Aebi, M; Wren, BW

Functional analysis of a novel bacterial N-linked protein glycosylation pathway from Campylobacter jejuni. (2004) Hitchen, PG; Linton, D; Dorrel, N; Amber, S; Karlyshev, AV; Morris, HR; Dell, A; Valvano, MA; Aebi, M; Wren, BW

Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. (2004) Jones, Michael A; Marston, Kerrie L; Woodall, Claire A; Maskell, Duncan J; Linton, Dennis; Karlyshev, Andrey V; Dorrell, Nick; Wren, Brendan W; Barrow, Paul A

The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. (2004) Karlyshev, AV; Everest, P; Linton, D; Cawthraw, S; Newell, DG; Wren, BW

Invertebrates as a source of emerging human pathogens. (2004) Waterfield, Nicholas R; Wren, Brendan W; Ffrench-Constant, Richard H

2003

Genes to genetic immunization: identification of bacterial vaccine candidates. (2003) Allan, Elaine; Wren, Brendan W

Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis. (2003) Hinchliffe, Stewart J; Isherwood, Karen E; Stabler, Richard A; Prentice, Michael B; Rakin, Alexander; Nichols, Richard A; Oyston, Petra CF; Hinds, Jason; Titball, Richard W; Wren, Brendan W

A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface. (2003) Joshua, GWP; Karlyshev, AV; Smith, MP; Isherwood, KE; Titball, RW; Wren, BW

Further strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantitation of DNA-tagged strains. (2003) Karlyshev, AV; Dorrell, N; Winzeler, EA; Wren, BW

Signature-tagged mutagenesis of Yersinia pestis. (2003) Oyston, Petra CF; Karlyshev, Andrey V; Wren, Brendan W; Titball, Richard W

Construction of a Yersinia pestis microarray. (2003) Stabler, Richard A; Hinds, Jason; Witney, Adam A; Isherwood, Karen; Oyston, Petra; Titball, Richard; Wren, Brendan; Hinchliffe, Stewart; Prentice, Michael; Mangan, Joseph A; Butcher, Phillip D

Campylobacter--a tale of two protein glycosylation systems. (2003) Szymanski, Christine M; Logan, Susan M; Linton, Dennis; Wren, Brendan W

The yersiniae--a model genus to study the rapid evolution of bacterial pathogens. (2003) Wren, Brendan W

2002

Application of DNA microarrays for comparative and evolutionary genomics. (2002) Dorrell, N; Champion, OL; Wren, BW

Microarray analysis of campylobacter jejuni: to the guts of the problem! (2002) Dorrell, Nick; Champion, Olivia L; Wren, Brendan W

Immunization with a DNA vaccine expressing a truncated form of varicella zoster virus glycoprotein E. (2002) Hasan, UA; Harper, DR; Wren, BW; Morrow, WJW

Separated at birth? Microarray analysis of two strikingly similar yersinia species. (2002) Hinchliffe, SJ; Isherwood, KE; Stabler, RA; Oyston, PCF; Hinds, J; Titbal, RW; Wren, BW

Structural characterization of lipo-oligosaccharide (LOS) from Yersinia pestis: regulation of LOS structure by the PhoPQ system. (2002) Hitchen, Paul G; Prior, Joann L; Oyston, Petra CF; Panico, Maria; Wren, Brendan W; Titball, Richard W; Morris, Howard R; Dell, Anne

Further strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantification of DNA-tagged strains. (2002) Karlyshev, AV; Dorrell, N; Winzeler, E; Wren, BW

A novel paralogous gene family involved in phase-variable flagella-mediated motility in Campylobacter jejuni. (2002) Karlyshev, Andrey V; Linton, Dennis; Gregson, Norman A; Wren, Brendan W

Exploiting genome sequence: predictions for mechanisms of Campylobacter chemotaxis (vol 10,pg 155, 2002). (2002) Ketley, J; Marchant, J; Wren, B

Identification of N-acetylgalactosamine-containing glycoproteins PEB3 and CgpA in Campylobacter jejuni. (2002) Linton, Dennis; Allan, Elaine; Karlyshev, Andrey V; Cronshaw, Andrew D; Wren, Brendan W

Exploiting genome sequence: predictions for mechanisms of Campylobacter chemotaxis. (2002) Marchant, Joanna; Wren, Brendan; Ketley, Julian

LsaA, an antigen involved in cell attachment and invasion, is expressed by Lawsonia intracellularis during infection in vitro and in vivo. (2002) McCluskey, Jackie; Hannigan, Joanne; Harris, Jennifer D; Wren, Brendan; Smith, David GE

N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. (2002) Wacker, Michael; Linton, Dennis; Hitchen, Paul G; Nita-Lazar, Mihai; Haslam, Stuart M; North, Simon J; Panico, Maria; Morris, Howard R; Dell, Anne; Wren, Brendan W; Aebi, Markus

Methods in microbiology: functional microbial genomics. (2002) Wren, BW; Dorrell, N. (Eds)

Microarrays for bacterial pathogens - hope or hype? (2002) Wren, Brendan W

Deciphering tsetse's secret partner. (2002) Wren, Brendan W

Helicobacter pylori adherence to gastric epithelial cells: a role for non-adhesin virulence genes. (2002) Zhang, Zun-Wu; Dorrell, Nick; Wren, Brendan W; Farthing, Michael JG

2001

Characterization of the low-pH responses of Helicobacter pylori using genomic DNA arrays. (2001) Allan, Elaine; Clayton, Christopher L; McLaren, Alistair; Wallace, Donald M; Wren, Brendan W

Molecular characterization of the surface layer proteins from Clostridium difficile. (2001) Calabi, E; Ward, S; Wren, B; Paxton, T; Panico, M; Morris, H; Dell, A; Dougan, G; Fairweather, N

Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity. (2001) Dorrell, N; Mangan, JA; Laing, KG; Hinds, J; Linton, D; Al-Ghusein, H; Barrell, BG; Parkhill, J; Stoker, NG; Karlyshev, AV; Butcher, PD; Wren, BW

Demonstration of polysaccharide capsule in Campylobacter jejuni using electron microscopy. (2001) Karlyshev, AV; McCrossan, MV; Wren, BW

Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes. (2001) Karlyshev, AV; Oyston, PC; Williams, K; Clark, GC; Titball, RW; Winzeler, EA; Wren, BW

Detection and initial characterization of novel capsular polysaccharide among diverse Campylobacter jejuni strains using alcian blue dye. (2001) Karlyshev, AV; Wren, BW

Deciphering Campylobacter jejuni cell surface interactions from the genome sequence. (2001) Linton, D; Karlyshev, AV; Wren, BW

Helicobacter pylori pore-forming cytolysin orthologue TlyA possesses in vitro hemolytic activity and has a role in colonization of the gastric mucosa. (2001) Martino, MC; Stabler, RA; Zhang, ZW; Farthing, MJ; Wren, BW; Dorrell, N

Genome sequence of Yersinia pestis, the causative agent of plague. (2001) Parkhill, J; Wren, BW; Thomson, NR; Titball, RW; Holden, MT; Prentice, MB; Sebaihia, M; James, KD; Churcher, C; Mungall, KL; Baker, S; Basham, D; Bentley, SD; Brooks, K; Cerdeño-Tárraga, AM; Chillingworth, T; Cronin, A; Davies, RM; Davis, P; Dougan, G; Feltwell, T; Hamlin, N; Holroyd, S; Jagels, K; Karlyshev, AV; Leather, S; Moule, S; Oyston, PC; Quail, M; Rutherford, K; Simmonds, M; Skelton, J; Stevens, K; Whitehead, S; Barrell, BG

Yersinia pestis pFra shows biovar-specific differences and recent common ancestry with a Salmonella enterica serovar Typhi plasmid. (2001) Prentice, MB; James, KD; Parkhill, J; Baker, SG; Stevens, K; Simmonds, MN; Mungall, KL; Churcher, C; Oyston, PC; Titball, RW; Wren, BW; Wain, J; Pickard, D; Hien, TT; Farrar, JJ; Dougan, G

Characterization of the lipopolysaccharide of Yersinia pestis. (2001) Prior, JL; Hitchen, PG; Williamson, DE; Reason, AJ; Morris, HR; Dell, A; Wren, BW; Titball, RW

The failure of different strains of Yersinia pestis to produce lipopolysaccharide O-antigen under different growth conditions is due to mutations in the O-antigen gene cluster. (2001) Prior, JL; Parkhill, J; Hitchen, PG; Mungall, KL; Stevens, K; Morris, HR; Reason, AJ; Oyston, PC; Dell, A; Wren, BW; Titball, RW

Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4. (2001) Prior, RG; Klasson, L; Larsson, P; Williams, K; Lindler, L; Sjöstedt, A; Svensson, T; Tamas, I; Wren, BW; Oyston, PC; Andersson, SG; Titball, RW

Clostridium difficile. (2001) Wren, B

Chameleonbacter jejuni - the changing sugar coat of a foodborne pathogen. (2001) Wren, BW

Post genome analysis of Campylobacter jejuni. (2001) Wren, BW; Linton, D; Dorrell, N; Karlyshev, AV