Items where Author is "Wren, Brendan W"
Number of items: 355.
Bibliographic data only
All Yersinia enterocolitica are pathogenic: virulence of phylogroup 1 Y. enterocolitica in a Galleria mellonella infection model. (2016)
Alenizi, Dhahi; Ringwood, Tamara; Redhwan, Alya; Bouraha, Bouchra; Wren, Brendan W; Prentice, Michael; McNally, Alan
THE ROLE OF MLTD AND RPON IN H. PYLORI BIOFILM FORMATION IN VITRO. (2013)
Alhaj-Hussein, BT; Kazakos, EI; Wren, BW; Dorrell, N
Characterization of the low-pH responses of Helicobacter pylori using genomic DNA arrays. (2001)
Allan, Elaine; Clayton, Christopher L; McLaren, Alistair; Wallace, Donald M; Wren, Brendan W
Genes to genetic immunization: identification of bacterial vaccine candidates. (2003)
Allan, Elaine; Wren, Brendan W
YtxR acts as an overriding transcriptional off switch for the Yersinia enterocolitica Ysc-Yop type 3 secretion system. (2008)
Axler-DiPerte, Grace L; Hinchliffe, Stewart J; Wren, Brendan W; Darwin, Andrew J
Campylobacter jejuni infection in intestinal lymphoma: A strong association with immunoproliferative small intestinal disease. (2004)
Baginsky, LA; Diss, TC; Ye, HT; Wren, B; du, MQ; Isaacson, PG; Dogan, A
Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli. (2013)
Birchenough, George MH; Johansson, Malin EV; Stabler, Richard A; Dalgakiran, Fatma; Hansson, Gunnar C; Wren, Brendan W; Luzio, J Paul; Taylor, Peter W
Corrigendum to ‘Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae’ [Veterinary Microbiology 178 (2015) 279–282]. (2015)
Bossé, Janine T; Li, Yanwen; Atherton, Tom G; Walker, Stephanie; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R
Correction for Cairns et al., "Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages". (2017)
Cairns, MD; Preston, MD; Hall, CL; Gerding, DN; Hawkey, PM; Kato, H; Kim, H; Kuijper, EJ; Lawley, TD; Pituch, H; Reid, S; Kullin, B; Riley, TV; Solomon, K; Tsai, PJ; Weese, JS; Stabler, RA; Wren, BW
The continually evolving Clostridium difficile species. (2012)
Cairns, Michelle D; Stabler, Richard A; Shetty, Nandini; Wren, Brendan W
Molecular characterization of the surface layer proteins from Clostridium difficile. (2001)
Calabi, E; Ward, S; Wren, B; Paxton, T; Panico, M; Morris, H; Dell, A; Dougan, G; Fairweather, N
The RovA regulons of Yersinia enterocolitica and Yersinia pestis are distinct: evidence that many RovA-regulated genes were acquired more recently than the core genome. (2007)
Cathelyn, Jason S; Ellison, Damon W; Hinchliffe, Stewart J; Wren, Brendan W; Miller, Virginia L
Comparative genomics of Campylobacter jejuni. (2008)
Champion, O; Al-Jaberi, S; Stabler, R; Wren, B
Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis. (2009)
Champion, Olivia L; Cooper, Ian AM; James, Sarah L; Ford, Donna; Karlyshev, Andrey; Wren, Brendan W; Duffield, Melanie; Oyston, Petra CF; Titball, Richard W
Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. (2005)
Champion, Olivia L; Gaunt, Michael W; Gundogdu, Ozan; Elmi, Abdi; Witney, Adam A; Hinds, Jason; Dorrell, Nick; Wren, Brendan W
Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity. (2010)
Champion, Olivia L; Karlyshev, Andrey V; Senior, Nicola J; Woodward, Martin; La Ragione, Roberto; Howard, Sarah L; Wren, Brendan W; Titball, Richard W
Yersinia pseudotuberculosis mntH functions in intracellular manganese accumulation, which is essential for virulence and survival in cells expressing functional Nramp1. (2010)
Champion, Olivia L; Karlyshev, Andrey; Cooper, Ian AM; Ford, Donna C; Wren, Brendan W; Duffield, Melanie; Oyston, Petra CF; Titball, Richard W
The identification of two protective DNA vaccines from a panel of five plasmid constructs encoding Brucella melitensis 16M genes. (2007)
Commander, Nicola J; Spencer, Stephen A; Wren, Brendan W; MacMillan, Alastair P
Campylobacter jejuni cocultured with epithelial cells reduces surface capsular polysaccharide expression. (2009)
Corcionivoschi, N; Clyne, M; Lyons, A; Elmi, A; Gundogdu, O; Wren, BW; Dorrell, N; Karlyshev, AV; Bourke, B
Alteration in bacterial capsular polysaccharides following co-culture with human epithelial cells. (2007)
Corcionivoschi, N; Clyne, M; Lyons, A; Lamoureux, M; Wren, B; Dorell, N; Karlyshev, A; Szymanski, C; Bourke, B
Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. (2006)
Cuccui, J; Easton, A; Chu, KK; Bancroft, GJ; Oyston, PCF; Titball, RW; Wren, BW
Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region. (2012)
Cuccui, Jon; Milne, Timothy S; Harmer, Nicholas; George, Alison J; Harding, Sarah V; Dean, Rachel E; Scott, Andrew E; Sarkar-Tyson, Mitali; Wren, Brendan W; Titball, Richard W; Prior, Joann L
Bacteria like sharing their sweets. (2013)
Cuccui, Jon; Wren, Brendan W
Comparative genomics of Clostridium difficile. (2009)
Dawson, LF; Stabler, RA; Wren, BW
Assessing the role of p-cresol tolerance in Clostridium difficile. (2008)
Dawson, Lisa F; Stabler, Richard A; Wren, Brendan W
Clostridium difficile--a continually evolving and problematic pathogen. (2009)
Dawson, Lisa F; Valiente, Esmeralda; Wren, Brendan W
The Clostridium difficile spo0A gene is a persistence and transmission factor. (2012)
Deakin, Laura J; Clare, Simon; Fagan, Robert P; Dawson, Lisa F; Pickard, Derek J; West, Michael R; Wren, Brendan W; Fairweather, Neil F; Dougan, Gordon; Lawley, Trevor D
Campylobacter jejuni is a strong candidate for involvement in the development of immunoproliferative small intestinal disease. (2004)
Diss, TC; Baginsky, L; Ye, H; du, M; Wren, B; Dogan, A; Isaacson, PG
Advances in Campylobacter jejuni comparative genomics through whole genome DNA microarrays. (2005)
Dorrell, N; Champion, OL; Wren, BW
Application of DNA microarrays for comparative and evolutionary genomics. (2002)
Dorrell, N; Champion, OL; Wren, BW
Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity. (2001)
Dorrell, N; Mangan, JA; Laing, KG; Hinds, J; Linton, D; Al-Ghusein, H; Barrell, BG; Parkhill, J; Stoker, NG; Karlyshev, AV; Butcher, PD; Wren, BW
Comparative phylogenomics of pathogenic bacteria by microarray analysis. (2005)
Dorrell, Nick; Hinchliffe, Stewart J; Wren, Brendan W
The second century of Campylobacter research: recent advances, new opportunities and old problems. (2007)
Dorrell, Nick; Wren, Brendan W
Campylobacter jejuni outer membrane vesicles possess proteolytic activity and enhance bacterial adhesion to and invasion of intestinal epithelial cells. (2013)
Elmi, A; Naz, N; Gundogdu, O; Wren, BW; Dorrell, N
Investigation of the role of two Campylobacter jejuni glycoproteins during bacterial interactions with human intestinal epithelial cells. (2007)
Elmi, AD; Zilbauer, M; Bajaj-Elliott, M; Wren, B; Dorrell, N
Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress. (2008)
Emerson, Jenny E; Stabler, Richard A; Wren, Brendan W; Fairweather, Neil F
Serotype differences and lack of biofilm formation characterize Yersinia pseudotuberculosis infection of the Xenopsylla cheopis flea vector of Yersinia pestis. (2006)
Erickson, David L; Jarrett, Clayton O; Wren, Brendan W; Hinnebusch, B Joseph
The importance of the magnesium transporter MgtB for virulence of Yersinia pseudotuberculosis and Yersinia pestis. (2014)
Ford, Donna C; Joshua, George WP; Wren, Brendan W; Oyston, Petra CF
Role of the Cj1371 periplasmic protein and the Cj0355c two-component regulator in the Campylobacter jejuni NCTC 11168 response to oxidative stress caused by paraquat. (2008)
Garénaux, Amélie; Guillou, Sandrine; Ermel, Gwennola; Wren, Brendan; Federighi, Michel; Ritz, Magali
Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome and functional characterisation of selected genes involved in strain pathogenesis. (2007)
Gundogdu, O; Martin, MJ; Bentley, SD; Holden, MT; Parkhill, J; Wren, BW; Dorrell, N
Variation in the distribution of the MarR-type transcriptional regulators Cj1546 and Cj1556 amongst Campylobacter jejuni strains correlates with differences in resistance to oxidative and aerobic stress. (2013)
Gundogdu, O; Mohammed, B; Teixeira, DDS; Elmi, A; Wren, BW; Dorrell, N
Genetic Mechanisms Involved in Campylobacter jejuni Survival Under Oxidative Stress Conditions. (2014)
Gundogdu, O; Wren, BW; Dorrell, N
Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease. (2013)
Hargreaves, Chantal E; Grasso, Marco; Hampe, Christiane S; Stenkova, Anna; Atkinson, Steve; Joshua, George WP; Wren, Brendan W; Buckle, Ashley M; Dunn-Walters, Deborah; Banga, J Paul
Immunization with a DNA vaccine expressing a truncated form of varicella zoster virus glycoprotein E. (2002)
Hasan, UA; Harper, DR; Wren, BW; Morrow, WJW
A plasmid immunization construct encoding urease B of Helicobacter pylori induces an antigen-specific antibody response and upregulates the expression of beta-defensins and IL-10 in the stomachs of immunized mice. (2004)
Hatzifoti, Caterina; Bajaj-Elliott, Mona; Dorrell, Nick; Anyim, Martin; Prentice, Michael B; Nye, Keith E; Wren, Brendan; Morrow, W John W
Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori. (2006)
Hatzifoti, Caterina; Roussel, Yvonne; Harris, Andrew G; Wren, Brendan W; Morrow, John W; Bajaj-Elliott, Mona
Evolutionary dynamics of Clostridium difficile over short and long time scales. (2010)
He, Miao; Sebaihia, Mohammed; Lawley, Trevor D; Stabler, Richard A; Dawson, Lisa F; Martin, Melissa J; Holt, Kathryn E; Seth-Smith, Helena MB; Quail, Michael A; Rance, Richard; Brooks, Karen; Churcher, Carol; Harris, David; Bentley, Stephen D; Burrows, Christine; Clark, Louise; Corton, Craig; Murray, Vicky; Rose, Graham; Thurston, Scott; van Tonder, Andries; Walker, Danielle; Wren, Brendan W; Dougan, Gordon; Parkhill, Julian
Evolution of Pathogenic Yersinia. (2007)
Hinchliffe, S; Strong, P; Howard, S; Wren, B
Evolution of Pathogen Yersinia. (2008)
Hinchliffe, SJ; Strong, PCR; Howard, SL; Wren, BW
The importance of the Rcs phosphorelay in the survival and pathogenesis of the enteropathogenic yersiniae. (2008)
Hinchliffe, Stewart J; Howard, Sarah L; Huang, Yahui H; Clarke, David J; Wren, Brendan W
Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis. (2003)
Hinchliffe, Stewart J; Isherwood, Karen E; Stabler, Richard A; Prentice, Michael B; Rakin, Alexander; Nichols, Richard A; Oyston, Petra CF; Hinds, Jason; Titball, Richard W; Wren, Brendan W
Functional analysis of a novel bacterial N-linked protein glycosylation pathway from Campylobacter jejuni. (2004)
Hitchen, PG; Linton, D; Dorrel, N; Amber, S; Karlyshev, AV; Morris, HR; Dell, A; Valvano, MA; Aebi, M; Wren, BW
Functional analysis of a novel bacterial N-linked protein glycosylation pathway from Campylobacter jejuni. (2004)
Hitchen, PG; Linton, D; Dorrel, N; Amber, S; Karlyshev, AV; Morris, HR; Dell, A; Valvano, MA; Aebi, M; Wren, BW
Structural characterization of lipo-oligosaccharide (LOS) from Yersinia pestis: regulation of LOS structure by the PhoPQ system. (2002)
Hitchen, Paul G; Prior, Joann L; Oyston, Petra CF; Panico, Maria; Wren, Brendan W; Titball, Richard W; Morris, Howard R; Dell, Anne
Glycoproteomics: a powerful tool for characterizing the diverse glycoforms of bacterial pilins and flagellins. (2010)
Hitchen, Paul G; Twigger, Katie; Valiente, Esmeralda; Langdon, Rebecca H; Wren, Brendan W; Dell, Anne
The Three Bears and Virulence-Associated Plasmids in the Genus Yersinia. (2009)
Howard, SL; Strong, PC; Wren, BW
Application of comparative phylogenomics to study the evolution of Yersinia enterocolitica and to identify genetic differences relating to pathogenicity. (2006)
Howard, Sarah L; Gaunt, Michael W; Hinds, Jason; Witney, Adam A; Stabler, Richard; Wren, Brendan W
Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. (2009)
Howard, Sarah L; Jagannathan, Aparna; Soo, Evelyn C; Hui, Joseph PM; Aubry, Annie J; Ahmed, Imran; Karlyshev, Andrey; Kelly, John F; Jones, Michael A; Stevens, Mark P; Logan, Susan M; Wren, Brendan W
Development of a Multiplex PCR Assay for Rapid Molecular Serotyping of Haemophilus parasuis. (2015)
Howell, Kate J; Peters, Sarah E; Wang, Jinhong; Hernandez-Garcia, Juan; Weinert, Lucy A; Luan, Shi-Lu; Chaudhuri, Roy R; Angen, Øystein; Aragon, Virginia; Williamson, Susanna M; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W; BRaDP1T Consortium
Gene content and diversity of the loci encoding biosynthesis of capsular polysaccharides of the 15 serovar reference strains of Haemophilus parasuis. (2013)
Howell, Kate J; Weinert, Lucy A; Luan, Shi-Lu; Peters, Sarah E; Chaudhuri, Roy R; Harris, David; Angen, Oystein; Aragon, Virginia; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium
Host immunity to Clostridium difficile PCR ribotype 017 strains. (2014)
Jafari, Nazila V; Songane, Mario; Stabler, Richard A; Elawad, Mamoun; Wren, Brendan W; Allan, Elaine; Bajaj-Elliott, Mona
Functional characterisation of the Campylobacter jejuni NCTC11168H flagellin glycosylation island in the avian host. (2007)
Jagannathan, A; Howard, S; Stevens, MP; Jones, MA; Wren, BW
Characterization of the structurally diverse N-linked glycans of Campylobacter species. (2012)
Jervis, Adrian J; Butler, Jonathan A; Lawson, Andrew J; Langdon, Rebecca; Wren, Brendan W; Linton, Dennis
Characterization of N-linked protein glycosylation in Helicobacter pullorum. (2010)
Jervis, Adrian J; Langdon, Rebecca; Hitchen, Paul; Lawson, Andrew J; Wood, Alison; Fothergill, Joanne L; Morris, Howard R; Dell, Anne; Wren, Brendan; Linton, Dennis
Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. (2004)
Jones, Michael A; Marston, Kerrie L; Woodall, Claire A; Maskell, Duncan J; Linton, Dennis; Karlyshev, Andrey V; Dorrell, Nick; Wren, Brendan W; Barrow, Paul A
Biofilm formation in Campylobacter jejuni. (2006)
Joshua, GWP; Guthrie-Irons, C; Karlyshev, AV; Wren, BW
A Caenorhabditis elegans model of Yersinia infection: biofilm formation on a biotic surface. (2003)
Joshua, GWP; Karlyshev, AV; Smith, MP; Isherwood, KE; Titball, RW; Wren, BW
Genome-wide evaluation of the interplay between Caenorhabditis elegans and Yersinia pseudotuberculosis during in vivo biofilm formation. (2014)
Joshua, George WP; Atkinson, Steve; Goldstone, Robert J; Patrick, Hannah L; Stabler, Richard A; Purves, Joanne; Cámara, Miguel; Williams, Paul; Wren, Brendan W
Deletion of a previously uncharacterized flagellar-hook-length control gene fliK modulates the sigma54-dependent regulon in Campylobacter jejuni. (2007)
Kamal, Nahid; Dorrell, Nick; Jagannathan, Aparna; Turner, Susan M; Constantinidou, Chrystala; Studholme, David J; Marsden, Gemma; Hinds, Jason; Laing, Ken G; Wren, Brendan W; Penn, Charles W
Genetics and properties of a novel capsule produced by untypable strain X of C-jejuni. (2007)
Karlyshev, A; Quail, MA; Stevens, K; Elmi, A; Parkhill, J; Wren, BW
Campylobacter proteases and their role in colonisation and stress responses. (2007)
Karlyshev, A; Thacker, G; Jones, MA; Clements, MO; Wren, BW
Campylobacter jejuni capsule polysaccharide. (2008)
Karlyshev, A; Wren, B; Moran, A
Further strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantification of DNA-tagged strains. (2002)
Karlyshev, AV; Dorrell, N; Winzeler, E; Wren, BW
Further strategies for signature-tagged mutagenesis and the application of oligonucleotide microarrays for the quantitation of DNA-tagged strains. (2003)
Karlyshev, AV; Dorrell, N; Winzeler, EA; Wren, BW
The Campylobacter jejuni general glycosylation system is important for attachment to human epithelial cells and in the colonization of chicks. (2004)
Karlyshev, AV; Everest, P; Linton, D; Cawthraw, S; Newell, DG; Wren, BW
Polysaccharide capsule of Campylobacter jejuni. (2005)
Karlyshev, AV; Joshua, GWP; Champion, OL; Wren, BW
Demonstration of polysaccharide capsule in Campylobacter jejuni using electron microscopy. (2001)
Karlyshev, AV; McCrossan, MV; Wren, BW
Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes. (2001)
Karlyshev, AV; Oyston, PC; Williams, K; Clark, GC; Titball, RW; Winzeler, EA; Wren, BW
Unusual features in organisation of capsular polysaccharide-related genes of C. jejuni strain X. (2013)
Karlyshev, AV; Quail, MA; Parkhill, J; Wren, BW
Development and application of an insertional system for gene delivery and expression in Campylobacter jejuni. (2005)
Karlyshev, AV; Wren, BW
Detection and initial characterization of novel capsular polysaccharide among diverse Campylobacter jejuni strains using alcian blue dye. (2001)
Karlyshev, AV; Wren, BW
Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses. (2005)
Karlyshev, Andrey V; Champion, Olivia L; Churcher, Carol; Brisson, Jean-Robert; Jarrell, Harold C; Gilbert, Michel; Brochu, Denis; St Michael, Frank; Li, Jianjun; Wakarchuk, Warren W; Goodhead, Ian; Sanders, Mandy; Stevens, Kim; White, Brian; Parkhill, Julian; Wren, Brendan W; Szymanski, Christine M
The Campylobacter jejuni glycome. (2005)
Karlyshev, Andrey V; Ketley, Julian M; Wren, Brendan W
A novel paralogous gene family involved in phase-variable flagella-mediated motility in Campylobacter jejuni. (2002)
Karlyshev, Andrey V; Linton, Dennis; Gregson, Norman A; Wren, Brendan W
Post-genome Analysis of the Foodborne Pathogen Campylobacter jejuni. (2011)
Kay, E; Gundogdu, O; Wren, B
Systems analysis of bacterial glycomes. (2010)
Kay, Emily; Lesk, Victor I; Tamaddoni-Nezhad, Alireza; Hitchen, Paul G; Dell, Anne; Sternberg, Michael J; Muggleton, Stephen; Wren, Brendan W
Recent advances in systems microbiology. (2009)
Kay, Emily; Wren, Brendan W
Exploiting genome sequence: predictions for mechanisms of Campylobacter chemotaxis (vol 10,pg 155, 2002). (2002)
Ketley, J; Marchant, J; Wren, B
Phenotypic and genotypic characterization of enteroaggregative Escherichia coli isolates from pediatric population in Pakistan. (2016)
Khalil, Uzma; Younus, Mahwish; Asghar, Naeem; Siddiqui, Fariha; Gómez-Duarte, Oscar G; Wren, Brendan W; Bokhari, Habib
Growth inhibition of pathogenic bacteria by sulfonylurea herbicides. (2013)
Kreisberg, Jason F; Ong, Nicholas T; Krishna, Aishwarya; Joseph, Thomas L; Wang, Jing; Ong, Catherine; Ooi, Hui Ann; Sung, Julie C; Siew, Chern Chiang; Chang, Grace C; Biot, Fabrice; Cuccui, Jon; Wren, Brendan W; Chan, Joey; Sivalingam, Suppiah P; Zhang, Lian-Hui; Verma, Chandra; Tan, Patrick
Phenotypic and genotypic characterizations of Campylobacter jejuni isolated from the broiler meat production process. (2012)
Kudirkienė, Eglė; Cohn, Marianne Thorup; Stabler, Richard A; Strong, Philippa CR; Sernienė, Loreta; Wren, Brendan W; Nielsen, Eva Møller; Malakauskas, Mindaugas; Brøndsted, Lone
Characterisation of the Campylobacter jejuni major antigenic protein PEB3. (2007)
Langdon, RH; Linton, D; Hinchliffe, S; Cawthraw, S; Newell, D; Wren, B
N-linked glycosylation in bacteria: an unexpected application. (2009)
Langdon, Rebecca H; Cuccui, Jon; Wren, Brendan W
The complete genome sequence of Francisella tularensis, the causative agent of tularemia. (2005)
Larsson, Pär; Oyston, Petra CF; Chain, Patrick; Chu, May C; Duffield, Melanie; Fuxelius, Hans-Henrik; Garcia, Emilio; Hälltorp, Greger; Johansson, Daniel; Isherwood, Karen E; Karp, Peter D; Larsson, Eva; Liu, Ying; Michell, Stephen; Prior, Joann; Prior, Richard; Malfatti, Stephanie; Sjöstedt, Anders; Svensson, Kerstin; Thompson, Nick; Vergez, Lisa; Wagg, Jonathan K; Wren, Brendan W; Lindler, Luther E; Andersson, Siv GE; Forsman, Mats; Titball, Richard W
Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. (2009)
Lawley, Trevor D; Clare, Simon; Walker, Alan W; Goulding, David; Stabler, Richard A; Croucher, Nicholas; Mastroeni, Piero; Scott, Paul; Raisen, Claire; Mottram, Lynda; Fairweather, Neil F; Wren, Brendan W; Parkhill, Julian; Dougan, Gordon
Effect of chicken meat environment on gene expression of Campylobacter jejuni and its relevance to survival in food. (2011)
Ligowska, Małgorzata; Cohn, Marianne Thorup; Stabler, Richard A; Wren, Brendan W; Brøndsted, Lone
Deciphering Campylobacter jejuni cell surface interactions from the genome sequence. (2001)
Linton, D; Karlyshev, AV; Wren, BW
Identification of N-acetylgalactosamine-containing glycoproteins PEB3 and CgpA in Campylobacter jejuni. (2002)
Linton, Dennis; Allan, Elaine; Karlyshev, Andrey V; Cronshaw, Andrew D; Wren, Brendan W
Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. (2005)
Linton, Dennis; Dorrell, Nick; Hitchen, Paul G; Amber, Saba; Karlyshev, Andrey V; Morris, Howard R; Dell, Anne; Valvano, Miguel A; Aebi, Markus; Wren, Brendan W
Genome sequence of the emerging pathogen Helicobacter canadensis. (2009)
Loman, NJ; Snyder, LAS; Linton, JD; Langdon, R; Lawson, AJ; Weinstock, GM; Wren, BW; Pallen, MJ
Generation of a Tn5 transposon library in Haemophilus parasuis and analysis by transposon-directed insertion-site sequencing (TraDIS). (2013)
Luan, Shi-Lu; Chaudhuri, Roy R; Peters, Sarah E; Mayho, Matthew; Weinert, Lucy A; Crowther, Sarah A; Wang, Jinhong; Langford, Paul R; Rycroft, Andrew; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium
Exploiting genome sequence: predictions for mechanisms of Campylobacter chemotaxis. (2002)
Marchant, Joanna; Wren, Brendan; Ketley, Julian
Helicobacter pylori pore-forming cytolysin orthologue TlyA possesses in vitro hemolytic activity and has a role in colonization of the gastric mucosa. (2001)
Martino, MC; Stabler, RA; Zhang, ZW; Farthing, MJ; Wren, BW; Dorrell, N
LsaA, an antigen involved in cell attachment and invasion, is expressed by Lawsonia intracellularis during infection in vitro and in vivo. (2002)
McCluskey, Jackie; Hannigan, Joanne; Harris, Jennifer D; Wren, Brendan; Smith, David GE
'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution. (2016)
McNally, Alan; Thomson, Nicholas R; Reuter, Sandra; Wren, Brendan W
Where molecular pathogenesis and NMR spectroscopy collide: An integrated approach towards the development of it CPS-based therapy for Campylobacter jejuni. (2006)
McNally, DJ; Jarrell, HC; Lamoureux, M; Coleman, RA; Karlyshev, AV; Wren, BW; Brisson, JR; Szymanski, CM
Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. (2007)
McNally, David J; Lamoureux, Marc P; Karlyshev, Andrey V; Fiori, Laura M; Li, Jianjun; Thacker, Gillian; Coleman, Russell A; Khieu, Nam H; Wren, Brendan W; Brisson, Jean-Robert; Jarrell, Harold C; Szymanski, Christine M
Explorative multifactor approach for investigating global survival mechanisms of Campylobacter jejuni under environmental conditions. (2005)
Moen, Birgitte; Oust, Astrid; Langsrud, Øyvind; Dorrell, Nick; Marsden, Gemma L; Hinds, Jason; Kohler, Achim; Wren, Brendan W; Rudi, Knut
Reinvestigation into the mechanisms of Campylobacter jejuni invasion of intestinal epithelial cells. (2013)
Naz, N; Taylor, E; Gundogdu, O; Elmi, A; Wren, BW; Dorrell, N
Enteric bacterial invasion of intestinal epithelial cells in vitro is dramatically enhanced using a vertical diffusion chamber model. (2013)
Naz, Neveda; Mills, Dominic C; Wren, Brendan W; Dorrell, Nick
Identification of immunogenic and virulence-associated Campylobacter jejuni proteins. (2012)
Nielsen, Lene N; Luijkx, Thomas A; Vegge, Christina S; Johnsen, Christina Kofoed; Nuijten, Piet; Wren, Brendan W; Ingmer, Hanne; Krogfelt, Karen A
Numerical analysis of DNA microarray data of Campylobacter jejuni strains correlated with survival, cytolethal distending toxin and haemolysin analyses. (2006)
On, Stephen LW; Dorrell, Nick; Petersen, Lise; Bang, Dang D; Morris, Samantha; Forsythe, Stephen J; Wren, Brendan W
Signature-tagged mutagenesis of Yersinia pestis. (2003)
Oyston, Petra CF; Karlyshev, Andrey V; Wren, Brendan W; Titball, Richard W
Bacterial pathogenomics. (2007)
Pallen, Mark J; Wren, Brendan W
Galleria mellonella is an effective model to study Actinobacillus pleuropneumoniae infection. (2014)
Pereira, Monalessa Fábia; Rossi, Ciro César; Vieira de Queiroz, Marisa; Martins, Gustavo Ferreira; Isaac, Clement; Bossé, Janine T; Li, Yanwen; Wren, Brendan W; Terra, Vanessa Sofia; Cuccui, Jon; Langford, Paul R; Bazzolli, Denise Mara Soares
Yersinia pestis pFra shows biovar-specific differences and recent common ancestry with a Salmonella enterica serovar Typhi plasmid. (2001)
Prentice, MB; James, KD; Parkhill, J; Baker, SG; Stevens, K; Simmonds, MN; Mungall, KL; Churcher, C; Oyston, PC; Titball, RW; Wren, BW; Wain, J; Pickard, D; Hien, TT; Farrar, JJ; Dougan, G
Characterization of the lipopolysaccharide of Yersinia pestis. (2001)
Prior, JL; Hitchen, PG; Williamson, DE; Reason, AJ; Morris, HR; Dell, A; Wren, BW; Titball, RW
The failure of different strains of Yersinia pestis to produce lipopolysaccharide O-antigen under different growth conditions is due to mutations in the O-antigen gene cluster. (2001)
Prior, JL; Parkhill, J; Hitchen, PG; Mungall, KL; Stevens, K; Morris, HR; Reason, AJ; Oyston, PC; Dell, A; Wren, BW; Titball, RW
Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4. (2001)
Prior, RG; Klasson, L; Larsson, P; Williams, K; Lindler, L; Sjöstedt, A; Svensson, T; Tamas, I; Wren, BW; Oyston, PC; Andersson, SG; Titball, RW
Parallel independent evolution of pathogenicity within the genus Yersinia. (2014)
Reuter, Sandra; Connor, Thomas R; Barquist, Lars; Walker, Danielle; Feltwell, Theresa; Harris, Simon R; Fookes, Maria; Hall, Miquette E; Petty, Nicola K; Fuchs, Thilo M; Corander, Jukka; Dufour, Muriel; Ringwood, Tamara; Savin, Cyril; Bouchier, Christiane; Martin, Liliane; Miettinen, Minna; Shubin, Mikhail; Riehm, Julia M; Laukkanen-Ninios, Riikka; Sihvonen, Leila M; Siitonen, Anja; Skurnik, Mikael; Falcão, Juliana Pfrimer; Fukushima, Hiroshi; Scholz, Holger C; Prentice, Michael B; Wren, Brendan W; Parkhill, Julian; Carniel, Elisabeth; Achtman, Mark; McNally, Alan; Thomson, Nicholas R
Cellular response of Campylobacter jejuni to trisodium phosphate. (2012)
Riedel, Charlotte Tandrup; Cohn, Marianne Thorup; Stabler, Richard A; Wren, Brendan; Brøndsted, Lone
Neutrophil extracellular traps exhibit antibacterial activity against burkholderia pseudomallei and are influenced by bacterial and host factors. (2012)
Riyapa, Donporn; Buddhisa, Surachat; Korbsrisate, Sunee; Cuccui, Jon; Wren, Brendan W; Stevens, Mark P; Ato, Manabu; Lertmemongkolchai, Ganjana
The Campylobacter jejuni NCTC11168 capsule prevents excessive cytokine production by dendritic cells. (2011)
Rose, Anna; Kay, Emily; Wren, Brendan W; Dallman, Margaret J
Revised nomenclature of Clostridium difficile toxins and associated genes. (2005)
Rupnik, Maja; Dupuy, Bruno; Fairweather, Neil F; Gerding, Dale N; Johnson, Stuart; Just, Ingo; Lyerly, David M; Popoff, Michel R; Rood, Julian I; Sonenshein, Abraham L; Thelestam, Monica; Wren, Brendan W; Wilkins, Tracy D; von Eichel-Streiber, Christoph
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. (2006)
Sebaihia, Mohammed; Wren, Brendan W; Mullany, Peter; Fairweather, Neil F; Minton, Nigel; Stabler, Richard; Thomson, Nicholas R; Roberts, Adam P; Cerdeño-Tárraga, Ana M; Wang, Hongmei; Holden, Matthew TG; Wright, Anne; Churcher, Carol; Quail, Michael A; Baker, Stephen; Bason, Nathalie; Brooks, Karen; Chillingworth, Tracey; Cronin, Ann; Davis, Paul; Dowd, Linda; Fraser, Audrey; Feltwell, Theresa; Hance, Zahra; Holroyd, Simon; Jagels, Kay; Moule, Sharon; Mungall, Karen; Price, Claire; Rabbinowitsch, Ester; Sharp, Sarah; Simmonds, Mark; Stevens, Kim; Unwin, Louise; Whithead, Sally; Dupuy, Bruno; Dougan, Gordon; Barrell, Bart; Parkhill, Julian
Molecular detection identified a type six secretion system in Campylobacter jejuni from various sources but not from human cases. (2015)
Siddiqui, F; Champion, O; Akram, M; Studholme, D; Eqani, SAMAS; Wren, BW; Titball, R; Bokhari, H
Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. (2006)
Stabler, RA; Gerding, DN; Songer, JG; Drudy, D; Brazier, JS; Trinh, HT; Witney, AA; Hinds, J; Wren, BW
Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences. (2008)
Stabler, Richard A; Dawson, Lisa F; Phua, Leslie TH; Wren, Brendan W
Construction of a Yersinia pestis microarray. (2003)
Stabler, Richard A; Hinds, Jason; Witney, Adam A; Isherwood, Karen; Oyston, Petra; Titball, Richard; Wren, Brendan; Hinchliffe, Stewart; Prentice, Michael; Mangan, Joseph A; Butcher, Phillip D
Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays. (2013)
Stabler, Richard A; Larsson, Jonas T; Al-Jaberi, Suaad; Nielsen, Eva M; Kay, Emily; Tam, Clarence C; Higgins, Craig D; Rodrigues, Laura C; Richardson, Judith F; O'Brien, Sarah J; Wren, Brendan W
In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions. (2010)
Stabler, Richard A; Valiente, Esmeralda; Dawson, Lisa F; He, Miao; Parkhill, Julian; Wren, Brendan W
Clostridium difficile using DNA microarrays. (2010)
Stabler, Richard; Dawson, Lisa; Wren, Brendan
Campylobacter jejuni lipooligosaccharide sialylation, phosphorylation, and amide/ester linkage modifications fine-tune human Toll-like receptor 4 activation. (2013)
Stephenson, Holly N; John, Constance M; Naz, Neveda; Gundogdu, Ozan; Dorrell, Nick; Wren, Brendan W; Jarvis, Gary A; Bajaj-Elliott, Mona
Campylobacter--a tale of two protein glycosylation systems. (2003)
Szymanski, Christine M; Logan, Susan M; Linton, Dennis; Wren, Brendan W
Protein glycosylation in bacterial mucosal pathogens. (2005)
Szymanski, Christine M; Wren, Brendan W
Recent developments in bacterial protein glycan coupling technology and glycoconjugate vaccine design. (2012)
Terra, Vanessa S; Mills, Dominic C; Yates, Laura E; Abouelhadid, Sherif; Cuccui, Jon; Wren, Brendan W
Comparative genome analyses of the pathogenic Yersiniae based on the genome sequence of Yersinia enterocolitica strain 8081. (2007)
Thomson, Nicholas R; Howard, Sarah; Wren, Brendan W; Prentice, Michael B
Burkholderia pseudomallei: animal models of infection. (2008)
Titball, Richard W; Russell, Paul; Cuccui, Jon; Easton, Anna; Haque, Ashraful; Atkins, Tim; Sarkar-Tyson, Mitali; Harley, Vicki; Wren, Brendan; Bancroft, Gregory J
Identification of Type VI secretion system (T6SS) in Spanish Campylobacter jejuni. (2013)
Ugarte-Ruiz, M; Gundogdu, O; Wassenaar, T; Ancochea, C; Porrero, MC; Wren, BW; Dorrell, N; Dominguez, L
The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move. (2014)
Valiente, E; Cairns, MD; Wren, BW
N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. (2002)
Wacker, Michael; Linton, Dennis; Hitchen, Paul G; Nita-Lazar, Mihai; Haslam, Stuart M; North, Simon J; Panico, Maria; Morris, Howard R; Dell, Anne; Wren, Brendan W; Aebi, Markus
The twin arginine translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis. (2013)
Wagley, Sariqa; Hemsley, Claudia; Thomas, Rachael; Moule, Madeleine G; Vanaporn, Muthita; Andreae, Clio; Robinson, Matthew; Goldman, Stan; Wren, Brendan W; Butler, Clive S; Titball, Richard W
Invertebrates as a source of emerging human pathogens. (2004)
Waterfield, Nicholas R; Wren, Brendan W; Ffrench-Constant, Richard H
Shared characteristics between Mycobacterium tuberculosis and fungi contribute to virulence. (2014)
Willcocks, Sam; Wren, Brendan W
Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment. (2005)
Woodall, CA; Jones, MA; Barrow, PA; Hinds, J; Marsden, GL; Kelly, DJ; Dorrell, N; Wren, BW; Maskell, DJ
Clostridium difficile. (2001)
Wren, B
Innate immunity: past, present and future. (2005)
Wren, BW
Chameleonbacter jejuni - the changing sugar coat of a foodborne pathogen. (2001)
Wren, BW
How bacterial pathogens evolve. (2006)
Wren, BW
Methods in microbiology: functional microbial genomics. (2002)
Wren, BW; Dorrell, N. (Eds)
Post genome analysis of Campylobacter jejuni. (2001)
Wren, BW; Linton, D; Dorrell, N; Karlyshev, AV
Clostridium difficile comes of age. (2006)
Wren, Brendan W
The yersiniae--a model genus to study the rapid evolution of bacterial pathogens. (2003)
Wren, Brendan W
Deciphering tsetse's secret partner. (2002)
Wren, Brendan W
Characterization of enteropathogenic Escherichia coli of clinical origin from the pediatric population in Pakistan. (2016)
Younas, Mahwish; Siddiqui, Fariha; Noreen, Zobia; Bokhari, Syeda Sadia; Gomez-Duarte, Oscar G; Wren, Brendan W; Bokhari, Habib
Helicobacter pylori adherence to gastric epithelial cells: a role for non-adhesin virulence genes. (2002)
Zhang, Zun-Wu; Dorrell, Nick; Wren, Brendan W; Farthing, Michael JG
A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in mediating host bactericidal activity against Campylobacter jejuni. (2007)
Zilbauer, M; Dorrell, N; Elmi, A; Lindley, K; Klein, N; Nunez, G; Wren, B; Bajaj-Elliott, M
A major role for intestinal epithelial nucleotide oligomerization domain (NOD) protein NOD1 in mediating host bactericidal activity against Campylobacter jejuni. (2007)
Zilbauer, M; Dorrell, N; Elmi, A; Nunez, G; Klein, NJ; Wren, BW; Bajaj-Elliott, M
Intestinal innate immunity to Campylobacter jejuni results in induction of bactericidal human beta-defensins 2 and 3. (2005)
Zilbauer, Matthias; Dorrell, Nick; Boughan, Parjeet K; Harris, Andrew; Wren, Brendan W; Klein, Nigel J; Bajaj-Elliott, Mona
A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. (2007)
Zilbauer, Matthias; Dorrell, Nick; Elmi, Abdi; Lindley, Keith J; Schüller, Stephanie; Jones, Hannah E; Klein, Nigel J; Núnez, Gabriel; Wren, Brendan W; Bajaj-Elliott, Mona
A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. (2007)
Zilbauer, Matthias; Dorrell, Nick; Elmi, Abdi; Lindley, Keith J; Schüller, Stephanie; Jones, Hannah E; Klein, Nigel J; Núňez, Gabriel; Wren, Brendan W; Bajaj-Elliott, Mona
Campylobacter jejuni-mediated disease pathogenesis: an update. (2008)
Zilbauer, Matthias; Dorrell, Nick; Wren, Brendan W; Bajaj-Elliott, Mona
Public
December 2014 - Ebola, food poisoning, and a look back through the year. (2014)
UNSPECIFIED
Quantitative Analyses Reveal Novel Roles for N-Glycosylation in a Major Enteric Bacterial Pathogen. (2019)
Abouelhadid, Sherif; North, Simon J; Hitchen, Paul; Vohra, Prerna; Chintoan-Uta, Cosmin; Stevens, Mark; Dell, Anne; Cuccui, Jon; Wren, Brendan W
Characterization of Posttranslationally Modified Multidrug Efflux Pumps Reveals an Unexpected Link between Glycosylation and Antimicrobial Resistance. (2020)
Abouelhadid, Sherif; Raynes, John; Bui, Tam; Cuccui, Jon; Wren, Brendan W
The X-ray structure of L-threonine dehydrogenase from the common hospital pathogen Clostridium difficile. (2021)
Adjogatse, Eyram; Bennett, Josh; Guo, Jingxu; Erskine, Peter T; Wood, Steve P; Wren, Brendan W; Cooper, Jonathan B
YPTB3816 of Yersinia pseudotuberculosis strain IP32953 is a virulence-related metallo-oligopeptidase. (2016)
Atas, Ali; Seddon, Alan M; Ford, Donna C; Cooper, Ian A; Wren, Brendan W; Oyston, Petra CF; Karlyshev, Andrey V
Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. (2011)
Atkinson, Steve; Goldstone, Robert J; Joshua, George WP; Chang, Chien-Yi; Patrick, Hannah L; Cámara, Miguel; Wren, Brendan W; Williams, Paul
Whole genome investigation of a divergent clade of the pathogen Streptococcus suis. (2015)
Baig, Abiyad; Weinert, Lucy A; Peters, Sarah E; Howell, Kate J; Chaudhuri, Roy R; Wang, Jinhong; Holden, Matthew TG; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J
The importance of the glycosylation of antimicrobial peptides: natural and synthetic approaches. (2017)
Bednarska, Natalia G; Wren, Brendan W; Willcocks, Sam J
Galleria mellonella is low cost and suitable surrogate host for studying virulence of human pathogenic Vibrio cholerae. (2017)
Bokhari, Habib; Ali, Amjad; Noreen, Zobia; Thomson, Nicholas; Wren, Brendan W
Escherichia coli pathotypes in Pakistan from consecutive floods in 2010 and 2011. (2013)
Bokhari, Habib; Shah, Muhammad Ali; Asad, Saba; Akhtar, Sania; Akram, Muhammad; Wren, Brendan W
Proposal of serovars 17 and 18 of Actinobacillus pleuropneumoniae based on serological and genotypic analysis. (2018)
Bossé, JT; LI, Y; Sárközi, R; Fodor, L; Lacouture, S; Gottschalk, M; Amoribieta, MC; Angen, Ø; Nedbalcova, K; Holden, MT; Wren, B
Complete Genome Sequence of MIDG2331, a Genetically Tractable Serovar 8 Clinical Isolate of Actinobacillus pleuropneumoniae. (2016)
Bossé, Janine T; Chaudhuri, Roy R; Li, Yanwen; Leanse, Leon G; Fernandez Crespo, Roberto; Coupland, Paul; Holden, Matthew TG; Bazzolli, Denise M; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R
Multiplex PCR assay for unequivocal differentiation of Actinobacillus pleuropneumoniae serovars 1 to 3, 5 to 8, 10, and 12. (2014)
Bossé, Janine T; Li, Yanwen; Angen, Øystein; Weinert, Lucy A; Chaudhuri, Roy R; Holden, Matthew T; Williamson, Susanna M; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium
Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae. (2015)
Bossé, Janine T; Li, Yanwen; Atherton, Tom G; Walker, Stephanie; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium
Complete genome for Actinobacillus pleuropneumoniae serovar 8 reference strain 405: comparative analysis with draft genomes for different laboratory stock cultures indicates little genetic variation. (2021)
Bossé, Janine T; Li, Yanwen; Cohen, Liza Miriam; Stegger, Marc; Angen, Øystein; Lacouture, Sonia; Gottschalk, Marcelo; Lei, Liancheng; Koene, Miriam; Kuhnert, Peter; Bandara, Aloka B; Inzana, Thomas J; Holden, Matthew TG; Harris, David; Oshota, Olusegun; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; On Behalf Of The BRaDP T Consortium
Draft Genome Sequences of the Type Strains of Actinobacillus indolicus (46K2C) and Actinobacillus porcinus (NM319), Two NAD-Dependent Bacterial Species Found in the Respiratory Tract of Pigs. (2020)
Bossé, Janine T; Li, Yanwen; Fernandez Crespo, Roberto; Angen, Øystein; Holden, Matthew TG; Weinert, Lucy A; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium
ICEApl1, an Integrative Conjugative Element Related to ICEHin1056, Identified in the Pig Pathogen Actinobacillus pleuropneumoniae. (2016)
Bossé, Janine T; Li, Yanwen; Fernandez Crespo, Roberto; Chaudhuri, Roy R; Rogers, Jon; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; the BRaDP1T Consortium
Comparative sequence analysis of the capsular polysaccharide loci of Actinobacillus pleuropneumoniae serovars 1-18, and development of two multiplex PCRs for comprehensive capsule typing. (2018)
Bossé, Janine T; Li, Yanwen; Fernandez Crespo, Roberto; Lacouture, Sonia; Gottschalk, Marcelo; Sárközi, Rita; Fodor, László; Casas Amoribieta, Maria; Angen, Øystein; Nedbalcova, Katerina; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium
Rationally designed mariner vectors for functional genomic analysis of Actinobacillus pleuropneumoniae and other Pasteurellaceae species by transposon-directed insertion-site sequencing (TraDIS). (2021)
Bossé, Janine T; Li, Yanwen; Leanse, Leon G; Zhou, Liqing; Chaudhuri, Roy R; Peters, Sarah E; Wang, Jinhong; Maglennon, Gareth A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium
Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae. (2017)
Bossé, Janine T; Li, Yanwen; Rogers, Jon; Fernandez Crespo, Roberto; Li, Yinghui; Chaudhuri, Roy R; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R
Proposal of serovars 17 and 18 of Actinobacillus pleuropneumoniae based on serological and genotypic analysis. (2018)
Bossé, Janine T; Li, Yanwen; Sárközi, Rita; Fodor, László; Lacouture, Sonia; Gottschalk, Marcelo; Casas Amoribieta, Maria; Angen, Øystein; Nedbalcova, Katerina; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium
Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae. (2015)
Bossé, Janine T; Li, Yanwen; Walker, Stephanie; Atherton, Tom; Fernandez Crespo, Roberto; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Oshota, Olusegun; Holden, Matt TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T Consortium
The generation of successive unmarked mutations and chromosomal insertion of heterologous genes in Actinobacillus pleuropneumoniae using natural transformation. (2014)
Bossé, Janine T; Soares-Bazzolli, Denise M; Li, Yanwen; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J; Rycroft, Andrew N; Langford, Paul R; BRaDP1T Consortium
The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans. (2016)
Bouché, Laura; Panico, Maria; Hitchen, Paul; Binet, Daniel; Sastre, Federico; Faulds-Pain, Alexandra; Valiente, Esmeralda; Vinogradov, Evgeny; Aubry, Annie; Fulton, Kelly; Twine, Susan; Logan, Susan M; Wren, Brendan W; Dell, Anne; Morris, Howard R
Comparative Genomic Analysis and In Vivo Modeling of Streptococcus pneumoniae ST3081 and ST618 Isolates Reveal Key Genetic and Phenotypic Differences Contributing to Clonal Replacement of Serotype 1 in The Gambia. (2017)
Bricio-Moreno, Laura; Ebruke, Chinelo; Chaguza, Chrispin; Cornick, Jennifer; Kwambana-Adams, Brenda; Yang, Marie; Mackenzie, Grant; Wren, Brendan W; Everett, Dean; Antonio, Martin; Kadioglu, Aras
Use of Proteins Identified through a Functional Genomic Screen To Develop a Protein Subunit Vaccine That Provides Significant Protection against Virulent Streptococcus suis in Pigs. (2017)
Brockmeier, Susan L; Loving, Crystal L; Nicholson, Tracy L; Wang, Jinhong; Peters, Sarah E; Weinert, Lucy; Chaudhuri, Roy; Seilly, David J; Langford, Paul R; Rycroft, Andrew; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W
Development of anaerobic culturing methods to study the evolution and transmission of the human intestinal microbiota. (2018)
Browne, HP
Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages. (2016)
Cairns, MD; Preston, MD; Hall, CL; Gerding, DN; Hawkey, PM; Kato, H; Kim, H; Kuijper, EJ; Lawley, TD; Pituch, H; Reid, S; Kullin, B; Riley, TV; Solomon, K; Tsai, PJ; Weese, JS; Stabler, RA; Wren, BW
Genomic Epidemiology of a Protracted Hospital Outbreak Caused by a Toxin A-Negative Clostridium difficile Sublineage PCR Ribotype 017 Strain in London, England. (2015)
Cairns, MD; Preston, MD; Lawley, TD; Clark, TG; Stabler, RA; Wren, BW
An investigation into the genetic diversity of the food-borne pathogen campylobacter jejuni using DNA microarrays. (2005)
Champion, Olivia Lucy
Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge. (2010)
Commander, Nicola J; Brewer, James M; Wren, Brendan W; Spencer, Stephen A; Macmillan, Alastair P; Stack, Judith A
Virulence characteristics of hcp (+) Campylobacter jejuni and Campylobacter coli isolates from retail chicken. (2015)
Corcionivoschi, Nicolae; Gundogdu, Ozan; Moran, Lynn; Kelly, Carmel; Scates, Pam; Stef, Lavinia; Cean, Ada; Wren, Brendan; Dorrell, Nick; Madden, Robert H
Serovar-dependent differences in Hfq-regulated phenotypes in Actinobacillus pleuropneumoniae. (2020)
Crispim, Josicelli Souza; da Silva, Thyara Ferreira; Sanches, Newton Moreno; da Silva, Giarlã Cunha; Pereira, Monalessa Fábia; Rossi, Ciro César; Li, Yanwen; Terra, Vanessa Sofia; Vohra, Prerna; Wren, Brendan W; Langford, Paul R; Bossé, Janine T; Bazzolli, Denise Mara Soares
The N-linking glycosylation system from Actinobacillus pleuropneumoniae is required for adhesion and has potential use in glycoengineering. (2016)
Cuccui, Jon; Terra, Vanessa S; Bossé, Janine T; Naegeli, Andreas; Abouelhadid, Sherif; Li, Yanwen; Lin, Chia-Wei; Vohra, Prerna; Tucker, Alexander W; Rycroft, Andrew N; Maskell, Duncan J; Aebi, Markus; Langford, Paul R; Wren, Brendan W; BRaDP1T Consortium
Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis. (2013)
Cuccui, Jon; Thomas, Rebecca M; Moule, Madeleine G; D'Elia, Riccardo V; Laws, Thomas R; Mills, Dominic C; Williamson, Diane; Atkins, Timothy P; Prior, Joann L; Wren, Brendan W
Hijacking bacterial glycosylation for the production of glycoconjugates, from vaccines to humanised glycoproteins. (2014)
Cuccui, Jon; Wren, Brendan
Sodium Taurocholate Stimulates Campylobacter jejuni Outer Membrane Vesicle Production via Down-Regulation of the Maintenance of Lipid Asymmetry Pathway. (2019)
Davies, Cadi; Taylor, Aidan J; Elmi, Abdi; Winter, Jody; Liaw, Janie; Grabowska, Anna D; Gundogdu, Ozan; Wren, Brendan W; Kelly, David J; Dorrell, Nick
The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains. (2011)
Dawson, Lisa F; Donahue, Elizabeth H; Cartman, Stephen T; Barton, Richard H; Bundy, Jake; McNerney, Ruth; Minton, Nigel P; Wren, Brendan W
Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile. (2021)
Dawson, Lisa F; Peltier, Johann; Hall, Catherine L; Harrison, Mark A; Derakhshan, Maria; Shaw, Helen A; Fairweather, Neil F; Wren, Brendan W
Hypervirulent Clostridium difficile PCR-ribotypes exhibit resistance to widely used disinfectants. (2011)
Dawson, Lisa F; Valiente, Esmeralda; Donahue, Elizabeth H; Birchenough, George; Wren, Brendan W
Characterisation of Clostridium difficile biofilm formation, a role for Spo0A. (2012)
Dawson, Lisa F; Valiente, Esmeralda; Faulds-Pain, Alexandra; Donahue, Elizabeth H; Wren, Brendan W
Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores. (2013)
Dembek, Marcin; Stabler, Richard A; Witney, Adam A; Wren, Brendan W; Fairweather, Neil F
Clinical Issues and Molecular Characterisation of Salmonella Typhi Isolates from South East Asia. (2011)
Dolecek, C
Investigating the roles of the cell wall anchoring
sortase enzyme and sorted proteins in
Clostridium difficile. (2015)
Donahue, EH
Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. (2014)
Donahue, Elizabeth H; Dawson, Lisa F; Valiente, Esmeralda; Firth-Clark, Stuart; Major, Meriel R; Littler, Eddy; Perrior, Trevor R; Wren, Brendan W
High levels of recombination among Streptococcus pneumoniae isolates from the Gambia. (2011)
Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP
High Levels of Recombination among Streptococcus pneumoniae Isolates from the Gambia - corrections to earlier article. (2011)
Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP
High Levels of Recombination among Streptococcus pneumoniae Isolates from the Gambia. (2011)
Donkor, ES; Bishop, CJ; Gould, KA; Hinds, J; Antonio, M; Wren, B; Hanage, WP
Population biology of Streptococcus pneumoniae in West Africa: multilocus sequence typing of serotypes that exhibit different predisposition to invasive disease and carriage. (2013)
Donkor, Eric S; Adegbola, Richard A; Wren, Brendan W; Antonio, Martin
Comparative phylogenomics of Streptococcus pneumoniae isolated from invasive disease and nasopharyngeal carriage from West Africans. (2012)
Donkor, Eric S; Stabler, Richard A; Hinds, Jason; Adegbola, Richard A; Antonio, Martin; Wren, Brendan W
Microarray analysis of campylobacter jejuni: to the guts of the problem! (2002)
Dorrell, Nick; Champion, Olivia L; Wren, Brendan W
Generation and Evaluation of a Glaesserella (Haemophilus) parasuis Capsular Mutant. (2020)
Eberle, Kirsten C; Hau, Samantha J; Luan, Shi-Lu; Weinert, Lucy A; Stasko, Judith A; Wang, Jinhong; Peters, Sarah E; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W; Brockmeier, Susan L
Molecular epidemiological and pathogenesis studies of Streptococcus pneumoniae serotype 1 strains from West Africa. (2018)
Ebruke, CN
Temporal changes in nasopharyngeal carriage of Streptococcus pneumoniae serotype 1 genotypes in healthy Gambians before and after the 7-valent pneumococcal conjugate vaccine. (2015)
Ebruke, Chinelo; Roca, Anna; Egere, Uzochukwu; Darboe, Ousainou; Hill, Philip C; Greenwood, Brian; Wren, Brendan W; Adegbola, Richard A; Antonio, Martin
Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection. (2010)
Edwards, Lindsey A; Nistala, Kiran; Mills, Dominic C; Stephenson, Holly N; Zilbauer, Matthias; Wren, Brendan W; Dorrell, Nick; Lindley, Keith J; Wedderburn, Lucy R; Bajaj-Elliott, Mona
The bile salt sodium taurocholate induces Campylobacter jejuni outer membrane vesicle production and increases OMV-associated proteolytic activity. (2017)
Elmi, Abdi; Dorey, Amber; Watson, Eleanor; Jagatia, Heena; Inglis, Neil F; Gundogdu, Ozan; Bajaj-Elliott, Mona; Wren, Brendan W; Smith, David GE; Dorrell, Nick
Revisiting Campylobacter jejuni Virulence and Fitness Factors: Role in Sensing, Adapting, and Competing. (2021)
Elmi, Abdi; Nasher, Fauzy; Dorrell, Nick; Wren, Brendan; Gundogdu, Ozan
Campylobacter jejuni outer membrane vesicle-associated proteolytic activity promotes bacterial invasion by mediating cleavage of intestinal epithelial cell E-cadherin and occludin. (2015)
Elmi, Abdi; Nasher, Fauzy; Jagatia, Heena; Gundogdu, Ozan; Bajaj-Elliott, Mona; Wren, Brendan; Dorrell, Nick
Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. (2012)
Elmi, Abdi; Watson, Eleanor; Sandu, Pamela; Gundogdu, Ozan; Mills, Dominic C; Inglis, Neil F; Manson, Erin; Imrie, Lisa; Bajaj-Elliott, Mona; Wren, Brendan W; Smith, David GE; Dorrell, Nick
The Streptococcos suis sortases SrtB and SrtF are essential for disease in pigs. (2018)
Faulds-Pain, Alexandra; Shaw, Helen Alexandra; Terra, Vanessa Sofia; Kellner, Steven; Brockmeier, Susan L; Wren, Brendan W
The post-translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence. (2014)
Faulds-Pain, Alexandra; Twine, Susan M; Vinogradov, Evgeny; Strong, Philippa CR; Dell, Anne; Buckley, Anthony M; Douce, Gillian R; Valiente, Esmeralda; Logan, Susan M; Wren, Brendan W
Improved bacterial mutagenesis by high-frequency allele exchange, demonstrated in Clostridium difficile and Streptococcus suis. (2013)
Faulds-Pain, Alexandra; Wren, Brendan W
Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits. (2020)
Faulkner, Valwynne; Cox, Adrienne Adele; Goh, Shan; van Bohemen, Annelies; Gibson, Amanda J; Liebster, Oliver; Wren, Brendan W; Willcocks, Sam; Kendall, Sharon L
Probing Differences in Gene Essentiality Between the Human and Animal Adapted Lineages of the Mycobacterium tuberculosis Complex Using TnSeq. (2021)
Gibson, Amanda J; Passmore, Ian J; Faulkner, Valwynne; Xia, Dong; Nobeli, Irene; Stiens, Jennifer; Willcocks, Sam; Clark, Taane G; Sobkowiak, Ben; Werling, Dirk; Villarreal-Ramos, Bernardo; Wren, Brendan W; Kendall, Sharon L
Defining the Genes Required for Survival of Mycobacterium bovis in the Bovine Host Offers Novel Insights into the Genetic Basis of Survival of Pathogenic Mycobacteria. (2022)
Gibson, Amanda J; Stiens, Jennifer; Passmore, Ian J; Faulkner, Valwynne; Miculob, Josephous; Willcocks, Sam; Coad, Michael; Berg, Stefan; Werling, Dirk; Wren, Brendan W; Nobeli, Irene; Villarreal-Ramos, Bernardo; Kendall, Sharon L
Environmental interactions are regulated by temperature in Burkholderia seminalis TC3.4.2R3. (2019)
Gonçalves, Priscila Jane Romano de Oliveira; Hume, Carmen C Denman; Ferreira, Almir José; Tsui, Sarina; Brocchi, Marcelo; Wren, Brendan W; Araujo, Welington Luiz
Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence. (2007)
Gundogdu, Ozan; Bentley, Stephen D; Holden, Matt T; Parkhill, Julian; Dorrell, Nick; Wren, Brendan W
The Campylobacter jejuni transcriptional regulator Cj1556 plays a role in the oxidative and aerobic stress response and is important for bacterial survival in vivo. (2011)
Gundogdu, Ozan; Mills, Dominic C; Elmi, Abdi; Martin, Melissa J; Wren, Brendan W; Dorrell, Nick
Microbe Profile: Campylobacter jejuni - survival instincts. (2020)
Gundogdu, Ozan; Wren, Brendan W
The Campylobacter jejuni MarR-like transcriptional regulators RrpA and RrpB both influence bacterial responses to oxidative and aerobic stresses. (2015)
Gundogdu, Ozan; da Silva, Daiani T; Mohammad, Banaz; Elmi, Abdi; Mills, Dominic C; Wren, Brendan W; Dorrell, Nick
The Campylobacter jejuni Oxidative Stress Regulator RrpB Is Associated with a Genomic Hypervariable Region and Altered Oxidative Stress Resistance. (2016)
Gundogdu, Ozan; da Silva, Daiani T; Mohammad, Banaz; Elmi, Abdi; Wren, Brendan W; van Vliet, Arnoud HM; Dorrell, Nick
Investigating novel vaccine candidates for Clostridium difficile. (2020)
Hall, C
Surveillance and diagnosis of plague and anthrax in Tanzania and Zambia. (2014)
Hang'ombe, BM; Ziwa, M; Haule, M; Nakamura, I; Samui, KL; Kaile, D; Mweene, AS; Kilonzo, BS; Lyamuya, EF; Matee, M; Sugimoto, C; Sawa, H; Wren, BW
Evidence of Yersinia pestis DNA from fleas in an endemic plague area of Zambia. (2012)
Hang'ombe, Bernard M; Nakamura, Ichiro; Samui, Kenny L; Kaile, Davy; Mweene, Aaron S; Kilonzo, Bukheti S; Sawa, Hirofumi; Sugimoto, Chihiro; Wren, Brendan W
Identification of the plague reservoir in an endemic area of Zambia. (2012)
Hang’ombe, Bernard M; Nakamura, I; Kaile, D; Mweene, AS; Samui, KL; Kilonzo, BS; Sawa, H; Sugimoto, C; Wren, B
Identification of possible virulence marker from Campylobacter jejuni isolates. (2014)
Harrison, James W; Dung, Tran Thi Ngoc; Siddiqui, Fariha; Korbrisate, Sunee; Bukhari, Habib; Tra, My Phan Vu; Hoang, Nguyen Van Minh; Carrique-Mas, Juan; Bryant, Juliet; Campbell, James I; Studholme, David J; Wren, Brendan W; Baker, Stephen; Titball, Richard W; Champion, Olivia L
Characterising regulation of virulence factors affecting the interaction between Clostridioides difficile and the intestinal microbiome. (2022)
Harrison, MA
Clostridioides difficile para-Cresol Production Is Induced by the Precursor para-Hydroxyphenylacetate. (2020)
Harrison, Mark A; Faulds-Pain, Alexandra; Kaur, Harparkash; Dupuy, Bruno; Henriques, Adriano O; Martin-Verstraete, Isabelle; Wren, Brendan W; Dawson, Lisa F
Clostridioides difficile para-Cresol Production Is Induced by the Precursor para-Hydroxyphenylacetate. (2020)
Harrison, Mark A; Faulds-Pain, Alexandra; Kaur, Harparkash; Dupuy, Bruno; Henriques, Adriano O; Martin-Verstraete, Isabelle; Wren, Brendan W; Dawson, Lisa F
Production of p-cresol by Decarboxylation of p-HPA by All Five Lineages of Clostridioides difficile Provides a Growth Advantage.
Harrison, Mark A; Kaur, Harparkash; Wren, Brendan W; Dawson, Lisa F
Evaluation of the recombinant proteins RlpB and VacJ as a vaccine for protection against Glaesserella parasuis in pigs. (2020)
Hau, Samantha J; Luan, Shi-Lu; Loving, Crystal L; Nicholson, Tracy L; Wang, Jinhong; Peters, Sarah E; Seilly, David; Weinert, Lucy A; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W; Brockmeier, Susan L; BRaDP1T Consortium
Emergence and global spread of epidemic healthcare-associated Clostridium difficile. (2012)
He, Miao; Miyajima, Fabio; Roberts, Paul; Ellison, Louise; Pickard, Derek J; Martin, Melissa J; Connor, Thomas R; Harris, Simon R; Fairley, Derek; Bamford, Kathleen B; D'Arc, Stephanie; Brazier, Jon; Brown, Derek; Coia, John E; Douce, Gill; Gerding, Dale; Kim, Hee Jung; Koh, Tse Hsien; Kato, Haru; Senoh, Mitsutoshi; Louie, Tom; Michell, Stephen; Butt, Emma; Peacock, Sharon J; Brown, Nick M; Riley, Tom; Songer, Glen; Wilcox, Mark; Pirmohamed, Munir; Kuijper, Ed; Hawkey, Peter; Wren, Brendan W; Dougan, Gordon; Parkhill, Julian; Lawley, Trevor D
Genomic variations define divergence of water/wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes. (2011)
Hepworth, Philip J; Ashelford, Kevin E; Hinds, Jason; Gould, Katherine A; Witney, Adam A; Williams, Nicola J; Leatherbarrow, Howard; French, Nigel P; Birtles, Richard J; Mendonca, Chriselle; Dorrell, Nick; Wren, Brendan W; Wigley, Paul; Hall, Neil; Winstanley, Craig
Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine. (2018)
Herbert, Jenny A; Kay, Emily J; Faustini, Sian E; Richter, Alex; Abouelhadid, Sherif; Cuccui, Jon; Wren, Brendan; Mitchell, Timothy J
Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014. (2017)
Hernandez-Garcia, Juan; Wang, Jinhong; Restif, Olivier; Holmes, Mark A; Mather, Alison E; Weinert, Lucy A; Wileman, Thomas M; Thomson, Jill R; Langford, Paul R; Wren, Brendan W; Rycroft, Andrew; Maskell, Duncan J; Tucker, Alexander W; BRADP1T Consortium
Separated at birth? Microarray analysis of two strikingly similar yersinia species. (2002)
Hinchliffe, SJ; Isherwood, KE; Stabler, RA; Oyston, PCF; Hinds, J; Titbal, RW; Wren, BW
Campylobacter jejuni Modulates Reactive Oxygen Species Production and NADPH Oxidase 1 Expression in Human Intestinal Epithelial Cells. (2023)
Hong, Geunhye; Davies, Cadi; Omole, Zahra; Liaw, Janie; Grabowska, Anna D; Canonico, Barbara; Corcionivoschi, Nicolae; Wren, Brendan W; Dorrell, Nick; Elmi, Abdi; Gundogdu, Ozan
Campylobacter jejuni modulates reactive oxygen species production and NADPH oxidase 1 expression in human intestinal epithelial cells. (2022)
Hong, geung; Davies, cadi; Omole, zahra; Liaw, janie; grabowska, anna; Canonico, barbara; corcionivoschi, Nicolae; Wren, brendan; Dorrell, nick; Elmi, abdi; Gundogdu, Ozan
"Pathotyping" Multiplex PCR Assay for Haemophilus parasuis: a Tool for Prediction of Virulence. (2017)
Howell, Kate J; Weinert, Lucy A; Peters, Sarah E; Wang, Jinhong; Hernandez-Garcia, Juan; Chaudhuri, Roy R; Luan, Shi-Lu; Angen, Øystein; Aragon, Virginia; Williamson, Susanna M; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W
Comprehensive Longitudinal Microbiome Analysis of the Chicken Cecum Reveals a Shift From Competitive to Environmental Drivers and a Window of Opportunity for Campylobacter. (2018)
Ijaz, Umer Zeeshan; Sivaloganathan, Lojika; McKenna, Aaron; Richmond, Anne; Kelly, Carmel; Linton, Mark; Stratakos, Alexandros Ch; Lavery, Ursula; Elmi, Abdi; Wren, Brendan W; Dorrell, Nick; Corcionivoschi, Nicolae; Gundogdu, Ozan
Comprehensive longitudinal microbiome analysis of the chicken cecum reveals a shift from competitive to environmental drivers and a window of opportunity for <i>Campylobacter</i>. (2018)
Ijaz, Umer Zeeshan; Sivaloganathan, Lojika; Mckenna, Aaron; Richmond, Anne; Kelly, Carmel; Linton, Mark; Stratakos, Alexandros; Lavery, Ursula; Elmi, Abdi; Wren, Brendan; Dorrell, Nick; Corcionivoschi, Nicolae; Gundogdu, Ozan
Chromosomal integration vectors allowing flexible expression of foreign genes in Campylobacter jejuni. (2015)
Jervis, Adrian J; Butler, Jonathan A; Wren, Brendan W; Linton, Dennis
Functional analysis of the Helicobacter pullorum N-linked protein glycosylation system. (2018)
Jervis, Adrian J; Wood, Alison G; Cain, Joel A; Butler, Jonathan A; Frost, Helen; Lord, Elizabeth; Langdon, Rebecca; Cordwell, Stuart J; Wren, Brendan W; Linton, Dennis
Pancreatic amylase is an environmental signal for regulation of biofilm formation and host interaction in Campylobacter jejuni. (2015)
Jowiya, Waheed; Brunner, Katja; Abouelhadid, Sherif; Hussain, Haitham A; Nair, Sean P; Sadiq, Sohaib; Williams, Lisa K; Trantham, Emma K; Stephenson, Holly; Wren, Brendan W; Bajaj-Elliott, Mona; Cogan, Tristan A; Laws, Andrew P; Wade, Jim; Dorrell, Nick; Allan, Elaine
Strain Specific Variations in Acinetobacter baumannii Complement Sensitivity. (2022)
Kamuyu, Gathoni; Ercoli, Giuseppe; Ramos-Sevillano, Elisa; Willcocks, Sam; Kewcharoenwong, Chidchamai; Kiratisin, Pattarachai; Taylor, Peter W; Wren, Brendan W; Lertmemongkolchai, Ganjana; Stabler, Richard A; Brown, Jeremy S
Sequential Vaccination With Heterologous Acinetobacter baumannii Strains Induces Broadly Reactive Antibody Responses. (2021)
Kamuyu, Gathoni; Suen Cheng, Yat; Willcocks, Sam; Kewcharoenwong, Chidchamai; Kiratisin, Pattarachai; Taylor, Peter W; Wren, Brendan W; Lertmemongkolchai, Ganjana; Stabler, Richard A; Brown, Jeremy
Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation. (2014)
Karlyshev, AV; Thacker, G; Jones, MA; Clements, MO; Wren, BW
Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines. (2022)
Kay, Emily J; Mauri, Marta; Willcocks, Sam J; Scott, Timothy A; Cuccui, Jon; Wren, Brendan W
Recombinant expression of Streptococcus pneumoniae capsular polysaccharides in Escherichia coli. (2016)
Kay, Emily J; Yates, Laura E; Terra, Vanessa S; Cuccui, Jon; Wren, Brendan W
Recent advances in the production of recombinant glycoconjugate vaccines. (2019)
Kay, Emily; Cuccui, Jon; Wren, Brendan W
The In Vitro and In Vivo Effect of Carvacrol in Preventing Campylobacter Infection, Colonization and in Improving Productivity of Chicken Broilers. (2017)
Kelly, C; Gundogdu, O; Pircalabioru, G; Cean, A; Scates, P; Linton, M; Pinkerton, L; Magowan, E; Stef, L; Simiz, E; Pet, I; Stewart, S; Stabler, R; Wren, B; Dorrell, N; Corcionivoschi, N
Zoonotic Transfer of Clostridium difficile Harboring Antimicrobial Resistance between Farm Animals and Humans. (2017)
Knetsch, CW; Kumar, N; Forster, SC; Connor, TR; Browne, HP; Harmanus, C; Sanders, IM; Harris, SR; Turner, L; Morris, T; Perry, M; Miyajima, F; Roberts, P; Pirmohamed, M; Songer, JG; Weese, JS; Indra, A; Corver, J; Rupnik, M; Wren, BW; Riley, TV; Kuijper, EJ; Lawley, TD
Adaptation of host transmission cycle during Clostridium difficile speciation. (2019)
Kumar, Nitin; Browne, Hilary P; Viciani, Elisa; Forster, Samuel C; Clare, Simon; Harcourt, Katherine; Stares, Mark D; Dougan, Gordon; Fairley, Derek J; Roberts, Paul; Pirmohamed, Munir; Clokie, Martha RJ; Jensen, Mie Birgitte Frid; Hargreaves, Katherine R; Ip, Margaret; Wieler, Lothar H; Seyboldt, Christian; Norén, Torbjörn; Riley, Thomas V; Kuijper, Ed J; Wren, Brendan W; Lawley, Trevor D
Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence. (2015)
Kumar, Nitin; Miyajima, Fabio; He, Miao; Roberts, Paul; Swale, Andrew; Ellison, Louise; Pickard, Derek; Smith, Godfrey; Molyneux, Rebecca; Dougan, Gordon; Parkhill, Julian; Wren, Brendan W; Parry, Christopher M; Pirmohamed, Munir; Lawley, Trevor D
Actinobacillus pleuropneumoniae serovar 8 predominates in England and Wales. (2016)
Li, Y; Bossé, JT; Williamson, SM; Maskell, DJ; Tucker, AW; Wren, BW; Rycroft, AN; Langford, PR; BRADP1T Consortium
The Campylobacter jejuni Type VI Secretion System Enhances the Oxidative Stress Response and Host Colonization. (2019)
Liaw, Janie; Hong, Geunhye; Davies, Cadi; Elmi, Abdi; Sima, Filip; Stratakos, Alexandros; Stef, Lavinia; Pet, Ioan; Hachani, Abderrahman; Corcionivoschi, Nicolae; Wren, Brendan W; Gundogdu, Ozan; Dorrell, Nick
The characterization of the lipoprotein VacJ in Burkholderia
pseudomallei and Burkholderia thailandensis. (2015)
Lim, J
Understanding and managing zoonotic risk in the new livestock industries. (2013)
Liverani, Marco; Waage, Jeff; Barnett, Tony; Pfeiffer, Dirk U; Rushton, Jonathan; Rudge, James W; Loevinsohn, Michael E; Scoones, Ian; Smith, Richard D; Cooper, Ben S; White, Lisa J; Goh, Shan; Horby, Peter; Wren, Brendan; Gundogdu, Ozan; Woods, Abigail; Coker, Richard J
Draft Genome Sequence of Campylobacter jejuni 11168H. (2017)
Macdonald, Sarah E; Gundogdu, Ozan; Dorrell, Nick; Wren, Brendan W; Blake, Damer; Stabler, Richard
Transposon mutagenesis in Mycoplasma hyopneumoniae using a novel mariner-based system for generating random mutations. (2013)
Maglennon, Gareth A; Cook, Beth S; Deeney, Alannah S; Bossé, Janine T; Peters, Sarah E; Langford, Paul R; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; BRaDP1T consortium
Development of a self-replicating plasmid system for Mycoplasma hyopneumoniae. (2013)
Maglennon, Gareth A; Cook, Beth S; Matthews, Dominic; Deeney, Alannah S; Bossé, Janine T; Langford, Paul R; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; BRaDP1T consortium
Use of Precision-Cut Tissue Slices as a Translational Model to Study Host-Pathogen Interaction. (2021)
Majorova, Dominika; Atkins, Elizabeth; Martineau, Henny; Vokral, Ivan; Oosterhuis, Dorenda; Olinga, Peter; Wren, Brendan; Cuccui, Jon; Werling, Dirk
The phylogenetic and phenotypic analysis of Salmonella enterica serovar Weltevreden. (2016)
Makendi Njock, EC
A Phylogenetic and Phenotypic Analysis of Salmonella enterica Serovar Weltevreden, an Emerging Agent of Diarrheal Disease in Tropical Regions. (2016)
Makendi, Carine; Page, Andrew J; Wren, Brendan W; Le Thi Phuong, Tu; Clare, Simon; Hale, Christine; Goulding, David; Klemm, Elizabeth J; Pickard, Derek; Okoro, Chinyere; Hunt, Martin; Thompson, Corinne N; Phu Huong Lan, Nguyen; Tran Do Hoang, Nhu; Thwaites, Guy E; Le Hello, Simon; Brisabois, Anne; Weill, François-Xavier; Baker, Stephen; Dougan, Gordon
An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia. (2018)
Marshall, Laura E; Nelson, Michelle; Davies, Carwyn H; Whelan, Adam O; Jenner, Dominic C; Moule, Madeleine G; Denman, Carmen; Cuccui, Jon; Atkins, Timothy P; Wren, Brendan W; Prior, Joann L
The agr locus regulates virulence and colonization genes in Clostridium difficile 027. (2013)
Martin, Melissa J; Clare, Simon; Goulding, David; Faulds-Pain, Alexandra; Barquist, Lars; Browne, Hilary P; Pettit, Laura; Dougan, Gordon; Lawley, Trevor D; Wren, Brendan W
Multivalent poultry vaccine development using Protein Glycan Coupling Technology. (2021)
Mauri, Marta; Sannasiddappa, Thippeswamy H; Vohra, Prerna; Corona-Torres, Ricardo; Smith, Alexander A; Chintoan-Uta, Cosmin; Bremner, Abi; Terra, Vanessa S; Abouelhadid, Sherif; Stevens, Mark P; Grant, Andrew J; Cuccui, Jon; Wren, Brendan W; Glycoengineering of Veterinary Vaccines Consortium
Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter. (2020)
McKenna, Aaron; Ijaz, Umer Zeeshan; Kelly, Carmel; Linton, Mark; Sloan, William T; Green, Brian D; Lavery, Ursula; Dorrell, Nick; Wren, Brendan W; Richmond, Anne; Corcionivoschi, Nicolae; Gundogdu, Ozan
Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter. (2020)
McKenna, Aaron; Ijaz, Umer Zeeshan; Kelly, Carmel; Linton, Mark; Sloan, William T; Green, Brian D; Lavery, Ursula; Dorrell, Nick; Wren, Brendan W; Richmond, Anne; Corcionivoschi, Nicolae; Gundogdu, Ozan
Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce <i>Campylobacter</i>. (2020)
McKenna, Aaron; Ijaz, Umer Zeeshan; Kelly, Carmel; Linton, Mark; Sloan, William; Green, Brian; Lavery, Ursula; Dorrell, Nick; Wren, Brendan; Richmond, Anne; Corcionivoschi, Nicolae; Gundogdu, Ozan
Profiling of Haemophilus influenzae strain R2866 with carbohydrate-based covalent probes. (2021)
Metier, Camille; Dow, Jennifer; Wootton, Hayley; Lynham, Steven; Wren, Brendan; Wagner, Gerd K
Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment. (2012)
Mills, Dominic C; Gundogdu, Ozan; Elmi, Abdi; Bajaj-Elliott, Mona; Taylor, Peter W; Wren, Brendan W; Dorrell, Nick
Functional analysis of N-linking oligosaccharyl transferase enzymes encoded by deep-sea vent proteobacteria. (2015)
Mills, Dominic C; Jervis, Adrian J; Abouelhadid, Sherif; Yates, Laura E; Cuccui, Jon; Linton, Dennis; Wren, Brendan W
Clostridium perfringens epsilon toxin vaccine candidate lacking toxicity to cells expressing myelin and lymphocyte protein. (2019)
Morcrette, Helen; Bokori-Brown, Monika; Ong, Stephanie; Bennett, Leo; Wren, Brendan W; Lewis, Nick; Titball, Richard W
Infection Susceptibility in Gastric Intrinsic Factor (Vitamin B12)-Defective Mice Is Subject to Maternal Influences. (2016)
Mottram, Lynda; Speak, Anneliese O; Selek, Reza M; Cambridge, Emma L; McIntyre, Zoe; Kane, Leanne; Mukhopadhyay, Subhankar; Grove, Carolyn; Colin, Amy; Brandt, Cordelia; Duque-Correa, Maria A; Forbester, Jessica; Nguyen, Tu Anh Pham; Hale, Christine; Vasilliou, George S; Arends, Mark J; Wren, Brendan W; Dougan, Gordon; Clare, Simon
Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. (2014)
Moule, Madeleine G; Hemsley, Claudia M; Seet, Qihui; Guerra-Assunção, José Afonso; Lim, Jiali; Sarkar-Tyson, Mitali; Clark, Taane G; Tan, Patrick BO; Titball, Richard W; Cuccui, Jon; Wren, Brendan W
Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei. (2015)
Moule, Madeleine G; Spink, Natasha; Willcocks, Sam; Lim, Jiali; Guerra-Assunção, José Afonso; Cia, Felipe; Champion, Olivia L; Senior, Nicola J; Atkins, Helen S; Clark, Taane; Bancroft, Gregory J; Cuccui, Jon; Wren, Brendan W
The Antimicrobial Peptide, Bactenecin 5, Supports Cell-Mediated but Not Humoral Immunity in the Context of a Mycobacterial Antigen Vaccine Model. (2020)
Munshi, Tulika; Sparrow, Adam; Wren, Brendan W; Reljic, Rajko; Willcocks, Samuel J
Survival of Campylobacter jejuni 11168H in Acanthamoebae castellanii Provides Mechanistic Insight into Host Pathogen Interactions. (2022)
Nasher, Fauzy; Lehri, Burhan; Horney, Megan F; Stabler, Richard A; Wren, Brendan W
MdaB and NfrA, Two Novel Reductases Important in the Survival and Persistence of the Major Enteropathogen Campylobacter jejuni. (2021)
Nasher, Fauzy; Taylor, Aidan J; Elmi, Abdi; Lehri, Burhan; Ijaz, Umer Z; Baker, Dave; Goram, Richard; Lynham, Steven; Singh, Dipali; Stabler, Richard; Kelly, David J; Gundogdu, Ozan; Wren, Brendan W
Transient internalization of Campylobacter jejuni in Amoebae enhances subsequent invasion of human cells. (2022)
Nasher, Fauzy; Wren, Brendan W
The sudden dominance of blaCTX-M harbouring plasmids in Shigella spp. Circulating in Southern Vietnam. (2010)
Nguyen, Nhu Thi Khanh; Ha, Vinh; Tran, Nga Vu Thieu; Stabler, Richard; Pham, Duy Thanh; Le, Thi Minh Vien; van Doorn, H Rogier; Cerdeño-Tárraga, Ana; Thomson, Nicholas; Campbell, James; Nguyen, Van Minh Hoang; Tran, Thi Thu Nga; Pham, Minh Van; Cao, Thuy Thu; Wren, Brendan; Farrar, Jeremy; Baker, Stephen
Acinetobacter nosocomialis Causes as Severe Disease as Acinetobacter baumannii in Northeast Thailand: Underestimated Role of A. nosocomialis in Infection. (2022)
Nithichanon, Arnone; Kewcharoenwong, Chidchamai; Da-Oh, Hudadini; Surajinda, Sirithorn; Khongmee, Aranya; Koosakunwat, Surathinee; Wren, Brendan W; Stabler, Richard A; Brown, Jeremy S; Lertmemongkolchai, Ganjana
Transmission of multidrug-resistant Campylobacter jejuni to children from different sources in Pakistan. (2019)
Noreen, Zobia; Siddiqui, Fariha; Javed, Sundus; Wren, Brendan W; Bokhari, Habib
Genome sequence of Yersinia pestis, the causative agent of plague. (2001)
Parkhill, J; Wren, BW; Thomson, NR; Titball, RW; Holden, MT; Prentice, MB; Sebaihia, M; James, KD; Churcher, C; Mungall, KL; Baker, S; Basham, D; Bentley, SD; Brooks, K; Cerdeño-Tárraga, AM; Chillingworth, T; Cronin, A; Davies, RM; Davis, P; Dougan, G; Feltwell, T; Hamlin, N; Holroyd, S; Jagels, K; Karlyshev, AV; Leather, S; Moule, S; Oyston, PC; Quail, M; Rutherford, K; Simmonds, M; Skelton, J; Stevens, K; Whitehead, S; Barrell, BG
Bacterial epidemiology and biology--lessons from genome sequencing. (2011)
Parkhill, Julian; Wren, Brendan W
Domestication of Campylobacter jejuni NCTC 11168. (2019)
Pascoe, Ben; Williams, Lisa K; Calland, Jessica K; Meric, Guillaume; Hitchings, Matthew D; Dyer, Myles; Ryder, Joseph; Shaw, Sophie; Lopes, Bruno S; Chintoan-Uta, Cosmin; Allan, Elaine; Vidal, Ana; Fearnley, Catherine; Everest, Paul; Pachebat, Justin A; Cogan, Tristan A; Stevens, Mark P; Humphrey, Thomas J; Wilkinson, Thomas S; Cody, Alison J; Colles, Frances M; Jolley, Keith A; Maiden, Martin CJ; Strachan, Norval; Pearson, Bruce M; Linton, Dennis; Wren, Brendan W; Parkhill, Julian; Kelly, David J; van Vliet, Arnoud HM; Forbes, Ken J; Sheppard, Samuel K
Cytoplasmic glycoengineering of Apx toxin fragments in the development of Actinobacillus pleuropneumoniae glycoconjugate vaccines. (2019)
Passmore, Ian J; Andrejeva, Anna; Wren, Brendan W; Cuccui, Jon
Ferric Citrate Regulator FecR Is Translocated across the Bacterial Inner Membrane via a Unique Twin-Arginine Transport-Dependent Mechanism. (2020)
Passmore, Ian J; Dow, Jennifer M; Coll, Francesc; Cuccui, Jon; Palmer, Tracy; Wren, Brendan W
A combinatorial DNA assembly approach to biosynthesis of N-linked glycans in E. coli. (2023)
Passmore, Ian J; Faulds-Pain, Alexandra; Abouelhadid, Sherif; Harrison, Mark A; Hall, Catherine L; Hitchen, Paul; Dell, Anne; Heap, John T; Wren, Brendan W
Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria. (2018)
Passmore, Ian J; Letertre, Marine PM; Preston, Mark D; Bianconi, Irene; Harrison, Mark A; Nasher, Fauzy; Kaur, Harparkash; Hong, Huynh A; Baines, Simon D; Cutting, Simon M; Swann, Jonathan R; Wren, Brendan W; Dawson, Lisa F
Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage. (2015)
Peltier, Johann; Shaw, Helen A; Couchman, Edward C; Dawson, Lisa F; Yu, Lu; Choudhary, Jyoti S; Kaever, Volkhard; Wren, Brendan W; Fairweather, Neil F
Disparate subcellular location of putative sortase substrates in Clostridium difficile. (2017)
Peltier, Johann; Shaw, Helen A; Wren, Brendan W; Fairweather, Neil F
Inactivation of bpsl1039-1040 ATP-binding cassette transporter reduces intracellular survival in macrophages, biofilm formation and virulence in the murine model of Burkholderia pseudomallei infection. (2018)
Pinweha, Peechanika; Pumirat, Pornpan; Cuccui, Jon; Jitprasutwit, Niramol; Muangsombut, Veerachat; Srinon, Varintip; Boonyuen, Usa; Thiennimitr, Parameth; Vattanaviboon, Paiboon; Cia, Felipe; Willcocks, Sam; Bancroft, Gregory J; Wren, Brendan W; Korbsrisate, Sunee
In vitro and in vivo properties of the bovine antimicrobial peptide, Bactenecin 5. (2019)
Price, RL; Bugeon, L; Mostowy, S; Makendi, C; Wren, BW; Williams, HD; Willcocks, SJ
Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. (2010)
Pumirat, Pornpan; Cuccui, Jon; Stabler, Richard A; Stevens, Joanne M; Muangsombut, Veerachat; Singsuksawat, Ekapot; Stevens, Mark P; Wren, Brendan W; Korbsrisate, Sunee
A recombinant conjugated pneumococcal vaccine that protects against murine infections with a similar efficacy to Prevnar-13. (2018)
Reglinski, Mark; Ercoli, Giuseppe; Plumptre, Charlie; Kay, Emily; Petersen, Fernanda C; Paton, James C; Wren, Brendan W; Brown, Jeremy S
The S-layer protein of a Clostridium difficile SLCT-11 strain displays a complex glycan required for normal cell growth and morphology. (2018)
Richards, Emma; Bouché, Laura; Panico, Maria; Arbeloa, Ana; Vinogradov, Evgeny; Morris, Howard; Wren, Brendan; Logan, Susan M; Dell, Anne; Fairweather, Neil F
Draft Genome Sequence of Robinsoniella peoriensis 6600698, a Confounder of Clostridium difficile Diagnosis. (2016)
Roberts, Chrissy H; Shaw, Helen Alexandra; Ferguson, Natalie; Holland, Mark; Wren, Brendan W; Stabler, Richard A
Development of an automated platform for the optimal production of glycoconjugate vaccines expressed in Escherichia coli. (2021)
Samaras, Jasmin J; Mauri, Marta; Kay, Emily J; Wren, Brendan W; Micheletti, Martina
The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics. (2019)
Shaw, HA; Preston, MD; Vendrik, KEW; Cairns, MD; Browne, HP; Stabler, RA; Crobach, MJT; Corver, J; Pituch, H; Ingebretsen, A; Pirmohamed, M; Faulds-Pain, A; Valiente, E; Lawley, TD; Fairweather, NF; Kuijper, EJ; Wren, BW
Clostridium difficile clade 3 (RT023) have a modified cell surface and contain a large transposable island with novel cargo. (2019)
Shaw, Helen Alexandra; Khodadoost, Ladan; Preston, Mark D; Corver, Jeroen; Mullany, Peter; Wren, Brendan W
Draft Genome Sequence of the Enteropathogenic Bacterium Campylobacter jejuni Strain cj255. (2015)
Siddiqui, Fariha Masood; Ibrahim, Muhammad; Noureen, Nighat; Noreen, Zobia; Titball, Richard W; Champion, Olivia L; Wren, Brendan W; Studholme, David; Bokhari, Habib
Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching. (2010)
Snyder, Lori AS; Loman, Nicholas J; Linton, James D; Langdon, Rebecca R; Weinstock, George M; Wren, Brendan W; Pallen, Mark J
Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. (2008)
Stabler, Richard A; Dawson, Lisa F; Oyston, Petra CF; Titball, Richard W; Wade, Jim; Hinds, Jason; Witney, Adam A; Wren, Brendan W
Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations. (2012)
Stabler, Richard A; Dawson, Lisa F; Valiente, Esmeralda; Cairns, Michelle D; Martin, Melissa J; Donahue, Elizabeth H; Riley, Thomas V; Songer, J Glenn; Kuijper, Ed J; Dingle, Kate E; Wren, Brendan W
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. (2009)
Stabler, Richard A; He, Miao; Dawson, Lisa; Martin, Melissa; Valiente, Esmeralda; Corton, Craig; Lawley, Trevor D; Sebaihia, Mohammed; Quail, Michael A; Rose, Graham; Gerding, Dale N; Gibert, Maryse; Popoff, Michel R; Parkhill, Julian; Dougan, Gordon; Wren, Brendan W
Pseudaminic acid on Campylobacter jejuni flagella modulates dendritic cell IL-10 expression via Siglec-10 receptor: a novel flagellin-host interaction. (2014)
Stephenson, Holly N; Mills, Dominic C; Jones, Hannah; Milioris, Enea; Copland, Alastair; Dorrell, Nick; Wren, Brendan W; Crocker, Paul R; Escors, David; Bajaj-Elliott, Mona
Gene function hypotheses for the Campylobacter jejuni glycome generated by a logic-based approach. (2013)
Sternberg, Michael JE; Tamaddoni-Nezhad, Alireza; Lesk, Victor I; Kay, Emily; Hitchen, Paul G; Cootes, Adrian; van Alphen, Lieke B; Lamoureux, Marc P; Jarrell, Harold C; Rawlings, Christopher J; Soo, Evelyn C; Szymanski, Christine M; Dell, Anne; Wren, Brendan W; Muggleton, Stephen H
In vitro and in vivo characterisation of Listeria monocytogenes outbreak isolates. (2019)
Stratakos, Alexandros Ch; Ijaz, Umer Zeeshan; Ward, Patrick; Linton, Mark; Kelly, Carmel; Pinkerton, Laurette; Scates, Pam; McBride, Jane; Pet, Ioan; Criste, Adriana; Stef, Ducu; Couto, Jillian M; Sloan, William T; Dorrell, Nick; Wren, Brendan W; Stef, Lavinia; Gundogdu, Ozan; Corcionivoschi, Nicolae
Identification and characterisation of a novel adhesin Ifp in Yersinia pseudotuberculosis. (2011)
Strong, Philippa CR; Hinchliffe, Stewart J; Patrick, Hannah; Atkinson, Steve; Champion, Olivia L; Wren, Brendan W
Steps toward broad-spectrum therapeutics: discovering virulence-associated genes present in diverse human pathogens. (2009)
Stubben, Chris J; Duffield, Melanie L; Cooper, Ian A; Ford, Donna C; Gans, Jason D; Karlyshev, Andrey V; Lingard, Bryan; Oyston, Petra CF; de Rochefort, Anna; Song, Jian; Wren, Brendan W; Titball, Rick W; Wolinsky, Murray
PglB function and glycosylation efficiency is temperature dependent when the pgl locus is integrated in the Escherichia coli chromosome. (2022)
Terra, Vanessa S; Mauri, Marta; Sannasiddappa, Thippeswamy H; Smith, Alexander A; Stevens, Mark P; Grant, Andrew J; Wren, Brendan W; Cuccui, Jon; Glycoengineering of Veterinary Vaccines consortium (GoVV)
Construction of a pneumolysin deficient mutant in streptococcus pneumoniae serotype 1 strain 519/43 and phenotypic characterisation. (2020)
Terra, Vanessa S; Plumptre, Charles D; Wall, Emma C; Brown, Jeremy S; Wren, Brendan W
The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications. (2016)
Thi Khanh Nhu, Nguyen; Riordan, David W; Do Hoang Nhu, Tran; Thanh, Duy Pham; Thwaites, Guy; Huong Lan, Nguyen Phu; Wren, Brendan W; Baker, Stephen; Stabler, Richard A
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. (2006)
Thomson, Nicholas R; Howard, Sarah; Wren, Brendan W; Holden, Matthew TG; Crossman, Lisa; Challis, Gregory L; Churcher, Carol; Mungall, Karen; Brooks, Karen; Chillingworth, Tracey; Feltwell, Theresa; Abdellah, Zahra; Hauser, Heidi; Jagels, Kay; Maddison, Mark; Moule, Sharon; Sanders, Mandy; Whitehead, Sally; Quail, Michael A; Dougan, Gordon; Parkhill, Julian; Prentice, Michael B
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. (2006)
Thomson, Nicholas R; Howard, Sarah; Wren, Brendan W; Holden, Matthew TG; Crossman, Lisa; Challis, Gregory L; Churcher, Carol; Mungall, Karen; Brooks, Karen; Chillingworth, Tracey; Feltwell, Theresa; Abdellah, Zahra; Hauser, Heidi; Jagels, Kay; Maddison, Mark; Moule, Sharon; Sanders, Mandy; Whitehead, Sally; Quail, Michael A; Dougan, Gordon; Parkhill, Julian; Prentice, Michael B
Prevalence of Type VI Secretion System in Spanish Campylobacter jejuni Isolates. (2014)
Ugarte-Ruiz, M; Stabler, RA; Domínguez, L; Porrero, MC; Wren, BW; Dorrell, N; Gundogdu, O
Exploring the oxidative, antimicrobial and genomic properties of Campylobacter jejuni strains isolated from poultry. (2018)
Ugarte-Ruiz, Maria; Domínguez, Lucas; Corcionivoschi, Nicolae; Wren, Brendan W; Dorrell, Nick; Gundogdu, Ozan
Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation. (2016)
Valiente, Esmeralda; Bouché, Laura; Hitchen, Paul; Faulds-Pain, Alexandra; Songane, Mario; Dawson, Lisa F; Donahue, Elizabeth; Stabler, Richard A; Panico, Maria; Morris, Howard R; Bajaj-Elliott, Mona; Logan, Susan M; Dell, Anne; Wren, Brendan W
Vibrio cholerae accessory colonisation factor AcfC: a chemotactic protein with a role in hyperinfectivity. (2018)
Valiente, Esmeralda; Davies, Cadi; Mills, Dominic C; Getino, Maria; Ritchie, Jennifer M; Wren, Brendan W
Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage. (2011)
Valiente, Esmeralda; Dawson, Lisa F; Cairns, Michelle D; Stabler, Richard A; Wren, Brendan W
Evaluation of a Campylobacter jejuni N-glycan-ExoA glycoconjugate vaccine to reduce C. jejuni colonisation in chickens. (2021)
Vohra, Prerna; Chintoan-Uta, Cosmin; Bremner, Abi; Mauri, Marta; Terra, Vanessa S; Cuccui, Jon; Wren, Brendan W; Vervelde, Lonneke; Stevens, Mark P; Glycoengineering of Veterinary Vaccines Consortium
Evaluation of Glycosylated FlpA and SodB as Subunit Vaccines Against Campylobacter jejuni Colonisation in Chickens. (2020)
Vohra, Prerna; Chintoan-Uta, Cosmin; Terra, Vanessa S; Bremner, Abi; Cuccui, Jon; Wren, Brendan W; Vervelde, Lonneke; Stevens, Mark P
CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With Streptococcus pneumoniae Meningitis. (2020)
Wall, Emma C; Brownridge, Philip; Laing, Gavin; Terra, Vanessa S; Mlozowa, Veronica; Denis, Brigitte; Nyirenda, Mulinda; Allain, Theresa; Ramos-Sevillano, Elisa; Carrol, Enitan; Collins, Andrea; Gordon, Stephen B; Lalloo, David G; Wren, Brendan; Beynon, Robert; Heyderman, Robert S; Brown, Jeremy S
Erratum: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2015)
Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Chau, Nguyen Van Vinh; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium
Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2015)
Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Van Vinh Chau, Nguyen; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium
Publisher Correction: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2019)
Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Van Vinh Chau, Nguyen; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium
Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales. (2019)
Wileman, Thomas M; Weinert, Lucy A; Howell, Kate J; Wang, Jinhong; Peters, Sarah E; Williamson, Susanna M; Wells, Jerry M; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W
Revisiting aminocoumarins for the treatment of melioidosis. (2020)
Willcocks, SJ; Cia, F; Francisco, AF; Wren, BW
Intracellular replication of the well-armed pathogen Burkholderia pseudomallei. (2016)
Willcocks, Sam J; Denman, Carmen C; Atkins, Helen S; Wren, Brendan W
Virulence of the emerging pathogen, Burkholderia pseudomallei, depends upon the O-linked oligosaccharyltransferase, PglL. (2020)
Willcocks, Samuel J; Denman, Carmen; Cia, Felipe; McCarthy, Elizabeth; Cuccui, Jon; Wren, Brendan W
High-throughput analysis of Yersinia pseudotuberculosis gene essentiality in optimised in vitro conditions, and implications for the speciation of Yersinia pestis. (2018)
Willcocks, Samuel J; Stabler, Richard A; Atkins, Helen S; Oyston, Petra F; Wren, Brendan W
Genome-wide assessment of antimicrobial tolerance in Yersinia pseudotuberculosis under ciprofloxacin stress. (2019)
Willcocks, Samuel; Huse, Kristin K; Stabler, Richard; Oyston, Petra CF; Scott, Andrew; Atkins, Helen S; Wren, Brendan W
BμG@Sbase--a microbial gene expression and comparative genomic database. (2011)
Witney, Adam A; Waldron, Denise E; Brooks, Lucy A; Tyler, Richard H; Withers, Michael; Stoker, Neil G; Wren, Brendan W; Butcher, Philip D; Hinds, Jason
Microarrays for bacterial pathogens - hope or hype? (2002)
Wren, Brendan W
Structure-activity relationships in a new class of non-substrate-like covalent inhibitors of the bacterial glycosyltransferase LgtC. (2018)
Xu, Yong; Cuccui, Jon; Denman, Carmen; Maharjan, Tripty; Wren, Brendan W; Wagner, Gerd K
Type III secretion system confers enhanced virulence in clinical non-O1/non-O139 Vibrio cholerae. (2019)
Zeb, Samia; Shah, Muhammad Ali; Yasir, Muhammad; Awan, Hassaan Mehboob; Prommeenate, Peerada; Klanchui, Amornpan; Wren, Brendan W; Thomson, Nicholas; Bokhari, Habib
Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1. (2010)
Zelmer, Andrea; Martin, Melissa J; Gundogdu, Ozan; Birchenough, George; Lever, Rebecca; Wren, Brendan W; Luzio, J Paul; Taylor, Peter W
Biological roles of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. (2014)
van Alphen, Lieke B; Wenzel, Cory Q; Richards, Michele R; Fodor, Christopher; Ashmus, Roger A; Stahl, Martin; Karlyshev, Andrey V; Wren, Brendan W; Stintzi, Alain; Miller, William G; Lowary, Todd L; Szymanski, Christine M
New levels of sophistication in the transcriptional landscape of bacteria. (2009)
van Vliet, Arnoud Hm; Wren, Brendan W