Items where Author is "Douglas, I"

Year Item Type Full Text

Bibliographic data only

How Long Do Children Stay on Antiepileptic Treatments in the UK? (2011) Beau, R; Douglas, I; Evans, S; Clayton, T; Smeeth, L

Comparison of Retention Rates of First Line Antiepileptic Drugs in Children in the UK. (2011) Beau, R; Douglas, I; Stephen, E; Clayton, T; Smeeth, L

The Risk of Cancer Associated with Angiotensin-II Receptor Blockers. (2011) Bhaskaran, K; Douglas, I; Evans, S; van Staa, T; Smeeth, L

Using the Self Controlled Case Series Method To Assess the Risk of Myocardial Infarction in GPRD-Registered Users of Antipsychotic Agents. (2011) Brauer, R; Douglas, I; Smeeth, L

A Comparison between the Standard Self Controlled Case Series Design and a Modification To Account for Events That Censor the Observation Period. (2012) Brauer, R; Smeeth, L; Anaya-Izquierdo, K; Farrington, CP; Whitaker, H; Douglas, I

Risk of acute liver injury associated with use of antibiotics. Comparative cohort and nested case-control studies using two primary care databases in Europe. (2015) Brauer, Ruth; Douglas, Ian; Garcia Rodriguez, Luis Alberto; Downey, Gerald; Huerta, Consuelo; de Abajo, Francisco; Bate, Andrew; Feudjo Tepie, Maurille; de Groot, Mark CH; Schlienger, Raymond; Reynolds, Robert; Smeeth, Liam; Klungel, Olaf; Ruigómez, Ana

A Cohort Study Using GPRD and MINAP Data To Investigate the Possible Drug Interaction between Clopidogrel and Cytochrome P450 2C19 Inhibitors. (2011) Douglas, I; Smeeth, L; Hingorani, A; Grosso, A; Evans, S

A propensity score controlled cohort study to investigate the effects of statins. (2007) Douglas, IJ; Smeeth, L; Evans, SJ

A case-control study of drug risk factors for age-related macular degeneration. (2007) Douglas, Ian J; Cook, Claire; Chakravarthy, Usha; Hubbard, Richard; Fletcher, Astrid E; Smeeth, Liam

The use of antidepressants and the risk of haemorrhagic stroke: a nested case control study. (2011) Douglas, Ian; Smeeth, Liam; Irvine, David

Self-Controlled Case Series Analysis With Event-Dependent Observation Periods. (2011) Farrington, C Paddy; Anaya-Izquierdo, Karim; Whitaker, Heather J; Hocine, Mounia N; Douglas, Ian; Smeeth, Liam

Self-controlled case series with multiple event types. (2017) Ghebremichael-Weldeselassie, Yonas; Whitaker, Heather J; Douglas, Ian J; Smeeth, Liam; Farrington, C Paddy

Inhaled tiotropium bromide and risk of stroke. (2009) Grosso, Anthony; Douglas, Ian; Hingorani, Aroon D; MacAllister, Raymond; Hubbard, Richard; Smeeth, Liam

Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions. (2008) Grosso, Anthony; Douglas, Ian; Hingorani, Aroon; MacAllister, Raymond; Smeeth, Liam

Abstracts of the 27th International Conference on Pharmacoepidemiology & Therapeutic Risk Management. Chicago, Illinois, USA. August 14-17, 2011. (2011) Langham, Julia; Douglas, Ian; Brauer, Ruth; Bhaskaran, Krishnan; Smeeth, Liam

THE APPLICATION OF DISCRETE EVENT SIMULATION TO QUANTITATIVE RISK BENEFIT ANALYSIS. (2009) Maguire, A; Douglas, I; Blak, BT

Patterns of cholesterol levels in patients treated with lipid lowering drugs in UK primary care. (2007) Maguire, A; Douglas, I; Smeeth, L

Determinants of cholesterol and triglycerides recording in patients treated with lipid lowering therapy in UK primary care. (2007) Maguire, A; Douglas, I; Smeeth, L; Thompson, M

Classification of hyperlipidemia from automated primary care data in the UK and France. (2007) Maguire, A; Schwalm, MS; Douglas, I; Smeeth, L

Methylphenidate and the risk of trauma. (2014) Man, Kenneth KC; Chan, Esther W; Coghill, David; Douglas, Ian; Ip, Patrick; Leung, Ling-Pong; Tsui, Matthew SH; Wong, Wilfred HS; Wong, Ian CK

Herpes zoster, acute cardiovascular events and the role of zoster vaccination. (2015) Minassian, C; Thomas, S; Smeeth, L; Douglas, I; Brauer, R; Langan, S

Age-related macular degeneration and complement activation-related diseases: a population-based case-control study. (2008) Nitsch, Dorothea; Douglas, Ian; Smeeth, Liam; Fletcher, Astrid

BMI and risk of dementia in two million people over two decades: a retrospective cohort study. (2015) Qizilbash, Nawab; Gregson, John; Johnson, Michelle E; Pearce, Neil; Douglas, Ian; Wing, Kevin; Evans, Stephen JW; Pocock, Stuart J

The identification of incident cancers in UK primary care databases: a systematic review. (2014) Rañopa, Michael; Douglas, Ian; van Staa, Tjeerd; Smeeth, Liam; Klungel, Olaf; Reynolds, Robert; Bhaskaran, Krishnan

Re: Biomedical Informatics Approaches to Identifying Drug-Drug Interactions: Application to Insulin Secretagogues. (2017) Root, Adrian; Douglas, Ian; Evans, Stephen

OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS. (2016) Sinnott, SJ; Root, A; Mathur, R; Mansfield, K; Tomlinson, L; Douglas, I

OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS. (2016) Sinnott, SJ; Root, A; Mathur, R; Mansfield, K; Tomlinson, L; Douglas, I

Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials. (2009) Smeeth, Liam; Douglas, Ian; Hall, Andrew J; Hubbard, Richard; Evans, Stephen

Commentary: we still need observational studies of drugs--they just need to be better. (2006) Smeeth, Liam; Douglas, Ian; Hubbard, Richard

Risk of pancreatic cancer associated with use of incretin-based therapy and other glucose-lowering agents: a nationwide case-control study in Denmark. (2015) Thomsen, RW; Christensen, DH; Kahlert, J; Knudsen, ST; Pedersen, L; Norrelund, H; Dekkers, OM; Douglas, I; Marchesini, G; Smeeth, L; Moller, N; Beck-Nielsen, H; Jorgensen, JO; Sorensen, HT

Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0. (2017) Wang, Shirley V; Schneeweiss, Sebastian; Berger, Marc L; Brown, Jeffrey; de Vries, Frank; Douglas, Ian; Gagne, Joshua J; Gini, Rosa; Klungel, Olaf; Mullins, C Daniel; Nguyen, Michael D; Rassen, Jeremy A; Smeeth, Liam; Sturkenboom, Miriam; joint ISPE‐ISPOR Special Task Force on Real World Evidence in He

Public

Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence. (2016) Beau-Lejdstrom, Raphaelle; Douglas, Ian; Evans, Stephen JW; Smeeth, Liam

Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. (2021) Bhaskaran, Krishnan; Bacon, Sebastian; Evans, Stephen Jw; Bates, Chris J; Rentsch, Christopher T; MacKenna, Brian; Tomlinson, Laurie; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Grint, Daniel; Mehrkar, Amir; Eggo, Rosalind M; Inglesby, Peter; Douglas, Ian J; McDonald, Helen I; Cockburn, Jonathan; Williamson, Elizabeth J; Evans, David; Curtis, Helen J; Hulme, William J; Parry, John; Hester, Frank; Harper, Sam; Spiegelhalter, David; Smeeth, Liam; Goldacre, Ben

Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK. (2018) Bhaskaran, Krishnan; Dos-Santos-Silva, Isabel; Leon, David A; Douglas, Ian J; Smeeth, Liam

Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database. (2012) Bhaskaran, Krishnan; Douglas, Ian; Evans, Stephen; van Staa, Tjeerd; Smeeth, Liam

Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults. (2014) Bhaskaran, Krishnan; Douglas, Ian; Forbes, Harriet; dos-Santos-Silva, Isabel; Leon, David A; Smeeth, Liam

Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research Datalink (CPRD). (2013) Bhaskaran, Krishnan; Forbes, Harriet J; Douglas, Ian; Leon, David A; Smeeth, Liam

Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform. (2022) Bhaskaran, Krishnan; Rentsch, Christopher T; Hickman, George; Hulme, William J; Schultze, Anna; Curtis, Helen J; Wing, Kevin; Warren-Gash, Charlotte; Tomlinson, Laurie; Bates, Chris J; Mathur, Rohini; MacKenna, Brian; Mahalingasivam, Viyaasan; Wong, Angel; Walker, Alex J; Morton, Caroline E; Grint, Daniel; Mehrkar, Amir; Eggo, Rosalind M; Inglesby, Peter; Douglas, Ian J; McDonald, Helen I; Cockburn, Jonathan; Williamson, Elizabeth J; Evans, David; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Bacon, Sebastian; Smeeth, Liam; Goldacre, Ben

Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers: lessons for COVID-19 from a nationwide cohort study. (2020) Bidulka, Patrick; Iwagami, Masao; Mansfield, Kathryn E; Kalogirou, Fotini; Wong, Angel YS; Douglas, Ian J; Smeeth, Liam; Summers, Charlotte; Tomlinson, Laurie A

Protocol for an observational cohort study investigating personalised medicine for intensification of treatment in people with type 2 diabetes mellitus: the PERMIT study. (2021) Bidulka, Patrick; O'Neill, Stephen; Basu, Anirban; Wilkinson, Samantha; Silverwood, Richard J; Charlton, Paul; Briggs, Andrew; Adler, Amanda I; Khunti, Kamlesh; Tomlinson, Laurie A; Smeeth, Liam; Douglas, Ian J; Grieve, Richard

Cost saving of switching to equivalent inhalers and its effect on health outcomes. (2019) Bloom, Chloe I; Douglas, Ian; Olney, Jack; D'Ancona, Grainne; Smeeth, Liam; Quint, Jennifer K

Exacerbation risk and characterisation of the UK's asthma population from infants to old age. (2017) Bloom, Chloe I; Nissen, Francis; Douglas, Ian J; Smeeth, Liam; Cullinan, Paul; Quint, Jennifer K

Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study. (2015) Brauer, Ruth; Bhaskaran, Krishnan; Chaturvedi, Nishi; Dexter, David T; Smeeth, Liam; Douglas, Ian

The association between antipsychotic agents and the risk of myocardial infarction: a systematic review. (2011) Brauer, Ruth; Douglas, Ian; Smeeth, Liam

Prevalence of antibiotic use: a comparison across various European health care data sources. (2015) Brauer, Ruth; Ruigómez, Ana; Downey, Gerry; Bate, Andrew; Garcia Rodriguez, Luis Alberto; Huerta, Consuelo; Gil, Miguel; de Abajo, Francisco; Requena, Gema; Alvarez, Yolanda; Slattery, Jim; de Groot, Mark; Souverein, Patrick; Hesse, Ulrik; Rottenkolber, Marietta; Schmiedl, Sven; de Vries, Frank; Tepie, Maurille Feudjo; Schlienger, Raymond; Smeeth, Liam; Douglas, Ian; Reynolds, Robert; Klungel, Olaf

The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies. (2015) Brauer, Ruth; Ruigómez, Ana; Klungel, Olaf; Reynolds, Robert; Feudjo Tepie, Maurille; Smeeth, Liam; Douglas, Ian

Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study. (2014) Brauer, Ruth; Smeeth, Liam; Anaya-Izquierdo, Karim; Timmis, Adam; Denaxas, Spiros C; Farrington, C Paddy; Whitaker, Heather; Hemingway, Harry; Douglas, Ian

Proton pump inhibitors and risk of all-cause and cause-specific mortality: A cohort study. (2021) Brown, Jeremy P; Tazare, John R; Williamson, Elizabeth; Mansfield, Kathryn E; Evans, Stephen J; Tomlinson, Laurie A; Bhaskaran, Krishnan; Smeeth, Liam; Wing, Kevin; Douglas, Ian J

Use of real-world evidence in postmarketing medicines regulation in the European Union: a systematic assessment of European Medicines Agency referrals 2013-2017. (2019) Brown, Jeremy Philip; Wing, Kevin; Evans, Stephen J; Bhaskaran, Krishnan; Smeeth, Liam; Douglas, Ian J

Association between oral fluoroquinolones and seizures: A self-controlled case series study. (2016) Chui, Celine SL; Chan, Esther W; Wong, Angel YS; Root, Adrian; Douglas, Ian J; Wong, Ian CK ['material/summary:fileicon_application/msword' not defined]

Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study. (2018) Crellin, Elizabeth; Mansfield, Kathryn E; Leyrat, Clémence; Nitsch, Dorothea; Douglas, Ian J; Root, Adrian; Williamson, Elizabeth; Smeeth, Liam; Tomlinson, Laurie A

Recording of 'COVID-19 vaccine declined': a cohort study on 57.9 million National Health Service patients' records in situ using OpenSAFELY, England, 8 December 2020 to 25 May 2021. (2022) Curtis, Helen J; Inglesby, Peter; MacKenna, Brian; Croker, Richard; Hulme, William J; Rentsch, Christopher T; Bhaskaran, Krishnan; Mathur, Rohini; Morton, Caroline E; Bacon, Sebastian Cj; Smith, Rebecca M; Evans, David; Mehrkar, Amir; Tomlinson, Laurie; Walker, Alex J; Bates, Christopher; Hickman, George; Ward, Tom; Morley, Jessica; Cockburn, Jonathan; Davy, Simon; Williamson, Elizabeth J; Eggo, Rosalind M; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben

Trends and clinical characteristics of COVID-19 vaccine recipients: a federated analysis of 57.9 million patients’ primary care records in situ using OpenSAFELY. (2021) Curtis, Helen J; Inglesby, Peter; Morton, Caroline E; MacKenna, Brian; Green, Amelia; Hulme, William; Walker, Alex J; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth J; Rowan, Anna; Fisher, Louis; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J; Evans, Stephen Jw; Smeeth, Liam; Goldacre, Ben; (The OpenSAFELY Collaborative)

OpenSAFELY NHS Service Restoration Observatory 1: primary care clinical activity in England during the first wave of COVID-19. (2021) Curtis, Helen J; MacKenna, Brian; Croker, Richard; Inglesby, Peter; Walker, Alex J; Morley, Jessica; Mehrkar, Amir; Morton, Caroline E; Bacon, Seb; Hickman, George; Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth J; Hulme, William J; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben; (The OpenSAFELY Collaborative)

OpenSAFELY: impact of national guidance on switching from warfarin to direct oral anticoagulants (DOACs) in early phase of COVID-19 pandemic in England. (2020) Curtis, Helen J; MacKenna, Brian; Walker, Alex J; Croker, Richard; Mehrkar, Amir; Morton, Caroline E; Bacon, Seb; Hickman, George; Inglesby, Peter; Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth; Hulme, William; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben

Approaches for combining primary care electronic health record data from multiple sources: a systematic review of observational studies. (2020) Dedman, Daniel; Cabecinha, Melissa; Williams, Rachael; Evans, Stephen JW; Bhaskaran, Krishnan; Douglas, Ian J

Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care. (2015) Douglas, Ian J; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam

The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort. (2015) Douglas, Ian J; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam

The risk of fractures associated with thiazolidinediones: a self-controlled case-series study. (2009) Douglas, Ian J; Evans, Stephen J; Pocock, Stuart; Smeeth, Liam

Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs. (2012) Douglas, Ian J; Evans, Stephen JW; Hingorani, Aroon D; Grosso, Anthony M; Timmis, Adam; Hemingway, Harry; Smeeth, Liam

Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink. (2013) Douglas, Ian J; Langham, Julia; Bhaskaran, Krishnan; Brauer, Ruth; Smeeth, Liam

Oral Fluoroquinolone Use and Retinal Detachment. (2016) Douglas, Ian J; Root, Adrian; Krishnan, Bhaskaran

Exposure to antipsychotics and risk of stroke: self controlled case series study. (2008) Douglas, Ian J; Smeeth, Liam

Juvenile Huntington's disease: a population-based study using the General Practice Research Database. (2013) Douglas, Ian; Evans, Stephen; Rawlins, Michael D; Smeeth, Liam; Tabrizi, Sarah J; Wexler, Nancy S

Effect of statin treatment on short term mortality after pneumonia episode: cohort study. (2011) Douglas, Ian; Evans, Stephen; Smeeth, Liam

Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records. (2013) Evans, Stephen JW; Douglas, Ian; Rawlins, Michael D; Wexler, Nancy S; Tabrizi, Sarah J; Smeeth, Liam

Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data. (2020) Forbes, Harriet; Douglas, Ian; Finn, Adam; Breuer, Judith; Bhaskaran, Krishnan; Smeeth, Liam; Packer, Simon; Langan, Sinéad M; Mansfield, Kathryn E; Marlow, Robin; Whitaker, Heather; Warren-Gash, Charlotte

Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England. (2021) Forbes, Harriet; Morton, Caroline E; Bacon, Seb; McDonald, Helen I; Minassian, Caroline; Brown, Jeremy P; Rentsch, Christopher T; Mathur, Rohini; Schultze, Anna; DeVito, Nicholas J; MacKenna, Brian; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Drysdale, Henry; Wong, Angel YS; Cockburn, Jonathan; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Evans, Stephen JW; Bhaskaran, Krishnan; Eggo, Rosalind M; Goldacre, Ben; Tomlinson, Laurie A

Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England. (2020) Forbes, Harriet; Morton, Caroline E; Bacon, Seb; McDonald, Helen I; Minassian, Caroline; Brown, Jeremy P; Rentsch, Christopher T; Mathur, Rohini; Schultze, Anna; DeVito, Nicholas J; MacKenna, Brian; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Drysdale, Henry; Wong, Angel YS; Cockburn, Jonathan; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Evans, Stephen JW; Bhaskaran, Krishnan; Eggo, Rosalind M; Goldacre, Ben; Tomlinson, Laurie A

Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink. (2014) Goh, Kah L; Bhaskaran, Krishnan; Minassian, Caroline; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J

Blood pressure and risk of dementia and its subtypes: a historical cohort study with long-term follow-up in 2.6 million people. (2019) Gregson, J; Qizilbash, N; Iwagami, M; Douglas, I; Johnson, M; Pearce, N; Pocock, S description

Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England. (2021) Grint, Daniel J; Wing, Kevin; Houlihan, Catherine; Gibbs, Hamish P; Evans, Stephen JW; Williamson, Elizabeth; McDonald, Helen I; Bhaskaran, Krishnan; Evans, David; Walker, Alex J; Hickman, George; Nightingale, Emily; Schultze, Anna; Rentsch, Christopher T; Bates, Chris; Cockburn, Jonathan; Curtis, Helen J; Morton, Caroline E; Bacon, Sebastian; Davy, Simon; Wong, Angel YS; Mehrkar, Amir; Tomlinson, Laurie; Douglas, Ian J; Mathur, Rohini; MacKenna, Brian; Ingelsby, Peter; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; DeVito, Nicholas J; Hulme, Will; Tazare, John; Smeeth, Liam; Goldacre, Ben; Eggo, Rosalind M

Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February. (2021) Grint, Daniel J; Wing, Kevin; Williamson, Elizabeth; McDonald, Helen I; Bhaskaran, Krishnan; Evans, David; Evans, Stephen Jw; Walker, Alex J; Hickman, George; Nightingale, Emily; Schultze, Anna; Rentsch, Christopher T; Bates, Chris; Cockburn, Jonathan; Curtis, Helen J; Morton, Caroline E; Bacon, Sebastian; Davy, Simon; Wong, Angel Ys; Mehrkar, Amir; Tomlinson, Laurie; Douglas, Ian J; Mathur, Rohini; Blomquist, Paula; MacKenna, Brian; Ingelsby, Peter; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; DeVito, Nicholas J; Hulme, Will; Tazare, John; Goldacre, Ben; Smeeth, Liam; Eggo, Rosalind M

Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis. (2009) Grosso, Anthony; Douglas, Ian; Hingorani, Aroon; MacAllister, Raymond; Smeeth, Liam

Use of the self-controlled case series method in drug safety assessment. (2011) Grosso, Anthony; Douglas, Ian; MacAllister, Raymond; Petersen, Irene; Smeeth, Liam; Hingorani, Aroon D

The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom. (2015) Hayes, JF; Bhaskaran, K; Batterham, R; Smeeth, L; Douglas, I description

Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY. (2022) Hulme, William J; Williamson, Elizabeth J; Green, Amelia CA; Bhaskaran, Krishnan; McDonald, Helen I; Rentsch, Christopher T; Schultze, Anna; Tazare, John; Curtis, Helen J; Walker, Alex J; Tomlinson, Laurie A; Palmer, Tom; Horne, Elsie MF; MacKenna, Brian; Morton, Caroline E; Mehrkar, Amir; Morley, Jessica; Fisher, Louis; Bacon, Sebastian CJ; Evans, David; Inglesby, Peter; Hickman, George; Davy, Simon; Ward, Tom; Croker, Richard; Eggo, Rosalind M; Wong, Angel YS; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Grint, Daniel J; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Sterne, Jonathan AC; Hernán, Miguel A; Goldacre, Ben

Blood cholesterol and risk of dementia in more than 1·8 million people over two decades: a retrospective cohort study. (2021) Iwagami, Masao; Qizilbash, Nawab; Gregson, John; Douglas, Ian; Johnson, Michelle; Pearce, Neil; Evans, Stephen; Pocock, Stuart

Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study. (2018) Iwagami, Masao; Tomlinson, Laurie A; Mansfield, Kathryn E; Douglas, Ian J; Smeeth, Liam; Nitsch, Dorothea

Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink. (2018) Koppe, Uwe; Nitsch, Dorothea; Mansfield, Kathryn E; Mathur, Rohini; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam; Douglas, Ian J

Thromboembolic, bleeding, and mortality risks among patients with nonvalvular atrial fibrillation treated with dual antiplatelet therapy versus oral anticoagulants: A population-based study. (2019) Lau, Wallis CY; Douglas, Ian J; Wong, Ian CK; Smeeth, Liam; Lip, Gregory YH; Leung, Wai K; Siu, Chung-Wah; Cheung, Bernard MY; Mok, Michael TC; Chan, Esther W

Propensity score analysis with partially observed covariates: How should multiple imputation be used? (2017) Leyrat, C; Seaman, SR; White, IR; Douglas, I; Smeeth, L; Kim, J; Resche-Rigon, M; Carpenter, JR; Williamson, EJ

Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform. (2022) MacKenna, Brian; Kennedy, Nicholas A; Mehrkar, Amir; Rowan, Anna; Galloway, James; Matthewman, Julian; Mansfield, Kathryn E; Bechman, Katie; Yates, Mark; Brown, Jeremy; Schultze, Anna; Norton, Sam; Walker, Alex J; Morton, Caroline E; Harrison, David; Bhaskaran, Krishnan; Rentsch, Christopher T; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hickman, George; Ward, Tom; Davy, Simon; Green, Amelia; Fisher, Louis; Hulme, William; Bates, Chris; Curtis, Helen J; Tazare, John; Eggo, Rosalind M; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie A; Mathur, Rohini; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Lees, Charlie W; Evans, Stephen JW; Goldacre, Ben; Smith, Catherine H; Langan, Sinéad M

Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink. (2014) Macedo, Ana Filipa; Douglas, Ian; Smeeth, Liam; Forbes, Harriet; Ebrahim, Shah

Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis. (2018) Mansfield, Kathryn E; Douglas, Ian J; Nitsch, Dorothea; Thomas, Sara L; Smeeth, Liam; Tomlinson, Laurie A

Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014. (2017) Mathur, Rohini; Bhaskaran, Krishnan; Edwards, Emma; Lee, Helen; Chaturvedi, Nishi; Smeeth, Liam; Douglas, Ian

Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990-2017: A cohort study. (2020) Mathur, Rohini; Farmer, Ruth E; Eastwood, Sophie V; Chaturvedi, Nish; Douglas, Ian; Smeeth, Liam

Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform. (2020) Mathur, Rohini; Rentsch, Christopher T; Morton, Caroline E; Hulme, William J; Schultze, Anna; MacKenna, Brian; Eggo, Rosalind M; Bhaskaran, Krishnan; Wong, Angel YS; Williamson, Elizabeth J; Forbes, Harriet; Wing, Kevin; McDonald, Helen I; Bates, Chris; Bacon, Seb; Walker, Alex J; Evans, David; Inglesby, Peter; Mehrkar, Amir; Curtis, Helen J; DeVito, Nicholas J; Croker, Richard; Drysdale, Henry; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Tomlinson, Laurie; Evans, Stephen JW; Grieve, Richard; Harrison, David; Rowan, Kathy; Khunti, Kamlesh; Chaturvedi, Nishi; Smeeth, Liam; Goldacre, Ben; OpenSAFELY Collaborative

Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform. (2021) Mathur, Rohini; Rentsch, Christopher T; Morton, Caroline E; Hulme, William J; Schultze, Anna; MacKenna, Brian; Eggo, Rosalind M; Bhaskaran, Krishnan; Wong, Angel YS; Williamson, Elizabeth J; Forbes, Harriet; Wing, Kevin; McDonald, Helen I; Bates, Chris; Bacon, Seb; Walker, Alex J; Evans, David; Inglesby, Peter; Mehrkar, Amir; Curtis, Helen J; DeVito, Nicholas J; Croker, Richard; Drysdale, Henry; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Tomlinson, Laurie; Evans, Stephen JW; Grieve, Richard; Harrison, David; Rowan, Kathy; Khunti, Kamlesh; Chaturvedi, Nishi; Smeeth, Liam; Goldacre, Ben

Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink. (2016) Matthews, Anthony; Langan, Sinéad M; Douglas, Ian J; Smeeth, Liam; Bhaskaran, Krishnan

Cutting feedback in Bayesian regression adjustment for the propensity score. (2011) McCandless, Lawrence C; Douglas, Ian J; Evans, Stephen J; Smeeth, Liam

Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States. (2015) Minassian, Caroline; Thomas, Sara L; Smeeth, Liam; Douglas, Ian; Brauer, Ruth; Langan, Sinéad M

Cardiovascular Outcomes after a Respiratory Tract Infection among Adults with Non-Cystic Fibrosis Bronchiectasis: A General Population-based Study. (2017) Navaratnam, Vidya; Root, Adrian A; Douglas, Ian; Smeeth, Liam; Hubbard, Richard B; Quint, Jennifer K

Asthma in electronic health records: validity and phenotyping. (2019) Nissen, FW

Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink). (2019) Nissen, Francis; Douglas, Ian J; Müllerová, Hana; Pearce, Neil; Bloom, Chloe I; Smeeth, Liam; Quint, Jennifer K

Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care. (2018) Nissen, Francis; Morales, Daniel R; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; Quint, Jennifer K

Validation of asthma recording in the Clinical Practice Research Datalink (CPRD). (2017) Nissen, Francis; Morales, Daniel R; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; Quint, Jennifer K

How to validate a diagnosis recorded in electronic health records. (2019) Nissen, Francis; Quint, Jennifer K; Morales, Daniel R; Douglas, Ian J

Validation of asthma recording in electronic health records: a systematic review. (2017) Nissen, Francis; Quint, Jennifer K; Wilkinson, Samantha; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J

Validation of asthma recording in electronic health records: protocol for a systematic review. (2017) Nissen, Francis; Quint, Jennifer K; Wilkinson, Samantha; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J

OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic. (2021) OpenSAFELY Collaborative; Curtis, Helen J; MacKenna, Brian; Walker, Alex J; Croker, Richard; Mehrkar, Amir; Morton, Caroline; Bacon, Seb; Hickman, George; Inglesby, Peter; Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth; Hulme, William; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wong, Angel Yun; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian; Smeeth, Liam; Goldacre, Ben

Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY. (2022) OpenSAFELY Collaborative; Green, Amelia; Curtis, Helen; Hulme, William; Williamson, Elizabeth; McDonald, Helen; Bhaskaran, Krishnan; Rentsch, Christopher; Schultze, Anna; MacKenna, Brian; Mahalingasivam, Viyaasan; Tomlinson, Laurie; Walker, Alex; Fisher, Louis; Massey, Jon; Andrews, Colm; Hopcroft, Lisa; Morton, Caroline; Croker, Richard; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Evans, David; Inglesby, Peter; Hickman, George; Ward, Tom; Davy, Simon; Mathur, Rohini; Tazare, John; Eggo, Rosalind; Wing, Kevin; Wong, Angel; Forbes, Harriet; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian; Evans, Stephen; Smeeth, Liam; Goldacre, Ben

Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study. (2021) OpenSAFELY Collaborative; Wong, Angel YS; Tomlinson, Laurie A; Brown, Jeremy P; Elson, William; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Evans, David; Inglesby, Peter; MacKenna, Brian; Bhaskaran, Krishnan; Rentsch, Christopher T; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen I; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J

Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study. (2014) Perel, Pablo; Clayton, Tim; Altman, Doug G; Croft, Peter; Douglas, Ian; Hemingway, Harry; Hingorani, Aroon; Morley, Katherine I; Riley, Richard; Timmis, Adam; Van der Windt, Danielle; Roberts, Ian; PROGRESS Partnership

Self controlled case series methods: an alternative to standard epidemiological study designs. (2016) Petersen, Irene; Douglas, Ian; Whitaker, Heather

Real-world effects of medications for stroke prevention in atrial fibrillation: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results. (2021) Powell, Emma Maud; Douglas, Ian J; Gungabissoon, Usha; Smeeth, Liam; Wing, Kevin

Unicompartmental compared with total knee replacement for patients with multimorbidities: a cohort study using propensity score stratification and inverse probability weighting. (2021) Prats-Uribe, Albert; Kolovos, Spyros; Berencsi, Klara; Carr, Andrew; Judge, Andrew; Silman, Alan; Arden, Nigel; Petersen, Irene; Douglas, Ian J; Wilkinson, J Mark; Murray, David; Valderas, Jose M; Beard, David J; Lamb, Sarah E; Ali, M Sanni; Pinedo-Villanueva, Rafael; Strauss, Victoria Y; Prieto-Alhambra, Daniel

The Prevalence of Huntington's Disease. (2016) Rawlins, Michael D; Wexler, Nancy S; Wexler, Alice R; Tabrizi, Sarah J; Douglas, Ian; Evans, Stephen JW; Smeeth, Liam description

Methodological issues in electronic healthcare database studies of drug cancer associations: identification of cancer, and drivers of discrepant results. (2016) Rañopa, ME

Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study. (2021) Rentsch, Christopher T; Beckman, Joshua A; Tomlinson, Laurie; Gellad, Walid F; Alcorn, Charles; Kidwai-Khan, Farah; Skanderson, Melissa; Brittain, Evan; King, Joseph T; Ho, Yuk-Lam; Eden, Svetlana; Kundu, Suman; Lann, Michael F; Greevy, Robert A; Ho, P Michael; Heidenreich, Paul A; Jacobson, Daniel A; Douglas, Ian J; Tate, Janet P; Evans, Stephen JW; Atkins, David; Justice, Amy C; Freiberg, Matthew S

Early initiation of prophylactic anticoagulation for prevention of COVID-19 mortality: a nationwide cohort study of hospitalized patients in the United States. (2020) Rentsch, Christopher T; Beckman, Joshua A; Tomlinson, Laurie; Gellad, Walid F; Alcorn, Charles; Kidwai-Khan, Farah; Skanderson, Melissa; Brittain, Evan; King, Joseph T; Ho, Yuk-Lam; Eden, Svetlana; Kundu, Suman; Lann, Michael F; Greevy, Robert A; Ho, P Michael; Heidenreich, Paul A; Jacobson, Daniel A; Douglas, Ian J; Tate, Janet P; Evans, Stephen Jw; Atkins, David; Justice, Amy C; Freiberg, Matthew S

Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platform. (2020) Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben

Hydroxychloroquine treatment does not reduce COVID-19 mortality; underdosing to the wrong patients? - Authors' reply. (2021) Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben description

Hydroxychloroquine for prevention of COVID-19 mortality: a population-based cohort study. (2020) Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; J Hulme, William; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben

Impact of pre-exposure time bias in self-controlled case series when the event conditions the exposure: Hip/femur fracture and use of benzodiazepines as a case study. (2020) Requena, Gema; Douglas, Ian J; Huerta, Consuelo; de Abajo, Francisco

Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines. (2015) Requena, Gema; Logie, John; Martin, Elisa; Boudiaf, Nada; González González, Rocío; Huerta, Consuelo; Alvarez, Arturo; Webb, David; Bate, Andrew; García Rodríguez, Luis A; Reynolds, Robert; Schlienger, Raymond; Gardarsdottir, Helga; de Groot, Mark; Klungel, Olaf H; de Abajo, Fancisco; Douglas, Ian J

Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs. (2016) Root, AA; Wong, AY; Ghebremichael-Weldeselassie, Y; Smeeth, L; Bhaskaran, K; Evans, SJ; Brauer, R; Wong, IC; Navaratnam, V; Douglas, I

Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression. (2019) Root, Adrian; Brown, Jeremy P; Forbes, Harriet J; Bhaskaran, Krishnan; Hayes, Joseph; Smeeth, Liam; Douglas, Ian J

Myocardial Infarction and Ischemic Stroke after Exacerbations of Chronic Obstructive Pulmonary Disease. (2018) Rothnie, Kieran J; Connell, Olivia; Müllerová, Hana; Smeeth, Liam; Pearce, Neil; Douglas, Ian; Quint, Jennifer K

Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65. (2022) Schultze, Anna; Nightingale, Emily; Evans, David; Hulme, William; Rosello, Alicia; Bates, Chris; Cockburn, Jonathan; MacKenna, Brian; Curtis, Helen J; Morton, Caroline E; Croker, Richard; Bacon, Seb; McDonald, Helen I; Rentsch, Christopher T; Bhaskaran, Krishnan; Mathur, Rohini; Tomlinson, Laurie A; Williamson, Elizabeth J; Forbes, Harriet; Tazare, John; Grint, Daniel; Walker, Alex J; Inglesby, Peter; DeVito, Nicholas J; Mehrkar, Amir; Hickman, George; Davy, Simon; Ward, Tom; Fisher, Louis; Green, Amelia Ca; Wing, Kevin; Wong, Angel Ys; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Eggo, Rosalind M; Goldacre, Ben; Leon, David A

Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform. (2020) Schultze, Anna; Walker, Alex J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Quint, Jennifer; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; OpenSAFELY Collaborative

Inhaled corticosteroid use and risk COVID-19 related death among 966,461 patients with COPD or asthma: an OpenSAFELY analysis. (2020) Schultze, Anna; Walker, Alex J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Quint, Jennifer; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben

Comparative effectiveness of fourth-line anti-hypertensive agents in resistant hypertension: A systematic review and meta-analysis. (2016) Sinnott, SJ; Tomlinson, LA; Root, AA; Mathur, R; Mansfield, KE; Smeeth, L; Douglas, IJ

First line drug treatment for hypertension and reductions in blood pressure according to age and ethnicity: cohort study in UK primary care. (2020) Sinnott, Sarah-Jo; Douglas, Ian J; Smeeth, Liam; Williamson, Elizabeth; Tomlinson, Laurie A

Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015. (2017) Sinnott, Sarah-Jo; Smeeth, Liam; Williamson, Elizabeth; Douglas, Ian J

The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data. (2019) Sinnott, Sarah-Jo; Smeeth, Liam; Williamson, Elizabeth; Perel, Pablo; Nitsch, Dorothea; Tomlinson, Laurie A; Douglas, Ian J

The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database. (2013) Skow, Aine; Douglas, Ian; Smeeth, Liam

High-dimensional propensity scores for data-driven confounder adjustment in UK electronic health records. (2022) Tazare, JR

Implementing high-dimensional propensity score principles to improve confounder adjustment in UK electronic health records. (2020) Tazare, John; Smeeth, Liam; Evans, Stephen JW; Williamson, Elizabeth; Douglas, Ian J

Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19: a descriptive cohort study within the OpenSAFELY platform. (2021) Tazare, John; Walker, Alex J; Tomlinson, Laurie; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; Mathur, Rohini; Wong, Angel YS; Schultze, Anna; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; Davy, Simon; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Warren-Gash, Charlotte; Bhate, Ketaki; Nitsch, Dorothea; Powell, Emma; Mulick, Amy; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben

Transparency of high-dimensional propensity score analyses: Guidance for diagnostics and reporting. (2020) Tazare, John; Wyss, Richard; Franklin, Jessica M; Smeeth, Liam; Evans, Stephen JW; Wang, Shirley V; Schneeweiss, Sebastian; Douglas, Ian J; Williamson, Elizabeth; Gagne, Joshua J

Pharmacoepidemiology for nephrologists: do proton pump inhibitors cause chronic kidney disease? (2017) Tomlinson, Laurie A; Fogarty, Damian G; Douglas, Ian; Nitsch, Dorothea

Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient records in situ using OpenSAFELY. (2021) Walker, Alex J; MacKenna, Brian; Inglesby, Peter; Tomlinson, Laurie; Rentsch, Christopher T; Curtis, Helen J; Morton, Caroline E; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Williamson, Elizabeth J; Hulme, William J; McDonald, Helen I; Mathur, Rohini; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Tazare, John; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J; Evans, Stephen Jw; (The OpenSAFELY Collaborative)

Changes in the rate of cardiometabolic and pulmonary events during the COVID-19 pandemic. (2021) Walker, Alex J; Tazare, John; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; Mathur, Rohini; Wong, Angel YS; Schultze, Anna; Bacon, Sebastian CJ; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Tomlinson, Laurie; Goldacre, Ben

UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records. (2020) Walker, Jemma L; Grint, Daniel J; Strongman, Helen; Eggo, Rosalind M; Peppa, Maria; Minassian, Caroline; Mansfield, Kathryn E; Rentsch, Christopher T; Douglas, Ian J; Mathur, Rohini; Wong, Angel YS; Quint, Jennifer K; Andrews, Nick; Bernal, Jamie Lopez; Scott, J Anthony; Ramsay, Mary; Smeeth, Liam; McDonald, Helen

UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records. (2021) Walker, Jemma L; Grint, Daniel J; Strongman, Helen; Eggo, Rosalind M; Peppa, Maria; Minassian, Caroline; Mansfield, Kathryn E; Rentsch, Christopher T; Douglas, Ian J; Mathur, Rohini; Wong, Angel YS; Quint, Jennifer K; Andrews, Nick; Bernal, Jamie Lopez; Scott, J Anthony; Ramsay, Mary; Smeeth, Liam; McDonald, Helen I

Safety of COVID-19 vaccination and acute neurological events: A self-controlled case series in England using the OpenSAFELY platform. (2022) Walker, Jemma L; Schultze, Anna; Tazare, John; Tamborska, Arina; Singh, Bhagteshwar; Donegan, Katherine; Stowe, Julia; Morton, Caroline E; Hulme, William J; Curtis, Helen J; Williamson, Elizabeth J; Mehrkar, Amir; Eggo, Rosalind M; Rentsch, Christopher T; Mathur, Rohini; Bacon, Sebastian; Walker, Alex J; Davy, Simon; Evans, David; Inglesby, Peter; Hickman, George; MacKenna, Brian; Tomlinson, Laurie; Ca Green, Amelia; Fisher, Louis; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Bates, Christopher; Evans, Stephen Jw; Solomon, Tom; Andrews, Nick J; Douglas, Ian J; Goldacre, Ben; Smeeth, Liam; McDonald, Helen I

Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0. (2017) Wang, Shirley V; Schneeweiss, Sebastian; Berger, Marc L; Brown, Jeffrey; de Vries, Frank; Douglas, Ian; Gagne, Joshua J; Gini, Rosa; Klungel, Olaf; Mullins, C Daniel; Nguyen, Michael D; Rassen, Jeremy A; Smeeth, Liam; Sturkenboom, Miriam; joint ISPE-ISPOR Special Task Force on Real World Evidence in He

Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review. (2016) Wexler, Nancy S; Collett, Laura; Wexler, Alice R; Rawlins, Michael D; Tabrizi, Sarah J; Douglas, Ian; Smeeth, Liam; Evans, Stephen J

Investigating the assumptions of the self-controlled case series method. (2017) Whitaker, Heather J; Ghebremichael-Weldeselassie, Yonas; Douglas, Ian J; Smeeth, Liam; Farrington, C Paddy

A systematic review comparing the evidence for kidney function outcomes between oral antidiabetic drugs for type 2 diabetes. (2018) Wilkinson, Samantha V; Tomlinson, Laurie A; Iwagami, Masao; Stirnadel-Farrant, Heide A; Smeeth, Liam; Douglas, Ian

Factors associated with choice of intensification treatment for type 2 diabetes after metformin monotherapy: a cohort study in UK primary care. (2018) Wilkinson, Samantha; Douglas, Ian J; Williamson, Elizabeth; Stirnadel-Farrant, Heide A; Fogarty, Damian; Pokrajac, Ana; Smeeth, Liam; Tomlinson, Laurie A

Changing use of antidiabetic drugs in the UK: trends in prescribing 2000-2017. (2018) Wilkinson, Samantha; Douglas, Ian; Stirnadel-Farrant, Heide; Fogarty, Damian; Pokrajac, Ana; Smeeth, Liam; Tomlinson, Laurie

Comparative effects of sulphonylureas, dipeptidyl peptidase-4 inhibitors and sodium-glucose co-transporter-2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care. (2020) Wilkinson, Samantha; Williamson, Elizabeth; Pokrajac, Ana; Fogarty, Damian; Stirnadel-Farrant, Heide; Smeeth, Liam; Douglas, Ian J; Tomlinson, Laurie A

Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform. (2021) Williamson, Elizabeth J; McDonald, Helen I; Bhaskaran, Krishnan; Walker, Alex J; Bacon, Sebastian; Davy, Simon; Schultze, Anna; Tomlinson, Laurie; Bates, Chris; Ramsay, Mary; Curtis, Helen J; Forbes, Harriet; Wing, Kevin; Minassian, Caroline; Tazare, John; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Eggo, Rosalind M; Hulme, William; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Kuper, Hannah

OpenSAFELY: Risks of COVID-19 hospital admission and death for people with learning disabilities - a cohort study. (2021) Williamson, Elizabeth J; McDonald, Helen I; Bhaskaran, Krishnan; Walker, Alex J; Bacon, Sebastian; Davy, Simon; Schultze, Anna; Tomlinson, Laurie; Bates, Chris; Ramsay, Mary; Curtis, Helen J; Forbes, Harriet; Wing, Kevin; Minassian, Caroline; Tazare, John; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Eggo, Rosalind M; Hulme, Will; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Kuper, Hannah

Predicting COVID-19 related death using the OpenSAFELY platform. (2021) Williamson, Elizabeth J; Tazare, John; Bhaskaran, Krishnan; McDonald, Helen I; Walker, Alex J; Tomlinson, Laurie; Wing, Kevin; Bacon, Sebastian; Bates, Chris; Curtis, Helen J; Forbes, Harriet; Minassian, Caroline; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Nicholson, Brian D; Leon, Dave; Inglesby, Peter; MacKenna, Brian; Davies, Nicholas G; DeVito, Nicholas J; Drysdale, Henry; Cockburn, Jonathan; Hulme, Will; Morley, Jess; Douglas, Ian; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Grieve, Richard; Harrison, David A; Steyerberg, Ewout W; Eggo, Rosalind M; Diaz-Ordaz, Karla; Keogh, Ruth; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben

Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform. (2020) Williamson, Elizabeth J; Tazare, John; Bhaskaran, Krishnan; Walker, Alex J; McDonald, Helen I; Tomlinson, Laurie; Bacon, Sebastian; Bates, Chris; Curtis, Helen J; Forbes, Harriet; Minassian, Caroline; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Nicholson, Brian D; Leon, David; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Davies, Nicholas G; Hulme, William; Morley, Jessica; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Rafael; Grieve, Richard; Harrison, David; Steyerberg, Ewout; Eggo, Rosalind M; Diaz-Ordaz, Karla; Keogh, Ruth; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben

Factors associated with COVID-19-related death using OpenSAFELY. (2020) Williamson, Elizabeth J; Walker, Alex J; Bhaskaran, Krishnan; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; MacKenna, Brian; Tomlinson, Laurie; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Grieve, Richard; Harrison, David; Forbes, Harriet; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Rafael; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben

Improving the measurement and detection of serious adverse drug reactions in databases of stored electronic health records. (2016) Wing, Kevin

Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study. (2017) Wing, Kevin; Bhaskaran, Krishnan; Pealing, Louise; Root, Adrian; Smeeth, Liam; van Staa, Tjeerd P; Klungel, Olaf H; Reynolds, Robert F; Douglas, Ian

Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury. (2016) Wing, Kevin; Bhaskaran, Krishnan; Smeeth, Liam; van Staa, Tjeerd P; Klungel, Olaf H; Reynolds, Robert F; Douglas, Ian

Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records. (2013) Wing, Kevin; Douglas, Ian; Bhaskaran, Krishnan; Klungel, Olaf H; Reynolds, Robert F; Pirmohamed, Munir; Smeeth, Liam; van Staa, Tjeerd P

Association between household composition and severe COVID-19 outcomes in older people by ethnicity: an observational cohort study using the OpenSAFELY platform. (2022) Wing, Kevin; Grint, Daniel J; Mathur, Rohini; Gibbs, Hamish P; Hickman, George; Nightingale, Emily; Schultze, Anna; Forbes, Harriet; Nafilyan, Vahé; Bhaskaran, Krishnan; Williamson, Elizabeth; House, Thomas; Pellis, Lorenzo; Herrett, Emily; Gautam, Nileesa; Curtis, Helen J; Rentsch, Christopher T; Wong, Angel YS; MacKenna, Brian; Mehrkar, Amir; Bacon, Seb; Douglas, Ian J; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben; Eggo, Rosalind M

Medications for chronic obstructive pulmonary disease: a historical non-interventional cohort study with validation against RCT results. (2021) Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian

Real world effects of COPD medications: a cohort study with validation against results from randomised controlled trials. (2020) Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian

Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results. (2018) Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian

Cardiovascular outcomes associated with use of clarithromycin: population based study. (2016) Wong, Angel YS; Root, Adrian; Douglas, Ian J; Chui, Celine SL; Chan, Esther W; Ghebremichael-Weldeselassie, Yonas; Siu, Chung-Wah; Smeeth, Liam; Wong, Ian CK

Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19: an OpenSAFELY cohort analysis based on two cohorts. (2021) Wong, Angel Ys; MacKenna, Brian; Morton, Caroline E; Schultze, Anna; Walker, Alex J; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; OpenSAFELY Collaborative

Association between oral anticoagulants and COVID-19-related outcomes: a population-based cohort study. (2022) Wong, Angel Ys; Tomlinson, Laurie; Brown, Jeremy P; Elson, William; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Evans, David; Inglesby, Peter; MacKenna, Brian; Bhaskaran, Krishnan; Rentsch, Christopher T; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen I; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Evans, Stephen Jw; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J; (The OpenSAFELY Collaborative)

Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort. (2017) Yates, Tom A; Tomlinson, Laurie A; Bhaskaran, Krishnan; Langan, Sinead; Thomas, Sara; Smeeth, Liam; Douglas, Ian J

Signal Detection for Recently Approved Products: Adapting and Evaluating Self-Controlled Case Series Method Using a US Claims and UK Electronic Medical Records Database. (2018) Zhou, Xiaofeng; Douglas, Ian J; Shen, Rongjun; Bate, Andrew

Case-only designs for studying the association of antidepressants and hip or femur fracture. (2016) de Groot, MC; Candore, G; Uddin, MJ; Souverein, PC; Ali, MS; Belitser, SV; Huerta, C; Groenwold, RH; Alvarez, Y; Slattery, J; Korevaar, J; Hoes, AW; Roes, KC; de Boer, A; Douglas, IJ; Schlienger, RG; Reynolds, R; Klungel, OH; Gardarsdottir, H

Frailty and rate of fractures in patients initiating antihypertensive medications: a cohort study in primary care. (2022) Österdahl, Marc F; Sinnott, Sarah-Jo; Douglas, Ian; Clegg, Andrew; Tomlinson, Laurie; Wong, Angel

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COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis. (2020) Boddington, Nicola L; Charlett, Andre; Elgohari, Suzanne; Walker, Jemma L; Mcdonald, Helen; Byers, Chloe; Coughlan, Laura; Garcia Vilaplana, Tatiana; Whillock, Rosie; Sinnathamby, Mary; Panagiotopoulos, Nikolaos; Letley, Louise; MacDonald, Pauline; Vivancos, Roberto; Edeghere, Obaghe; Shingleton, Joseph; Bennett, Emma; Grint, Daniel J; Strongman, Helen; Mansfield, Kathryn E; Rentsch, Christopher; Minassian, Caroline; Douglas, Ian J; Mathur, Rohini; Peppa, Maria; Cottrell, Simon; McMenamin, Jim; Zambon, Maria; Ramsay, Mary; Dabrera, Gavin; Saliba, Vanessa; Lopez Bernal, Jamie picture_as_pdf

OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients. (2020) Williamson, Elizabeth; Walker, Alex J; Bhaskaran, Krishnan; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; MacKenna, Brian; Tomlinson, Laurie; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Grieve, Richard; Harrison, David; Forbes, Harriet; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Raf; Evans, Stephen; Smeeth, Liam; Goldacre, Ben description

OpenSAFELY: Do adults prescribed non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19? (2020) Wong, Angel YS; MacKenna, Brian; Morton, Caroline E; Schultze, Anna; Walker, Alex J; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben picture_as_pdf