Year Item Type Full Text

Article

Mitochondria: An Integrative Hub Coordinating Circadian Rhythms, Metabolism, the Microbiome, and Immunity. (2020) Aguilar-López, Bruno A; Moreno-Altamirano, María Maximina Bertha; Dockrell, Hazel M; Duchen, Michael R; Sánchez-García, Francisco Javier

Strain-dependent variation in Mycobacterium bovis BCG-induced human T-cell activation and gamma interferon production in vitro. (2007) Aguirre-Blanco, Ana M; Lukey, Pauline T; Cliff, Jacqueline M; Dockrell, Hazel M

Diagnosis of childhood tuberculosis and host RNA expression in Africa. (2014) Anderson, Suzanne T; Kaforou, Myrsini; Brent, Andrew J; Wright, Victoria J; Banwell, Claire M; Chagaluka, George; Crampin, Amelia C; Dockrell, Hazel M; French, Neil; Hamilton, Melissa S; Hibberd, Martin L; Kern, Florian; Langford, Paul R; Ling, Ling; Mlotha, Rachel; Ottenhoff, Tom HM; Pienaar, Sandy; Pillay, Vashini; Scott, J Anthony G; Twahir, Hemed; Wilkinson, Robert J; Coin, Lachlan J; Heyderman, Robert S; Levin, Michael; Eley, Brian ['material/summary:fileicon_text/html' not defined]

Report on the first meeting of the IDEAL (Initiative for Diagnostic and Epidemiological Assays for Leprosy) consortium held at Armauer Hansen Research Institute, ALERT, Addis Ababa, Ethiopia on 24-27 October 2004. (2005) Aseffa, Abraham; Brennan, Patrick; Dockrell, Hazel; Gillis, Tom; Hussain, Rabia; Oskam, Linda; Richardus, Jan Hendrik; Ideal Consortium

Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease. (2016) Awoniyi, DO; Teuchert, A; Sutherland, JS; Mayanja-Kizza, H; Howe, R; Mihret, A; Loxton, AG; Sheehama, J; Kassa, D; Crampin, AC; Dockrell, HM; Kidd, M; Rosenkrands, I; Geluk, A; Ottenhoff, TH; Corstjens, PL; Chegou, NN; Walzl, G; AE-TBC Consortium; COLLABORATORS; Walzl, G; Chegou, NN; Kriel, M; van der Spuy, G; Loxton, AG; Stanley, K; Malherbe, S; Mcanda, S; Kriel, B; Phalane, KG; Essone, P; Sutherland, JS; Owolabi, O; Sillah, A; Mendy, J; Gindeh, A; Donkor, S; Togun, T; Ota, M; Crampin, AC; Simukonda, F; Amberbir, A; Chilongo, F; Houben, R; Kassa, D; Gebrezgeabher, A; Mesfin, G; Belay, Y; Gebremichael, G; Alemayehu, Y; van der Vyver, M; Amutenya, FN; Nelongo, JN; Monye, L; Sheehama, JA; Iipinge, S; Mayanja-Kizza, H; Namuganga, AR; Muzanye, G; Nsereko, M; Peters, P; Howe, R; Mihret, A; Bekele, Y; Tessema, B; Yamuah, L; Ottenhoff, TH; Geluk, A; Franken, K; Corstjens, PL; Tjon Kon Fat, EM; de Dood, CJ; van der Ploeg-van Schip, JJ; Rosenkrands, I; Aagaard, C; Kaufmann, SH; Esterhuyse, MM; Cliff, JM; Dockrell, HM description

Differences between naive and memory T cell phenotype in Malawian and UK adolescents: a role for Cytomegalovirus? (2008) Ben-Smith, Anne; Gorak-Stolinska, Patricia; Floyd, Sian; Weir, Rosemary E; Lalor, Maeve K; Mvula, Hazzie; Crampin, Amelia C; Wallace, Diana; Beverley, Peter Cl; Fine, Paul Em; Dockrell, Hazel M picture_as_pdf

The PPD-specific T-cell clonal response in UK and Malawian subjects following BCG vaccination: a new repertoire evolves over 12 months. (2006) Bennett, Andrea R; Gorak-Stolinska, Patricia; Ben-Smith, Anne; Floyd, Sian; de Lara, Catherine M; Weir, Rosemary E; Lalor, Maeve K; Makamo, Kandakuone; Msiska, Glyn K; Crampin, Amelia C; Fine, Paul EM; Dockrell, Hazel M; Beverley, Peter CL

A comparison of IFNgamma detection methods used in tuberculosis vaccine trials. (2008) Beveridge, Natalie ER; Fletcher, Helen A; Hughes, Jane; Pathan, Ansar A; Scriba, Thomas J; Minassian, Angela; Sander, Clare R; Whelan, Kathryn T; Dockrell, Hazel M; Hill, Adrian VS; Hanekom, Willem A; McShane, Helen

Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort. (2014) Biraro, Irene A; Egesa, Moses; Toulza, Frederic; Levin, Jonathan; Cose, Stephen; Joloba, Moses; Smith, Steven; Dockrell, Hazel M; Katamba, Achilles; Elliott, Alison M

Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study. (2015) Biraro, Irene Andia; Egesa, Moses; Kimuda, Simon; Smith, Steven G; Toulza, Frederic; Levin, Jonathan; Joloba, Moses; Katamba, Achilles; Cose, Stephen; Dockrell, Hazel M; Elliott, Alison M

The Use of Interferon Gamma Inducible Protein 10 as a Potential Biomarker in the Diagnosis of Latent Tuberculosis Infection in Uganda. (2016) Biraro, Irene Andia; Kimuda, Simon; Egesa, Moses; Cose, Stephen; Webb, Emily L; Joloba, Moses; Smith, Steven G; Elliott, Alison M; Dockrell, Hazel M; Katamba, Achilles

Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern Malawi. (2001) Black, GF; Dockrell, HM; Crampin, AC; Floyd, S; Weir, RE; Bliss, L; Sichali, L; Mwaungulu, L; Kanyongoloka, H; Ngwira, B; Warndorff, DK; Fine, PE

Relationship between IFN-gamma and skin test responsiveness to Mycobacterium tuberculosis PPD in healthy, non-BCG-vaccinated young adults in Northern Malawi. (2001) Black, GF; Fine PEM; Warndorff, DK; Floyd, S; Weir, RE; Blackwell, JM; Bliss, L; Sichali, L; Mwaungulu, L; Chaguluka, S; Jarman, E; Ngwira, B; Dockrell, HM

Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa. (2009) Black, Gillian F; Thiel, Bonnie A; Ota, Martin O; Parida, Shreemanta K; Adegbola, Richard; Boom, W Henry; Dockrell, Hazel M; Franken, Kees LMC; Friggen, Annemiek H; Hill, Philip C; Klein, Michel R; Lalor, Maeve K; Mayanja, Harriet; Schoolnik, Gary; Stanley, Kim; Weldingh, Karin; Kaufmann, Stefan HE; Walzl, Gerhard; Ottenhoff, Tom HM; GCGH Biomarkers for TB Consortium

Gamma interferon responses induced by a panel of recombinant and purified mycobacterial antigens in healthy, non-mycobacterium bovis BCG-vaccinated Malawian young adults. (2003) Black, Gillian F; Weir, Rosemary E; Chaguluka, Steven D; Warndorff, David; Crampin, Amelia C; Mwaungulu, Lorren; Sichali, Lifted; Floyd, Sian; Bliss, Lyn; Jarman, Elizabeth; Donovan, Linda; Andersen, Peter; Britton, Warwick; Hewinson, Glyn; Huygen, Kris; Paulsen, Jens; Singh, Mahavir; Prestidge, Ross; Fine, Paul EM; Dockrell, Hazel M

BCG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK: two randomised controlled studies. (2002) Black, Gillian F; Weir, Rosemary E; Floyd, Sian; Bliss, Lyn; Warndorff, David K; Crampin, Amelia C; Ngwira, Bagrey; Sichali, Lifted; Nazareth, Bernadette; Blackwell, Jenefer M; Branson, Keith; Chaguluka, Steven D; Donovan, Linda; Jarman, Elizabeth; King, Elizabeth; Fine, Paul EM; Dockrell, Hazel M

Human T cell responses to peptides of the Mycobacterium leprae 45-kD serine-rich antigen. (2002) Brahmbhatt, S; Hussain, R; Zafar, S; Dawood, G; Ottenhoff, THM; Drijfhout, JW; Bothamley, G; Smith, S; Lopez, FV; Dockrell, HM

Screening vaccine formulations for biological activity using fresh human whole blood. (2014) Brookes, Roger H; Hakimi, Jalil; Ha, Yukyung; Aboutorabian, Sepideh; Ausar, Salvador F; Hasija, Manvi; Smith, Steven G; Todryk, Stephen M; Dockrell, Hazel M; Rahman, Nausheen

Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection. (2007) Cehovin, Ana; Cliff, Jacqueline M; Hill, Philip C; Brookes, Roger H; Dockrell, Hazel M

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB. (2016) Chegou, NN; Sutherland, JS; Malherbe, S; Crampin, AC; Corstjens, PL; Geluk, A; Mayanja-Kizza, H; Loxton, AG; van der Spuy, G; Stanley, K; Kotzé, LA; van der Vyver, M; Rosenkrands, I; Kidd, M; van Helden, PD; Dockrell, HM; Ottenhoff, TH; Kaufmann, SH; Walzl, G; AE-TBC consortium; COLLABORATORS; Kriel, M; Malherbe, S; Kriel, B; Awoniyi, DO; Maasdorp, E; Owolabi, O; Sillah, A; Mendy, J; Gindeh, A; Donkor, S; Togun, T; Ota, M; Simukonda, F; Amberbir, A; Chilongo, F; Houben, R; Kassa, D; Gebrezgeabher, A; Mesfin, G; Belay, Y; Gebremichael, G; Alemayehu, Y; Amutenya, FN; Nelongo, JN; Monye, L; Sheehama, JA; Iipinge, S; Namuganga, AR; Muzanye, G; Nsereko, M; Peters, P; Howe, R; Mihret, A; Bekele, Y; Tessema, B; Yamuah, L; Ottenhoff, TH; Franken, KL; Corstjens, PL; Fat, EM; de Dood, CJ; van der Ploeg-van Schip, JJ; Aagaard, C; Kaufmann, SH; Esterhuyse, MM; Cliff, JM description

Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis. (2018) Chegou, Novel N; Sutherland, Jayne S; Namuganga, Anna-Ritah; Corstjens, Paul Lam; Geluk, Annemieke; Gebremichael, Gebremedhin; Mendy, Joseph; Malherbe, Stephanus; Stanley, Kim; van der Spuy, Gian D; Kriel, Magdalena; Loxton, Andre G; Kriel, Belinda; Simukonda, Felanji; Bekele, Yonas; Sheehama, Jacob A; Nelongo, Josefina; van der Vyver, Marieta; Gebrexabher, Atsbeha; Hailu, Habteyes; Esterhuyse, Maria M; Rosenkrands, Ida; Aagard, Claus; Kidd, Martin; Kassa, Desta; Mihret, Adane; Howe, Rawleigh; Cliff, Jacqueline M; Crampin, Amelia C; Mayanja-Kizza, Harriet; Kaufmann, Stefan HE; Dockrell, Hazel M; Ottenhoff, Tom HM; Walzl, Gerhard; AE-TBC consortium

Differential gene expression identifies novel markers of CD4+ and CD8+ T cell activation following stimulation by Mycobacterium tuberculosis. (2004) Cliff, Jacqueline M; Andrade, Iryna NJ; Mistry, Rohit; Clayton, Christopher L; Lennon, Mark G; Lewis, Alan P; Duncan, Ken; Lukey, Pauline T; Dockrell, Hazel M

Excessive Cytolytic Responses Predict Tuberculosis Relapse After Apparently Successful Treatment. (2015) Cliff, Jacqueline M; Cho, Jang-Eun; Lee, Ji-Sook; Ronacher, Katharina; King, Elizabeth C; van Helden, Paul; Walzl, Gerhard; Dockrell, Hazel M

Cellular Immune Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). (2019) Cliff, Jacqueline M; King, Elizabeth C; Lee, Ji-Sook; Sepúlveda, Nuno; Wolf, Asia-Sophia; Kingdon, Caroline; Bowman, Erinna; Dockrell, Hazel M; Nacul, Luis; Lacerda, Eliana; Riley, Eleanor M

Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response. (2012) Cliff, Jacqueline M; Lee, Ji-Sook; Constantinou, Nicholas; Cho, Jang-Eun; Clark, Taane G; Ronacher, Katharina; King, Elizabeth C; Lukey, Pauline T; Duncan, Ken; Van Helden, Paul D; Walzl, Gerhard; Dockrell, Hazel M

Gamma interferon - Key, but not sufficient for protection against TB? (2007) Dockrell, HM

Roitt's essential immunology: book review. (2002) Dockrell, HM

Reply. (2002) Dockrell, HM; Black, GF; Weir, RE; Fine, PEM

Presidential address: the role of research networks in tackling major challenges in international health. (2010) Dockrell, Hazel M

Towards new TB vaccines: What are the challenges? (2016) Dockrell, Hazel M

Keep the faith--leprosy still needs new diagnostic tools and laboratory research. (2011) Dockrell, Hazel M

Another step down the development pipeline for the novel tuberculosis vaccine MVA-85A. (2011) Dockrell, Hazel M

Real vaccines in the real world: tuberculosis vaccines move south. (2008) Dockrell, Hazel M

A new challenge for the tuberculosis vaccine community? (2012) Dockrell, Hazel M

One Health--'joining the dots'. (2012) Dockrell, Hazel M ['material/summary:fileicon_text/html' not defined]

Working together toward vaccines and biomarkers in the real world. (2017) Dockrell, Hazel M

Can what have we learnt about BCG vaccination in the last 20 years help us to design a better tuberculosis vaccine? (2021) Dockrell, Hazel M; Butkeviciute, Egle

Report on the sixth meeting of the IDEAL (Initiative for Diagnostic and Epidemiological Assays for Leprosy) consortium held in Beijing, China on 23-25 August 2010. (2011) Dockrell, Hazel M; Geluk, Annemieke; Brennan, Patrick; Saunderson, Paul R; Oskam, Linda; Lockwood, Diana N; Xiaoman, Weng; Richardus, Jan Hendrik

Tuberculosis vaccines in the era of Covid-19 - what is taking us so long? (2022) Dockrell, Hazel M; McShane, Helen

Global collaborations in leprosy research--the future is connected. (2008) Dockrell, Hazel M; Oskam, Linda; Richardus, Jan Hendrik

What Have We Learnt about BCG Vaccination in the Last 20 Years? (2017) Dockrell, Hazel M; Smith, Steven G

Variability between countries in cytokine responses to BCG vaccination: what impact might this have on protection? (2012) Dockrell, Hazel M; Smith, Steven G; Lalor, Maeve K

A courageous step down the road toward a new tuberculosis vaccine. (2009) Dockrell, Hazel M; Zhang, Ying

A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts. (2018) Duffy, Fergal J; Thompson, Ethan; Downing, Katrina; Suliman, Sara; Mayanja-Kizza, Harriet; Boom, W Henry; Thiel, Bonnie; Weiner Iii, January; Kaufmann, Stefan HE; Dover, Drew; Tabb, David L; Dockrell, Hazel M; Ottenhoff, Tom HM; Tromp, Gerard; Scriba, Thomas J; Zak, Daniel E; Walzl, Gerhard; GC6-74 Consortium

Impact of Intermediate Hyperglycemia and Diabetes on Immune Dysfunction in Tuberculosis. (2021) Eckold, Clare; Kumar, Vinod; Weiner, January; Alisjahbana, Bachti; Riza, Anca-Lelia; Ronacher, Katharina; Coronel, Jorge; Kerry-Barnard, Sarah; Malherbe, Stephanus T; Kleynhans, Leanie; Stanley, Kim; Ruslami, Rovina; Ioana, Mihai; Ugarte-Gil, Cesar; Walzl, Gerhard; van Crevel, Reinout; Wijmenga, Cisca; Critchley, Julia A; Dockrell, Hazel M; Cliff, Jacqueline M; TANDEM consortium

The immune response to Mycobacterium tuberculosis in HIV-infected and uninfected adults in Uganda: application of a whole blood cytokine assay in an epidemiological study. (2001) Elliott, AM; Hurst, TJ; Balyeku, MN; Quigley, MA; Kaleebu, P; French, N; Biryahwaho, B; Whitworth, JA; Dockrell, HM; Hayes, RJ

Cytokine responses and progression to active tuberculosis in HIV-1-infected Ugandans: a prospective study. (2004) Elliott, Alison M; Hodsdon, Wendy S; Kyosiimire, Jacqueline; Quigley, Maria A; Nakiyingi, Jessica S; Namujju, Proscovia B; Watera, Christine; French, Neil; Gilks, Charles F; Dockrell, Hazel M; Whitworth, James AG

Interferon-gamma responses to ESAT-6 in tuberculosis patients early into and after anti-tuberculosis treatment. (2005) Ferrand, RA; Bothamley, GH; Whelan, A; Dockrell, HM

Human biomarkers: can they help us to develop a new tuberculosis vaccine? (2016) Fletcher, Helen A; Dockrell, Hazel M

Inhibition of mycobacterial growth in vitro following primary but not secondary vaccination with Mycobacterium bovis BCG. (2013) Fletcher, Helen A; Tanner, Rachel; Wallis, Robert S; Meyer, Joel; Manjaly, Zita-Rose; Harris, Stephanie; Satti, Iman; Silver, Richard F; Hoft, Dan; Kampmann, Beate; Walker, K Barry; Dockrell, Hazel M; Fruth, Uli; Barker, Lew; Brennan, Michael J; McShane, Helen

Analysis of data from individuals demonstrates high discordance between IFN-gamma assays and PPD-tuberculin skin tests used in screening for tuberculosis infection - In reply. (2002) Floyd, S; Black, GF; Dockrell, HM; Fine, PEM

New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy. (2012) Geluk, Annemieke; Bobosha, Kidist; van der Ploeg-van Schip, Jolien J; Spencer, John S; Banu, Sayera; Martins, Marcia VSB; Cho, Sang-Nae; Franken, Kees LMC; Kim, Hee Jin; Bekele, Yonas; Uddin, Mohammad KM; Hadi, Sheikh Abdul; Aseffa, Abraham; Pessolani, Maria CV; Pereira, Geraldo MB; Dockrell, Hazel M; Ottenhoff, Tom HM

From genome-based in silico predictions to ex vivo verification of leprosy diagnosis. (2009) Geluk, Annemieke; Spencer, John S; Bobosha, Kidist; Pessolani, Maria CV; Pereira, Geraldo MB; Banu, Sayera; Honoré, Nadine; Reece, Stephen T; MacDonald, Murdo; Sapkota, Bishwa Raj; Ranjit, Chaman; Franken, Kees LMC; Zewdie, Martha; Aseffa, Abraham; Hussain, Rabia; Stefani, Mariane M; Cho, Sang-Nae; Oskam, Linda; Brennan, Patrick J; Dockrell, Hazel M; IDEAL Consortium

Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification. (2021) Gliddon, Harriet D; Kaforou, Myrsini; Alikian, Mary; Habgood-Coote, Dominic; Zhou, Chenxi; Oni, Tolu; Anderson, Suzanne T; Brent, Andrew J; Crampin, Amelia C; Eley, Brian; Heyderman, Robert; Kern, Florian; Langford, Paul R; Ottenhoff, Tom HM; Hibberd, Martin L; French, Neil; Wright, Victoria J; Dockrell, Hazel M; Coin, Lachlan J; Wilkinson, Robert J; Levin, Michael

Immunogenicity of Danish-SSI 1331 BCG vaccine in the UK: comparison with Glaxo-Evans 1077 BCG vaccine. (2006) Gorak-Stolinska, Patricia; Weir, Rosemary E; Floyd, Sian; Lalor, Maeve K; Stenson, Sally; Branson, Keith; Blitz, Rose; Luke, Sarah; Nazareth, Bernadette; Ben-Smith, Anne; Fine, Paul EM; Dockrell, Hazel M

Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa. (2018) Grint, Daniel; Alisjhabana, Bachti; Ugarte-Gil, Cesar; Riza, Anca-Leila; Walzl, Gerhard; Pearson, Fiona; Ruslami, Rovina; Moore, David AJ; Ioana, Mihai; McAllister, Susan; Ronacher, Katharina; Koeseomadinata, Raspati C; Kerry-Barnard, Sarah R; Coronel, Jorge; Malherbe, Stephanus T; Dockrell, Hazel M; Hill, Philip C; Van Crevel, Reinout; Critchley, Julia A; TANDEM consortium

Building research capacity through international partnerships. (2009) Haines, Andy; Dockrell, Hazel

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations. (2008) Hanekom, Willem A; Dockrell, Hazel M; Ottenhoff, Tom HM; Doherty, T Mark; Fletcher, Helen; McShane, Helen; Weichold, Frank F; Hoft, Dan F; Parida, Shreemanta K; Fruth, Uli J

CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis. (2009) Hasan, Zahra; Cliff, Jacqueline M; Dockrell, Hazel M; Jamil, Bushra; Irfan, Muhammad; Ashraf, Mussarat; Hussain, Rabia

PD-1, PD-L1 and PD-L2 Gene Expression on T-Cells and Natural Killer Cells Declines in Conjunction with a Reduction in PD-1 Protein during the Intensive Phase of Tuberculosis Treatment. (2015) Hassan, Syeda S; Akram, Muhammad; King, Elizabeth C; Dockrell, Hazel M; Cliff, Jacqueline M

Modulation of NKG2D expression in human CD8(+) T cells corresponding with tuberculosis drug cure. (2013) Hassan, Syeda S; Cho, Jang-Eun; Akram, Muhammad; Fielding, Katherine L; Dockrell, Hazel M; Cliff, Jacqueline M

Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination. (2018) Hasso-Agopsowicz, Mateusz; Scriba, Thomas J; Hanekom, Willem A; Dockrell, Hazel M; Smith, Steven G

The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection. (2006) Holland, Martin J; Faal, Nkoyo; Sarr, Isatou; Joof, Hassan; Laye, Mass; Cameron, Ewen; Pemberton-Pigott, Frederick; Dockrell, Hazel M; Bailey, Robin L; Mabey, David CW

Screening for Mycobacterium tuberculosis Infection Using Beijing/K Strain-Specific Peptides in a School Outbreak Cohort. (2021) Hong, Ji Young; Kim, Ahreum; Park, So Yeong; Cho, Sang-Nae; Dockrell, Hazel M; Hur, Yun-Gyoung

A Feasibility Study for Diagnosis of Latent Tuberculosis Infection Using an IGRA Point-of-Care Platform in South Korea. (2019) Hur, Yun Gyoung; Hong, Ji Young; Choi, Dong Hwan; Kim, Ahreum; Park, So Yeong; Kwon, Minsuk; Kang, Kyungjoon; Lee, Jeong Min; Dockrell, Hazel M; Lee, Yoonsuk; Joo, Hoodon; Cho, Sang Nae

Identification of immunological biomarkers which may differentiate latent tuberculosis from exposure to environmental nontuberculous mycobacteria in children. (2013) Hur, Yun-Gyoung; Crampin, Amelia C; Chisambo, Christina; Kanyika, James; Houben, Rein; Ndhlovu, Richard; Mzembe, Themba; Lalor, Maeve K; Saul, Jacky; Branson, Keith; Stanley, Carolynne; Ngwira, Bagrey; French, Neil; Ottenhoff, Tom H; Dockrell, Hazel M; Gorak-Stolinska, Patricia

Combination of cytokine responses indicative of latent TB and active TB in Malawian adults. (2013) Hur, Yun-Gyoung; Gorak-Stolinska, Patricia; Ben-Smith, Anne; Lalor, Maeve K; Chaguluka, Steven; Dacombe, Russell; Doherty, T Mark; Ottenhoff, Tom H; Dockrell, Hazel M; Crampin, Amelia C

Factors affecting immunogenicity of BCG in infants, a study in Malawi, The Gambia and the UK. (2014) Hur, Yun-Gyoung; Gorak-Stolinska, Patricia; Lalor, Maeve K; Mvula, Hazzie; Floyd, Sian; Raynes, John; Ben-Smith, Anne; Fitchett, Joseph R; Flanagan, Katie L; Burl, Sarah; Ota, Martin O; Crampin, Amelia C; Smith, Steven G; Dockrell, Hazel M

Cytokine profiles using whole-blood assays can discriminate between tuberculosis patients and healthy endemic controls in a BCG-vaccinated population. (2002) Hussain, Rabia; Kaleem, Arnawaz; Shahid, Firdaus; Dojki, Maqboola; Jamil, Bushra; Mehmood, Hammad; Dawood, Ghaffar; Dockrell, Hazel M

Immune profiling of leprosy and tuberculosis patients to 15-mer peptides of Mycobacterium leprae and M. tuberculosis GroES in a BCG vaccinated area: implications for development of vaccine and diagnostic reagents. (2004) Hussain, Rabia; Shahid, Firdaus; Zafar, Shahid; Dojki, Maqboola; Dockrell, Hazel M

Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines and FoxP3 Expressing Treg Cells in Pulmonary TB. (2013) Jackson-Sillah, Dolly; Cliff, Jacqueline M; Mensah, Gloria Ivy; Dickson, Emmanuel; Sowah, Sandra; Tetteh, John KA; Addo, Kwasi K; Ottenhoff, Tom HM; Bothamley, Graham; Dockrell, Hazel M

Dynamics of cytokine generation in patients with active pulmonary tuberculosis. (2003) Jo, Eun-Kyeong; Park, Jeong-Kyu; Dockrell, Hazel M

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study. (2013) Kaforou, Myrsini; Wright, Victoria J; Oni, Tolu; French, Neil; Anderson, Suzanne T; Bangani, Nonzwakazi; Banwell, Claire M; Brent, Andrew J; Crampin, Amelia C; Dockrell, Hazel M; Eley, Brian; Heyderman, Robert S; Hibberd, Martin L; Kern, Florian; Langford, Paul R; Ling, Ling; Mendelson, Marc; Ottenhoff, Tom H; Zgambo, Femia; Wilkinson, Robert J; Coin, Lachlan J; Levin, Michael

Isolation and Potential for Transmission of Mycobacterium bovis at Human-livestock-wildlife Interface of the Serengeti Ecosystem, Northern Tanzania. (2015) Katale, BZ; Mbugi, EV; Siame, KK; Keyyu, JD; Kendall, S; Kazwala, RR; Dockrell, HM; Fyumagwa, RD; Michel, AL; Rweyemamu, M; Streicher, EM; Warren, RM; van Helden, P; Matee, MI ['material/summary:fileicon_application/msword' not defined]

Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania. (2020) Katale, Bugwesa Z; Mbelele, Peter M; Lema, Nsiande A; Campino, Susana; Mshana, Stephen E; Rweyemamu, Mark M; Phelan, Jody E; Keyyu, Julius D; Majigo, Mtebe; Mbugi, Erasto V; Dockrell, Hazel M; Clark, Taane G; Matee, Mecky I; Mpagama, Stellah

Species diversity of non-tuberculous mycobacteria isolated from humans, livestock and wildlife in the Serengeti ecosystem, Tanzania. (2014) Katale, Bugwesa Z; Mbugi, Erasto V; Botha, Louise; Keyyu, Julius D; Kendall, Sharon; Dockrell, Hazel M; Michel, Anita L; Kazwala, Rudovick R; Rweyemamu, Mark M; van Helden, Paul; Matee, Mecky I ['material/summary:fileicon_text/html' not defined]

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development. (2017) Kaufmann, Stefan HE; Dockrell, Hazel M; Drager, Nick; Ho, Mei Mei; McShane, Helen; Neyrolles, Olivier; Ottenhoff, Tom HM; Patel, Brij; Roordink, Danielle; Spertini, François; Stenger, Steffen; Thole, Jelle; Verreck, Frank AW; Williams, Ann; TBVAC2020 Consortium

Diagnostic Potential of a PPE Protein Derived from Mycobacterium tuberculosis Beijing/K Strain. (2020) Kim, Ahreum; Park, Kwang Joo; Kim, Young Sun; Cho, Sang Nae; Dockrell, Hazel M; Hur, Yun Gyoung

Mycobacterial load affects adenosine deaminase 2 levels of tuberculous pleural effusion. (2015) Kim, Chang Ho; Lee, Jaehee; Lee, Jisook; Cliff, Jacqueline M; Toulza, Frederic; Smith, Steven; Yoo, Seung Soo; Lee, Shin Yup; Cha, Seung Ick; Park, Jae Yong; Dockrell, Hazel M

The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis. (2017) Lacerda, Eliana M; Bowman, Erinna W; Cliff, Jacqueline M; Kingdon, Caroline C; King, Elizabeth C; Lee, Ji-Sook; Clark, Taane G; Dockrell, Hazel M; Riley, Eleanor M; Curran, Hayley; Nacul, Luis

Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects. (2019) Lachmandas, Ekta; Eckold, Clare; Böhme, Julia; Koeken, Valerie ACM; Marzuki, Mardiana Binte; Blok, Bastiaan; Arts, Rob JW; Chen, Jinmiao; Teng, Karen WW; Ratter, Jacqueline; Smolders, Elise J; Van den Heuvel, Corina; Stienstra, Rinke; Dockrell, Hazel M; Newell, Evan; Netea, Mihai G; Singhal, Amit; Cliff, Jacqueline M; Van Crevel, Reinout

Population differences in immune responses to Bacille Calmette-Guérin vaccination in infancy. (2009) Lalor, Maeve K; Ben-Smith, Anne; Gorak-Stolinska, Patricia; Weir, Rosemary E; Floyd, Sian; Blitz, Rose; Mvula, Hazzie; Newport, Melanie J; Branson, Keith; McGrath, Nuala; Crampin, Amelia C; Fine, Paul EM; Dockrell, Hazel M

BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi. (2011) Lalor, Maeve K; Floyd, Sian; Gorak-Stolinska, Patricia; Ben-Smith, Anne; Weir, Rosemary E; Smith, Steven G; Newport, Melanie J; Blitz, Rose; Mvula, Hazzie; Branson, Keith; McGrath, Nuala; Crampin, Amelia C; Fine, Paul E; Dockrell, Hazel M

BCG vaccination: a role for vitamin D? (2011) Lalor, Maeve K; Floyd, Sian; Gorak-Stolinska, Patricia; Weir, Rosemary E; Blitz, Rose; Branson, Keith; Fine, Paul E; Dockrell, Hazel M

Complex cytokine profiles induced by BCG vaccination in UK infants. (2009) Lalor, Maeve K; Smith, Steven G; Floyd, Sian; Gorak-Stolinska, Patricia; Weir, Rosemary E; Blitz, Rose; Branson, Keith; Fine, Paul E; Dockrell, Hazel M

Utility of interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa. (2007) Lawn, Stephen D; Bangani, Nonzwakazi; Vogt, Monica; Bekker, Linda-Gail; Badri, Motasim; Ntobongwana, Marjorie; Dockrell, Hazel M; Wilkinson, Robert J; Wood, Robin picture_as_pdf

Health care workers who are to progress to active TB disease present a panel of T cell immune markers predicting such progression. (2004) Leandro, C; Ordway, D; Martins, MS; Viveiros, M; Pinto, L; Arroz, MJ; Ventura, FA; Dockrell, HM; Amaral, L

Evaluation of cell-mediated immune responses to two BCG vaccination regimes in young children in South Korea. (2011) Lee, Hyejon; Cho, Sang Nae; Kim, Hee Jin; Anh, Young Min; Choi, Ji Eun; Kim, Chang Hwi; Ock, Park Jae; Oh, Sung Hee; Kim, Deok Ryun; Floyd, Sian; Dockrell, Hazel M

The Current Status of BCG Vaccination in Young Children in South Korea. (2012) Lee, Hyejon; Dockrell, Hazel M; Kim, Deok Ryun; Floyd, Sian; Oh, Sue Yeon; Lee, Jin Bum; Kim, Hee Jin

In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection. (2019) Lee, Hyejon; Kim, Jungho; Kang, Young Ae; Kim, Deok Ryun; Sim, Bora; Zelmer, Andrea; Fletcher, Helen A; Dockrell, Hazel M; Smith, Steven G; Cho, Sang-Nae

Addressing diversity in tuberculosis using multidimensional approaches. (2018) Lerm, M; Dockrell, HM

Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. (2007) Lin, May Young; Geluk, Annemieke; Smith, Steven G; Stewart, Amanda L; Friggen, Annemieke H; Franken, Kees LMC; Verduyn, Marleen JC; van Meijgaarden, Krista E; Voskuil, Martin I; Dockrell, Hazel M; Huygen, Kris; Ottenhoff, Tom HM; Klein, Michèl R

Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda. (2020) Lubyayi, Lawrence; Mawa, Patrice A; Nabakooza, Grace; Nakibuule, Marjorie; Tushabe, John Vianney; Serubanja, Joel; Aibo, Dorothy; Akurut, Hellen; Tumusiime, Josephine; Hasso-Agopsowicz, Mateusz; Kaleebu, Pontiano; Levin, Jonathan; Dockrell, Hazel M; Smith, Steven; Webb, Emily L; Elliott, Alison M; Cose, Stephen

Presence of human T-cell responses to the Mycobacterium leprae 45-kilodalton antigen reflects infection with or exposure to M. leprae. (2001) Macfarlane, A; Mondragon-Gonzalez, R; Vega-Lopez, F; Wieles, B; de Pena, J; Rodriguez, O; Suarez y de la Torre, R; de Vries, RR; Ottenhoff, TH; Dockrell, HM

Immune Responses Following BCG Immunization of Infants in Uganda and United Kingdom Are Similar for Purified Protein Derivative but Differ for Secretory Proteins of Mycobacterium tuberculosis. (2021) Mawa, Patrice A; Hasso-Agopsowicz, Mateusz; Lubyayi, Lawrence; Nabakooza, Grace; Nakibuule, Marjorie; Blitz, Rose; Dun, Li; Govind, Abha; Kaleebu, Pontiano; Webb, Emily L; Elliott, Alison M; Dockrell, Hazel M; Cose, Stephen; Smith, Steven G

The impact of maternal infection with Mycobacterium tuberculosis on the infant response to bacille Calmette-Guérin immunization. (2015) Mawa, Patrice A; Nkurunungi, Gyaviira; Egesa, Moses; Webb, Emily L; Smith, Steven G; Kizindo, Robert; Akello, Mirriam; Lule, Swaib A; Muwanga, Moses; Dockrell, Hazel M; Cose, Stephen; Elliott, Alison M

Maternal BCG scar is associated with increased infant proinflammatory immune responses. (2016) Mawa, Patrice Akusa; Webb, Emily L; Filali-Mouhim, Abdelali; Nkurunungi, Gyaviira; Sekaly, Rafick-Pierre; Lule, Swaib Abubaker; Prentice, Sarah; Nash, Stephen; Dockrell, Hazel M; Elliott, Alison M; Cose, Stephen

Genetic diversity of Mycobacterium tuberculosis isolated from tuberculosis patients in the Serengeti ecosystem in Tanzania. (2014) Mbugi, Erasto V; Katale, Bugwesa Z; Siame, Keith K; Keyyu, Julius D; Kendall, Sharon L; Dockrell, Hazel M; Streicher, Elizabeth M; Michel, Anita L; Rweyemamu, Mark M; Warren, Robin M; Matee, Mecky I; van Helden, Paul D

Mapping of Mycobacterium tuberculosis Complex Genetic Diversity Profiles in Tanzania and Other African Countries. (2016) Mbugi, Erasto V; Katale, Bugwesa Z; Streicher, Elizabeth M; Keyyu, Julius D; Kendall, Sharon L; Dockrell, Hazel M; Michel, Anita L; Rweyemamu, Mark M; Warren, Robin M; Matee, Mecky I; van Helden, Paul D; Couvin, David; Rastogi, Nalin

Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome. (2019) Melvin, A; Lacerda, E; Dockrell, HM; O'Rahilly, S; Nacul, L

Gene-expression patterns in whole blood identify subjects at risk for recurrent tuberculosis. (2007) Mistry, Rohit; Cliff, Jacqueline M; Clayton, Christopher L; Beyers, Nulda; Mohamed, Yasmin S; Wilson, Paul A; Dockrell, Hazel M; Wallace, Don M; van Helden, Paul D; Duncan, Ken; Lukey, Pauline T

Evaluation of Host Serum Protein Biomarkers of Tuberculosis in sub-Saharan Africa. (2021) Morris, Thomas C; Hoggart, Clive J; Chegou, Novel N; Kidd, Martin; Oni, Tolu; Goliath, Rene; Wilkinson, Katalin A; Dockrell, Hazel M; Sichali, Lifted; Banda, Louis; Crampin, Amelia C; French, Neil; Walzl, Gerhard; Levin, Michael; Wilkinson, Robert J; Hamilton, Melissa S

Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease. (2021) Mutavhatsindi, Hygon; van der Spuy, Gian D; Malherbe, Stephanus T; Sutherland, Jayne S; Geluk, Annemieke; Mayanja-Kizza, Harriet; Crampin, Amelia C; Kassa, Desta; Howe, Rawleigh; Mihret, Adane; Sheehama, Jacob A; Nepolo, Emmanuel; Günther, Gunar; Dockrell, Hazel M; Corstjens, Paul LAM; Stanley, Kim; Walzl, Gerhard; Chegou, Novel N; AE-TBC ScreenTB Consortia

Cytokine production and lymphocyte proliferation in patients with Nocardia brasiliensis actinomycetoma. (2004) Méndez-Tovar, Luis J; Mondragón-González, Rafael; Vega-López, Francisco; Dockrell, Hazel M; Hay, Roderick; López-Martínez, Rubén; Manzano-Gayosso, Patricia; Hernández-Hernández, Francisca; Padilla-Desgarennes, Carmen; Bonifaz, Alexandro

How Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Progresses: The Natural History of ME/CFS. (2020) Nacul, Luis; O'Boyle, Shennae; Palla, Luigi; Nacul, Flavio E; Mudie, Kathleen; Kingdon, Caroline C; Cliff, Jacqueline M; Clark, Taane G; Dockrell, Hazel M; Lacerda, Eliana M

Evidence of Clinical Pathology Abnormalities in People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) from an Analytic Cross-Sectional Study. (2019) Nacul, Luis; de Barros, Barbara; Kingdon, Caroline C; Cliff, Jacqueline M; Clark, Taane G; Mudie, Kathleen; Dockrell, Hazel M; Lacerda, Eliana M

Regulatory T cells in erythema nodosum leprosum maintain anti-inflammatory function. (2022) Negera, Edessa; Bobosha, Kidist; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana NJ; Walker, Stephen L

New Insight into the Pathogenesis of Erythema Nodosum Leprosum: The Role of Activated Memory T-Cells. (2017) Negera, Edessa; Bobosha, Kidist; Walker, Stephen L; Endale, Birtukan; Howe, Rawleigh; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions. (2018) Negera, Edessa; Tilahun, Melaku; Bobosha, Kidist; Lambert, Saba M; Walker, Stephen L; Spencer, John S; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

Increased activated memory B-cells in the peripheral blood of patients with erythema nodosum leprosum reactions. (2017) Negera, Edessa; Walker, Stephen L; Bekele, Yonas; Dockrell, Hazel M; Lockwood, Diana N

The Effects of Prednisolone Treatment on Cytokine Expression in Patients with Erythema Nodosum Leprosum Reactions. (2018) Negera, Edessa; Walker, Stephen L; Bobosha, Kidist; Bekele, Yonas; Endale, Birtukan; Tarekegn, Azeb; Abebe, Markos; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

T-cell regulation in Erythema Nodosum Leprosum. (2017) Negera, Edessa; Walker, Stephen L; Bobosha, Kidist; Howe, Rawleigh; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

Clinico-pathological features of erythema nodosum leprosum: A case-control study at ALERT hospital, Ethiopia. (2017) Negera, Edessa; Walker, Stephen L; Girma, Selfu; Doni, Shimelis N; Tsegaye, Degafe; Lambert, Saba M; Idriss, Munir H; Tsegay, Yohanis; Dockrell, Hazel M; Aseffa, Abraham; Lockwood, Diana N

Complement C1q expression in Erythema nodosum leprosum. (2018) Negera, Edessa; Walker, Stephen L; Lema, Tsehaynesh; Aseffa, Abraham; Lockwood, Diana N; Dockrell, Hazel M

A Natural History of Disease Framework for Improving the Prevention, Management, and Research on Post-viral Fatigue Syndrome and Other Forms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. (2022) O'Boyle, Shennae; Nacul, Luis; Nacul, Flavio E; Mudie, Kathleen; Kingdon, Caroline C; Cliff, Jacqueline M; Clark, Taane G; Dockrell, Hazel M; Lacerda, Eliana M

Respostas das citocinas T2 desencadeadas por Mycobacterium tuberculosis virulento now doentes com tuberculose pulmonar en estado avancado. (2001) Ordway, DJ; Arroz, MJ; Freire, MS; Dockrell, HM; Fernando, A; Ventura, FAAN

Comparacao das respostas celulares imunes induzidas por proteinas filtradas da cultura de Mycobacterium tuberculosis [Comparison of human cellular immune responses elicited by culture filtrate proteins of Mycobacterium tuberculosis]. (2001) Ordway, DJ; Silveira, H; Costa, L; Costa, S; Martins, M; Badura, R; Arroz, MJ; Dockrell, HM; Young, S; Ventura, FAAN

Increased Interleukin-4 production by CD8 and gammadelta T cells in health-care workers is associated with the subsequent development of active tuberculosis. (2004) Ordway, Diane J; Costa, Leonor; Martins, Marta; Silveira, Henrique; Amaral, Leonard; Arroz, Maria J; Ventura, Fernando A; Dockrell, Hazel M

[Increased IL-4 production in response to virulent Mycobacterium tuberculosis in tuberculosis patients with advanced disease]. (2005) Ordway, Diane J; Martins, Marta S; Costa, Leonor M; Freire, Mónica S; Arroz, Maria J; Dockrell, Hazel M; Ventura, Fernando A

Gamma delta T cell responses associated with the development of tuberculosis in health care workers. (2005) Ordway, Diane J; Pinto, Luisa; Costa, Leonor; Martins, Marta; Leandro, Clara; Viveiros, Miguel; Amaral, Leonard; Arroz, Maria J; Ventura, Fernando A; Dockrell, Hazel M

Molecular methods for distinguishing between relapse and reinfection in leprosy. (2008) Oskam, Linda; Dockrell, Hazel M; Brennan, Patrick J; Gillis, Tom; Vissa, Vara; Richardus, Jan Hendrik; IDEAL Consortium

BCG Specific and Nonspecific Effects: Different Questions, Similar Challenges. (2021) Prentice, Sarah; Dockrell, Hazel M

Post-immunization leucocytosis and its implications for the management of febrile infants. (2018) Prentice, Sarah; Kamushaaga, Zephyrian; Nash, Stephen B; Elliott, Alison M; Dockrell, Hazel M; Cose, Stephen

BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial. (2021) Prentice, Sarah; Nassanga, Beatrice; Webb, Emily L; Akello, Florence; Kiwudhu, Fred; Akurut, Hellen; Elliott, Alison M; Arts, Rob JW; Netea, Mihai G; Dockrell, Hazel M; Cose, Stephen; Delayed BCG Study Team

Correction to: Investigating the non-specific effects of BCG vaccination on the innate immune system in Ugandan neonates: study protocol for a randomised controlled trial. (2020) Prentice, Sarah; Webb, Emily L; Dockrell, Hazel M; Kaleebu, Pontiano; Elliott, Alison M; Cose, Stephen

Investigating the non-specific effects of BCG vaccination on the innate immune system in Ugandan neonates: study protocol for a randomised controlled trial. (2015) Prentice, Sarah; Webb, Emily L; Dockrell, Hazel M; Kaleebu, Pontiano; Elliott, Alison M; Cose, Stephen

Mitochondrial Signature in Human Monocytes and Resistance to Infection in C. elegans During Fumarate-Induced Innate Immune Training. (2020) Pérez-Hernández, C Angélica; Kern, Carina C; Butkeviciute, Egle; McCarthy, Elizabeth; Dockrell, Hazel M; Moreno-Altamirano, María Maximina Bertha; Aguilar-López, Bruno A; Bhosale, Gauri; Wang, Hongyuan; Gems, David; Duchen, Michael R; Smith, Steven G; Sánchez-García, Francisco Javier

Distinct serum biosignatures are associated with different tuberculosis treatment outcomes. (2019) Ronacher, Katharina; Chegou, Novel N; Kleynhans, Léanie; Djoba Siawaya, Joel F; du Plessis, Nelita; Loxton, André G; Maasdorp, Elizna; Tromp, Gerard; Kidd, Martin; Stanley, Kim; Kriel, Magdalena; Menezes, Angela; Gutschmidt, Andrea; van der Spuy, Gian D; Warren, Robin M; Dietze, Reynaldo; Okwera, Alphonse; Thiel, Bonnie; Belisle, John T; Cliff, Jacqueline M; Boom, W Henry; Johnson, John L; van Helden, Paul D; Dockrell, Hazel M; Walzl, Gerhard

Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus. (2015) Ronacher, Katharina; Joosten, Simone A; van Crevel, Reinout; Dockrell, Hazel M; Walzl, Gerhard; Ottenhoff, Tom HM

Diabetes is associated with genotypically drug-resistant tuberculosis. (2019) Ruesen, Carolien; Chaidir, Lidya; Ugarte-Gil, Cesar; van Ingen, Jakko; Critchley, Julia A; Hill, Philip C; Ruslami, Rovina; Santoso, Prayudi; Huynen, Martijn A; Dockrell, Hazel M; Moore, David AJ; Alisjahbana, Bachti; van Crevel, Reinout

Circulating B-lymphocytes as potential biomarkers of tuberculosis infection activity. (2014) Sebina, Ismail; Biraro, Irene A; Dockrell, Hazel M; Elliott, Alison M; Cose, Stephen

Long-lived memory B-cell responses following BCG vaccination. (2012) Sebina, Ismail; Cliff, Jacqueline M; Smith, Steven G; Nogaro, Sarah; Webb, Emily L; Riley, Eleanor M; Dockrell, Hazel M; Elliott, Alison M; Hafalla, Julius CR; Cose, Stephen

Decreased IFN- gamma and increased IL-4 production by human CD8(+) T cells in response to Mycobacterium tuberculosis in tuberculosis patients. (2002) Smith, SM; Klein, MR; Malin, AS; Sillah, J; McAdam, KPWJ; Dockrell, HM

Assay optimisation and technology transfer for multi-site immuno-monitoring in vaccine trials. (2017) Smith, Steven G; Harris, Stephanie A; Satti, Iman; Bryan, Donna; Walker, K Barry; Dockrell, Hazel M; McShane, Helen; Ho, Mei Mei

Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis. (2009) Smith, Steven G; Joosten, Simone A; Verscheure, Virginie; Pathan, Ansar A; McShane, Helen; Ottenhoff, Tom HM; Dockrell, Hazel M; Mascart, Françoise

Whole Blood Profiling of Bacillus Calmette-Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation. (2017) Smith, Steven G; Kleinnijenhuis, Johanneke; Netea, Mihai G; Dockrell, Hazel M

Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining. (2010) Smith, Steven G; Lalor, Maeve K; Gorak-Stolinska, Patricia; Blitz, Rose; Beveridge, Natalie ER; Worth, Andrew; McShane, Helen; Dockrell, Hazel M

Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination. (2012) Smith, Steven G; Lecher, Sophie; Blitz, Rose; Locht, Camille; Dockrell, Hazel M

Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines. (2015) Smith, Steven G; Smits, Kaatje; Joosten, Simone A; van Meijgaarden, Krista E; Satti, Iman; Fletcher, Helen A; Caccamo, Nadia; Dieli, Francesco; Mascart, Francoise; McShane, Helen; Dockrell, Hazel M; Ottenhoff, Tom HM; TBVI TB Biomarker Working Group

Polyfunctional CD4 T-cells correlate with in vitro mycobacterial growth inhibition following Mycobacterium bovis BCG-vaccination of infants. (2016) Smith, Steven G; Zelmer, Andrea; Blitz, Rose; Fletcher, Helen A; Dockrell, Hazel M

Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South Africa. (2018) Soetedjo, Nanny NM; McAllister, Susan M; Ugarte-Gil, Cesar; Firanescu, Adela G; Ronacher, Katharina; Alisjahbana, Bachti; Costache, Anca L; Zubiate, Carlos; Malherbe, Stephanus T; Koesoemadinata, Raspati C; Laurence, Yoko V; Pearson, Fiona; Kerry-Barnard, Sarah; Ruslami, Rovina; Moore, David AJ; Ioana, Mihai; Kleynhans, Leanie; Permana, Hikmat; Hill, Philip C; Mota, Maria; Walzl, Gerhard; Dockrell, Hazel M; Critchley, Julia A; van Crevel, Reinout; TANDEM Consortium

Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy. (2005) Spencer, John S; Dockrell, Hazel M; Kim, Hee Jin; Marques, Maria AM; Williams, Diana L; Martins, Marcia VSB; Martins, Marcio LF; Lima, Monica CBS; Sarno, Euzenir N; Pereira, Geraldo MB; Matos, Haroldo; Fonseca, Leila S; Sampaio, Elisabeth P; Ottenhoff, Thomas HM; Geluk, Annemieke; Cho, Sang-Nae; Stoker, Neil G; Cole, Stewart T; Brennan, Patrick J; Pessolani, Maria CV

Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy. (2012) Spencer, John S; Duthie, Malcolm S; Geluk, Annemieke; Balagon, Marivic F; Kim, Hee Jin; Wheat, William H; Chatterjee, Delphi; Jackson, Mary; Li, Wei; Kurihara, Jade N; Maghanoy, Armi; Mallari, Irene; Saunderson, Paul; Brennan, Patrick J; Dockrell, Hazel M

The use of proteomics and bioinformatics to identify novel antigens of Mycobacterium leprae towards the development of a rapid diagnostic test for the early detection of leprosy. (2008) Spencer, John S; Kim, Hee Jin; Roa, Rocio Lopez; Marques, Maria AM; da Silva Filho, Renato; Groathouse, Nathan A; Williams, Diana L; Ottenhoff, Thomas HM; Geluk, Annemieke; Cho, Sang-Nae; Gelber, Robert; Dockrell, Hazel M; Cole, Stewart T; Britton, Warwick J; Duthie, Malcolm S; Ireton, Greg; Pessolani, Maria CV; Slayden, Richard A; Brennan, Patrick J

Analysis of antibody responses to Mycobacterium leprae phenolic glycolipid I, lipoarabinomannan, and recombinant proteins to define disease subtype-specific antigenic profiles in leprosy. (2010) Spencer, John S; Kim, Hee Jin; Wheat, William H; Chatterjee, Delphi; Balagon, Marivic V; Cellona, Roland V; Tan, Esterlina V; Gelber, Robert; Saunderson, Paul; Duthie, Malcolm S; Reece, Stephen T; Burman, William; Belknap, Robert; Mac Kenzie, William R; Geluk, Annemieke; Oskam, Linda; Dockrell, Hazel M; Brennan, Patrick J; IDEAL Consortium

Four-gene Pan-African Blood Signature Predicts Progression to Tuberculosis. (2018) Suliman, S; Thompson, E; Sutherland, J; Weiner Rd, J; Ota, MOC; Shankar, S; Penn-Nicholson, A; Thiel, B; Erasmus, M; Maertzdorf, J; Duffy, FJ; Hill, PC; Hughes, EJ; Stanley, K; Downing, K; Fisher, ML; Valvo, J; Parida, SK; van der Spuy, G; Tromp, G; Adetifa, IMO; Donkor, S; Howe, R; Mayanja-Kizza, H; Boom, WH; Dockrell, H; Ottenhoff, THM; Hatherill, M; Aderem, A; Hanekom, WA; Scriba, TJ; Kaufmann, SH; Zak, DE; Walzl, G; and the GC6-74 and ACS cohort study groups

Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity. (2013) Sutherland, JS; Loxton, AG; Haks, MC; Kassa, D; Ambrose, L; Lee, J-S; Ran, L; van Baarle, D; Maertzdorf, J; Howe, R; Mayanja-Kizza, H; Boom, WH; Thiel, BA; Crampin, AC; Hanekom, W; Ota, MOC; Dockrell, H; Walzl, G; Kaufmann, SHE; Ottenhoff, THM; GCGH Biomarkers for TB consortium

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. (2013) Sutherland, Jayne S; Lalor, Maeve K; Black, Gillian F; Ambrose, Lyn R; Loxton, Andre G; Chegou, Novel N; Kassa, Desta; Mihret, Adane; Howe, Rawleigh; Mayanja-Kizza, Harriet; Gomez, Marie P; Donkor, Simon; Franken, Kees; Hanekom, Willem; Klein, Michel R; Parida, Shreemanta K; Boom, W Henry; Thiel, Bonnie A; Crampin, Amelia C; Ota, Martin; Walzl, Gerhard; Ottenhoff, Tom HM; Dockrell, Hazel M; Kaufmann, Stefan HE; GCGH Biomarkers for TB consortium

Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results. (2021) Sutherland, Jayne S; van der Spuy, Gian; Gindeh, Awa; Thuong, Nguyen Thuy Thuong; Namuganga, AnnRitah; Owolabi, Olumuyiwa; Mayanja-Kizza, Harriet; Nsereko, Mary; Thwaites, Guy; Winter, Jill; Dockrell, Hazel M; Scriba, Thomas J; Geluk, Annemieke; Corstjens, Paul; Stanley, Kim; Richardson, Tracy; Shaw, Jane A; Smith, Bronwyn; Malherbe, Stephanus T; Walzl, Gerhard; TrENDx-TB Consortium

Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells. (2019) Tanner, Rachel; Smith, Steven G; van Meijgaarden, Krista E; Giannoni, Federico; Wilkie, Morven; Gabriele, Lucia; Palma, Carla; Dockrell, Hazel M; Ottenhoff, Tom HM; McShane, Helen

Differential transcriptomic and metabolic profiles of M. africanum- and M. tuberculosis-infected patients after, but not before, drug treatment. (2015) Tientcheu, LD; Maertzdorf, J; Weiner, J; Adetifa, IM; Mollenkopf, H-J; Sutherland, JS; Donkor, S; Kampmann, B; Kaufmann, SHE; Dockrell, HM; Ota, MO

Association of slow recovery of Mycobacterium africanum-infected patients posttreatment with high content of Persister-Like bacilli in pretreatment sputum. (2016) Tientcheu, Leopold D; Bell, Andrew; Secka, Oumie; Ayorinde, Abigail; Otu, Jacob; Garton, Nathalie J; Sutherland, Jayne S; Ota, Martin O; Antonio, Martin; Dockrell, HM; Kampmann, Beate; Barer, Michael R

Host Immune Responses Differ between M. africanum- and M. tuberculosis-Infected Patients following Standard Anti-tuberculosis Treatment. (2016) Tientcheu, Leopold D; Haks, Mariëlle C; Agbla, Schadrac C; Sutherland, Jayne S; Adetifa, Ifedayo M; Donkor, Simon; Quinten, Edwin; Daramy, Mohammed; Antonio, Martin; Kampmann, Beate; Ottenhoff, Tom HM; Dockrell, Hazel M; Ota, Martin O

Differences in T-cell responses between Mycobacterium tuberculosis and Mycobacterium africanum-infected patients. (2014) Tientcheu, Leopold D; Sutherland, Jayne S; de Jong, Bouke C; Kampmann, Beate; Jafali, James; Adetifa, Ifedayo M; Antonio, Martin; Dockrell, Hazel M; Ota, Martin O

Mycobacterium tuberculosis-specific CD4(+) T-cell response is increased, and Treg cells decreased, in anthelmintic-treated patients with latent TB. (2016) Toulza, F; Tsang, L; Ottenhoff, TH; Brown, M; Dockrell, HM

Diabetes Mellitus Among Pulmonary Tuberculosis Patients From 4 Tuberculosis-endemic Countries: The TANDEM Study. (2019) Ugarte-Gil, Cesar; Alisjahbana, Bachti; Ronacher, Katharina; Riza, Anca Lelia; Koesoemadinata, Raspati C; Malherbe, Stephanus T; Cioboata, Ramona; Llontop, Juan Carlos; Kleynhans, Leanie; Lopez, Sonia; Santoso, Prayudi; Marius, Ciontea; Villaizan, Katerine; Ruslami, Rovina; Walzl, Gerhard; Panduru, Nicolae Mircea; Dockrell, Hazel M; Hill, Philip C; Mc Allister, Susan; Pearson, Fiona; Moore, David AJ; Critchley, Julia A; van Crevel, Reinout

Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers. (2020) Vickers, Molly A; Darboe, Fatoumatta; Muefong, Caleb N; Mbayo, Georgetta; Barry, Amadou; Gindeh, Awa; Njie, Sainabou; Riley, Abi-Janet; Sarr, Binta; Sambou, Basil; Dockrell, Hazel M; Charalambous, Salome; Rachow, Andrea; Owolabi, Olumuyiwa; Jayasooriya, Shamanthi; Sutherland, Jayne S

Reply to davies et Al. (2007) Walzl, G; Mistry, R; Dockrell, HM; Helden, PD; Cliff, JM

Reply to Davies et al. (2007) Walzl, Gerhard; Mistry, Rohit; Dockrell, Hazel M; Helden, Paul D van; Cliff, Jacqueline M

Biomarkers for TB treatment response: challenges and future strategies. (2008) Walzl, Gerhard; Ronacher, Katharina; Djoba Siawaya, Joel Fleury; Dockrell, Hazel M

Metabolite changes in blood predict the onset of tuberculosis. (2018) Weiner, January; Maertzdorf, Jeroen; Sutherland, Jayne S; Duffy, Fergal J; Thompson, Ethan; Suliman, Sara; McEwen, Gayle; Thiel, Bonnie; Parida, Shreemanta K; Zyla, Joanna; Hanekom, Willem A; Mohney, Robert P; Boom, W Henry; Mayanja-Kizza, Harriet; Howe, Rawleigh; Dockrell, Hazel M; Ottenhoff, Tom HM; Scriba, Thomas J; Zak, Daniel E; Walzl, Gerhard; Kaufmann, Stefan HE; GC6-74 consortium

The influence of prior exposure to environmental mycobacteria on the IFN-(gamma) response to BCG vaccination in southern England and northern Malaw. (2006) Weir, R; Black, G; Nazareth, B; Floyd, S; Stenson, S; Stanley, C; Branson, K; Sichali, L; Chaguluka, S; Donovan, L; Crampin, A; Fine, P; Dockrell, HM

The influence of previous exposure to environmental mycobacteria on the interferon-gamma response to bacille Calmette-Guérin vaccination in southern England and northern Malawi. (2006) Weir, RE; Black, GF; Nazareth, B; Floyd, S; Stenson, S; Stanley, C; Branson, K; Sichali, L; Chaguluka, SD; Donovan, L; Crampin, AC; Fine, PEM; Dockrell, HM

Interferon-gamma and skin test responses of schoolchildren in southeast England to purified protein derivatives from Mycobacterium tuberculosis and other species of mycobacteria. (2003) Weir, RE; Fine, PEM; Nazareth, B; Floyd, S; Black, GF; King, E; Stanley, C; Bliss, L; Branson, K; Dockrell, HM

Mycobacterial purified protein derivatives stimulate innate immunity: Malawians show enhanced tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses compared to those of adolescents in the United Kingdom. (2004) Weir, Rosemary E; Black, Gillian F; Dockrell, Hazel M; Floyd, Sian; Fine, Paul EM; Chaguluka, Steven D; Stenson, Sally; King, Elizabeth; Nazareth, Bernadette; Warndorff, David K; Ngwira, Bagrey; Crampin, Amelia C; Mwaungulu, Lorren; Sichali, Lifted; Jarman, Elizabeth; Donovan, Linda; Blackwell, Jenefer M

Comparison of IFN-gamma responses to mycobacterial antigens as markers of response to BCG vaccination. (2008) Weir, Rosemary E; Fine, Paul EM; Floyd, Sian; Stenson, Sally; Stanley, Carolynne; Branson, Keith; Britton, Warwick J; Huygen, Kris; Singh, Mahavir; Black, Gillian; Dockrell, Hazel M

Persistence of the immune response induced by BCG vaccination. (2008) Weir, Rosemary E; Gorak-Stolinska, Patricia; Floyd, Sian; Lalor, Maeve K; Stenson, Sally; Branson, Keith; Blitz, Rose; Ben-Smith, Anne; Fine, Paul EM; Dockrell, Hazel M picture_as_pdf

A blood RNA signature for tuberculosis disease risk: a prospective cohort study. (2016) Zak, Daniel E; Penn-Nicholson, Adam; Scriba, Thomas J; Thompson, Ethan; Suliman, Sara; Amon, Lynn M; Mahomed, Hassan; Erasmus, Mzwandile; Whatney, Wendy; Hussey, Gregory D; Abrahams, Deborah; Kafaar, Fazlin; Hawkridge, Tony; Verver, Suzanne; Hughes, E Jane; Ota, Martin; Sutherland, Jayne; Howe, Rawleigh; Dockrell, Hazel M; Boom, W Henry; Thiel, Bonnie; Ottenhoff, Tom HM; Mayanja-Kizza, Harriet; Crampin, Amelia C; Downing, Katrina; Hatherill, Mark; Valvo, Joe; Shankar, Smitha; Parida, Shreemanta K; Kaufmann, Stefan HE; Walzl, Gerhard; Aderem, Alan; Hanekom, Willem A; ACS and GC6-74 cohort study groups

Tuberculosis vaccines: Opportunities and challenges. (2018) Zhu, Bingdong; Dockrell, Hazel M; Ottenhoff, Tom HM; Evans, Thomas G; Zhang, Ying

TANDEM: understanding diabetes and tuberculosis. (2014) van Crevel, Reinout; Dockrell, Hazel M; TANDEM Consortium

Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment. (2022) van Doorn, Cassandra LR; Eckold, Clare; Ronacher, Katharina; Ruslami, Rovina; van Veen, Suzanne; Lee, Ji-Sook; Kumar, Vinod; Kerry-Barnard, Sarah; Malherbe, Stephanus T; Kleynhans, Léanie; Stanley, Kim; Hill, Philip C; Joosten, Simone A; van Crevel, Reinout; Wijmenga, Cisca; Critchley, Julia A; Walzl, Gerhard; Alisjahbana, Bachti; Haks, Mariëlle C; Dockrell, Hazel M; Ottenhoff, Tom HM; Vianello, Eleonora; Cliff, Jacqueline M; TANDEM Consortium

Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies. (2018) van Meijgaarden, Krista E; Khatri, Bhagwati; Smith, Steven G; Drittij, Anne MFH; de Paus, Roelof A; Goeman, Jelle J; Ho, Mei M; Dockrell, Hazel M; McShane, Helen; Joosten, Simone A; Ottenhoff, Tom HM

Book Section

T cell protective immune responses against TB. (2014) Dockrell, HM

BCG Vaccination: Epidemiology and Immunology. (2008) Dockrell, HM; Gorak-Stolinska, P; Rodrigues, LC

Conference or Workshop Item

Meeting report: 5th Global Forum on TB Vaccines, 20-23 February 2018, New Delhi India. (2018) Atmakuri, Krishnamohan; Penn-Nicholson, Adam; Tanner, Rachel; Dockrell, Hazel M

Immune responses induced by infant BCG vaccination in Malawi and the UK. (2005) Ben-Smith, A; Lalor, MK; Weir, RE; Gorak-Stolinska, P; Floyd, S; Makamo, K; Blitz, R; Mvula, H; Newport, MJ; Branson, K; Jahn, A; Crampin, AC; Fine, PE; Dockrell, HM

LIFETIME FOLLOW-UP OF MYCOBACTERIUM TUBERCULOSIS INFECTED INDIVIDUALS INCLUDING THOSE WITH SUBSEQUENT HIV INFECTION. (2011) Crampin, A; Longwe, H; Mulawa, D; Mwaungulu, L; Glynn, J; Dockrell, H; French, N; Fine, P

BCG associated upregulation of activation markers in human T cells. (2007) Gorak-Stolinska, P; Ben-Smith, A; Weir, RE; Lalor, MK; Fine, PEM; Dockrell, HM

Modulation of human immune responses during anti-tuberculosis treatment. (2010) Hassan, S; Dockrell, H; Cliff, J

Book

Mims' Medical Microbiology. (2013) Goering, RV; Dockrell, HM; Zuckerman, M; Roitt, IM; Chiodini, PL

Mims' Medical Microbiology. (2008) Goering, RV; Dockrell, HM; Zuckerman, M; Wakelin, D; Roitt, IM; Mims, C; Chiodini, PL

Medical Microbiology 3rd Edition. (2004) Mims, C; Dockrell, HM; Goring, RV; Roitt, I; Wakelin, D; Zuckerman, M

Thesis

Impact of Helminth Infection on Antimycobacterial Immune Responses in UK Migrants. (2017) Anwar, S

A Study Of Factors Underlying BCG Immunogenicity Differences Across Countries: The Influence Of DNA Methylation Patterns And Antigen Presenting Cells. (2019) Hasso-Agopsowicz, MJ

Vaccinia expression of mycobacterium tuberculosis antigen 85 and ESAT-6 secreted proteins. (1998) Malin, AS

The Impact of Maternal Infection with Mycobacterium tuberculosis on the Infant Response to BCG Immunisation. (2017) Mawa, PA

Investigating the Non-Specific Effects of BCG in Neonates. (2018) Prentice, S

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Hazel Dockrell - TB research and the effectiveness of vaccination. (2013) UNSPECIFIED

LSHTM - February 2013 podcast - Cancer survival, mosquito repellent resistance, TB vaccination. (2013) UNSPECIFIED

Global Talent Competition Promotes Public Health - 15 July 2010. (2010) UNSPECIFIED audio_file