Year Item Type Full Text

Bibliographic data only

Strain-dependent variation in Mycobacterium bovis BCG-induced human T-cell activation and gamma interferon production in vitro. (2007) Aguirre-Blanco, Ana M; Lukey, Pauline T; Cliff, Jacqueline M; Dockrell, Hazel M

Immune responses induced by infant BCG vaccination in Malawi and the UK. (2005) Ben-Smith, A; Lalor, MK; Weir, RE; Gorak-Stolinska, P; Floyd, S; Makamo, K; Blitz, R; Mvula, H; Newport, MJ; Branson, K; Jahn, A; Crampin, AC; Fine, PE; Dockrell, HM

The PPD-specific T-cell clonal response in UK and Malawian subjects following BCG vaccination: a new repertoire evolves over 12 months. (2006) Bennett, Andrea R; Gorak-Stolinska, Patricia; Ben-Smith, Anne; Floyd, Sian; de Lara, Catherine M; Weir, Rosemary E; Lalor, Maeve K; Makamo, Kandakuone; Msiska, Glyn K; Crampin, Amelia C; Fine, Paul EM; Dockrell, Hazel M; Beverley, Peter CL

A comparison of IFNgamma detection methods used in tuberculosis vaccine trials. (2008) Beveridge, Natalie ER; Fletcher, Helen A; Hughes, Jane; Pathan, Ansar A; Scriba, Thomas J; Minassian, Angela; Sander, Clare R; Whelan, Kathryn T; Dockrell, Hazel M; Hill, Adrian VS; Hanekom, Willem A; McShane, Helen

Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern Malawi. (2001) Black, GF; Dockrell, HM; Crampin, AC; Floyd, S; Weir, RE; Bliss, L; Sichali, L; Mwaungulu, L; Kanyongoloka, H; Ngwira, B; Warndorff, DK; Fine, PE

Relationship between IFN-gamma and skin test responsiveness to Mycobacterium tuberculosis PPD in healthy, non-BCG-vaccinated young adults in Northern Malawi. (2001) Black, GF; Fine PEM; Warndorff, DK; Floyd, S; Weir, RE; Blackwell, JM; Bliss, L; Sichali, L; Mwaungulu, L; Chaguluka, S; Jarman, E; Ngwira, B; Dockrell, HM

Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa. (2009) Black, Gillian F; Thiel, Bonnie A; Ota, Martin O; Parida, Shreemanta K; Adegbola, Richard; Boom, W Henry; Dockrell, Hazel M; Franken, Kees LMC; Friggen, Annemiek H; Hill, Philip C; Klein, Michel R; Lalor, Maeve K; Mayanja, Harriet; Schoolnik, Gary; Stanley, Kim; Weldingh, Karin; Kaufmann, Stefan HE; Walzl, Gerhard; Ottenhoff, Tom HM; GCGH Biomarkers for TB Consortium

Gamma interferon responses induced by a panel of recombinant and purified mycobacterial antigens in healthy, non-mycobacterium bovis BCG-vaccinated Malawian young adults. (2003) Black, Gillian F; Weir, Rosemary E; Chaguluka, Steven D; Warndorff, David; Crampin, Amelia C; Mwaungulu, Lorren; Sichali, Lifted; Floyd, Sian; Bliss, Lyn; Jarman, Elizabeth; Donovan, Linda; Andersen, Peter; Britton, Warwick; Hewinson, Glyn; Huygen, Kris; Paulsen, Jens; Singh, Mahavir; Prestidge, Ross; Fine, Paul EM; Dockrell, Hazel M

BCG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK: two randomised controlled studies. (2002) Black, Gillian F; Weir, Rosemary E; Floyd, Sian; Bliss, Lyn; Warndorff, David K; Crampin, Amelia C; Ngwira, Bagrey; Sichali, Lifted; Nazareth, Bernadette; Blackwell, Jenefer M; Branson, Keith; Chaguluka, Steven D; Donovan, Linda; Jarman, Elizabeth; King, Elizabeth; Fine, Paul EM; Dockrell, Hazel M

Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection. (2007) Cehovin, Ana; Cliff, Jacqueline M; Hill, Philip C; Brookes, Roger H; Dockrell, Hazel M

Differential gene expression identifies novel markers of CD4+ and CD8+ T cell activation following stimulation by Mycobacterium tuberculosis. (2004) Cliff, Jacqueline M; Andrade, Iryna NJ; Mistry, Rohit; Clayton, Christopher L; Lennon, Mark G; Lewis, Alan P; Duncan, Ken; Lukey, Pauline T; Dockrell, Hazel M

Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response. (2012) Cliff, Jacqueline M; Lee, Ji-Sook; Constantinou, Nicholas; Cho, Jang-Eun; Clark, Taane G; Ronacher, Katharina; King, Elizabeth C; Lukey, Pauline T; Duncan, Ken; Van Helden, Paul D; Walzl, Gerhard; Dockrell, Hazel M

LIFETIME FOLLOW-UP OF MYCOBACTERIUM TUBERCULOSIS INFECTED INDIVIDUALS INCLUDING THOSE WITH SUBSEQUENT HIV INFECTION. (2011) Crampin, A; Longwe, H; Mulawa, D; Mwaungulu, L; Glynn, J; Dockrell, H; French, N; Fine, P

Gamma interferon - Key, but not sufficient for protection against TB? (2007) Dockrell, HM

Roitt's essential immunology: book review. (2002) Dockrell, HM

Reply. (2002) Dockrell, HM; Black, GF; Weir, RE; Fine, PEM

BCG Vaccination: Epidemiology and Immunology. (2008) Dockrell, HM; Gorak-Stolinska, P; Rodrigues, LC

Presidential address: the role of research networks in tackling major challenges in international health. (2010) Dockrell, Hazel M

Towards new TB vaccines: What are the challenges? (2016) Dockrell, Hazel M

Another step down the development pipeline for the novel tuberculosis vaccine MVA-85A. (2011) Dockrell, Hazel M

Real vaccines in the real world: tuberculosis vaccines move south. (2008) Dockrell, Hazel M

A new challenge for the tuberculosis vaccine community? (2012) Dockrell, Hazel M

Variability between countries in cytokine responses to BCG vaccination: what impact might this have on protection? (2012) Dockrell, Hazel M; Smith, Steven G; Lalor, Maeve K

A courageous step down the road toward a new tuberculosis vaccine. (2009) Dockrell, Hazel M; Zhang, Ying

The immune response to Mycobacterium tuberculosis in HIV-infected and uninfected adults in Uganda: application of a whole blood cytokine assay in an epidemiological study. (2001) Elliott, AM; Hurst, TJ; Balyeku, MN; Quigley, MA; Kaleebu, P; French, N; Biryahwaho, B; Whitworth, JA; Dockrell, HM; Hayes, RJ

Cytokine responses and progression to active tuberculosis in HIV-1-infected Ugandans: a prospective study. (2004) Elliott, Alison M; Hodsdon, Wendy S; Kyosiimire, Jacqueline; Quigley, Maria A; Nakiyingi, Jessica S; Namujju, Proscovia B; Watera, Christine; French, Neil; Gilks, Charles F; Dockrell, Hazel M; Whitworth, James AG

Interferon-gamma responses to ESAT-6 in tuberculosis patients early into and after anti-tuberculosis treatment. (2005) Ferrand, RA; Bothamley, GH; Whelan, A; Dockrell, HM

Inhibition of mycobacterial growth in vitro following primary but not secondary vaccination with Mycobacterium bovis BCG. (2013) Fletcher, Helen A; Tanner, Rachel; Wallis, Robert S; Meyer, Joel; Manjaly, Zita-Rose; Harris, Stephanie; Satti, Iman; Silver, Richard F; Hoft, Dan; Kampmann, Beate; Walker, K Barry; Dockrell, Hazel M; Fruth, Uli; Barker, Lew; Brennan, Michael J; McShane, Helen

Analysis of data from individuals demonstrates high discordance between IFN-gamma assays and PPD-tuberculin skin tests used in screening for tuberculosis infection - In reply. (2002) Floyd, S; Black, GF; Dockrell, HM; Fine, PEM

New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy. (2012) Geluk, Annemieke; Bobosha, Kidist; van der Ploeg-van Schip, Jolien J; Spencer, John S; Banu, Sayera; Martins, Marcia VSB; Cho, Sang-Nae; Franken, Kees LMC; Kim, Hee Jin; Bekele, Yonas; Uddin, Mohammad KM; Hadi, Sheikh Abdul; Aseffa, Abraham; Pessolani, Maria CV; Pereira, Geraldo MB; Dockrell, Hazel M; Ottenhoff, Tom HM

From genome-based in silico predictions to ex vivo verification of leprosy diagnosis. (2009) Geluk, Annemieke; Spencer, John S; Bobosha, Kidist; Pessolani, Maria CV; Pereira, Geraldo MB; Banu, Sayera; Honoré, Nadine; Reece, Stephen T; MacDonald, Murdo; Sapkota, Bishwa Raj; Ranjit, Chaman; Franken, Kees LMC; Zewdie, Martha; Aseffa, Abraham; Hussain, Rabia; Stefani, Mariane M; Cho, Sang-Nae; Oskam, Linda; Brennan, Patrick J; Dockrell, Hazel M; IDEAL Consortium

Mims' Medical Microbiology. (2013) Goering, RV; Dockrell, HM; Zuckerman, M; Roitt, IM; Chiodini, PL

Mims' Medical Microbiology. (2008) Goering, RV; Dockrell, HM; Zuckerman, M; Wakelin, D; Roitt, IM; Mims, C; Chiodini, PL

BCG associated upregulation of activation markers in human T cells. (2007) Gorak-Stolinska, P; Ben-Smith, A; Weir, RE; Lalor, MK; Fine, PEM; Dockrell, HM

Immunogenicity of Danish-SSI 1331 BCG vaccine in the UK: comparison with Glaxo-Evans 1077 BCG vaccine. (2006) Gorak-Stolinska, Patricia; Weir, Rosemary E; Floyd, Sian; Lalor, Maeve K; Stenson, Sally; Branson, Keith; Blitz, Rose; Luke, Sarah; Nazareth, Bernadette; Ben-Smith, Anne; Fine, Paul EM; Dockrell, Hazel M

Building research capacity through international partnerships. (2009) Haines, Andy; Dockrell, Hazel

Modulation of human immune responses during anti-tuberculosis treatment. (2010) Hassan, S; Dockrell, H; Cliff, J

Cytokine profiles using whole-blood assays can discriminate between tuberculosis patients and healthy endemic controls in a BCG-vaccinated population. (2002) Hussain, Rabia; Kaleem, Arnawaz; Shahid, Firdaus; Dojki, Maqboola; Jamil, Bushra; Mehmood, Hammad; Dawood, Ghaffar; Dockrell, Hazel M

Immune profiling of leprosy and tuberculosis patients to 15-mer peptides of Mycobacterium leprae and M. tuberculosis GroES in a BCG vaccinated area: implications for development of vaccine and diagnostic reagents. (2004) Hussain, Rabia; Shahid, Firdaus; Zafar, Shahid; Dojki, Maqboola; Dockrell, Hazel M

Dynamics of cytokine generation in patients with active pulmonary tuberculosis. (2003) Jo, Eun-Kyeong; Park, Jeong-Kyu; Dockrell, Hazel M

Mycobacterial load affects adenosine deaminase 2 levels of tuberculous pleural effusion. (2015) Kim, Chang Ho; Lee, Jaehee; Lee, Jisook; Cliff, Jacqueline M; Toulza, Frederic; Smith, Steven; Yoo, Seung Soo; Lee, Shin Yup; Cha, Seung Ick; Park, Jae Yong; Dockrell, Hazel M

Health care workers who are to progress to active TB disease present a panel of T cell immune markers predicting such progression. (2004) Leandro, C; Ordway, D; Martins, MS; Viveiros, M; Pinto, L; Arroz, MJ; Ventura, FA; Dockrell, HM; Amaral, L

Evaluation of cell-mediated immune responses to two BCG vaccination regimes in young children in South Korea. (2011) Lee, Hyejon; Cho, Sang Nae; Kim, Hee Jin; Anh, Young Min; Choi, Ji Eun; Kim, Chang Hwi; Ock, Park Jae; Oh, Sung Hee; Kim, Deok Ryun; Floyd, Sian; Dockrell, Hazel M

Addressing diversity in tuberculosis using multidimensional approaches. (2018) Lerm, M; Dockrell, HM

Medical Microbiology 3rd Edition. (2004) Mims, C; Dockrell, HM; Goring, RV; Roitt, I; Wakelin, D; Zuckerman, M

Gene-expression patterns in whole blood identify subjects at risk for recurrent tuberculosis. (2007) Mistry, Rohit; Cliff, Jacqueline M; Clayton, Christopher L; Beyers, Nulda; Mohamed, Yasmin S; Wilson, Paul A; Dockrell, Hazel M; Wallace, Don M; van Helden, Paul D; Duncan, Ken; Lukey, Pauline T

Cytokine production and lymphocyte proliferation in patients with Nocardia brasiliensis actinomycetoma. (2004) Méndez-Tovar, Luis J; Mondragón-González, Rafael; Vega-López, Francisco; Dockrell, Hazel M; Hay, Roderick; López-Martínez, Rubén; Manzano-Gayosso, Patricia; Hernández-Hernández, Francisca; Padilla-Desgarennes, Carmen; Bonifaz, Alexandro

Respostas das citocinas T2 desencadeadas por Mycobacterium tuberculosis virulento now doentes com tuberculose pulmonar en estado avancado. (2001) Ordway, DJ; Arroz, MJ; Freire, MS; Dockrell, HM; Fernando, A; Ventura, FAAN

Comparacao das respostas celulares imunes induzidas por proteinas filtradas da cultura de Mycobacterium tuberculosis [Comparison of human cellular immune responses elicited by culture filtrate proteins of Mycobacterium tuberculosis]. (2001) Ordway, DJ; Silveira, H; Costa, L; Costa, S; Martins, M; Badura, R; Arroz, MJ; Dockrell, HM; Young, S; Ventura, FAAN

Increased Interleukin-4 production by CD8 and gammadelta T cells in health-care workers is associated with the subsequent development of active tuberculosis. (2004) Ordway, Diane J; Costa, Leonor; Martins, Marta; Silveira, Henrique; Amaral, Leonard; Arroz, Maria J; Ventura, Fernando A; Dockrell, Hazel M

Gamma delta T cell responses associated with the development of tuberculosis in health care workers. (2005) Ordway, Diane J; Pinto, Luisa; Costa, Leonor; Martins, Marta; Leandro, Clara; Viveiros, Miguel; Amaral, Leonard; Arroz, Maria J; Ventura, Fernando A; Dockrell, Hazel M

Molecular methods for distinguishing between relapse and reinfection in leprosy. (2008) Oskam, Linda; Dockrell, Hazel M; Brennan, Patrick J; Gillis, Tom; Vissa, Vara; Richardus, Jan Hendrik; IDEAL Consortium

Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus. (2015) Ronacher, Katharina; Joosten, Simone A; van Crevel, Reinout; Dockrell, Hazel M; Walzl, Gerhard; Ottenhoff, Tom HM

Decreased IFN- gamma and increased IL-4 production by human CD8(+) T cells in response to Mycobacterium tuberculosis in tuberculosis patients. (2002) Smith, SM; Klein, MR; Malin, AS; Sillah, J; McAdam, KPWJ; Dockrell, HM

Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination. (2012) Smith, Steven G; Lecher, Sophie; Blitz, Rose; Locht, Camille; Dockrell, Hazel M

Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy. (2005) Spencer, John S; Dockrell, Hazel M; Kim, Hee Jin; Marques, Maria AM; Williams, Diana L; Martins, Marcia VSB; Martins, Marcio LF; Lima, Monica CBS; Sarno, Euzenir N; Pereira, Geraldo MB; Matos, Haroldo; Fonseca, Leila S; Sampaio, Elisabeth P; Ottenhoff, Thomas HM; Geluk, Annemieke; Cho, Sang-Nae; Stoker, Neil G; Cole, Stewart T; Brennan, Patrick J; Pessolani, Maria CV

The use of proteomics and bioinformatics to identify novel antigens of Mycobacterium leprae towards the development of a rapid diagnostic test for the early detection of leprosy. (2008) Spencer, John S; Kim, Hee Jin; Roa, Rocio Lopez; Marques, Maria AM; da Silva Filho, Renato; Groathouse, Nathan A; Williams, Diana L; Ottenhoff, Thomas HM; Geluk, Annemieke; Cho, Sang-Nae; Gelber, Robert; Dockrell, Hazel M; Cole, Stewart T; Britton, Warwick J; Duthie, Malcolm S; Ireton, Greg; Pessolani, Maria CV; Slayden, Richard A; Brennan, Patrick J

Analysis of antibody responses to Mycobacterium leprae phenolic glycolipid I, lipoarabinomannan, and recombinant proteins to define disease subtype-specific antigenic profiles in leprosy. (2010) Spencer, John S; Kim, Hee Jin; Wheat, William H; Chatterjee, Delphi; Balagon, Marivic V; Cellona, Roland V; Tan, Esterlina V; Gelber, Robert; Saunderson, Paul; Duthie, Malcolm S; Reece, Stephen T; Burman, William; Belknap, Robert; Mac Kenzie, William R; Geluk, Annemieke; Oskam, Linda; Dockrell, Hazel M; Brennan, Patrick J; IDEAL Consortium

Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity. (2013) Sutherland, JS; Loxton, AG; Haks, MC; Kassa, D; Ambrose, L; Lee, J-S; Ran, L; van Baarle, D; Maertzdorf, J; Howe, R; Mayanja-Kizza, H; Boom, WH; Thiel, BA; Crampin, AC; Hanekom, W; Ota, MOC; Dockrell, H; Walzl, G; Kaufmann, SHE; Ottenhoff, THM; GCGH Biomarkers for TB consortium

Differences in T-cell responses between Mycobacterium tuberculosis and Mycobacterium africanum-infected patients. (2014) Tientcheu, Leopold D; Sutherland, Jayne S; de Jong, Bouke C; Kampmann, Beate; Jafali, James; Adetifa, Ifedayo M; Antonio, Martin; Dockrell, Hazel M; Ota, Martin O

Reply to davies et Al. (2007) Walzl, G; Mistry, R; Dockrell, HM; Helden, PD; Cliff, JM

Reply to Davies et al. (2007) Walzl, Gerhard; Mistry, Rohit; Dockrell, Hazel M; Helden, Paul D van; Cliff, Jacqueline M

Biomarkers for TB treatment response: challenges and future strategies. (2008) Walzl, Gerhard; Ronacher, Katharina; Djoba Siawaya, Joel Fleury; Dockrell, Hazel M

The influence of prior exposure to environmental mycobacteria on the IFN-(gamma) response to BCG vaccination in southern England and northern Malaw. (2006) Weir, R; Black, G; Nazareth, B; Floyd, S; Stenson, S; Stanley, C; Branson, K; Sichali, L; Chaguluka, S; Donovan, L; Crampin, A; Fine, P; Dockrell, HM

The influence of previous exposure to environmental mycobacteria on the interferon-gamma response to bacille Calmette-Guérin vaccination in southern England and northern Malawi. (2006) Weir, RE; Black, GF; Nazareth, B; Floyd, S; Stenson, S; Stanley, C; Branson, K; Sichali, L; Chaguluka, SD; Donovan, L; Crampin, AC; Fine, PEM; Dockrell, HM

Interferon-gamma and skin test responses of schoolchildren in southeast England to purified protein derivatives from Mycobacterium tuberculosis and other species of mycobacteria. (2003) Weir, RE; Fine, PEM; Nazareth, B; Floyd, S; Black, GF; King, E; Stanley, C; Bliss, L; Branson, K; Dockrell, HM

Comparison of IFN-gamma responses to mycobacterial antigens as markers of response to BCG vaccination. (2008) Weir, Rosemary E; Fine, Paul EM; Floyd, Sian; Stenson, Sally; Stanley, Carolynne; Branson, Keith; Britton, Warwick J; Huygen, Kris; Singh, Mahavir; Black, Gillian; Dockrell, Hazel M

Tuberculosis vaccines: Opportunities and challenges. (2018) Zhu, Bingdong; Dockrell, Hazel M; Ottenhoff, Tom HM; Evans, Thomas G; Zhang, Ying

TANDEM: understanding diabetes and tuberculosis. (2014) van Crevel, Reinout; Dockrell, Hazel M; TANDEM Consortium

Public

Hazel Dockrell - TB research and the effectiveness of vaccination. (2013) UNSPECIFIED

LSHTM - February 2013 podcast - Cancer survival, mosquito repellent resistance, TB vaccination. (2013) UNSPECIFIED

Global Talent Competition Promotes Public Health - 15 July 2010. (2010) UNSPECIFIED audio_file

Mitochondria: An Integrative Hub Coordinating Circadian Rhythms, Metabolism, the Microbiome, and Immunity. (2020) Aguilar-López, Bruno A; Moreno-Altamirano, María Maximina Bertha; Dockrell, Hazel M; Duchen, Michael R; Sánchez-García, Francisco Javier

Diagnosis of childhood tuberculosis and host RNA expression in Africa. (2014) Anderson, Suzanne T; Kaforou, Myrsini; Brent, Andrew J; Wright, Victoria J; Banwell, Claire M; Chagaluka, George; Crampin, Amelia C; Dockrell, Hazel M; French, Neil; Hamilton, Melissa S; Hibberd, Martin L; Kern, Florian; Langford, Paul R; Ling, Ling; Mlotha, Rachel; Ottenhoff, Tom HM; Pienaar, Sandy; Pillay, Vashini; Scott, J Anthony G; Twahir, Hemed; Wilkinson, Robert J; Coin, Lachlan J; Heyderman, Robert S; Levin, Michael; Eley, Brian ['material/summary:fileicon_text/html' not defined]

Impact of Helminth Infection on Antimycobacterial Immune Responses in UK Migrants. (2017) Anwar, S

Report on the first meeting of the IDEAL (Initiative for Diagnostic and Epidemiological Assays for Leprosy) consortium held at Armauer Hansen Research Institute, ALERT, Addis Ababa, Ethiopia on 24-27 October 2004. (2005) Aseffa, Abraham; Brennan, Patrick; Dockrell, Hazel; Gillis, Tom; Hussain, Rabia; Oskam, Linda; Richardus, Jan Hendrik; Ideal Consortium

Meeting report: 5th Global Forum on TB Vaccines, 20-23 February 2018, New Delhi India. (2018) Atmakuri, Krishnamohan; Penn-Nicholson, Adam; Tanner, Rachel; Dockrell, Hazel M

Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease. (2016) Awoniyi, DO; Teuchert, A; Sutherland, JS; Mayanja-Kizza, H; Howe, R; Mihret, A; Loxton, AG; Sheehama, J; Kassa, D; Crampin, AC; Dockrell, HM; Kidd, M; Rosenkrands, I; Geluk, A; Ottenhoff, TH; Corstjens, PL; Chegou, NN; Walzl, G; AE-TBC Consortium; COLLABORATORS; Walzl, G; Chegou, NN; Kriel, M; van der Spuy, G; Loxton, AG; Stanley, K; Malherbe, S; Mcanda, S; Kriel, B; Phalane, KG; Essone, P; Sutherland, JS; Owolabi, O; Sillah, A; Mendy, J; Gindeh, A; Donkor, S; Togun, T; Ota, M; Crampin, AC; Simukonda, F; Amberbir, A; Chilongo, F; Houben, R; Kassa, D; Gebrezgeabher, A; Mesfin, G; Belay, Y; Gebremichael, G; Alemayehu, Y; van der Vyver, M; Amutenya, FN; Nelongo, JN; Monye, L; Sheehama, JA; Iipinge, S; Mayanja-Kizza, H; Namuganga, AR; Muzanye, G; Nsereko, M; Peters, P; Howe, R; Mihret, A; Bekele, Y; Tessema, B; Yamuah, L; Ottenhoff, TH; Geluk, A; Franken, K; Corstjens, PL; Tjon Kon Fat, EM; de Dood, CJ; van der Ploeg-van Schip, JJ; Rosenkrands, I; Aagaard, C; Kaufmann, SH; Esterhuyse, MM; Cliff, JM; Dockrell, HM description

Differences between naive and memory T cell phenotype in Malawian and UK adolescents: a role for Cytomegalovirus? (2008) Ben-Smith, Anne; Gorak-Stolinska, Patricia; Floyd, Sian; Weir, Rosemary E; Lalor, Maeve K; Mvula, Hazzie; Crampin, Amelia C; Wallace, Diana; Beverley, Peter Cl; Fine, Paul Em; Dockrell, Hazel M picture_as_pdf

Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort. (2014) Biraro, Irene A; Egesa, Moses; Toulza, Frederic; Levin, Jonathan; Cose, Stephen; Joloba, Moses; Smith, Steven; Dockrell, Hazel M; Katamba, Achilles; Elliott, Alison M

Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study. (2015) Biraro, Irene Andia; Egesa, Moses; Kimuda, Simon; Smith, Steven G; Toulza, Frederic; Levin, Jonathan; Joloba, Moses; Katamba, Achilles; Cose, Stephen; Dockrell, Hazel M; Elliott, Alison M

The Use of Interferon Gamma Inducible Protein 10 as a Potential Biomarker in the Diagnosis of Latent Tuberculosis Infection in Uganda. (2016) Biraro, Irene Andia; Kimuda, Simon; Egesa, Moses; Cose, Stephen; Webb, Emily L; Joloba, Moses; Smith, Steven G; Elliott, Alison M; Dockrell, Hazel M; Katamba, Achilles

Human T cell responses to peptides of the Mycobacterium leprae 45-kD serine-rich antigen. (2002) Brahmbhatt, S; Hussain, R; Zafar, S; Dawood, G; Ottenhoff, THM; Drijfhout, JW; Bothamley, G; Smith, S; Lopez, FV; Dockrell, HM

Screening vaccine formulations for biological activity using fresh human whole blood. (2014) Brookes, Roger H; Hakimi, Jalil; Ha, Yukyung; Aboutorabian, Sepideh; Ausar, Salvador F; Hasija, Manvi; Smith, Steven G; Todryk, Stephen M; Dockrell, Hazel M; Rahman, Nausheen

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB. (2016) Chegou, NN; Sutherland, JS; Malherbe, S; Crampin, AC; Corstjens, PL; Geluk, A; Mayanja-Kizza, H; Loxton, AG; van der Spuy, G; Stanley, K; Kotzé, LA; van der Vyver, M; Rosenkrands, I; Kidd, M; van Helden, PD; Dockrell, HM; Ottenhoff, TH; Kaufmann, SH; Walzl, G; AE-TBC consortium; COLLABORATORS; Kriel, M; Malherbe, S; Kriel, B; Awoniyi, DO; Maasdorp, E; Owolabi, O; Sillah, A; Mendy, J; Gindeh, A; Donkor, S; Togun, T; Ota, M; Simukonda, F; Amberbir, A; Chilongo, F; Houben, R; Kassa, D; Gebrezgeabher, A; Mesfin, G; Belay, Y; Gebremichael, G; Alemayehu, Y; Amutenya, FN; Nelongo, JN; Monye, L; Sheehama, JA; Iipinge, S; Namuganga, AR; Muzanye, G; Nsereko, M; Peters, P; Howe, R; Mihret, A; Bekele, Y; Tessema, B; Yamuah, L; Ottenhoff, TH; Franken, KL; Corstjens, PL; Fat, EM; de Dood, CJ; van der Ploeg-van Schip, JJ; Aagaard, C; Kaufmann, SH; Esterhuyse, MM; Cliff, JM description

Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis. (2018) Chegou, Novel N; Sutherland, Jayne S; Namuganga, Anna-Ritah; Corstjens, Paul Lam; Geluk, Annemieke; Gebremichael, Gebremedhin; Mendy, Joseph; Malherbe, Stephanus; Stanley, Kim; van der Spuy, Gian D; Kriel, Magdalena; Loxton, Andre G; Kriel, Belinda; Simukonda, Felanji; Bekele, Yonas; Sheehama, Jacob A; Nelongo, Josefina; van der Vyver, Marieta; Gebrexabher, Atsbeha; Hailu, Habteyes; Esterhuyse, Maria M; Rosenkrands, Ida; Aagard, Claus; Kidd, Martin; Kassa, Desta; Mihret, Adane; Howe, Rawleigh; Cliff, Jacqueline M; Crampin, Amelia C; Mayanja-Kizza, Harriet; Kaufmann, Stefan HE; Dockrell, Hazel M; Ottenhoff, Tom HM; Walzl, Gerhard; AE-TBC consortium

Excessive Cytolytic Responses Predict Tuberculosis Relapse After Apparently Successful Treatment. (2015) Cliff, Jacqueline M; Cho, Jang-Eun; Lee, Ji-Sook; Ronacher, Katharina; King, Elizabeth C; van Helden, Paul; Walzl, Gerhard; Dockrell, Hazel M

Cellular Immune Function in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). (2019) Cliff, Jacqueline M; King, Elizabeth C; Lee, Ji-Sook; Sepúlveda, Nuno; Wolf, Asia-Sophia; Kingdon, Caroline; Bowman, Erinna; Dockrell, Hazel M; Nacul, Luis; Lacerda, Eliana; Riley, Eleanor M

T cell protective immune responses against TB. (2014) Dockrell, HM

Keep the faith--leprosy still needs new diagnostic tools and laboratory research. (2011) Dockrell, Hazel M

One Health--'joining the dots'. (2012) Dockrell, Hazel M ['material/summary:fileicon_text/html' not defined]

Working together toward vaccines and biomarkers in the real world. (2017) Dockrell, Hazel M

Can what have we learnt about BCG vaccination in the last 20 years help us to design a better tuberculosis vaccine? (2021) Dockrell, Hazel M; Butkeviciute, Egle

Report on the sixth meeting of the IDEAL (Initiative for Diagnostic and Epidemiological Assays for Leprosy) consortium held in Beijing, China on 23-25 August 2010. (2011) Dockrell, Hazel M; Geluk, Annemieke; Brennan, Patrick; Saunderson, Paul R; Oskam, Linda; Lockwood, Diana N; Xiaoman, Weng; Richardus, Jan Hendrik

Tuberculosis vaccines in the era of Covid-19 - what is taking us so long? (2022) Dockrell, Hazel M; McShane, Helen

Global collaborations in leprosy research--the future is connected. (2008) Dockrell, Hazel M; Oskam, Linda; Richardus, Jan Hendrik

What Have We Learnt about BCG Vaccination in the Last 20 Years? (2017) Dockrell, Hazel M; Smith, Steven G

A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts. (2018) Duffy, Fergal J; Thompson, Ethan; Downing, Katrina; Suliman, Sara; Mayanja-Kizza, Harriet; Boom, W Henry; Thiel, Bonnie; Weiner Iii, January; Kaufmann, Stefan HE; Dover, Drew; Tabb, David L; Dockrell, Hazel M; Ottenhoff, Tom HM; Tromp, Gerard; Scriba, Thomas J; Zak, Daniel E; Walzl, Gerhard; GC6-74 Consortium

Impact of Intermediate Hyperglycemia and Diabetes on Immune Dysfunction in Tuberculosis. (2021) Eckold, Clare; Kumar, Vinod; Weiner, January; Alisjahbana, Bachti; Riza, Anca-Lelia; Ronacher, Katharina; Coronel, Jorge; Kerry-Barnard, Sarah; Malherbe, Stephanus T; Kleynhans, Leanie; Stanley, Kim; Ruslami, Rovina; Ioana, Mihai; Ugarte-Gil, Cesar; Walzl, Gerhard; van Crevel, Reinout; Wijmenga, Cisca; Critchley, Julia A; Dockrell, Hazel M; Cliff, Jacqueline M; TANDEM consortium

Human biomarkers: can they help us to develop a new tuberculosis vaccine? (2016) Fletcher, Helen A; Dockrell, Hazel M

Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification. (2021) Gliddon, Harriet D; Kaforou, Myrsini; Alikian, Mary; Habgood-Coote, Dominic; Zhou, Chenxi; Oni, Tolu; Anderson, Suzanne T; Brent, Andrew J; Crampin, Amelia C; Eley, Brian; Heyderman, Robert; Kern, Florian; Langford, Paul R; Ottenhoff, Tom HM; Hibberd, Martin L; French, Neil; Wright, Victoria J; Dockrell, Hazel M; Coin, Lachlan J; Wilkinson, Robert J; Levin, Michael

Accuracy of diabetes screening methods used for people with tuberculosis, Indonesia, Peru, Romania, South Africa. (2018) Grint, Daniel; Alisjhabana, Bachti; Ugarte-Gil, Cesar; Riza, Anca-Leila; Walzl, Gerhard; Pearson, Fiona; Ruslami, Rovina; Moore, David AJ; Ioana, Mihai; McAllister, Susan; Ronacher, Katharina; Koeseomadinata, Raspati C; Kerry-Barnard, Sarah R; Coronel, Jorge; Malherbe, Stephanus T; Dockrell, Hazel M; Hill, Philip C; Van Crevel, Reinout; Critchley, Julia A; TANDEM consortium

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations. (2008) Hanekom, Willem A; Dockrell, Hazel M; Ottenhoff, Tom HM; Doherty, T Mark; Fletcher, Helen; McShane, Helen; Weichold, Frank F; Hoft, Dan F; Parida, Shreemanta K; Fruth, Uli J

CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis. (2009) Hasan, Zahra; Cliff, Jacqueline M; Dockrell, Hazel M; Jamil, Bushra; Irfan, Muhammad; Ashraf, Mussarat; Hussain, Rabia

PD-1, PD-L1 and PD-L2 Gene Expression on T-Cells and Natural Killer Cells Declines in Conjunction with a Reduction in PD-1 Protein during the Intensive Phase of Tuberculosis Treatment. (2015) Hassan, Syeda S; Akram, Muhammad; King, Elizabeth C; Dockrell, Hazel M; Cliff, Jacqueline M

Modulation of NKG2D expression in human CD8(+) T cells corresponding with tuberculosis drug cure. (2013) Hassan, Syeda S; Cho, Jang-Eun; Akram, Muhammad; Fielding, Katherine L; Dockrell, Hazel M; Cliff, Jacqueline M

A Study Of Factors Underlying BCG Immunogenicity Differences Across Countries: The Influence Of DNA Methylation Patterns And Antigen Presenting Cells. (2019) Hasso-Agopsowicz, MJ

Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination. (2018) Hasso-Agopsowicz, Mateusz; Scriba, Thomas J; Hanekom, Willem A; Dockrell, Hazel M; Smith, Steven G

The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection. (2006) Holland, Martin J; Faal, Nkoyo; Sarr, Isatou; Joof, Hassan; Laye, Mass; Cameron, Ewen; Pemberton-Pigott, Frederick; Dockrell, Hazel M; Bailey, Robin L; Mabey, David CW

Screening for Mycobacterium tuberculosis Infection Using Beijing/K Strain-Specific Peptides in a School Outbreak Cohort. (2021) Hong, Ji Young; Kim, Ahreum; Park, So Yeong; Cho, Sang-Nae; Dockrell, Hazel M; Hur, Yun-Gyoung

A Feasibility Study for Diagnosis of Latent Tuberculosis Infection Using an IGRA Point-of-Care Platform in South Korea. (2019) Hur, Yun Gyoung; Hong, Ji Young; Choi, Dong Hwan; Kim, Ahreum; Park, So Yeong; Kwon, Minsuk; Kang, Kyungjoon; Lee, Jeong Min; Dockrell, Hazel M; Lee, Yoonsuk; Joo, Hoodon; Cho, Sang Nae

Identification of immunological biomarkers which may differentiate latent tuberculosis from exposure to environmental nontuberculous mycobacteria in children. (2013) Hur, Yun-Gyoung; Crampin, Amelia C; Chisambo, Christina; Kanyika, James; Houben, Rein; Ndhlovu, Richard; Mzembe, Themba; Lalor, Maeve K; Saul, Jacky; Branson, Keith; Stanley, Carolynne; Ngwira, Bagrey; French, Neil; Ottenhoff, Tom H; Dockrell, Hazel M; Gorak-Stolinska, Patricia

Combination of cytokine responses indicative of latent TB and active TB in Malawian adults. (2013) Hur, Yun-Gyoung; Gorak-Stolinska, Patricia; Ben-Smith, Anne; Lalor, Maeve K; Chaguluka, Steven; Dacombe, Russell; Doherty, T Mark; Ottenhoff, Tom H; Dockrell, Hazel M; Crampin, Amelia C

Factors affecting immunogenicity of BCG in infants, a study in Malawi, The Gambia and the UK. (2014) Hur, Yun-Gyoung; Gorak-Stolinska, Patricia; Lalor, Maeve K; Mvula, Hazzie; Floyd, Sian; Raynes, John; Ben-Smith, Anne; Fitchett, Joseph R; Flanagan, Katie L; Burl, Sarah; Ota, Martin O; Crampin, Amelia C; Smith, Steven G; Dockrell, Hazel M

Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines and FoxP3 Expressing Treg Cells in Pulmonary TB. (2013) Jackson-Sillah, Dolly; Cliff, Jacqueline M; Mensah, Gloria Ivy; Dickson, Emmanuel; Sowah, Sandra; Tetteh, John KA; Addo, Kwasi K; Ottenhoff, Tom HM; Bothamley, Graham; Dockrell, Hazel M

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study. (2013) Kaforou, Myrsini; Wright, Victoria J; Oni, Tolu; French, Neil; Anderson, Suzanne T; Bangani, Nonzwakazi; Banwell, Claire M; Brent, Andrew J; Crampin, Amelia C; Dockrell, Hazel M; Eley, Brian; Heyderman, Robert S; Hibberd, Martin L; Kern, Florian; Langford, Paul R; Ling, Ling; Mendelson, Marc; Ottenhoff, Tom H; Zgambo, Femia; Wilkinson, Robert J; Coin, Lachlan J; Levin, Michael

Isolation and Potential for Transmission of Mycobacterium bovis at Human-livestock-wildlife Interface of the Serengeti Ecosystem, Northern Tanzania. (2015) Katale, BZ; Mbugi, EV; Siame, KK; Keyyu, JD; Kendall, S; Kazwala, RR; Dockrell, HM; Fyumagwa, RD; Michel, AL; Rweyemamu, M; Streicher, EM; Warren, RM; van Helden, P; Matee, MI ['material/summary:fileicon_application/msword' not defined]

Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania. (2020) Katale, Bugwesa Z; Mbelele, Peter M; Lema, Nsiande A; Campino, Susana; Mshana, Stephen E; Rweyemamu, Mark M; Phelan, Jody E; Keyyu, Julius D; Majigo, Mtebe; Mbugi, Erasto V; Dockrell, Hazel M; Clark, Taane G; Matee, Mecky I; Mpagama, Stellah

Species diversity of non-tuberculous mycobacteria isolated from humans, livestock and wildlife in the Serengeti ecosystem, Tanzania. (2014) Katale, Bugwesa Z; Mbugi, Erasto V; Botha, Louise; Keyyu, Julius D; Kendall, Sharon; Dockrell, Hazel M; Michel, Anita L; Kazwala, Rudovick R; Rweyemamu, Mark M; van Helden, Paul; Matee, Mecky I ['material/summary:fileicon_text/html' not defined]

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development. (2017) Kaufmann, Stefan HE; Dockrell, Hazel M; Drager, Nick; Ho, Mei Mei; McShane, Helen; Neyrolles, Olivier; Ottenhoff, Tom HM; Patel, Brij; Roordink, Danielle; Spertini, François; Stenger, Steffen; Thole, Jelle; Verreck, Frank AW; Williams, Ann; TBVAC2020 Consortium

Diagnostic Potential of a PPE Protein Derived from Mycobacterium tuberculosis Beijing/K Strain. (2020) Kim, Ahreum; Park, Kwang Joo; Kim, Young Sun; Cho, Sang Nae; Dockrell, Hazel M; Hur, Yun Gyoung

The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis. (2017) Lacerda, Eliana M; Bowman, Erinna W; Cliff, Jacqueline M; Kingdon, Caroline C; King, Elizabeth C; Lee, Ji-Sook; Clark, Taane G; Dockrell, Hazel M; Riley, Eleanor M; Curran, Hayley; Nacul, Luis

Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects. (2019) Lachmandas, Ekta; Eckold, Clare; Böhme, Julia; Koeken, Valerie ACM; Marzuki, Mardiana Binte; Blok, Bastiaan; Arts, Rob JW; Chen, Jinmiao; Teng, Karen WW; Ratter, Jacqueline; Smolders, Elise J; Van den Heuvel, Corina; Stienstra, Rinke; Dockrell, Hazel M; Newell, Evan; Netea, Mihai G; Singhal, Amit; Cliff, Jacqueline M; Van Crevel, Reinout

Population differences in immune responses to Bacille Calmette-Guérin vaccination in infancy. (2009) Lalor, Maeve K; Ben-Smith, Anne; Gorak-Stolinska, Patricia; Weir, Rosemary E; Floyd, Sian; Blitz, Rose; Mvula, Hazzie; Newport, Melanie J; Branson, Keith; McGrath, Nuala; Crampin, Amelia C; Fine, Paul EM; Dockrell, Hazel M

BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi. (2011) Lalor, Maeve K; Floyd, Sian; Gorak-Stolinska, Patricia; Ben-Smith, Anne; Weir, Rosemary E; Smith, Steven G; Newport, Melanie J; Blitz, Rose; Mvula, Hazzie; Branson, Keith; McGrath, Nuala; Crampin, Amelia C; Fine, Paul E; Dockrell, Hazel M

BCG vaccination: a role for vitamin D? (2011) Lalor, Maeve K; Floyd, Sian; Gorak-Stolinska, Patricia; Weir, Rosemary E; Blitz, Rose; Branson, Keith; Fine, Paul E; Dockrell, Hazel M

Complex cytokine profiles induced by BCG vaccination in UK infants. (2009) Lalor, Maeve K; Smith, Steven G; Floyd, Sian; Gorak-Stolinska, Patricia; Weir, Rosemary E; Blitz, Rose; Branson, Keith; Fine, Paul E; Dockrell, Hazel M

Utility of interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa. (2007) Lawn, Stephen D; Bangani, Nonzwakazi; Vogt, Monica; Bekker, Linda-Gail; Badri, Motasim; Ntobongwana, Marjorie; Dockrell, Hazel M; Wilkinson, Robert J; Wood, Robin picture_as_pdf

The Current Status of BCG Vaccination in Young Children in South Korea. (2012) Lee, Hyejon; Dockrell, Hazel M; Kim, Deok Ryun; Floyd, Sian; Oh, Sue Yeon; Lee, Jin Bum; Kim, Hee Jin

In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection. (2019) Lee, Hyejon; Kim, Jungho; Kang, Young Ae; Kim, Deok Ryun; Sim, Bora; Zelmer, Andrea; Fletcher, Helen A; Dockrell, Hazel M; Smith, Steven G; Cho, Sang-Nae

Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. (2007) Lin, May Young; Geluk, Annemieke; Smith, Steven G; Stewart, Amanda L; Friggen, Annemieke H; Franken, Kees LMC; Verduyn, Marleen JC; van Meijgaarden, Krista E; Voskuil, Martin I; Dockrell, Hazel M; Huygen, Kris; Ottenhoff, Tom HM; Klein, Michèl R

Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda. (2020) Lubyayi, Lawrence; Mawa, Patrice A; Nabakooza, Grace; Nakibuule, Marjorie; Tushabe, John Vianney; Serubanja, Joel; Aibo, Dorothy; Akurut, Hellen; Tumusiime, Josephine; Hasso-Agopsowicz, Mateusz; Kaleebu, Pontiano; Levin, Jonathan; Dockrell, Hazel M; Smith, Steven; Webb, Emily L; Elliott, Alison M; Cose, Stephen

Presence of human T-cell responses to the Mycobacterium leprae 45-kilodalton antigen reflects infection with or exposure to M. leprae. (2001) Macfarlane, A; Mondragon-Gonzalez, R; Vega-Lopez, F; Wieles, B; de Pena, J; Rodriguez, O; Suarez y de la Torre, R; de Vries, RR; Ottenhoff, TH; Dockrell, HM

Vaccinia expression of mycobacterium tuberculosis antigen 85 and ESAT-6 secreted proteins. (1998) Malin, AS

The Impact of Maternal Infection with Mycobacterium tuberculosis on the Infant Response to BCG Immunisation. (2017) Mawa, PA

Immune Responses Following BCG Immunization of Infants in Uganda and United Kingdom Are Similar for Purified Protein Derivative but Differ for Secretory Proteins of Mycobacterium tuberculosis. (2021) Mawa, Patrice A; Hasso-Agopsowicz, Mateusz; Lubyayi, Lawrence; Nabakooza, Grace; Nakibuule, Marjorie; Blitz, Rose; Dun, Li; Govind, Abha; Kaleebu, Pontiano; Webb, Emily L; Elliott, Alison M; Dockrell, Hazel M; Cose, Stephen; Smith, Steven G

The impact of maternal infection with Mycobacterium tuberculosis on the infant response to bacille Calmette-Guérin immunization. (2015) Mawa, Patrice A; Nkurunungi, Gyaviira; Egesa, Moses; Webb, Emily L; Smith, Steven G; Kizindo, Robert; Akello, Mirriam; Lule, Swaib A; Muwanga, Moses; Dockrell, Hazel M; Cose, Stephen; Elliott, Alison M

Maternal BCG scar is associated with increased infant proinflammatory immune responses. (2016) Mawa, Patrice Akusa; Webb, Emily L; Filali-Mouhim, Abdelali; Nkurunungi, Gyaviira; Sekaly, Rafick-Pierre; Lule, Swaib Abubaker; Prentice, Sarah; Nash, Stephen; Dockrell, Hazel M; Elliott, Alison M; Cose, Stephen

Genetic diversity of Mycobacterium tuberculosis isolated from tuberculosis patients in the Serengeti ecosystem in Tanzania. (2014) Mbugi, Erasto V; Katale, Bugwesa Z; Siame, Keith K; Keyyu, Julius D; Kendall, Sharon L; Dockrell, Hazel M; Streicher, Elizabeth M; Michel, Anita L; Rweyemamu, Mark M; Warren, Robin M; Matee, Mecky I; van Helden, Paul D

Mapping of Mycobacterium tuberculosis Complex Genetic Diversity Profiles in Tanzania and Other African Countries. (2016) Mbugi, Erasto V; Katale, Bugwesa Z; Streicher, Elizabeth M; Keyyu, Julius D; Kendall, Sharon L; Dockrell, Hazel M; Michel, Anita L; Rweyemamu, Mark M; Warren, Robin M; Matee, Mecky I; van Helden, Paul D; Couvin, David; Rastogi, Nalin

Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome. (2019) Melvin, A; Lacerda, E; Dockrell, HM; O'Rahilly, S; Nacul, L

Evaluation of Host Serum Protein Biomarkers of Tuberculosis in sub-Saharan Africa. (2021) Morris, Thomas C; Hoggart, Clive J; Chegou, Novel N; Kidd, Martin; Oni, Tolu; Goliath, Rene; Wilkinson, Katalin A; Dockrell, Hazel M; Sichali, Lifted; Banda, Louis; Crampin, Amelia C; French, Neil; Walzl, Gerhard; Levin, Michael; Wilkinson, Robert J; Hamilton, Melissa S

Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease. (2021) Mutavhatsindi, Hygon; van der Spuy, Gian D; Malherbe, Stephanus T; Sutherland, Jayne S; Geluk, Annemieke; Mayanja-Kizza, Harriet; Crampin, Amelia C; Kassa, Desta; Howe, Rawleigh; Mihret, Adane; Sheehama, Jacob A; Nepolo, Emmanuel; Günther, Gunar; Dockrell, Hazel M; Corstjens, Paul LAM; Stanley, Kim; Walzl, Gerhard; Chegou, Novel N; AE-TBC ScreenTB Consortia

How Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Progresses: The Natural History of ME/CFS. (2020) Nacul, Luis; O'Boyle, Shennae; Palla, Luigi; Nacul, Flavio E; Mudie, Kathleen; Kingdon, Caroline C; Cliff, Jacqueline M; Clark, Taane G; Dockrell, Hazel M; Lacerda, Eliana M

Evidence of Clinical Pathology Abnormalities in People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) from an Analytic Cross-Sectional Study. (2019) Nacul, Luis; de Barros, Barbara; Kingdon, Caroline C; Cliff, Jacqueline M; Clark, Taane G; Mudie, Kathleen; Dockrell, Hazel M; Lacerda, Eliana M

Regulatory T cells in erythema nodosum leprosum maintain anti-inflammatory function. (2022) Negera, Edessa; Bobosha, Kidist; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana NJ; Walker, Stephen L

New Insight into the Pathogenesis of Erythema Nodosum Leprosum: The Role of Activated Memory T-Cells. (2017) Negera, Edessa; Bobosha, Kidist; Walker, Stephen L; Endale, Birtukan; Howe, Rawleigh; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions. (2018) Negera, Edessa; Tilahun, Melaku; Bobosha, Kidist; Lambert, Saba M; Walker, Stephen L; Spencer, John S; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

Increased activated memory B-cells in the peripheral blood of patients with erythema nodosum leprosum reactions. (2017) Negera, Edessa; Walker, Stephen L; Bekele, Yonas; Dockrell, Hazel M; Lockwood, Diana N

The Effects of Prednisolone Treatment on Cytokine Expression in Patients with Erythema Nodosum Leprosum Reactions. (2018) Negera, Edessa; Walker, Stephen L; Bobosha, Kidist; Bekele, Yonas; Endale, Birtukan; Tarekegn, Azeb; Abebe, Markos; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

T-cell regulation in Erythema Nodosum Leprosum. (2017) Negera, Edessa; Walker, Stephen L; Bobosha, Kidist; Howe, Rawleigh; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

Clinico-pathological features of erythema nodosum leprosum: A case-control study at ALERT hospital, Ethiopia. (2017) Negera, Edessa; Walker, Stephen L; Girma, Selfu; Doni, Shimelis N; Tsegaye, Degafe; Lambert, Saba M; Idriss, Munir H; Tsegay, Yohanis; Dockrell, Hazel M; Aseffa, Abraham; Lockwood, Diana N

Complement C1q expression in Erythema nodosum leprosum. (2018) Negera, Edessa; Walker, Stephen L; Lema, Tsehaynesh; Aseffa, Abraham; Lockwood, Diana N; Dockrell, Hazel M

A Natural History of Disease Framework for Improving the Prevention, Management, and Research on Post-viral Fatigue Syndrome and Other Forms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. (2022) O'Boyle, Shennae; Nacul, Luis; Nacul, Flavio E; Mudie, Kathleen; Kingdon, Caroline C; Cliff, Jacqueline M; Clark, Taane G; Dockrell, Hazel M; Lacerda, Eliana M

[Increased IL-4 production in response to virulent Mycobacterium tuberculosis in tuberculosis patients with advanced disease]. (2005) Ordway, Diane J; Martins, Marta S; Costa, Leonor M; Freire, Mónica S; Arroz, Maria J; Dockrell, Hazel M; Ventura, Fernando A

Investigating the Non-Specific Effects of BCG in Neonates. (2018) Prentice, S

BCG Specific and Nonspecific Effects: Different Questions, Similar Challenges. (2021) Prentice, Sarah; Dockrell, Hazel M

Post-immunization leucocytosis and its implications for the management of febrile infants. (2018) Prentice, Sarah; Kamushaaga, Zephyrian; Nash, Stephen B; Elliott, Alison M; Dockrell, Hazel M; Cose, Stephen

BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial. (2021) Prentice, Sarah; Nassanga, Beatrice; Webb, Emily L; Akello, Florence; Kiwudhu, Fred; Akurut, Hellen; Elliott, Alison M; Arts, Rob JW; Netea, Mihai G; Dockrell, Hazel M; Cose, Stephen; Delayed BCG Study Team

Correction to: Investigating the non-specific effects of BCG vaccination on the innate immune system in Ugandan neonates: study protocol for a randomised controlled trial. (2020) Prentice, Sarah; Webb, Emily L; Dockrell, Hazel M; Kaleebu, Pontiano; Elliott, Alison M; Cose, Stephen

Investigating the non-specific effects of BCG vaccination on the innate immune system in Ugandan neonates: study protocol for a randomised controlled trial. (2015) Prentice, Sarah; Webb, Emily L; Dockrell, Hazel M; Kaleebu, Pontiano; Elliott, Alison M; Cose, Stephen

Mitochondrial Signature in Human Monocytes and Resistance to Infection in C. elegans During Fumarate-Induced Innate Immune Training. (2020) Pérez-Hernández, C Angélica; Kern, Carina C; Butkeviciute, Egle; McCarthy, Elizabeth; Dockrell, Hazel M; Moreno-Altamirano, María Maximina Bertha; Aguilar-López, Bruno A; Bhosale, Gauri; Wang, Hongyuan; Gems, David; Duchen, Michael R; Smith, Steven G; Sánchez-García, Francisco Javier

Distinct serum biosignatures are associated with different tuberculosis treatment outcomes. (2019) Ronacher, Katharina; Chegou, Novel N; Kleynhans, Léanie; Djoba Siawaya, Joel F; du Plessis, Nelita; Loxton, André G; Maasdorp, Elizna; Tromp, Gerard; Kidd, Martin; Stanley, Kim; Kriel, Magdalena; Menezes, Angela; Gutschmidt, Andrea; van der Spuy, Gian D; Warren, Robin M; Dietze, Reynaldo; Okwera, Alphonse; Thiel, Bonnie; Belisle, John T; Cliff, Jacqueline M; Boom, W Henry; Johnson, John L; van Helden, Paul D; Dockrell, Hazel M; Walzl, Gerhard

Diabetes is associated with genotypically drug-resistant tuberculosis. (2019) Ruesen, Carolien; Chaidir, Lidya; Ugarte-Gil, Cesar; van Ingen, Jakko; Critchley, Julia A; Hill, Philip C; Ruslami, Rovina; Santoso, Prayudi; Huynen, Martijn A; Dockrell, Hazel M; Moore, David AJ; Alisjahbana, Bachti; van Crevel, Reinout

Circulating B-lymphocytes as potential biomarkers of tuberculosis infection activity. (2014) Sebina, Ismail; Biraro, Irene A; Dockrell, Hazel M; Elliott, Alison M; Cose, Stephen

Long-lived memory B-cell responses following BCG vaccination. (2012) Sebina, Ismail; Cliff, Jacqueline M; Smith, Steven G; Nogaro, Sarah; Webb, Emily L; Riley, Eleanor M; Dockrell, Hazel M; Elliott, Alison M; Hafalla, Julius CR; Cose, Stephen

Assay optimisation and technology transfer for multi-site immuno-monitoring in vaccine trials. (2017) Smith, Steven G; Harris, Stephanie A; Satti, Iman; Bryan, Donna; Walker, K Barry; Dockrell, Hazel M; McShane, Helen; Ho, Mei Mei

Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis. (2009) Smith, Steven G; Joosten, Simone A; Verscheure, Virginie; Pathan, Ansar A; McShane, Helen; Ottenhoff, Tom HM; Dockrell, Hazel M; Mascart, Françoise

Whole Blood Profiling of Bacillus Calmette-Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation. (2017) Smith, Steven G; Kleinnijenhuis, Johanneke; Netea, Mihai G; Dockrell, Hazel M

Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining. (2010) Smith, Steven G; Lalor, Maeve K; Gorak-Stolinska, Patricia; Blitz, Rose; Beveridge, Natalie ER; Worth, Andrew; McShane, Helen; Dockrell, Hazel M

Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines. (2015) Smith, Steven G; Smits, Kaatje; Joosten, Simone A; van Meijgaarden, Krista E; Satti, Iman; Fletcher, Helen A; Caccamo, Nadia; Dieli, Francesco; Mascart, Francoise; McShane, Helen; Dockrell, Hazel M; Ottenhoff, Tom HM; TBVI TB Biomarker Working Group

Polyfunctional CD4 T-cells correlate with in vitro mycobacterial growth inhibition following Mycobacterium bovis BCG-vaccination of infants. (2016) Smith, Steven G; Zelmer, Andrea; Blitz, Rose; Fletcher, Helen A; Dockrell, Hazel M

Disease characteristics and treatment of patients with diabetes mellitus attending government health services in Indonesia, Peru, Romania and South Africa. (2018) Soetedjo, Nanny NM; McAllister, Susan M; Ugarte-Gil, Cesar; Firanescu, Adela G; Ronacher, Katharina; Alisjahbana, Bachti; Costache, Anca L; Zubiate, Carlos; Malherbe, Stephanus T; Koesoemadinata, Raspati C; Laurence, Yoko V; Pearson, Fiona; Kerry-Barnard, Sarah; Ruslami, Rovina; Moore, David AJ; Ioana, Mihai; Kleynhans, Leanie; Permana, Hikmat; Hill, Philip C; Mota, Maria; Walzl, Gerhard; Dockrell, Hazel M; Critchley, Julia A; van Crevel, Reinout; TANDEM Consortium

Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy. (2012) Spencer, John S; Duthie, Malcolm S; Geluk, Annemieke; Balagon, Marivic F; Kim, Hee Jin; Wheat, William H; Chatterjee, Delphi; Jackson, Mary; Li, Wei; Kurihara, Jade N; Maghanoy, Armi; Mallari, Irene; Saunderson, Paul; Brennan, Patrick J; Dockrell, Hazel M

Four-gene Pan-African Blood Signature Predicts Progression to Tuberculosis. (2018) Suliman, S; Thompson, E; Sutherland, J; Weiner Rd, J; Ota, MOC; Shankar, S; Penn-Nicholson, A; Thiel, B; Erasmus, M; Maertzdorf, J; Duffy, FJ; Hill, PC; Hughes, EJ; Stanley, K; Downing, K; Fisher, ML; Valvo, J; Parida, SK; van der Spuy, G; Tromp, G; Adetifa, IMO; Donkor, S; Howe, R; Mayanja-Kizza, H; Boom, WH; Dockrell, H; Ottenhoff, THM; Hatherill, M; Aderem, A; Hanekom, WA; Scriba, TJ; Kaufmann, SH; Zak, DE; Walzl, G; and the GC6-74 and ACS cohort study groups

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. (2013) Sutherland, Jayne S; Lalor, Maeve K; Black, Gillian F; Ambrose, Lyn R; Loxton, Andre G; Chegou, Novel N; Kassa, Desta; Mihret, Adane; Howe, Rawleigh; Mayanja-Kizza, Harriet; Gomez, Marie P; Donkor, Simon; Franken, Kees; Hanekom, Willem; Klein, Michel R; Parida, Shreemanta K; Boom, W Henry; Thiel, Bonnie A; Crampin, Amelia C; Ota, Martin; Walzl, Gerhard; Ottenhoff, Tom HM; Dockrell, Hazel M; Kaufmann, Stefan HE; GCGH Biomarkers for TB consortium

Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results. (2021) Sutherland, Jayne S; van der Spuy, Gian; Gindeh, Awa; Thuong, Nguyen Thuy Thuong; Namuganga, AnnRitah; Owolabi, Olumuyiwa; Mayanja-Kizza, Harriet; Nsereko, Mary; Thwaites, Guy; Winter, Jill; Dockrell, Hazel M; Scriba, Thomas J; Geluk, Annemieke; Corstjens, Paul; Stanley, Kim; Richardson, Tracy; Shaw, Jane A; Smith, Bronwyn; Malherbe, Stephanus T; Walzl, Gerhard; TrENDx-TB Consortium

Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells. (2019) Tanner, Rachel; Smith, Steven G; van Meijgaarden, Krista E; Giannoni, Federico; Wilkie, Morven; Gabriele, Lucia; Palma, Carla; Dockrell, Hazel M; Ottenhoff, Tom HM; McShane, Helen

Differential transcriptomic and metabolic profiles of M. africanum- and M. tuberculosis-infected patients after, but not before, drug treatment. (2015) Tientcheu, LD; Maertzdorf, J; Weiner, J; Adetifa, IM; Mollenkopf, H-J; Sutherland, JS; Donkor, S; Kampmann, B; Kaufmann, SHE; Dockrell, HM; Ota, MO

Association of slow recovery of Mycobacterium africanum-infected patients posttreatment with high content of Persister-Like bacilli in pretreatment sputum. (2016) Tientcheu, Leopold D; Bell, Andrew; Secka, Oumie; Ayorinde, Abigail; Otu, Jacob; Garton, Nathalie J; Sutherland, Jayne S; Ota, Martin O; Antonio, Martin; Dockrell, HM; Kampmann, Beate; Barer, Michael R

Host Immune Responses Differ between M. africanum- and M. tuberculosis-Infected Patients following Standard Anti-tuberculosis Treatment. (2016) Tientcheu, Leopold D; Haks, Mariëlle C; Agbla, Schadrac C; Sutherland, Jayne S; Adetifa, Ifedayo M; Donkor, Simon; Quinten, Edwin; Daramy, Mohammed; Antonio, Martin; Kampmann, Beate; Ottenhoff, Tom HM; Dockrell, Hazel M; Ota, Martin O

Mycobacterium tuberculosis-specific CD4(+) T-cell response is increased, and Treg cells decreased, in anthelmintic-treated patients with latent TB. (2016) Toulza, F; Tsang, L; Ottenhoff, TH; Brown, M; Dockrell, HM

Diabetes Mellitus Among Pulmonary Tuberculosis Patients From 4 Tuberculosis-endemic Countries: The TANDEM Study. (2019) Ugarte-Gil, Cesar; Alisjahbana, Bachti; Ronacher, Katharina; Riza, Anca Lelia; Koesoemadinata, Raspati C; Malherbe, Stephanus T; Cioboata, Ramona; Llontop, Juan Carlos; Kleynhans, Leanie; Lopez, Sonia; Santoso, Prayudi; Marius, Ciontea; Villaizan, Katerine; Ruslami, Rovina; Walzl, Gerhard; Panduru, Nicolae Mircea; Dockrell, Hazel M; Hill, Philip C; Mc Allister, Susan; Pearson, Fiona; Moore, David AJ; Critchley, Julia A; van Crevel, Reinout

Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers. (2020) Vickers, Molly A; Darboe, Fatoumatta; Muefong, Caleb N; Mbayo, Georgetta; Barry, Amadou; Gindeh, Awa; Njie, Sainabou; Riley, Abi-Janet; Sarr, Binta; Sambou, Basil; Dockrell, Hazel M; Charalambous, Salome; Rachow, Andrea; Owolabi, Olumuyiwa; Jayasooriya, Shamanthi; Sutherland, Jayne S

Metabolite changes in blood predict the onset of tuberculosis. (2018) Weiner, January; Maertzdorf, Jeroen; Sutherland, Jayne S; Duffy, Fergal J; Thompson, Ethan; Suliman, Sara; McEwen, Gayle; Thiel, Bonnie; Parida, Shreemanta K; Zyla, Joanna; Hanekom, Willem A; Mohney, Robert P; Boom, W Henry; Mayanja-Kizza, Harriet; Howe, Rawleigh; Dockrell, Hazel M; Ottenhoff, Tom HM; Scriba, Thomas J; Zak, Daniel E; Walzl, Gerhard; Kaufmann, Stefan HE; GC6-74 consortium

Mycobacterial purified protein derivatives stimulate innate immunity: Malawians show enhanced tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses compared to those of adolescents in the United Kingdom. (2004) Weir, Rosemary E; Black, Gillian F; Dockrell, Hazel M; Floyd, Sian; Fine, Paul EM; Chaguluka, Steven D; Stenson, Sally; King, Elizabeth; Nazareth, Bernadette; Warndorff, David K; Ngwira, Bagrey; Crampin, Amelia C; Mwaungulu, Lorren; Sichali, Lifted; Jarman, Elizabeth; Donovan, Linda; Blackwell, Jenefer M

Persistence of the immune response induced by BCG vaccination. (2008) Weir, Rosemary E; Gorak-Stolinska, Patricia; Floyd, Sian; Lalor, Maeve K; Stenson, Sally; Branson, Keith; Blitz, Rose; Ben-Smith, Anne; Fine, Paul EM; Dockrell, Hazel M picture_as_pdf

A blood RNA signature for tuberculosis disease risk: a prospective cohort study. (2016) Zak, Daniel E; Penn-Nicholson, Adam; Scriba, Thomas J; Thompson, Ethan; Suliman, Sara; Amon, Lynn M; Mahomed, Hassan; Erasmus, Mzwandile; Whatney, Wendy; Hussey, Gregory D; Abrahams, Deborah; Kafaar, Fazlin; Hawkridge, Tony; Verver, Suzanne; Hughes, E Jane; Ota, Martin; Sutherland, Jayne; Howe, Rawleigh; Dockrell, Hazel M; Boom, W Henry; Thiel, Bonnie; Ottenhoff, Tom HM; Mayanja-Kizza, Harriet; Crampin, Amelia C; Downing, Katrina; Hatherill, Mark; Valvo, Joe; Shankar, Smitha; Parida, Shreemanta K; Kaufmann, Stefan HE; Walzl, Gerhard; Aderem, Alan; Hanekom, Willem A; ACS and GC6-74 cohort study groups

Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment. (2022) van Doorn, Cassandra LR; Eckold, Clare; Ronacher, Katharina; Ruslami, Rovina; van Veen, Suzanne; Lee, Ji-Sook; Kumar, Vinod; Kerry-Barnard, Sarah; Malherbe, Stephanus T; Kleynhans, Léanie; Stanley, Kim; Hill, Philip C; Joosten, Simone A; van Crevel, Reinout; Wijmenga, Cisca; Critchley, Julia A; Walzl, Gerhard; Alisjahbana, Bachti; Haks, Mariëlle C; Dockrell, Hazel M; Ottenhoff, Tom HM; Vianello, Eleonora; Cliff, Jacqueline M; TANDEM Consortium

Cross-laboratory evaluation of multiplex bead assays including independent common reference standards for immunological monitoring of observational and interventional human studies. (2018) van Meijgaarden, Krista E; Khatri, Bhagwati; Smith, Steven G; Drittij, Anne MFH; de Paus, Roelof A; Goeman, Jelle J; Ho, Mei M; Dockrell, Hazel M; McShane, Helen; Joosten, Simone A; Ottenhoff, Tom HM