Outcomes in HIV-infected patients who develop tuberculosis after starting antiretroviral treatment in Malawi.

JK-L Yu; C-N Bong; SC-C Chen; R Dzimadzi; D-Y Lu; SD Makombe; EJ Schouten; K Kamoto; AD Harries; (2008) Outcomes in HIV-infected patients who develop tuberculosis after starting antiretroviral treatment in Malawi. The international journal of tuberculosis and lung disease, 12 (6). pp. 692-694. ISSN 1027-3719 https://material-uat.leaf.cosector.com/id/eprint/7307
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A retrospective review was conducted of patients starting antiretroviral treatment (ART) at Mzuzu Central Hospital, Malawi, to identify those who developed tuberculosis (TB) within 6 months of commencing ART and document their treatment outcomes. Of 2933 patients, 22 (0.75%) developed active TB, 17 (77%) of whom had commenced ART as a result of unexplained weight loss and/or fever. Of those who developed TB, 41% successfully completed anti-tuberculosis treatment, with lower survival probabilities than patients who did not develop TB. Easier methods are needed to diagnose TB in human immunodeficiency virus-infected patients and to prevent patients from developing TB while on ART.

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