Are large trials less reliable than small trials?

Gerta Rücker; Guido Schwarzer; Martin Schumacher; James Carpenter ; (2009) Are large trials less reliable than small trials? Journal of clinical epidemiology, 62 (8). pp. 886-887. ISSN 0895-4356 DOI: 10.1016/j.jclinepi.2009.03.007