DNA breaks as triggers for antigenic variation in African trypanosomes.

Sam Alsford ORCID logo; David Horn; Lucy Glover; (2009) DNA breaks as triggers for antigenic variation in African trypanosomes. Genome biology, 10 (6). 223-. ISSN 1465-6906 DOI: 10.1186/gb-2009-10-6-223
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The DNA repair machinery has been co-opted for antigenic variation in African trypanosomes. New work directly demonstrates that a double-strand break initiates a switch in the expressed variant surface coat.


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