winratiotest: A command for implementing the win ratio and stratified win ratio in Stata

The win ratio is a statistical method most commonly used for analyzing composite outcomes in clinical trials. Composite outcomes are composed of two or more distinct ‘component’ events (e.g. myocardial infarction, death) and are typically analyzed using time-to-first event methods ignoring the relative importance of the component events. When using the win ratio, component events are instead placed into a hierarchy from most to least important, more important components can then be prioritized over less important outcomes (e.g., death, followed by myocardial infarction). Furthermore, the win ratio enables outcomes of different types (e.g., timeto-event, continuous, binary, ordinal, and repeat events) to be combined. We present winratiotest, a program to implement the win ratio approach for hierarchical outcomes in a flexible and user-friendly way.