Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States.

Estee Y Cramer ORCID logo; Evan L Ray ORCID logo; Velma K Lopez ORCID logo; Johannes Bracher ORCID logo; Andrea Brennen; Alvaro J Castro Rivadeneira; Aaron Gerding; Tilmann Gneiting ORCID logo; Katie H House; Yuxin Huang; +285 more... 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Pinar Keskinocak ORCID logo; John Asplund; Arden Baxter ORCID logo; Buse Eylul Oruc ORCID logo; Nicoleta Serban; Sercan O Arik; Mike Dusenberry; Arkady Epshteyn; Elli Kanal; Long T Le; Chun-Liang Li; Tomas Pfister; Dario Sava; Rajarishi Sinha ORCID logo; Thomas Tsai; Nate Yoder ORCID logo; Jinsung Yoon; Leyou Zhang ORCID logo; Sam Abbott; Nikos I Bosse; Sebastian Funk ORCID logo; Joel Hellewell; Sophie R Meakin ORCID logo; Katharine Sherratt ORCID logo; Mingyuan Zhou; Rahi Kalantari; Teresa K Yamana ORCID logo; Sen Pei ORCID logo; Jeffrey Shaman ORCID logo; Michael L Li ORCID logo; Dimitris Bertsimas ORCID logo; Omar Skali Lami ORCID logo; Saksham Soni ORCID logo; Hamza Tazi Bouardi ORCID logo; Turgay Ayer; Madeline Adee; Jagpreet Chhatwal; Ozden O Dalgic; Mary A Ladd; Benjamin P Linas; Peter Mueller; Jade Xiao; Yuanjia Wang ORCID logo; Qinxia Wang; Shanghong Xie; Donglin Zeng; Alden Green; Jacob Bien; Logan Brooks; Addison J Hu; Maria Jahja; Daniel McDonald ORCID logo; Balasubramanian Narasimhan; Collin Politsch ORCID logo; Samyak Rajanala ORCID logo; Aaron Rumack ORCID logo; Noah Simon; Ryan J Tibshirani ORCID logo; Rob Tibshirani; Valerie Ventura; Larry Wasserman; Eamon B O'Dea; John M Drake ORCID logo; Robert Pagano; Quoc T Tran; Lam Si Tung Ho ORCID logo; Huong Huynh; Jo W Walker; Rachel B Slayton ORCID logo; Michael A Johansson ORCID logo; Matthew Biggerstaff ORCID logo; Nicholas G Reich ORCID logo; (2022) Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States. Proceedings of the National Academy of Sciences, 119 (15). e2113561119-. ISSN 0027-8424 DOI: 10.1073/pnas.2113561119
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Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. Starting in April 2020, the US COVID-19 Forecast Hub (https://covid19forecasthub.org/) collected, disseminated, and synthesized tens of millions of specific predictions from more than 90 different academic, industry, and independent research groups. A multimodel ensemble forecast that combined predictions from dozens of groups every week provided the most consistently accurate probabilistic forecasts of incident deaths due to COVID-19 at the state and national level from April 2020 through October 2021. The performance of 27 individual models that submitted complete forecasts of COVID-19 deaths consistently throughout this year showed high variability in forecast skill across time, geospatial units, and forecast horizons. Two-thirds of the models evaluated showed better accuracy than a naïve baseline model. Forecast accuracy degraded as models made predictions further into the future, with probabilistic error at a 20-wk horizon three to five times larger than when predicting at a 1-wk horizon. This project underscores the role that collaboration and active coordination between governmental public-health agencies, academic modeling teams, and industry partners can play in developing modern modeling capabilities to support local, state, and federal response to outbreaks.


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