Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February.
Daniel J Grint ;
Kevin Wing ;
Elizabeth Williamson ;
Helen I McDonald ;
Krishnan Bhaskaran ;
DavidEvans;
Stephen Jw Evans ;
Alex JWalker;
GeorgeHickman;
Emily Nightingale ;
+26 more...
Anna Schultze ;
Christopher T Rentsch ;
ChrisBates;
JonathanCockburn;
Helen JCurtis;
Caroline EMorton;
SebastianBacon;
SimonDavy;
Angel Ys Wong ;
AmirMehrkar;
Laurie Tomlinson ;
Ian J Douglas ;
Rohini Mathur ;
PaulaBlomquist;
BrianMacKenna;
PeterIngelsby;
RichardCroker;
JohnParry;
FrankHester;
SamHarper;
Nicholas JDeVito;
WillHulme;
John Tazare ;
Ben Goldacre ;
Liam Smeeth ;
Rosalind M Eggo ;
(2021)
Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February.
Eurosurveillance, 26 (11).
pp. 10-15.
ISSN 1025-7917
DOI: 10.2807/1560-7917.ES.2021.26.11.2100256
The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is critical for pandemic planning. We found increased risk of death for VOC compared with non-VOC cases in England (hazard ratio: 1.67; 95% confidence interval: 1.34-2.09; p < 0.0001). Absolute risk of death by 28 days increased with age and comorbidities. This VOC has potential to spread faster with higher mortality than the pandemic to date.
Item Type | Article |
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Elements ID | 158158 |
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Read more research from the creator(s):
- Grint, Daniel
- Wing, K
- Williamson, E
- McDonald, Helen
- Bhaskaran, K
- Evans, S
- Nightingale, Emily S
- Schultze, Anna
- Rentsch, Christopher
- Wong, Angel YS
- Tomlinson, Laurie A
- Douglas, I
- Mathur, Rohini
- Tazare, John
- Goldacre, Ben
- Smeeth, L
- Eggo, RM
Find work associated with the faculties and division(s):
- Dept of Infectious Disease Epidemiology
- Dept of Non-Communicable Disease Epidemiology
- Dept of Medical Statistics
- Directorate
Find work associated with the research centre(s):
- Covid-19 Research
- EHR Research Group
- Centre for the Mathematical Modelling of Infectious Diseases
- ?? 181801 ??
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