Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.
Sona Jabang ;
Annette Erhart ;
Saffiatou Darboe ;
Aru-Kumba Baldeh;
Valerie Delforge;
Gabriella Watson;
Ebenezer Foster-Nyarko ;
Rasheed Salaudeen;
Bolarinde Lawal ;
Grant Mackenzie ;
+4 more...
Anne Botteaux;
Martin Antonio ;
Pierre R Smeesters;
On Behalf Of The Mrcg StrepA Study Group;
(2021)
Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.
Vaccines, 9 (2).
p. 124.
DOI: 10.3390/vaccines9020124
Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.
ORCID: https://orcid.org/0000-0002-7596-706X
ORCID: https://orcid.org/0000-0002-0522-4965
ORCID: https://orcid.org/0000-0002-4711-3307
ORCID: https://orcid.org/0000-0001-6620-9403
ORCID: https://orcid.org/0000-0003-4822-6597
ORCID: https://orcid.org/0000-0002-4994-2627
ORCID: https://orcid.org/0000-0002-4810-1308