Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis.
Sam Alsford 
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(2014)
Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis.
Microbial cell (Graz, Austria), 1 (8).
pp. 270-272.
ISSN 2311-2638
DOI: 10.15698/mic2014.08.162
;
(2014)
Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis.
Microbial cell (Graz, Austria), 1 (8).
pp. 270-272.
ISSN 2311-2638
DOI: 10.15698/mic2014.08.162
Most African trypanosomes, including the veterinary species Trypanosoma brucei brucei and T. congolense are susceptible to lysis by human serum. A recent study by Alsford et al. [PLoS Pathogens (2014) 10, e1004130] has identified a T. b. brucei lysosomal cathepsin with an inhibitory effect on human serum's trypanolytic action.
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picture_as_pdf - 2014 CATL & HS sensitivity - commentary - Micro Cell.pdf
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