Evaluation of the efficacy of carbosulfan and permethrin-impregnated curtains against Anopheles gambiae in a village in Burkina Faso, West Africa: Society Meeting at Manson House, London, 7 December 2000: Research in progress: short presentation

Pyrethroid resistance is a serious threat to the continued success of impregnated bednets and has been reported in the main malaria vector Anopheles gambiae s.s. in several West African countries (CHANDRE, F. 77, 230-234). In Ivory Coast, KOLACZINSKI, J. et al.) 2000: Bulletin of Entomological Research, 90, 125-132) showed that a carbosulfan-impregnated bednet performed significantly better than pyrethroid-impgregnated bednets. Because of concerns about possible toxicity, carbosulfan treatment of curtains may be preferable and such curtains were compared with permethrin-treated curtains for preventing house entry by mosquitoes, as measured by indoor light traps. The trial was carried out in a village near Ouagadougou, Burkina Faso in the wet season of 2000. Fifteen houses were provided with curtains (carbosulfan 0.2 g/m?, permethrin 1 g/m? or untreated). Five houses without curtains were used as controls. In about 60 trap-nights per treatment 1269-4437 An. gambia s.l. were caught. The percentage reduction in geometric mean count, compared with no nets, was 48.8% for untreated nets (P = 0.015), 64.2% for permethrin (P < 0.001) and 84.4% for carbosulfan (P <0.001). Regression analyses showed that permethrin did not perform significantly better than untreated curtains (P=0.141) whereas carbosulfan did perform significantly better than untreated and permtherin-treated curtains (P < 0.001)