Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples.
Stephen RC Howie;
Gerard AJ Morris;
Rafal Tokarz;
Bernard E Ebruke;
Eunice M Machuka;
Readon C Ideh;
Osaretin Chimah;
Ousman Secka;
John Townend;
Michel Dione;
+11 more...
Claire Oluwalana;
Malick Njie;
Mariatou Jallow;
Philip C Hill;
Martin Antonio ;
Brian Greenwood ;
Thomas Briese;
Kim Mulholland ;
Tumani Corrah;
W Ian Lipkin;
Richard A Adegbola;
(2014)
Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples.
Clinical infectious diseases, 59 (5).
pp. 682-685.
ISSN 1058-4838
DOI: 10.1093/cid/ciu384
Molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcus pneumoniae, >75% being of serotypes covered by current pneumococcal conjugate vaccines. Multiple pathogens were detected frequently, notably Haemophilus influenzae (mostly nontypeable) together with S. pneumoniae.
Item Type | Article |
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ISI | 342921100017 |
Explore Further
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130311 (OA Location)
- 10.1093/cid/ciu384 (DOI)
- 24867789 (PubMed)
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ORCID: https://orcid.org/0000-0002-4810-1308
ORCID: https://orcid.org/0000-0001-5725-9118
ORCID: https://orcid.org/0000-0001-7947-680X