In vitro antiplasmodial activity of extracts of Argentinian plants.

S Debenedetti; L Muschietti; C van Baren; M Clavin; A Broussalis; V Martino; PJ Houghton; D Warhurst; J Steele; (2002) In vitro antiplasmodial activity of extracts of Argentinian plants. Journal of ethnopharmacology, 80 (2-3). pp. 163-166. ISSN 0378-8741 DOI: 10.1016/s0378-8741(02)00024-7
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Fifteen extracts from nine selected Argentine medicinal plants were tested for their antiplasmodial activity in vitro by assessing their ability to inhibit the uptake of [3H]-hypoxanthine into the Plasmodium falciparum K1 pyrimethamine/chloroquine resistant strain. The methanol extract of Satureja parvifolia showed good antiplasmodial activity (IC(50) 3 microg/ml). Inhibition of the growth of P. falciparum was also observed with aqueous extracts of Buddleja globosa and S. parvifolia.

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