Items where Research Centre is "Antimicrobial Resistance Centre (AMR)"

Research Centres (23573)

Antimicrobial Resistance Centre (AMR) (807) Month Authors/Creators Item Type Full Text

December 2014

Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains. (2014) Chugh, Monika; Scheurer, Christian; Sax, Sibylle; Bilsland, Elizabeth; van Schalkwyk, Donelly A; Wicht, Kathryn J; Hofmann, Natalie; Sharma, Anil; Bashyam, Sridevi; Singh, Shivendra; Oliver, Stephen G; Egan, Timothy J; Malhotra, Pawan; Sutherland, Colin J; Beck, Hans-Peter; Wittlin, Sergio; Spangenberg, Thomas; Ding, Xavier C

A proportion of mutations fixed in the genomes of in vitro selected isogenic drug-resistant Mycobacterium tuberculosis mutants can be detected as minority variants in the parent culture. (2014) Bergval, Indra; Coll, Francesc; Schuitema, Anja; de Ronde, Hans; Mallard, Kim; Pain, Arnab; McNerney, Ruth; Clark, Taane G; Anthony, Richard M

November 2014

Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis. (2014) Okell, Lucy C; Cairns, Matthew; Griffin, Jamie T; Ferguson, Neil M; Tarning, Joel; Jagoe, George; Hugo, Pierre; Baker, Mark; D'Alessandro, Umberto; Bousema, Teun; Ubben, David; Ghani, Azra C

Anthropometric indices of Gambian children after one or three annual rounds of mass drug administration with azithromycin for trachoma control. (2014) Burr, Sarah E; Hart, John; Edwards, Tansy; Harding-Esch, Emma M; Holland, Martin J; Mabey, David CW; Sillah, Ansumana; Bailey, Robin L

Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting. (2014) Perdigão, João; Silva, Hugo; Machado, Diana; Macedo, Rita; Maltez, Fernando; Silva, Carla; Jordao, Luisa; Couto, Isabel; Mallard, Kim; Coll, Francesc; Hill-Cawthorne, Grant A; McNerney, Ruth; Pain, Arnab; Clark, Taane G; Viveiros, Miguel; Portugal, Isabel

October 2014

A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis. (2014) Burrell-Saward, Hollie; Rodgers, Jean; Bradley, Barbara; Croft, Simon L; Ward, Theresa H

September 2014

Reappraisal of known malaria resistance loci in a large multicenter study. (2014) Malaria Genomic Epidemiology Network; Malaria Genomic Epidemiology Network

Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients. (2014) Gadalla, Nahla B; Malmberg, Maja; Adam, Ishag; Oguike, Mary C; Beshir, Khalid; Elzaki, Salah-Eldin; Mukhtar, Izdihar; Gadalla, Amal A; Warhurst, David C; Ngasala, Billy; Mårtensson, Andreas; El-Sayed, Badria B; Gil, J Pedro; Sutherland, Colin J

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. (2014) Takala-Harrison, Shannon; Jacob, Christopher G; Arze, Cesar; Cummings, Michael P; Silva, Joana C; Dondorp, Arjen M; Fukuda, Mark M; Hien, Tran Tinh; Mayxay, Mayfong; Noedl, Harald; Nosten, Francois; Kyaw, Myat P; Nhien, Nguyen Thanh Thuy; Imwong, Mallika; Bethell, Delia; Se, Youry; Lon, Chanthap; Tyner, Stuart D; Saunders, David L; Ariey, Frederic; Mercereau-Puijalon, Odile; Menard, Didier; Newton, Paul N; Khanthavong, Maniphone; Hongvanthong, Bouasy; Starzengruber, Peter; Fuehrer, Hans-Peter; Swoboda, Paul; Khan, Wasif A; Phyo, Aung Pyae; Nyunt, Myaing M; Nyunt, Myat H; Brown, Tyler S; Adams, Matthew; Pepin, Christopher S; Bailey, Jason; Tan, John C; Ferdig, Michael T; Clark, Taane G; Miotto, Olivo; MacInnis, Bronwyn; Kwiatkowski, Dominic P; White, Nicholas J; Ringwald, Pascal; Plowe, Christopher V

Absence of putative artemisinin resistance mutations among Plasmodium falciparum in Sub-Saharan Africa: a molecular epidemiologic study. (2014) Taylor, Steve M; Parobek, Christian M; DeConti, Derrick K; Kayentao, Kassoum; Coulibaly, Sheick Oumar; Greenwood, Brian M; Tagbor, Harry; Williams, John; Bojang, Kalifa; Njie, Fanta; Desai, Meghna; Kariuki, Simon; Gutman, Julie; Mathanga, Don P; Mårtensson, Andreas; Ngasala, Billy; Conrad, Melissa D; Rosenthal, Philip J; Tshefu, Antoinette K; Moormann, Ann M; Vulule, John M; Doumbo, Ogobara K; Ter Kuile, Feiko O; Meshnick, Steven R; Bailey, Jeffrey A; Juliano, Jonathan J

August 2014

Drivers and trajectories of resistance to new first-line drug regimens for tuberculosis. (2014) Shrestha, Sourya; Knight, Gwenan M; Fofana, Mariam; Cohen, Ted; White, Richard G; Cobelens, Frank; Dowdy, David W

July 2014

Introducing rapid diagnostic tests for malaria into drug shops in Uganda: design and implementation of a cluster randomized trial. (2014) Mbonye, Anthony K; Magnussen, Pascal; Chandler, Clare IR; Hansen, Kristian S; Lal, Sham; Cundill, Bonnie; Lynch, Caroline A; Clarke, Siân E

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. (2014) Venkatesan, Meera; Gadalla, Nahla B; Stepniewska, Kasia; Dahal, Prabin; Nsanzabana, Christian; Moriera, Clarissa; Price, Ric N; Mårtensson, Andreas; Rosenthal, Philip J; Dorsey, Grant; Sutherland, Colin J; Guérin, Philippe; Davis, Timothy ME; Ménard, Didier; Adam, Ishag; Ademowo, George; Arze, Cesar; Baliraine, Frederick N; Berens-Riha, Nicole; Björkman, Anders; Borrmann, Steffen; Checchi, Francesco; Desai, Meghna; Dhorda, Mehul; Djimdé, Abdoulaye A; El-Sayed, Badria B; Eshetu, Teferi; Eyase, Frederick; Falade, Catherine; Faucher, Jean-François; Fröberg, Gabrielle; Grivoyannis, Anastasia; Hamour, Sally; Houzé, Sandrine; Johnson, Jacob; Kamugisha, Erasmus; Kariuki, Simon; Kiechel, Jean-René; Kironde, Fred; Kofoed, Poul-Erik; LeBras, Jacques; Malmberg, Maja; Mwai, Leah; Ngasala, Billy; Nosten, Francois; Nsobya, Samuel L; Nzila, Alexis; Oguike, Mary; Otienoburu, Sabina Dahlström; Ogutu, Bernhards; Ouédraogo, Jean-Bosco; Piola, Patrice; Rombo, Lars; Schramm, Birgit; Somé, A Fabrice; Thwing, Julie; Ursing, Johan; Wong, Rina PM; Zeynudin, Ahmed; Zongo, Issaka; Plowe, Christopher V; Sibley, Carol Hopkins; Asaq Molecular Marker Study Group

Carriage of Staphylococcus aureus in Thika Level 5 Hospital, Kenya: a cross-sectional study. (2014) Aiken, Alexander M; Mutuku, Irene M; Sabat, Artur J; Akkerboom, Viktoria; Mwangi, Jonah; Scott, J Anthony G; Morpeth, Susan C; Friedrich, Alexander W; Grundmann, Hajo

Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania. (2014) Kavishe, Reginald A; Paulo, Petro; Kaaya, Robert D; Kalinga, Akili; van Zwetselaar, Marco; Chilongola, Jaffu; Roper, Cally; Alifrangis, Michael

Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT. (2014) Henriques, Gisela; Hallett, Rachel L; Beshir, Khalid B; Gadalla, Nahla B; Johnson, Rachel E; Burrow, Rebekah; van Schalkwyk, Donelly A; Sawa, Patrick; Omar, Sabah A; Clark, Taane G; Bousema, Teun; Sutherland, Colin J

June 2014

A population-based spatio-temporal analysis of Clostridium difficile infection in Queensland, Australia over a 10-year period. (2014) Furuya-Kanamori, Luis; Robson, Jenny; Soares Magalhães, Ricardo J; Yakob, Laith; McKenzie, Samantha J; Paterson, David L; Riley, Thomas V; Clements, Archie CA

Recombinations in staphylococcal cassette chromosome mec elements compromise the molecular detection of methicillin resistance in Staphylococcus aureus. (2014) Hill-Cawthorne, Grant A; Hudson, Lyndsey O; El Ghany, Moataz Fouad Abd; Piepenburg, Olaf; Nair, Mridul; Dodgson, Andrew; Forrest, Matthew S; Clark, Taane G; Pain, Arnab

Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates. (2014) Ocholla, Harold; Preston, Mark D; Mipando, Mwapatsa; Jensen, Anja TR; Campino, Susana; MacInnis, Bronwyn; Alcock, Daniel; Terlouw, Anja; Zongo, Issaka; Oudraogo, Jean-Bosco; Djimde, Abdoulaye A; Assefa, Samuel; Doumbo, Ogobara K; Borrmann, Steffen; Nzila, Alexis; Marsh, Kevin; Fairhurst, Rick M; Nosten, Francois; Anderson, Tim JC; Kwiatkowski, Dominic P; Craig, Alister; Clark, Taane G; Montgomery, Jacqui

Assessing control bundles for Clostridium difficile: a review and mathematical model. (2014) Yakob, Laith; Riley, Thomas V; Paterson, David L; Marquess, John; Clements, Archie Ca

May 2014

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei. (2014) Alsford, Sam; Currier, Rachel B; Guerra-Assunção, José Afonso; Clark, Taane G; Horn, David

Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target. (2014) Tewari, Rita; Patzewitz, Eva-Maria; Poulin, Benoit; Stewart, Lindsay; Baker, David A

Temporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in Uganda. (2014) Mbogo, George W; Nankoberanyi, Sheila; Tukwasibwe, Stephen; Baliraine, Frederick N; Nsobya, Samuel L; Conrad, Melissa D; Arinaitwe, Emmanuel; Kamya, Moses; Tappero, Jordan; Staedke, Sarah G; Dorsey, Grant; Greenhouse, Bryan; Rosenthal, Philip J

Evaluation of non-extracted genital swabs for real-time HSV PCR. (2014) Miari, Victoria F; Wall, Gavin R; Clark, Duncan A

April 2014

Surveillance and diagnosis of plague and anthrax in Tanzania and Zambia. (2014) Hang'ombe, BM; Ziwa, M; Haule, M; Nakamura, I; Samui, KL; Kaile, D; Mweene, AS; Kilonzo, BS; Lyamuya, EF; Matee, M; Sugimoto, C; Sawa, H; Wren, BW

Evaluation of the comparative efficacy and safety of artemether-lumefantrine, artesunate-amodiaquine and artesunate-amodiaquine-chlorpheniramine (Artemoclo™) for the treatment of acute uncomplicated malaria in Nigerian children. (2014) Falade, CO; Dada-Adegbola, HO; Ogunkunle, OO; Oguike, MC; Nash, O; Ademowo, OG

Staphylococcal phenotypes induced by naturally occurring and synthetic membrane-interactive polyphenolic β-lactam resistance modifiers. (2014) Palacios, Lucia; Rosado, Helena; Micol, Vicente; Rosato, Adriana E; Bernal, Patricia; Arroyo, Raquel; Grounds, Helen; Anderson, James C; Stabler, Richard A; Taylor, Peter W

March 2014

Genome-wide analysis of selection on the malaria parasite Plasmodium falciparum in West African populations of differing infection endemicity. (2014) Mobegi, Victor A; Duffy, Craig W; Amambua-Ngwa, Alfred; Loua, Kovana M; Laman, Eugene; Nwakanma, Davis C; MacInnis, Bronwyn; Aspeling-Jones, Harvey; Murray, Lee; Clark, Taane G; Kwiatkowski, Dominic P; Conway, David J

Implementing antiretroviral resistance testing in a primary health care HIV treatment programme in rural KwaZulu-Natal, South Africa: early experiences, achievements and challenges. (2014) Lessells, Richard J; Stott, Katharine E; Manasa, Justen; Naidu, Kevindra K; Skingsley, Andrew; Rossouw, Theresa; de Oliveira, Tulio; Southern African Treatment and Resistance Network (SATuRN)

February 2014

Capitation combined with pay-for-performance improves antibiotic prescribing practices in rural China. (2014) Yip, Winnie; Powell-Jackson, Timothy; Chen, Wen; Hu, Min; Fe, Eduardo; Hu, Mu; Jian, Weiyan; Lu, Ming; Han, Wei; Hsiao, William C

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. (2014) Moule, Madeleine G; Hemsley, Claudia M; Seet, Qihui; Guerra-Assunção, José Afonso; Lim, Jiali; Sarkar-Tyson, Mitali; Clark, Taane G; Tan, Patrick BO; Titball, Richard W; Cuccui, Jon; Wren, Brendan W

Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa. (2014) Manasa, Justen; Lessells, Richard; Rossouw, Theresa; Naidu, Kevindra; Van Vuuren, Cloete; Goedhals, Dominique; van Zyl, Gert; Bester, Armand; Skingsley, Andrew; Stott, Katharine; Danaviah, Siva; Chetty, Terusha; Singh, Lavanya; Moodley, Pravi; Iwuji, Collins; McGrath, Nuala; Seebregts, Christopher J; de Oliveira, Tulio

Prediction of Staphylococcus aureus antimicrobial resistance by whole-genome sequencing. (2014) Gordon, NC; Price, JR; Cole, K; Everitt, R; Morgan, M; Finney, J; Kearns, AM; Pichon, B; Young, B; Wilson, DJ; Llewelyn, MJ; Paul, J; Peto, TEA; Crook, DW; Walker, AS; Golubchik, T

January 2014

Benznidazole-resistance in Trypanosoma cruzi: evidence that distinct mechanisms can act in concert. (2014) Campos, Mônica CO; Leon, Leonor L; Taylor, Martin C; Kelly, John M

Drug resistance in children at virological failure in a rural KwaZulu-Natal, South Africa, cohort. (2014) Pillay, Sureshnee; Bland, Ruth M; Lessells, Richard J; Manasa, Justen; de Oliveira, Tulio; Danaviah, Sivapragashini

Effect of azithromycin mass drug administration for trachoma on spleen rates in Gambian children. (2014) Hart, John D; Edwards, Tansy; Burr, Sarah E; Harding-Esch, Emma M; Takaoka, Kensuke; Holland, Martin J; Sillah, Ansumana; Mabey, David CW; Bailey, Robin L

2014

Antibiotic resistance needs global solutions. (2014) Aiken, Alexander M; Allegranzi, Benedetta; Scott, J Anthony; Mehtar, Shaheen; Pittet, Didier; Grundmann, Hajo

Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia. (2014) Alifrangis, Michael; Nag, Sidsel; Schousboe, Mette L; Ishengoma, Deus; Lusingu, John; Pota, Hirva; Kavishe, Reginald A; Pearce, Richard; Ord, Rosalynn; Lynch, Caroline; Dejene, Seyoum; Cox, Jonathan; Rwakimari, John; Minja, Daniel TR; Lemnge, Martha M; Roper, Cally

Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis. (2014) Alsford, Sam

Emerging paradigms in anti-infective drug design. (2014) Barrett, Michael P; Croft, Simon L

Is gonorrhea becoming untreatable? (2014) Blomquist, Paula Bianca; Miari, Victoria F; Biddulph, Jane P; Charalambous, Bambos M

Genome evolution and plasticity of Serratia marcescens, an important multidrug-resistant nosocomial pathogen. (2014) Iguchi, Atsushi; Nagaya, Yutaka; Pradel, Elizabeth; Ooka, Tadasuke; Ogura, Yoshitoshi; Katsura, Keisuke; Kurokawa, Ken; Oshima, Kenshiro; Hattori, Masahira; Parkhill, Julian; Sebaihia, Mohamed; Coulthurst, Sarah J; Gotoh, Naomasa; Thomson, Nicholas R; Ewbank, Jonathan J; Hayashi, Tetsuya

Molecular surveillance for artemisinin resistance in Africa. (2014) Roper, Cally; Alifrangis, Michael; Ariey, Frederic; Talisuna, Ambrose; Menard, Didier; Mercereau-Puijalon, Odile; Ringwald, Pascal