Items where the Publication is Trials
Number of items: 281.
Article
  • Long-term consistent use of a vaginal microbicide gel among HIV-1 sero-discordant couples in a phase III clinical trial (MDP 301) in rural south-west Uganda. (2013) Abaasa, Andrew; Crook, Angela; Gafos, Mitzy; Anywaine, Zacchaeus; Levin, Jonathan; Wandiembe, Symon; Nanoo, Ananta; Nunn, Andrew; McCormack, Sheena; Hayes, Richard; Kamali, Anatoli
  • Adapted motivational interviewing to improve the uptake of treatment for glaucoma in Nigeria: study protocol for a randomized controlled trial. (2014) Abdull, Mohammed M; Gilbert, Clare; McCambridge, Jim; Evans, Jennifer
  • A community mobilisation intervention to prevent violence against women and reduce HIV/AIDS risk in Kampala, Uganda (the SASA! Study): study protocol for a cluster randomised controlled trial. (2012) Abramsky, Tanya; Devries, Karen; Kiss, Ligia; Francisco, Leilani; Nakuti, Janet; Musuya, Tina; Kyegombe, Nambusi; Starmann, Elizabeth; Kaye, Dan; Michau, Lori; Watts, Charlotte
  • Study protocol for a phase 1/2, single-centre, double-blind, double-dummy, randomized, active-controlled, age de-escalation trial to assess the safety, tolerability and immunogenicity of a measles and rubella vaccine delivered by a microneedle patch in healthy adults (18 to 40 years), measles and rubella vaccine-primed toddlers (15 to 18 months) and measles and rubella vaccine-naïve infants (9 to 10 months) in The Gambia [Measles and Rubella Vaccine Microneedle Patch Phase 1/2 Age De-escalation Trial]. (2022) Adigweme, Ikechukwu; Akpalu, Edem; Yisa, Mohammed; Donkor, Simon; Jarju, Lamin B; Danso, Baba; Mendy, Anthony; Jeffries, David; Njie, Abdoulie; Bruce, Andrew; Royals, Michael; Goodson, James L; Prausnitz, Mark R; McAllister, Devin; Rota, Paul A; Henry, Sebastien; Clarke, Ed
  • Intravenous versus oral iron for iron deficiency anaemia in pregnant Nigerian women (IVON): study protocol for a randomised hybrid effectiveness-implementation trial. (2022) Afolabi, Bosede B; Babah, Ochuwa A; Akinajo, Opeyemi R; Adaramoye, Victoria O; Adeyemo, Titilope A; Balogun, Mobolanle; Banke-Thomas, Aduragbemi; Quao, Rachel A; Olorunfemi, Gbenga; Abioye, Ajibola I; Galadanci, Hadiza S; Sam-Agudu, Nadia A
  • Safety and effectiveness of delivering mass drug administration for helminths through the seasonal malaria chemoprevention platform among Senegalese children: study protocol for a randomised controlled trial. (2022) Afolabi, Muhammed O; Sow, Doudou; Ndiaye, Jean Louis A; Greenwood, Brian
  • Protocol for a cluster randomised trial in Madhya Pradesh, India: community health promotion and medical provision and impact on neonates (CHAMPION2); and support to rural India's public education system and impact on numeracy and literacy scores (STRIPES2). (2020) Agarwal, Arjun; Banerji, Rukmini; Boone, Peter; Elbourne, Diana; Fazzio, Ila; Frost, Chris; Gopal, Madan; Karnati, Sridevi; Nair, Rakhi; Reddy, Harshavardhan; Reddy, Padmanabh; Sharma, Dropti; Shekhawat, Sajjan Singh; Shivalli, Siddharudha
  • Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial. (2016) Alim, Mohammed; Lindley, Richard; Felix, Cynthia; Gandhi, Dorcas Beulah Chandramathy; Verma, Shweta Jain; Tugnawat, Deepak Kumar; Syrigapu, Anuradha; Anderson, Craig Stuart; Ramamurthy, Ramaprabhu Krishnappa; Langhorne, Peter; Murthy, Gudlavalleti Venkata Satyanarayana; Shamanna, Bindiganavale Ramaswamy; Hackett, Maree Lisa; Maulik, Pallab Kumar; Harvey, Lisa Anne; Jan, Stephen; Liu, Hueiming; Walker, Marion; Forster, Anne; Pandian, Jeyaraj Durai
  • The efficacy of a brief intervention in reducing hazardous drinking in working age men in Russia: the HIM (Health for Izhevsk men) individually randomised parallel group exploratory trial. (2011) Allen, Elizabeth; Polikina, Olga; Saburova, Lyudmila; McCambridge, Jim; Elbourne, Diana; Pakriev, Sergey; Nekrasova, Nadezhda; Vasilyev, Maxim; Tomlin, Keith; Oralov, Alexey; Gil, Artyom; McKee, Martin; Kiryanov, Nikolay; Leon, David A picture_as_pdf
  • Protocol for an automated, pragmatic, embedded, adaptive randomised controlled trial: behavioural economics-informed mobile phone-based reminder messages to improve clinic attendance in a Botswanan school-based vision screening programme. (2022) Allen, Luke N; Ratshaa, Bakgaki; Macleod, David; Bolster, Nigel; Burton, Matthew; Kim, Min; Bastawrous, Andrew; Ho-Foster, Ari; Chroston, Hannah; Nkomazana, Oathokwa
  • Generalizing boundaries for triangular designs, and efficacy estimation at extended follow-ups. (2015) Allison, Annabel; Edwards, Tansy; Omollo, Raymond; Alves, Fabiana; Magirr, Dominic; E Alexander, Neal D
  • Update to the AWED (Applying Wolbachia to Eliminate Dengue) trial study protocol: a cluster randomised controlled trial in Yogyakarta, Indonesia. (2020) Anders, Katherine L; Indriani, Citra; Ahmad, Riris Andono; Tantowijoyo, Warsito; Arguni, Eggi; Andari, Bekti; Jewell, Nicholas P; Dufault, Suzanne M; Ryan, Peter A; Tanamas, Stephanie K; Rancès, Edwige; O'Neill, Scott L; Simmons, Cameron P; Utarini, Adi
  • The AWED trial (Applying Wolbachia to Eliminate Dengue) to assess the efficacy of Wolbachia-infected mosquito deployments to reduce dengue incidence in Yogyakarta, Indonesia: study protocol for a cluster randomised controlled trial. (2018) Anders, Katherine L; Indriani, Citra; Ahmad, Riris Andono; Tantowijoyo, Warsito; Arguni, Eggi; Andari, Bekti; Jewell, Nicholas P; Rances, Edwige; O'Neill, Scott L; Simmons, Cameron P; Utarini, Adi
  • European society of intensive care medicine study of therapeutic hypothermia (32-35 °C) for intracranial pressure reduction after traumatic brain injury (the Eurotherm3235Trial). (2011) Andrews, Peter JD; Sinclair, Helen Louise; Battison, Claire G; Polderman, Kees H; Citerio, Giuseppe; Mascia, Luciana; Harris, Bridget A; Murray, Gordon D; Stocchetti, Nino; Menon, David K; Shakur, Haleema; De Backer, Daniel; Eurotherm3235Trial collaborators
  • School-based intervention to improve the mental health of low-income, secondary school students in Santiago, Chile (YPSA): study protocol for a randomized controlled trial. (2011) Araya, Ricardo; Montgomery, Alan A; Fritsch, Rosemarie; Gunnell, David; Stallard, Paul; Noble, Sian; Martinez, Vania; Barroilhet, Sergio; Vohringer, Paul; Guajardo, Viviana; Cova, Felix; Gaete, Jorge; Gomez, Alejandro; Rojas, Graciela
  • The quality of reporting in cluster randomised crossover trials: proposal for reporting items and an assessment of reporting quality. (2016) Arnup, Sarah J; Forbes, Andrew B; Kahan, Brennan C; Morgan, Katy E; McKenzie, Joanne E
  • Community-based Rehabilitation Intervention for people with Schizophrenia in Ethiopia (RISE): study protocol for a cluster randomised controlled trial. (2016) Asher, Laura; De Silva, Mary; Hanlon, Charlotte; Weiss, Helen A; Birhane, Rahel; Ejigu, Dawit A; Medhin, Girmay; Patel, Vikram; Fekadu, Abebaw
  • Attractive targeted sugar bait phase III trials in Kenya, Mali, and Zambia. (2022) Attractive Targeted Sugar Bait Phase III Trial Group
  • ZAMSTAR, The Zambia South Africa TB and HIV Reduction Study: design of a 2 x 2 factorial community randomized trial. (2008) Ayles, Helen M; Sismanidis, Charalambos; Beyers, Nulda; Hayes, Richard J; Godfrey-Faussett, Peter
  • Correction to: Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries. (2021) Badio, Moses; Lhomme, Edouard; Kieh, Mark; Beavogui, Abdoul Habib; Kennedy, Stephen B; Doumbia, Seydou; Leigh, Bailah; Sow, Samba O; Diallo, Alpha; Fusco, Daniela; Kirchoff, Matthew; Termote, Monique; Vatrinet, Renaud; Wentworth, Deborah; Esperou, Helène; Lane, H Clifford; Pierson, Jerome; Watson-Jones, Deborah; Roy, Céline; D'Ortenzio, Eric; Greenwood, Brian; Chêne, Genevieve; Richer, Laura; Neaton, James D; Yazdanpanah, Yazdan; PREVAC study team
  • Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries. (2021) Badio, Moses; Lhomme, Edouard; Kieh, Mark; Beavogui, Abdoul Habib; Kennedy, Stephen B; Doumbia, Seydou; Leigh, Bailah; Sow, Samba O; Diallo, Alpha; Fusco, Daniela; Kirchoff, Matthew; Termote, Monique; Vatrinet, Renaud; Wentworth, Deborah; Esperou, Helène; Lane, H Clifford; Pierson, Jerome; Watson-Jones, Deborah; Roy, Céline; D'Ortenzio, Eric; Greenwood, Brian; Chêne, Genevieve; Richert, Laura; Neaton, James D; Yazdanpanah, Yazdan; PREVAC study team
  • Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial. (2012) Bahl, R; Bhandari, N; Dube, B; Edmond, K; Fawzi, W; Fontaine, O; Kaur, J; Kirkwood, BR; Martines, J; Masanja, H; Mazumder, S; Msham, S; Newton, S; Oleary, M; Ruben, J; Shannon, C; Smith, E; Taneja, S; Yoshida, S
  • Combined Protocol for Acute Malnutrition Study (ComPAS) in rural South Sudan and urban Kenya: study protocol for a randomized controlled trial. (2018) Bailey, Jeanette; Lelijveld, Natasha; Marron, Bethany; Onyoo, Pamela; Ho, Lara S; Manary, Mark; Briend, André; Opondo, Charles; Kerac, Marko
  • Sample size calculation for a stepped wedge trial. (2015) Baio, Gianluca; Copas, Andrew; Ambler, Gareth; Hargreaves, James; Beard, Emma; Omar, Rumana Z
  • Informal Health Provider and Practical Approach to Lung Health interventions to improve the detection of chronic airways disease and tuberculosis at primary care level in Malawi: study protocol for a randomised controlled trial. (2015) Banda, Hastings T; Mortimer, Kevin; Bello, George AF; Mbera, Grace B; Namakhoma, Ireen; Thomson, Rachael; Nyirenda, Moffat J; Faragher, Brian; Madan, Jason; Malmborg, Rasmus; Stenberg, Berthe; Mpunga, James; Mwagomba, Beatrice; Gama, Elvis; Piddock, Katherine; Squire, Stephen B
  • First steps: study protocol for a randomized controlled trial of the effectiveness of the Group Family Nurse Partnership (gFNP) program compared to routine care in improving outcomes for high-risk mothers and their children and preventing abuse. (2013) Barnes, Jacqueline; Aistrop, Dipti; Allen, Elizabeth; Barlow, Jane; Elbourne, Diana; Macdonald, Geraldine; Melhuish, Edward; Petrou, Stavros; Pink, Joshua; Snowdon, Claire; Spiby, Helen; Stuart, Jane; Sturgess, Joanna
  • Randomized controlled trial and economic evaluation of nurse-led group support for young mothers during pregnancy and the first year postpartum versus usual care. (2017) Barnes, Jacqueline; Stuart, Jane; Allen, Elizabeth; Petrou, Stavros; Sturgess, Joanna; Barlow, Jane; Macdonald, Geraldine; Spiby, Helen; Aistrop, Dipti; Melhuish, Edward; Kim, Sung Wook; Elbourne, Diana
  • Safety of tubal ligation by minilaparotomy provided by clinical officers versus assistant medical officers: study protocol for a noninferiority randomized controlled trial in Tanzanian women. (2017) Barone, Mark A; Mbuguni, Zuhura; Achola, Japhet Ominde; Cordero, Carmela; Kanama, Joseph; Muganyizi, Projestine S; Mwanga, Jamilla; Shannon, Caitlin; Tibyehabwa, Leopold
  • Stepped wedge randomised controlled trials: systematic review of studies published between 2010 and 2014. (2015) Beard, Emma; Lewis, James J; Copas, Andrew; Davey, Calum; Osrin, David; Baio, Gianluca; Thompson, Jennifer A; Fielding, Katherine L; Omar, Rumana Z; Ononge, Sam; Hargreaves, James; Prost, Audrey
  • Trial management: we need a cadre of high-class triallists to deliver the answers that patients need. (2019) Beaumont, Danielle; Arribas, Monica; Frimley, Lauren; Balogun, Eni; Roberts, Ian; Shakur-Still, Haleema
  • TB-PRACTECAL: study protocol for a randomised, controlled, open-label, phase II-III trial to evaluate the safety and efficacy of regimens containing bedaquiline and pretomanid for the treatment of adult patients with pulmonary multidrug-resistant tuberculosis. (2022) Berry, Catherine; du Cros, Philipp; Fielding, Katherine; Gajewski, Suzanne; Kazounis, Emil; McHugh, Timothy D; Merle, Corinne; Motta, Ilaria; Moore, David AJ; Nyang'wa, Bern-Thomas
  • Prevention of Decline in Cognition after Stroke Trial (PODCAST): a study protocol for a factorial randomised controlled trial of intensive versus guideline lowering of blood pressure and lipids. (2013) Blackburn, Daniel J; Krishnan, Kailash; Fox, Lydia; Ballard, Clive; Burns, Alistair; Ford, Gary A; Mant, Jonathan; Passmore, Peter; Pocock, Stuart; Reckless, John; Sprigg, Nikola; Stewart, Rob; Wardlaw, Joanna; Bath, Philip MW
  • Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme). (2019) Blackshaw, Helen; Vennik, Jane; Philpott, Carl; Thomas, Mike; Eyles, Caroline; Carpenter, James; Clarke, Caroline S; Morris, Steve; Schilder, Anne; Lund, Valerie; Little, Paul; Durham, Stephen; Denaxas, Spiros; Williamson, Elizabeth; Beard, David; Cook, Jonathan; Le Conte, Steffi; Airey, Kim; Boardman, Jim; Hopkins, Claire
  • Interventions in randomised controlled trials in surgery: issues to consider during trial design. (2015) Blencowe, Natalie S; Brown, Julia M; Cook, Jonathan A; Metcalfe, Chris; Morton, Dion G; Nicholl, Jon; Sharples, Linda D; Treweek, Shaun; Blazeby, Jane M; Members of the MRC Hub for Trials Methodology Research Network W
  • How 'place' matters for addressing the HIV epidemic: evidence from the HPTN 071 (PopART) cluster-randomised controlled trial in Zambia and South Africa. (2021) Bond, Virginia; Hoddinott, Graeme; Viljoen, Lario; Ngwenya, Fredrick; Simuyaba, Melvin; Chiti, Bwalya; Ndubani, Rhoda; Makola, Nozizwe; Donnell, Deborah; Schaap, Ab; Floyd, Sian; Hargreaves, James; Shanaube, Kwame; Fidler, Sarah; Bock, Peter; Ayles, Helen; Hayes, Richard; Simwinga, Musonda; Seeley, Janet; HPTN071 (PopART) study team
  • Initiating change locally in bullying and aggression through the school environment (INCLUSIVE): study protocol for a cluster randomised controlled trial. (2014) Bonell, Chris; Allen, Elizabeth; Christie, Deborah; Elbourne, Diana; Fletcher, Adam; Grieve, Richard; LeGood, Rosa; Mathiot, Anne; Scott, Stephen; Wiggins, Meg; Viner, Russell M
  • Initiating change locally in bullying and aggression through the school environment (INCLUSIVE) trial: update to cluster randomised controlled trial protocol. (2017) Bonell, Chris; Mathiot, Anne; Allen, Elizabeth; Bevilacqua, Leonardo; Christie, Deborah; Elbourne, Diana; Fletcher, Adam; Grieve, Richard; Legood, Rosa; Scott, Stephen; Warren, Emily; Wiggins, Meg; Viner, Russell M
  • Are randomised controlled trials positivist? Reviewing the social science and philosophy literature to assess positivist tendencies of trials of social interventions in public health and health services. (2018) Bonell, Chris; Moore, Graham; Warren, Emily; Moore, Laurence
  • Realist trials and the testing of context-mechanism-outcome configurations: a response to Van Belle et al. (2016) Bonell, Chris; Warren, Emily; Fletcher, Adam; Viner, Russell
  • Remedial after-school support classes offered in rural Gambia (The SCORE trial): study protocol for a cluster randomized controlled trial. (2015) Boone, Peter; Camara, Alpha; Eble, Alex; Elbourne, Diana; Fernandes, Samory; Frost, Chris; Jayanty, Chitra; Lenin, Maitri; Silva, Ana Filipa
  • The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial. (2013) Bousema, Teun; Stevenson, Jennifer; Baidjoe, Amrish; Stresman, Gillian; Griffin, Jamie T; Kleinschmidt, Immo; Remarque, Edmond J; Vulule, John; Bayoh, Nabie; Laserson, Kayla; Desai, Meghna; Sauerwein, Robert; Drakeley, Chris; Cox, Jonathan
  • Perspectives on the design and methodology of periconceptional nutrient supplementation trials. (2016) Brabin, Bernard J; Gies, Sabine; Owens, Stephen; Claeys, Yves; D'Alessandro, Umberto; Tinto, Halidou; Brabin, Loretta
  • Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. (2019) Brenner, Amy; Afolabi, Adefemi; Ahmad, Syed Masroor; Arribas, Monica; Chaudhri, Rizwana; Coats, Timothy; Cuzick, Jack; Gilmore, Ian; Hawkey, Christopher; Jairath, Vipul; Javaid, Kiran; Kayani, Aasia; Mutti, Muttiullah; Nadeem, Muhammad Arif; Shakur-Still, Haleema; Stanworth, Simon; Veitch, Andrew; Roberts, Ian; HALT-IT Trial Collaborators
  • Outcome measures in clinical trials of treatments for acute severe haemorrhage. (2018) Brenner, Amy; Arribas, Monica; Cuzick, Jack; Jairath, Vipul; Stanworth, Simon; Ker, Katharine; Shakur-Still, Haleema; Roberts, Ian
  • Postpartum haemorrhage in anaemic women: assessing outcome measures for clinical trials. (2022) Brenner, Amy; Roberts, Ian; Balogun, Eni; Bello, Folasade Adenike; Chaudhri, Rizwana; Fleming, Charlotte; Javaid, Kiran; Kayani, Aasia; Lubeya, Mwansa Ketty; Mansukhani, Raoul; Olayemi, Oladapo; Prowse, Danielle; Vwalika, Bellington; Shakur-Still, Haleema
  • Psychological advocacy toward healing (PATH): study protocol for a randomized controlled trial. (2013) Brierley, Gwen; Agnew-Davies, Roxane; Bailey, Jayne; Evans, Maggie; Fackrell, Morgan; Ferrari, Giulia; Hollinghurst, Sandra; Howard, Louise; Howarth, Emma; Malpass, Alice; Metters, Carol; Peters, Tim J; Saeed, Fayeza; Sardhina, Lynnmarie; Sharp, Debbie; Feder, Gene S
  • Improving educational achievement and anaemia of school children: design of a cluster randomised trial of school-based malaria prevention and enhanced literacy instruction in Kenya. (2010) Brooker, Simon; Okello, George; Njagi, Kiambo; Dubeck, Margaret M; Halliday, Katherine E; Inyega, Hellen; Jukes, Matthew CH
  • Protocol for a randomised trial of early kangaroo mother care compared to standard care on survival of pre-stabilised preterm neonates in The Gambia (eKMC). (2020) Brotherton, Helen; Gai, Abdou; Tann, Cally J; Samateh, Ahmadou Lamin; Seale, Anna C; Zaman, Syed MA; Cousens, Simon; Roca, Anna; Lawn, Joy E
  • Effectiveness of an implementation optimisation intervention aimed at increasing parent engagement in HENRY, a childhood obesity prevention programme - the Optimising Family Engagement in HENRY (OFTEN) trial: study protocol for a randomised controlled trial. (2017) Bryant, Maria; Burton, Wendy; Cundill, Bonnie; Farrin, Amanda J; Nixon, Jane; Stevens, June; Roberts, Kim; Foy, Robbie; Rutter, Harry; Hartley, Suzanne; Tubeuf, Sandy; Collinson, Michelle; Brown, Julia
  • Fracture risk and the use of a diuretic (indapamide SR) +/- perindopril: a substudy of the Hypertension in the Very Elderly Trial (HYVET). (2006) Bulpitt, Christopher J; Peters, Ruth; Staessen, Jan A; Thijs, Lutgarde; De Vernejoul, Marie-Christine; Fletcher, Astrid E; Beckett, Nigel S picture_as_pdf
  • When assessing generalisability, focusing on differences in population or setting alone is insufficient. (2020) Burchett, Helen ED; Kneale, Dylan; Blanchard, Laurence; Thomas, James
  • Developing a placebo-controlled trial in surgery: issues of design, acceptability and feasibility. (2011) Campbell, MK; Entwistle, VA; Cuthbertson, BH; Skea, ZC; Sutherland, AG; McDonald, AM; Norrie, JD; Carlson, RV; Bridgman, S; KORAL study group
  • The impact of maintaining serum potassium ≥3.6 mEq/L vs ≥4.5 mEq/L on the incidence of new-onset atrial fibrillation in the first 120 hours after isolated elective coronary artery bypass grafting - study protocol for a randomised feasibility trial for the proposed Tight K randomized non-inferiority trial. (2017) Campbell, Niall G; Allen, Elizabeth; Sanders, Julie; Swinson, Rebecca; Birch, Sophie; Sturgess, Joanna; Al-Subaie, Nawaf; Elbourne, Diana; Montgomery, Hugh; O'Brien, Ben
  • Evaluation of exercise on individuals with dementia and their carers: a randomised controlled trial. (2010) Cerga-Pashoja, Arlinda; Lowery, David; Bhattacharya, Rahul; Griffin, Mark; Iliffe, Steve; Lee, James; Leonard, Claire; Ricketts, Sue; Strother, Lyn; Waters, Fiona; Ritchie, Craig W; Warner, James
  • Tailored, psychological intervention for anxiety and/or depression in people with chronic obstructive pulmonary disease (COPD), TANDEM (Tailored intervention for ANxiety and DEpression Management in COPD): statistical analysis plan for a randomised controlled trial. (2020) Chan, Claire L; Smuk, Melanie; Sohanpal, Ratna; Pinnock, Hilary; Taylor, Stephanie JC; TANDEM Investigators
  • Collaborative community based care for people and their families living with schizophrenia in India: protocol for a randomised controlled trial. (2011) Chatterjee, Sudipto; Leese, Morven; Koschorke, Mirja; McCrone, Paul; Naik, Smita; John, Sujit; Dabholkar, Hamid; Goldsmith, Kimberley; Balaji, Madhumitha; Varghese, Mathew; Thara, Rangaswamy; Patel, Vikram; Thornicroft, Graham; COmmunity care for People with Schizophrenia in India (COPSI) gr picture_as_pdf
  • The 2nd European Carotid Surgery Trial (ECST-2): rationale and protocol for a randomised clinical trial comparing immediate revascularisation versus optimised medical therapy alone in patients with symptomatic and asymptomatic carotid stenosis at low to intermediate risk of stroke. (2022) Cheng, Suk Fun; van Velzen, Twan J; Gregson, John; Richards, Toby; Jäger, Hans Rolf; Simister, Robert; Kooi, M Eline; de Borst, Gert J; Pizzini, Francesca B; Nederkoorn, Paul J; Brown, Martin M; Bonati, Leo H
  • Addressing challenges in tuberculosis adherence via performance-based payments for integrated case management: protocol for a cluster randomized controlled trial in Georgia. (2019) Chikovani, Ivdity; Diaconu, Karin; Duric, Predrag; Sulaberidze, Lela; Uchaneishvili, Maia; Mohammed, Nuredin Ibrahim; Zoidze, Akaki; Witter, Sophie
  • Investigating interventions to increase uptake of HIV testing and linkage into care or prevention for male partners of pregnant women in antenatal clinics in Blantyre, Malawi: study protocol for a cluster randomised trial. (2017) Choko, Augustine T; Fielding, Katherine; Stallard, Nigel; Maheswaran, Hendramoorthy; Lepine, Aurelia; Desmond, Nicola; Kumwenda, Moses K; Corbett, Elizabeth L
  • Assessing the efficacy of the healthy eating and lifestyle programme (HELP) compared with enhanced standard care of the obese adolescent in the community: study protocol for a randomized controlled trial. (2011) Christie, Deborah; Hudson, Lee; Mathiot, Anne; Cole, Tim J; Karlsen, Saffron; Kessel, A; Kinra, Sanjay; Morris, Steve; Nazareth, Irwin; Sovio, Ulla; Wong, Ian CK; Viner, Russell M
  • Assessing the efficacy of the Healthy Eating and Lifestyle Programme (HELP) compared with enhanced standard care of the obese adolescent in the community: study protocol for a randomized controlled trial. (2011) Christie, Deborah; Hudson, Lee; Mathiot, Anne; Cole, Tim J; Karlsen, Saffron; Kessel, Anthony; Kinra, Sanjay; Morris, Steve; Nazareth, Irwin; Sovio, Ulla; Wong, Ian CK; Viner, Russell M
  • CRASH2 in Germany [ISRCTN86750102]. (2006) Chung, CH; Freiberger, A; Kalkum, M; Luntz, SP; Shakur, H; Seiler, CM
  • The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials. (2017) Clayton, Gemma L; Smith, Isabelle L; Higgins, Julian PT; Mihaylova, Borislava; Thorpe, Benjamin; Cicero, Robert; Lokuge, Kusal; Forman, Julia R; Tierney, Jayne F; White, Ian R; Sharples, Linda D; Jones, Hayley E
  • The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments. (2011) Connick, Peter; Kolappan, Madhan; Patani, Rickie; Scott, Michael A; Crawley, Charles; He, Xiao-Ling; Richardson, Karen; Barber, Kelly; Webber, Daniel J; Wheeler-Kingshott, Claudia AM; Tozer, Daniel J; Samson, Rebecca S; Thomas, David L; Du, Ming-Qing; Luan, Shi L; Michell, Andrew W; Altmann, Daniel R; Thompson, Alan J; Miller, David H; Compston, Alastair; Chandran, Siddharthan
  • Designing a stepped wedge trial: three main designs, carry-over effects and randomisation approaches. (2015) Copas, Andrew J; Lewis, James J; Thompson, Jennifer A; Davey, Calum; Baio, Gianluca; Hargreaves, James R
  • Uthando Lwethu ('our love'): a protocol for a couples-based intervention to increase testing for HIV: a randomized controlled trial in rural KwaZulu-Natal, South Africa. (2014) Darbes, Lynae A; van Rooyen, Heidi; Hosegood, Victoria; Ngubane, Thulani; Johnson, Mallory O; Fritz, Katherine; McGrath, Nuala
  • Analysis and reporting of stepped wedge randomised controlled trials: synthesis and critical appraisal of published studies, 2010 to 2014. (2015) Davey, Calum; Hargreaves, James; Thompson, Jennifer A; Copas, Andrew J; Beard, Emma; Lewis, James J; Fielding, Katherine L
  • Beyond interviews and focus groups: a framework for integrating innovative qualitative methods into randomised controlled trials of complex public health interventions. (2019) Davis, Katy; Minckas, Nicole; Bond, Virginia; Clark, Cari Jo; Colbourn, Tim; Drabble, Sarah J; Hesketh, Therese; Hill, Zelee; Morrison, Joanna; Mweemba, Oliver; Osrin, David; Prost, Audrey; Seeley, Janet; Shahmanesh, Maryam; Spindler, Esther J; Stern, Erin; Turner, Katrina M; Mannell, Jenevieve
  • Theory of Change: a theory-driven approach to enhance the Medical Research Council's framework for complex interventions. (2014) De Silva, Mary J; Breuer, Erica; Lee, Lucy; Asher, Laura; Chowdhary, Neerja; Lund, Crick; Patel, Vikram
  • The Good Schools Toolkit to prevent violence against children in Ugandan primary schools: study protocol for a cluster randomised controlled trial. (2013) Devries, Karen M; Allen, Elizabeth; Child, Jennifer C; Walakira, Eddy; Parkes, Jenny; Elbourne, Diana; Watts, Charlotte; Naker, Dipak
  • "I never expected that it would happen, coming to ask me such questions":Ethical aspects of asking children about violence in resource poor settings. (2015) Devries, Karen M; Child, Jennifer C; Elbourne, Diana; Naker, Dipak; Heise, Lori
  • Complier-average causal effects for multivariate outcomes: an instrumental variable approach with application to health economics. (2015) DiazOrdaz, Karla; Franchini, Angelo; Grieve, Richard
  • An analysis of baseline data from the PROUD study: an open-label randomised trial of pre-exposure prophylaxis. (2016) Dolling, David I; Desai, Monica; McOwan, Alan; Gilson, Richard; Clarke, Amanda; Fisher, Martin; Schembri, Gabriel; Sullivan, Ann K; Mackie, Nicola; Reeves, Iain; Portman, Mags; Saunders, John; Fox, Julie; Bayley, Jake; Brady, Michael; Bowman, Christine; Lacey, Charles J; Taylor, Stephen; White, David; Antonucci, Simone; Gafos, Mitzy; McCormack, Sheena; Gill, Owen N; Dunn, David T; Nardone, Anthony; PROUD Study Group
  • Cluster randomized trial in the general practice research database: 2. Secondary prevention after first stroke (eCRT study): study protocol for a randomized controlled trial. (2012) Dregan, Alex; van Staa, Tjeerd; McDermott, Lisa; McCann, Gerard; Ashworth, Mark; Charlton, Judith; Wolfe, Charles; Rudd, Anthony; Yardley, Lucy; Gulliford, Martin; eCRT Research Team
  • The STRIPES trial--support to rural India's public education system. (2010) Eble, Alex; Mann, Vera; Bhakta, Preetha; Lakshminarayana, Rashmi; Frost, Chris; Elbourne, Diana; Boone, Peter
  • Trends in clinical trial registration in sub-Saharan Africa between 2010 and 2020: a cross-sectional review of three clinical trial registries. (2021) Edem, Bassey; Onwuchekwa, Chukwuemeka; Wariri, Oghenebrume; Nkereuwem, Esin; Nkereuwem, Oluwatosin O; Williams, Victor
  • Including random centre effects in design, analysis and presentation of multi-centre trials. (2021) Edgar, Kate; Roberts, Ian; Sharples, Linda
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  • Reducing research waste by promoting informed responses to invitations to participate in clinical trials. (2019) Elbourne, Diana
  • Recruiting for research on sensitive topics in schools: an experience with Vaxcards, a collectable vaccine card game. (2021) Epstein, DS; Enticott, JC; Larson, HJ; Barton, C
  • Process evaluation of a knowledge translation intervention using facilitation of local stakeholder groups to improve neonatal survival in the Quang Ninh province, Vietnam. (2016) Eriksson, Leif; Huy, Tran Q; Duc, Duong M; Ekholm Selling, Katarina; Hoa, Dinh P; Thuy, Nguyen T; Nga, Nguyen T; Persson, Lars-Åke; Wallin, Lars
  • Application of causal inference methods in the analyses of randomised controlled trials: a systematic review. (2018) Farmer, Ruth E; Kounali, Daphne; Walker, A Sarah; Savović, Jelena; Richards, Alison; May, Margaret T; Ford, Deborah
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  • Evaluation of a point-of-care tuberculosis test-and-treat algorithm on early mortality in people with HIV accessing antiretroviral therapy (TB Fast Track study): study protocol for a cluster randomised controlled trial. (2015) Fielding, Katherine L; Charalambous, Salome; Hoffmann, Christopher J; Johnson, Suzanne; Tlali, Mpho; Dorman, Susan E; Vassall, Anna; Churchyard, Gavin J; Grant, Alison D
  • Statistical analysis plan for the 'Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage' (TICH-2) trial. (2017) Flaherty, Katie; Bath, Philip M; Dineen, Robert; Law, Zhe; Scutt, Polly; Pocock, Stuart; Sprigg, Nikola; TICH-2 investigators
  • Marketing and clinical trials: a case study. (2007) Francis, David; Roberts, Ian; Elbourne, Diana R; Shakur, Haleema; Knight, Rosemary C; Garcia, Jo; Snowdon, Claire; Entwistle, Vikki A; McDonald, Alison M; Grant, Adrian M; Campbell, Marion K
  • A cluster randomized controlled trial for assessing POC-CCA test based praziquantel treatment for schistosomiasis control in pregnant women and their young children: study protocol of the freeBILy clinical trial in Madagascar. (2021) Fusco, Daniela; Rakotozandrindrainy, Raphäel; Rakotoarivelo, Rivo Andry; Andrianarivelo, Mala Rakoto; Rakotozandrindrainy, Njary; Rasamoelina, Tahinamandranto; Puradiredja, Dewi Ismajani; Klein, Philipp; Stahlberg, Karl; Dechenaud, Marie; Lorenz, Eva; Jaeger, Anna; Kreidenweiss, Andrea; Hoekstra, Pytsje T; Adegnika, Akim Ayola; Sicuri, Elisa; Corstjens, Paul LAM; van Dam, Govert J; May, Jürgen; Schwarz, Norbert Georg; freeBILy consortium
  • The KiVa antibullying program in primary schools in Chile, with and without the digital game component: study protocol for a randomized controlled trial. (2017) Gaete, Jorge; Valenzuela, Daniela; Rojas-Barahona, Cristian; Valenzuela, Eduardo; Araya, Ricardo; Salmivalli, Christina
  • The impact of improved water supply on cholera and diarrhoeal diseases in Uvira, Democratic Republic of the Congo: a protocol for a pragmatic stepped-wedge cluster randomised trial and economic evaluation. (2021) Gallandat, Karin; Jeandron, Aurélie; Ross, Ian; Mufitini Saidi, Jaime; Bashige Rumedeka, Baron; Lumami Kapepula, Vercus; Cousens, Simon; Allen, Elizabeth; MacDougall, Amy; Cumming, Oliver
  • Using marketing theory to inform strategies for recruitment: a recruitment optimisation model and the txt2stop experience. (2014) Galli, Leandro; Knight, Rosemary; Robertson, Steven; Hoile, Elizabeth; Oladapo, Olubukola; Francis, David; Free, Caroline
  • Improving diets and nutrition through an integrated poultry value chain and nutrition intervention (SELEVER) in Burkina Faso: study protocol for a randomized trial. (2017) Gelli, Aulo; Becquey, Elodie; Ganaba, Rasmane; Headey, Derek; Hidrobo, Melissa; Huybregts, Lieven; Verhoef, Hans; Kenfack, Romain; Zongouri, Sita; Guedenet, Hannah
  • Evaluation of alternative school feeding models on nutrition, education, agriculture and other social outcomes in Ghana: rationale, randomised design and baseline data. (2016) Gelli, Aulo; Masset, Edoardo; Folson, Gloria; Kusi, Anthoni; Arhinful, Daniel K; Asante, Felix; Ayi, Irene; Bosompem, Kwabena M; Watkins, Kristie; Abdul-Rahman, Lutuf; Agble, Rosanna; Ananse-Baden, Getrude; Mumuni, Daniel; Aurino, Elisabetta; Fernandes, Meena; Drake, Lesley
  • Reducing research waste by promoting informed responses to invitations to participate in clinical trials. (2019) Gillies, Katie; Chalmers, Iain; Glasziou, Paul; Elbourne, Diana; Elliott, Jim; Treweek, Shaun
  • COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials. (2019) Goldacre, Ben; Drysdale, Henry; Marston, Cicely; Mahtani, Kamal R; Dale, Aaron; Milosevic, Ioan; Slade, Eirion; Hartley, Philip; Heneghan, Carl
  • OpenTrials: towards a collaborative open database of all available information on all clinical trials. (2016) Goldacre, Ben; Gray, Jonathan
  • Azithromycin versus placebo for the treatment of HIV-associated chronic lung disease in children and adolescents (BREATHE trial): study protocol for a randomised controlled trial. (2017) Gonzalez-Martinez, Carmen; Kranzer, Katharina; McHugh, Grace; Corbett, Elizabeth L; Mujuru, Hilda; Nicol, Mark P; Rowland-Jones, Sarah; Rehman, Andrea M; Gutteberg, Tore J; Flaegstad, Trond; Odland, Jon O; Ferrand, Rashida A; BREATHE study team
  • The Early Youth Engagement in first episode psychosis (EYE-2) study: pragmatic cluster randomised controlled trial of implementation, effectiveness and cost-effectiveness of a team-based motivational engagement intervention to improve engagement. (2021) Greenwood, Kathryn; Webb, Rebecca; Gu, Jenny; Fowler, David; de Visser, Richard; Bremner, Stephen; Abramowicz, Iga; Perry, Nicky; Clark, Stuart; O'Donnell, Anastacia; Charlton, Dan; Jarvis, Rebecca; Garety, Philippa; Nandha, Sunil; Lennox, Belinda; Johns, Louise; Rathod, Shanaya; Phiri, Peter; French, Paul; Law, Heather; Hodgekins, Jo; Painter, Michelle; Treise, Cate; Plaistow, James; Irwin, Francis; Thompson, Rose; Mackay, Tanya; May, Carl R; Healey, Andy; Hooper, Richard; Peters, Emmanuelle
  • Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study). (2011) Gulliford, Martin C; van Staa, Tjeerd; McDermott, Lisa; Dregan, Alex; McCann, Gerard; Ashworth, Mark; Charlton, Judith; Grieve, Andrew P; Little, Paul; Moore, Michael V; Yardley, Lucy; electronic Cluster Randomised Trial Research Team eCRT Research
  • How context can impact clinical trials: a multi-country qualitative case study comparison of diagnostic biomarker test interventions. (2019) Haenssgen, Marco J; Charoenboon, Nutcha; Do, Nga TT; Althaus, Thomas; Khine Zaw, Yuzana; Wertheim, Heiman FL; Lubell, Yoel
  • Protocol for the cost-consequence and equity impact analyses of a cluster randomised controlled trial comparing three variants of a nutrition-sensitive agricultural extension intervention to improve maternal and child dietary diversity and nutritional status in rural Odisha, India (UPAVAN trial). (2019) Haghparast-Bidgoli, Hassan; Skordis, Jolene; Harris-Fry, Helen; Krishnan, Sneha; O'Hearn, Meghan; Kumar, Abhinav; Pradhan, Ronali; Mishra, Naba Kishore; Upadhyay, Avinash; Pradhan, Shibananth; Ojha, Amit Kumar; Cunningham, Sarah; Rath, Shibanand; Palmer, Tom; Koniz-Booher, Peggy; Kadiyala, Suneetha
  • Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons. (2019) Hague, Dominic; Townsend, Stephen; Masters, Lindsey; Rauchenberger, Mary; Van Looy, Nadine; Diaz-Montana, Carlos; Gannon, Melissa; James, Nicholas; Maughan, Tim; Parmar, Mahesh KB; Brown, Louise; Sydes, Matthew R; STAMPEDE and FOCUS4 investigators
  • The role of therapeutic optimism in recruitment to a clinical trial in a peripartum setting: balancing hope and uncertainty. (2016) Hallowell, Nina; Snowdon, Claire; Morrow, Susan; Norman, Jane E; Denison, Fiona C; Lawton, Julia
  • Evaluating the effect of the Helping Mothers Survive Bleeding after Birth (HMS BAB) training in Tanzania and Uganda: study protocol for a randomised controlled trial. (2017) Hanson, Claudia; Pembe, Andrea B; Alwy, Fadhlun; Atuhairwe, Susan; Leshabari, Sebalda; Morris, Jessica; Kaharuza, Frank; Marrone, Gaetano; HMS BAB study team
  • The added value of a mobile application of Community Case Management on referral, re-consultation and hospitalization rates of children aged under 5 years in two districts in Northern Malawi: study protocol for a pragmatic, stepped-wedge cluster-randomized controlled trial. (2017) Hardy, Victoria; O'Connor, Yvonne; Heavin, Ciara; Mastellos, Nikolaos; Tran, Tammy; O'Donoghue, John; Fitzpatrick, Annette L; Ide, Nicole; Wu, Tsung-Shu Joseph; Chirambo, Griphin Baxter; Muula, Adamson S; Nyirenda, Moffat; Carlsson, Sven; Andersson, Bo; Thompson, Matthew
  • Five questions to consider before conducting a stepped wedge trial. (2015) Hargreaves, James R; Copas, Andrew J; Beard, Emma; Osrin, David; Lewis, James J; Davey, Calum; Thompson, Jennifer A; Baio, Gianluca; Fielding, Katherine L; Prost, Audrey
  • Statistical design and analysis plan for an impact evaluation of an HIV treatment and prevention intervention for female sex workers in Zimbabwe: a study protocol for a cluster randomised controlled trial. (2016) Hargreaves, James R; Fearon, Elizabeth; Davey, Calum; Phillips, Andrew; Cambiano, Valentina; Cowan, Frances M
  • How important is randomisation in a stepped wedge trial? (2015) Hargreaves, James R; Prost, Audrey; Fielding, Katherine L; Copas, Andrew J
  • Exploring the role and function of trial steering committees: results of an expert panel meeting. (2015) Harman, Nicola L; Conroy, Elizabeth J; Lewis, Steff C; Murray, Gordon; Norrie, John; Sydes, Matt R; Lane, J Athene; Altman, Douglas G; Baigent, Colin; Bliss, Judith M; Campbell, Marion K; Elbourne, Diana; Evans, Stephen; Sandercock, Peter; Gamble, Carrol
  • HPTN 071 (PopART): rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment - a study protocol for a cluster randomised trial. (2014) Hayes, Richard; Ayles, Helen; Beyers, Nulda; Sabapathy, Kalpana; Floyd, Sian; Shanaube, Kwame; Bock, Peter; Griffith, Sam; Moore, Ayana; Watson-Jones, Deborah; Fraser, Christophe; Vermund, Sten H; Fidler, Sarah; HPTN 071 (PopART) Study Team
  • Prevention of Morbidity in Sickle Cell Disease (POMS2a)-overnight auto-adjusting continuous positive airway pressure compared with nocturnal oxygen therapy: a randomised crossover pilot study examining patient preference and safety in adults and children. (2019) Howard, Jo; Lee, Sophie A; Inusa, Baba; Cheng, Man Ying Edith; Bavenjit, Cheema; Reading, Isabel C; Wakeford, Sally Ann; Gavlak, Johanna C; Murphy, Patrick B; Hart, Nicholas; Gupta, Atul; Sahota, Sati; Jacob, Eufemia; Chorozoglou, Maria; Ossai, Carol; Gwam, Maureen; Kirkham, Fenella J; Wade, Angela M; Liossi, Christina
  • Determining the efficacy of guppies and pyriproxyfen (Sumilarv® 2MR) combined with community engagement on dengue vectors in Cambodia: study protocol for a randomized controlled trial. (2017) Hustedt, John; Doum, Dyna; Keo, Vanney; Ly, Sokha; Sam, BunLeng; Chan, Vibol; Alexander, Neal; Bradley, John; Prasetyo, Didot Budi; Rachmat, Agus; Muhammad, Shafique; Lopes, Sergio; Leang, Rithea; Hii, Jeffrey
  • Evaluation of the impact of immediate versus WHO recommendations-guided antiretroviral therapy initiation on HIV incidence: the ANRS 12249 TasP (Treatment as Prevention) trial in Hlabisa sub-district, KwaZulu-Natal, South Africa: study protocol for a cluster randomised controlled trial. (2013) Iwuji, Collins C; Orne-Gliemann, Joanna; Tanser, Frank; Boyer, Sylvie; Lessells, Richard J; Lert, France; Imrie, John; Bärnighausen, Till; Rekacewicz, Claire; Bazin, Brigitte; Newell, Marie-Louise; Dabis, François; ANRS 12249 TasP Study Group
  • Multicomponent intervention versus usual care for management of hypertension in rural Bangladesh, Pakistan and Sri Lanka: study protocol for a cluster randomized controlled trial. (2017) Jafar, Tazeen H; Jehan, Imtiaz; de Silva, H Asita; Naheed, Aliya; Gandhi, Mihir; Assam, Pryseley; Finkelstein, Eric A; Quigley, Helena Legido; Bilger, Marcel; Khan, Aamir Hameed; Clemens, John David; Ebrahim, Shah; Turner, Elizabeth L; for COBRA-BPS Study Group; Kasturiratne, Anuradhani
  • The three stages of building and testing mid-level theories in a realist RCT: a theoretical and methodological case-example. (2015) Jamal, Farah; Fletcher, Adam; Shackleton, Nichola; Elbourne, Diana; Viner, Russell; Bonell, Chris
  • Can selenium deficiency in Malawi be alleviated through consumption of agro-biofortified maize flour? Study protocol for a randomised, double-blind, controlled trial. (2019) Joy, Edward JM; Kalimbira, Alexander A; Gashu, Dawd; Ferguson, Elaine L; Sturgess, Joanna; Dangour, Alan D; Banda, Leonard; Chiutsi-Phiri, Gabriella; Bailey, Elizabeth H; Langley-Evans, Simon C; Lark, R Murray; Millar, Kate; Young, Scott D; Matandika, Limbanazo; Mfutso-Bengo, Joseph; Phuka, John C; Phiri, Felix P; Gondwe, Jellita; Ander, E Louise; Lowe, Nicola M; Nalivata, Patson C; Broadley, Martin R; Allen, Elizabeth
  • Can selenium deficiency in Malawi be alleviated through consumption of agro-biofortified maize flour? Study protocol for a randomised, double-blind, controlled trial. (2019) Joy, Edward; Kalimbira, Alexander; Gashu, Dawd; Ferguson, Elaine; Sturgess, Joanna; Dangour, Alan; Banda, Leonard; Chiutsi-Phiri, Gabriella; Bailey, Elizabeth; Langley-Evans, Simon; Lark, Murray; Millar, Kate; Young, Scott; Matandika, Limbanazo; Mfutso-Bengo, Joseph; Phuka, John; Phiri, Felix; Gondwe, Jellita; Ander, Louise; Lowe, Nicola; Nalivata, Patson; Broadley, Martin; Allen, Elizabeth
  • The effects of improved sanitation on diarrheal prevalence, incidence, and duration in children under five in the SNNPR State, Ethiopia: study protocol for a randomized controlled trial. (2016) Jung, Sunghoon; Doh, Young-Ah; Bizuneh, Dawit Belew; Beyene, Habtamu; Seong, Jieun; Kwon, Hyunjin; Kim, Yongwhan; Habteyes, Girma Negussie; Tefera, Yigrem; Cha, Seungman
  • Upscaling Participatory Action and Videos for Agriculture and Nutrition (UPAVAN) trial comparing three variants of a nutrition-sensitive agricultural extension intervention to improve maternal and child nutritional outcomes in rural Odisha, India: study protocol for a cluster randomised controlled trial. (2018) Kadiyala, Suneetha; Prost, Audrey; Harris-Fry, Helen; O'Hearn, Meghan; Pradhan, Ronali; Pradhan, Shibananth; Mishra, Naba Kishore; Rath, Suchitra; Nair, Nirmala; Rath, Shibanand; Tripathy, Prasantha; Krishnan, Sneha; Koniz-Booher, Peggy; Danton, Heather; Elbourne, Diana; Sturgess, Joanna; Beaumont, Emma; Haghparast-Bidgoli, Hassan; Skordis-Worrall, Jolene; Mohanty, Satyanarayan; Upadhay, Avinash; Allen, Elizabeth
  • Coping with persistent pain, effectiveness research into self-management (COPERS): statistical analysis plan for a randomised controlled trial. (2014) Kahan, Brennan C; Diaz-Ordaz, Karla; Homer, Kate; Carnes, Dawn; Underwood, Martin; Taylor, Stephanie Jc; Bremner, Stephen A; Eldridge, Sandra
  • Increased risk of type I errors in cluster randomised trials with small or medium numbers of clusters: a review, reanalysis, and simulation study. (2016) Kahan, Brennan C; Forbes, Gordon; Ali, Yunus; Jairath, Vipul; Bremner, Stephen; Harhay, Michael O; Hooper, Richard; Wright, Neil; Eldridge, Sandra M; Leyrat, Clémence
  • Menstrual health interventions, schooling, and mental health problems among Ugandan students (MENISCUS): study protocol for a school-based cluster-randomised trial. (2022) Kansiime, Catherine; Hytti, Laura; Nelson, Kate Andrews; Torondel, Belen; Francis, Suzanna C; Tanton, Clare; Greco, Giulia; Belfield, Sophie; Nakalema, Shamirah; Matovu, Fred; Ssemata, Andrew Sentoogo; Alezuyo, Connie; Neema, Stella; Jerrim, John; Bonell, Chris; Seeley, Janet; Weiss, Helen A; MENISCUS Group
  • Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial. (2018) Ker, Katharine; Roberts, Ian; Chaudhri, Rizwana; Fawole, Bukola; Beaumont, Danielle; Balogun, Eni; Prowse, Danielle; Pepple, Tracey; Javaid, Kiran; Kayani, Aasia; Arulkumaran, Sabaratnam; Bates, Imelda; Shakur-Still, Haleema; WOMAN-2 trial collaborators
  • 'Test n Treat (TnT)'- Rapid testing and same-day, on-site treatment to reduce rates of chlamydia in sexually active further education college students: study protocol for a cluster randomised feasibility trial. (2018) Kerry-Barnard, Sarah; Fleming, Charlotte; Reid, Fiona; Phillips, Rachel; Drennan, Vari M; Adams, Elisabeth J; Majewska, Wendy; Balendra, Anjella; Harding-Esch, Emma; Cousins, Emma; Tariq Sadiq, S; Oakeshott, Pippa
  • Lessons and implications from a mass immunization campaign in squatter settlements of Karachi, Pakistan: an experience from a cluster-randomized double-blinded vaccine trial [NCT00125047]. (2006) Khan, Mohammad Imran; Ochiai, Rion Leon; Hamza, Hasan Bin; Sahito, Shah Muhammad; Habib, Muhammad Atif; Soofi, Sajid Bashir; Bhutto, Naveed Sarwar; Rasool, Shahid; Puri, Mahesh K; Ali, Mohammad; Wasan, Shafi Mohammad; Khan, Mohammad Jawed; Abu-Elyazeed, Remon; Ivanoff, Bernard; Galindo, Claudia M; Pang, Tikki; Donner, Allan; von Seidlein, Lorenz; Acosta, Camilo J; Clemens, John D; Nizami, Shaikh Qamaruddin; Bhutta, Zulfiqar A
  • The percutaneous coronary intervention prior to transcatheter aortic valve implantation (ACTIVATION) trial: study protocol for a randomized controlled trial. (2014) Khawaja, Muhammed Zeeshan; Wang, Duolao; Pocock, Stuart; Redwood, Simon Robert; Thomas, Martyn Rhys
  • Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia. (2008) Kirby, Matthew J; Milligan, Paul J; Conway, David J; Lindsay, Steve W
  • NEWHINTS cluster randomised trial to evaluate the impact on neonatal mortality in rural Ghana of routine home visits to provide a package of essential newborn care interventions in the third trimester of pregnancy and the first week of life: trial protocol. (2010) Kirkwood, Betty R; Manu, Alexander; Tawiah-Agyemang, Charlotte; ten Asbroek, Guus; Gyan, Thomas; Weobong, Benedict; Lewandowski, R Eric; Soremekun, Seyi; Danso, Samuel; Pitt, Catherine; Hanson, Kara; Owusu-Agyei, Seth; Hill, Zelee
  • Feasibility intervention trial of two types of improved cookstoves in three resource-limited settings: study protocol for a randomized controlled trial. (2013) Klasen, Elizabeth; Miranda, J Jaime; Khatry, Subarna; Menya, Diana; Gilman, Robert H; Tielsch, James M; Kennedy, Caitlin; Dreibelbis, Robert; Naithani, Neha; Kimaiyo, Sylvester; Chiang, Marilu; Carter, E Jane; Sherman, Charles B; Breysse, Patrick N; Checkley, William; COCINAS Trial Working Group
  • European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): study protocol for a randomized controlled, non-inferiority trial in eight European countries. (2016) Kleiboer, Annet; Smit, Jan; Bosmans, Judith; Ruwaard, Jeroen; Andersson, Gerhard; Topooco, Naira; Berger, Thomas; Krieger, Tobias; Botella, Cristina; Baños, Rosa; Chevreul, Karine; Araya, Ricardo; Cerga-Pashoja, Arlinda; Cieślak, Roman; Rogala, Anna; Vis, Christiaan; Draisma, Stasja; van Schaik, Anneke; Kemmeren, Lise; Ebert, David; Berking, Matthias; Funk, Burkhardt; Cuijpers, Pim; Riper, Heleen
  • An oral preparation of Lactobacillus acidophilus for the treatment of uncomplicated acute watery diarrhoea in Vietnamese children: study protocol for a multicentre, randomised, placebo-controlled trial. (2013) Kolader, Marion-Eliëtte; Vinh, Ha; Ngoc Tuyet, Pham Thi; Thompson, Corinne; Wolbers, Marcel; Merson, Laura; Campbell, James I; Ngoc Dung, Tran Thi; Manh Tuan, Ha; Vinh Chau, Nguyen Van; Farrar, Jeremy; van Doorn, H Rogier; Baker, Stephen
  • Effects of Study Design and Allocation on participant behaviour--ESDA: study protocol for a randomized controlled trial. (2011) Kypri, Kypros; McCambridge, Jim; Wilson, Amanda; Attia, John; Sheeran, Paschal; Bowe, Steve; Vater, Tina
  • Effects of study design and allocation on self-reported alcohol consumption: randomized trial. (2015) Kypri, Kypros; Wilson, Amanda; Attia, John; Sheeran, Paschal J; McCambridge, Jim
  • Evaluating the effect of innovative motivation and supervision approaches on community health worker performance and retention in Uganda and Mozambique: study protocol for a randomised controlled trial. (2015) Källander, Karin; Strachan, Daniel; Soremekun, Seyi; Hill, Zelee; Lingam, Raghu; Tibenderana, James; Kasteng, Frida; Vassall, Anna; Meek, Sylvia; Kirkwood, Betty
  • Study protocol for a peer-led web-based intervention to promote safe usage of dating applications among young adults: a cluster randomized controlled trial. (2019) Lau, Stephanie Tsz Hei; Choi, Kitty Wai Ying; Chen, Julie; Mak, William Pak-Hing; Yeung, Ho Kong Christopher Au; Tucker, Joseph; Wong, William Chi-Wai
  • TSCQ study: a randomized, controlled, open-label trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Malawi: study protocol for a randomized controlled trial. (2016) Laurens, Matthew B; Mungwira, Randy G; Nyirenda, Osward M; Divala, Titus H; Kanjala, Maxwell; Muwalo, Francis; Mkandawire, Felix A; Tsirizani, Lufina; Nyangulu, Wongani; Mwinjiwa, Edson; Taylor, Terrie E; Mallewa, Jane; Blackwelder, William C; Plowe, Christopher V; Laufer, Miriam K; van Oosterhout, Joep J
  • Clinical research for life-threatening illnesses requiring emergency hospitalisation: a critical interpretive synthesis of qualitative data related to the experience of participants and their caregivers. (2023) Lawrence, David S; Ssali, Agnes; Jarvis, Joseph N; Seeley, Janet
  • AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial. (2018) Lawrence, David S; Youssouf, Nabila; Molloy, Síle F; Alanio, Alexandre; Alufandika, Melanie; Boulware, David R; Boyer-Chammard, Timothée; Chen, Tao; Dromer, Francoise; Hlupeni, Admire; Hope, William; Hosseinipour, Mina C; Kanyama, Cecilia; Lortholary, Oliver; Loyse, Angela; Meya, David B; Mosepele, Mosepele; Muzoora, Conrad; Mwandumba, Henry C; Ndhlovu, Chiratidzo E; Niessen, Louis; Schutz, Charlotte; Stott, Katharine E; Wang, Duolao; Lalloo, David G; Meintjes, Graeme; Jaffar, Shabbar; Harrison, Thomas S; Jarvis, Joseph N
  • Recruiting and consenting into a peripartum trial in an emergency setting: a qualitative study of the experiences and views of women and healthcare professionals. (2016) Lawton, Julia; Snowdon, Claire; Morrow, Susan; Norman, Jane E; Denison, Fiona C; Hallowell, Nina
  • The "ComPAS Trial" combined treatment model for acute malnutrition: study protocol for the economic evaluation. (2018) Lelijveld, Natasha; Bailey, Jeanette; Mayberry, Amy; Trenouth, Lani; N'Diaye, Dieynaba S; Haghparast-Bidgoli, Hassan; Puett, Chloe
  • Impact of a novel molecular TB diagnostic system in patients at high risk of TB mortality in rural South Africa (Uchwepheshe): study protocol for a cluster randomised trial. (2013) Lessells, Richard J; Cooke, Graham S; McGrath, Nuala; Nicol, Mark P; Newell, Marie-Louise; Godfrey-Faussett, Peter
  • The impact of albendazole treatment on the incidence of viral- and bacterial-induced diarrhea in school children in southern Vietnam: study protocol for a randomized controlled trial. (2016) Leung, Jacqueline M; Hong, Chau Tran Thi; Trung, Nghia Ho Dang; Thi, Hoa Nhu; Minh, Chau Nguyen Ngoc; Thi, Thuy Vu; Hong, Dinh Thanh; Man, Dinh Nguyen Huy; Knowles, Sarah CL; Wolbers, Marcel; Hoang, Nhat Le Thanh; Thwaites, Guy; Graham, Andrea L; Baker, Stephen
  • Evaluation of a medication monitor-based treatment strategy for drug-sensitive tuberculosis patients in China: study protocol for a cluster randomised controlled trial. (2018) Lewis, James J; Liu, Xiaoqiu; Zhang, Zhiying; Thomas, Bruce V; Vassall, Anna; Sweeney, Sedona; Caihong, Xu; Dongmei, Hu; Xue, Li; Yongxin, Gao; Huan, Shitong; Shiwen, Jiang; Fielding, Katherine L
  • A comparison of different community models of antiretroviral therapy delivery with the standard of care among stable HIV+ patients: rationale and design of a non-inferiority cluster randomized trial, nested in the HPTN 071 (PopART) study. (2021) Limbada, Mohammed; Bwalya, Chiti; Macleod, David; Floyd, Sian; Schaap, Ab; Situmbeko, Vasty; Hayes, Richard; Fidler, Sarah; Ayles, Helen; HPTN 071 (PopART) Study Team
  • Between-centre differences and treatment effects in randomized controlled trials: a case study in traumatic brain injury. (2011) Lingsma, Hester F; Roozenbeek, Bob; Perel, Pablo; Roberts, Ian; Maas, Andrew IR; Steyerberg, Ewout W
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  • Effect of a nurse-led lifestyle choice and coaching intervention on systolic blood pressure among type 2 diabetic patients with a high atherosclerotic cardiovascular risk: study protocol for a cluster-randomized trial. (2021) Lumu, William; Kibirige, Davis; Wesonga, Ronald; Bahendeka, Silver
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  • Effectiveness of a novel mobile health education intervention (Peek) on spectacle wear among children in India: study protocol for a randomized controlled trial. (2017) Morjaria, Priya; Bastawrous, Andrew; Murthy, Gudlavalleti Venkata Satyanarayana; Evans, Jennifer; Gilbert, Clare
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  • Investigating the non-specific effects of BCG vaccination on the innate immune system in Ugandan neonates: study protocol for a randomised controlled trial. (2015) Prentice, Sarah; Webb, Emily L; Dockrell, Hazel M; Kaleebu, Pontiano; Elliott, Alison M; Cose, Stephen
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  • Digital crowdsourced intervention to promote HIV testing among MSM in China: study protocol for a cluster randomized controlled trial. (2020) Ren, Ci; Tucker, Joseph D; Tang, Weiming; Tao, Xiaorun; Liao, Meizhen; Wang, Guoyong; Jiao, Kedi; Xu, Zece; Zhao, Zhe; Yan, Yu; Lin, Yuxi; Li, Chuanxi; Wang, Lin; Li, Yijun; Kang, Dianmin; Ma, Wei
  • Exploring meaning of participation in a clinical trial in a developing country setting: implications for recruitment. (2011) Reynolds, Joanna; Mangesho, Peter; Vestergaard, Lasse S; Chandler, Clare
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  • Brief intervention for alcohol misuse in people attending sexual health clinics: study protocol for a randomized controlled trial. (2012) Sanatinia, Rahil; Barrett, Barbara; Byford, Sarah; Dean, Madeleine; Green, John; Jones, Rachel; Leurent, Baptiste; Lingford-Hughes, Anne; Sweeting, Michael; Touquet, Robin; Tyrer, Peter; Ward, Helen; Crawford, Mike J
  • Comprehensive Anaemia Programme and Personalized Therapies (CAPPT): protocol for a cluster-randomised controlled trial testing the effect women's groups, home counselling and iron supplementation on haemoglobin in pregnancy in southern Nepal. (2022) Saville, Naomi M; Kharel, Chandani; Morrison, Joanna; Harris-Fry, Helen; James, Philip; Copas, Andrew; Giri, Santosh; Arjyal, Abriti; Beard, B James; Haghparast-Bidgoli, Hassan; Skordis, Jolene; Richter, Adam; Baral, Sushil; Hillman, Sara
  • Community-based scheduled screening and treatment of malaria in pregnancy for improved maternal and infant health in The Gambia, Burkina Faso and Benin: study protocol for a randomized controlled trial. (2014) Scott, Susana; Mens, Petra F; Tinto, Halidou; Nahum, Alain; Ruizendaal, Esmée; Pagnoni, Franco; Grietens, Koen Peeters; Kendall, Lindsay; Bojang, Kalifa; Schallig, Henk; D'Alessandro, Umberto
  • Baseline characteristics, analysis plan and report on feasibility for the Prevention Of Decline in Cognition After Stroke Trial (PODCAST). (2015) Scutt, Polly; Blackburn, Dan; Krishnan, Kailash; Ballard, Clive; Burns, Alistair; Ford, Gary A; Mant, Jonathan; Passmore, Peter; Pocock, Stuart; Reckless, John; Sprigg, Nikola; Stewart, Rob; Wardlaw, Joanna M; Bath, Philip M
  • The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury. (2009) Shakur, Haleema; Andrews, Peter; Asser, Toomas; Balica, Laura; Boeriu, Cristian; Quintero, Juan Diego Ciro; Dewan, Yashbir; Druwé, Patrick; Fletcher, Olivia; Frost, Chris; Hartzenberg, Bennie; Mantilla, Jorge Mejia; Murillo-Cabezas, Francisco; Pachl, Jan; Ravi, Ramalingam R; Rätsep, Indrek; Sampaio, Cristina; Singh, Manmohan; Svoboda, Petr; Roberts, Ian
  • The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial. (2010) Shakur, Haleema; Elbourne, Diana; Gülmezoglu, Metin; Alfirevic, Zarko; Ronsmans, Carine; Allen, Elizabeth; Roberts, Ian
  • The effect of tranexamic acid on the risk of death and hysterectomy in women with post-partum haemorrhage: statistical analysis plan for the WOMAN trial. (2016) Shakur, Haleema; Roberts, Ian; Edwards, Philip; Elbourne, Diana; Alfirevic, Zarko; Ronsmans, Carine
  • A quasi-randomised controlled trial of online distribution of home-based hepatitis C self-testing for key populations in Malaysia: a study protocol. (2022) Shilton, Sonjelle; Sem, Xiaohui; Chan, Huan-Keat; Chung, Han Yang; Karunanithy, Anu; Markby, Jessica; Chan, Po-Lin; Luhmann, Niklas; Johnson, Cheryl; Nabeta, Pamela; Nasir, Nazrila Hairizan Bt; Ongarello, Stefano; Reipold, Elena Ivanova; Hassan, Muhammad Radzi Abu
  • Effectiveness of low-dose theophylline for the management of biomass-associated COPD (LODOT-BCOPD): study protocol for a randomized controlled trial. (2021) Siddharthan, Trishul; Pollard, Suzanne L; Jackson, Peter; Robertson, Nicole M; Wosu, Adaeze C; Rahman, Nihaal; Padalkar, Roma; Sekitoleko, Isaac; Namazzi, Esther; Alupo, Patricia; Hurst, John R; Kalyesubula, Robert; Dowdy, David; Wise, Robert; Barnes, Peter J; Checkley, William; Kirenga, Bruce
  • The effectiveness and cost-effectiveness of the peer-delivered Thinking Healthy Programme for perinatal depression in Pakistan and India: the SHARE study protocol for randomised controlled trials. (2015) Sikander, Siham; Lazarus, Anisha; Bangash, Omer; Fuhr, Daniela C; Weobong, Benedict; Krishna, Revathi N; Ahmad, Ikhlaq; Weiss, Helen A; Price, LeShawndra; Rahman, Atif; Patel, Vikram
  • Response to: The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury. (2009) Simmon, Vincent F ['material/summary:fileicon_text/html' not defined]
  • Assessing loss to follow-up in the MObile Technology for Improved Family Planning (MOTIF) randomised controlled trial. (2017) Smith, Chris; Jarvis, Christopher; Free, Caroline
  • MObile Technology for Improved Family Planning: update to randomised controlled trial protocol. (2014) Smith, Chris; Ngo, Thoai D; Edwards, Phil; Free, Caroline
  • MObile Technology for Improved Family Planning Services (MOTIF): study protocol for a randomised controlled trial. (2013) Smith, Chris; Vannak, Uk; Sokhey, Ly; Ngo, Thoai D; Gold, Judy; Khut, Khemrin; Edwards, Phil; Rathavy, Tung; Free, Caroline
  • Qualitative and mixed methods research in trials. (2015) Snowdon, Claire
  • Financial considerations in the conduct of multi-centre randomised controlled trials: evidence from a qualitative study. (2006) Snowdon, Claire; Elbourne, Diana R; Garcia, Jo; Campbell, Marion K; Entwistle, Vikki A; Francis, David; Grant, Adrian M; Knight, Rosemary C; McDonald, Alison M; Roberts, Ian
  • The BRACELET Study: surveys of mortality in UK neonatal and paediatric intensive care trials. (2010) Snowdon, Claire; Harvey, Sheila E; Brocklehurst, Peter; Tasker, Robert C; Platt, Martin P Ward; Allen, Elizabeth; Elbourne, Diana
  • Tailored, psychological intervention for anxiety or depression in people with chronic obstructive pulmonary disease (COPD), TANDEM (Tailored intervention for ANxiety and DEpression Management in COPD): protocol for a randomised controlled trial. (2020) Sohanpal, Ratna; Pinnock, Hilary; Steed, Liz; Heslop Marshall, Karen; Chan, Claire; Kelly, Moira; Priebe, Stefan; Roberts, C Michael; Singh, Sally; Smuk, Melanie; Saqi-Waseem, Sarah; Healey, Andy; Underwood, Martin; White, Patrick; Warburton, Chris; Taylor, Stephanie JC; TANDEM Investigators
  • Models and impact of patient and public involvement in studies carried out by the Medical Research Council Clinical Trials Unit at University College London: findings from ten case studies. (2016) South, Annabelle; Hanley, Bec; Gafos, Mitzy; Cromarty, Ben; Stephens, Richard; Sturgeon, Kate; Scott, Karen; Cragg, William J; Tweed, Conor D; Teera, Jacqueline; Vale, Claire L
  • LLIN Evaluation in Uganda Project (LLINEUP) - Impact of long-lasting insecticidal nets with, and without, piperonyl butoxide on malaria indicators in Uganda: study protocol for a cluster-randomised trial. (2019) Staedke, Sarah G; Kamya, Moses R; Dorsey, Grant; Maiteki-Sebuguzi, Catherine; Gonahasa, Samuel; Yeka, Adoke; Lynd, Amy; Opigo, Jimmy; Hemingway, Janet; Donnelly, Martin J
  • Reducing the environmental impact of trials: a comparison of the carbon footprint of the CRASH-1 and CRASH-2 clinical trials. (2011) Subaiya, Saleena; Hogg, Euan; Roberts, Ian
  • A framework for handling missing accelerometer outcome data in trials. (2021) Tackney, Mia S; Cook, Derek G; Stahl, Daniel; Ismail, Khalida; Williamson, Elizabeth; Carpenter, James
  • A comparison of covariate adjustment approaches under model misspecification in individually randomized trials. (2023) Tackney, Mia S; Morris, Tim; White, Ian; Leyrat, Clemence; Diaz-Ordaz, Karla; Williamson, Elizabeth
  • Effect of community active case-finding strategies for detection of tuberculosis in Cambodia: study protocol for a pragmatic cluster randomized controlled trial. (2020) Teo, Alvin Kuo Jing; Prem, Kiesha; Evdokimov, Konstantin; Ork, Chetra; Eng, Sothearith; Tuot, Sovannary; Chry, Monyrath; Mao, Tan Eang; Hsu, Li Yang; Yi, Siyan
  • Using discrete choice experiments to inform the design of complex interventions. (2019) Terris-Prestholt, Fern; Neke, Nyasule; Grund, Jonathan M; Plotkin, Marya; Kuringe, Evodius; Osaki, Haika; Ong, Jason J; Tucker, Joseph D; Mshana, Gerry; Mahler, Hally; Weiss, Helen A; Wambura, Mwita; VMMC study team
  • When enough is enough: how the decision was made to stop the FEAST trial: data and safety monitoring in an African trial of Fluid Expansion As Supportive Therapy (FEAST) for critically ill children. (2013) Todd, Jim; Heyderman, Robert S; Musoke, Philippa; Peto, Tim
  • An effectiveness study of an integrated, community-based package for maternal, newborn, child and HIV care in South Africa: study protocol for a randomized controlled trial. (2011) Tomlinson, Mark; Doherty, Tanya; Jackson, Debra; Lawn, Joy E; Ijumba, Petrida; Colvin, Mark; Nkonki, Lungiswa; Daviaud, Emmanuelle; Goga, Ameena; Sanders, David; Lombard, Carl; Persson, Lars Åke; Ndaba, Thoko; Snetro, Gail; Chopra, Mickey
  • Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform. (2015) Treweek, Shaun; Altman, Doug G; Bower, Peter; Campbell, Marion; Chalmers, Iain; Cotton, Seonaidh; Craig, Peter; Crosby, David; Davidson, Peter; Devane, Declan; Duley, Lelia; Dunn, Janet; Elbourne, Diana; Farrell, Barbara; Gamble, Carrol; Gillies, Katie; Hood, Kerry; Lang, Trudie; Littleford, Roberta; Loudon, Kirsty; McDonald, Alison; McPherson, Gladys; Nelson, Annmarie; Norrie, John; Ramsay, Craig; Sandercock, Peter; Shanahan, Daniel R; Summerskill, William; Sydes, Matt; Williamson, Paula; Clarke, Mike
  • Protocol for a randomized controlled trial: peer-to-peer Group Problem Management Plus (PM+) for adult Syrian refugees in Turkey. (2020) Uygun, Ersin; Ilkkursun, Zeynep; Sijbrandij, Marit; Aker, A Tamer; Bryant, Richard; Cuijpers, Pim; Fuhr, Daniela C; de Graaff, Anne M; de Jong, Joop; McDaid, David; Morina, Naser; Park, A-La; Roberts, Bayard; Ventevogel, Peter; Yurtbakan, Taylan; Acarturk, Ceren; STRENGHTS consortium
  • When participants get involved: reconsidering patient and public involvement in clinical trials at the MRC Clinical Trials Unit at UCL. (2018) Vale, Claire L; Cragg, William J; Cromarty, Ben; Hanley, Bec; South, Annabelle; Stephens, Richard; Sturgeon, Kate; Gafos, Mitzy
  • Information on blinding in registered records of clinical trials. (2012) Viergever, Roderik F; Ghersi, Davina
  • The HOME Study: study protocol for a randomised controlled trial comparing the addition of Proactive Psychological Medicine to usual care, with usual care alone, on the time spent in hospital by older acute hospital inpatients. (2019) Walker, Jane; Burke, Katy; Toynbee, Mark; van Niekerk, Maike; Frost, Chris; Magill, Nicholas; Walker, Simon; Sculpher, Mark; White, Ian R; Sharpe, Michael
  • Are realist randomised controlled trials possible? A reflection on the INCLUSIVE evaluation of a whole-school, bullying-prevention intervention. (2022) Warren, Emily A; Melendez-Torres, GJ; Bonell, Chris
  • Using qualitative research to explore intervention mechanisms: findings from the trial of the Learning Together whole-school health intervention. (2020) Warren, Emily; Melendez-Torres, GJ; Viner, Russell; Bonell, Chris
  • Development of a composite outcome score for a complex intervention - measuring the impact of Community Health Workers. (2015) Watt, Hilary; Harris, Matthew; Noyes, Jane; Whitaker, Rhiannon; Hoare, Zoe; Edwards, Rhiannon Tudor; Haines, Andy
  • The praziquantel in preschoolers (PIP) trial: study protocol for a phase II PK/PD-driven randomised controlled trial of praziquantel in children under 4 years of age. (2021) Webb, Emily L; Edielu, Andrew; Wu, Hannah W; Kabatereine, Narcis B; Tukahebwa, Edridah M; Mubangizi, Alfred; Adriko, Moses; Elliott, Alison M; Hope, William W; Mawa, Patrice A; Friedman, Jennifer F; Bustinduy, Amaya L
  • Lovastatin for adult patients with dengue: protocol for a randomised controlled trial. (2012) Whitehorn, James; Van Vinh Chau, Nguyen; Truong, Nguyen Thanh; Tai, Luong Thi Hue; Van Hao, Nguyen; Hien, Tran Tinh; Wolbers, Marcel; Merson, Laura; Dung, Nguyen Thi Phuong; Peeling, Rosanna; Simmons, Cameron; Wills, Bridget; Farrar, Jeremy
  • Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study. (2018) Whitham, Diane; Turzanski, Julie; Bradshaw, Lucy; Clarke, Mike; Culliford, Lucy; Duley, Lelia; Shaw, Lisa; Skea, Zoe; Treweek, Shaun P; Walker, Kate; Williamson, Paula R; Montgomery, Alan A; Site Performance Metrics for Multicentre Randomised Trials Colla
  • A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury. (2022) Williams, Jack; Ker, Katharine; Roberts, Ian; Shakur-Still, Haleema; Miners, Alec picture_as_pdf
  • A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury. (2022) Williams, Jack; Ker, Katharine; Roberts, Ian; Shakur-Still, Haleema; Miners, Alec picture_as_pdf
  • A cost-effectiveness analysis of provider interventions to improve health worker practice in providing treatment for uncomplicated malaria in Cameroon: a study protocol for a randomized controlled trial. (2012) Wiseman, Virginia; Mangham, Lindsay J; Cundill, Bonnie; Achonduh, Olivia A; Nji, Akindeh Mbuh; Njei, Abanda Ngu; Chandler, Clare; Mbacham, Wilfred F
  • A cost-effectiveness analysis of provider and community interventions to improve the treatment of uncomplicated malaria in Nigeria: study protocol for a randomized controlled trial. (2012) Wiseman, Virginia; Ogochukwu, Ezeoke; Emmanuel, Nwala; Lindsay J, Mangham; Bonnie, Cundill; Jane, Enemuo; Eloka, Uchegbu; Benjamin, Uzochukwu; Obinna, Onwujekwe
  • The immune response to 6-monthly versus annual standard dose inactivated trivalent influenza vaccination in older people: study protocol for a randomised clinical trial. (2017) Young, Barnaby; Sadarangani, Sapna; Yew, Haur Sen; Yung, Chee Fu; Leo, Yee Sin; Chen, Mark I-Cheng; Wilder-Smith, Annelies
  • The impact of long-lasting microbial larvicides in reducing malaria transmission and clinical malaria incidence: study protocol for a cluster randomized controlled trial. (2016) Zhou, Guofa; Wiseman, Virginia; Atieli, Harrysone E; Lee, Ming-Chieh; Githeko, Andrew K; Yan, Guiyun
  • Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT. (2007) Ziebland, Sue; Featherstone, Katie; Snowdon, Claire; Barker, Karen; Frost, Helen; Fairbank, Jeremy
    • Conference or Workshop Item
  • The quality of reporting of pilot and feasibility cluster randomised trials: a systematic review. (2015) Coleman, Claire; Leyrat, Clemence; Eldridge, Sandra
  • Assessing sensitivity to assumptions in mixed effects analyses of stepped-wedge trials. (2015) Davey, C; Thompson, JA
  • Using evidence from observational healthcare data to inform a trial design. (2013) Hansen, CH; Murray, G; Sharpe, M
  • An integrated approach to the development of a Bayesian response-adaptive dose-finding study using sas and winbugs. (2013) Hansen, CH; Weir, C; Warner, P; Critchley, H
  • Considering the design effect for the stepped wedge trial: what can it tell us? (2015) Thompson, J; Fielding, K; Hargreaves, J; Copas, A
  • The optimal design of the stepped wedge trial and a comparison to other trial designs. (2017) Thompson, JA; Fielding, K; Hargreaves, J; Copas, A
  • Implications of Misspecifed Mixed Effect Models in Stepped Wedge Trial Analysis: How Wrong Can It Be? (2016) Thompson, JA; Fielding, KL; Davey, C; Aiken, AM; Hargreaves, JR; Hayes, RJ
  • Randomised Evaluations of Accepted Choices in Treatment (REACT) trials: large-scale pragmatic trials within databases of routinely collected electronic healthcare records. (2011) van Staa, TP; Goldacre, B; Gulliford, M; Cassell, J; Pirmohamed, M; Taweel, A; Delaney, B; Smeeth, L
    • Other
  • Erratum to: 'Models and impact of patient and public involvement in studies carried out by the Medical Research Council Clinical Trials Unit at University College London: findings from ten case studies'. (2016) South, A; Hanley, B; Gafos, M; Cromarty, B; Stephens, R; Sturgeon, K; Scott, K; Cragg, WJ; Tweed, CD; Teera, J; Vale, CL