Items where the Publication is Infection and immunity
Number of items: 133.
2017
Use of Proteins Identified through a Functional Genomic Screen To Develop a Protein Subunit Vaccine That Provides Significant Protection against Virulent Streptococcus suis in Pigs. (2017)
Brockmeier, Susan L; Loving, Crystal L; Nicholson, Tracy L; Wang, Jinhong; Peters, Sarah E; Weinert, Lucy; Chaudhuri, Roy; Seilly, David J; Langford, Paul R; Rycroft, Andrew; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W
Host Resistance to Plasmodium-Induced Acute Immune Pathology Is Regulated by Interleukin-10 Receptor Signaling. (2017)
Claser, Carla; De Souza, J Brian; Thorburn, Samuel G; Grau, Georges Emile; Riley, Eleanor M; Rénia, Laurent; Hafalla, Julius CR
Comparison of Salmonella enterica Serovars Typhi and Typhimurium Reveals Typhoidal Serovar-Specific Responses to Bile. (2017)
Johnson, Rebecca; Ravenhall, Matt; Pickard, Derek; Dougan, Gordon; Byrne, Alexander; Frankel, Gad
The Enterohemorrhagic Escherichia coli Effector EspW Triggers Actin Remodeling in a Rac1-Dependent Manner. (2017)
Sandu, Pamela; Crepin, Valerie F; Drechsler, Hauke; McAinsh, Andrew D; Frankel, Gad; Berger, Cedric N
2016
Model of Host-Pathogen Interaction Dynamics Links In Vivo Optical Imaging and Immune Responses. (2016)
Ale, Angelique; Crepin, Valerie F; Collins, James W; Constantinou, Nicholas; Habibzay, Maryam; Babtie, Ann C; Frankel, Gad; Stumpf, Michael PH
Transcriptional Profiling of Mycobacterium tuberculosis Exposed to In Vitro Lysosomal Stress. (2016)
Lin, Wenwei; de Sessions, Paola Florez; Teoh, Garrett Hor Keong; Mohamed, Ahmad Naim Nazri; Zhu, Yuan O; Koh, Vanessa Hui Qi; Ang, Michelle Lay Teng; Dedon, Peter C; Hibberd, Martin Lloyd; Alonso, Sylvie
The Type III Secretion System Effector SeoC of Salmonella enterica subsp. salamae and S. enterica subsp. arizonae ADP-Ribosylates Src and Inhibits Opsonophagocytosis. (2016)
Pollard, Dominic J; Young, Joanna C; Covarelli, Valentina; Herrera-León, Silvia; Connor, Thomas R; Fookes, Maria; Walker, Danielle; Echeita, Aurora; Thomson, Nicholas R; Berger, Cedric N; Frankel, Gad
2015
Variation in Plasmodium falciparum erythrocyte invasion phenotypes and merozoite ligand gene expression across different populations in areas of malaria endemicity. (2015)
Bowyer, Paul W; Stewart, Lindsay B; Aspeling-Jones, Harvey; Mensah-Brown, Henrietta E; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Awandare, Gordon A; Conway, David J
Tir Triggers Expression of CXCL1 in Enterocytes and Neutrophil Recruitment during Citrobacter rodentium Infection. (2015)
Crepin, Valerie F; Habibzay, Maryam; Glegola-Madejska, Izabela; Guenot, Marianne; Collins, James W; Frankel, Gad
Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells. (2015)
Guenot, Marianne; Loizon, Séverine; Howard, Jennifer; Costa, Giulia; Baker, David A; Mohabeer, Shaneel Y; Troye-Blomberg, Marita; Moreau, Jean-François; Déchanet-Merville, Julie; Mercereau-Puijalon, Odile; Mamani-Matsuda, Maria; Behr, Charlotte
Pancreatic amylase is an environmental signal for regulation of biofilm formation and host interaction in Campylobacter jejuni. (2015)
Jowiya, Waheed; Brunner, Katja; Abouelhadid, Sherif; Hussain, Haitham A; Nair, Sean P; Sadiq, Sohaib; Williams, Lisa K; Trantham, Emma K; Stephenson, Holly; Wren, Brendan W; Bajaj-Elliott, Mona; Cogan, Tristan A; Laws, Andrew P; Wade, Jim; Dorrell, Nick; Allan, Elaine
The Genotoxin Colibactin Is a Determinant of Virulence in Escherichia coli K1 Experimental Neonatal Systemic Infection. (2015)
McCarthy, Alex J; Martin, Patricia; Cloup, Emilie; Stabler, Richard A; Oswald, Eric; Taylor, Peter W
description
Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei. (2015)
Moule, Madeleine G; Spink, Natasha; Willcocks, Sam; Lim, Jiali; Guerra-Assunção, José Afonso; Cia, Felipe; Champion, Olivia L; Senior, Nicola J; Atkins, Helen S; Clark, Taane; Bancroft, Gregory J; Cuccui, Jon; Wren, Brendan W
Pneumococcal 6-Phospho-β-Glucosidase (BglA3) Is Involved in Virulence and Nutrient Metabolism. (2015)
Terra, Vanessa Sofia; Zhi, Xiangyun; Kahya, Hasan F; Andrew, Peter W; Yesilkaya, Hasan
2014
Host immunity to Clostridium difficile PCR ribotype 017 strains. (2014)
Jafari, Nazila V; Songane, Mario; Stabler, Richard A; Elawad, Mamoun; Wren, Brendan W; Allan, Elaine; Bajaj-Elliott, Mona
Genome-wide evaluation of the interplay between Caenorhabditis elegans and Yersinia pseudotuberculosis during in vivo biofilm formation. (2014)
Joshua, George WP; Atkinson, Steve; Goldstone, Robert J; Patrick, Hannah L; Stabler, Richard A; Purves, Joanne; Cámara, Miguel; Williams, Paul; Wren, Brendan W
2013
Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli. (2013)
Birchenough, George MH; Johansson, Malin EV; Stabler, Richard A; Dalgakiran, Fatma; Hansson, Gunnar C; Wren, Brendan W; Luzio, J Paul; Taylor, Peter W
Modulation of the immune and inflammatory responses by Plasmodium falciparum schizont extracts: role of myeloid dendritic cells in effector and regulatory functions of CD4+ lymphocytes. (2013)
Clemente, Ann Maria; Fadigati, Giulia; Caporale, Roberto; Marchese, Damiano G; Castronovo, Giuseppe; Sannella, Anna Rosa; Severini, Carlo; Verra, Federica; Garaci, Enrico; Cozzolino, Federico; Torcia, Maria Gabriella
IL-27 receptor signaling regulates memory CD4+ T cell populations and suppresses rapid inflammatory responses during secondary malaria infection. (2013)
Gwyer Findlay, Emily; Villegas-Mendez, Ana; O'Regan, Noelle; de Souza, J Brian; Grady, Lisa-Marie; Saris, Christiaan J; Riley, Eleanor M; Couper, Kevin N
Characteristic age distribution of Plasmodium vivax infections after malaria elimination on Aneityum Island, Vanuatu. (2013)
Kaneko, Akira; Chaves, Luis F; Taleo, George; Kalkoa, Morris; Isozumi, Rie; Wickremasinghe, Renu; Perlmann, Hedvig; Takeo, Satoru; Tsuboi, Takafumi; Tachibana, Shin-ichiro; Kimura, Masatsugu; Björkman, Anders; Troye-Blomberg, Marita; Tanabe, Kazuyuki; Drakeley, Chris
Analysis of antibodies to newly described Plasmodium falciparum merozoite antigens supports MSPDBL2 as a predicted target of naturally acquired immunity. (2013)
Tetteh, Kevin KA; Osier, Faith HA; Salanti, Ali; Kamuyu, Gathoni; Drought, Laura; Failly, Marilyne; Martin, Christophe; Marsh, Kevin; Conway, David J
2012
Susceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9. (2012)
Carroll, Scott F; Lafferty, Erin I; Flaczyk, Adam; Fujiwara, T Mary; Homer, Robert; Morgan, Kenneth; Loredo-Osti, JC; Qureshi, Salman T
Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region. (2012)
Cuccui, Jon; Milne, Timothy S; Harmer, Nicholas; George, Alison J; Harding, Sarah V; Dean, Rachel E; Scott, Andrew E; Sarkar-Tyson, Mitali; Wren, Brendan W; Titball, Richard W; Prior, Joann L
The Clostridium difficile spo0A gene is a persistence and transmission factor. (2012)
Deakin, Laura J; Clare, Simon; Fagan, Robert P; Dawson, Lisa F; Pickard, Derek J; West, Michael R; Wren, Brendan W; Fairweather, Neil F; Dougan, Gordon; Lawley, Trevor D
Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. (2012)
Elmi, Abdi; Watson, Eleanor; Sandu, Pamela; Gundogdu, Ozan; Mills, Dominic C; Inglis, Neil F; Manson, Erin; Imrie, Lisa; Bajaj-Elliott, Mona; Wren, Brendan W; Smith, David GE; Dorrell, Nick
Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment. (2012)
Mills, Dominic C; Gundogdu, Ozan; Elmi, Abdi; Bajaj-Elliott, Mona; Taylor, Peter W; Wren, Brendan W; Dorrell, Nick
Role of RelA and SpoT in Burkholderia pseudomallei virulence and immunity. (2012)
Müller, Claudia M; Conejero, Laura; Spink, Natasha; Wand, Matthew E; Bancroft, Gregory J; Titball, Richard W
Neutrophil extracellular traps exhibit antibacterial activity against burkholderia pseudomallei and are influenced by bacterial and host factors. (2012)
Riyapa, Donporn; Buddhisa, Surachat; Korbsrisate, Sunee; Cuccui, Jon; Wren, Brendan W; Stevens, Mark P; Ato, Manabu; Lertmemongkolchai, Ganjana
2011
Active trachoma is associated with increased conjunctival expression of IL17A and profibrotic cytokines. (2011)
Burton, Matthew J; Ramadhani, Athumani; Weiss, Helen A; Hu, Victor; Massae, Patrick; Burr, Sarah E; Shangali, Wahida; Holland, Martin J; Mabey, David CW; Bailey, Robin L
Experimental cerebral malaria develops independently of caspase recruitment domain-containing protein 9 signaling. (2011)
Hafalla, Julius Clemence R; Burgold, Jan; Dorhoi, Anca; Gross, Olaf; Ruland, Jürgen; Kaufmann, Stefan HE; Matuschewski, Kai
Innate immune responses and modified extracellular matrix regulation characterize bacterial infection and cellular/connective tissue changes in scarring trachoma. (2011)
Hu, Victor H; Weiss, Helen A; Ramadhani, Athumani M; Tolbert, Sonda B; Massae, Patrick; Mabey, David CW; Holland, Martin J; Bailey, Robin L; Burton, Matthew J
Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malaria. (2011)
Kordes, Maximilian; Matuschewski, Kai; Hafalla, Julius Clemence R
Naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs48/45 and Pfs230 in an area of seasonal transmission. (2011)
Ouédraogo, André Lin; Roeffen, Will; Luty, Adrian JF; de Vlas, Sake J; Nebie, Issa; Ilboudo-Sanogo, Edith; Cuzin-Ouattara, Nadine; Teleen, Karina; Tiono, Alfred B; Sirima, Sodiomon Bienvenu; Verhave, Jan-Peter; Bousema, Teun; Sauerwein, Robert
Global identification of multiple substrates for Plasmodium falciparum SUB1, an essential malarial processing protease. (2011)
Silmon de Monerri, Natalie C; Flynn, Helen R; Campos, Marta G; Hackett, Fiona; Koussis, Konstantinos; Withers-Martinez, Chrislaine; Skehel, J Mark; Blackman, Michael J
2010
Bacterial guanine nucleotide exchange factors SopE-like and WxxxE effectors. (2010)
Bulgin, Richard; Raymond, Benoit; Garnett, James A; Frankel, Gad; Crepin, Valerie F; Berger, Cedric N; Arbeloa, Ana
Conjunctival transcriptome in scarring trachoma. (2010)
Burton, Matthew J; Rajak, Saul N; Bauer, Julien; Weiss, Helen A; Tolbert, Sonda B; Shoo, Alice; Habtamu, Esmail; Manjurano, Alphaxard; Emerson, Paul M; Mabey, David CW; Holland, Martin J; Bailey, Robin L
Chronic intestinal helminth infections are associated with immune hyporesponsiveness and induction of a regulatory network. (2010)
Figueiredo, Camila Alexandrina; Barreto, Mauricio L; Rodrigues, Laura C; Cooper, Philip J; Silva, Nívea Bispo; Amorim, Leila D; Alcantara-Neves, Neuza Maria
Phylogenetic analysis of Chlamydia trachomatis Tarp and correlation with clinical phenotype. (2010)
Lutter, Erika I; Bonner, Christine; Holland, Martin J; Suchland, Robert J; Stamm, Walter E; Jewett, Travis J; McClarty, Grant; Hackstadt, Ted
Human conjunctival transcriptome analysis reveals the prominence of innate defense in Chlamydia trachomatis infection. (2010)
Natividad, Angels; Freeman, Tom C; Jeffries, David; Burton, Matthew J; Mabey, David CW; Bailey, Robin L; Holland, Martin J
Allelic diversity and naturally acquired allele-specific antibody responses to Plasmodium falciparum apical membrane antigen 1 in Kenya. (2010)
Osier, Faith HA; Weedall, Gareth D; Verra, Federica; Murungi, Linda; Tetteh, Kevin KA; Bull, Pete; Faber, Bart W; Remarque, Ed; Thomas, Alan; Marsh, Kevin; Conway, David J
Characterization of novel beta-galactosidase activity that contributes to glycoprotein degradation and virulence in Streptococcus pneumoniae. (2010)
Terra, Vanessa S; Homer, Karen A; Rao, Susmitha G; Andrew, Peter W; Yesilkaya, Hasan
Burkholderia pseudomallei proteins presented by monocyte-derived dendritic cells stimulate human memory T cells in vitro. (2010)
Tippayawat, Patcharaporn; Pinsiri, Maneerat; Rinchai, Darawan; Riyapa, Donporn; Romphruk, Amornrat; Gan, Yunn-Hwen; Houghton, Raymond L; Felgner, Philip L; Titball, Richard W; Stevens, Mark P; Galyov, Edouard E; Bancroft, Gregory J; Lertmemongkolchai, Ganjana
Severity of Staphylococcus aureus infection of the skin is associated with inducibility of human beta-defensin 3 but not human beta-defensin 2. (2010)
Zanger, Philipp; Holzer, Johannes; Schleucher, Regina; Scherbaum, Helmut; Schittek, Birgit; Gabrysch, Sabine
Neutralization of malaria glycosylphosphatidylinositol in vitro by serum IgG from malaria-exposed individuals. (2010)
de Souza, J Brian; Runglall, Manohursingh; Corran, Patrick H; Okell, Lucy C; Kumar, Sanjeev; Gowda, D Channe; Couper, Kevin N; Riley, Eleanor M
2009
Beta2-microglobulin-dependent bacterial clearance and survival during murine Klebsiella pneumoniae bacteremia. (2009)
Cogen, Anna L; Moore, Thomas A
Campylobacter jejuni cocultured with epithelial cells reduces surface capsular polysaccharide expression. (2009)
Corcionivoschi, N; Clyne, M; Lyons, A; Elmi, A; Gundogdu, O; Wren, BW; Dorrell, N; Karlyshev, AV; Bourke, B
Modelling of infection by enteropathogenic Escherichia coli strains in lineages 2 and 4 ex vivo and in vivo by using Citrobacter rodentium expressing TccP. (2009)
Girard, Francis; Crepin, Valérie F; Frankel, Gad
Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. (2009)
Howard, Sarah L; Jagannathan, Aparna; Soo, Evelyn C; Hui, Joseph PM; Aubry, Annie J; Ahmed, Imran; Karlyshev, Andrey; Kelly, John F; Jones, Michael A; Stevens, Mark P; Logan, Susan M; Wren, Brendan W
Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. (2009)
Lawley, Trevor D; Clare, Simon; Walker, Alan W; Goulding, David; Stabler, Richard A; Croucher, Nicholas; Mastroeni, Piero; Scott, Paul; Raisen, Claire; Mottram, Lynda; Fairweather, Neil F; Wren, Brendan W; Parkhill, Julian; Dougan, Gordon
Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies. (2009)
Lazarou, Maria; Guevara Patiño, José A; Jennings, Richard M; McIntosh, Richard S; Shi, Jianguo; Howell, Steven; Cullen, Eilish; Jones, Tarran; Adame-Gallegos, Jaime R; Chappel, Jonathan A; McBride, Jana S; Blackman, Michael J; Holder, Anthony A; Pleass, Richard J
Polymorphisms in erythrocyte binding antigens 140 and 181 affect function and binding but not receptor specificity in Plasmodium falciparum. (2009)
Maier, Alexander G; Baum, Jake; Smith, Brian; Conway, David J; Cowman, Alan F
Pyruvate formate lyase is required for pneumococcal fermentative metabolism and virulence. (2009)
Yesilkaya, Hasan; Spissu, Francesca; Carvalho, Sandra M; Terra, Vanessa S; Homer, Karen A; Benisty, Rachel; Porat, Nurith; Neves, Ana R; Andrew, Peter W
2008
Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific. (2008)
Akpogheneta, Onome J; Duah, Nancy O; Tetteh, Kevin KA; Dunyo, Samuel; Lanar, David E; Pinder, Margaret; Conway, David J
Chronic intestinal nematode infection exacerbates experimental Schistosoma mansoni infection. (2008)
Bickle, Quentin D; Solum, Julie; Helmby, Helena
The p50 subunit of NF-kappaB is critical for in vivo clearance of the noninvasive enteric pathogen Citrobacter rodentium. (2008)
Dennis, Alison; Kudo, Takahiro; Kruidenier, Laurens; Girard, Francis; Crepin, Valerie F; MacDonald, Thomas T; Frankel, Gad; Wiles, Siouxsie
Role of NleH, a type III secreted effector from attaching and effacing pathogens, in colonization of the bovine, ovine, and murine gut. (2008)
Hemrajani, Cordula; Marches, Olivier; Wiles, Siouxsie; Girard, Francis; Dennis, Alison; Dziva, Francis; Best, Angus; Phillips, Alan D; Berger, Cedric N; Mousnier, Aurelie; Crepin, Valerie F; Kruidenier, Laurens; Woodward, Martin J; Stevens, Mark P; La Ragione, Roberto M; MacDonald, Thomas T; Frankel, Gad
Bystander macrophage apoptosis after Mycobacterium tuberculosis H37Ra infection. (2008)
Kelly, Deirdre M; ten Bokum, Annemieke MC; O'Leary, Seonadh M; O'Sullivan, Mary P; Keane, Joseph
Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria. (2008)
Osier, Faith HA; Fegan, Gregory; Polley, Spencer D; Murungi, Linda; Verra, Federica; Tetteh, Kevin KA; Lowe, Brett; Mwangi, Tabitha; Bull, Peter C; Thomas, Alan W; Cavanagh, David R; McBride, Jana S; Lanar, David E; Mackinnon, Margaret J; Conway, David J; Marsh, Kevin
Vibrio vulnificus biotype 2 serovar E gne but not galE is essential for lipopolysaccharide biosynthesis and virulence. (2008)
Valiente, Esmeralda; Jiménez, Natalia; Merino, Susana; Tomás, Juan M; Amaro, Carmen
2007
Strain-dependent variation in Mycobacterium bovis BCG-induced human T-cell activation and gamma interferon production in vitro. (2007)
Aguirre-Blanco, Ana M; Lukey, Pauline T; Cliff, Jacqueline M; Dockrell, Hazel M
Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia. (2007)
Couper, Kevin N; Blount, Daniel G; Hafalla, Julius CR; van Rooijen, Nico; de Souza, J Brian; Riley, Eleanor M
Invasion pathways and malaria severity in Kenyan Plasmodium falciparum clinical isolates. (2007)
Deans, Anne-Marie; Nery, Susana; Conway, David J; Kai, Oscar; Marsh, Kevin; Rowe, J Alexandra
Identification of a LolC homologue in Burkholderia pseudomallei, a novel protective antigen for melioidosis. (2007)
Harland, David N; Chu, Karen; Haque, Ashraful; Nelson, Michelle; Walker, Nicola J; Sarkar-Tyson, Mitali; Atkins, Timothy P; Moore, Benjamin; Brown, Katherine A; Bancroft, Gregory; Titball, Richard W; Atkins, Helen S
Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. (2007)
Lin, May Young; Geluk, Annemieke; Smith, Steven G; Stewart, Amanda L; Friggen, Annemieke H; Franken, Kees LMC; Verduyn, Marleen JC; van Meijgaarden, Krista E; Voskuil, Martin I; Dockrell, Hazel M; Huygen, Kris; Ottenhoff, Tom HM; Klein, Michèl R
Humoral responses to Plasmodium falciparum blood-stage antigens and association with incidence of clinical malaria in children living in an area of seasonal malaria transmission in Burkina Faso, West Africa. (2007)
Nebie, Issa; Diarra, Amidou; Ouedraogo, Alphonse; Soulama, Issiaka; Bougouma, Edith C; Tiono, Alfred B; Konate, Amadou T; Chilengi, Roma; Theisen, Michael; Dodoo, Daniel; Remarque, Ed; Bosomprah, Samuel; Milligan, Paul; Sirima, Sodiomon B
Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis. (2007)
Stokes, Margaret GM; Titball, Richard W; Neeson, Brendan N; Galen, James E; Walker, Nicola J; Stagg, Anthony J; Jenner, Dominic C; Thwaite, Joanne E; Nataro, James P; Baillie, Leslie WJ; Atkins, Helen S
2006
Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. (2006)
Cuccui, J; Easton, A; Chu, KK; Bancroft, GJ; Oyston, PCF; Titball, RW; Wren, BW
The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection. (2006)
Holland, Martin J; Faal, Nkoyo; Sarr, Isatou; Joof, Hassan; Laye, Mass; Cameron, Ewen; Pemberton-Pigott, Frederick; Dockrell, Hazel M; Bailey, Robin L; Mabey, David CW
The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytes. (2006)
Jung, Saet-Byel; Yang, Chul-Su; Lee, Ji-Sook; Shin, A-Rum; Jung, Sung-Soo; Son, Ji Woong; Harding, Clifford V; Kim, Hwa-Jung; Park, Jeong-Kyu; Paik, Tae-Hyun; Song, Chang-Hwa; Jo, Eun-Kyeong
Immunoglobulin G antibodies to merozoite surface antigens are associated with recovery from chloroquine-resistant Plasmodium falciparum in Gambian children. (2006)
Pinder, Margaret; Sutherland, Colin J; Sisay-Joof, Fatoumatta; Ismaili, Jamila; McCall, Matthew BB; Ord, Rosalyn; Hallett, Rachel; Holder, Anthony A; Milligan, Paul
Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen. (2006)
Polley, Rosalind; Stager, Simona; Prickett, Sara; Maroof, Asher; Zubairi, Soombul; Smith, Deborah F; Kaye, Paul M
Critical role of type 1 cytokines in controlling initial infection with Burkholderia mallei. (2006)
Rowland, Caroline A; Lertmemongkolchai, Ganjana; Bancroft, Alison; Haque, Ashraful; Lever, M Stephen; Griffin, Kate F; Jackson, Matthew C; Nelson, Michelle; O'Garra, Anne; Grencis, Richard; Bancroft, Gregory J; Lukaszewski, Roman A
The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection. (2006)
Tanabe, Mikio; Atkins, Helen S; Harland, David N; Elvin, Stephen J; Stagg, Anthony J; Mirza, Osman; Titball, Richard W; Byrne, Bernadette; Brown, Katherine A
The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens. (2006)
Thomas, Rebecca M; Titball, Richard W; Oyston, Petra CF; Griffin, Kate; Waters, Emma; Hitchen, Paul G; Michell, Stephen L; Grice, I Darren; Wilson, Jennifer C; Prior, Joann L
Target antigen, age, and duration of antigen exposure independently regulate immunoglobulin G subclass switching in malaria. (2006)
Tongren, J Eric; Drakeley, Christopher J; McDonald, Suzanna LR; Reyburn, Hugh G; Manjurano, Alphaxard; Nkya, Watoky MM; Lemnge, Martha M; Gowda, Channe D; Todd, Jim E; Corran, Patrick H; Riley, Eleanor M
2005
Effects of prednisolone treatment on cytokine expression in patients with leprosy type 1 reactions. (2005)
Andersson, Anna K; Chaduvula, MeherVani; Atkinson, Sara E; Khanolkar-Young, Saroj; Jain, Suman; Suneetha, Lavanya; Suneetha, Sujai; Lockwood, Diana NJ
Toxoplasma gondii-specific immunoglobulin M limits parasite dissemination by preventing host cell invasion. (2005)
Couper, Kevin N; Roberts, Craig W; Brombacher, Frank; Alexander, James; Johnson, Lawrence L
Rapid acquisition of isolate-specific antibodies to chondroitin sulfate A-adherent plasmodium falciparum isolates in Ghanaian primigravidae. (2005)
Cox, Sharon E; Staalsoe, Trine; Arthur, Paul; Bulmer, Judith N; Hviid, Lars; Yeboah-Antwi, Kojo; Kirkwood, Betty R; Riley, Eleanor M
Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, translocation, translocation. (2005)
Garmendia, Junkal; Frankel, Gad; Crepin, Valérie F
Chronic Leishmania donovani infection promotes bystander CD8+-T-cell expansion and heterologous immunity. (2005)
Polley, Rosalind; Sanos, Stephanie L; Prickett, Sara; Haque, Ashraful; Kaye, Paul M
Invariant NKT cells are essential for the regulation of hepatic CXCL10 gene expression during Leishmania donovani infection. (2005)
Svensson, Mattias; Zubairi, Soombul; Maroof, Asher; Kazi, Fatima; Taniguchi, Masaru; Kaye, Paul M
Extensive antigenic polymorphism within the repeat sequence of the Plasmodium falciparum merozoite surface protein 1 block 2 is incorporated in a minimal polyvalent immunogen. (2005)
Tetteh, Kevin KA; Cavanagh, David R; Corran, Patrick; Musonda, Rosemary; McBride, Jana S; Conway, David J
Epitope-specific regulation of immunoglobulin class switching in mice immunized with malarial merozoite surface proteins. (2005)
Tongren, Jon Eric; Corran, Patrick H; Jarra, William; Langhorne, Jean; Riley, Eleanor M
Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment. (2005)
Woodall, CA; Jones, MA; Barrow, PA; Hinds, J; Marsden, GL; Kelly, DJ; Dorrell, N; Wren, BW; Maskell, DJ
Intestinal innate immunity to Campylobacter jejuni results in induction of bactericidal human beta-defensins 2 and 3. (2005)
Zilbauer, Matthias; Dorrell, Nick; Boughan, Parjeet K; Harris, Andrew; Wren, Brendan W; Klein, Nigel J; Bajaj-Elliott, Mona
2004
Chemokine gene expression in toll-like receptor-competent and -deficient mice infected with Leishmania major. (2004)
Antoniazi, Simone; Price, Helen P; Kropf, Pascale; Freudenberg, Marina A; Galanos, Chris; Smith, Deborah F; Müller, Ingrid
Cytokine and fibrogenic gene expression in the conjunctivas of subjects from a Gambian community where trachoma is endemic. (2004)
Burton, Matthew J; Bailey, Robin L; Jeffries, David; Mabey, David CW; Holland, Martin J
Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria. (2004)
Cavanagh, David R; Dodoo, Daniel; Hviid, Lars; Kurtzhals, Jørgen AL; Theander, Thor G; Akanmori, Bartholomew D; Polley, Spencer; Conway, David J; Koram, Kojo; McBride, Jana S
The fine specificity, but not the invasion inhibitory activity, of 19-kilodalton merozoite surface protein 1-specific antibodies is associated with resistance to malarial parasitemia in a cross-sectional survey in The Gambia. (2004)
Corran, Patrick H; O'Donnell, Rebecca A; Todd, Jim; Uthaipibull, Chairat; Holder, Anthony A; Crabb, Brendan S; Riley, Eleanor M
Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes. (2004)
Dahan, Sivan; Knutton, Stuart; Shaw, Robert K; Crepin, Valerie F; Dougan, Gordon; Frankel, Gad
ATP-binding cassette transporters are targets for the development of antibacterial vaccines and therapies. (2004)
Garmory, Helen S; Titball, Richard W
Protection afforded by heat shock protein 60 from Francisella tularensis is due to copurified lipopolysaccharide. (2004)
Hartley, MG; Green, M; Choules, G; Rogers, D; Rees, DGC; Newstead, S; Sjostedt, A; Titball, RW
Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. (2004)
Jones, Michael A; Marston, Kerrie L; Woodall, Claire A; Maskell, Duncan J; Linton, Dennis; Karlyshev, Andrey V; Dorrell, Nick; Wren, Brendan W; Barrow, Paul A
Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major. (2004)
Kropf, Pascale; Freudenberg, Marina A; Modolell, Manuel; Price, Helen P; Herath, Shanti; Antoniazi, Simone; Galanos, Chris; Smith, Deborah F; Müller, Ingrid
Age-specific immunoglobulin g (IgG) and IgA to pneumococcal protein antigens in a population in coastal kenya. (2004)
Laine, Catherine; Mwangi, Tabitha; Thompson, Claudette M; Obiero, Jacktone; Lipsitch, Marc; Scott, J Anthony G
Distinct trafficking and localization of STEVOR proteins in three stages of the Plasmodium falciparum life cycle. (2004)
McRobert, Louisa; Preiser, Peter; Sharp, Sarah; Jarra, William; Kaviratne, Mallika; Taylor, Martin C; Renia, Laurent; Sutherland, Colin J
Fine specificity of serum antibodies to Plasmodium falciparum merozoite surface protein, PfMSP-1(19), predicts protection from malaria infection and high-density parasitemia. (2004)
Okech, Brenda A; Corran, Patrick H; Todd, James; Joynson-Hicks, Amy; Uthaipibull, Chairat; Egwang, Thomas G; Holder, Anthony A; Riley, Eleanor M
Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria. (2004)
Staalsoe, Trine; Shulman, Caroline E; Dorman, Edgar K; Kawuondo, Ken; Marsh, Kevin; Hviid, Lars
Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design. (2004)
Vekemans, Johan; Ota, Martin OC; Sillah, Jackson; Fielding, Katherine; Alderson, Mark R; Skeiky, Yasir AW; Dalemans, Wilfried; McAdam, Keith PWJ; Lienhardt, Christian; Marchant, Arnaud
Mycobacterial purified protein derivatives stimulate innate immunity: Malawians show enhanced tumor necrosis factor alpha, interleukin-1beta (IL-1beta), and IL-10 responses compared to those of adolescents in the United Kingdom. (2004)
Weir, Rosemary E; Black, Gillian F; Dockrell, Hazel M; Floyd, Sian; Fine, Paul EM; Chaguluka, Steven D; Stenson, Sally; King, Elizabeth; Nazareth, Bernadette; Warndorff, David K; Ngwira, Bagrey; Crampin, Amelia C; Mwaungulu, Lorren; Sichali, Lifted; Jarman, Elizabeth; Donovan, Linda; Blackwell, Jenefer M
2003
Erythrocyte invasion phenotypes of Plasmodium falciparum in The Gambia. (2003)
Baum, Jake; Pinder, Margaret; Conway, David J
Genetic diversity and antigenic polymorphism in Plasmodium falciparum: extensive serological cross-reactivity between allelic variants of merozoite surface protein 2. (2003)
Franks, Simon; Baton, Luke; Tetteh, Kevin; Tongren, Eric; Dewin, David; Akanmori, Bartholomew D; Koram, Kojo A; Ranford-Cartwright, Lisa; Riley, Eleanor M
Salmonella enterica serovar typhimurium expressing a chromosomally integrated copy of the Bacillus anthracis protective antigen gene protects mice against an anthrax spore challenge. (2003)
Garmory, Helen S; Titball, Richard W; Griffin, Kate F; Hahn, Ulrike; Böhm, Reinhard; Beyer, Wolfgang
Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria. (2003)
Jensen, Anja TR; Zornig, Hanne D; Buhmann, Caecilie; Salanti, Ali; Koram, Kwadwo A; Riley, Eleanor M; Theander, Thor G; Hviid, Lars; Staalsoe, Trine
Signaling through the T1/ST2 molecule is not necessary for Th2 differentiation but is important for the regulation of type 1 responses in nonhealing Leishmania major infection. (2003)
Kropf, P; Herath, S; Klemenz, R; Müller, I
Pathology of Plasmodium chabaudi chabaudi infection and mortality in interleukin-10-deficient mice are ameliorated by anti-tumor necrosis factor alpha and exacerbated by anti-transforming growth factor beta antibodies. (2003)
Li, Ching; Sanni, Latifu A; Omer, Fakhreldin; Riley, Eleanor; Langhorne, Jean
Increased mortality and dysregulated cytokine production in tumor necrosis factor receptor 1-deficient mice following systemic Klebsiella pneumoniae infection. (2003)
Moore, Thomas A; Perry, Michelle L; Getsoian, Andrew G; Monteleon, Christine L; Cogen, Anna L; Standiford, Theodore J
Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis. (2003)
Parish, Tanya; Smith, Debbie A; Kendall, Sharon; Casali, Nicola; Bancroft, Gregory J; Stoker, Neil G
Repeat sequences in block 2 of Plasmodium falciparum merozoite surface protein 1 are targets of antibodies associated with protection from malaria. (2003)
Polley, Spencer D; Tetteh, Kevin KA; Cavanagh, David R; Pearce, Richard J; Lloyd, Jennifer M; Bojang, Kalifa A; Okenu, Daniel MN; Greenwood, Brian M; McBride, Jana S; Conway, David J
Interleukin-8 is differentially expressed by human-derived monocytic cell line U937 infected with Mycobacterium tuberculosis H37Rv and Mycobacterium marinum. (2003)
Song, Chang-Hwa; Lee, Ji-Sook; Kim, Hwa-Jung; Park, Jeong-Kyu; Paik, Tae-Hyun; Jo, Eun-Kyeong
Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity. (2003)
Stäger, Simona; Alexander, James; Carter, K Christine; Brombacher, Frank; Kaye, Paul M
2002
Protective immune responses to the 42-kilodalton (kDa) region of Plasmodium yoelii merozoite surface protein 1 are induced by the C-terminal 19-kDa region but not by the adjacent 33-kDa region. (2002)
Ahlborg, Niklas; Ling, Irene T; Howard, Wendy; Holder, Anthony A; Riley, Eleanor M
A mutant of Burkholderia pseudomallei, auxotrophic in the branched chain amino acid biosynthetic pathway, is attenuated and protective in a murine model of melioidosis. (2002)
Atkins, T; Prior, RG; Mack, K; Russell, P; Nelson, M; Oyston, PCF; Dougan, G; Titball, RW
Regulation of antigen-specific immunoglobulin G subclasses in response to conserved and polymorphic Plasmodium falciparum antigens in an in vitro model. (2002)
Garraud, Olivier; Perraut, Ronald; Diouf, Ababacar; Nambei, Wilfrid S; Tall, Adama; Spiegel, André; Longacre, Shirley; Kaslow, David C; Jouin, Hélène; Mattei, Denise; Engler, Gina M; Nutman, Thomas B; Riley, Eleanor M; Mercereau-Puijalon, Odile
Construction and phenotypic characterization of an auxotrophic mutant of Mycobacterium tuberculosis defective in L-arginine biosynthesis. (2002)
Gordhan, Bhavna G; Smith, Debbie A; Alderton, Heidi; McAdam, Ruth A; Bancroft, Gregory J; Mizrahi, Valerie
Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophages. (2002)
Junghae, Muthoni; Raynes, John G
HLA-B*35-restricted CD8(+)-T-cell epitope in Mycobacterium tuberculosis Rv2903c. (2002)
Klein, Michèl R; Hammond, Abdulrahman S; Smith, Steve M; Jaye, Assan; Lukey, Pauline T; McAdam, Keith PWJ
High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion. (2002)
Kocken, Clemens HM; Withers-Martinez, Chrislaine; Dubbeld, Martin A; van der Wel, Annemarie; Hackett, Fiona; Valderrama, Augusto; Blackman, Michael J; Thomas, Alan W
Identification of two distinct subpopulations of Leishmania major-specific T helper 2 cells. (2002)
Kropf, Pascale; Herath, Shanti; Tewari, Rita; Syed, Nelofer; Klemenz, Roman; Müller, Ingrid
LsaA, an antigen involved in cell attachment and invasion, is expressed by Lawsonia intracellularis during infection in vitro and in vivo. (2002)
McCluskey, Jackie; Hannigan, Joanne; Harris, Jennifer D; Wren, Brendan; Smith, David GE
Prevalence and boosting of antibodies to Plasmodium falciparum glycosylphosphatidylinositols and evaluation of their association with protection from mild and severe clinical malaria. (2002)
de Souza, J Brian; Todd, James; Krishegowda, Gowdahalli; Gowda, D Channe; Kwiatkowski, Dominic; Riley, Eleanor M
2001
Knockout of the rodent malaria parasite chitinase pbCHT1 reduces infectivity to mosquitoes. (2001)
Dessens, JT; Mendoza, J; Claudianos, C; Vinetz, JM; Khater, E; Hassard, S; Ranawaka, GR; Sinden, RE
Genetic regulation of acquired immune responses to antigens of Mycobacterium tuberculosis: a study of twins in West Africa. (2001)
Jepson, A; Fowler, A; Banya, W; Singh, M; Bennett, S; Whittle, H; Hill, AV
Demonstration of polysaccharide capsule in Campylobacter jejuni using electron microscopy. (2001)
Karlyshev, AV; McCrossan, MV; Wren, BW
Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes. (2001)
Karlyshev, AV; Oyston, PC; Williams, K; Clark, GC; Titball, RW; Winzeler, EA; Wren, BW
Immunohistochemical analysis of cellular infiltrate and gamma interferon, interleukin-12, and inducible nitric oxide synthase expression in leprosy type 1 (reversal) reactions before and during prednisolone treatment. (2001)
Little, D; Khanolkar-Young, S; Coulthart, A; Suneetha, S; Lockwood, DN
Helicobacter pylori pore-forming cytolysin orthologue TlyA possesses in vitro hemolytic activity and has a role in colonization of the gastric mucosa. (2001)
Martino, MC; Stabler, RA; Zhang, ZW; Farthing, MJ; Wren, BW; Dorrell, N
Production of matrix metalloproteinases in response to mycobacterial infection. (2001)
Quiding-Järbrink, M; Smith, DA; Bancroft, GJ
Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates. (2001)
Smith, DA; Parish, T; Stoker, NG; Bancroft, GJ
Tuberculosis contacts but not patients have higher gamma interferon responses to ESAT-6 than do community controls in The Gambia. (2001)
Vekemans, J; Lienhardt, C; Sillah, JS; Wheeler, JG; Lahai, GP; Doherty, MT; Corrah, T; Andersen, P; McAdam, KP; Marchant, A
Enhancement of Mycobacterium tuberculosis-induced tumor necrosis factor alpha production from primary human monocytes by an activated T-cell membrane-mediated mechanism. (2001)
Warwick-Davies, J; Watson, AJ; Griffin, GE; Krishna, S; Shattock, RJ
Chlamydia pneumoniae major outer membrane protein is a surface-exposed antigen that elicits antibodies primarily directed against conformation-dependent determinants. (2001)
Wolf, K; Fischer, E; Mead, D; Zhong, G; Peeling, R; Whitmire, B; Caldwell, HD