Items where the Publication is European journal of medicinal chemistry

Number of items: 15.
2021
  • Design and synthesis of Mannich base-type derivatives containing imidazole and benzimidazole as lead compounds for drug discovery in Chagas Disease. (2021) Beltran-Hortelano, Iván; Atherton, Richard L; Rubio-Hernández, Mercedes; Sanz-Serrano, Julen; Alcolea, Verónica; Kelly, John M; Pérez-Silanes, Silvia; Olmo, Francisco
    • 2020
  • Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy. (2020) Thompson, Andrew M; O'Connor, Patrick D; Marshall, Andrew J; Francisco, Amanda F; Kelly, John M; Riley, Jennifer; Read, Kevin D; Perez, Catherine J; Cornwall, Scott; Thompson, RC Andrew; Keenan, Martine; White, Karen L; Charman, Susan A; Zulfiqar, Bilal; Sykes, Melissa L; Avery, Vicky M; Chatelain, Eric; Denny, William A
    • 2017
  • Synthesis and antitrypanosomal activities of novel pyridylchalcones. (2017) Bhambra, AS; Ruparelia, KC; Tan, HL; Tasdemir, D; Burrell-Saward, H; Yardley, V; Beresford, KJ; Arroo, RR
    • 2015
  • Design, synthesis and antitrypanosomal activities of 2,6-disubstituted-4,5,7-trifluorobenzothiophenes. (2015) Bhambra, Avninder S; Edgar, Mark; Elsegood, Mark RJ; Li, Yuqi; Weaver, George W; Arroo, Randolph RJ; Yardley, Vanessa; Burrell-Saward, Hollie; Krystof, Vladimir
  • Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity. (2015) Di Pietro, Ornella; Vicente-García, Esther; Taylor, Martin C; Berenguer, Diana; Viayna, Elisabet; Lanzoni, Anna; Sola, Irene; Sayago, Helena; Riera, Cristina; Fisa, Roser; Clos, M Victòria; Pérez, Belén; Kelly, John M; Lavilla, Rodolfo; Muñoz-Torrero, Diego
  • Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative. (2015) Olmo, Francisco; Gómez-Contreras, Fernando; Navarro, Pilar; Marín, Clotilde; Yunta, María JR; Cano, Carmen; Campayo, Lucrecia; Martín-Oliva, David; Rosales, María José; Sánchez-Moreno, Manuel
    • 2014
  • Triazolopyrimidine compounds containing first-row transition metals and their activity against the neglected infectious Chagas disease and leishmaniasis. (2014) Caballero, Ana B; Rodríguez-Diéguez, Antonio; Quirós, Miguel; Salas, Juan M; Huertas, Óscar; Ramírez-Macías, Inmaculada; Olmo, Francisco; Marín, Clotilde; Chaves-Lemaur, Guillermo; Gutierrez-Sánchez, Ramón; Sánchez-Moreno, Manuel
  • Prospects of an alternative treatment against Trypanosoma cruzi based on abietic acid derivatives show promising results in Balb/c mouse model. (2014) Olmo, F; Guardia, JJ; Marin, C; Messouri, I; Rosales, MJ; Urbanová, K; Chayboun, I; Chahboun, R; Alvarez-Manzaneda, EJ; Sánchez-Moreno, M
    • 2013
  • In vitro activity of scorpiand-like azamacrocycle derivatives in promastigotes and intracellular amastigotes of Leishmania infantum and Leishmania braziliensis. (2013) Marín, Clotilde; Clares, M Paz; Ramírez-Macías, Inmaculada; Blasco, Salvador; Olmo, Francisco; Soriano, Conxa; Verdejo, Begoña; Rosales, María José; Gomez-Herrera, David; García-España, Enrique; Sánchez-Moreno, Manuel
  • Scorpiand-like azamacrocycles prevent the chronic establishment of Trypanosoma cruzi in a murine model. (2013) Olmo, Francisco; Marín, Clotilde; Clares, M Paz; Blasco, Salvador; Albelda, M Teresa; Soriano, Conxa; Gutiérrez-Sánchez, Ramón; Arrebola-Vargas, Francisco; García-España, Enrique; Sánchez-Moreno, Manuel
    • 2012
  • 2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies. (2012) Singh, Kamaljit; Kaur, Hardeep; Chibale, Kelly; Balzarini, Jan; Little, Susan; Bharatam, Prasad V
    • 2010
  • Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines. (2010) Zoidis, Grigoris; Kolocouris, Nicolas; Kelly, John M; Prathalingam, S Radhika; Naesens, Lieve; De Clercq, Erik
    • 2009
  • A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity. (2009) Guglielmo, Stefano; Bertinaria, Massimo; Rolando, Barbara; Crosetti, Marco; Fruttero, Roberta; Yardley, Vanessa; Croft, Simon L; Gasco, Alberto
    • 2007
  • Synthesis and structure-activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents. (2007) Vicente, Esther; Lima, Lidia M; Bongard, Emily; Charnaud, Sarah; Villar, Raquel; Solano, Beatriz; Burguete, Asunción; Perez-Silanes, Silvia; Aldana, Ignacio; Vivas, Livia; Monge, Antonio
    • 2003
  • Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. (2003) Ren, Hongyu; Grady, Shannon; Banghart, Matthew; Moulthrop, Jason S; Kendrick, Howard; Yardley, Vanessa; Croft, Simon L; Moyna, Guillermo