Items where the Publication is ChemMedChem
Number of items: 10.
2019
  • Synthesis and Evaluation of Nifurtimox-Adamantane Adducts with Trypanocidal Activity. (2019) Foscolos, Angeliki-Sofia; Papanastasiou, Ioannis; Tsotinis, Andrew; Taylor, Martin C; Kelly, John M
  • Substituted Aminoacetamides as Novel Leads for Malaria Treatment. (2019) Norcross, Neil R; Wilson, Caroline; Baragaña, Beatriz; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Fletcher, Daniel; Sinden, Robert; Delves, Michael; Ruecker, Andrea; Duffy, Sandra; Meister, Stephan; Antonova-Koch, Yevgeniya; Crespo, Benigno; de Cózar, Cristina; Sanz, Laura M; Gamo, Francisco Javier; Avery, Vicky M; Frearson, Julie A; Gray, David W; Fairlamb, Alan H; Winzeler, Elizabeth A; Waterson, David; Campbell, Simon F; Willis, Paul A; Read, Kevin D; Gilbert, Ian H
    • 2013
  • Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography. (2013) Baiocco, Paola; Poce, Giovanna; Alfonso, Salvatore; Cocozza, Martina; Porretta, Giulio Cesare; Colotti, Gianni; Biava, Mariangela; Moraca, Francesca; Botta, Maurizio; Yardley, Vanessa; Fiorillo, Annarita; Lantella, Antonella; Malatesta, Francesco; Ilari, Andrea
    • 2012
  • Synthesis and evaluation of 1-amino-6-halo-β-carbolines as antimalarial and antiprion agents. (2012) Thompson, Mark J; Louth, Jennifer C; Little, Susan M; Jackson, Matthew P; Boursereau, Yohan; Chen, Beining; Coldham, Iain
    • 2011
  • Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action. (2011) Chadwick, James; Amewu, Richard K; Marti, Francesc; Garah, Fatima Bousejra-El; Sharma, Raman; Berry, Neil G; Stocks, Paul A; Burrell-Saward, Hollie; Wittlin, Sergio; Rottmann, Matthias; Brun, Reto; Taramelli, Donatella; Parapini, Silvia; Ward, Stephen A; O'Neill, Paul M
    • 2010
  • NMR-guided molecular docking of a protein-peptide complex based on ant colony optimization. (2010) Korb, Oliver; Möller, Heiko M; Exner, Thomas E
    • 2009
  • Design and synthesis of Trypanosoma brucei active 1-alkyloxy and 1-benzyloxyadamantano 2-guanylhydrazones. (2009) Papanastasiou, Ioannis; Tsotinis, Andrew; Zoidis, Grigoris; Kolocouris, Nicolas; Prathalingam, S Radhika; Kelly, John M
    • 2008
  • N-myristoyltransferase: a prospective drug target for protozoan parasites. (2008) Bowyer, Paul W; Tate, Edward W; Leatherbarrow, Robin J; Holder, Anthony A; Smith, Deborah F; Brown, Katherine A
  • Reversed chloroquines based on the 3,4-dihydropyrimidin-2(1H)-one scaffold: synthesis and evaluation for antimalarial, beta-haematin inhibition, and cytotoxic activity. (2008) October, Natasha; Watermeyer, Nicholas D; Yardley, Vanessa; Egan, Timothy J; Ncokazi, Kanyile; Chibale, Kelly
    • 2007
  • Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities. (2007) Haynes, Richard K; Wong, Ho-Ning; Lee, Kin-Wo; Lung, Chung-Man; Shek, Lai Yung; Williams, Ian D; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Wong, Vincent KW; Ko, Ben CB