Items where the Publication is Bioorganic & medicinal chemistry
Number of items: 22.
2016
Antiprotozoal glutathione derivatives with flagellar membrane binding activity against T. brucei rhodesiense. (2016)
Daunes, S; Yardley, V; Croft, SL; D'Silva, C
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents. (2016)
Sola, Irene; Artigas, Albert; Taylor, Martin C; Pérez-Areales, F Javier; Viayna, Elisabet; Clos, M Victòria; Pérez, Belén; Wright, Colin W; Kelly, John M; Muñoz-Torrero, Diego
2015
Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity. (2015)
Sola, Irene; Castellà, Sílvia; Viayna, Elisabet; Galdeano, Carles; Taylor, Martin C; Gbedema, Stephen Y; Pérez, Belén; Clos, M Victòria; Jones, Deuan C; Fairlamb, Alan H; Wright, Colin W; Kelly, John M; Muñoz-Torrero, Diego
2013
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers. (2013)
Amewu, Richard K; Chadwick, James; Hussain, Afthab; Panda, Somnath; Rinki, Rinki; Janneh, Omar; Ward, Stephen A; Miguel, Candel; Burrell-Saward, Hollie; Vivas, Livia; O'Neill, Paul M
2012
Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities. (2012)
Torres, Eva; Duque, María D; López-Querol, Marta; Taylor, Martin C; Naesens, Lieve; Ma, Chunlong; Pinto, Lawrence H; Sureda, Francesc X; Kelly, John M; Vázquez, Santiago
2011
Huprines as a new family of dual acting trypanocidal-antiplasmodial agents. (2011)
Defaux, Julien; Sala, Marta; Formosa, Xavier; Galdeano, Carles; Taylor, Martin C; Alobaid, Waleed AA; Kelly, John M; Wright, Colin W; Camps, Pelayo; Muñoz-Torrero, Diego
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2010
New oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activities. (2010)
Duque, María D; Camps, Pelayo; Torres, Eva; Valverde, Elena; Sureda, Francesc X; López-Querol, Marta; Camins, Antoni; Prathalingam, S Radhika; Kelly, John M; Vázquez, Santiago
Water-soluble polymer-drug conjugates for combination chemotherapy against visceral leishmaniasis. (2010)
Nicoletti, Salvatore; Seifert, Karin; Gilbert, Ian H
2009
Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines. (2009)
Duque, María D; Camps, Pelayo; Profire, Lenuta; Montaner, Silvia; Vázquez, Santiago; Sureda, Francesc X; Mallol, Jordi; López-Querol, Marta; Naesens, Lieve; De Clercq, Erik; Prathalingam, S Radhika; Kelly, John M
2008
Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs. (2008)
Camps, Pelayo; Duque, María D; Vázquez, Santiago; Naesens, Lieve; De Clercq, Erik; Sureda, Francesc X; López-Querol, Marta; Camins, Antoni; Pallàs, Mercè; Prathalingam, S Radhika; Kelly, John M; Romero, Vanessa; Ivorra, Dolores; Cortés, Diego
2007
Metallocene-based antimalarials: an exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity in chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. (2007)
Blackie, Margaret AL; Beagley, Paul; Croft, Simon L; Kendrick, Howard; Moss, John R; Chibale, Kelly
Anti-malarial activity of N6-modified purine analogues. (2007)
Too, Kathleen; Brown, Daniel M; Bongard, Emily; Yardley, Vanessa; Vivas, Livia; Loakes, David
2005
Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics. (2005)
Lorente, Silvia Orenes; Jimenez, Carmen Jimenez; Gros, Ludovic; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; A Urbina, Julio; Ruiz-Perez, Luis M; Pacanowska, Dolores Gonzalez; Gilbert, Ian H
Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. (2005)
Orenes Lorente, Silvia; Gómez, Rosario; Jiménez, Carmen; Cammerer, Simon; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; Ruiz Perez, Luis M; Urbina, Julio; Gonzalez Pacanowska, Dolores; Gilbert, Ian H
2004
In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. (2004)
Carrico, Dora; Ohkanda, Junko; Kendrick, Howard; Yokoyama, Kohei; Blaskovich, Michelle A; Bucher, Cynthia J; Buckner, Frederick S; Van Voorhis, Wesley C; Chakrabarti, Debopam; Croft, Simon L; Gelb, Michael H; Sebti, Saïd M; Hamilton, Andrew D
Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1,2,4-oxadiazoles. (2004)
Cottrell, Denise M; Capers, Jeffrey; Salem, Manar M; DeLuca-Fradley, Kate; Croft, Simon L; Werbovetz, Karl A
Corrigendum to “Structure–activity relationships of antileishmanial and antimalarial chalcones” (Bioorg. Chem. 2003, 11, 2729–2738]. (2004)
Liu, Mei; Wilairat, Prapon; Croft, Simon L; Tan, Agnes Lay-Choo; Go, Mei-Lin
Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives. (2004)
Mäntylä, Antti; Rautio, Jarkko; Nevalainen, Tapio; Vepsälainen, Jouko; Juvonen, Risto; Kendrick, Howard; Garnier, Tracy; Croft, Simon L; Järvinen, Tomi
2003
Structure-activity relationships of antileishmanial and antimalarial chalcones. (2003)
Liu, Mei; Wilairat, Prapon; Croft, Simon L; Tan, Agnes Lay-Choo; Go, Mei-Lin
2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase. (2003)
Pez, Didier; Leal, Isabel; Zuccotto, Fabio; Boussard, Cyrille; Brun, Reto; Croft, Simon L; Yardley, Vanessa; Ruiz Perez, Luis M; Gonzalez Pacanowska, Dolores; Gilbert, Ian H