Items where Faculty or Department is "Dept of Pathogen Molecular Biology (-2019)"

LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Pathogen Molecular Biology (-2019) (1192) Month Authors/Creators Item Type Full Text

Article

Enteric fever in Cambodian children is dominated by multidrug-resistant H58 Salmonella enterica serovar Typhi with intermediate susceptibility to ciprofloxacin. (2012) Emary, Kate; Moore, Catrin E; Chanpheaktra, Ngoun; An, Khun Peng; Chheng, Kheng; Sona, Soeng; Duy, Pham Thanh; Nga, Tran Vu Thieu; Wuthiekanun, Vanaporn; Amornchai, Premjit; Kumar, Varun; Wijedoru, Lalith; Stoesser, Nicole E; Carter, Michael J; Baker, Stephen; Day, Nicholas PJ; Parry, Christopher M

Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection. (2012) Sánchez-Moreno, Manuel; Gómez-Contreras, Fernando; Navarro, Pilar; Marín, Clotilde; Olmo, Francisco; Yunta, María JR; Sanz, Ana María; Rosales, María José; Cano, Carmen; Campayo, Lucrecia

EspZ of enteropathogenic and enterohemorrhagic Escherichia coli regulates type III secretion system protein translocation. (2012) Berger, Cedric N; Crepin, Valerie F; Baruch, Kobi; Mousnier, Aurelie; Rosenshine, Ilan; Frankel, Gad

SpolPred: rapid and accurate prediction of Mycobacterium tuberculosis spoligotypes from short genomic sequences. (2012) Coll, Francesc; Mallard, Kim; Preston, Mark D; Bentley, Stephen; Parkhill, Julian; McNerney, Ruth; Martin, Nigel; Clark, Taane G

In vitro and in vivo studies of the trypanocidal activity of four terpenoid derivatives against Trypanosoma cruzi. (2012) Ramírez-Macías, Inmaculada; Marín, Clotilde; Chahboun, Rachid; Messouri, Ibtissam; Olmo, Francisco; Rosales, María José; Gutierrez-Sánchez, Ramón; Alvarez-Manzaneda, Enrique; Sánchez-Moreno, Manuel

In vitro and in vivo interrogation of bio-sprayed cells. (2012) Andreu, Nuria; Thomas, Dominique; Saraiva, Luisa; Ward, Natalie; Gustafsson, Kenth; Jayasinghe, Suwan N; Robertson, Brian D

In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: their action on acute and chronic phases of Chagas disease. (2012) Sánchez-Moreno, Manuel; Marín, Clotilde; Navarro, Pilar; Lamarque, Laurent; García-España, Enrique; Miranda, Carlos; Huertas, Oscar; Olmo, Francisco; Gómez-Contreras, Fernando; Pitarch, Javier; Arrebola, Francisco

The enteropathogenic E. coli effector EspH promotes actin pedestal formation and elongation via WASP-interacting protein (WIP). (2012) Wong, Alexander RC; Raymond, Benoit; Collins, James W; Crepin, Valerie F; Frankel, Gad

In vitro anti-leishmania evaluation of nickel complexes with a triazolopyrimidine derivative against Leishmania infantum and Leishmania braziliensis. (2012) Ramírez-Macías, Inmaculada; Maldonado, Carmen R; Marín, Clotilde; Olmo, Francisco; Gutiérrez-Sánchez, Ramón; Rosales, María J; Quirós, Miguel; Salas, Juan M; Sánchez-Moreno, Manuel

In vitro evaluation of new terpenoid derivatives against Leishmania infantum and Leishmania braziliensis. (2012) Ramírez-Macías, Inmaculada; Marín, Clotilde; Chahboun, Rachid; Olmo, Francisco; Messouri, Ibtisam; Huertas, Oscar; Rosales, María Jose; Gutierrez-Sánchez, Ramón; Alvarez-Manzaneda, Enrique; Sánchez-Moreno, Manuel

The interplay between the Escherichia coli Rho guanine nucleotide exchange factor effectors and the mammalian RhoGEF inhibitor EspH. (2012) Wong, Alexander RC; Clements, Abigail; Raymond, Benoit; Crepin, Valerie F; Frankel, Gad

Rapid measurement of antituberculosis drug activity in vitro and in macrophages using bioluminescence. (2012) Andreu, Nuria; Fletcher, Taryn; Krishnan, Nitya; Wiles, Siouxsie; Robertson, Brian D

Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes. (2012) Baker, Nicola; Glover, Lucy; Munday, Jane C; Aguinaga Andrés, David; Barrett, Michael P; de Koning, Harry P; Horn, David

Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis. (2012) Boyce, Mark; Celma, Cristina CP; Roy, Polly

The continually evolving Clostridium difficile species. (2012) Cairns, Michelle D; Stabler, Richard A; Shetty, Nandini; Wren, Brendan W

Selection of Plasmodium falciparum parasites for cytoadhesion to human brain endothelial cells. (2012) Claessens, Antoine; Rowe, J Alexandra

Characterisation of the Burkholderia pseudomallei K96243 CPS I coding region. (2012) Cuccui, J; Milne, TS; Harmer, N; George, AJ; Harding, SV; Dean, RE; Scott, AE; Sarkar-Tyson, M; Wren, BW; Titball, RW; Prior, JL

Unusual stability of messenger RNA in snake venom reveals gene expression dynamics of venom replenishment. (2012) Currier, Rachel B; Calvete, Juan J; Sanz, Libia; Harrison, Robert A; Rowley, Paul D; Wagstaff, Simon C

Characterisation of Clostridium difficile biofilm formation, a role for Spo0A. (2012) Dawson, Lisa F; Valiente, Esmeralda; Faulds-Pain, Alexandra; Donahue, Elizabeth H; Wren, Brendan W

The microbiological and clinical characteristics of invasive salmonella in gallbladders from cholecystectomy patients in kathmandu, Nepal. (2012) Dongol, Sabina; Thompson, Corinne N; Clare, Simon; Nga, Tran Vu Thieu; Duy, Pham Thanh; Karkey, Abhilasha; Arjyal, Amit; Koirala, Samir; Khatri, Nely Shrestha; Maskey, Pukar; Poudel, Sanjay; Jaiswal, Vijay Kumar; Vaidya, Sujan; Dougan, Gordon; Farrar, Jeremy J; Dolecek, Christiane; Basnyat, Buddha; Baker, Stephen

Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei. (2012) Franzén, Oscar; Talavera-López, Carlos; Ochaya, Stephen; Butler, Claire E; Messenger, Louisa A; Lewis, Michael D; Llewellyn, Martin S; Marinkelle, Cornelis J; Tyler, Kevin M; Miles, Michael A; Andersson, Björn

Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. (2012) Fritz, Heather M; Bowyer, Paul W; Bogyo, Matthew; Conrad, Patricia A; Boothroyd, John C

Trypanosomal histone γH2A and the DNA damage response. (2012) Glover, Lucy; Horn, David

Human cytomegalovirus infant infection adversely affects growth and development in maternally HIV-exposed and unexposed infants in Zambia. (2012) Gompels, UA; Larke, N; Sanz-Ramos, M; Bates, M; Musonda, K; Manno, D; Siame, J; Monze, M; Filteau, S; CIGNIS Study Group

Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids. (2012) Griffin, Carol E; Hoke, Jonathan M; Samarakoon, Upeka; Duan, Junhui; Mu, Jianbing; Ferdig, Michael T; Warhurst, David C; Cooper, Roland A

Elimination of Rhodnius prolixus in Central America. (2012) Hashimoto, Ken; Schofield, Christopher J

Emergence and global spread of epidemic healthcare-associated Clostridium difficile. (2012) He, Miao; Miyajima, Fabio; Roberts, Paul; Ellison, Louise; Pickard, Derek J; Martin, Melissa J; Connor, Thomas R; Harris, Simon R; Fairley, Derek; Bamford, Kathleen B; D'Arc, Stephanie; Brazier, Jon; Brown, Derek; Coia, John E; Douce, Gill; Gerding, Dale; Kim, Hee Jung; Koh, Tse Hsien; Kato, Haru; Senoh, Mitsutoshi; Louie, Tom; Michell, Stephen; Butt, Emma; Peacock, Sharon J; Brown, Nick M; Riley, Tom; Songer, Glen; Wilcox, Mark; Pirmohamed, Munir; Kuijper, Ed; Hawkey, Peter; Wren, Brendan W; Dougan, Gordon; Parkhill, Julian; Lawley, Trevor D

Microscopy compared to culture for the diagnosis of tuberculosis in induced sputum samples: a systematic review. (2012) Hepple, P; Ford, N; McNerney, R

Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe. (2012) Holt, Kathryn E; Baker, Stephen; Weill, François-Xavier; Holmes, Edward C; Kitchen, Andrew; Yu, Jun; Sangal, Vartul; Brown, Derek J; Coia, John E; Kim, Dong Wook; Choi, Seon Young; Kim, Su Hee; da Silveira, Wanderley D; Pickard, Derek J; Farrar, Jeremy J; Parkhill, Julian; Dougan, Gordon; Thomson, Nicholas R

Long-range transcriptional control of an operon necessary for virulence-critical ESX-1 secretion in Mycobacterium tuberculosis. (2012) Hunt, Debbie M; Sweeney, Nathan P; Mori, Luisa; Whalan, Rachael H; Comas, Iñaki; Norman, Laura; Cortes, Teresa; Arnvig, Kristine B; Davis, Elaine O; Stapleton, Melanie R; Green, Jeffrey; Buxton, Roger S

Candidate targets for Multilocus Sequence Typing of Trypanosoma cruzi: validation using parasite stocks from the Chaco Region and a set of reference strains. (2012) Lauthier, Juan J; Tomasini, Nicolás; Barnabé, Christian; Rumi, María M Monje; D'Amato, Anahí M Alberti; Ragone, Paula G; Yeo, Matthew; Lewis, Michael D; Llewellyn, Martin S; Basombrío, Miguel A; Miles, Michael A; Tibayrenc, Michel; Diosque, Patricio

Fool's gold: Why imperfect reference tests are undermining the evaluation of novel diagnostics: a reevaluation of 5 diagnostic tests for leptospirosis. (2012) Limmathurotsakul, Direk; Turner, Elizabeth L; Wuthiekanun, Vanaporn; Thaipadungpanit, Janjira; Suputtamongkol, Yupin; Chierakul, Wirongrong; Smythe, Lee D; Day, Nicholas PJ; Cooper, Ben; Peacock, Sharon J

Quantification of markers of antimalarial drug resistance from an area of high malaria transmission: Comparing frequency with prevalence. (2012) Malisa, Allen

Multiple mitochondrial introgression events and heteroplasmy in trypanosoma cruzi revealed by maxicircle MLST and next generation sequencing. (2012) Messenger, Louisa A; Llewellyn, Martin S; Bhattacharyya, Tapan; Franzén, Oscar; Lewis, Michael D; Ramírez, Juan David; Carrasco, Hernan J; Andersson, Björn; Miles, Michael A

Whole-genome reconstruction and mutational signatures in gastric cancer. (2012) Nagarajan, Niranjan; Bertrand, Denis; Hillmer, Axel M; Zang, Zhi Jiang; Yao, Fei; Jacques, Pierre-Étienne; Teo, Audrey SM; Cutcutache, Ioana; Zhang, Zhenshui; Lee, Wah Heng; Sia, Yee Yen; Gao, Song; Ariyaratne, Pramila N; Ho, Andrea; Woo, Xing Yi; Veeravali, Lavanya; Ong, Choon Kiat; Deng, Niantao; Desai, Kartiki V; Khor, Chiea Chuen; Hibberd, Martin L; Shahab, Atif; Rao, Jaideepraj; Wu, Mengchu; Teh, Ming; Zhu, Feng; Chin, Sze Yung; Pang, Brendan; So, Jimmy BY; Bourque, Guillaume; Soong, Richie; Sung, Wing-Kin; Tean Teh, Bin; Rozen, Steven; Ruan, Xiaoan; Yeoh, Khay Guan; Tan, Patrick BO; Ruan, Yijun

A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients. (2012) Nguyen, Nguyet Minh; Tran, Chau Nguyen Bich; Phung, Lam Khanh; Duong, Kien Thi Hue; Huynh, Huy le Anh; Farrar, Jeremy; Nguyen, Quyen Than Ha; Tran, Hien Tinh; Nguyen, Chau Van Vinh; Merson, Laura; Hoang, Long Truong; Hibberd, Martin L; Aw, Pauline PK; Wilm, Andreas; Nagarajan, Niranjan; Nguyen, Dung Thi; Pham, Mai Phuong; Nguyen, Truong Thanh; Javanbakht, Hassan; Klumpp, Klaus; Hammond, Janet; Petric, Rosemary; Wolbers, Marcel; Nguyen, Chinh Tran; Simmons, Cameron P

Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis. (2012) Ottenhoff, Tom HM; Dass, Ranjeeta Hari; Yang, Ninghan; Zhang, Mingzi M; Wong, Hazel EE; Sahiratmadja, Edhyana; Khor, Chiea Chuen; Alisjahbana, Bachti; van Crevel, Reinout; Marzuki, Sangkot; Seielstad, Mark; van de Vosse, Esther; Hibberd, Martin L

Diabetes with hypertension as risk factors for adult dengue hemorrhagic fever in a predominantly dengue serotype 2 epidemic: a case control study. (2012) Pang, Junxiong; Salim, Agus; Lee, Vernon J; Hibberd, Martin L; Chia, Kee Seng; Leo, Yee Sin; Lye, David C

A genome wide association study of pulmonary tuberculosis susceptibility in Indonesians. (2012) Png, Eileen; Alisjahbana, Bachti; Sahiratmadja, Edhyana; Marzuki, Sangkot; Nelwan, Ron; Balabanova, Yanina; Nikolayevskyy, Vladyslav; Drobniewski, Francis; Nejentsev, Sergey; Adnan, Iskandar; van de Vosse, Esther; Hibberd, Martin L; van Crevel, Reinout; Ottenhoff, Tom HM; Seielstad, Mark

VarB: a variation browsing and analysis tool for variants derived from next-generation sequencing data. (2012) Preston, Mark D; Manske, Magnus; Horner, Neil; Assefa, Samuel; Campino, Susana; Auburn, Sarah; Zongo, Issaka; Ouedraogo, Jean-Bosco; Nosten, Francois; Anderson, Tim; Clark, Taane G

Contemporary cryptic sexuality in Trypanosoma cruzi. (2012) Ramírez, Juan David; Guhl, Felipe; Messenger, Louisa A; Lewis, Michael D; Montilla, Marleny; Cucunuba, Zulma; Miles, Michael A; Llewellyn, Martin S

Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations. (2012) Stabler, Richard A; Dawson, Lisa F; Valiente, Esmeralda; Cairns, Michelle D; Martin, Melissa J; Donahue, Elizabeth H; Riley, Thomas V; Songer, J Glenn; Kuijper, Ed J; Dingle, Kate E; Wren, Brendan W

Protective efficacy of Bluetongue virus-like and subvirus-like particles in sheep: Presence of the serotype-specific VP2, independent of its geographic lineage, is essential for protection. (2012) Stewart, M; Dovas, CI; Chatzinasiou, E; Athmaram, TN; Papanastassopoulou, M; Papadopoulos, O; Roy, P

The co-selection of fluoroquinolone resistance genes in the gut flora of Vietnamese children. (2012) Vien, Le Thi Minh; Minh, Ngo Ngoc Quang; Thuong, Tang Chi; Khuong, Huynh Duy; Nga, Tran Vu Thieu; Thompson, Corinne; Campbell, James I; de Jong, Menno; Farrar, Jeremy J; Schultsz, Constance; van Doorn, H Rogier; Baker, Stephen

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma. (2012) Vithana, Eranga N; Khor, Chiea-Chuen; Qiao, Chunyan; Nongpiur, Monisha E; George, Ronnie; Chen, Li-Jia; Do, Tan; Abu-Amero, Khaled; Huang, Chor Kai; Low, Sancy; Tajudin, Liza-Sharmini A; Perera, Shamira A; Cheng, Ching-Yu; Xu, Liang; Jia, Hongyan; Ho, Ching-Lin; Sim, Kar Seng; Wu, Ren-Yi; Tham, Clement CY; Chew, Paul TK; Su, Daniel H; Oen, Francis T; Sarangapani, Sripriya; Soumittra, Nagaswamy; Osman, Essam A; Wong, Hon-Tym; Tang, Guangxian; Fan, Sujie; Meng, Hailin; Huong, Dao TL; Wang, Hua; Feng, Bo; Baskaran, Mani; Shantha, Balekudaru; Ramprasad, Vedam L; Kumaramanickavel, Govindasamy; Iyengar, Sudha K; How, Alicia C; Lee, Kelvin Y; Sivakumaran, Theru A; Yong, Victor HK; Ting, Serena ML; Li, Yang; Wang, Ya-Xing; Tay, Wan-Ting; Sim, Xueling; Lavanya, Raghavan; Cornes, Belinda K; Zheng, Ying-Feng; Wong, Tina T; Loon, Seng-Chee; Yong, Vernon KY; Waseem, Naushin; Yaakub, Azhany; Chia, Kee-Seng; Allingham, R Rand; Hauser, Michael A; Lam, Dennis SC; Hibberd, Martin L; Bhattacharya, Shomi S; Zhang, Mingzhi; Teo, Yik Ying; Tan, Donald T; Jonas, Jost B; Tai, E-Shyong; Saw, Seang-Mei; Hon, Do Nhu; Al-Obeidan, Saleh A; Liu, Jianjun; Chau, Tran Nguyen Bich; Simmons, Cameron P; Bei, Jin-Xin; Zeng, Yi-Xin; Foster, Paul J; Vijaya, Lingam; Wong, Tien-Yin; Pang, Chi-Pui; Wang, Ningli; Aung, Tin

Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases. (2012) Walker, Naomi F; Clark, Simon O; Oni, Tolu; Andreu, Nuria; Tezera, Liku; Singh, Shivani; Saraiva, Luísa; Pedersen, Bernadette; Kelly, Dominic L; Tree, Julia A; D'Armiento, Jeanine M; Meintjes, Graeme; Mauri, Francesco A; Williams, Ann; Wilkinson, Robert J; Friedland, Jon S; Elkington, Paul T

Changing epidemiology of Clostridium difficile infection following the introduction of a national ribotyping-based surveillance scheme in England. (2012) Wilcox, MH; Shetty, N; Fawley, WN; Shemko, M; Coen, P; Birtles, A; Cairns, M; Curran, MD; Dodgson, KJ; Green, SM; Hardy, KJ; Hawkey, PM; Magee, JG; Sails, AD; Wren, MWD

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets. (2012) Wilm, Andreas; Aw, Pauline Poh Kim; Bertrand, Denis; Yeo, Grace Hui Ting; Ong, Swee Hoe; Wong, Chang Hua; Khor, Chiea Chuen; Petric, Rosemary; Hibberd, Martin Lloyd; Nagarajan, Niranjan

Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia. (2012) Wong, Michelle; Öhrmalm, Lars; Broliden, Kristina; Aust, Carl; Hibberd, Martin; Tolfvenstam, Thomas

A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging. (2012) Zelmer, Andrea; Carroll, Paul; Andreu, Nuria; Hagens, Kristine; Mahlo, Jacqueline; Redinger, Natalja; Robertson, Brian D; Wiles, Siouxsie; Ward, Theresa H; Parish, Tanya; Ripoll, Jorge; Bancroft, Gregory J; Schaible, Ulrich E

The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. (2012) Zingales, Bianca; Miles, Michael A; Campbell, David A; Tibayrenc, Michel; Macedo, Andrea M; Teixeira, Marta MG; Schijman, Alejandro G; Llewellyn, Martin S; Lages-Silva, Eliane; Machado, Carlos R; Andrade, Sonia G; Sturm, Nancy R

North American import? Charting the origins of an enigmatic Trypanosoma cruzi domestic genotype. (2012) Zumaya-Estrada, Federico A; Messenger, Louisa A; Lopez-Ordonez, Teresa; Lewis, Michael D; Flores-Lopez, Carlos A; Martínez-Ibarra, Alejandro J; Pennington, Pamela M; Cordon-Rosales, Celia; Carrasco, Hernan V; Segovia, Maikel; Miles, Michael A; Llewellyn, Martin S

Thesis

The significance of 'Blastocystis' in different hosts. (2012) Alfellani, Mohamed

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Multi-Tasking Gene Analyser Boosts Trypanosomiasis Treatment Hopes - 26 Jan 2012. (2012) UNSPECIFIED audio_file

Malaria Resistance Genes: Implications For Spread Of Artemisinin Resistance - 23 Jan 2012. (2012) UNSPECIFIED audio_file