LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Pathogen Molecular Biology (-2019) (1192) Month Authors/Creators Item Type Full Text

Article

The T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals. (2009) Bulgin, Richard; Arbeloa, Ana; Goulding, David; Dougan, Gordon; Crepin, Valerie F; Raymond, Benoit; Frankel, Gad

Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo. (2009) Crepin, Valérie F; Girard, Francis; Schüller, Stephanie; Phillips, Alan D; Mousnier, Aurelie; Frankel, Gad

Intestinal microbiota regulate xenobiotic metabolism in the liver. (2009) Björkholm, Britta; Bok, Chek Mei; Lundin, Annelie; Rafter, Joseph; Hibberd, Martin Lloyd; Pettersson, Sven

Genetics and Genomics of Infectious Diseases: advancing our understanding of host/pathogens and their interactions. (2009) Yang, Ninghan; Hibberd, Martin L

Genome-wide association studies are coming for human infectious diseases. (2009) Davila, Sonia; Hibberd, Martin L

Modelling of infection by enteropathogenic Escherichia coli strains in lineages 2 and 4 ex vivo and in vivo by using Citrobacter rodentium expressing TccP. (2009) Girard, Francis; Crepin, Valérie F; Frankel, Gad

Sexual transmission of intestinal parasites in men who have sex with men. (2009) Abdolrasouli, Alireza; McMillan, Alexander; Ackers, John P

Amantadine- and oseltamivir-resistant variants of influenza A viruses in Thailand. (2009) Bai, Gui-Rong; Chittaganpitch, Malinee; Kanai, Yuta; Li, Yong-Gang; Auwanit, Wattana; Ikuta, Kazuyoshi; Sawanpanyalert, Pathom

Predominant human herpesvirus 6 variant A infant infections in an HIV-1 endemic region of Sub-Saharan Africa. (2009) Bates, Matthew; Monze, Mwaka; Bima, Humphrey; Kapambwe, Mirriam; Clark, David; Kasolo, Francis C; Gompels, Ursula A

The pneumococcal response to oxidative stress includes a role for Rgg. (2009) Bortoni, Magda E; Terra, Vanessa S; Hinds, Jason; Andrew, Peter W; Yesilkaya, Hasan

A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. (2009) Burgner, David; Davila, Sonia; Breunis, Willemijn B; Ng, Sarah B; Li, Yi; Bonnard, Carine; Ling, Ling; Wright, Victoria J; Thalamuthu, Anbupalam; Odam, Miranda; Shimizu, Chisato; Burns, Jane C; Levin, Michael; Kuijpers, Taco W; Hibberd, Martin L; International Kawasaki Disease Genetics Consortium

CCR5 signalling, but not DARC or D6 regulatory, chemokine receptors are targeted by herpesvirus U83A chemokine which delays receptor internalisation via diversion to a caveolin-linked pathway. (2009) Catusse, Julie; Clark, David J; Gompels, Ursula A

A viral nonstructural protein regulates bluetongue virus trafficking and release. (2009) Celma, Cristina CP; Roy, Polly

Clostridium difficile--a continually evolving and problematic pathogen. (2009) Dawson, Lisa F; Valiente, Esmeralda; Wren, Brendan W

Trypanosoma vivax displays a clonal population structure. (2009) Duffy, Craig W; Morrison, Liam J; Black, Alana; Pinchbeck, Gina L; Christley, Robert M; Schoenefeld, Andreas; Tait, Andy; Turner, C Michael R; MacLeod, Annette

A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein. (2009) Emerson, Jenny E; Reynolds, Catherine B; Fagan, Robert P; Shaw, Helen A; Goulding, David; Fairweather, Neil F

Site-specific DNA double-strand breaks greatly increase stable transformation efficiency in Trypanosoma brucei. (2009) Glover, Lucy; Horn, David

Antigenic variation: extending the reach of telomeric silencing. (2009) Horn, David

Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH. (2009) Jenkins, Claire; Bacon, Joanna; Allnutt, Jon; Hatch, Kim A; Bose, Alpana; O'Sullivan, Denise M; Arnold, Catherine; Gillespie, Stephen H; McHugh, Timothy D

The O2 sensitivity of the transcription factor FNR is controlled by Ser24 modulating the kinetics of [4Fe-4S] to [2Fe-2S] conversion. (2009) Jervis, Adrian J; Crack, Jason C; White, Gaye; Artymiuk, Peter J; Cheesman, Myles R; Thomson, Andrew J; Le Brun, Nick E; Green, Jeffrey

Gallbladder carriage of Salmonella paratyphi A may be an important factor in the increasing incidence of this infection in South Asia. (2009) Khatri, Nely Shrestha; Maskey, Pukar; Poudel, Sanjay; Jaiswal, Vijay Kumar; Karkey, Abhilasha; Koirala, Samir; Shakya, Nikki; Agrawal, Krishna; Arjyal, Amit; Basnyat, Buddha; Day, Jeremy; Farrar, Jeremy; Dolecek, Christiane; Baker, Stephen

A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum. (2009) Leber, Werner; Skippen, Alison; Fivelman, Quinton L; Bowyer, Paul W; Cockcroft, Shamshad; Baker, David A

Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in Trypanosoma cruzi populations and expose contrasts between natural and experimental hybrids. (2009) Lewis, Michael D; Llewellyn, Martin S; Gaunt, Michael W; Yeo, Matthew; Carrasco, Hernán J; Miles, Michael A

Genotyping of Trypanosoma cruzi: systematic selection of assays allowing rapid and accurate discrimination of all known lineages. (2009) Lewis, Michael D; Ma, Jonathan; Yeo, Matthew; Carrasco, Hernán J; Llewellyn, Martin S; Miles, Michael A

Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. (2009) Llewellyn, Martin S; Lewis, Michael D; Acosta, Nidia; Yeo, Matthew; Carrasco, Hernan J; Segovia, Maikell; Vargas, Jorge; Torrico, Faustino; Miles, Michael A; Gaunt, Michael W

Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection. (2009) Llewellyn, Martin S; Miles, Michael A; Carrasco, Hernan J; Lewis, Michael D; Yeo, Matthew; Vargas, Jorge; Torrico, Faustino; Diosque, Patricio; Valente, Vera; Valente, Sebastiao A; Gaunt, Michael W

Patterns of gene transcript abundance in the blood of children with severe or uncomplicated dengue highlight differences in disease evolution and host response to dengue virus infection. (2009) Long, Hoang Truong; Hibberd, Martin L; Hien, Tran Tinh; Dung, Nguyen Minh; Van Ngoc, Tran; Farrar, Jeremy; Wills, Bridget; Simmons, Cameron P

Comparative phylogeography of Trypanosoma cruzi TCIIc: new hosts, association with terrestrial ecotopes, and spatial clustering. (2009) Marcili, Arlei; Lima, Luciana; Valente, Vera C; Valente, Sebastião A; Batista, Jael S; Junqueira, Angela CV; Souza, Alda I; da Rosa, João A; Campaner, Marta; Lewis, Michael D; Llewellyn, Martin S; Miles, Michael A; Teixeira, Marta MG

Bluetongue virus VP6 acts early in the replication cycle and can form the basis of chimeric virus formation. (2009) Matsuo, Eiko; Roy, Polly

Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola. (2009) Menegon, Michela; Pearce, Richard J; Inojosa, Walter O; Pisani, Vincenzo; Abel, Paulo M; Matondo, Alexandre; Bisoffi, Zeno; Majori, Giancarlo; Ord, Rosalynn; Warhurst, David C; Roper, Cally; Severini, Carlo

The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future. (2009) Miles, MA; Llewellyn, MS; Lewis, MD; Yeo, M; Baleela, R; Fitzpatrick, S; Gaunt, MW; Mauricio, IL

Genetics. Leishmania exploit sex. (2009) Miles, Michael A; Yeo, Matthew; Mauricio, Isabel L

Multigene expression of protein complexes by iterative modification of genomic Bacmid DNA. (2009) Noad, Rob J; Stewart, Meredith; Boyce, Mark; Celma, Cristina C; Willison, Keith R; Roy, Polly

Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine. (2009) O'Neill, Paul M; Shone, Alison E; Stanford, Deborah; Nixon, Gemma; Asadollahy, Eghbaleh; Park, B Kevin; Maggs, James L; Roberts, Phil; Stocks, Paul A; Biagini, Giancarlo; Bray, Patrick G; Davies, Jill; Berry, Neil; Hall, Charlotte; Rimmer, Karen; Winstanley, Peter A; Hindley, Stephen; Bambal, Ramesh B; Davis, Charles B; Bates, Martin; Gresham, Stephanie L; Brigandi, Richard A; Gomez-de-Las-Heras, Federico M; Gargallo, Domingo V; Parapini, Silvia; Vivas, Livia; Lander, Hollie; Taramelli, Donatella; Ward, Stephen A

Development of a multilocus microsatellite typing approach for discriminating strains of Leishmania (Viannia) species. (2009) Oddone, Rolando; Schweynoch, Carola; Schönian, Gabriele; de Sousa, Cintia dos Santos; Cupolillo, Elisa; Espinosa, Diego; Arevalo, Jorge; Noyes, Harry; Mauricio, Isabel; Kuhls, Katrin

Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. (2009) Rowe, J Alexandra; Claessens, Antoine; Corrigan, Ruth A; Arman, Mònica

Sequence diversity and evolutionary dynamics of the dimorphic antigen merozoite surface protein-6 and other Msp genes of Plasmodium falciparum. (2009) Roy, Scott W; Weedall, Gareth D; da Silva, Rogério L; Polley, Spencer D; Ferreira, Marcelo U

Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. (2009) Schnick, Claudia; Polley, Spencer D; Fivelman, Quinton L; Ranford-Cartwright, Lisa C; Wilkinson, Shane R; Brannigan, James A; Wilkinson, Anthony J; Baker, David A

Classification, evolution, and species groups within the Triatominae. (2009) Schofield, CJ; Galvão, Cleber

Genomic epidemiology of a dengue virus epidemic in urban Singapore. (2009) Schreiber, Mark J; Holmes, Edward C; Ong, Swee Hoe; Soh, Harold SH; Liu, Wei; Tanner, Lukas; Aw, Pauline PK; Tan, Hwee Cheng; Ng, Lee Ching; Leo, Yee Sin; Low, Jenny GH; Ong, Adrian; Ooi, Eng Eong; Vasudevan, Subhash G; Hibberd, Martin L

Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes. (2009) Smargiasso, Nicolas; Gabelica, Valérie; Damblon, Christian; Rosu, Frédéric; De Pauw, Edwin; Teulade-Fichou, Marie-Paule; Rowe, J Alexandra; Claessens, Antoine

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. (2009) Stabler, Richard A; He, Miao; Dawson, Lisa; Martin, Melissa; Valiente, Esmeralda; Corton, Craig; Lawley, Trevor D; Sebaihia, Mohammed; Quail, Michael A; Rose, Graham; Gerding, Dale N; Gibert, Maryse; Popoff, Michel R; Parkhill, Julian; Dougan, Gordon; Wren, Brendan W

Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei. (2009) Tippayawat, Patcharaporn; Saenwongsa, Wipawee; Mahawantung, Jirawan; Suwannasaen, Duangchan; Chetchotisakd, Ploenchan; Limmathurotsakul, Direk; Peacock, Sharon J; Felgner, Philip L; Atkins, Helen S; Titball, Richard W; Bancroft, Gregory J; Lertmemongkolchai, Ganjana

Genetics of susceptibility to Plasmodium falciparum: from classical malaria resistance genes towards genome-wide association studies. (2009) Verra, F; Mangano, VD; Modiano, D

Trypanocidal drugs: mechanisms, resistance and new targets. (2009) Wilkinson, SR; and Kelly, JM

Pyruvate formate lyase is required for pneumococcal fermentative metabolism and virulence. (2009) Yesilkaya, Hasan; Spissu, Francesca; Carvalho, Sandra M; Terra, Vanessa S; Homer, Karen A; Benisty, Rachel; Porat, Nurith; Neves, Ana R; Andrew, Peter W

Book Section

Comparative genomics of Clostridium difficile. (2009) Dawson, LF; Stabler, RA; Wren, BW

The Three Bears and Virulence-Associated Plasmids in the Genus Yersinia. (2009) Howard, SL; Strong, PC; Wren, BW

Potentially Pathogenic Free-living Amoebae. (2009) Warhurst, DC

Conference or Workshop Item

Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome and functional characterisation of selected genes involved in strain pathogenesis. (2009) Gundogdu, O; Elmi, A; Mills, DC; Bentley, SD; Holden, MT; Parkhill, J; Wren, WB; Dorrell, N

Malaria genomics meets drug-resistance phenotyping in the field. (2009) Hunt, P; Macinnis, B; Roper, C