LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Immunology and Infection (-2019) (972) Month Authors/Creators Item Type Full Text

Article

The breadth, but not the magnitude, of circulating memory B cell responses to P. falciparum increases with age/exposure in an area of low transmission. (2011) Nogaro, Sarah I; Hafalla, Julius C; Walther, Brigitte; Remarque, Edmond J; Tetteh, Kevin KA; Conway, David J; Riley, Eleanor M; Walther, Michael picture_as_pdf

Systemic effector and regulatory immune responses to chlamydial antigens in trachomatous trichiasis. (2011) Gall, Alevtina; Horowitz, Amir; Joof, Hassan; Natividad, Angels; Tetteh, Kevin; Riley, Eleanor; Bailey, Robin L; Mabey, David CW; Holland, Martin J

Blood transfer devices for malaria rapid diagnostic tests: evaluation of accuracy, safety and ease of use. (2011) Hopkins, Heidi; Oyibo, Wellington; Luchavez, Jennifer; Mationg, Mary Lorraine; Asiimwe, Caroline; Albertini, Audrey; González, Iveth J; Gatton, Michelle L; Bell, David

Malaria diagnostic testing and treatment practices in three different Plasmodium falciparum transmission settings in Tanzania: before and after a government policy change. (2011) Bastiaens, Guido JH; Schaftenaar, Erik; Ndaro, Arnold; Keuter, Monique; Bousema, Teun; Shekalaghe, Seif A picture_as_pdf

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children. (2011) Bejon, Philip; Cook, Jackie; Bergmann-Leitner, Elke; Olotu, Ally; Lusingu, John; Mwacharo, Jedidah; Vekemans, Johan; Njuguna, Patricia; Leach, Amanda; Lievens, Marc; Dutta, Sheetij; von Seidlein, Lorenz; Savarese, Barbara; Villafana, Tonya; Lemnge, Martha M; Cohen, Joe; Marsh, Kevin; Corran, Patrick H; Angov, Evelina; Riley, Eleanor M; Drakeley, Chris J

Human immune responses that reduce the transmission of Plasmodium falciparum in African populations. (2011) Bousema, Teun; Sutherland, Colin J; Churcher, Thomas S; Mulder, Bert; Gouagna, Louis C; Riley, Eleanor M; Targett, Geoffrey AT; Drakeley, Chris J picture_as_pdf

Low-dose exposure of C57BL/6 mice to burkholderia pseudomallei mimics chronic human melioidosis. (2011) Conejero, Laura; Patel, Natasha; de Reynal, Melanie; Oberdorf, Sara; Prior, Joanne; Felgner, Philip L; Titball, Richard W; Salguero, Francisco J; Bancroft, Gregory J

Serological markers suggest heterogeneity of effectiveness of malaria control interventions on Bioko Island, equatorial Guinea. (2011) Cook, Jackie; Kleinschmidt, Immo; Schwabe, Christopher; Nseng, Gloria; Bousema, Teun; Corran, Patrick H; Riley, Eleanor M; Drakeley, Chris J picture_as_pdf

Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child? (2011) Elliott, Alison M; Ndibazza, Juliet; Mpairwe, Harriet; Muhangi, Lawrence; Webb, Emily L; Kizito, Dennison; Mawa, Patrice; Tweyongyere, Robert; Muwanga, Moses; Entebbe Mother and Baby Study Team

A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG. (2011) Evans, J Henry; Horowitz, Amir; Mehrabi, Maryam; Wise, Emma L; Pease, James E; Riley, Eleanor M; Davis, Daniel M

Arginine depletion as a mechanism for the immune privilege of corneal allografts. (2011) Fu, Hongmei; Khan, Adnan; Coe, David; Zaher, Sarah; Chai, Jian-Guo; Kropf, Pascale; Müller, Ingrid; Larkin, Daniel FP; George, Andrew JT

Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine. (2011) Gadalla, Nahla B; Adam, Ishag; Elzaki, Salah-Eldin; Bashir, Sahar; Mukhtar, Izdihar; Oguike, Mary; Gadalla, Amal; Mansour, Fathi; Warhurst, David; El-Sayed, Badria B; Sutherland, Colin J

Systemic effector and regulatory immune responses to chlamydial antigens in Trachomatous Trichiasis. (2011) Gall, A; Horowitz, A; Joof, H; Natividad, A; Tetteh, K; Riley, E; Bailey, RL; Mabey, DCW; Holland, MJ

Malaria vaccines and the new malaria agenda. (2011) Greenwood, BM; Targett, GAT

The mysteries of immunity to malaria. (2011) Greenwood, Brian; Targett, Geoffrey

Experimental cerebral malaria develops independently of Card9 signalling. (2011) Hafalla, JC; Burgold, J; Dorhoi, A; Gross, O; Ruland, J; Kaufmann, SH; Matuschewski, K

The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine. (2011) Hassan, Moustapha; Sallam, Hatem; Hassan, Zuzana

Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis. (2011) Herbst, Susanne; Schaible, Ulrich E; Schneider, Bianca E

Activation of natural killer cells during microbial infections. (2011) Horowitz, Amir; Stegmann, Kerstin A; Riley, Eleanor M

Synthesis of Aminoquinoline-based Aminoalcohols and Oxazolidinones and Their Antiplasmodial Activity. (2011) Kobarfard, F; Yardley, V; Little, S; Daryaee, F; Chibale, K

How much remains undetected? Probability of molecular detection of human Plasmodia in the field. (2011) Koepfli, Cristian; Schoepflin, Sonja; Bretscher, Michael; Lin, Enmoore; Kiniboro, Benson; Zimmerman, Peter A; Siba, Peter; Smith, Thomas A; Mueller, Ivo; Felger, Ingrid

The relevance of non-human primate and rodent malaria models for humans. (2011) Langhorne, Jean; Buffet, Pierre; Galinski, Mary; Good, Michael; Harty, John; Leroy, Didier; Mota, Maria M; Pasini, Erica; Renia, Laurent; Riley, Eleanor; Stins, Monique; Duffy, Patrick

Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania. (2011) Manjurano, Alphaxard; Okell, Lucy; Lukindo, Tedson; Reyburn, Hugh; Olomi, Raimos; Roper, Cally; Clark, Taane G; Joseph, Sarah; Riley, Eleanor M; Drakeley, Chris

Second generation analogues of RKA182: synthetic tetraoxanes with outstanding in vitro and in vivo antimalarial activities. (2011) Marti, F; Chadwick, J; Amewu, RK; Burrell-Saward, H; Srivastava, A; Ward, SA; Sharma, R; Berry, N; O'Neill, PM; Se, DA

Second generation analogues of RKA182: synthetic tetraoxanes with outstanding in vitro and in vivo antimalarial activities. (2011) Marti, F; Chadwick, J; Amewu, RK; Burrell-Saward, H; Srivastava, A; Ward, SA; Sharma, R; Berry, N; O'Neill, PM; Se, DA

Evaluation of the time resolved fluorescence immunoassay (TRFIA) for the detection of varicella zoster virus (VZV) antibodies following vaccination of healthcare workers. (2011) McDonald, SLR; Maple, PAC; Andrews, N; Brown, KE; Ayres, KL; Scott, FT; Al Bassam, M; Gershon, AA; Steinberg, SP; Breuer, J

The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria. (2011) Mimche, Patrice N; Taramelli, Donatella; Vivas, Livia

Soil-transmitted helminthiasis in rural south-west China: prevalence, intensity and risk factor analysis. (2011) Mofid, Layla S; Bickle, Quentin; Jiang, Jin-Yong; Du, Zun-Wei; Patrick, Edward

Differentiation of human thymic regulatory T cells at the double positive stage. (2011) Nunes-Cabaço, Helena; Caramalho, Iris; Sepúlveda, Nuno; Sousa, Ana E

Integrated dataset of screening hits against multiple neglected disease pathogens. (2011) Nwaka, Solomon; Besson, Dominique; Ramirez, Bernadette; Maes, Louis; Matheeussen, An; Bickle, Quentin; Mansour, Nuha R; Yousif, Fouad; Townson, Simon; Gokool, Suzanne; Cho-Ngwa, Fidelis; Samje, Moses; Misra-Bhattacharya, Shailja; Murthy, PK; Fakorede, Foluke; Paris, Jean-Marc; Yeates, Clive; Ridley, Robert; Van Voorhis, Wesley C; Geary, Timothy

Plasmodium ovale curtisi and Plasmodium ovale wallikeri circulate simultaneously in African communities. (2011) Oguike, Mary Chiaka; Betson, Martha; Burke, Martina; Nolder, Debbie; Stothard, J Russell; Kleinschmidt, Immo; Proietti, Carla; Bousema, Teun; Ndounga, Mathieu; Tanabe, Kazuyuki; Ntege, Edward; Culleton, Richard; Sutherland, Colin J

Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensis. (2011) Okeola, Valeelat O; Adaramoye, Oluwatosin A; Nneji, Chiaka M; Falade, Catherine O; Farombi, E Olatunde; Ademowo, Olusegun G

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial. (2011) Olotu, Ally; Lusingu, John; Leach, Amanda; Lievens, Marc; Vekemans, Johan; Msham, Salum; Lang, Trudie; Gould, Jayne; Dubois, Marie-Claude; Jongert, Erik; Vansadia, Preeti; Carter, Terrell; Njuguna, Patricia; Awuondo, Ken O; Malabeja, Anangisye; Abdul, Omar; Gesase, Samwel; Mturi, Neema; Drakeley, Chris J; Savarese, Barbara; Villafana, Tonya; Lapierre, Didier; Ballou, W Ripley; Cohen, Joe; Lemnge, Martha M; Peshu, Norbert; Marsh, Kevin; Riley, Eleanor M; von Seidlein, Lorenz; Bejon, Philip

Naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs48/45 and Pfs230 in an area of seasonal transmission. (2011) Ouédraogo, André Lin; Roeffen, Will; Luty, Adrian JF; de Vlas, Sake J; Nebie, Issa; Ilboudo-Sanogo, Edith; Cuzin-Ouattara, Nadine; Teleen, Karina; Tiono, Alfred B; Sirima, Sodiomon Bienvenu; Verhave, Jan-Peter; Bousema, Teun; Sauerwein, Robert

Development of vaccines against burkholderia pseudomallei. (2011) Patel, Natasha; Conejero, Laura; De Reynal, Melanie; Easton, Anna; Bancroft, Gregory J; Titball, Richard W

The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production. (2011) Paveley, Ross A; Aynsley, Sarah A; Turner, Joseph D; Bourke, Claire D; Jenkins, Stephen J; Cook, Peter C; Martinez-Pomares, Luisa; Mountford, Adrian P

Continuing intense malaria transmission in northern Uganda. (2011) Proietti, Carla; Pettinato, Davide D; Kanoi, Bernard N; Ntege, Edward; Crisanti, Andrea; Riley, Eleanor M; Egwang, Thomas G; Drakeley, Chris; Bousema, Teun

Wild mice provide insights into natural killer cell maturation and memory. (2011) Riley, EM; Viney, ME

Wild mice provide insights into natural killer cell maturation and memory. (2011) Riley, Eleanor M; Viney, Mark E

Structures, targets and recent approaches in anti-leishmanial drug discovery and development. (2011) Seifert, Karin

In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani. (2011) Seifert, Karin; Munday, Jane; Syeda, Tahmina; Croft, Simon L

The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19). (2011) Shi, Jianguo; McIntosh, Richard S; Adame-Gallegos, Jaime; Dehal, Prabhjyot K; van Egmond, Marjolein; van de Winkel, Jan; Draper, Simon J; Forbes, Emily K; Corran, Patrick H; Holder, Anthony A; Woof, Jenny M; Pleass, Richard J

Antiplasmodial and cytotoxicity evaluation of 3-functionalized 2-azetidinone derivatives. (2011) Singh, Pardeep; Sachdeva, Shaveta; Raj, Raghu; Kumar, Vipan; Mahajan, Mohinder P; Nasser, Shereen; Vivas, Livia; Gut, Jiri; Rosenthal, Phillip J; Feng, Tzu-Shean; Chibale, Kelly

Indolone-N-oxide derivatives: in vitro activity against fresh clinical isolates of Plasmodium falciparum, stage specificity and in vitro interactions with established antimalarial drugs. (2011) Tahar, Rachida; Vivas, Livia; Basco, Leonardo; Thompson, Eloise; Ibrahim, Hany; Boyer, Jérémie; Nepveu, Françoise

Malaria elimination: how far can we go without a vaccine? (2011) Targett, G

Immune system development during early childhood in tropical Latin America: evidence for the age-dependent down regulation of the innate immune response. (2011) Teran, Rommy; Mitre, Edward; Vaca, Maritza; Erazo, Silvia; Oviedo, Gisela; Hübner, Marc P; Chico, Martha E; Mattapallil, Joseph J; Bickle, Quentin; Rodrigues, Laura C; Cooper, Philip J picture_as_pdf

2,4-diarylthiazole antiprion compounds as a novel structural class of antimalarial leads. (2011) Thompson, Mark J; Louth, Jennifer C; Little, Susan M; Chen, Beining; Coldham, Iain

Early detection of ovarian cancer in samples pre-diagnosis using CA125 and MALDI-MS peaks. (2011) Timms, John F; Menon, Usha; Devetyarov, Dmitry; Tiss, Ali; Camuzeaux, Stephane; McCurrie, Katherine; Nouretdinov, Ilia; Burford, Brian; Smith, Celia; Gentry-Maharaj, Aleksandra; Hallett, Rachel; Ford, Jeremy; Luo, Zhiyuan; Vovk, Volodya; Gammerman, Alex; Cramer, Rainer; Jacobs, Ian

CD4+CD25+ regulatory cells contribute to the regulation of colonic Th2 granulomatous pathology caused by schistosome infection. (2011) Turner, Joseph D; Jenkins, Gavin R; Hogg, Karen G; Aynsley, Sarah A; Paveley, Ross A; Cook, Peter C; Coles, Mark C; Mountford, Adrian P picture_as_pdf

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. (2011) Tweyongyere, Robert; Mawa, Patrice A; Kihembo, Macklyn; Jones, Frances M; Webb, Emily L; Cose, Stephen; Dunne, David W; Vennervald, Birgitte J; Elliott, Alison M

Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection. (2011) Villegas-Mendez, Ana; de Souza, J Brian; Murungi, Linda; Hafalla, Julius CR; Shaw, Tovah N; Greig, Rachel; Riley, Eleanor M; Couper, Kevin N

Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial. (2011) Webb, Emily L; Mawa, Patrice A; Ndibazza, Juliet; Kizito, Dennison; Namatovu, Alice; Kyosiimire-Lugemwa, Jacqueline; Nanteza, Bridget; Nampijja, Margaret; Muhangi, Lawrence; Woodburn, Patrick W; Akurut, Hellen; Mpairwe, Harriet; Akello, Miriam; Lyadda, Nancy; Bukusuba, Joseph; Kihembo, Macklyn; Kizza, Moses; Kizindo, Robert; Nabulime, Juliet; Ameke, Christine; Namujju, Proscovia B; Tweyongyere, Robert; Muwanga, Moses; Whitworth, James AG; Elliott, Alison M

Short-lived IFN-γ effector responses, but long-lived IL-10 memory responses, to malaria in an area of low malaria endemicity. (2011) Wipasa, Jiraprapa; Okell, Lucy; Sakkhachornphop, Supachai; Suphavilai, Chaisuree; Chawansuntati, Kriangkrai; Liewsaree, Witaya; Hafalla, Julius CR; Riley, Eleanor M

Immunization status of children with HIV: failure to protect a vulnerable population. (2011) Zinna, Ss; Bamford, A; Cunnington, A; Kampmann, B; Lyall, Egh; Menson, E; Heath, Pt

A research agenda for malaria eradication: basic science and enabling technologies. (2011) malERA Consultative Group on Basic Science and Enabling Technolo

Conference or Workshop Item

Single Nucleotide Polymorphisms in the Toll-Like Receptor 3 and CD44 Genes Are Associated with Persistence of Vaccine-Induced Immunity to the Serogroup C Meningococcal Conjugate Vaccine. (2011) Moore, CE; Hennig, BJ; Perrett, KP; Hoe, JC; Lee, SJ; Fletcher, H; Brocklebank, D; O'Connor, D; Snape, MD; Hall, AJ; Segal, S; Hill, AVS; Pollard, AJ

Th1/Th17 cell induction following vaccination with the novel tuberculosis vaccine MVA85A and their role in Mycobacterium tuberculosis challenge CD4 T cell response to MVA85A vaccination against Mycobacterium tuberculosis in healthy HIV-infected adults SO IMMUNOLOGY CT Annual Congress of the British-Society-for-Immunology CY DEC 05-08, 2011 CL Liverpool, ENGLAND SP British Soc Immunol. (2011) Griffiths, K; Stylianou, E; Poyntz, H; Betts, G; Fletcher, H; McShane, H; Beveridge, N; Minassian, A; Rowland, R; Poulton, I; Satti, I; Harris, S; Poyntz, H; Hamill, M; Griffiths, K; Sander, C; Ambrozak, D; Price, D; Hill, B; Casazza, J; Douek, D; Koup, R; Roederer, M; Winston, A; Ross, J; Sherrad, J; Rooney, G; Williams, N; Lawrie, A; Fletcher, H; Pathan, A; McShane, H

The Regulation of Interleukin 10 and Interleukin 12 in Macrophages. (2011) Howes, A; Wu, XM; Zhao, JW; Saraiva, M; Bancroft, GJ; O'Garra, A

In vitro screening of selected medicinal plants against Schistosoma mansoni larvae. (2011) Karamustafa, SD; Mansour, N; Bickle, Q; Tasdemir, D

In vitro effect of Myrrh extracts on the viability of Schistosoma mansoni larvae. (2011) Karamustafa, SD; Mansour, N; Demirci, B; Ankli, A; Baser, KHC; Bickle, Q; Tasdemir, D

The roles of haemoglobin S, haemoglobin C and alpha-thalassaemia in the development of acquired humoral immunity against malaria. (2011) Kreuel, B; Verra, F; Adjei, S; Ehmen, C; Ayim-Akonor, M; Kobbe, R; Kreuzberg, C; Drakeley, C; May, J

Development and evaluation of simplified molecular diagnostic devices for malaria. (2011) Mens, P; de Bes, L; Moers, A; Hallett, R; Verweij, J; Overmeir, C; Leeflang, M; van Amerongen, A; Tinto, H; Schallig, H

Thesis

`Eschericha coli' K1 interactions with human brain microvascular endothelial cells, a primary step in the development of neonatal meningitis. (2011) Loh, Lip Nam

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New Research Institute Combats Infectious Diseases Globally - 16 December 2011. (2011) UNSPECIFIED audio_file