LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Immunology and Infection (-2019) (972)

Dept of Pathogen Molecular Biology (-2019) (1192) Month Authors/Creators Item Type Full Text

Bibliographic data only

The Hidden Genomics of Chlamydia trachomatis. (2017) Hadfield, James; Bénard, Angèle; Domman, Daryl; Thomson, Nicholas

Integrated view of Vibrio cholerae in the Americas. (2017) Domman, Daryl; Quilici, Marie-Laure; Dorman, Matthew J; Njamkepo, Elisabeth; Mutreja, Ankur; Mather, Alison E; Delgado, Gabriella; Morales-Espinosa, Rosario; Grimont, Patrick AD; Lizárraga-Partida, Marcial Leonardo; Bouchier, Christiane; Aanensen, David M; Kuri-Morales, Pablo; Tarr, Cheryl L; Dougan, Gordon; Parkhill, Julian; Campos, Josefina; Cravioto, Alejandro; Weill, François-Xavier; Thomson, Nicholas R

Genomic history of the seventh pandemic of cholera in Africa. (2017) Weill, François-Xavier; Domman, Daryl; Njamkepo, Elisabeth; Tarr, Cheryl; Rauzier, Jean; Fawal, Nizar; Keddy, Karen H; Salje, Henrik; Moore, Sandra; Mukhopadhyay, Asish K; Bercion, Raymond; Luquero, Francisco J; Ngandjio, Antoinette; Dosso, Mireille; Monakhova, Elena; Garin, Benoit; Bouchier, Christiane; Pazzani, Carlo; Mutreja, Ankur; Grunow, Roland; Sidikou, Fati; Bonte, Laurence; Breurec, Sébastien; Damian, Maria; Njanpop-Lafourcade, Berthe-Marie; Sapriel, Guillaume; Page, Anne-Laure; Hamze, Monzer; Henkens, Myriam; Chowdhury, Goutam; Mengel, Martin; Koeck, Jean-Louis; Fournier, Jean-Michel; Dougan, Gordon; Grimont, Patrick AD; Parkhill, Julian; Holt, Kathryn E; Piarroux, Renaud; Ramamurthy, Thandavarayan; Quilici, Marie-Laure; Thomson, Nicholas R

The role of the red blood cell in host defence against falciparum malaria: an expanding repertoire of evolutionary alterations. (2017) Goheen, Morgan M; Campino, Susana; Cerami, Carla

Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity. (2017) Vanaerschot, Manu; Lucantoni, Leonardo; Li, Tao; Combrinck, Jill M; Ruecker, Andrea; Kumar, TR Santha; Rubiano, Kelly; Ferreira, Pedro E; Siciliano, Giulia; Gulati, Sonia; Henrich, Philipp P; Ng, Caroline L; Murithi, James M; Corey, Victoria C; Duffy, Sandra; Lieberman, Ori J; Veiga, M Isabel; Sinden, Robert E; Alano, Pietro; Delves, Michael J; Lee Sim, Kim; Winzeler, Elizabeth A; Egan, Timothy J; Hoffman, Stephen L; Avery, Vicky M; Fidock, David A

Single nucleotide polymorphisms in efflux pumps genes in extensively drug resistant Mycobacterium tuberculosis isolates from Pakistan. (2017) Kanji, Akbar; Hasan, Rumina; Ali, Asho; Zaver, Ambreen; Zhang, Ying; Imtiaz, Kehkashan; Shi, Wanliang; Clark, Taane G; McNerney, Ruth; Phelan, Jody; Rao, Shoaib; Shafiq, Samreen; Hasan, Zahra

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. (2017) Leven, Michael; Knaab, Tanja C; Held, Jana; Duffy, Sandra; Meister, Stephan; Fischli, Christoph; Meitzner, Diane; Lehmann, Ursula; Lungerich, Beate; Kuna, Krystina; Stahlke, Petra; Delves, Michael J; Buchholz, Mirko; Winzeler, Elizabeth A; Avery, Vicky M; Mordmüller, Benjamin; Wittlin, Sergio; Kurz, Thomas

Reply to van der Pluijm et al., "Antimalarial Resistance Unlikely To Explain U.K. Artemether-Lumefantrine Failures". (2017) Sutherland, Colin J

The midgut microbiota plays an essential role in sand fly vector competence for Leishmania major. (2017) Louradour, Isabelle; Monteiro, Carolina Cunha; Inbar, Ehud; Ghosh, Kashinath; Merkhofer, Richard; Lawyer, Phillip; Paun, Andrea; Smelkinson, Margery; Secundino, Nagila; Lewis, Michael; Erram, Dinesh; Zurek, Ludek; Sacks, David

Reply to Plucinski et al., "Interpreting Data from Passive Surveillance of Antimalarial Treatment Failures". (2017) Sutherland, Colin J; Gkrania-Klotsas, Effrossyni; Chiodini, Peter L

Diagnostic accuracy of the Xpert® MTB/RIF cycle threshold level to predict smear positivity: a meta-analysis. (2017) Lange, B; Khan, P; Kalmambetova, G; Al-Darraji, HA; Alland, D; Antonenka, U; Brown, T; Balcells, ME; Blakemore, R; Denkinger, CM; Dheda, K; Hoffmann, H; Kadyrov, A; Lemaitre, N; Miller, MB; Nikolayevskyy, V; Ntinginya, EN; Ozkutuk, N; Palacios, JJ; Popowitch, EB; Porcel, JM; Teo, J; Theron, G; Kranzer, K

Evidence of cross-stage CD8+ T cell epitopes in malaria pre-erythrocytic and blood stage infections. (2017) Müller, K; Gibbins, MP; Matuschewski, K; Hafalla, JCR

Pregnant Women: An Overlooked Asset to Plasmodium falciparum Malaria Elimination Campaigns? (2017) Gonçalves, Bronner P; Walker, Patrick G; Cairns, Matthew; Tiono, Alfred B; Bousema, Teun; Drakeley, Chris

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis. (2017) Dheda, Keertan; Gumbo, Tawanda; Maartens, Gary; Dooley, Kelly E; McNerney, Ruth; Murray, Megan; Furin, Jennifer; Nardell, Edward A; London, Leslie; Lessem, Erica; Theron, Grant; van Helden, Paul; Niemann, Stefan; Merker, Matthias; Dowdy, David; Van Rie, Annelies; Siu, Gilman KH; Pasipanodya, Jotam G; Rodrigues, Camilla; Clark, Taane G; Sirgel, Frik A; Esmail, Aliasgar; Lin, Hsien-Ho; Atre, Sachin R; Schaaf, H Simon; Chang, Kwok Chiu; Lange, Christoph; Nahid, Payam; Udwadia, Zarir F; Horsburgh, C Robert; Churchyard, Gavin J; Menzies, Dick; Hesseling, Anneke C; Nuermberger, Eric; McIlleron, Helen; Fennelly, Kevin P; Goemaere, Eric; Jaramillo, Ernesto; Low, Marcus; Jara, Carolina Morán; Padayatchi, Nesri; Warren, Robin M

Determinants of Malaria Transmission at the Population Level. (2017) Bousema, Teun; Drakeley, Chris

Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study. (2017) Dheda, Keertan; Limberis, Jason D; Pietersen, Elize; Phelan, Jody; Esmail, Aliasgar; Lesosky, Maia; Fennelly, Kevin P; Te Riele, Julian; Mastrapa, Barbara; Streicher, Elizabeth M; Dolby, Tania; Abdallah, Abdallah M; Ben-Rached, Fathia; Simpson, John; Smith, Liezel; Gumbo, Tawanda; van Helden, Paul; Sirgel, Frederick A; McNerney, Ruth; Theron, Grant; Pain, Arnab; Clark, Taane G; Warren, Robin M

Type I Interferon in Malaria: A Balancing Act. (2017) Mooney, Jason Paul; Wassmer, Samuel Crocodile; Hafalla, Julius Clemence

Correction for Cairns et al., "Comparative Genome Analysis and Global Phylogeny of the Toxin Variant Clostridium difficile PCR Ribotype 017 Reveals the Evolution of Two Independent Sublineages". (2017) Cairns, MD; Preston, MD; Hall, CL; Gerding, DN; Hawkey, PM; Kato, H; Kim, H; Kuijper, EJ; Lawley, TD; Pituch, H; Reid, S; Kullin, B; Riley, TV; Solomon, K; Tsai, PJ; Weese, JS; Stabler, RA; Wren, BW

Human Immunology of Tuberculosis. (2017) Scriba, Thomas J; Coussens, Anna K; Fletcher, Helen A

Public

Mycoplasma genitalium: whole genome sequence analysis, recombination and population structure. (2017) Fookes, Maria C; Hadfield, James; Harris, Simon; Parmar, Surendra; Unemo, Magnus; Jensen, Jørgen S; Thomson, Nicholas R

Diagnosing tuberculosis in hospitalized HIV-infected individuals who cannot produce sputum: is urine lipoarabinomannan testing the answer? (2017) Sabur, Natasha F; Esmail, Aliasgar; Brar, Mantaj S; Dheda, Keertan

Within-host evolution of Enterococcus faecium during longitudinal carriage and transition to bloodstream infection in immunocompromised patients. (2017) Moradigaravand, Danesh; Gouliouris, Theodore; Blane, Beth; Naydenova, Plamena; Ludden, Catherine; Crawley, Charles; Brown, Nicholas M; Török, M Estée; Parkhill, Julian; Peacock, Sharon J

Detecting Gametocytes: How Sensitive Is Sensible? (2017) Meerstein-Kessel, Lisette; Bousema, Teun; Stone, Will

Cyclic nucleotide signalling in malaria parasites. (2017) Baker, David A; Drought, Laura G; Flueck, Christian; Nofal, Stephanie D; Patel, Avnish; Penzo, Maria; Walker, Eloise M

Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Harris, Andy; Murdan, Sudaxshina; Croft, Simon L

Increased activated memory B-cells in the peripheral blood of patients with erythema nodosum leprosum reactions. (2017) Negera, Edessa; Walker, Stephen L; Bekele, Yonas; Dockrell, Hazel M; Lockwood, Diana N

A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line. (2017) Benavente, Ernest Diez; de Sessions, Paola Florez; Moon, Robert W; Grainger, Munira; Holder, Anthony A; Blackman, Michael J; Roper, Cally; Drakeley, Christopher J; Pain, Arnab; Sutherland, Colin J; Hibberd, Martin L; Campino, Susana; Clark, Taane G

Prevalence and persistence of Listeria monocytogenes in premises and products of small food business operators in Northern Ireland. (2017) Madden, Robert H; Hutchison, Mike; Jordan, Kieran; Pennone, Vincenzo; Gundogdu, Ozan; Corcionivoschi, Nicolae

Zoonotic Transfer of Clostridium difficile Harboring Antimicrobial Resistance between Farm Animals and Humans. (2017) Knetsch, CW; Kumar, N; Forster, SC; Connor, TR; Browne, HP; Harmanus, C; Sanders, IM; Harris, SR; Turner, L; Morris, T; Perry, M; Miyajima, F; Roberts, P; Pirmohamed, M; Songer, JG; Weese, JS; Indra, A; Corver, J; Rupnik, M; Wren, BW; Riley, TV; Kuijper, EJ; Lawley, TD

An in vitro assay to measure antibody-mediated inhibition of P. berghei sporozoite invasion against P. falciparum antigens. (2017) Rodríguez-Galán, Ana; Salman, Ahmed M; Bowyer, Georgina; Collins, Katharine A; Longley, Rhea J; Brod, Florian; Ulaszewska, Marta; Ewer, Katie J; Janse, Chris J; Khan, Shahid M; Hafalla, Julius C; Hill, Adrian VS; Spencer, Alexandra J

Use of Proteins Identified through a Functional Genomic Screen To Develop a Protein Subunit Vaccine That Provides Significant Protection against Virulent Streptococcus suis in Pigs. (2017) Brockmeier, Susan L; Loving, Crystal L; Nicholson, Tracy L; Wang, Jinhong; Peters, Sarah E; Weinert, Lucy; Chaudhuri, Roy; Seilly, David J; Langford, Paul R; Rycroft, Andrew; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W

The bile salt sodium taurocholate induces Campylobacter jejuni outer membrane vesicle production and increases OMV-associated proteolytic activity. (2017) Elmi, Abdi; Dorey, Amber; Watson, Eleanor; Jagatia, Heena; Inglis, Neil F; Gundogdu, Ozan; Bajaj-Elliott, Mona; Wren, Brendan W; Smith, David GE; Dorrell, Nick

Tissue-specific cellular immune responses to malaria pre-erythrocytic stages. (2017) Silvie, Olivier; Amino, Rogerio; Hafalla, Julius Clemence

In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial. (2017) Basilico, Nicoletta; Parapini, Silvia; Sparatore, Anna; Romeo, Sergio; Misiano, Paola; Vivas, Livia; Yardley, Vanessa; Croft, Simon L; Habluetzel, Annette; Lucantoni, Leonardo; Renia, Laurent; Russell, Bruce; Suwanarusk, Rossarin; Nosten, Francois; Dondio, Giulio; Bigogno, Chiara; Jabes, Daniela; Taramelli, Donatella

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis. (2017) Miotto, Paolo; Tessema, Belay; Tagliani, Elisa; Chindelevitch, Leonid; Starks, Angela M; Emerson, Claudia; Hanna, Debra; Kim, Peter S; Liwski, Richard; Zignol, Matteo; Gilpin, Christopher; Niemann, Stefan; Denkinger, Claudia M; Fleming, Joy; Warren, Robin M; Crook, Derrick; Posey, James; Gagneux, Sebastien; Hoffner, Sven; Rodrigues, Camilla; Comas, Iñaki; Engelthaler, David M; Murray, Megan; Alland, David; Rigouts, Leen; Lange, Christoph; Dheda, Keertan; Hasan, Rumina; Ranganathan, Uma Devi K; McNerney, Ruth; Ezewudo, Matthew; Cirillo, Daniela M; Schito, Marco; Köser, Claudio U; Rodwell, Timothy C

Genetic markers of artemisinin resistance in Plasmodium spp. parasites. (2017) Sutherland, Colin J

Macrophage-Microbe Interactions: Lessons from the Zebrafish Model. (2017) Yoshida, Nagisa; Frickel, Eva-Maria; Mostowy, Serge

SUMOylation of human septins is critical for septin filament bundling and cytokinesis. (2017) Ribet, David; Boscaini, Serena; Cauvin, Clothilde; Siguier, Martin; Mostowy, Serge; Echard, Arnaud; Cossart, Pascale

malERA: An updated research agenda for malaria elimination and eradication. (2017) Rabinovich, Regina N; Drakeley, Chris; Djimde, Abdoulaye A; Hall, B Fenton; Hay, Simon I; Hemingway, Janet; Kaslow, David C; Noor, Abdisalan; Okumu, Fredros; Steketee, Richard; Tanner, Marcel; Wells, Timothy NC; Whittaker, Maxine A; Winzeler, Elizabeth A; Wirth, Dyann F; Whitfield, Kate; Alonso, Pedro L

Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot. (2017) Sallah, N; Carstensen, T; Wakeham, K; Bagni, R; Labo, N; Pollard, MO; Gurdasani, D; Ekoru, K; Pomilla, C; Young, EH; Fatumo, S; Asiki, G; Kamali, A; Sandhu, M; Kellam, P; Whitby, D; Barroso, I; Newton, R

Use of QuantiFERON®-TB Gold in-tube culture supernatants for measurement of antibody responses. (2017) Kimuda, Simon G; Andia-Biraro, Irene; Egesa, Moses; Bagaya, Bernard S; Raynes, John G; Levin, Jonathan; Elliott, Alison M; Cose, Stephen

Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells. (2017) Lee, Pamela P; Lobato-Márquez, Damián; Pramanik, Nayani; Sirianni, Andrea; Daza-Cajigal, Vanessa; Rivers, Elizabeth; Cavazza, Alessia; Bouma, Gerben; Moulding, Dale; Hultenby, Kjell; Westerberg, Lisa S; Hollinshead, Michael; Lau, Yu-Lung; Burns, Siobhan O; Mostowy, Serge; Bajaj-Elliott, Mona; Thrasher, Adrian J

Interaction between a Unique Minor Protein and a Major Capsid Protein of Bluetongue Virus Controls Virus Infectivity. (2017) Matsuo, Eiko; Yamazaki, Kiyoshi; Tsuruta, Hiroki; Roy, Polly

Antimicrobial resistant <i>Klebsiella pneumoniae</i> carriage and infection in specialized geriatric care wards linked to acquisition in the referring hospital. (2017) Gorrie, Claire L; Mirceta, Mirjana; Wick, Ryan R; Judd, Louise M; Wyres, Kelly L; Thomson, Nicholas R; Strugnell, Richard A; Pratt, Nigel F; Garlick, Jill S; Watson, Kerrie M; Hunter, Peter C; McGloughlin, Steve A; Spelman, Denis W; Jenney, Adam WJ; Holt, Kathryn E

Mechanical force induces mitochondrial fission. (2017) Helle, Sebastian Carsten Johannes; Feng, Qian; Aebersold, Mathias J; Hirt, Luca; Grüter, Raphael R; Vahid, Afshin; Sirianni, Andrea; Mostowy, Serge; Snedeker, Jess G; Šarić, Anđela; Idema, Timon; Zambelli, Tomaso; Kornmann, Benoît

To what extent do structural changes in catalytic metal sites affect enzyme function? (2017) Valasatava, Yana; Rosato, Antonio; Furnham, Nicholas; Thornton, Janet M; Andreini, Claudia

Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of Kenya. (2017) Beshir, Khalid B; Sepúlveda, Nuno; Bharmal, Jameel; Robinson, Ailie; Mwanguzi, Julian; Busula, Annette Obukosia; de Boer, Jetske Gudrun; Sutherland, Colin; Cunningham, Jane; Hopkins, Heidi

Corrigendum to "Genetic diversity of next generation antimalarial targets: A baseline for drug resistance surveillance programmes" [Int. J. Parasitol. Drugs and Drug Resist. 7 (2017) 174-180]. (2017) Gomes, Ana Rita; Ravenhall, Matt; Benavente, Ernest Diez; Talman, Arthur; Sutherland, Colin; Roper, Cally; Clark, Taane G; Campino, Susana

Prospective cohort study to investigate the burden and transmission of acute gastroenteritis in care homes: a study protocol. (2017) Inns, Thomas; Pulawska-Czub, Anna; Harris, John P; Vivancos, Roberto; Read, Jonathan M; Beeching, Nicholas J; Allen, David J; Iturriza-Gomara, Miren; O'Brien, Sarah J

Residual malaria transmission dynamics varies across The Gambia despite high coverage of control interventions. (2017) Mwesigwa, Julia; Achan, Jane; Di Tanna, Gian Luca; Affara, Muna; Jawara, Musa; Worwui, Archibald; Hamid-Adiamoh, Majidah; Kanuteh, Fatoumatta; Ceesay, Sainey; Bousema, Teun; Drakeley, Chris; Grietens, Koen Peeters; Lindsay, Steve W; Van Geertruyden, Jean-Pierre; D'Alessandro, Umberto

Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites. (2017) Ribeiro, António JM; Holliday, Gemma L; Furnham, Nicholas; Tyzack, Jonathan D; Ferris, Katherine; Thornton, Janet M

Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017). (2017) Daher, Jana; Vijh, Rohit; Linthwaite, Blake; Dave, Sailly; Kim, John; Dheda, Keertan; Peter, Trevor; Pai, Nitika Pant

Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole. (2017) Campos, Mônica C; Phelan, Jody; Francisco, Amanda F; Taylor, Martin C; Lewis, Michael D; Pain, Arnab; Clark, Taane G; Kelly, John M

Frequent Undetected Ward-Based Methicillin-Resistant Staphylococcus aureus Transmission Linked to Patient Sharing Between Hospitals. (2017) Tosas Auguet, Olga; Stabler, Richard A; Betley, Jason; Preston, Mark D; Dhaliwal, Mandeep; Gaunt, Michael; Ioannou, Avgousta; Desai, Nergish; Karadag, Tacim; Batra, Rahul; Otter, Jonathan A; Marbach, Helene; Clark, Taane G; Edgeworth, Jonathan D

Longitudinal estimation of Plasmodium falciparum prevalence in relation to malaria prevention measures in six sub-Saharan African countries. (2017) Drakeley, Chris; Abdulla, Salim; Agnandji, Selidji Todagbe; Fernandes, José Francisco; Kremsner, Peter; Lell, Bertrand; Mewono, Ludovic; Bache, Bache Emmanuel; Mihayo, Michael Gabriel; Juma, Omar; Tanner, Marcel; Tahita, Marc Christian; Tinto, Halidou; Diallo, Salou; Lompo, Palpouguini; D'Alessandro, Umberto; Ogutu, Bernhards; Otieno, Lucas; Otieno, Solomon; Otieno, Walter; Oyieko, Janet; Asante, Kwaku Poku; Dery, Dominic Bon-Ereme; Adjei, George; Adeniji, Elisha; Atibilla, Dorcas; Owusu-Agyei, Seth; Greenwood, Brian; Gesase, Samwel; Lusingu, John; Mahende, Coline; Mongi, Robert; Segeja, Method; Adjei, Samuel; Agbenyega, Tsiri; Agyekum, Alex; Ansong, Daniel; Bawa, John Tanko; Boateng, Harry Owusu; Dandalo, Léonard; Escamilla, Veronica; Hoffman, Irving; Maenje, Peter; Martinson, Francis; Carter, Terrell; Leboulleux, Didier; Kaslow, David C; Usuf, Effua; Pirçon, Jean-Yves; Bahmanyar, Edith Roset

Single-virion sequencing of lamivudine-treated HBV populations reveal population evolution dynamics and demographic history. (2017) Zhu, Yuan O; Aw, Pauline PK; de Sessions, Paola Florez; Hong, Shuzhen; See, Lee Xian; Hong, Lewis Z; Wilm, Andreas; Li, Chen Hao; Hue, Stephane; Lim, Seng Gee; Nagarajan, Niranjan; Burkholder, William F; Hibberd, Martin

Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity. (2017) Gonçalves, Bronner P; Kapulu, Melissa C; Sawa, Patrick; Guelbéogo, Wamdaogo M; Tiono, Alfred B; Grignard, Lynn; Stone, Will; Hellewell, Joel; Lanke, Kjerstin; Bastiaens, Guido JH; Bradley, John; Nébié, Issa; Ngoi, Joyce M; Oriango, Robin; Mkabili, Dora; Nyaurah, Maureen; Midega, Janet; Wirth, Dyann F; Marsh, Kevin; Churcher, Thomas S; Bejon, Philip; Sirima, Sodiomon B; Drakeley, Chris; Bousema, Teun

Longitudinal genomic surveillance of MRSA in the UK reveals transmission patterns in hospitals and the community. (2017) Coll, Francesc; Harrison, Ewan M; Toleman, Michelle S; Reuter, Sandra; Raven, Kathy E; Blane, Beth; Palmer, Beverley; Kappeler, A Ruth M; Brown, Nicholas M; Török, M Estée; Parkhill, Julian; Peacock, Sharon J

Microbiome genetics underpins chemotherapy. (2017) Scott, Timothy A; Quintaneiro, Leonor M; Cabreiro, Filipe

Investigation of a Cluster of Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Transmission in a Community Setting. (2017) Toleman, Michelle S; Watkins, Emmeline R; Williams, Tom; Blane, Beth; Sadler, Belinda; Harrison, Ewan M; Coll, Francesc; Parkhill, Julian; Nazareth, Bernadette; Brown, Nicholas M; Peacock, Sharon J

Population-based analysis of ocular<i>Chlamydia trachomatis</i>in trachoma-endemic West African communities identifies genomic markers of disease severity. (2017) Last, AR; Pickering, H; Roberts, Ch; Coll, F; Phelan, J; Burr, SE; Cassama, E; Nabicassa, M; Seth-Smith, HMB; Hadfield, J; Cutcliffe, LT; Clarke, IN; Mabey, DCW; Bailey, RL; Clark, TG; Thomson, NR; Holland, MJ

Comparative assessment of An. gambiae and An. stephensi mosquitoes to determine transmission-reducing activity of antibodies against P. falciparum sexual stage antigens. (2017) Eldering, Maarten; Bompard, Anaïs; Miura, Kazutoyo; Stone, Will; Morlais, Isabelle; Cohuet, Anna; van Gemert, Geert-Jan; Brock, Patrick M; Rijpma, Sanna R; van de Vegte-Bolmer, Marga; Graumans, Wouter; Siebelink-Stoter, Rianne; Da, Dari F; Long, Carole A; Morin, Merribeth J; Sauerwein, Robert W; Churcher, Thomas S; Bousema, Teun

Diagnostics for Yaws Eradication: Insights From Direct Next-Generation Sequencing of Cutaneous Strains of Treponema pallidum. (2017) Marks, Michael; Fookes, Maria; Wagner, Josef; Butcher, Robert; Ghinai, Rosanna; Sokana, Oliver; Sarkodie, Yaw-Adu; Lukehart, Sheila A; Solomon, Anthony W; Mabey, David CW; Thomson, Nicholas

A recombinase polymerase amplification assay for rapid detection of Crimean-Congo Haemorrhagic fever Virus infection. (2017) Bonney, Laura C; Watson, Robert J; Afrough, Babak; Mullojonova, Manija; Dzhuraeva, Viktoriya; Tishkova, Farida; Hewson, Roger

Clinico-pathological features of erythema nodosum leprosum: A case-control study at ALERT hospital, Ethiopia. (2017) Negera, Edessa; Walker, Stephen L; Girma, Selfu; Doni, Shimelis N; Tsegaye, Degafe; Lambert, Saba M; Idriss, Munir H; Tsegay, Yohanis; Dockrell, Hazel M; Aseffa, Abraham; Lockwood, Diana N

A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance. (2017) Sheen, Patricia; Requena, David; Gushiken, Eduardo; Gilman, Robert H; Antiparra, Ricardo; Lucero, Bryan; Lizárraga, Pilar; Cieza, Basilio; Roncal, Elisa; Grandjean, Louis; Pain, Arnab; McNerney, Ruth; Clark, Taane G; Moore, David; Zimic, Mirko

Assay optimisation and technology transfer for multi-site immuno-monitoring in vaccine trials. (2017) Smith, Steven G; Harris, Stephanie A; Satti, Iman; Bryan, Donna; Walker, K Barry; Dockrell, Hazel M; McShane, Helen; Ho, Mei Mei

T-cell regulation in Erythema Nodosum Leprosum. (2017) Negera, Edessa; Walker, Stephen L; Bobosha, Kidist; Howe, Rawleigh; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

Leishmania and other intracellular pathogens: selectivity, drug distribution and PK-PD. (2017) Croft, Simon L

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development. (2017) Kaufmann, Stefan HE; Dockrell, Hazel M; Drager, Nick; Ho, Mei Mei; McShane, Helen; Neyrolles, Olivier; Ottenhoff, Tom HM; Patel, Brij; Roordink, Danielle; Spertini, François; Stenger, Steffen; Thole, Jelle; Verreck, Frank AW; Williams, Ann; TBVAC2020 Consortium

Prospective Surveillance and Rapid Whole-Genome Sequencing Detects Two Unsuspected Outbreaks of Carbapenemase-Producing Klebsiella pneumoniae in a UK Teaching Hospital. (2017) Torok, Estee; Brodrick, Hayley; Khokhar, Fahad; Blane, Beth; Polgarova, Petra; Brown, Joanne; Enoch, David; Brown, Nicholas; Summers, Charlotte; Preller, Jacobus; Thomson, Nick; Dougan, Gordon; Parkhill, Julian; Peacock, Sharon

Phylogenetic analysis of simian Plasmodium spp. infecting Anopheles balabacensis Baisas in Sabah, Malaysia. (2017) Chua, Tock H; Manin, Benny O; Daim, Sylvia; Vythilingam, Indra; Drakeley, Chris

Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance. (2017) Nakatani, Yoshio; Opel-Reading, Helen K; Merker, Matthias; Machado, Diana; Andres, Sönke; Kumar, S Siva; Moradigaravand, Danesh; Coll, Francesc; Perdigão, João; Portugal, Isabel; Schön, Thomas; Nair, Dina; Devi, KR Uma; Kohl, Thomas A; Beckert, Patrick; Clark, Taane G; Maphalala, Gugu; Khumalo, Derrick; Diel, Roland; Klaos, Kadri; Aung, Htin Lin; Cook, Gregory M; Parkhill, Julian; Peacock, Sharon J; Swaminathan, Soumya; Viveiros, Miguel; Niemann, Stefan; Krause, Kurt L; Köser, Claudio U

Complete Genome Sequence of a Porcine Epidemic Diarrhea Virus Isolated in Belgorod, Russia, in 2008. (2017) Strizhakova, Olga; Hanke, Dennis; Titov, Ilya; Blome, Sandra; Malogolovkin, Alexander

Completing bacterial genome assemblies with multiplex MinION sequencing. (2017) Wick, Ryan R; Judd, Louise M; Gorrie, Claire L; Holt, Kathryn E

Lessons learnt from imported cases and onward transmission of Lassa fever in Europe support broader management of viral haemorrhagic fevers. (2017) Hewson, Roger

Supporting surveillance capacity for antimicrobial resistance: Laboratory capacity strengthening for drug resistant infections in low and middle income countries. (2017) Seale, Anna C; Hutchison, Coll; Fernandes, Silke; Stoesser, Nicole; Kelly, Helen; Lowe, Brett; Turner, Paul; Hanson, Kara; Chandler, Clare IR; Goodman, Catherine; Stabler, Richard A; Scott, J Anthony G

Variability of Cutaneous Leishmaniasis Lesions Is Not Associated with Genetic Diversity of Leishmania tropica in Khyber Pakhtunkhwa Province of Pakistan. (2017) Khan, Nazma Habib; Llewellyn, Martin S; Schönian, Gabriele; Sutherland, Colin J

In Vitro Susceptibility to Closthioamide among Clinical and Reference Strains of Neisseria gonorrhoeae. (2017) Miari, Victoria F; Solanki, Priya; Hleba, Yonek; Stabler, Richard A; Heap, John T

Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology. (2017) Macdonald, Sarah E; Nolan, Matthew J; Harman, Kimberley; Boulton, Kay; Hume, David A; Tomley, Fiona M; Stabler, Richard A; Blake, Damer P

Marked variation in prevalence of malaria-protective human genetic polymorphisms across Uganda. (2017) Walakira, Andrew; Tukwasibwe, Stephen; Kiggundu, Moses; Verra, Federica; Kakeeto, Patrick; Ruhamyankaka, Emmanuel; Drakeley, Chris; Dorsey, Grant; Kamya, Moses R; Nsobya, Samuel L; Rosenthal, Philip J

Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations. (2017) Diez Benavente, Ernest; Florez de Sessions, Paola; Moon, Robert W; Holder, Anthony A; Blackman, Michael J; Roper, Cally; Drakeley, Christopher J; Pain, Arnab; Sutherland, Colin J; Hibberd, Martin L; Campino, Susana; Clark, Taane G

New Insight into the Pathogenesis of Erythema Nodosum Leprosum: The Role of Activated Memory T-Cells. (2017) Negera, Edessa; Bobosha, Kidist; Walker, Stephen L; Endale, Birtukan; Howe, Rawleigh; Aseffa, Abraham; Dockrell, Hazel M; Lockwood, Diana N

PlasmidTron: assembling the cause of phenotypes from NGS data. (2017) Page, Andrew J; Wailan, Alexander; Shao, Yan; Judge, Kim; Dougan, Gordon; Klemm, Elizabeth J; Thomson, Nicholas R; Keane, Jacqueline A

Comparative Genomic Analysis and In Vivo Modeling of Streptococcus pneumoniae ST3081 and ST618 Isolates Reveal Key Genetic and Phenotypic Differences Contributing to Clonal Replacement of Serotype 1 in The Gambia. (2017) Bricio-Moreno, Laura; Ebruke, Chinelo; Chaguza, Chrispin; Cornick, Jennifer; Kwambana-Adams, Brenda; Yang, Marie; Mackenzie, Grant; Wren, Brendan W; Everett, Dean; Antonio, Martin; Kadioglu, Aras

Epithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic. (2017) Entwistle, Lewis J; Pelly, Victoria S; Coomes, Stephanie M; Kannan, Yashaswini; Perez-Lloret, Jimena; Czieso, Stephanie; Silva Dos Santos, Mariana; MacRae, James I; Collinson, Lucy; Sesay, Abdul; Nikolov, Nikolay; Metidji, Amina; Helmby, Helena; Hui, David Y; Wilson, Mark S

What Have We Learnt about BCG Vaccination in the Last 20 Years? (2017) Dockrell, Hazel M; Smith, Steven G

Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial. (2017) Walk, Jona; Reuling, Isaie J; Behet, Marije C; Meerstein-Kessel, Lisette; Graumans, Wouter; van Gemert, Geert-Jan; Siebelink-Stoter, Rianne; van de Vegte-Bolmer, Marga; Janssen, Thorsten; Teelen, Karina; de Wilt, Johannes HW; de Mast, Quirijn; van der Ven, André J; Diez Benavente, Ernest; Campino, Susana; Clark, Taane G; Huynen, Martijn A; Hermsen, Cornelus C; Bijker, Else M; Scholzen, Anja; Sauerwein, Robert W

Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis. (2017) Gentekaki, Eleni; Curtis, Bruce A; Stairs, Courtney W; Klimeš, Vladimír; Eliáš, Marek; Salas-Leiva, Dayana E; Herman, Emily K; Eme, Laura; Arias, Maria C; Henrissat, Bernard; Hilliou, Frédérique; Klute, Mary J; Suga, Hiroshi; Malik, Shehre-Banoo; Pightling, Arthur W; Kolisko, Martin; Rachubinski, Richard A; Schlacht, Alexander; Soanes, Darren M; Tsaousis, Anastasios D; Archibald, John M; Ball, Steven G; Dacks, Joel B; Clark, C Graham; van der Giezen, Mark; Roger, Andrew J

Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility. (2017) Green, Judith L; Wall, Richard J; Vahokoski, Juha; Yusuf, Noor A; Ridzuan, Mohd A Mohd; Stanway, Rebecca R; Stock, Jessica; Knuepfer, Ellen; Brady, Declan; Martin, Stephen R; Howell, Steven A; Pires, Isa P; Moon, Robert W; Molloy, Justin E; Kursula, Inari; Tewari, Rita; Holder, Anthony A

Impact of the Mk VI SkinSuit on skin microbiota of terrestrial volunteers and an International Space Station-bound astronaut. (2017) Stabler, Richard A; Rosado, Helena; Doyle, Ronan; Negus, David; Carvil, Philip A; Kristjánsson, Juan G; Green, David A; Franco-Cendejas, Rafael; Davies, Cadi; Mogensen, Andreas; Scott, Jonathan; Taylor, Peter W

Understanding enzyme function evolution from a computational perspective. (2017) Tyzack, Jonathan D; Furnham, Nicholas; Sillitoe, Ian; Orengo, Christine M; Thornton, Janet M

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. (2017) Baker, David A; Stewart, Lindsay B; Large, Jonathan M; Bowyer, Paul W; Ansell, Keith H; Jiménez-Díaz, María B; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J; Bouloc, Nathalie S; Coombs, Peter J; Whalley, David; Harding, Denise J; Smiljanic-Hurley, Ela; Wheldon, Mary C; Walker, Eloise M; Dessens, Johannes T; Lafuente, María José; Sanz, Laura M; Gamo, Francisco-Javier; Ferrer, Santiago B; Hui, Raymond; Bousema, Teun; Angulo-Barturén, Iñigo; Merritt, Andy T; Croft, Simon L; Gutteridge, Winston E; Kettleborough, Catherine A; Osborne, Simon A

Evolution of mobile genetic element composition in an epidemic methicillin-resistant Staphylococcus aureus: temporal changes correlated with frequent loss and gain events. (2017) Jamrozy, Dorota; Coll, Francesc; Mather, Alison E; Harris, Simon R; Harrison, Ewan M; MacGowan, Alasdair; Karas, Andreas; Elston, Tony; Estée Török, M; Parkhill, Julian; Peacock, Sharon J

An untypeable enterotoxigenic Escherichia coli represents one of the dominant types causing human disease. (2017) Iguchi, Atsushi; von Mentzer, Astrid; Kikuchi, Taisei; Thomson, Nicholas R

Salmonella ubiquitination: ARIH1 enters the fray. (2017) Lobato-Márquez, Damián; Mostowy, Serge

Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence. (2017) Schallig, Henk Dfh; Tinto, Halidou; Sawa, Patrick; Kaur, Harparkash; Duparc, Stephan; Ishengoma, Deus S; Magnussen, Pascal; Alifrangis, Michael; Sutherland, Colin J

Comparison of the susceptibility of Plasmodium knowlesi and Plasmodium falciparum to antimalarial agents. (2017) van Schalkwyk, Donelly A; Moon, Robert W; Blasco, Benjamin; Sutherland, Colin J

Phosphoproteomic Analysis Reveals the Importance of Kinase Regulation During Orbivirus Infection. (2017) Mohl, Bjorn-Patrick; Emmott, Edward; Roy, Polly

Genome-wide profiling of humoral immunity and pathogen genes under selection identifies immune evasion tactics of Chlamydia trachomatis during ocular infection. (2017) Pickering, Harry; Teng, Andy; Faal, Nkoyo; Joof, Hassan; Makalo, Pateh; Cassama, Eunice; Nabicassa, Meno; Last, Anna R; Burr, Sarah E; Rowland-Jones, Sarah L; Thomson, Nicholas R; Roberts, Chrissy H; Mabey, David CW; Bailey, Robin L; Hayward, Richard D; de la Maza, Luis M; Holland, Martin J

Methods for ascertaining norovirus disease burdens. (2017) Allen, David J; Harris, John P

Methods for ascertaining norovirus disease burdens. (2017) Allen, David J; Harris, John P

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi. (2017) Brand, Stephen; Ko, Eun Jung; Viayna, Elisabet; Thompson, Stephen; Spinks, Daniel; Thomas, Michael; Sandberg, Lars; Francisco, Amanda F; Jayawardhana, Shiromani; Smith, Victoria C; Jansen, Chimed; De Rycker, Manu; Thomas, John; MacLean, Lorna; Osuna-Cabello, Maria; Riley, Jennifer; Scullion, Paul; Stojanovski, Laste; Simeons, Frederick RC; Epemolu, Ola; Shishikura, Yoko; Crouch, Sabrinia D; Bakshi, Tania S; Nixon, Christopher J; Reid, Iain H; Hill, Alan P; Underwood, Tim Z; Hindley, Sean J; Robinson, Sharon A; Kelly, John M; Fiandor, Jose M; Wyatt, Paul G; Marco, Maria; Miles, Timothy J; Read, Kevin D; Gilbert, Ian H

Biological factors that impinge on Chagas disease drug development. (2017) Francisco, Amanda F; Jayawardhana, Shiromani; Lewis, Michael D; Taylor, Martin C; Kelly, John M

Disparate subcellular location of putative sortase substrates in Clostridium difficile. (2017) Peltier, Johann; Shaw, Helen A; Wren, Brendan W; Fairweather, Neil F

Naturally acquired antibody response to Plasmodium falciparum describes heterogeneity in transmission on islands in Lake Victoria. (2017) Idris, Zulkarnain Md; Chan, Chim W; Kongere, James; Hall, Tom; Logedi, John; Gitaka, Jesse; Drakeley, Chris; Kaneko, Akira

Lipophilic conformationally constrained spiro carbocyclic 2,6-diketopiperazine-1-acetohydroxamic acid analogues as trypanocidal and leishmanicidal agents: An extended SAR study. (2017) Zoidis, Grigoris; Tsotinis, Andrew; Tsatsaroni, Alexandra; Taylor, Martin C; Kelly, John M; Efstathiou, Antonia; Smirlis, Despina; Fytas, George

Rapid replacement by non-vaccine pneumococcal serotypes may mitigate the impact of the pneumococcal conjugate vaccine on nasopharyngeal bacterial ecology. (2017) Kwambana-Adams, Brenda; Hanson, Blake; Worwui, Archibald; Agbla, Schadrac; Foster-Nyarko, Ebenezer; Ceesay, Fatima; Ebruke, Chinelo; Egere, Uzochukwu; Zhou, Yanjiao; Ndukum, Maze; Sodergren, Erica; Barer, Michael; Adegbola, Richard; Weinstock, George; Antonio, Martin

Pathogen imaging applications. (2017) Taylor, Martin C; Ward, Theresa H

Escherichia coli K1 utilizes host macropinocytic pathways for invasion of brain microvascular endothelial cells. (2017) Loh, Lip Nam; McCarthy, Elizabeth MC; Narang, Priyanka; Khan, Naveed A; Ward, Theresa H

Transcriptome and proteome analysis of Salmonella enterica serovar Typhimurium systemic infection of wild type and immune-deficient mice. (2017) Oshota, Olusegun; Conway, Max; Fookes, Maria; Schreiber, Fernanda; Chaudhuri, Roy R; Yu, Lu; Morgan, Fiona JE; Clare, Simon; Choudhary, Jyoti; Thomson, Nicholas R; Lio, Pietro; Maskell, Duncan J; Mastroeni, Pietro; Grant, Andrew J

Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs. (2017) Meredith, Emma Louise; Kumar, Ambika; Konno, Aya; Szular, Joanna; Alsford, Sam; Seifert, Karin; Horn, David; Wilkinson, Shane R

Elucidating virus entry using a tetracysteine-tagged virus. (2017) Mohl, Bjorn-Patrick; Roy, Polly

Genomic surveillance reveals low prevalence of livestock-associated methicillin-resistant Staphylococcus aureus in the East of England. (2017) Harrison, Ewan M; Coll, Francesc; Toleman, Michelle S; Blane, Beth; Brown, Nicholas M; Török, M Estee; Parkhill, Julian; Peacock, Sharon J

Mapping sulphadoxine-pyrimethamine-resistant Plasmodium falciparum malaria in infected humans and in parasite populations in Africa. (2017) Okell, Lucy C; Griffin, Jamie T; Roper, Cally

Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays. (2017) Reuling, Isaie J; Stone, Will JR; van de Vegte-Bolmer, Marga; van Gemert, Geert-Jan; Siebelink-Stoter, Rianne; Graumans, Wouter; Lanke, Kjerstin; Bousema, Teun; Sauerwein, Robert W

A longitudinal cohort study of malaria exposure and changing serostatus in a malaria endemic area of rural Tanzania. (2017) Simmons, Ryan A; Mboera, Leonard; Miranda, Marie Lynn; Morris, Alison; Stresman, Gillian; Turner, Elizabeth L; Kramer, Randall; Drakeley, Chris; O'Meara, Wendy P

Assessing gut microbiota perturbations during the early phase of infectious diarrhea in Vietnamese children. (2017) The, Hao Chung; Florez de Sessions, Paola; Jie, Song; Pham Thanh, Duy; Thompson, Corinne N; Nguyen Ngoc Minh, Chau; Chu, Collins Wenhan; Tran, Tuan-Anh; Thomson, Nicholas R; Thwaites, Guy E; Rabaa, Maia A; Hibberd, Martin; Baker, Stephen

Ceftazidime-avibactam has potent sterilizing activity against highly drug-resistant tuberculosis. (2017) Deshpande, Devyani; Srivastava, Shashikant; Chapagain, Moti; Magombedze, Gesham; Martin, Katherine R; Cirrincione, Kayle N; Lee, Pooi S; Koeuth, Thearith; Dheda, Keertan; Gumbo, Tawanda

Taxonomy of the order Mononegavirales: update 2017. (2017) Amarasinghe, Gaya K; Bào, Yīmíng; Basler, Christopher F; Bavari, Sina; Beer, Martin; Bejerman, Nicolás; Blasdell, Kim R; Bochnowski, Alisa; Briese, Thomas; Bukreyev, Alexander; Calisher, Charles H; Chandran, Kartik; Collins, Peter L; Dietzgen, Ralf G; Dolnik, Olga; Dürrwald, Ralf; Dye, John M; Easton, Andrew J; Ebihara, Hideki; Fang, Qi; Formenty, Pierre; Fouchier, Ron AM; Ghedin, Elodie; Harding, Robert M; Hewson, Roger; Higgins, Colleen M; Hong, Jian; Horie, Masayuki; James, Anthony P; Jiāng, Dàohóng; Kobinger, Gary P; Kondo, Hideki; Kurath, Gael; Lamb, Robert A; Lee, Benhur; Leroy, Eric M; Li, Ming; Maisner, Andrea; Mühlberger, Elke; Netesov, Sergey V; Nowotny, Norbert; Patterson, Jean L; Payne, Susan L; Paweska, Janusz T; Pearson, Michael N; Randall, Rick E; Revill, Peter A; Rima, Bertus K; Rota, Paul; Rubbenstroth, Dennis; Schwemmle, Martin; Smither, Sophie J; Song, Qisheng; Stone, David M; Takada, Ayato; Terregino, Calogero; Tesh, Robert B; Tomonaga, Keizo; Tordo, Noël; Towner, Jonathan S; Vasilakis, Nikos; Volchkov, Viktor E; Wahl-Jensen, Victoria; Walker, Peter J; Wang, Beibei; Wang, David; Wang, Fei; Wang, Lin-Fa; Werren, John H; Whitfield, Anna E; Yan, Zhichao; Ye, Gongyin; Kuhn, Jens H

Genome-wide diversity and differentiation in New World populations of the human malaria parasite Plasmodium vivax. (2017) de Oliveira, Thais C; Rodrigues, Priscila T; Menezes, Maria José; Gonçalves-Lopes, Raquel M; Bastos, Melissa S; Lima, Nathália F; Barbosa, Susana; Gerber, Alexandra L; Loss de Morais, Guilherme; Berná, Luisa; Phelan, Jody; Robello, Carlos; de Vasconcelos, Ana Tereza R; Alves, João Marcelo P; Ferreira, Marcelo U

A comparison of the conditional inference survival forest model to random survival forests based on a simulation study as well as on two applications with time-to-event data. (2017) Nasejje, Justine B; Mwambi, Henry; Dheda, Keertan; Lesosky, Maia

Multiplication rate variation in the human malaria parasite Plasmodium falciparum. (2017) Murray, Lee; Stewart, Lindsay B; Tarr, Sarah J; Ahouidi, Ambroise D; Diakite, Mahamadou; Amambua-Ngwa, Alfred; Conway, David J

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei. (2017) Stortz, Jennifer A; Serafim, Tiago D; Alsford, Sam; Wilkes, Jonathan; Fernandez-Cortes, Fernando; Hamilton, Graham; Briggs, Emma; Lemgruber, Leandro; Horn, David; Mottram, Jeremy C; McCulloch, Richard

Molecular epidemiology of Klebsiella pneumoniae invasive infections over a decade at Kilifi County Hospital in Kenya. (2017) Henson, Sonal P; Boinett, Christine J; Ellington, Matthew J; Kagia, Ngure; Mwarumba, Salim; Nyongesa, Sammy; Mturi, Neema; Kariuki, Samuel; Scott, J Anthony G; Thomson, Nicholas R; Morpeth, Susan C

Comment on "Effect of biofilm formation by clinical isolates of Helicobacter pylori on the efflux-mediated resistance to commonly used antibiotics". (2017) Kazakos, Evangelos I; Dorrell, Nick; Polyzos, Stergios A; Deretzi, Georgia; Kountouras, Jannis

Disease severity in patients with visceral leishmaniasis is not altered by co-infection with intestinal parasites. (2017) Tajebe, Fitsumbrhan; Getahun, Mulusew; Adem, Emebet; Hailu, Asrat; Lemma, Mulualem; Fikre, Helina; Raynes, John; Tamiru, Aschalew; Mulugeta, Zemenay; Diro, Ermias; Toulza, Frederic; Shkedy, Ziv; Ayele, Tadesse; Modolell, Manuel; Munder, Markus; Müller, Ingrid; Takele, Yegnasew; Kropf, Pascale

Brucella Genetic Variability in Wildlife Marine Mammals Populations Relates to Host Preference and Ocean Distribution. (2017) Suárez-Esquivel, Marcela; Baker, Kate S; Ruiz-Villalobos, Nazareth; Hernández-Mora, Gabriela; Barquero-Calvo, Elías; González-Barrientos, Rocío; Castillo-Zeledón, Amanda; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Cloeckaert, Axel; Chaves-Olarte, Esteban; Thomson, Nicholas R; Moreno, Edgardo; Guzmán-Verri, Caterina

A dual colour fluorescence in situ hybridization (FISH) assay for identifying the zoonotic malaria parasite Plasmodium knowlesi with a potential application for the specific diagnosis of knowlesi malaria in peripheral-level laboratories of Southeast Asia. (2017) Shah, Jyotsna; Poruri, Akhila; Mark, Olivia; Khadilka, Urmila; Mohring, Franziska; Moon, Robert W; Ramasamy, Ranjan

Evaluation of electric nets as means to sample mosquito vectors host-seeking on humans and primates. (2017) Hawkes, Frances; Manin, Benny Obrain; Ng, Sui Han; Torr, Stephen J; Drakeley, Chris; Chua, Tock H; Ferguson, Heather M

Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients. (2017) Gorrie, Claire L; Mirceta, Mirjana; Wick, Ryan R; Edwards, David J; Thomson, Nicholas R; Strugnell, Richard A; Pratt, Nigel F; Garlick, Jill S; Watson, Kerri M; Pilcher, David V; McGloughlin, Steve A; Spelman, Denis W; Jenney, Adam WJ; Holt, Kathryn E

The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014. (2017) Brennan, Michael J; Tanner, Rachel; Morris, Sheldon; Scriba, Thomas J; Achkar, Jacqueline M; Zelmer, Andrea; Hokey, David A; Izzo, Angelo; Sharpe, Sally; Williams, Ann; Penn-Nicholson, Adam; Erasmus, Mzwandile; Stylianou, Elena; Hoft, Daniel F; McShane, Helen; Fletcher, Helen A

Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia. (2017) Sengstake, Sarah; Bergval, Indra L; Schuitema, Anja R; de Beer, Jessica L; Phelan, Jody; de Zwaan, Rina; Clark, Taane G; van Soolingen, Dick; Anthony, Richard M

Galleria mellonella is low cost and suitable surrogate host for studying virulence of human pathogenic Vibrio cholerae. (2017) Bokhari, Habib; Ali, Amjad; Noreen, Zobia; Thomson, Nicholas; Wren, Brendan W

Completing bacterial genome assemblies with multiplex MinION sequencing. (2017) Wick, Ryan R; Judd, Louise M; Gorrie, Claire L; Holt, Kathryn E

The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes. (2017) Collins, Christine R; Hackett, Fiona; Atid, Jonathan; Tan, Michele Ser Ying; Blackman, Michael J

Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei. (2017) Macedo, Juan P; Currier, Rachel B; Wirdnam, Corina; Horn, David; Alsford, Sam; Rentsch, Doris

Sharing of carbapenemase-encoding plasmids between Enterobacteriaceae in UK sewage uncovered by MinION sequencing. (2017) Ludden, Catherine; Reuter, Sandra; Judge, Kim; Gouliouris, Theodore; Blane, Beth; Coll, Francesc; Naydenova, Plamena; Hunt, Martin; Tracey, Alan; Hopkins, Katie L; Brown, Nicholas M; Woodford, Neil; Parkhill, Julian; Peacock, Sharon J

Rotavirus Genomic RNA Complex Forms via Specific RNA-RNA Interactions: Disruption of RNA Complex Inhibits Virus Infectivity. (2017) Fajardo, Teodoro; Sung, Po-Yu; Celma, Cristina C; Roy, Polly

Protective efficacy of multivalent replication-abortive vaccine strains in horses against African horse sickness virus challenge. (2017) Lulla, Valeria; Losada, Andres; Lecollinet, Sylvie; Kerviel, Adeline; Lilin, Thomas; Sailleau, Corinne; Beck, Cecile; Zientara, Stephan; Roy, Polly

The emerging GII.P16-GII.4 Sydney 2012 norovirus lineage is circulating worldwide, arose by late-2014 and contains polymerase changes that may increase virus transmission. (2017) Ruis, Christopher; Roy, Sunando; Brown, Julianne R; Allen, David J; Goldstein, Richard A; Breuer, Judith

Generating conditional gene knockouts in Plasmodium - a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9. (2017) Knuepfer, Ellen; Napiorkowska, Marta; van Ooij, Christiaan; Holder, Anthony A

Making HIV testing work at the point of care in South Africa: a qualitative study of diagnostic practices. (2017) Engel, Nora; Davids, Malika; Blankvoort, Nadine; Dheda, Keertan; Pant Pai, Nitika; Pai, Madhukar

G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon. (2017) Dombrowski, Jamille G; Souza, Rodrigo M; Curry, Jonathan; Hinton, Laura; Silva, Natercia RM; Grignard, Lynn; Gonçalves, Ligia A; Gomes, Ana Rita; Epiphanio, Sabrina; Drakeley, Chris; Huggett, Jim; Clark, Taane G; Campino, Susana; Marinho, Claudio RF

"Pathotyping" Multiplex PCR Assay for Haemophilus parasuis: a Tool for Prediction of Virulence. (2017) Howell, Kate J; Weinert, Lucy A; Peters, Sarah E; Wang, Jinhong; Hernandez-Garcia, Juan; Chaudhuri, Roy R; Luan, Shi-Lu; Angen, Øystein; Aragon, Virginia; Williamson, Susanna M; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W

Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014. (2017) Hernandez-Garcia, Juan; Wang, Jinhong; Restif, Olivier; Holmes, Mark A; Mather, Alison E; Weinert, Lucy A; Wileman, Thomas M; Thomson, Jill R; Langford, Paul R; Wren, Brendan W; Rycroft, Andrew; Maskell, Duncan J; Tucker, Alexander W; BRADP1T Consortium

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Current and cumulative malaria infections in a setting embarking on elimination: Amhara, Ethiopia. (2017) Yalew, Woyneshet G; Pal, Sampa; Bansil, Pooja; Dabbs, Rebecca; Tetteh, Kevin; Guinovart, Caterina; Kalnoky, Michael; Serda, Belendia A; Tesfay, Berhane H; Beyene, Belay B; Seneviratne, Catherine; Littrell, Megan; Yokobe, Lindsay; Noland, Gregory S; Domingo, Gonzalo J; Getachew, Asefaw; Drakeley, Chris; Steketee, Richard W

Magnetic Resonance Imaging of Cerebral Malaria Patients Reveals Distinct Pathogenetic Processes in Different Parts of the Brain. (2017) Mohanty, Sanjib; Benjamin, Laura A; Majhi, Megharay; Panda, Premanand; Kampondeni, Sam; Sahu, Praveen K; Mohanty, Akshaya; Mahanta, Kishore C; Pattnaik, Rajyabardhan; Mohanty, Rashmi R; Joshi, Sonia; Mohanty, Anita; Turnbull, Ian W; Dondorp, Arjen M; Taylor, Terrie E; Wassmer, Samuel C

Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion. (2017) Hadfield, James; Harris, Simon R; Seth-Smith, Helena MB; Parmar, Surendra; Andersson, Patiyan; Giffard, Philip M; Schachter, Julius; Moncada, Jeanne; Ellison, Louise; Vaulet, María Lucía Gallo; Fermepin, Marcelo Rodríguez; Radebe, Frans; Mendoza, Suyapa; Ouburg, Sander; Morré, Servaas A; Sachse, Konrad; Puolakkainen, Mirja; Korhonen, Suvi J; Sonnex, Chris; Wiggins, Rebecca; Jalal, Hamid; Brunelli, Tamara; Casprini, Patrizia; Pitt, Rachel; Ison, Cathy; Savicheva, Alevtina; Shipitsyna, Elena; Hadad, Ronza; Kari, Laszlo; Burton, Matthew J; Mabey, David; Solomon, Anthony W; Lewis, David; Marsh, Peter; Unemo, Magnus; Clarke, Ian N; Parkhill, Julian; Thomson, Nicholas R

Whole Blood Profiling of Bacillus Calmette-Guérin-Induced Trained Innate Immunity in Infants Identifies Epidermal Growth Factor, IL-6, Platelet-Derived Growth Factor-AB/BB, and Natural Killer Cell Activation. (2017) Smith, Steven G; Kleinnijenhuis, Johanneke; Netea, Mihai G; Dockrell, Hazel M

Working together toward vaccines and biomarkers in the real world. (2017) Dockrell, Hazel M

The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys. (2017) Darton, Thomas C; Meiring, James E; Tonks, Susan; Khan, Md Arifuzzaman; Khanam, Farhana; Shakya, Mila; Thindwa, Deus; Baker, Stephen; Basnyat, Buddha; Clemens, John D; Dougan, Gordon; Dolecek, Christiane; Dunstan, Sarah J; Gordon, Melita A; Heyderman, Robert S; Holt, Kathryn E; Pitzer, Virginia E; Qadri, Firdausi; Zaman, K; Pollard, Andrew J; STRATAA Study Consortium

Minimal genetic change in Vibrio cholerae in Mozambique over time: Multilocus variable number tandem repeat analysis and whole genome sequencing. (2017) Garrine, Marcelino; Mandomando, Inácio; Vubil, Delfino; Nhampossa, Tacilta; Acacio, Sozinho; Li, Shan; Paulson, Joseph N; Almeida, Mathieu; Domman, Daryl; Thomson, Nicholas R; Alonso, Pedro; Stine, Oscar Colin

Septins restrict inflammation and protect zebrafish larvae from Shigella infection. (2017) Mazon-Moya, Maria J; Willis, Alexandra R; Torraca, Vincenzo; Boucontet, Laurent; Shenoy, Avinash R; Colucci-Guyon, Emma; Mostowy, Serge

Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion. (2017) McCarthy, Ronan R; Mazon-Moya, Maria J; Moscoso, Joana A; Hao, Youai; Lam, Joseph S; Bordi, Christophe; Mostowy, Serge; Filloux, Alain

Brucella neotomae Infection in Humans, Costa Rica. (2017) Suárez-Esquivel, Marcela; Ruiz-Villalobos, Nazareth; Jiménez-Rojas, César; Barquero-Calvo, Elías; Chacón-Díaz, Carlos; Víquez-Ruiz, Eunice; Rojas-Campos, Norman; Baker, Kate S; Oviedo-Sánchez, Gerardo; Amuy, Ernesto; Chaves-Olarte, Esteban; Thomson, Nicholas R; Moreno, Edgardo; Guzmán-Verri, Caterina

Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads. (2017) Wick, Ryan R; Judd, Louise M; Gorrie, Claire L; Holt, Kathryn E

Malaria Host Candidate Genes Validated by Association With Current, Recent, and Historical Measures of Transmission Intensity. (2017) Sepúlveda, Nuno; Manjurano, Alphaxard; Campino, Susana G; Lemnge, Martha; Lusingu, John; Olomi, Raimos; Rockett, Kirk A; Hubbart, Christina; Jeffreys, Anna; Rowlands, Kate; Clark, Taane G; Riley, Eleanor M; Drakeley, Chris J; MalariaGEN Consortium

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance. (2017) O'Neill, Paul M; Amewu, Richard K; Charman, Susan A; Sabbani, Sunil; Gnädig, Nina F; Straimer, Judith; Fidock, David A; Shore, Emma R; Roberts, Natalie L; Wong, Michael H-L; Hong, W David; Pidathala, Chandrakala; Riley, Chris; Murphy, Ben; Aljayyoussi, Ghaith; Gamo, Francisco Javier; Sanz, Laura; Rodrigues, Janneth; Cortes, Carolina Gonzalez; Herreros, Esperanza; Angulo-Barturén, Iñigo; Jiménez-Díaz, María Belén; Bazaga, Santiago Ferrer; Martínez-Martínez, María Santos; Campo, Brice; Sharma, Raman; Ryan, Eileen; Shackleford, David M; Campbell, Simon; Smith, Dennis A; Wirjanata, Grennady; Noviyanti, Rintis; Price, Ric N; Marfurt, Jutta; Palmer, Michael J; Copple, Ian M; Mercer, Amy E; Ruecker, Andrea; Delves, Michael J; Sinden, Robert E; Siegl, Peter; Davies, Jill; Rochford, Rosemary; Kocken, Clemens HM; Zeeman, Anne-Marie; Nixon, Gemma L; Biagini, Giancarlo A; Ward, Stephen A

Evolutionary dynamics and genomic features of the Elizabethkingia anophelis 2015 to 2016 Wisconsin outbreak strain. (2017) Perrin, Amandine; Larsonneur, Elise; Nicholson, Ainsley C; Edwards, David J; Gundlach, Kristin M; Whitney, Anne M; Gulvik, Christopher A; Bell, Melissa E; Rendueles, Olaya; Cury, Jean; Hugon, Perrine; Clermont, Dominique; Enouf, Vincent; Loparev, Vladimir; Juieng, Phalasy; Monson, Timothy; Warshauer, David; Elbadawi, Lina I; Walters, Maroya Spalding; Crist, Matthew B; Noble-Wang, Judith; Borlaug, Gwen; Rocha, Eduardo PC; Criscuolo, Alexis; Touchon, Marie; Davis, Jeffrey P; Holt, Kathryn E; McQuiston, John R; Brisse, Sylvain

Host Resistance to Plasmodium-Induced Acute Immune Pathology Is Regulated by Interleukin-10 Receptor Signaling. (2017) Claser, Carla; De Souza, J Brian; Thorburn, Samuel G; Grau, Georges Emile; Riley, Eleanor M; Rénia, Laurent; Hafalla, Julius CR

Association between functional antibody against Group B Streptococcus and maternal and infant colonization in a Gambian cohort. (2017) Le Doare, Kirsty; Faal, Amadou; Jaiteh, Mustapha; Sarfo, Francess; Taylor, Stephen; Warburton, Fiona; Humphries, Holly; Birt, Jessica; Jarju, Sheikh; Darboe, Saffiatou; Clarke, Edward; Antonio, Martin; Foster-Nyarko, Ebenezer; Heath, Paul T; Gorringe, Andrew; Kampmann, Beate

Resistance to malaria through structural variation of red blood cell invasion receptors. (2017) Leffler, Ellen M; Band, Gavin; Busby, George BJ; Kivinen, Katja; Le, Quang Si; Clarke, Geraldine M; Bojang, Kalifa A; Conway, David J; Jallow, Muminatou; Sisay-Joof, Fatoumatta; Bougouma, Edith C; Mangano, Valentina D; Modiano, David; Sirima, Sodiomon B; Achidi, Eric; Apinjoh, Tobias O; Marsh, Kevin; Ndila, Carolyne M; Peshu, Norbert; Williams, Thomas N; Drakeley, Chris; Manjurano, Alphaxard; Reyburn, Hugh; Riley, Eleanor; Kachala, David; Molyneux, Malcolm; Nyirongo, Vysaul; Taylor, Terrie; Thornton, Nicole; Tilley, Louise; Grimsley, Shane; Drury, Eleanor; Stalker, Jim; Cornelius, Victoria; Hubbart, Christina; Jeffreys, Anna E; Rowlands, Kate; Rockett, Kirk A; Spencer, Chris CA; Kwiatkowski, Dominic P; Malaria Genomic Epidemiology Network

Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen. (2017) Miguel-Blanco, Celia; Molina, Irene; Bardera, Ana I; Díaz, Beatriz; de Las Heras, Laura; Lozano, Sonia; González, Carolina; Rodrigues, Janneth; Delves, Michael J; Ruecker, Andrea; Colmenarejo, Gonzalo; Viera, Sara; Martínez-Martínez, María S; Fernández, Esther; Baum, Jake; Sinden, Robert E; Herreros, Esperanza

Early morning urine collection to improve urinary lateral flow LAM assay sensitivity in hospitalised patients with HIV-TB co-infection. (2017) Gina, Phindile; Randall, Philippa J; Muchinga, Tapuwa E; Pooran, Anil; Meldau, Richard; Peter, Jonny G; Dheda, Keertan

Genomic variation in Plasmodium vivax malaria reveals regions under selective pressure. (2017) Diez Benavente, Ernest; Ward, Zoe; Chan, Wilson; Mohareb, Fady R; Sutherland, Colin J; Roper, Cally; Campino, Susana; Clark, Taane G

European Chlamydia abortus livestock isolate genomes reveal unusual stability and limited diversity, reflected in geographical signatures. (2017) Seth-Smith, HMB; Busó, Leonor Sánchez; Livingstone, M; Sait, M; Harris, SR; Aitchison, KD; Vretou, Evangelia; Siarkou, VI; Laroucau, K; Sachse, K; Longbottom, D; Thomson, NR

The comparative immunology of wild and laboratory mice, Mus musculus domesticus. (2017) Abolins, Stephen; King, Elizabeth C; Lazarou, Luke; Weldon, Laura; Hughes, Louise; Drescher, Paul; Raynes, John G; Hafalla, Julius CR; Viney, Mark E; Riley, Eleanor M

Annotation of plasmid genes. (2017) Thomas, Christopher M; Thomson, Nicholas R; Cerdeño-Tárraga, Ana M; Brown, Celeste J; Top, Eva M; Frost, Laura S

Serological measures to assess the efficacy of malaria control programme on Ambae Island, Vanuatu. (2017) Idris, Zulkarnain Md; Chan, Chim W; Mohammed, Mubasher; Kalkoa, Morris; Taleo, George; Junker, Klara; Arcà, Bruno; Drakeley, Chris; Kaneko, Akira

Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis. (2017) Yeung, Amy TY; Hale, Christine; Lee, Amy H; Gill, Erin E; Bushell, Wendy; Parry-Smith, David; Goulding, David; Pickard, Derek; Roumeliotis, Theodoros; Choudhary, Jyoti; Thomson, Nick; Skarnes, William C; Dougan, Gordon; Hancock, Robert EW

Chytrid fungus infection in zebrafish demonstrates that the pathogen can parasitize non-amphibian vertebrate hosts. (2017) Liew, Nicole; Mazon Moya, Maria J; Wierzbicki, Claudia J; Hollinshead, Michael; Dillon, Michael J; Thornton, Christopher R; Ellison, Amy; Cable, Jo; Fisher, Matthew C; Mostowy, Serge

Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study. (2017) Lynch, Caroline A; Pearce, Richard; Pota, Hirva; Egwang, Connie; Egwang, Thomas; Bhasin, Amit; Cox, Jonathan; Abeku, Tarekegn A; Roper, Cally

Diagnostic antigens for visceral leishmaniasis: clarification of nomenclatures. (2017) Bhattacharyya, Tapan; Marlais, Tegwen; Miles, Michael A

LCCL protein complex formation in Plasmodium is critically dependent on LAP1. (2017) Tremp, Annie Z; Sharma, Vikram; Carter, Victoria; Lasonder, Edwin; Dessens, Johannes T

Concern regarding the alleged spread of hypervirulent lymphogranuloma venereum Chlamydia trachomatis strain in Europe. (2017) Seth-Smith, Helena Mb; Galán, Juan C; Goldenberger, Daniel; Lewis, David A; Peuchant, Olivia; Bébéar, Cecile; de Barbeyrac, Bertille; Bénard, Angele; Carter, Ian; Kok, Jen; Bruisten, Sylvia M; Versteeg, Bart; Morré, Servaas A; Thomson, Nicholas R; Egli, Adrian; de Vries, Henry Jc

Impact of metric and sample size on determining malaria hotspot boundaries. (2017) Stresman, Gillian H; Giorgi, Emanuele; Baidjoe, Amrish; Knight, Phil; Odongo, Wycliffe; Owaga, Chrispin; Shagari, Shehu; Makori, Euniah; Stevenson, Jennifer; Drakeley, Chris; Cox, Jonathan; Bousema, Teun; Diggle, Peter J

Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery. (2017) Bald, Dirk; Villellas, Cristina; Lu, Ping; Koul, Anil

Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling. (2017) Patin, Emmanuel C; Geffken, Anna C; Willcocks, Sam; Leschczyk, Christoph; Haas, Albert; Nimmerjahn, Falk; Lang, Roland; Ward, Theresa H; Schaible, Ulrich E

Whole genome sequencing of Shigella sonnei through PulseNet Latin America and Caribbean: advancing global surveillance of foodborne illnesses. (2017) Baker, KS; Campos, J; Pichel, M; Della Gaspera, A; Duarte-Martínez, F; Campos-Chacón, E; Bolaños-Acuña, HM; Guzmán-Verri, C; Mather, AE; Diaz Velasco, S; Zamudio Rojas, ML; Forbester, JL; Connor, TR; Keddy, KH; Smith, AM; López de Delgado, EA; Angiolillo, G; Cuaical, N; Fernández, J; Aguayo, C; Morales Aguilar, M; Valenzuela, C; Morales Medrano, AJ; Sirok, A; Weiler Gustafson, N; Diaz Guevara, PL; Montaño, LA; Perez, E; Thomson, NR

Efficacy of a novel, protein-based pneumococcal vaccine against nasopharyngeal carriage of Streptococcus pneumoniae in infants: A phase 2, randomized, controlled, observer-blind study. (2017) Odutola, Aderonke; Ota, Martin OC; Antonio, Martin; Ogundare, Ezra O; Saidu, Yauba; Foster-Nyarko, Ebenezer; Owiafe, Patrick K; Ceesay, Fatima; Worwui, Archibald; Idoko, Olubukola T; Owolabi, Olumuyiwa; Bojang, Abdoulie; Jarju, Sheikh; Drammeh, Isatou; Kampmann, Beate; Greenwood, Brian M; Alderson, Mark; Traskine, Magali; Devos, Nathalie; Schoonbroodt, Sonia; Swinnen, Kristien; Verlant, Vincent; Dobbelaere, Kurt; Borys, Dorota

Defining the next generation of Plasmodium vivax diagnostic tests for control and elimination: Target product profiles. (2017) Ding, Xavier C; Ade, Maria Paz; Baird, J Kevin; Cheng, Qin; Cunningham, Jane; Dhorda, Mehul; Drakeley, Chris; Felger, Ingrid; Gamboa, Dionicia; Harbers, Matthias; Herrera, Socrates; Lucchi, Naomi; Mayor, Alfredo; Mueller, Ivo; Sattabongkot, Jetsumon; Ratsimbason, Arsène; Richards, Jack; Tanner, Marcel; González, Iveth J

Variants of AbGRI3 carrying the armA gene in extensively antibiotic-resistant Acinetobacter baumannii from Singapore. (2017) Blackwell, Grace A; Holt, Kathryn E; Bentley, Stephen D; Hsu, Li Yang; Hall, Ruth M

Three Divergent Subpopulations of the Malaria Parasite Plasmodium knowlesi. (2017) Divis, Paul CS; Lin, Lee C; Rovie-Ryan, Jeffrine J; Kadir, Khamisah A; Anderios, Fread; Hisam, Shamilah; Sharma, Reuben SK; Singh, Balbir; Conway, David J

VivaxGEN: An open access platform for comparative analysis of short tandem repeat genotyping data in Plasmodium vivax populations. (2017) Trimarsanto, Hidayat; Benavente, Ernest D; Noviyanti, Rintis; Utami, Retno Ayu Setya; Trianty, Leily; Pava, Zuleima; Getachew, Sisay; Kim, Jung-Yeon; Goo, Youn-Kyoung; Wangchuck, Sonam; Liu, Yaobao; Gao, Qi; Dowd, Simone; Cheng, Qin; Clark, Taane G; Price, Ric N; Auburn, Sarah

Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans. (2017) Scott, Timothy A; Quintaneiro, Leonor M; Norvaisas, Povilas; Lui, Prudence P; Wilson, Matthew P; Leung, Kit-Yi; Herrera-Dominguez, Lucia; Sudiwala, Sonia; Pessia, Alberto; Clayton, Peter T; Bryson, Kevin; Velagapudi, Vidya; Mills, Philippa B; Typas, Athanasios; Greene, Nicholas DE; Cabreiro, Filipe

A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements. (2017) Ramírez-Vargas, Gabriel; Quesada-Gómez, Carlos; Acuña-Amador, Luis; López-Ureña, Diana; Murillo, Tatiana; Del Mar Gamboa-Coronado, María; Chaves-Olarte, Esteban; Thomson, Nicholas; Rodríguez-Cavallini, Evelyn; Rodríguez, César

The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme. (2017) Torraca, Vincenzo; Tulotta, Claudia; Snaar-Jagalska, B Ewa; Meijer, Annemarie H

Burkholderia pseudomallei and Burkholderia mallei vaccines: Are we close to clinical trials? (2017) Titball, Richard W; Burtnick, Mary N; Bancroft, Gregory J; Brett, Paul

Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress. (2017) Hale, Victoria L; Watermeyer, Jean M; Hackett, Fiona; Vizcay-Barrena, Gema; van Ooij, Christiaan; Thomas, James A; Spink, Matthew C; Harkiolaki, Maria; Duke, Elizabeth; Fleck, Roland A; Blackman, Michael J; Saibil, Helen R

Age, Weight, and CYP2D6 Genotype Are Major Determinants of Primaquine Pharmacokinetics in African Children. (2017) Gonçalves, Bronner P; Pett, Helmi; Tiono, Alfred B; Murry, Daryl; Sirima, Sodiomon B; Niemi, Mikko; Bousema, Teun; Drakeley, Chris; Ter Heine, Rob

Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976-78. (2017) Jovel, Irina T; Björkman, Anders; Roper, Cally; Mårtensson, Andreas; Ursing, Johan

Genetic diversity of next generation antimalarial targets: A baseline for drug resistance surveillance programmes. (2017) Gomes, Ana Rita; Ravenhall, Matt; Benavente, Ernest Diez; Talman, Arthur; Sutherland, Colin; Roper, Cally; Clark, Taane G; Campino, Susana

A systematic review on malaria sero-epidemiology studies in the Brazilian Amazon: insights into immunological markers for exposure and protection. (2017) Folegatti, Pedro M; Siqueira, André M; Monteiro, Wuelton M; Lacerda, Marcus Vinícius G; Drakeley, Chris J; Braga, Érika M

Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae. (2017) Bossé, Janine T; Li, Yanwen; Rogers, Jon; Fernandez Crespo, Roberto; Li, Yinghui; Chaudhuri, Roy R; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R

Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting. (2017) Musicha, Patrick; Feasey, Nicholas A; Cain, Amy K; Kallonen, Teemu; Chaguza, Chrispin; Peno, Chikondi; Khonga, Margaret; Thompson, Sarah; Gray, Katherine J; Mather, Alison E; Heyderman, Robert S; Everett, Dean B; Thomson, Nicholas R; Msefula, Chisomo L

The shape of the iceberg: quantification of submicroscopic Plasmodium falciparum and Plasmodium vivax parasitaemia and gametocytaemia in five low endemic settings in Ethiopia. (2017) Tadesse, Fitsum G; van den Hoogen, Lotus; Lanke, Kjerstin; Schildkraut, Jodie; Tetteh, Kevin; Aseffa, Abraham; Mamo, Hassen; Sauerwein, Robert; Felger, Ingrid; Drakeley, Chris; Gadissa, Endalamaw; Bousema, Teun

The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays. (2017) Tanner, Rachel; O'Shea, Matthew K; White, Andrew D; Müller, Julius; Harrington-Kandt, Rachel; Matsumiya, Magali; Dennis, Mike J; Parizotto, Eneida A; Harris, Stephanie; Stylianou, Elena; Naranbhai, Vivek; Bettencourt, Paulo; Drakesmith, Hal; Sharpe, Sally; Fletcher, Helen A; McShane, Helen

The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake. (2017) Sherling, Emma S; Knuepfer, Ellen; Brzostowski, Joseph A; Miller, Louis H; Blackman, Michael J; van Ooij, Christiaan

Assessing the impact of differences in malaria transmission intensity on clinical and haematological indices in children with malaria. (2017) Mensah-Brown, Henrietta E; Abugri, James; Asante, Kwaku P; Dwomoh, Duah; Dosoo, David; Atuguba, Frank; Conway, David J; Awandare, Gordon A

Incidence of macrolide-lincosamide-streptogramin B resistance amongst beta-haemolytic streptococci in The Gambia. (2017) Foster-Nyarko, Ebenezer; Kwambana, Brenda; Ceesay, Fatima; Jawneh, Kaddijatou; Darboe, Saffiatou; Mulwa, Sarah N; Ceesay, Buntung; Secka, Ousman O; Adetifa, Ifedayo; Antonio, Martin

Complex Routes of Nosocomial Vancomycin-Resistant Enterococcus faecium Transmission Revealed by Genome Sequencing. (2017) Raven, Kathy E; Gouliouris, Theodore; Brodrick, Hayley; Coll, Francesc; Brown, Nicholas M; Reynolds, Rosy; Reuter, Sandra; Török, M Estée; Parkhill, Julian; Peacock, Sharon J

Interleukin 10 inhibits pro-inflammatory cytokine responses and killing of Burkholderia pseudomallei. (2017) Kessler, Bianca; Rinchai, Darawan; Kewcharoenwong, Chidchamai; Nithichanon, Arnone; Biggart, Rachael; Hawrylowicz, Catherine M; Bancroft, Gregory J; Lertmemongkolchai, Ganjana

The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis. (2017) Lacerda, Eliana M; Bowman, Erinna W; Cliff, Jacqueline M; Kingdon, Caroline C; King, Elizabeth C; Lee, Ji-Sook; Clark, Taane G; Dockrell, Hazel M; Riley, Eleanor M; Curran, Hayley; Nacul, Luis

Palmitoylation of Plasmodium alveolins promotes cytoskeletal function. (2017) Tremp, Annie Z; Al-Khattaf, Fatimah S; Dessens, Johannes T

Population genetic structure and adaptation of malaria parasites on the edge of endemic distribution. (2017) Duffy, Craig W; Ba, Hampate; Assefa, Samuel; Ahouidi, Ambroise D; Deh, Yacine B; Tandia, Abderahmane; Kirsebom, Freja CM; Kwiatkowski, Dominic P; Conway, David J

The propensity of the bacterial rodlin protein RdlB to form amyloid fibrils determines its function in Streptomyces coelicolor. (2017) Yang, Wen; Willemse, Joost; Sawyer, Elizabeth B; Lou, Fei; Gong, Weibin; Zhang, Hong; Gras, Sally L; Claessen, Dennis; Perrett, Sarah

Serial QuantiFERON testing and tuberculosis disease risk among young children: an observational cohort study. (2017) Andrews, Jason R; Nemes, Elisa; Tameris, Michele; Landry, Bernard S; Mahomed, Hassan; McClain, J Bruce; Fletcher, Helen A; Hanekom, Willem A; Wood, Robin; McShane, Helen; Scriba, Thomas J; Hatherill, Mark

The importance of the glycosylation of antimicrobial peptides: natural and synthetic approaches. (2017) Bednarska, Natalia G; Wren, Brendan W; Willcocks, Sam J

Contribution of Plasmodium knowlesi to Multispecies Human Malaria Infections in North Sumatera, Indonesia. (2017) Lubis, Inke ND; Wijaya, Hendri; Lubis, Munar; Lubis, Chairuddin P; Divis, Paul CS; Beshir, Khalid B; Sutherland, Colin J

Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda. (2017) Ssewanyana, Isaac; Arinaitwe, Emmanuel; Nankabirwa, Joaniter I; Yeka, Adoke; Sullivan, Richard; Kamya, Moses R; Rosenthal, Philip J; Dorsey, Grant; Mayanja-Kizza, Harriet; Drakeley, Chris; Greenhouse, Bryan; Tetteh, Kevin KA

Hosts and vectors of Trypanosoma cruzi discrete typing units in the Chagas disease endemic region of the Paraguayan Chaco. (2017) Acosta, Nidia; López, Elsa; Lewis, Michael D; Llewellyn, Martin S; Gómez, Ana; Román, Fabiola; Miles, Michael A; Yeo, Matthew

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis. (2017) Andreu, Nuria; Phelan, Jody; de Sessions, Paola F; Cliff, Jacqueline M; Clark, Taane G; Hibberd, Martin L

Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples. (2017) Cowell, Annie N; Loy, Dorothy E; Sundararaman, Sesh A; Valdivia, Hugo; Fisch, Kathleen; Lescano, Andres G; Baldeviano, G Christian; Durand, Salomon; Gerbasi, Vince; Sutherland, Colin J; Nolder, Debbie; Vinetz, Joseph M; Hahn, Beatrice H; Winzeler, Elizabeth A

Draft Genome Sequence of Campylobacter jejuni 11168H. (2017) Macdonald, Sarah E; Gundogdu, Ozan; Dorrell, Nick; Wren, Brendan W; Blake, Damer; Stabler, Richard

Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins. (2017) Mesquita, Francisco Sarmento; Brito, Cláudia; Mazon Moya, Maria J; Pinheiro, Jorge Campos; Mostowy, Serge; Cabanes, Didier; Sousa, Sandra description

Human Immunology of Tuberculosis. (2017) Scriba, Thomas J; Coussens, Anna K; Fletcher, Helen A

Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays. (2017) Ajileye, Adebisi; Alvarez, Nataly; Merker, Matthias; Walker, Timothy M; Akter, Suriya; Brown, Kerstin; Moradigaravand, Danesh; Schön, Thomas; Andres, Sönke; Schleusener, Viola; Omar, Shaheed V; Coll, Francesc; Huang, Hairong; Diel, Roland; Ismail, Nazir; Parkhill, Julian; de Jong, Bouke C; Peto, Tim EA; Crook, Derrick W; Niemann, Stefan; Robledo, Jaime; Smith, E Grace; Peacock, Sharon J; Köser, Claudio U

An outbreak of norovirus GI-6 infection following a wedding in North West England. (2017) Smith, KC; Inns, T; Decraene, V; Fox, A; Allen, DJ; Shah, A

pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom. (2017) Sutherland, Colin J; Lansdell, Paul; Sanders, Mandy; Muwanguzi, Julian; van Schalkwyk, Donelly A; Kaur, Harparkash; Nolder, Debbie; Tucker, Julie; Bennett, Hayley M; Otto, Thomas D; Berriman, Matthew; Patel, Trupti A; Lynn, Roderick; Gkrania-Klotsas, Effrossyni; Chiodini, Peter L

Serology reveals heterogeneity of Plasmodium falciparum transmission in northeastern South Africa: implications for malaria elimination. (2017) Biggs, Joseph; Raman, Jaishree; Cook, Jackie; Hlongwana, Khumbulani; Drakeley, Chris; Morris, Natashia; Serocharan, Ishen; Agubuzo, Eunice; Kruger, Philip; Mabuza, Aaron; Zitha, Alpheus; Machaba, Elliot; Coetzee, Maureen; Kleinschmidt, Immo

Identification and initial characterisation of a protein involved in Campylobacter jejuni cell shape. (2017) Esson, Diane; Gupta, Srishti; Bailey, David; Wigley, Paul; Wedley, Amy; Mather, Alison E; Méric, Guillaume; Mastroeni, Pietro; Sheppard, Samuel K; Thomson, Nicholas R; Parkhill, Julian; Maskell, Duncan J; Christie, Graham; Grant, Andrew J

Culture adaptation of malaria parasites selects for convergent loss-of-function mutants. (2017) Claessens, Antoine; Affara, Muna; Assefa, Samuel A; Kwiatkowski, Dominic P; Conway, David J

Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods. (2017) Rhodes, Sophie J; Sarfas, Charlotte; Knight, Gwenan M; White, Andrew; Pathan, Ansar A; McShane, Helen; Evans, Thomas G; Fletcher, Helen; Sharpe, Sally; White, Richard G

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia. (2017) Clarke, Geraldine M; Rockett, Kirk; Kivinen, Katja; Hubbart, Christina; Jeffreys, Anna E; Rowlands, Kate; Jallow, Muminatou; Conway, David J; Bojang, Kalifa A; Pinder, Margaret; Usen, Stanley; Sisay-Joof, Fatoumatta; Sirugo, Giorgio; Toure, Ousmane; Thera, Mahamadou A; Konate, Salimata; Sissoko, Sibiry; Niangaly, Amadou; Poudiougou, Belco; Mangano, Valentina D; Bougouma, Edith C; Sirima, Sodiomon B; Modiano, David; Amenga-Etego, Lucas N; Ghansah, Anita; Koram, Kwadwo A; Wilson, Michael D; Enimil, Anthony; Evans, Jennifer; Amodu, Olukemi K; Olaniyan, Subulade; Apinjoh, Tobias; Mugri, Regina; Ndi, Andre; Ndila, Carolyne M; Uyoga, Sophie; Macharia, Alexander; Peshu, Norbert; Williams, Thomas N; Manjurano, Alphaxard; Sepúlveda, Nuno; Clark, Taane G; Riley, Eleanor; Drakeley, Chris; Reyburn, Hugh; Nyirongo, Vysaul; Kachala, David; Molyneux, Malcolm; Dunstan, Sarah J; Phu, Nguyen Hoan; Quyen, Nguyen Ngoc; Thai, Cao Quang; Hien, Tran Tinh; Manning, Laurens; Laman, Moses; Siba, Peter; Karunajeewa, Harin; Allen, Steve; Allen, Angela; Davis, Timothy Me; Michon, Pascal; Mueller, Ivo; Molloy, Síle F; Campino, Susana; Kerasidou, Angeliki; Cornelius, Victoria J; Hart, Lee; Shah, Shivang S; Band, Gavin; Spencer, Chris Ca; Agbenyega, Tsiri; Achidi, Eric; Doumbo, Ogobara K; Farrar, Jeremy; Marsh, Kevin; Taylor, Terrie; Kwiatkowski, Dominic P; MalariaGEN Consortium

Effectiveness of a serological tool to predict malaria transmission intensity in an elimination setting. (2017) Dewasurendra, Rajika Lasanthi; Dias, Janaka Nandana; Sepulveda, Nuno; Gunawardena, Geethika Sharmini Abayaweera; Chandrasekharan, Naduviladath; Drakeley, Chris; Karunaweera, Nadira Dharshani

Boosting of post-exposure human T-cell and B-cell recall responses in vivo by Burkholderia pseudomallei-related proteins. (2017) Nithichanon, Arnone; Gourlay, Louise J; Bancroft, Gregory J; Ato, Manabu; Takahashi, Yoshimasa; Lertmemongkolchai, Ganjana

Whole Genome Sequence Analysis of Salmonella Typhi Isolated in Thailand before and after the Introduction of a National Immunization Program. (2017) Dyson, Zoe A; Thanh, Duy Pham; Bodhidatta, Ladaporn; Mason, Carl Jeffries; Srijan, Apichai; Rabaa, Maia A; Vinh, Phat Voong; Thanh, Tuyen Ha; Thwaites, Guy E; Baker, Stephen; Holt, Kathryn E

Malaria epidemiology in central Myanmar: identification of a multi-species asymptomatic reservoir of infection. (2017) Ghinai, Isaac; Cook, Jackie; Hla, Teddy Tun Win; Htet, Hein Myat Thu; Hall, Tom; Lubis, Inke Nd; Ghinai, Rosanna; Hesketh, Therese; Naung, Ye; Lwin, Mya Mya; Latt, Tint Swe; Heymann, David L; Sutherland, Colin J; Drakeley, Chris; Field, Nigel

Correction: Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole. (2017) Fougère, Aurélie; Jackson, Andrew P; Bechtsi, Dafni Paraskevi; Braks, Joanna AM; Annoura, Takeshi; Fonager, Jannik; Spaccapelo, Roberta; Ramesar, Jai; Chevalley-Maurel, Séverine; Klop, Onny; van der Laan, Annelies MA; Tanke, Hans J; Kocken, Clemens HM; Pasini, Erica M; Khan, Shahid M; Böhme, Ulrike; van Ooij, Christiaan; Otto, Thomas D; Janse, Chris J; Franke-Fayard, Blandine

Spatial Distribution of Falciparum Malaria Infections in Zanzibar: Implications for Focal Drug Administration Strategies Targeting Asymptomatic Parasite Carriers. (2017) Björkman, Anders; Cook, Jackie; Sturrock, Hugh; Msellem, Mwinyi; Ali, Abdullah; Xu, Weiping; Molteni, Fabrizio; Gosling, Roly; Drakeley, Chris; Mårtensson, Andreas

Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis. (2017) Dowdy, David W; Grant, Alison D; Dheda, Keertan; Nardell, Edward; Fielding, Katherine; Moore, David AJ

Individual-level factors associated with the risk of acquiring human Plasmodium knowlesi malaria in Malaysia: a case-control study. (2017) Grigg, Matthew J; Cox, Jonathan; William, Timothy; Jelip, Jenarun; Fornace, Kimberly M; Brock, Patrick M; von Seidlein, Lorenz; Barber, Bridget E; Anstey, Nicholas M; Yeo, Tsin W; Drakeley, Christopher J

A Molecular Assay to Quantify Male and Female Plasmodium falciparum Gametocytes: Results From 2 Randomized Controlled Trials Using Primaquine for Gametocyte Clearance. (2017) Stone, Will; Sawa, Patrick; Lanke, Kjerstin; Rijpma, Sanna; Oriango, Robin; Nyaurah, Maureen; Osodo, Paul; Osoti, Victor; Mahamar, Almahamoudou; Diawara, Halimatou; Woestenenk, Rob; Graumans, Wouter; van de Vegte-Bolmer, Marga; Bradley, John; Chen, Ingrid; Brown, Joelle; Siciliano, Giulia; Alano, Pietro; Gosling, Roly; Dicko, Alassane; Drakeley, Chris; Bousema, Teun

Molecular Markers for Sensitive Detection of Plasmodium falciparum Asexual Stage Parasites and their Application in a Malaria Clinical Trial. (2017) Tadesse, Fitsum G; Lanke, Kjerstin; Nebie, Issa; Schildkraut, Jodie A; Gonçalves, Bronner P; Tiono, Alfred B; Sauerwein, Robert; Drakeley, Chris; Bousema, Teun; Rijpma, Sanna R

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Antileishmanial and antitrypanosomal drug identification. (2017) Croft, Simon L; Chatelain, Eric; Barrett, Michael P picture_as_pdf

The complex relationship between the emerging flaviviruses: dengue and Zika. (2017) Tan, Min Jie Alvin; Gaunt, Michael W; Hibberd, Martin L; Furnham, Nicholas picture_as_pdf

The inflammatory chemokine Cxcl18b exerts neutrophil-specific chemotaxis via the promiscuous chemokine receptor Cxcr2 in zebrafish. (2017) Torraca, Vincenzo; Otto, Natasja A; Tavakoli-Tameh, Aidin; Meijer, Annemarie H picture_as_pdf