LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Immunology and Infection (-2019) (972)

Dept of Pathogen Molecular Biology (-2019) (1192) Month Authors/Creators Item Type Full Text

December 2015

Estimating malaria parasite prevalence from community surveys in Uganda: a comparison of microscopy, rapid diagnostic tests and polymerase chain reaction. (2015) Nankabirwa, Joaniter I; Yeka, Adoke; Arinaitwe, Emmanuel; Kigozi, Ruth; Drakeley, Chris; Kamya, Moses R; Greenhouse, Bryan; Rosenthal, Philip J; Dorsey, Grant; Staedke, Sarah G

Sample size and power calculations for detecting changes in malaria transmission using antibody seroconversion rate. (2015) Sepúlveda, Nuno; Paulino, Carlos Daniel; Drakeley, Chris

Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development. (2015) Green, Judith L; Moon, Robert W; Whalley, David; Bowyer, Paul W; Wallace, Claire; Rochani, Ankit; Nageshan, Rishi K; Howell, Steven A; Grainger, Munira; Jones, Hayley M; Ansell, Keith H; Chapman, Timothy M; Taylor, Debra L; Osborne, Simon A; Baker, David A; Tatu, Utpal; Holder, Anthony A

Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei. (2015) Moule, Madeleine G; Spink, Natasha; Willcocks, Sam; Lim, Jiali; Guerra-Assunção, José Afonso; Cia, Felipe; Champion, Olivia L; Senior, Nicola J; Atkins, Helen S; Clark, Taane; Bancroft, Gregory J; Cuccui, Jon; Wren, Brendan W

Introduction and establishment of fluoroquinolone-resistant Shigella sonnei into Bhutan. (2015) Chung The, Hao; Rabaa, Maia A; Thanh, Duy Pham; Ruekit, Sirigade; Wangchuk, Sonam; Dorji, Tshering; Tshering, Kinzang Pem; Nguyen, To Nguyen Thi; Vinh, Phat Voong; Thanh, Tuyen Ha; Minh, Chau Nguyen Ngoc; Turner, Paul; Sar, Poda; Thwaites, Guy; Holt, Kathryn E; Thomson, Nicholas R; Bodhidatta, Ladaporn; Jeffries Mason, Carl; Baker, Stephen

Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN). (2015) WAMIN consortium authors include (in alphabetical order):; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Awandare, Gordon A; Bei, Amy K; Conway, David J; Diakite, Mahamadou; Duraisingh, Manoj T; Rayner, Julian C; Zenonos, Zenon A

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes. (2015) Vos, Martijn W; Stone, Will JR; Koolen, Karin M; van Gemert, Geert-Jan; van Schaijk, Ben; Leroy, Didier; Sauerwein, Robert W; Bousema, Teun; Dechering, Koen J

Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence. (2015) Kumar, Nitin; Miyajima, Fabio; He, Miao; Roberts, Paul; Swale, Andrew; Ellison, Louise; Pickard, Derek; Smith, Godfrey; Molyneux, Rebecca; Dougan, Gordon; Parkhill, Julian; Wren, Brendan W; Parry, Christopher M; Pirmohamed, Munir; Lawley, Trevor D

Genome Sequence of Acinetobacter baumannii Strain D36, an Antibiotic-Resistant Isolate from Lineage 2 of Global Clone 1. (2015) Hamidian, Mohammad; Hawkey, Jane; Holt, Kathryn E; Hall, Ruth M

Disruption of Specific RNA-RNA Interactions in a Double-Stranded RNA Virus Inhibits Genome Packaging and Virus Infectivity. (2015) Fajardo, Teodoro; Sung, Po-Yu; Roy, Polly

Atomic model of a nonenveloped virus reveals pH sensors for a coordinated process of cell entry. (2015) Zhang, Xing; Patel, Avnish; Celma, Cristina C; Yu, Xuekui; Roy, Polly; Zhou, Z Hong

Current Mathematical Models for Analyzing Anti-Malarial Antibody Data with an Eye to Malaria Elimination and Eradication. (2015) Sepúlveda, Nuno; Stresman, Gillian; White, Michael T; Drakeley, Chris J

A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes. (2015) Watermeyer, Jean M; Hale, Victoria L; Hackett, Fiona; Clare, Daniel K; Cutts, Erin E; Vakonakis, Ioannis; Fleck, Roland A; Blackman, Michael J; Saibil, Helen R

Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease. (2015) Sawyer, Elizabeth B; Edgeworth, Julie Ann; Thomas, Claire; Collinge, John; Jackson, Graham S

70th Anniversary Collection for the Microbiology Society: Microbial Genomics. (2015) Bentley, Stephen; Thomson, Nicholas

November 2015

Design, synthesis and antitrypanosomal activities of 2,6-disubstituted-4,5,7-trifluorobenzothiophenes. (2015) Bhambra, Avninder S; Edgar, Mark; Elsegood, Mark RJ; Li, Yuqi; Weaver, George W; Arroo, Randolph RJ; Yardley, Vanessa; Burrell-Saward, Hollie; Krystof, Vladimir

Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence. (2015) Butt, Aaron; Halliday, Nigel; Williams, Paul; Atkins, Helen S; Bancroft, Gregory J; Titball, Richard W

Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study. (2015) Roberts, Chrissy H; Franklin, Christopher S; Makalo, Pateh; Joof, Hassan; Sarr, Isatou; Mahdi, Olaimatu S; Sillah, Ansumana; Bah, Momodou; Payne, Felicity; Jeffreys, Anna E; Bottomley, William; Natividad, Angels; Molina-Gonzalez, Sandra; Burr, Sarah E; Preston, Mark; Kwiatkowski, Dominic; Rockett, Kirk A; Clark, Taane G; Burton, Matthew J; Mabey, David CW; Bailey, Robin; Barroso, Inês; Holland, Martin J

Cost and cost-effectiveness of newborn home visits: findings from the Newhints cluster-randomised controlled trial in rural Ghana. (2015) Pitt, Catherine; Tawiah, Theresa; Soremekun, Seyi; ten Asbroek, Augustinus HA; Manu, Alexander; Tawiah-Agyemang, Charlotte; Hill, Zelee; Owusu-Agyei, Seth; Kirkwood, Betty R; Hanson, Kara

Population Structure Shapes Copy Number Variation in Malaria Parasites. (2015) Cheeseman, Ian H; Miller, Becky; Tan, John C; Tan, Asako; Nair, Shalini; Nkhoma, Standwell C; De Donato, Marcos; Rodulfo, Hectorina; Dondorp, Arjen; Branch, Oralee H; Mesia, Lastenia Ruiz; Newton, Paul; Mayxay, Mayfong; Amambua-Ngwa, Alfred; Conway, David J; Nosten, François; Ferdig, Michael T; Anderson, Tim JC

Functional analysis of N-linking oligosaccharyl transferase enzymes encoded by deep-sea vent proteobacteria. (2015) Mills, Dominic C; Jervis, Adrian J; Abouelhadid, Sherif; Yates, Laura E; Cuccui, Jon; Linton, Dennis; Wren, Brendan W description

Clinical and epidemiological features of leishmaniasis in northwestern-Argentina through a retrospective analysis of recent cases. (2015) García Bustos, María F; González-Prieto, Gabriela; Ramos, Federico; Mora, María C; Hashiguchi, Yoshihisa; Parodi, Cecilia; Basombrío, Miguel A; Moreno, Sonia; Monroig, Sibila; Beckar, Josefina; Jaime, Daniela; Sajama, Jesús; Yeo, Matthew; Marco, Jorge D; Locatelli, Fabricio M; Barrio, Alejandra

Glycophorins, Blood Groups, and Protection from Severe Malaria. (2015) Wassmer, Samuel C; Carlton, Jane M

Plasmodium vivax Transmission in Africa. (2015) Howes, Rosalind E; Reiner, Robert C; Battle, Katherine E; Longbottom, Joshua; Mappin, Bonnie; Ordanovich, Dariya; Tatem, Andrew J; Drakeley, Chris; Gething, Peter W; Zimmerman, Peter A; Smith, David L; Hay, Simon I

FunTree: advances in a resource for exploring and contextualising protein function evolution. (2015) Sillitoe, Ian; Furnham, Nicholas

Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies. (2015) Furnham, Nicholas; Dawson, Natalie L; Rahman, Syed A; Thornton, Janet M; Orengo, Christine A

A comparison of Plasmodium falciparum circumsporozoite protein-based slot blot and ELISA immuno-assays for oocyst detection in mosquito homogenates. (2015) Stone, Will; Grabias, Bryan; Lanke, Kjerstin; Zheng, Hong; Locke, Emily; Diallo, Diadier; Birkett, Ashley; Morin, Merribeth; Bousema, Teun; Kumar, Sanjai

Isolation and Potential for Transmission of Mycobacterium bovis at Human-livestock-wildlife Interface of the Serengeti Ecosystem, Northern Tanzania. (2015) Katale, BZ; Mbugi, EV; Siame, KK; Keyyu, JD; Kendall, S; Kazwala, RR; Dockrell, HM; Fyumagwa, RD; Michel, AL; Rweyemamu, M; Streicher, EM; Warren, RM; van Helden, P; Matee, MI ['material/summary:fileicon_application/msword' not defined]

Vibrio cholerae Serogroup O139: Isolation from Cholera Patients and Asymptomatic Household Family Members in Bangladesh between 2013 and 2014. (2015) Chowdhury, Fahima; Mather, Alison E; Begum, Yasmin Ara; Asaduzzaman, Muhammad; Baby, Nabilah; Sharmin, Salma; Biswas, Rajib; Uddin, Muhammad Ikhtear; LaRocque, Regina C; Harris, Jason B; Calderwood, Stephen B; Ryan, Edward T; Clemens, John D; Thomson, Nicholas R; Qadri, Firdausi

Individual-level factors associated with variation in mycobacterial-specific immune response: Gender and previous BCG vaccination status. (2015) Rhodes, Sophie J; Knight, Gwenan M; Fielding, Katherine; Scriba, Thomas J; Pathan, Ansar A; McShane, Helen; Fletcher, Helen; White, Richard G description

Campylobacter jejuni outer membrane vesicle-associated proteolytic activity promotes bacterial invasion by mediating cleavage of intestinal epithelial cell E-cadherin and occludin. (2015) Elmi, Abdi; Nasher, Fauzy; Jagatia, Heena; Gundogdu, Ozan; Bajaj-Elliott, Mona; Wren, Brendan; Dorrell, Nick

Chronic Infection With Camelid Hepatitis E Virus in a Liver Transplant Recipient Who Regularly Consumes Camel Meat and Milk. (2015) Lee, Guan-Huei; Tan, Boon-Huan; Teo, Esmeralda Chi-Yuan; Lim, Seng-Gee; Dan, Yock-Young; Wee, Aileen; Aw, Pauline Poh Kim; Zhu, Yuan; Hibberd, Martin Lloyd; Tan, Chee-Kiat; Purdy, Michael A; Teo, Chong-Gee

Comparison of microarray-predicted closest genomes to sequencing for poliovirus vaccine strain similarity and influenza A phylogeny. (2015) Maurer-Stroh, Sebastian; Lee, Charlie WH; Patel, Champa; Lucero, Marilla; Nohynek, Hanna; Sung, Wing-Kin; Murad, Chrysanti; Ma, Jianmin; Hibberd, Martin L; Wong, Christopher W; Simões, Eric AF

Multiple Origins of Mutations in the mdr1 Gene--A Putative Marker of Chloroquine Resistance in P. vivax. (2015) Schousboe, Mette L; Ranjitkar, Samir; Rajakaruna, Rupika S; Amerasinghe, Priyanie H; Morales, Francisco; Pearce, Richard; Ord, Rosalyn; Leslie, Toby; Rowland, Mark; Gadalla, Nahla B; Konradsen, Flemming; Bygbjerg, Ib C; Roper, Cally; Alifrangis, Michael

Whole genome investigation of a divergent clade of the pathogen Streptococcus suis. (2015) Baig, Abiyad; Weinert, Lucy A; Peters, Sarah E; Howell, Kate J; Chaudhuri, Roy R; Wang, Jinhong; Holden, Matthew TG; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J

October 2015

Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity. (2015) Tyagi, Nidhi; Farnell, Edward J; Fitzsimmons, Colin M; Ryan, Stephanie; Tukahebwa, Edridah; Maizels, Rick M; Dunne, David W; Thornton, Janet M; Furnham, Nicholas

Use of different transmission metrics to describe malaria epidemiology in the highlands of western Kenya. (2015) Stevenson, Jennifer C; Stresman, Gillian H; Baidjoe, Amrish; Okoth, Albert; Oriango, Robin; Owaga, Chrispin; Marube, Elizabeth; Bousema, Teun; Cox, Jonathan; Drakeley, Chris

Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs. (2015) van Schalkwyk, Donelly A; Nash, Megan N; Shafik, Sarah H; Summers, Robert L; Lehane, Adele M; Smith, Peter J; Martin, Rowena E

Chromosomal integration vectors allowing flexible expression of foreign genes in Campylobacter jejuni. (2015) Jervis, Adrian J; Butler, Jonathan A; Wren, Brendan W; Linton, Dennis

T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients. (2015) Jenjaroen, Kemajittra; Chumseng, Suchintana; Sumonwiriya, Manutsanun; Ariyaprasert, Pitchayanant; Chantratita, Narisara; Sunyakumthorn, Piyanate; Hongsuwan, Maliwan; Wuthiekanun, Vanaporn; Fletcher, Helen A; Teparrukkul, Prapit; Limmathurotsakul, Direk; Day, Nicholas PJ; Dunachie, Susanna J

Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study. (2015) Biraro, Irene Andia; Egesa, Moses; Kimuda, Simon; Smith, Steven G; Toulza, Frederic; Levin, Jonathan; Joloba, Moses; Katamba, Achilles; Cose, Stephen; Dockrell, Hazel M; Elliott, Alison M

Draft Genome Sequence of the Enteropathogenic Bacterium Campylobacter jejuni Strain cj255. (2015) Siddiqui, Fariha Masood; Ibrahim, Muhammad; Noureen, Nighat; Noreen, Zobia; Titball, Richard W; Champion, Olivia L; Wren, Brendan W; Studholme, David; Bokhari, Habib

Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes. (2015) Zoltner, Martin; Leung, Ka Fai; Alsford, Sam; Horn, David; Field, Mark C

Serology describes a profile of declining malaria transmission in Farafenni, The Gambia. (2015) van den Hoogen, Lotus L; Griffin, Jamie T; Cook, Jackie; Sepúlveda, Nuno; Corran, Patrick; Conway, David J; Milligan, Paul; Affara, Muna; Allen, Stephen J; Proietti, Carla; Ceesay, Serign J; Targett, Geoffrey A; D'Alessandro, Umberto; Greenwood, Brian; Riley, Eleanor M; Drakeley, Chris

Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations. (2015) Abdallah, Abdallah M; Hill-Cawthorne, Grant A; Otto, Thomas D; Coll, Francesc; Guerra-Assunção, José Afonso; Gao, Ge; Naeem, Raeece; Ansari, Hifzur; Malas, Tareq B; Adroub, Sabir A; Verboom, Theo; Ummels, Roy; Zhang, Huoming; Panigrahi, Aswini Kumar; McNerney, Ruth; Brosch, Roland; Clark, Taane G; Behr, Marcel A; Bitter, Wilbert; Pain, Arnab

Delayed Onset of Symptoms and Atovaquone-Proguanil Chemoprophylaxis Breakthrough by Plasmodium malariae in the Absence of Mutation at Codon 268 of pmcytb. (2015) Teo, Beatrix Huei-Yi; Lansdell, Paul; Smith, Valerie; Blaze, Marie; Nolder, Debbie; Beshir, Khalid B; Chiodini, Peter L; Cao, Jun; Färnert, Anna; Sutherland, Colin J

Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity. (2015) Di Pietro, Ornella; Vicente-García, Esther; Taylor, Martin C; Berenguer, Diana; Viayna, Elisabet; Lanzoni, Anna; Sola, Irene; Sayago, Helena; Riera, Cristina; Fisa, Roser; Clos, M Victòria; Pérez, Belén; Kelly, John M; Lavilla, Rodolfo; Muñoz-Torrero, Diego

Variation in Complexity of Infection and Transmission Stability between Neighbouring Populations of Plasmodium vivax in Southern Ethiopia. (2015) Getachew, Sisay; To, Sheren; Trimarsanto, Hidayat; Thriemer, Kamala; Clark, Taane G; Petros, Beyene; Aseffa, Abraham; Price, Ric N; Auburn, Sarah

Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs. (2015) Das, Sujaan; Hertrich, Nadine; Perrin, Abigail J; Withers-Martinez, Chrislaine; Collins, Christine R; Jones, Matthew L; Watermeyer, Jean M; Fobes, Elmar T; Martin, Stephen R; Saibil, Helen R; Wright, Gavin J; Treeck, Moritz; Epp, Christian; Blackman, Michael J

Seasonal and Spatial Dynamics of the Primary Vector of Plasmodium knowlesi within a Major Transmission Focus in Sabah, Malaysia. (2015) Wong, Meng L; Chua, Tock H; Leong, Cherng S; Khaw, Loke T; Fornace, Kimberly; Wan-Sulaiman, Wan-Yusoff; William, Timothy; Drakeley, Chris; Ferguson, Heather M; Vythilingam, Indra

Population genomic structure and adaptation in the zoonotic malaria parasite Plasmodium knowlesi. (2015) Assefa, Samuel; Lim, Caeul; Preston, Mark D; Duffy, Craig W; Nair, Mridul B; Adroub, Sabir A; Kadir, Khamisah A; Goldberg, Jonathan M; Neafsey, Daniel E; Divis, Paul; Clark, Taane G; Duraisingh, Manoj T; Conway, David J; Pain, Arnab; Singh, Balbir

Pancreatic amylase is an environmental signal for regulation of biofilm formation and host interaction in Campylobacter jejuni. (2015) Jowiya, Waheed; Brunner, Katja; Abouelhadid, Sherif; Hussain, Haitham A; Nair, Sean P; Sadiq, Sohaib; Williams, Lisa K; Trantham, Emma K; Stephenson, Holly; Wren, Brendan W; Bajaj-Elliott, Mona; Cogan, Tristan A; Laws, Andrew P; Wade, Jim; Dorrell, Nick; Allan, Elaine

Asymptomatic and Submicroscopic Carriage of Plasmodium knowlesi Malaria in Household and Community Members of Clinical Cases in Sabah, Malaysia. (2015) Fornace, Kimberly M; Nuin, Nor Afizah; Betson, Martha; Grigg, Matthew J; William, Timothy; Anstey, Nicholas M; Yeo, Tsin W; Cox, Jonathan; Ying, Lau Tiek; Drakeley, Chris J

The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease. (2015) Conejero, Laura; Potempa, Krzysztof; Graham, Christine M; Spink, Natasha; Blankley, Simon; Salguero, Francisco J; Pankla-Sranujit, Rungnapa; Khaenam, Prasong; Banchereau, Jacques F; Pascual, Virginia; Chaussabel, Damien; Lertmemongkolchai, Ganjana; O'Garra, Anne; Bancroft, Gregory J description

A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli. (2015) Njoroge, Samuel M; Boinett, Christine J; Madé, Laure F; Ouko, Tom T; Fèvre, Eric M; Thomson, Nicholas R; Kariuki, Samuel

Bandage: interactive visualization of de novo genome assemblies. (2015) Wick, Ryan R; Schultz, Mark B; Zobel, Justin; Holt, Kathryn E

September 2015

Influence of malaria transmission intensity and the 581G mutation on the efficacy of intermittent preventive treatment in pregnancy: systematic review and meta-analysis. (2015) Chico, R Matthew; Cano, Jorge; Ariti, Cono; Collier, Timothy J; Chandramohan, Daniel; Roper, Cally; Greenwood, Brian

Development of a Multiplex PCR Assay for Rapid Molecular Serotyping of Haemophilus parasuis. (2015) Howell, Kate J; Peters, Sarah E; Wang, Jinhong; Hernandez-Garcia, Juan; Weinert, Lucy A; Luan, Shi-Lu; Chaudhuri, Roy R; Angen, Øystein; Aragon, Virginia; Williamson, Susanna M; Parkhill, Julian; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Maskell, Duncan J; Tucker, Alexander W; BRaDP1T Consortium

Effectiveness of a Home-Based Counselling Strategy on Neonatal Care and Survival: A Cluster-Randomised Trial in Six Districts of Rural Southern Tanzania. (2015) Hanson, Claudia; Manzi, Fatuma; Mkumbo, Elibariki; Shirima, Kizito; Penfold, Suzanne; Hill, Zelee; Shamba, Donat; Jaribu, Jennie; Hamisi, Yuna; Soremekun, Seyi; Cousens, Simon; Marchant, Tanya; Mshinda, Hassan; Schellenberg, David; Tanner, Marcel; Schellenberg, Joanna

Directional gene flow and ecological separation in Yersinia enterocolitica. (2015) Reuter, Sandra; Corander, Jukka; de Been, Mark; Harris, Simon; Cheng, Lu; Hall, Miquette; Thomson, Nicholas R; McNally, Alan

The Murray collection of pre-antibiotic era Enterobacteriacae: a unique research resource. (2015) Baker, Kate S; Burnett, Edward; McGregor, Hannah; Deheer-Graham, Ana; Boinett, Christine; Langridge, Gemma C; Wailan, Alexander M; Cain, Amy K; Thomson, Nicholas R; Russell, Julie E; Parkhill, Julian

Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis. (2015) Chertow, Jessica H; Alkaitis, Matthew S; Nardone, Glenn; Ikeda, Allison K; Cunnington, Aubrey J; Okebe, Joseph; Ebonyi, Augustine O; Njie, Madi; Correa, Simon; Jayasooriya, Shamanthi; Casals-Pascual, Climent; Billker, Oliver; Conway, David J; Walther, Michael; Ackerman, Hans

Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes. (2015) Naranbhai, Vivek; Fletcher, Helen A; Tanner, Rachel; O'Shea, Matthew K; McShane, Helen; Fairfax, Benjamin P; Knight, Julian C; Hill, Adrian VS

Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection. (2015) Hochman, Sarah E; Madaline, Theresa F; Wassmer, Samuel C; Mbale, Emmie; Choi, Namjong; Seydel, Karl B; Whitten, Richard O; Varughese, Julie; Grau, Georges ER; Kamiza, Steve; Molyneux, Malcolm E; Taylor, Terrie E; Lee, Sunhee; Milner, Danny A; Kim, Kami

A systematic review of sub-microscopic Plasmodium vivax infection. (2015) Moreira, Clarissa M; Abo-Shehada, Mahmoud; Price, Ric N; Drakeley, Chris J

The distribution of Blastocystis subtypes in isolates from Qatar. (2015) Abu-Madi, Marawan; Aly, Mahmoud; Behnke, Jerzy M; Clark, C Graham; Balkhy, Hanan

Intracellular Cytokine Staining and Flow Cytometry: Considerations for Application in Clinical Trials of Novel Tuberculosis Vaccines. (2015) Smith, Steven G; Smits, Kaatje; Joosten, Simone A; van Meijgaarden, Krista E; Satti, Iman; Fletcher, Helen A; Caccamo, Nadia; Dieli, Francesco; Mascart, Francoise; McShane, Helen; Dockrell, Hazel M; Ottenhoff, Tom HM; TBVI TB Biomarker Working Group

PD-1, PD-L1 and PD-L2 Gene Expression on T-Cells and Natural Killer Cells Declines in Conjunction with a Reduction in PD-1 Protein during the Intensive Phase of Tuberculosis Treatment. (2015) Hassan, Syeda S; Akram, Muhammad; King, Elizabeth C; Dockrell, Hazel M; Cliff, Jacqueline M

Excessive Cytolytic Responses Predict Tuberculosis Relapse After Apparently Successful Treatment. (2015) Cliff, Jacqueline M; Cho, Jang-Eun; Lee, Ji-Sook; Ronacher, Katharina; King, Elizabeth C; van Helden, Paul; Walzl, Gerhard; Dockrell, Hazel M

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial. (2015) White, Michael T; Verity, Robert; Griffin, Jamie T; Asante, Kwaku Poku; Owusu-Agyei, Seth; Greenwood, Brian; Drakeley, Chris; Gesase, Samwel; Lusingu, John; Ansong, Daniel; Adjei, Samuel; Agbenyega, Tsiri; Ogutu, Bernhards; Otieno, Lucas; Otieno, Walter; Agnandji, Selidji T; Lell, Bertrand; Kremsner, Peter; Hoffman, Irving; Martinson, Francis; Kamthunzu, Portia; Tinto, Halidou; Valea, Innocent; Sorgho, Hermann; Oneko, Martina; Otieno, Kephas; Hamel, Mary J; Salim, Nahya; Mtoro, Ali; Abdulla, Salim; Aide, Pedro; Sacarlal, Jahit; Aponte, John J; Njuguna, Patricia; Marsh, Kevin; Bejon, Philip; Riley, Eleanor M; Ghani, Azra C

Population Genetics, Evolutionary Genomics, and Genome-Wide Studies of Malaria: A View Across the International Centers of Excellence for Malaria Research. (2015) Carlton, Jane M; Volkman, Sarah K; Uplekar, Swapna; Hupalo, Daniel N; Pereira Alves, João Marcelo; Cui, Liwang; Donnelly, Martin; Roos, David S; Harb, Omar S; Acosta, Monica; Read, Andrew; Ribolla, Paulo EM; Singh, Om P; Valecha, Neena; Wassmer, Samuel C; Ferreira, Marcelo; Escalante, Ananias A

August 2015

A simple, high-throughput, colourimetric, field applicable loop-mediated isothermal amplification (HtLAMP) assay for malaria elimination. (2015) Britton, Sumudu; Cheng, Qin; Sutherland, Colin J; McCarthy, James S

Genetic determinants of anti-malarial acquired immunity in a large multi-centre study. (2015) Shelton, Jennifer MG; Corran, Patrick; Risley, Paul; Silva, Nilupa; Hubbart, Christina; Jeffreys, Anna; Rowlands, Kate; Craik, Rachel; Cornelius, Victoria; Hensmann, Meike; Molloy, Sile; Sepulveda, Nuno; Clark, Taane G; Band, Gavin; Clarke, Geraldine M; Spencer, Christopher CA; Kerasidou, Angeliki; Campino, Susana; Auburn, Sarah; Tall, Adama; Ly, Alioune Badara; Mercereau-Puijalon, Odile; Sakuntabhai, Anavaj; Djimdé, Abdoulaye; Maiga, Boubacar; Touré, Ousmane; Doumbo, Ogobara K; Dolo, Amagana; Troye-Blomberg, Marita; Mangano, Valentina D; Verra, Frederica; Modiano, David; Bougouma, Edith; Sirima, Sodiomon B; Ibrahim, Muntaser; Hussain, Ayman; Eid, Nahid; Elzein, Abier; Mohammed, Hiba; Elhassan, Ahmed; Elhassan, Ibrahim; Williams, Thomas N; Ndila, Carolyne; Macharia, Alexander; Marsh, Kevin; Manjurano, Alphaxard; Reyburn, Hugh; Lemnge, Martha; Ishengoma, Deus; Carter, Richard; Karunaweera, Nadira; Fernando, Deepika; Dewasurendra, Rajika; Drakeley, Christopher J; Riley, Eleanor M; Kwiatkowski, Dominic P; Rockett, Kirk A; MalariaGEN Consortium

Clonal variation in high- and low-level phenotypic and genotypic mupirocin resistance of MRSA isolates in south-east London. (2015) Hughes, John; Stabler, Richard; Gaunt, Michael; Karadag, Tacim; Desai, Nergish; Betley, Jason; Ioannou, Avgousta; Aryee, Anna; Hearn, Pasco; Marbach, Helene; Patel, Amita; Otter, Jonathan A; Edgeworth, Jonathan D; Tosas Auguet, Olga description

Association between probable postnatal depression and increased infant mortality and morbidity: findings from the DON population-based cohort study in rural Ghana. (2015) Weobong, Benedict; ten Asbroek, Augustinus HA; Soremekun, Seyi; Gram, Lu; Amenga-Etego, Seeba; Danso, Samuel; Owusu-Agyei, Seth; Prince, Martin; Kirkwood, Betty R

Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage. (2015) Peltier, Johann; Shaw, Helen A; Couchman, Edward C; Dawson, Lisa F; Yu, Lu; Choudhary, Jyoti S; Kaever, Volkhard; Wren, Brendan W; Fairweather, Neil F

Biosignatures of Exposure/Transmission and Immunity. (2015) King, Christopher L; Davies, D Huw; Felgner, Phil; Baum, Elizabeth; Jain, Aarti; Randall, Arlo; Tetteh, Kevin; Drakeley, Christopher J; Greenhouse, Bryan

Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach. (2015) Wassmer, Samuel C; Taylor, Terrie E; Rathod, Pradipsinh K; Mishra, Saroj K; Mohanty, Sanjib; Arevalo-Herrera, Myriam; Duraisingh, Manoj T; Smith, Joseph D

Transcriptional changes induced by candidate malaria vaccines and correlation with protection against malaria in a human challenge model. (2015) Dunachie, Susanna; Berthoud, Tamara; Hill, Adrian VS; Fletcher, Helen A

Profiling the host response to malaria vaccination and malaria challenge. (2015) Dunachie, Susanna; Hill, Adrian VS; Fletcher, Helen A

Submicroscopic carriage of Plasmodium falciparum and Plasmodium vivax in a low endemic area in Ethiopia where no parasitaemia was detected by microscopy or rapid diagnostic test. (2015) Tadesse, Fitsum G; Pett, Helmi; Baidjoe, Amrish; Lanke, Kjerstin; Grignard, Lynn; Sutherland, Colin; Hall, Tom; Drakeley, Chris; Bousema, Teun; Mamo, Hassen

Species-wide whole genome sequencing reveals historical global spread and recent local persistence in Shigella flexneri. (2015) Connor, Thomas R; Barker, Clare R; Baker, Kate S; Weill, François-Xavier; Talukder, Kaisar Ali; Smith, Anthony M; Baker, Stephen; Gouali, Malika; Pham Thanh, Duy; Jahan Azmi, Ishrat; Dias da Silveira, Wanderley; Semmler, Torsten; Wieler, Lothar H; Jenkins, Claire; Cravioto, Alejandro; Faruque, Shah M; Parkhill, Julian; Wook Kim, Dong; Keddy, Karen H; Thomson, Nicholas R

Profiling the host immune response to tuberculosis vaccines. (2015) Fletcher, Helen A

July 2015

Rapid Declines in Age Group-Specific Rotavirus Infection and Acute Gastroenteritis Among Vaccinated and Unvaccinated Individuals Within 1 Year of Rotavirus Vaccine Introduction in England and Wales. (2015) Atchison, Christina J; Stowe, Julia; Andrews, Nick; Collins, Sarah; Allen, David J; Nawaz, Sameena; Brown, David; Ramsay, Mary E; Ladhani, Shamez N

Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities. (2015) Helb, Danica A; Tetteh, Kevin KA; Felgner, Philip L; Skinner, Jeff; Hubbard, Alan; Arinaitwe, Emmanuel; Mayanja-Kizza, Harriet; Ssewanyana, Isaac; Kamya, Moses R; Beeson, James G; Tappero, Jordan; Smith, David L; Crompton, Peter D; Rosenthal, Philip J; Dorsey, Grant; Drakeley, Christopher J; Greenhouse, Bryan

Virulence characteristics of hcp (+) Campylobacter jejuni and Campylobacter coli isolates from retail chicken. (2015) Corcionivoschi, Nicolae; Gundogdu, Ozan; Moran, Lynn; Kelly, Carmel; Scates, Pam; Stef, Lavinia; Cean, Ada; Wren, Brendan; Dorrell, Nick; Madden, Robert H

Expanding the Entamoeba Universe: New Hosts Yield Novel Ribosomal Lineages. (2015) Jacob, Alison S; Busby, Eloise J; Levy, Abigail D; Komm, Natasha; Clark, C Graham

The Campylobacter jejuni MarR-like transcriptional regulators RrpA and RrpB both influence bacterial responses to oxidative and aerobic stresses. (2015) Gundogdu, Ozan; da Silva, Daiani T; Mohammad, Banaz; Elmi, Abdi; Mills, Dominic C; Wren, Brendan W; Dorrell, Nick

The Oral Antimalarial Drug Tafenoquine Shows Activity against Trypanosoma brucei. (2015) Carvalho, Luis; Martínez-García, Marta; Pérez-Victoria, Ignacio; Manzano, José Ignacio; Yardley, Vanessa; Gamarro, Francisco; Pérez-Victoria, José M

Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity. (2015) Duffy, Craig W; Assefa, Samuel A; Abugri, James; Amoako, Nicholas; Owusu-Agyei, Seth; Anyorigiya, Thomas; MacInnis, Bronwyn; Kwiatkowski, Dominic P; Conway, David J; Awandare, Gordon A

Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi. (2015) Glynn, Judith R; Guerra-Assunção, José Afonso; Houben, Rein MGJ; Sichali, Lifted; Mzembe, Themba; Mwaungulu, Lorrain K; Mwaungulu, J Nimrod; McNerney, Ruth; Khan, Palwasha; Parkhill, Julian; Crampin, Amelia C; Clark, Taane G

Evidence and importance of genetic exchange among field populations of Trypanosoma cruzi. (2015) Messenger, Louisa A; Miles, Michael A

Genomic Epidemiology of a Protracted Hospital Outbreak Caused by a Toxin A-Negative Clostridium difficile Sublineage PCR Ribotype 017 Strain in London, England. (2015) Cairns, MD; Preston, MD; Lawley, TD; Clark, TG; Stabler, RA; Wren, BW

Phosphoantigen Burst upon Plasmodium falciparum Schizont Rupture Can Distantly Activate Vγ9Vδ2 T Cells. (2015) Guenot, Marianne; Loizon, Séverine; Howard, Jennifer; Costa, Giulia; Baker, David A; Mohabeer, Shaneel Y; Troye-Blomberg, Marita; Moreau, Jean-François; Déchanet-Merville, Julie; Mercereau-Puijalon, Odile; Mamani-Matsuda, Maria; Behr, Charlotte

Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion. (2015) Alam, Mahmood M; Solyakov, Lev; Bottrill, Andrew R; Flueck, Christian; Siddiqui, Faiza A; Singh, Shailja; Mistry, Sharad; Viskaduraki, Maria; Lee, Kate; Hopp, Christine S; Chitnis, Chetan E; Doerig, Christian; Moon, Robert W; Green, Judith L; Holder, Anthony A; Baker, David A; Tobin, Andrew B

The Genotoxin Colibactin Is a Determinant of Virulence in Escherichia coli K1 Experimental Neonatal Systemic Infection. (2015) McCarthy, Alex J; Martin, Patricia; Cloup, Emilie; Stabler, Richard A; Oswald, Eric; Taylor, Peter W description

Dynamics of the Human Infectious Reservoir for Malaria Determined by Mosquito Feeding Assays and Ultrasensitive Malaria Diagnosis in Burkina Faso. (2015) Ouédraogo, André Lin; Gonçalves, Bronner P; Gnémé, Awa; Wenger, Edward A; Guelbeogo, Moussa W; Ouédraogo, Amathe; Gerardin, Jaline; Bever, Caitlin A; Lyons, Hil; Pitroipa, Xavier; Verhave, Jan Peter; Eckhoff, Philip A; Drakeley, Chris; Sauerwein, Robert; Luty, Adrian JF; Kouyaté, Bocar; Bousema, Teun

June 2015

'A bite before bed': exposure to malaria vectors outside the times of net use in the highlands of western Kenya. (2015) Cooke, Mary K; Kahindi, Sam C; Oriango, Robin M; Owaga, Chrispin; Ayoma, Elizabeth; Mabuka, Danspaid; Nyangau, Dennis; Abel, Lucy; Atieno, Elizabeth; Awuor, Stephen; Drakeley, Chris; Cox, Jonathan; Stevenson, Jennifer

Relationship between Distinct African Cholera Epidemics Revealed via MLVA Haplotyping of 337 Vibrio cholerae Isolates. (2015) Moore, Sandra; Miwanda, Berthe; Sadji, Adodo Yao; Thefenne, Hélène; Jeddi, Fakhri; Rebaudet, Stanislas; de Boeck, Hilde; Bidjada, Bawimodom; Depina, Jean-Jacques; Bompangue, Didier; Abedi, Aaron Aruna; Koivogui, Lamine; Keita, Sakoba; Garnotel, Eric; Plisnier, Pierre-Denis; Ruimy, Raymond; Thomson, Nicholas; Muyembe, Jean-Jacques; Piarroux, Renaud

Prospects for T. cruzi lineage-specific serological surveillance of wild mammals. (2015) Bhattacharyya, Tapan; Mills, Emily A; Jansen, Ana Maria; Miles, Michael A

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health. (2015) Holt, Kathryn E; Wertheim, Heiman; Zadoks, Ruth N; Baker, Stephen; Whitehouse, Chris A; Dance, David; Jenney, Adam; Connor, Thomas R; Hsu, Li Yang; Severin, Juliëtte; Brisse, Sylvain; Cao, Hanwei; Wilksch, Jonathan; Gorrie, Claire; Schultz, Mark B; Edwards, David J; Nguyen, Kinh Van; Nguyen, Trung Vu; Dao, Trinh Tuyet; Mensink, Martijn; Minh, Vien Le; Nhu, Nguyen Thi Khanh; Schultsz, Constance; Kuntaman, Kuntaman; Newton, Paul N; Moore, Catrin E; Strugnell, Richard A; Thomson, Nicholas R

Conditional U1 Gene Silencing in Toxoplasma gondii. (2015) Pieperhoff, Manuela S; Pall, Gurman S; Jiménez-Ruiz, Elena; Das, Sujaan; Melatti, Carmen; Gow, Matthew; Wong, Eleanor H; Heng, Joanne; Müller, Sylke; Blackman, Michael J; Meissner, Markus

Establishment of the Ivermectin Research for Malaria Elimination Network: updating the research agenda. (2015) Chaccour, Carlos J; Rabinovich, N Regina; Slater, Hannah; Canavati, Sara E; Bousema, Teun; Lacerda, Marcus; Ter Kuile, Feiko; Drakeley, Chris; Bassat, Quique; Foy, Brian D; Kobylinski, Kevin

Co-cultivation and transcriptome sequencing of two co-existing fish pathogens Moritella viscosa and Aliivibrio wodanis. (2015) Hjerde, Erik; Karlsen, Christian; Sørum, Henning; Parkhill, Julian; Willassen, Nils Peder; Thomson, Nicholas R

Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate. (2015) Seifert, Karin; Juhls, Christiane; Salguero, Francisco J; Croft, Simon L

Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay. (2015) Leba, Louis-Jérôme; Musset, Lise; Pelleau, Stéphane; Estevez, Yannick; Birer, Caroline; Briolant, Sébastien; Witkowski, Benoit; Ménard, Didier; Delves, Michael J; Legrand, Eric; Duplais, Christophe; Popovici, Jean

The draft genome of Mycobacterium aurum, a potential model organism for investigating drugs against Mycobacterium tuberculosis and Mycobacterium leprae. (2015) Phelan, Jody; Maitra, Arundhati; McNerney, Ruth; Nair, Mridul; Gupta, Antima; Coll, Francesc; Pain, Arnab; Bhakta, Sanjib; Clark, Taane G

Differential transcriptomic and metabolic profiles of M. africanum- and M. tuberculosis-infected patients after, but not before, drug treatment. (2015) Tientcheu, LD; Maertzdorf, J; Weiner, J; Adetifa, IM; Mollenkopf, H-J; Sutherland, JS; Donkor, S; Kampmann, B; Kaufmann, SHE; Dockrell, HM; Ota, MO

Mycobacterial load affects adenosine deaminase 2 levels of tuberculous pleural effusion. (2015) Kim, Chang Ho; Lee, Jaehee; Lee, Jisook; Cliff, Jacqueline M; Toulza, Frederic; Smith, Steven; Yoo, Seung Soo; Lee, Shin Yup; Cha, Seung Ick; Park, Jae Yong; Dockrell, Hazel M

Consensus on the development of vaccines against naturally acquired melioidosis. (2015) Limmathurotsakul, Direk; Funnell, Simon GP; Torres, Alfredo G; Morici, Lisa A; Brett, Paul J; Dunachie, Susanna; Atkins, Timothy; Altmann, Daniel M; Bancroft, Gregory; Peacock, Sharon J; Steering Group on Melioidosis Vaccine Development

May 2015

Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae. (2015) Bossé, Janine T; Li, Yanwen; Atherton, Tom G; Walker, Stephanie; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

Admixture in Humans of Two Divergent Plasmodium knowlesi Populations Associated with Different Macaque Host Species. (2015) Divis, Paul CS; Singh, Balbir; Anderios, Fread; Hisam, Shamilah; Matusop, Asmad; Kocken, Clemens H; Assefa, Samuel A; Duffy, Craig W; Conway, David J

Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences. (2015) Coll, Francesc; McNerney, Ruth; Preston, Mark D; Guerra-Assunção, José Afonso; Warry, Andrew; Hill-Cawthorne, Grant; Mallard, Kim; Nair, Mridul; Miranda, Anabela; Alves, Adriana; Perdigão, João; Viveiros, Miguel; Portugal, Isabel; Hasan, Zahra; Hasan, Rumina; Glynn, Judith R; Martin, Nigel; Pain, Arnab; Clark, Taane G

Development of reverse genetics for Ibaraki virus to produce viable VP6-tagged IBAV. (2015) Matsuo, Eiko; Saeki, Keiichi; Roy, Polly; Kawano, Junichi

Focal Screening to Identify the Subpatent Parasite Reservoir in an Area of Low and Heterogeneous Transmission in the Kenya Highlands. (2015) Stresman, Gillian H; Baidjoe, Amrish Y; Stevenson, Jennifer; Grignard, Lynn; Odongo, Wycliffe; Owaga, Chrispin; Osoti, Victor; Makori, Euniah; Shagari, Shehu; Marube, Elisabeth; Cox, Jonathan; Drakeley, Chris; Bousema, Teun

Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging. (2015) Francisco, Amanda Fortes; Lewis, Michael D; Jayawardhana, Shiromani; Taylor, Martin C; Chatelain, Eric; Kelly, John M

Application of RNAi to Genomic Drug Target Validation in Schistosomes. (2015) Guidi, Alessandra; Mansour, Nuha R; Paveley, Ross A; Carruthers, Ian M; Besnard, Jérémy; Hopkins, Andrew L; Gilbert, Ian H; Bickle, Quentin D

FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure. (2015) Sullivan, Richard T; Kim, Charles C; Fontana, Mary F; Feeney, Margaret E; Jagannathan, Prasanna; Boyle, Michelle J; Drakeley, Chris J; Ssewanyana, Isaac; Nankya, Felistas; Mayanja-Kizza, Harriet; Dorsey, Grant; Greenhouse, Bryan

Lifestyle, attitudes and needs of uncured XDR-TB patients living in the communities of South Africa: a qualitative study. (2015) Senthilingam, Meera; Pietersen, Elize; McNerney, Ruth; Te Riele, Julian; Sedres, Pat; Wilson, Ruth; Dheda, Keertan

The Classification and Evolution of Enzyme Function. (2015) Martínez Cuesta, Sergio; Rahman, Syed Asad; Furnham, Nicholas; Thornton, Janet M

Assessing the infectious reservoir of falciparum malaria: past and future. (2015) Stone, Will; Gonçalves, Bronner P; Bousema, Teun; Drakeley, Chris

Influence of cellular trafficking pathway on bluetongue virus infection in ovine cells. (2015) Bhattacharya, Bishnupriya; Celma, Cristina C; Roy, Polly

Erratum: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2015) Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Chau, Nguyen Van Vinh; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium

Geostatistical modeling of malaria endemicity using serological indicators of exposure collected through school surveys. (2015) Ashton, Ruth A; Kefyalew, Takele; Rand, Alison; Sime, Heven; Assefa, Ashenafi; Mekasha, Addis; Edosa, Wasihun; Tesfaye, Gezahegn; Cano, Jorge; Teka, Hiwot; Reithinger, Richard; Pullan, Rachel L; Drakeley, Chris J; Brooker, Simon J

The impact of maternal infection with Mycobacterium tuberculosis on the infant response to bacille Calmette-Guérin immunization. (2015) Mawa, Patrice A; Nkurunungi, Gyaviira; Egesa, Moses; Webb, Emily L; Smith, Steven G; Kizindo, Robert; Akello, Mirriam; Lule, Swaib A; Muwanga, Moses; Dockrell, Hazel M; Cose, Stephen; Elliott, Alison M

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events. (2015) Wong, Vanessa K; Baker, Stephen; Pickard, Derek J; Parkhill, Julian; Page, Andrew J; Feasey, Nicholas A; Kingsley, Robert A; Thomson, Nicholas R; Keane, Jacqueline A; Weill, François-Xavier; Edwards, David J; Hawkey, Jane; Harris, Simon R; Mather, Alison E; Cain, Amy K; Hadfield, James; Hart, Peter J; Thieu, Nga Tran Vu; Klemm, Elizabeth J; Glinos, Dafni A; Breiman, Robert F; Watson, Conall H; Kariuki, Samuel; Gordon, Melita A; Heyderman, Robert S; Okoro, Chinyere; Jacobs, Jan; Lunguya, Octavie; Edmunds, W John; Msefula, Chisomo; Chabalgoity, Jose A; Kama, Mike; Jenkins, Kylie; Dutta, Shanta; Marks, Florian; Campos, Josefina; Thompson, Corinne; Obaro, Stephen; MacLennan, Calman A; Dolecek, Christiane; Keddy, Karen H; Smith, Anthony M; Parry, Christopher M; Karkey, Abhilasha; Mulholland, E Kim; Campbell, James I; Dongol, Sabina; Basnyat, Buddha; Dufour, Muriel; Bandaranayake, Don; Naseri, Take Toleafoa; Singh, Shalini Pravin; Hatta, Mochammad; Newton, Paul; Onsare, Robert S; Isaia, Lupeoletalalei; Dance, David; Davong, Viengmon; Thwaites, Guy; Wijedoru, Lalith; Crump, John A; De Pinna, Elizabeth; Nair, Satheesh; Nilles, Eric J; Thanh, Duy Pham; Turner, Paul; Soeng, Sona; Valcanis, Mary; Powling, Joan; Dimovski, Karolina; Hogg, Geoff; Farrar, Jeremy; Holt, Kathryn E; Dougan, Gordon

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae. (2015) Bossé, Janine T; Li, Yanwen; Walker, Stephanie; Atherton, Tom; Fernandez Crespo, Roberto; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Oshota, Olusegun; Holden, Matt TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T Consortium

Contrasting Transmission Dynamics of Co-endemic Plasmodium vivax and P. falciparum: Implications for Malaria Control and Elimination. (2015) Noviyanti, Rintis; Coutrier, Farah; Utami, Retno AS; Trimarsanto, Hidayat; Tirta, Yusrifar K; Trianty, Leily; Kusuma, Andreas; Sutanto, Inge; Kosasih, Ayleen; Kusriastuti, Rita; Hawley, William A; Laihad, Ferdinand; Lobo, Neil; Marfurt, Jutta; Clark, Taane G; Price, Ric N; Auburn, Sarah

cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. (2015) Ramdani, Ghania; Naissant, Bernina; Thompson, Eloise; Breil, Florence; Lorthiois, Audrey; Dupuy, Florian; Cummings, Ross; Duffier, Yoann; Corbett, Yolanda; Mercereau-Puijalon, Odile; Vernick, Kenneth; Taramelli, Donatella; Baker, David A; Langsley, Gordon; Lavazec, Catherine

Big Data in Vaccinology: Introduction and section summaries. (2015) Kaufmann, Stefan HE; Fletcher, Helen A; Guzmán, Carlos A; Ottenhoff, Tom HM

"Benznidazole-resistance in Trypanosoma cruzi: Evidence that distinct mechanisms can act in concert'' [Mol. Biochem. Parasit. (2014) 193, 17-19]. (2015) Campos, MCO; Leon, LL; Taylor, MC; Kelly, JM

April 2015

Temporal changes in nasopharyngeal carriage of Streptococcus pneumoniae serotype 1 genotypes in healthy Gambians before and after the 7-valent pneumococcal conjugate vaccine. (2015) Ebruke, Chinelo; Roca, Anna; Egere, Uzochukwu; Darboe, Ousainou; Hill, Philip C; Greenwood, Brian; Wren, Brendan W; Adegbola, Richard A; Antonio, Martin

Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. (2015) Riede, O; Seifert, K; Oswald, D; Endmann, A; Hock, C; Winkler, A; Salguero, FJ; Schroff, M; Croft, SL; Juhls, C

Imputation-based population genetics analysis of Plasmodium falciparum malaria parasites. (2015) Samad, Hanif; Coll, Francesc; Preston, Mark D; Ocholla, Harold; Fairhurst, Rick M; Clark, Taane G

Serological evidence of vector and parasite exposure in Southern Ghana: the dynamics of malaria transmission intensity. (2015) Badu, Kingsley; Gyan, Ben; Appawu, Maxwell; Mensah, Daniel; Dodoo, Daniel; Yan, Guiyun; Drakeley, Chris; Zhou, Guofa; Owusu-Dabo, Ellis; Koram, Kwadwo Ansah

Persistence of chloroquine-resistant haplotypes of Plasmodium falciparum in children with uncomplicated Malaria in Lagos, Nigeria, four years after change of chloroquine as first-line antimalarial medicine. (2015) Oladipo, Oladosu O; Wellington, Oyibo A; Sutherland, Colin J

Intercontinental dissemination of azithromycin-resistant shigellosis through sexual transmission: a cross-sectional study. (2015) Baker, Kate S; Dallman, Timothy J; Ashton, Philip M; Day, Martin; Hughes, Gwenda; Crook, Paul D; Gilbart, Victoria L; Zittermann, Sandra; Allen, Vanessa G; Howden, Benjamin P; Tomita, Takehiro; Valcanis, Mary; Harris, Simon R; Connor, Thomas R; Sintchenko, Vitali; Howard, Peter; Brown, Jeremy D; Petty, Nicola K; Gouali, Malika; Thanh, Duy Pham; Keddy, Karen H; Smith, Anthony M; Talukder, Kaisar A; Faruque, Shah M; Parkhill, Julian; Baker, Stephen; Weill, François-Xavier; Jenkins, Claire; Thomson, Nicholas R

Randomized Noninferiority Trial of Dihydroartemisinin-Piperaquine Compared with Sulfadoxine-Pyrimethamine plus Amodiaquine for Seasonal Malaria Chemoprevention in Burkina Faso. (2015) Zongo, Issaka; Milligan, Paul; Compaore, Yves Daniel; Some, A Fabrice; Greenwood, Brian; Tarning, Joel; Rosenthal, Philip J; Sutherland, Colin; Nosten, Francois; Ouedraogo, Jean-Bosco

Ecological host fitting of Trypanosoma cruzi TcI in Bolivia: mosaic population structure, hybridization and a role for humans in Andean parasite dispersal. (2015) Messenger, Louisa A; Garcia, Lineth; Vanhove, Mathieu; Huaranca, Carlos; Bustamante, Marinely; Torrico, Marycruz; Torrico, Faustino; Miles, Michael A; Llewellyn, Martin S

In-vitro sensitivity of Pakistani Leishmania tropica field isolate against buparvaquone in comparison to standard anti-leishmanial drugs. (2015) Jamal, Qaisar; Khan, Nazma Habib; Wahid, Sobia; Awan, Mahwish Mustafa; Sutherland, Colin; Shah, Akram

Chemical and bioassay techniques to authenticate quality of the anti-leishmanial drug miltefosine. (2015) Kaur, Harparkash; Seifert, Karin; Hawkes, Geoffrey E; Coumbarides, Gregory S; Alvar, Jorge; Croft, Simon L

Biogenesis of the crystalloid organelle in Plasmodium involves microtubule-dependent vesicle transport and assembly. (2015) Saeed, Sadia; Tremp, Annie Z; Dessens, Johannes T

Variation in Plasmodium falciparum erythrocyte invasion phenotypes and merozoite ligand gene expression across different populations in areas of malaria endemicity. (2015) Bowyer, Paul W; Stewart, Lindsay B; Aspeling-Jones, Harvey; Mensah-Brown, Henrietta E; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Awandare, Gordon A; Conway, David J

The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence. (2015) Taylor, Martin C; Lewis, Michael D; Fortes Francisco, Amanda; Wilkinson, Shane R; Kelly, John M

Evaluating the effect of innovative motivation and supervision approaches on community health worker performance and retention in Uganda and Mozambique: study protocol for a randomised controlled trial. (2015) Källander, Karin; Strachan, Daniel; Soremekun, Seyi; Hill, Zelee; Lingam, Raghu; Tibenderana, James; Kasteng, Frida; Vassall, Anna; Meek, Sylvia; Kirkwood, Betty

Malaria resistance to non-artemisinin partner drugs: how to reACT. (2015) van Schalkwyk, Donelly A; Sutherland, Colin J

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system. (2015) Bottai, Daria; Frigui, Wafa; Clark, Simon; Rayner, Emma; Zelmer, Andrea; Andreu, Nuria; de Jonge, Marien I; Bancroft, Gregory J; Williams, Ann; Brodin, Priscille; Brosch, Roland

Naturally acquired antibody responses to recombinant Pfs230 and Pfs48/45 transmission blocking vaccine candidates. (2015) Jones, Sophie; Grignard, Lynn; Nebie, Issa; Chilongola, Jaffu; Dodoo, Daniel; Sauerwein, Robert; Theisen, Michael; Roeffen, Will; Singh, Shrawan Kumar; Singh, Rajesh Kumar; Singh, Sanjay; Kyei-Baafour, Eric; Tetteh, Kevin; Drakeley, Chris; Bousema, Teun

Investigating the non-specific effects of BCG vaccination on the innate immune system in Ugandan neonates: study protocol for a randomised controlled trial. (2015) Prentice, Sarah; Webb, Emily L; Dockrell, Hazel M; Kaleebu, Pontiano; Elliott, Alison M; Cose, Stephen

T Cell Immunity to the Alkyl Hydroperoxide Reductase of Burkholderia pseudomallei: A Correlate of Disease Outcome in Acute Melioidosis. (2015) Reynolds, Catherine; Goudet, Amélie; Jenjaroen, Kemajittra; Sumonwiriya, Manutsanun; Rinchai, Darawan; Musson, Julie; Overbeek, Saskia; Makinde, Julia; Quigley, Kathryn; Manji, Jiten; Spink, Natasha; Yos, Pagnarith; Wuthiekanun, Vanaporn; Bancroft, Gregory; Robinson, John; Lertmemongkolchai, Ganjana; Dunachie, Susanna; Maillere, Bernard; Holden, Matthew; Altmann, Daniel; Boyton, Rosemary

Extensive Capsule Locus Variation and Large-Scale Genomic Recombination within the Klebsiella pneumoniae Clonal Group 258. (2015) Wyres, Kelly L; Gorrie, Claire; Edwards, David J; Wertheim, Heiman FL; Hsu, Li Yang; Van Kinh, Nguyen; Zadoks, Ruth; Baker, Stephen; Holt, Kathryn E

A novel multiple-stage antimalarial agent that inhibits protein synthesis. (2015) Baragaña, Beatriz; Hallyburton, Irene; Lee, Marcus CS; Norcross, Neil R; Grimaldi, Raffaella; Otto, Thomas D; Proto, William R; Blagborough, Andrew M; Meister, Stephan; Wirjanata, Grennady; Ruecker, Andrea; Upton, Leanna M; Abraham, Tara S; Almeida, Mariana J; Pradhan, Anupam; Porzelle, Achim; Luksch, Torsten; Martínez, María Santos; Luksch, Torsten; Bolscher, Judith M; Woodland, Andrew; Norval, Suzanne; Zuccotto, Fabio; Thomas, John; Simeons, Frederick; Stojanovski, Laste; Osuna-Cabello, Maria; Brock, Paddy M; Churcher, Tom S; Sala, Katarzyna A; Zakutansky, Sara E; Jiménez-Díaz, María Belén; Sanz, Laura Maria; Riley, Jennifer; Basak, Rajshekhar; Campbell, Michael; Avery, Vicky M; Sauerwein, Robert W; Dechering, Koen J; Noviyanti, Rintis; Campo, Brice; Frearson, Julie A; Angulo-Barturen, Iñigo; Ferrer-Bazaga, Santiago; Gamo, Francisco Javier; Wyatt, Paul G; Leroy, Didier; Siegl, Peter; Delves, Michael J; Kyle, Dennis E; Wittlin, Sergio; Marfurt, Jutta; Price, Ric N; Sinden, Robert E; Winzeler, Elizabeth A; Charman, Susan A; Bebrevska, Lidiya; Gray, David W; Campbell, Simon; Fairlamb, Alan H; Willis, Paul A; Rayner, Julian C; Fidock, David A; Read, Kevin D; Gilbert, Ian H

Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients. (2015) Llewellyn, Martin S; Messenger, Louisa A; Luquetti, Alejandro O; Garcia, Lineth; Torrico, Faustino; Tavares, Suelene BN; Cheaib, Bachar; Derome, Nicolas; Delepine, Marc; Baulard, Céline; Deleuze, Jean-Francois; Sauer, Sascha; Miles, Michael A

Sample size determination for estimating antibody seroconversion rate under stable malaria transmission intensity. (2015) Sepúlveda, Nuno; Drakeley, Chris

Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across 3 Malaria-Endemic Areas in Ghana. (2015) Mensah-Brown, Henrietta E; Amoako, Nicholas; Abugri, James; Stewart, Lindsay B; Agongo, Godfred; Dickson, Emmanuel K; Ofori, Michael F; Stoute, José A; Conway, David J; Awandare, Gordon A

Multidrug-resistant Salmonella enterica serotype Typhi, Gulf of Guinea Region, Africa. (2015) Baltazar, Murielle; Ngandjio, Antoinette; Holt, Kathryn Elizabeth; Lepillet, Elodie; Pardos de la Gandara, Maria; Collard, Jean-Marc; Bercion, Raymond; Nzouankeu, Ariane; Le Hello, Simon; Dougan, Gordon; Fonkoua, Marie-Christine; Weill, François-Xavier

Carbapenem and amikacin resistance on a large conjugative Acinetobacter baumannii plasmid. (2015) Nigro, Steven J; Holt, Kathryn E; Pickard, Derek; Hall, Ruth M

A genomic island integrated into recA of Vibrio cholerae contains a divergent recA and provides multi-pathway protection from DNA damage. (2015) Rapa, Rita A; Islam, Atiqul; Monahan, Leigh G; Mutreja, Ankur; Thomson, Nicholas; Charles, Ian G; Stokes, Harold W; Labbate, Maurizio

March 2015

Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. (2015) Weinert, Lucy A; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah E; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad; Howell, Kate J; Vehkala, Minna; Välimäki, Niko; Harris, David; Chieu, Tran Thi Bich; Van Vinh Chau, Nguyen; Campbell, James; Schultsz, Constance; Parkhill, Julian; Bentley, Stephen D; Langford, Paul R; Rycroft, Andrew N; Wren, Brendan W; Farrar, Jeremy; Baker, Stephen; Hoa, Ngo Thi; Holden, Matthew TG; Tucker, Alexander W; Maskell, Duncan J; BRaDP1T Consortium

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data. (2015) WorldWide Antimalarial Resistance Network (WWARN) AS-AQ Study Gr; Adjuik, Martin A; Allan, Richard; Anvikar, Anupkumar R; Ashley, Elizabeth A; Ba, Mamadou S; Barennes, Hubert; Barnes, Karen I; Bassat, Quique; Baudin, Elisabeth; Björkman, Anders; Bompart, François; Bonnet, Maryline; Borrmann, Steffen; Brasseur, Philippe; Bukirwa, Hasifa; Checchi, Francesco; Cot, Michel; Dahal, Prabin; D'Alessandro, Umberto; Deloron, Philippe; Desai, Meghna; Diap, Graciela; Djimde, Abdoulaye A; Dorsey, Grant; Doumbo, Ogobara K; Espié, Emmanuelle; Etard, Jean-Francois; Fanello, Caterina I; Faucher, Jean-François; Faye, Babacar; Flegg, Jennifer A; Gaye, Oumar; Gething, Peter W; González, Raquel; Grandesso, Francesco; Guerin, Philippe J; Guthmann, Jean-Paul; Hamour, Sally; Hasugian, Armedy Ronny; Hay, Simon I; Humphreys, Georgina S; Jullien, Vincent; Juma, Elizabeth; Kamya, Moses R; Karema, Corine; Kiechel, Jean R; Kremsner, Peter G; Krishna, Sanjeev; Lameyre, Valérie; Ibrahim, Laminou M; Lee, Sue J; Lell, Bertrand; Mårtensson, Andreas; Massougbodji, Achille; Menan, Hervé; Ménard, Didier; Menéndez, Clara; Meremikwu, Martin; Moreira, Clarissa; Nabasumba, Carolyn; Nambozi, Michael; Ndiaye, Jean-Louis; Nikiema, Frederic; Nsanzabana, Christian; Ntoumi, Francine; Ogutu, Bernhards R; Olliaro, Piero; Osorio, Lyda; Ouédraogo, Jean-Bosco; Penali, Louis K; Pene, Mbaye; Pinoges, Loretxu; Piola, Patrice; Price, Ric N; Roper, Cally; Rosenthal, Philip J; Rwagacondo, Claude Emile; Same-Ekobo, Albert; Schramm, Birgit; Seck, Amadou; Sharma, Bhawna; Sibley, Carol Hopkins; Sinou, Véronique; Sirima, Sodiomon B; Smith, Jeffery J; Smithuis, Frank; Somé, Fabrice A; Sow, Doudou; Staedke, Sarah G; Stepniewska, Kasia; Swarthout, Todd D; Sylla, Khadime; Talisuna, Ambrose O; Tarning, Joel; Taylor, Walter RJ; Temu, Emmanuel A; Thwing, Julie I; Tjitra, Emiliana; Tine, Roger CK; Tinto, Halidou; Vaillant, Michel T; Valecha, Neena; Van den Broek, Ingrid; White, Nicholas J; Yeka, Adoke; Zongo, Issaka

Genetic recombination between human and animal parasites creates novel strains of human pathogen. (2015) Gibson, Wendy; Peacock, Lori; Ferris, Vanessa; Fischer, Katrin; Livingstone, Jennifer; Thomas, James; Bailey, Mick

Human helminth therapy to treat inflammatory disorders - where do we stand? (2015) Helmby, Helena

Current methods for capsular typing of Streptococcus pneumoniae. (2015) Jauneikaite, Elita; Tocheva, Anna S; Jefferies, Johanna MC; Gladstone, Rebecca A; Faust, Saul N; Christodoulides, Myron; Hibberd, Martin L; Clarke, Stuart C

The effect of daily co-trimoxazole prophylaxis on natural development of antibody-mediated immunity against P. falciparum malaria infection in HIV-exposed uninfected Malawian children. (2015) Longwe, Herbert; Jambo, Kondwani C; Phiri, Kamija S; Mbeye, Nyanyiwe; Gondwe, Thandile; Hall, Tom; Tetteh, Kevin KA; Drakeley, Chris; Mandala, Wilson L

USP38, FREM3, SDC1, DDC, and LOC727982 Gene Polymorphisms and Differential Susceptibility to Severe Malaria in Tanzania. (2015) Manjurano, Alphaxard; Sepúlveda, Nuno; Nadjm, Behzad; Mtove, George; Wangai, Hannah; Maxwell, Caroline; Olomi, Raimos; Reyburn, Hugh; Drakeley, Christopher J; Riley, Eleanor M; Clark, Taane G; in Collaboration With MalariaGEN

Dimorphism in genes encoding sexual-stage proteins of Plasmodium ovale curtisi and Plasmodium ovale wallikeri. (2015) Oguike, Mary C; Sutherland, Colin J

Programmed death ligand 1 on Burkholderia pseudomallei-infected human polymorphonuclear neutrophils impairs T cell functions. (2015) Buddhisa, Surachat; Rinchai, Darawan; Ato, Manabu; Bancroft, Gregory J; Lertmemongkolchai, Ganjana

Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation. (2015) Miguel-Blanco, Celia; Lelièvre, Joël; Delves, Michael J; Bardera, Ana I; Presa, Jesús L; López-Barragán, María José; Ruecker, Andrea; Marques, Sara; Sinden, Robert E; Herreros, Esperanza

The Plasmodium Class XIV Myosin, MyoB, Has a Distinct Subcellular Location in Invasive and Motile Stages of the Malaria Parasite and an Unusual Light Chain. (2015) Yusuf, Noor A; Green, Judith L; Wall, Richard J; Knuepfer, Ellen; Moon, Robert W; Schulte-Huxel, Christina; Stanway, Rebecca R; Martin, Stephen R; Howell, Steven A; Douse, Christopher H; Cota, Ernesto; Tate, Edward W; Tewari, Rita; Holder, Anthony A

Sensitive detection of chromatin-altering polymorphisms reveals autoimmune disease mechanisms. (2015) del Rosario, Ricardo Cruz-Herrera; Poschmann, Jeremie; Rouam, Sigrid Laure; Png, Eileen; Khor, Chiea Chuen; Hibberd, Martin Lloyd; Prabhakar, Shyam

Novel R pipeline for analyzing Biolog Phenotypic MicroArray data. (2015) Vehkala, Minna; Shubin, Mikhail; Connor, Thomas R; Thomson, Nicholas R; Corander, Jukka

Association between recent internal travel and malaria in Ugandan highland and highland fringe areas. (2015) Lynch, Caroline A; Bruce, Jane; Bhasin, Amit; Roper, Cally; Cox, Jonathan; Abeku, Tarekegn A

Malaria transmission, infection, and disease at three sites with varied transmission intensity in Uganda: implications for malaria control. (2015) Kamya, Moses R; Arinaitwe, Emmanuel; Wanzira, Humphrey; Katureebe, Agaba; Barusya, Chris; Kigozi, Simon P; Kilama, Maxwell; Tatem, Andrew J; Rosenthal, Philip J; Drakeley, Chris; Lindsay, Steve W; Staedke, Sarah G; Smith, David L; Greenhouse, Bryan; Dorsey, Grant

Factors associated with malaria parasitemia, anemia and serological responses in a spectrum of epidemiological settings in Uganda. (2015) Yeka, Adoke; Nankabirwa, Joaniter; Mpimbaza, Arthur; Kigozi, Ruth; Arinaitwe, Emmanuel; Drakeley, Chris; Greenhouse, Bryan; Kamya, Moses R; Dorsey, Grant; Staedke, Sarah G

Molecular detection identified a type six secretion system in Campylobacter jejuni from various sources but not from human cases. (2015) Siddiqui, F; Champion, O; Akram, M; Studholme, D; Eqani, SAMAS; Wren, BW; Titball, R; Bokhari, H

Convergent adaptation in the dominant global hospital clone ST239 of methicillin-resistant Staphylococcus aureus. (2015) Baines, Sarah L; Holt, Kathryn E; Schultz, Mark B; Seemann, Torsten; Howden, Brian O; Jensen, Slade O; van Hal, Sebastiaan J; Coombs, Geoffrey W; Firth, Neville; Powell, David R; Stinear, Timothy P; Howden, Benjamin P

Large-scale whole genome sequencing of M. tuberculosis provides insights into transmission in a high prevalence area. (2015) Guerra-Assunção, JA; Crampin, AC; Houben, RMGJ; Mzembe, T; Mallard, K; Coll, F; Khan, P; Banda, L; Chiwaya, A; Pereira, RPA; McNerney, R; Fine, PEM; Parkhill, J; Clark, TG; Glynn, JR

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. (2015) Herbst, Susanne; Shah, Anand; Mazon Moya, Maria; Marzola, Vanessa; Jensen, Barbara; Reed, Anna; Birrell, Mark A; Saijo, Shinobu; Mostowy, Serge; Shaunak, Sunil; Armstrong-James, Darius

The gametocytocidal efficacy of primaquine in malaria asymptomatic carriers treated with dihydroartemisinin-piperaquine in The Gambia (PRINOGAM): study protocol for a randomised controlled trial. (2015) Okebe, Joseph; Bousema, Teun; Affara, Muna; DiTanna, GianLuca; Eziefula, Alice C; Jawara, Musa; Nwakanma, Davis; Amambua-Ngwa, Alfred; Van Geertruyden, Jean-Pierre; Drakeley, Chris; D'Alessandro, Umberto

February 2015

Whole genome sequencing based characterization of extensively drug-resistant Mycobacterium tuberculosis isolates from Pakistan. (2015) Ali, Asho; Hasan, Zahra; McNerney, Ruth; Mallard, Kim; Hill-Cawthorne, Grant; Coll, Francesc; Nair, Mridul; Pain, Arnab; Clark, Taane G; Hasan, Rumina

Serology for trachoma surveillance after cessation of mass drug administration. (2015) Martin, Diana L; Bid, Rhiannon; Sandi, Frank; Goodhew, E Brook; Massae, Patrick A; Lasway, Augustin; Philippin, Heiko; Makupa, William; Molina, Sandra; Holland, Martin J; Mabey, David CW; Drakeley, Chris; Lammie, Patrick J; Solomon, Anthony W

Structure-based identification of functional residues in the nucleoside-2'-O-methylase domain of Bluetongue virus VP4 capping enzyme. (2015) Stewart, Meredith E; Roy, Polly

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria. (2015) Boyle, Michelle J; Reiling, Linda; Feng, Gaoqian; Langer, Christine; Osier, Faith H; Aspeling-Jones, Harvey; Cheng, Yik Sheng; Stubbs, Janine; Tetteh, Kevin KA; Conway, David J; McCarthy, James S; Muller, Ivo; Marsh, Kevin; Anders, Robin F; Beeson, James G

The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine. (2015) Henriques, Gisela; van Schalkwyk, Donelly A; Burrow, Rebekah; Warhurst, David C; Thompson, Eloise; Baker, David A; Fidock, David A; Hallett, Rachel; Flueck, Christian; Sutherland, Colin J

Genome Sequences of Three Salmonella enterica subsp. enterica Serovar Infantis Strains from Healthy Broiler Chicks in Hungary and in the United Kingdom. (2015) Olasz, Ferenc; Nagy, Tibor; Szabó, Móni; Kiss, János; Szmolka, Ama; Barta, Endre; van Tonder, Andries; Thomson, Nicholas; Barrow, Paul; Nagy, Béla

African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania. (2015) Manjurano, Alphaxard; Sepulveda, Nuno; Nadjm, Behzad; Mtove, George; Wangai, Hannah; Maxwell, Caroline; Olomi, Raimos; Reyburn, Hugh; Riley, Eleanor M; Drakeley, Christopher J; Clark, Taane G; MalariaGEN Consortium

Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle. (2015) Stallmach, Robert; Kavishwar, Manoli; Withers-Martinez, Chrislaine; Hackett, Fiona; Collins, Christine R; Howell, Steven A; Yeoh, Sharon; Knuepfer, Ellen; Atid, Avshalom J; Holder, Anthony A; Blackman, Michael J

Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. (2015) Nalwoga, Angela; Cose, Stephen; Wakeham, Katie; Miley, Wendell; Ndibazza, Juliet; Drakeley, Christopher; Elliott, Alison; Whitby, Denise; Newton, Robert

Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria in the setting of three different chemopreventive regimens. (2015) Kapisi, James; Bigira, Victor; Clark, Tamara; Kinara, Stephen; Mwangwa, Florence; Achan, Jane; Kamya, Moses; Soremekun, Seyi; Dorsey, Grant

Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection. (2015) Farnell, Edward J; Tyagi, Nidhi; Ryan, Stephanie; Chalmers, Iain W; Pinot de Moira, Angela; Jones, Frances M; Wawrzyniak, Jakub; Fitzsimmons, Colin M; Tukahebwa, Edridah M; Furnham, Nicholas; Maizels, Rick M; Dunne, David W

Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress. (2015) Kim, Jeong Joo; Flueck, Christian; Franz, Eugen; Sanabria-Figueroa, Eduardo; Thompson, Eloise; Lorenz, Robin; Bertinetti, Daniela; Baker, David A; Herberg, Friedrich W; Kim, Choel

Deletion of zmp1 improves Mycobacterium bovis BCG-mediated protection in a guinea pig model of tuberculosis. (2015) Sander, Peter; Clark, Simon; Petrera, Agnese; Vilaplana, Cristina; Meuli, Michael; Selchow, Petra; Zelmer, Andrea; Mohanan, Deepa; Andreu, Nuria; Rayner, Emma; Dal Molin, Michael; Bancroft, Gregory J; Johansen, Pål; Cardona, Pere-Joan; Williams, Ann; Böttger, Erik C

January 2015

Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity. (2015) Sola, Irene; Castellà, Sílvia; Viayna, Elisabet; Galdeano, Carles; Taylor, Martin C; Gbedema, Stephen Y; Pérez, Belén; Clos, M Victòria; Jones, Deuan C; Fairlamb, Alan H; Wright, Colin W; Kelly, John M; Muñoz-Torrero, Diego

Paths to a malaria vaccine illuminated by parasite genomics. (2015) Conway, David J

Characterization of genomic variations in SNPs of PE_PGRS genes reveals deletions and insertions in extensively drug resistant (XDR) M. tuberculosis strains from Pakistan. (2015) Kanji, Akbar; Hasan, Zahra; Ali, Asho; McNerney, Ruth; Mallard, Kim; Coll, Francesc; Hill-Cawthorne, Grant; Nair, Mridul; Clark, Taane G; Zaver, Ambreen; Jafri, Sana; Hasan, Rumina

Remarkable diversity of intron-1 of the para voltage-gated sodium channel gene in an Anopheles gambiae/Anopheles coluzzii hybrid zone. (2015) Santolamazza, Federica; Caputo, Beniamino; Nwakanma, Davis C; Fanello, Caterina; Petrarca, Vincenzo; Conway, David J; Weetman, David; Pinto, Joao; Mancini, Emiliano; della Torre, Alessandra

The impact of childhood vaccines on bacterial carriage in the nasopharynx: a longitudinal study. (2015) Bottomley, Christian; Bojang, Abdoulie; Smith, Peter G; Darboe, Ousainou; Antonio, Martin; Foster-Nyarko, Ebenezer; Kampmann, Beate; Greenwood, Brian; D'Alessandro, Umberto; Roca, Anna

Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty. (2015) Carnes, Jason; Anupama, Atashi; Balmer, Oliver; Jackson, Andrew; Lewis, Michael; Brown, Rob; Cestari, Igor; Desquesnes, Marc; Gendrin, Claire; Hertz-Fowler, Christiane; Imamura, Hideo; Ivens, Alasdair; Kořený, Luděk; Lai, De-Hua; MacLeod, Annette; McDermott, Suzanne M; Merritt, Chris; Monnerat, Severine; Moon, Wonjong; Myler, Peter; Phan, Isabelle; Ramasamy, Gowthaman; Sivam, Dhileep; Lun, Zhao-Rong; Lukeš, Julius; Stuart, Ken; Schnaufer, Achim

Gradual acquisition of immunity to severe malaria with increasing exposure. (2015) Griffin, Jamie T; Hollingsworth, T Déirdre; Reyburn, Hugh; Drakeley, Chris J; Riley, Eleanor M; Ghani, Azra C ['material/summary:fileicon_application/x-zip-compressed' not defined]

Genome Sequence of Acinetobacter baumannii Strain A1, an Early Example of Antibiotic-Resistant Global Clone 1. (2015) Holt, Kathryn E; Hamidian, Mohammad; Kenyon, Johanna J; Wynn, Matthew T; Hawkey, Jane; Pickard, Derek; Hall, Ruth M

Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches. (2015) Sahu, Praveen K; Satpathi, Sanghamitra; Behera, Prativa K; Mishra, Saroj K; Mohanty, Sanjib; Wassmer, Samuel Crocodile

2015

Subverting lysosomal function in Trypanosoma brucei. (2015) Alsford, Sam

PhyTB: Phylogenetic tree visualisation and sample positioning for M. tuberculosis. (2015) Benavente, Ernest D; Coll, Francesc; Furnham, Nick; McNerney, Ruth; Glynn, Judith R; Campino, Susana; Pain, Arnab; Mohareb, Fady R; Clark, Taane G

Corrigendum to ‘Characterisation of a mobilisable plasmid conferring florfenicol and chloramphenicol resistance in Actinobacillus pleuropneumoniae’ [Veterinary Microbiology 178 (2015) 279–282]. (2015) Bossé, Janine T; Li, Yanwen; Atherton, Tom G; Walker, Stephanie; Williamson, Susanna M; Rogers, Jon; Chaudhuri, Roy R; Weinert, Lucy A; Holden, Matthew TG; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R

A high-resolution genomic analysis of multidrug-resistant hospital outbreaks of Klebsiella pneumoniae. (2015) Chung The, Hao; Karkey, Abhilasha; Pham Thanh, Duy; Boinett, Christine J; Cain, Amy K; Ellington, Matthew; Baker, Kate S; Dongol, Sabina; Thompson, Corinne; Harris, Simon R; Jombart, Thibaut; Le Thi Phuong, Tu; Tran Do Hoang, Nhu; Ha Thanh, Tuyen; Shretha, Shrijana; Joshi, Suchita; Basnyat, Buddha; Thwaites, Guy; Thomson, Nicholas R; Rabaa, Maia A; Baker, Stephen

The Nobel Prize in Medicine 2015: Two drugs that changed global health. (2015) Croft, Simon L; Ward, Steven

Multidrug-Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage, Wrongly Identified as Mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), Causing Active Tuberculosis in South Brazil. (2015) Dalla Costa, Elis R; Vasconcelos, Sidra EG; Esteves, Leonardo S; Gomes, Harrison M; Gomes, Lia L; da Silva, Pedro Almeida; Perdigão, João; Portugal, Isabel; Viveiros, Miguel; McNerney, Ruth; Pain, Arnab; Clark, Taane G; Rastogi, Nalin; Unis, Gisela; Rossetti, Maria Lucia R; Suffys, Philip Noel

Evaluating the impact of pulse oximetry on childhood pneumonia mortality in resource-poor settings. (2015) Floyd, Jessica; Wu, Lindsey; Hay Burgess, Deborah; Izadnegahdar, Rasa; Mukanga, David; Ghani, Azra C

Reply to "Drug Susceptibility of Genetically Engineered Trypanosoma cruzi Strains and Sterile Cure in Animal Models as a Criterion for Potential Clinical Efficacy of Anti-T. cruzi Drugs". (2015) Francisco, Amanda Fortes; Lewis, Michael D; Jayawardhana, Shiromani; Taylor, Martin C; Chatelain, Eric; Kelly, John M

Salmonella Infections in The Gambia, 2005-2015. (2015) Kwambana-Adams, Brenda; Darboe, Saffiatou; Nabwera, Helen; Foster-Nyarko, Ebenezer; Ikumapayi, Usman N; Secka, Ousman; Betts, Modupeh; Bradbury, Richard; Wegmüller, Rita; Lawal, Bolarinde; Saha, Debasish; Hossain, M Jahangir; Prentice, Andrew M; Kampmann, Beate; Anderson, Suzanne; Dalessandro, Umberto; Antonio, Martin

Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam. (2015) Le, Vien; Nhu, Nguyen Thi Khanh; Cerdeno-Tarraga, Ana; Campbell, James I; Tuyen, Ha Thanh; Nhu, Tran Do Hoang; Tam, Pham Thi Thanh; Schultsz, Constance; Thwaites, Guy; Thomson, Nicholas R; Baker, Stephen

Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease. (2015) Messenger, Louisa A; Miles, Michael A; Bern, Caryn

Molecular genotyping of Trypanosoma cruzi for lineage assignment and population genetics. (2015) Messenger, Louisa A; Yeo, Matthew; Lewis, Michael D; Llewellyn, Martin S; Miles, Michael A

Antimicrobial Drug Resistance of Vibrio cholerae, Democratic Republic of the Congo. (2015) Miwanda, Berthe; Moore, Sandra; Muyembe, Jean-Jacques; Nguefack-Tsague, Georges; Kabangwa, Ickel Kakongo; Ndjakani, Daniel Yassa; Mutreja, Ankur; Thomson, Nicholas; Thefenne, Helene; Garnotel, Eric; Tshapenda, Gaston; Kakongo, Denis Kandolo; Kalambayi, Guy; Piarroux, Renaud

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. (2015) Phillips, Margaret A; Lotharius, Julie; Marsh, Kennan; White, John; Dayan, Anthony; White, Karen L; Njoroge, Jacqueline W; El Mazouni, Farah; Lao, Yanbin; Kokkonda, Sreekanth; Tomchick, Diana R; Deng, Xiaoyi; Laird, Trevor; Bhatia, Sangeeta N; March, Sandra; Ng, Caroline L; Fidock, David A; Wittlin, Sergio; Lafuente-Monasterio, Maria; Benito, Francisco Javier Gamo; Alonso, Laura Maria Sanz; Martinez, Maria Santos; Jimenez-Diaz, Maria Belen; Bazaga, Santiago Ferrer; Angulo-Barturen, Iñigo; Haselden, John N; Louttit, James; Cui, Yi; Sridhar, Arun; Zeeman, Anna-Marie; Kocken, Clemens; Sauerwein, Robert; Dechering, Koen; Avery, Vicky M; Duffy, Sandra; Delves, Michael; Sinden, Robert; Ruecker, Andrea; Wickham, Kristina S; Rochford, Rosemary; Gahagen, Janet; Iyer, Lalitha; Riccio, Ed; Mirsalis, Jon; Bathhurst, Ian; Rueckle, Thomas; Ding, Xavier; Campo, Brice; Leroy, Didier; Rogers, M John; Rathod, Pradipsinh K; Burrows, Jeremy N; Charman, Susan A

Estimating malaria transmission from humans to mosquitoes in a noisy landscape. (2015) Reiner, Robert C; Guerra, Carlos; Donnelly, Martin J; Bousema, Teun; Drakeley, Chris; Smith, David L

Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus. (2015) Ronacher, Katharina; Joosten, Simone A; van Crevel, Reinout; Dockrell, Hazel M; Walzl, Gerhard; Ottenhoff, Tom HM

Perspectives on Advances in Tuberculosis Diagnostics, Drugs, and Vaccines. (2015) Schito, Marco; Migliori, Giovanni Battista; Fletcher, Helen A; McNerney, Ruth; Centis, Rosella; D'Ambrosio, Lia; Bates, Matthew; Kibiki, Gibson; Kapata, Nathan; Corrah, Tumena; Bomanji, Jamshed; Vilaplana, Cris; Johnson, Daniel; Mwaba, Peter; Maeurer, Markus; Zumla, Alimuddin

Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies. (2015) Slater, Hannah C; Ross, Amanda; Ouédraogo, André Lin; White, Lisa J; Nguon, Chea; Walker, Patrick GT; Ngor, Pengby; Aguas, Ricardo; Silal, Sheetal P; Dondorp, Arjen M; La Barre, Paul; Burton, Robert; Sauerwein, Robert W; Drakeley, Chris; Smith, Thomas A; Bousema, Teun; Ghani, Azra C

The Standard Membrane Feeding Assay: Advances Using Bioluminescence. (2015) Stone, Will JR; Bousema, Teun

Comparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies. (2015) Wu, Lindsey; van den Hoogen, Lotus L; Slater, Hannah; Walker, Patrick GT; Ghani, Azra C; Drakeley, Chris J; Okell, Lucy C