Items where Faculty or Department is "Department of Infection Biology"

LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Immunology and Infection (-2019) (972)

Dept of Pathogen Molecular Biology (-2019) (1192) Month Authors/Creators Item Type Full Text

December 2014

Association of antenatal depression with adverse consequences for the mother and newborn in rural Ghana: findings from the DON population-based cohort study. (2014) Weobong, Benedict; ten Asbroek, Augustinus HA; Soremekun, Seyi; Manu, Alexander A; Owusu-Agyei, Seth; Prince, Martin; Kirkwood, Betty R

The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, Kenya. (2014) Ochola-Oyier, Lynette Isabella; Okombo, John; Mwai, Leah; Kiara, Steven M; Pole, Lewa; Tetteh, Kevin KA; Nzila, Alexis; Marsh, Kevin

Prevalence of Type VI Secretion System in Spanish Campylobacter jejuni Isolates. (2014) Ugarte-Ruiz, M; Stabler, RA; Domínguez, L; Porrero, MC; Wren, BW; Dorrell, N; Gundogdu, O

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes. (2014) Glover, Lucy; Alsford, Sam; Baker, Nicola; Turner, Daniel J; Sanchez-Flores, Alejandro; Hutchinson, Sebastian; Hertz-Fowler, Christiane; Berriman, Matthew; Horn, David

Efficacy of indoor residual spraying with dichlorodiphenyltrichloroethane against malaria in Gambian communities with high usage of long-lasting insecticidal mosquito nets: a cluster-randomised controlled trial. (2014) Pinder, Margaret; Jawara, Musa; Jarju, Lamin BS; Salami, Kolawole; Jeffries, David; Adiamoh, Majidah; Bojang, Kalifa; Correa, Simon; Kandeh, Balla; Kaur, Harparkash; Conway, David J; D'Alessandro, Umberto; Lindsay, Steve W

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria. (2014) White, Nicholas J; Ashley, Elizabeth A; Recht, Judith; Delves, Michael J; Ruecker, Andrea; Smithuis, Frank M; Eziefula, Alice C; Bousema, Teun; Drakeley, Chris; Chotivanich, Kesinee; Imwong, Mallika; Pukrittayakamee, Sasithon; Prachumsri, Jetsumon; Chu, Cindy; Andolina, Chiara; Bancone, Germana; Hien, Tran T; Mayxay, Mayfong; Taylor, Walter RJ; von Seidlein, Lorenz; Price, Ric N; Barnes, Karen I; Djimdé, Abdoulaye; ter Kuile, Feiko; Gosling, Roly; Chen, Ingrid; Dhorda, Mehul J; Stepniewska, Kasia; Guérin, Philippe; Woodrow, Charles J; Dondorp, Arjen M; Day, Nicholas PJ; Nosten, Francois H

Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains. (2014) Chugh, Monika; Scheurer, Christian; Sax, Sibylle; Bilsland, Elizabeth; van Schalkwyk, Donelly A; Wicht, Kathryn J; Hofmann, Natalie; Sharma, Anil; Bashyam, Sridevi; Singh, Shivendra; Oliver, Stephen G; Egan, Timothy J; Malhotra, Pawan; Sutherland, Colin J; Beck, Hans-Peter; Wittlin, Sergio; Spangenberg, Thomas; Ding, Xavier C

Plasmodium alveolins possess distinct but structurally and functionally related multi-repeat domains. (2014) Al-Khattaf, Fatimah S; Tremp, Annie Z; Dessens, Johannes T

A proportion of mutations fixed in the genomes of in vitro selected isogenic drug-resistant Mycobacterium tuberculosis mutants can be detected as minority variants in the parent culture. (2014) Bergval, Indra; Coll, Francesc; Schuitema, Anja; de Ronde, Hans; Mallard, Kim; Pain, Arnab; McNerney, Ruth; Clark, Taane G; Anthony, Richard M

Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A. (2014) Tanner, Rachel; Kakalacheva, Kristina; Miller, Ellen; Pathan, Ansar A; Chalk, Rod; Sander, Clare R; Scriba, Tom; Tameris, Michelle; Hawkridge, Tony; Mahomed, Hassan; Hussey, Greg; Hanekom, Willem; Checkley, Anna; McShane, Helen; Fletcher, Helen A

Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development. (2014) Lamour, Sabrina D; Straschil, Ursula; Saric, Jasmina; Delves, Michael J

Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya. (2014) Okombo, John; Kamau, Alice W; Marsh, Kevin; Sutherland, Colin J; Ochola-Oyier, Lynette Isabella

November 2014

The Plasmodium berghei sexual stage antigen PSOP12 induces anti-malarial transmission blocking immunity both in vivo and in vitro. (2014) Sala, KA; Nishiura, H; Upton, LM; Zakutansky, SE; Delves, MJ; Iyori, M; Mizutani, M; Sinden, RE; Yoshida, S; Blagborough, AM

Genetic diversity of Mycobacterium tuberculosis isolated from tuberculosis patients in the Serengeti ecosystem in Tanzania. (2014) Mbugi, Erasto V; Katale, Bugwesa Z; Siame, Keith K; Keyyu, Julius D; Kendall, Sharon L; Dockrell, Hazel M; Streicher, Elizabeth M; Michel, Anita L; Rweyemamu, Mark M; Warren, Robin M; Matee, Mecky I; van Helden, Paul D

A complete view of the genetic diversity of the Escherichia coli O-antigen biosynthesis gene cluster. (2014) Iguchi, Atsushi; Iyoda, Sunao; Kikuchi, Taisei; Ogura, Yoshitoshi; Katsura, Keisuke; Ohnishi, Makoto; Hayashi, Tetsuya; Thomson, Nicholas R

Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus. (2014) Sung, Po-Yu; Roy, Polly

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum. (2014) Vaidya, Akhil B; Morrisey, Joanne M; Zhang, Zhongsheng; Das, Sudipta; Daly, Thomas M; Otto, Thomas D; Spillman, Natalie J; Wyvratt, Matthew; Siegl, Peter; Marfurt, Jutta; Wirjanata, Grennady; Sebayang, Boni F; Price, Ric N; Chatterjee, Arnab; Nagle, Advait; Stasiak, Marcin; Charman, Susan A; Angulo-Barturen, Iñigo; Ferrer, Santiago; Belén Jiménez-Díaz, María; Martínez, María Santos; Gamo, Francisco Javier; Avery, Vicky M; Ruecker, Andrea; Delves, Michael; Kirk, Kiaran; Berriman, Matthew; Kortagere, Sandhya; Burrows, Jeremy; Fan, Erkang; Bergman, Lawrence W

Serologically defined variations in malaria endemicity in Pará state, Brazil. (2014) Cunha, Maristela G; Silva, Eliane S; Sepúlveda, Nuno; Costa, Sheyla PT; Saboia, Tiago C; Guerreiro, João F; Póvoa, Marinete M; Corran, Patrick H; Riley, Eleanor; Drakeley, Chris J

Metabolic, immune, and gut microbial signals mount a systems response to Leishmania major infection. (2014) Lamour, Sabrina D; Veselkov, Kirill A; Posma, Joram M; Giraud, Emilie; Rogers, Matthew E; Croft, Simon; Marchesi, Julian R; Holmes, Elaine; Seifert, Karin; Saric, Jasmina

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans. (2014) Malmquist, Nicholas A; Sundriyal, Sandeep; Caron, Joachim; Chen, Patty; Witkowski, Benoit; Menard, Didier; Suwanarusk, Rossarin; Renia, Laurent; Nosten, Francois; Jiménez-Díaz, María Belén; Angulo-Barturen, Iñigo; Santos Martínez, María; Ferrer, Santiago; Sanz, Laura M; Gamo, Francisco-Javier; Wittlin, Sergio; Duffy, Sandra; Avery, Vicky M; Ruecker, Andrea; Delves, Michael J; Sinden, Robert E; Fuchter, Matthew J; Scherf, Artur

Serological markers for monitoring historical changes in malaria transmission intensity in a highly endemic region of Western Kenya, 1994-2009. (2014) Wong, Jacklyn; Hamel, Mary J; Drakeley, Chris J; Kariuki, Simon; Shi, Ya Ping; Lal, Altaf A; Nahlen, Bernard L; Bloland, Peter B; Lindblade, Kim A; Were, Vincent; Otieno, Kephas; Otieno, Peter; Odero, Chris; Slutsker, Laurence; Vulule, John M; Gimnig, John E

SRST2: Rapid genomic surveillance for public health and hospital microbiology labs. (2014) Inouye, Michael; Dashnow, Harriet; Raven, Lesley-Ann; Schultz, Mark B; Pope, Bernard J; Tomita, Takehiro; Zobel, Justin; Holt, Kathryn E

Galleria mellonella is an effective model to study Actinobacillus pleuropneumoniae infection. (2014) Pereira, Monalessa Fábia; Rossi, Ciro César; Vieira de Queiroz, Marisa; Martins, Gustavo Ferreira; Isaac, Clement; Bossé, Janine T; Li, Yanwen; Wren, Brendan W; Terra, Vanessa Sofia; Cuccui, Jon; Langford, Paul R; Bazzolli, Denise Mara Soares

The generation of successive unmarked mutations and chromosomal insertion of heterologous genes in Actinobacillus pleuropneumoniae using natural transformation. (2014) Bossé, Janine T; Soares-Bazzolli, Denise M; Li, Yanwen; Wren, Brendan W; Tucker, Alexander W; Maskell, Duncan J; Rycroft, Andrew N; Langford, Paul R; BRaDP1T Consortium

Efficacy and safety of the mosquitocidal drug ivermectin to prevent malaria transmission after treatment: a double-blind, randomized, clinical trial. (2014) Ouédraogo, André Lin; Bastiaens, Guido JH; Tiono, Alfred B; Guelbéogo, Wamdaogo M; Kobylinski, Kevin C; Ouédraogo, Alphonse; Barry, Aïssata; Bougouma, Edith C; Nebie, Issa; Ouattara, Maurice San; Lanke, Kjerstin HW; Fleckenstein, Lawrence; Sauerwein, Robert W; Slater, Hannah C; Churcher, Thomas S; Sirima, Sodiomon B; Drakeley, Chris; Bousema, Teun

Species diversity of non-tuberculous mycobacteria isolated from humans, livestock and wildlife in the Serengeti ecosystem, Tanzania. (2014) Katale, Bugwesa Z; Mbugi, Erasto V; Botha, Louise; Keyyu, Julius D; Kendall, Sharon; Dockrell, Hazel M; Michel, Anita L; Kazwala, Rudovick R; Rweyemamu, Mark M; van Helden, Paul; Matee, Mecky I ['material/summary:fileicon_text/html' not defined]

Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting. (2014) Perdigão, João; Silva, Hugo; Machado, Diana; Macedo, Rita; Maltez, Fernando; Silva, Carla; Jordao, Luisa; Couto, Isabel; Mallard, Kim; Coll, Francesc; Hill-Cawthorne, Grant A; McNerney, Ruth; Pain, Arnab; Clark, Taane G; Viveiros, Miguel; Portugal, Isabel

CD4+ T cell epitopes of FliC conserved between strains of Burkholderia: implications for vaccines against melioidosis and cepacia complex in cystic fibrosis. (2014) Musson, Julie A; Reynolds, Catherine J; Rinchai, Darawan; Nithichanon, Arnone; Khaenam, Prasong; Favry, Emmanuel; Spink, Natasha; Chu, Karen KY; De Soyza, Anthony; Bancroft, Gregory J; Lertmemongkolchai, Ganjana; Maillere, Bernard; Boyton, Rosemary J; Altmann, Daniel M; Robinson, John H

Nitroimidazo-oxazole compound DNDI-VL-2098: an orally effective preclinical drug candidate for the treatment of visceral leishmaniasis. (2014) Gupta, Suman; Yardley, Vanessa; Vishwakarma, Preeti; Shivahare, Rahul; Sharma, Bhawna; Launay, Delphine; Martin, Denis; Puri, Sunil K

Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations. (2014) Upton, LM; Brock, PM; Churcher, TS; Ghani, AC; Gething, PW; Delves, MJ; Sala, KA; Leroy, D; Sinden, RE; Blagborough, AM

The extant World War 1 dysentery bacillus NCTC1: a genomic analysis. (2014) Baker, Kate S; Mather, Alison E; McGregor, Hannah; Coupland, Paul; Langridge, Gemma C; Day, Martin; Deheer-Graham, Ana; Parkhill, Julian; Russell, Julie E; Thomson, Nicholas R

Bacillary dysentery from World War 1 and NCTC1, the first bacterial isolate in the National Collection. (2014) Mather, Alison E; Baker, Kate S; McGregor, Hannah; Coupland, Paul; Mather, Pamela L; Deheer-Graham, Ana; Parkhill, Julian; Bracegirdle, Philippa; Russell, Julie E; Thomson, Nicholas R

Gene expression and cytokine profile correlate with mycobacterial growth in a human BCG challenge model. (2014) Matsumiya, Magali; Satti, Iman; Chomka, Agnieszka; Harris, Stephanie A; Stockdale, Lisa; Meyer, Joel; Fletcher, Helen A; McShane, Helen

Impact of co-infections and BCG immunisation on immune responses among household contacts of tuberculosis patients in a Ugandan cohort. (2014) Biraro, Irene A; Egesa, Moses; Toulza, Frederic; Levin, Jonathan; Cose, Stephen; Joloba, Moses; Smith, Steven; Dockrell, Hazel M; Katamba, Achilles; Elliott, Alison M

Detection of single-nucleotide polymorphisms in Plasmodium falciparum by PCR primer extension and lateral flow immunoassay. (2014) Moers, APHA; Hallett, RL; Burrow, R; Schallig, HDFH; Sutherland, CJ; van Amerongen, A

Multiple roles of the cytoskeleton in bacterial autophagy. (2014) Mostowy, Serge

October 2014

CATH: comprehensive structural and functional annotations for genome sequences. (2014) Sillitoe, Ian; Lewis, Tony E; Cuff, Alison; Das, Sayoni; Ashford, Paul; Dawson, Natalie L; Furnham, Nicholas; Laskowski, Roman A; Lee, David; Lees, Jonathan G; Lehtinen, Sonja; Studer, Romain A; Thornton, Janet; Orengo, Christine A

Protein energy malnutrition increases arginase activity in monocytes and macrophages. (2014) Corware, Karina; Yardley, Vanessa; Mack, Christopher; Schuster, Steffen; Al-Hassi, Hafid; Herath, Shanthi; Bergin, Philip; Modolell, Manuel; Munder, Markus; Müller, Ingrid; Kropf, Pascale

IgG1 as a potential biomarker of post-chemotherapeutic relapse in visceral leishmaniasis, and adaptation to a rapid diagnostic test. (2014) Bhattacharyya, Tapan; Ayandeh, Armon; Falconar, Andrew K; Sundar, Shyam; El-Safi, Sayda; Gripenberg, Marissa A; Bowes, Duncan E; Thunissen, Caroline; Singh, Om Prakash; Kumar, Rajiv; Ahmed, Osman; Eisa, Osama; Saad, Alfarazdeg; Silva Pereira, Sara; Boelaert, Marleen; Mertens, Pascal; Miles, Michael A

Mapping infectious disease landscapes: unmanned aerial vehicles and epidemiology. (2014) Fornace, Kimberly M; Drakeley, Chris J; William, Timothy; Espino, Fe; Cox, Jonathan

School-based countrywide seroprevalence survey reveals spatial heterogeneity in malaria transmission in the Gambia. (2014) Okebe, Joseph; Affara, Muna; Correa, Simon; Muhammad, Abdul Khalie; Nwakanma, Davis; Drakeley, Chris; D'Alessandro, Umberto

Recurrence due to relapse or reinfection with Mycobacterium tuberculosis: a whole-genome sequencing approach in a large, population-based cohort with a high HIV infection prevalence and active follow-up. (2014) Guerra-Assunção, José Afonso; Houben, Rein MGJ; Crampin, Amelia C; Mzembe, Themba; Mallard, Kim; Coll, Francesc; Khan, Palwasha; Banda, Louis; Chiwaya, Arthur; Pereira, Rui PA; McNerney, Ruth; Harris, David; Parkhill, Julian; Clark, Taane G; Glynn, Judith R

Asymptomatic malaria infections: detectability, transmissibility and public health relevance. (2014) Bousema, Teun; Okell, Lucy; Felger, Ingrid; Drakeley, Chris

High levels of asymptomatic and subpatent Plasmodium falciparum parasite carriage at health facilities in an area of heterogeneous malaria transmission intensity in the Kenyan highlands. (2014) Stresman, Gillian H; Stevenson, Jennifer C; Ngwu, Nnenna; Marube, Elizabeth; Owaga, Chrispin; Drakeley, Chris; Bousema, Teun; Cox, Jonathan

Genome-wide evaluation of the interplay between Caenorhabditis elegans and Yersinia pseudotuberculosis during in vivo biofilm formation. (2014) Joshua, George WP; Atkinson, Steve; Goldstone, Robert J; Patrick, Hannah L; Stabler, Richard A; Purves, Joanne; Cámara, Miguel; Williams, Paul; Wren, Brendan W

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. (2014) Shameer, Sanu; Logan-Klumpler, Flora J; Vinson, Florence; Cottret, Ludovic; Merlet, Benjamin; Achcar, Fiona; Boshart, Michael; Berriman, Matthew; Breitling, Rainer; Bringaud, Frédéric; Bütikofer, Peter; Cattanach, Amy M; Bannerman-Chukualim, Bridget; Creek, Darren J; Crouch, Kathryn; de Koning, Harry P; Denise, Hubert; Ebikeme, Charles; Fairlamb, Alan H; Ferguson, Michael AJ; Ginger, Michael L; Hertz-Fowler, Christiane; Kerkhoven, Eduard J; Mäser, Pascal; Michels, Paul AM; Nayak, Archana; Nes, David W; Nolan, Derek P; Olsen, Christian; Silva-Franco, Fatima; Smith, Terry K; Taylor, Martin C; Tielens, Aloysius GM; Urbaniak, Michael D; van Hellemond, Jaap J; Vincent, Isabel M; Wilkinson, Shane R; Wyllie, Susan; Opperdoes, Fred R; Barrett, Michael P; Jourdan, Fabien

A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis. (2014) Burrell-Saward, Hollie; Rodgers, Jean; Bradley, Barbara; Croft, Simon L; Ward, Theresa H

A new experimental model for assessing drug efficacy against Trypanosoma cruzi infection based on highly sensitive in vivo imaging. (2014) Lewis, Michael D; Francisco, Amanda Fortes; Taylor, Martin C; Kelly, John M

Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines. (2014) Sola, Irene; Artigas, Albert; Taylor, Martin C; Gbedema, Stephen Y; Pérez, Belén; Clos, M Victòria; Wright, Colin W; Kelly, John M; Muñoz-Torrero, Diego

Modeling the cost effectiveness of malaria control interventions in the highlands of western Kenya. (2014) Stuckey, Erin M; Stevenson, Jennifer; Galactionova, Katya; Baidjoe, Amrish Y; Bousema, Teun; Odongo, Wycliffe; Kariuki, Simon; Drakeley, Chris; Smith, Thomas A; Cox, Jonathan; Chitnis, Nakul

Global and local genetic diversity at two microsatellite loci in Plasmodium vivax parasites from Asia, Africa and South America. (2014) Schousboe, Mette L; Ranjitkar, Samir; Rajakaruna, Rupika S; Amerasinghe, Priyanie H; Konradsen, Flemming; Morales, Francisco; Ord, Rosalynn; Pearce, Richard; Leslie, Toby; Rowland, Mark; Gadalla, Nahla; Bygbjerg, Ib C; Alifrangis, Michael; Roper, Cally ['material/summary:fileicon_text/html' not defined]

Robust identification of noncoding RNA from transcriptomes requires phylogenetically-informed sampling. (2014) Lindgreen, Stinus; Umu, Sinan Uğur; Lai, Alicia Sook-Wei; Eldai, Hisham; Liu, Wenting; McGimpsey, Stephanie; Wheeler, Nicole E; Biggs, Patrick J; Thomson, Nick R; Barquist, Lars; Poole, Anthony M; Gardner, Paul P

September 2014

Pathogenicity study in sheep using reverse-genetics-based reassortant bluetongue viruses. (2014) Celma, Cristina C; Bhattacharya, Bishnupriya; Eschbaumer, Michael; Wernike, Kerstin; Beer, Martin; Roy, Polly

A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs. (2014) Ruecker, A; Mathias, DK; Straschil, U; Churcher, TS; Dinglasan, RR; Leroy, D; Sinden, RE; Delves, MJ

Efficacy and safety of triple combination therapy with artesunate-amodiaquine-methylene blue for falciparum malaria in children: a randomized controlled trial in Burkina Faso. (2014) Coulibaly, Boubacar; Pritsch, Michael; Bountogo, Mamadou; Meissner, Peter E; Nebié, Eric; Klose, Christina; Kieser, Meinhard; Berens-Riha, Nicole; Wieser, Andreas; Sirima, Sodiomon B; Breitkreutz, Jörg; Schirmer, R Heiner; Sié, Ali; Mockenhaupt, Frank P; Drakeley, Chris; Bousema, Teun; Müller, Olaf

Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients. (2014) Gadalla, Nahla B; Malmberg, Maja; Adam, Ishag; Oguike, Mary C; Beshir, Khalid; Elzaki, Salah-Eldin; Mukhtar, Izdihar; Gadalla, Amal A; Warhurst, David C; Ngasala, Billy; Mårtensson, Andreas; El-Sayed, Badria B; Gil, J Pedro; Sutherland, Colin J

An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission. (2014) Marques, Sara R; Ramakrishnan, Chandra; Carzaniga, Raffaella; Blagborough, Andrew M; Delves, Michael J; Talman, Arthur M; Sinden, Robert E

Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy. (2014) Walker, Michael L; Holt, Kathryn E; Anderson, Gary P; Teo, Shu Mei; Sly, Peter D; Holt, Patrick G; Inouye, Michael

Hijacking bacterial glycosylation for the production of glycoconjugates, from vaccines to humanised glycoproteins. (2014) Cuccui, Jon; Wren, Brendan

Focal screening and treatment for malaria: defining the sentinel population. (2014) Stresman, Gillian H; Baidjoe, Amrish; Stevenson, Jennifer; Odongo, Wycliffe; Owaga, Chrispin; Marube, Elizabeth; Osoti, Victor; Makori, Euniah; Shagari, Shehu; Drakeley, Chris; Cox, Jonathan; Bousema, Teun

The importance of the magnesium transporter MgtB for virulence of Yersinia pseudotuberculosis and Yersinia pestis. (2014) Ford, Donna C; Joshua, George WP; Wren, Brendan W; Oyston, Petra CF

The post-translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence. (2014) Faulds-Pain, Alexandra; Twine, Susan M; Vinogradov, Evgeny; Strong, Philippa CR; Dell, Anne; Buckley, Anthony M; Douce, Gillian R; Valiente, Esmeralda; Logan, Susan M; Wren, Brendan W

Host immunity to Clostridium difficile PCR ribotype 017 strains. (2014) Jafari, Nazila V; Songane, Mario; Stabler, Richard A; Elawad, Mamoun; Wren, Brendan W; Allan, Elaine; Bajaj-Elliott, Mona

Use of Shigella flexneri to study autophagy-cytoskeleton interactions. (2014) Mazon Moya, Maria J; Colucci-Guyon, Emma; Mostowy, Serge

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts. (2014) Otto, Thomas D; Rayner, Julian C; Böhme, Ulrike; Pain, Arnab; Spottiswoode, Natasha; Sanders, Mandy; Quail, Michael; Ollomo, Benjamin; Renaud, François; Thomas, Alan W; Prugnolle, Franck; Conway, David J; Newbold, Chris; Berriman, Matthew

Circulating B-lymphocytes as potential biomarkers of tuberculosis infection activity. (2014) Sebina, Ismail; Biraro, Irene A; Dockrell, Hazel M; Elliott, Alison M; Cose, Stephen

Distinct temporal recruitment of Plasmodium alveolins to the subpellicular network. (2014) Tremp, Annie Z; Al-Khattaf, Fatimah S; Dessens, Johannes T

Functional and bioinformatics analysis of two Campylobacter jejuni homologs of the thiol-disulfide oxidoreductase, DsbA. (2014) Grabowska, Anna D; Wywiał, Ewa; Dunin-Horkawicz, Stanislaw; Łasica, Anna M; Wösten, Marc MSM; Nagy-Staroń, Anna; Godlewska, Renata; Bocian-Ostrzycka, Katarzyna; Pieńkowska, Katarzyna; Łaniewski, Paweł; Bujnicki, Janusz M; van Putten, Jos PM; Jagusztyn-Krynicka, E Katarzyna

A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. (2014) Coll, Francesc; McNerney, Ruth; Guerra-Assunção, José Afonso; Glynn, Judith R; Perdigão, João; Viveiros, Miguel; Portugal, Isabel; Pain, Arnab; Martin, Nigel; Clark, Taane G

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. (2014) Takala-Harrison, Shannon; Jacob, Christopher G; Arze, Cesar; Cummings, Michael P; Silva, Joana C; Dondorp, Arjen M; Fukuda, Mark M; Hien, Tran Tinh; Mayxay, Mayfong; Noedl, Harald; Nosten, Francois; Kyaw, Myat P; Nhien, Nguyen Thanh Thuy; Imwong, Mallika; Bethell, Delia; Se, Youry; Lon, Chanthap; Tyner, Stuart D; Saunders, David L; Ariey, Frederic; Mercereau-Puijalon, Odile; Menard, Didier; Newton, Paul N; Khanthavong, Maniphone; Hongvanthong, Bouasy; Starzengruber, Peter; Fuehrer, Hans-Peter; Swoboda, Paul; Khan, Wasif A; Phyo, Aung Pyae; Nyunt, Myaing M; Nyunt, Myat H; Brown, Tyler S; Adams, Matthew; Pepin, Christopher S; Bailey, Jason; Tan, John C; Ferdig, Michael T; Clark, Taane G; Miotto, Olivo; MacInnis, Bronwyn; Kwiatkowski, Dominic P; White, Nicholas J; Ringwald, Pascal; Plowe, Christopher V

August 2014

Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors. (2014) Donahue, Elizabeth H; Dawson, Lisa F; Valiente, Esmeralda; Firth-Clark, Stuart; Major, Meriel R; Littler, Eddy; Perrior, Trevor R; Wren, Brendan W

Optimized multilocus sequence typing (MLST) scheme for Trypanosoma cruzi. (2014) Diosque, Patricio; Tomasini, Nicolás; Lauthier, Juan José; Messenger, Louisa Alexandra; Monje Rumi, María Mercedes; Ragone, Paula Gabriela; Alberti-D'Amato, Anahí Maitén; Pérez Brandán, Cecilia; Barnabé, Christian; Tibayrenc, Michel; Lewis, Michael David; Llewellyn, Martin Stephen; Miles, Michael Alexander; Yeo, Matthew

Comparative assessment of diverse strategies for malaria vector population control based on measured rates at which mosquitoes utilize targeted resource subsets. (2014) Killeen, Gerry F; Kiware, Samson S; Seyoum, Aklilu; Gimnig, John E; Corliss, George F; Stevenson, Jennifer; Drakeley, Christopher J; Chitnis, Nakul

Factors that are associated with the risk of acquiring Plasmodium knowlesi malaria in Sabah, Malaysia: a case-control study protocol. (2014) Grigg, MJ; William, T; Drakeley, CJ; Jelip, J; von Seidlein, L; Barber, BE; Fornace, KM; Anstey, NM; Yeo, TW; Cox, J

Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity. (2014) Zingales, Bianca; Miles, Michael A; Moraes, Carolina B; Luquetti, Alejandro; Guhl, Felipe; Schijman, Alejandro G; Ribeiro, Isabela; Drugs for Neglected Disease Initiative; Chagas Clinical Research Platform Meeting

Bluetongue virus capsid assembly and maturation. (2014) Mohl, Bjorn-Patrick; Roy, Polly

Trafficking of bluetongue virus visualized by recovery of tetracysteine-tagged virion particles. (2014) Du, Junzheng; Bhattacharya, Bishnupriya; Ward, Theresa H; Roy, Polly

Prominent intraspecific genetic divergence within Anopheles gambiae sibling species triggered by habitat discontinuities across a riverine landscape. (2014) Caputo, B; Nwakanma, D; Caputo, FP; Jawara, M; Oriero, EC; Hamid-Adiamoh, M; Dia, I; Konate, L; Petrarca, V; Pinto, J; Conway, DJ; Della Torre, A

Structure based modification of Bluetongue virus helicase protein VP6 to produce a viable VP6-truncated BTV. (2014) Matsuo, Eiko; Leon, Esther; Matthews, Steve J; Roy, Polly

A conserved domain targets exported PHISTb family proteins to the periphery of Plasmodium infected erythrocytes. (2014) Tarr, Sarah J; Moon, Robert W; Hardege, Iris; Osborne, Andrew R

Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1. (2014) Kher, Samir S; Penzo, Maria; Fulle, Simone; Finn, Paul W; Blackman, Michael J; Jirgensons, Aigars description

July 2014

Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1. (2014) Ansell, Keith H; Jones, Hayley M; Whalley, David; Hearn, Alisdair; Taylor, Debra L; Patin, Emmanuel C; Chapman, Timothy M; Osborne, Simon A; Wallace, Claire; Birchall, Kristian; Large, Jonathan; Bouloc, Nathalie; Smiljanic-Hurley, Ela; Clough, Barbara; Moon, Robert W; Green, Judith L; Holder, Anthony A

Transmission and control of Plasmodium knowlesi: a mathematical modelling study. (2014) Imai, Natsuko; White, Michael T; Ghani, Azra C; Drakeley, Chris J

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. (2014) Venkatesan, Meera; Gadalla, Nahla B; Stepniewska, Kasia; Dahal, Prabin; Nsanzabana, Christian; Moriera, Clarissa; Price, Ric N; Mårtensson, Andreas; Rosenthal, Philip J; Dorsey, Grant; Sutherland, Colin J; Guérin, Philippe; Davis, Timothy ME; Ménard, Didier; Adam, Ishag; Ademowo, George; Arze, Cesar; Baliraine, Frederick N; Berens-Riha, Nicole; Björkman, Anders; Borrmann, Steffen; Checchi, Francesco; Desai, Meghna; Dhorda, Mehul; Djimdé, Abdoulaye A; El-Sayed, Badria B; Eshetu, Teferi; Eyase, Frederick; Falade, Catherine; Faucher, Jean-François; Fröberg, Gabrielle; Grivoyannis, Anastasia; Hamour, Sally; Houzé, Sandrine; Johnson, Jacob; Kamugisha, Erasmus; Kariuki, Simon; Kiechel, Jean-René; Kironde, Fred; Kofoed, Poul-Erik; LeBras, Jacques; Malmberg, Maja; Mwai, Leah; Ngasala, Billy; Nosten, Francois; Nsobya, Samuel L; Nzila, Alexis; Oguike, Mary; Otienoburu, Sabina Dahlström; Ogutu, Bernhards; Ouédraogo, Jean-Bosco; Piola, Patrice; Rombo, Lars; Schramm, Birgit; Somé, A Fabrice; Thwing, Julie; Ursing, Johan; Wong, Rina PM; Zeynudin, Ahmed; Zongo, Issaka; Plowe, Christopher V; Sibley, Carol Hopkins; Asaq Molecular Marker Study Group

Immunogenicity of recombinant VP2 proteins of all nine serotypes of African horse sickness virus. (2014) Kanai, Yuta; van Rijn, Piet A; Maris-Veldhuis, Mieke; Kaname, Yuki; Athmaram, TN; Roy, Polly

Magnetic resonance imaging during life: the key to unlock cerebral malaria pathogenesis? (2014) Mohanty, Sanjib; Taylor, Terrie E; Kampondeni, Sam; Potchen, Mike J; Panda, Premanand; Majhi, Megharay; Mishra, Saroj K; Wassmer, Samuel C

The association between the ratio of monocytes:lymphocytes at age 3 months and risk of tuberculosis (TB) in the first two years of life. (2014) Naranbhai, Vivek; Kim, Soyeon; Fletcher, Helen; Cotton, Mark F; Violari, Avy; Mitchell, Charles; Nachman, Sharon; McSherry, George; McShane, Helen; Hill, Adrian VS; Madhi, Shabir A

Quantifying travel behavior for infectious disease research: a comparison of data from surveys and mobile phones. (2014) Wesolowski, Amy; Stresman, Gillian; Eagle, Nathan; Stevenson, Jennifer; Owaga, Chrispin; Marube, Elizabeth; Bousema, Teun; Drakeley, Christopher; Cox, Jonathan; Buckee, Caroline O

Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali. (2014) Maiga, Bakary; Dolo, Amagana; Campino, Susana; Sepulveda, Nuno; Corran, Patrick; Rockett, Kirk A; Troye-Blomberg, Marita; Doumbo, Ogobara K; Clark, Taane G

Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania. (2014) Kavishe, Reginald A; Paulo, Petro; Kaaya, Robert D; Kalinga, Akili; van Zwetselaar, Marco; Chilongola, Jaffu; Roper, Cally; Alifrangis, Michael

Genetic diversity and population structure of Plasmodium vivax in Central China. (2014) Liu, Yaobao; Auburn, Sarah; Cao, Jun; Trimarsanto, Hidayat; Zhou, Huayun; Gray, Karen-Ann; Clark, Taane G; Price, Ric N; Cheng, Qin; Huang, Rui; Gao, Qi

Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes. (2014) Miura, Kazutoyo; Jongert, Erik; Deng, Bingbing; Zhou, Luwen; Lusingu, John P; Drakeley, Chris J; Fay, Michael P; Long, Carole A; Vekemans, Johan

The evolution of enzyme function in the isomerases. (2014) Martinez Cuesta, Sergio; Furnham, Nicholas; Rahman, Syed Asad; Sillitoe, Ian; Thornton, Janet M

Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT. (2014) Henriques, Gisela; Hallett, Rachel L; Beshir, Khalid B; Gadalla, Nahla B; Johnson, Rachel E; Burrow, Rebekah; van Schalkwyk, Donelly A; Sawa, Patrick; Omar, Sabah A; Clark, Taane G; Bousema, Teun; Sutherland, Colin J

The population structure of Vibrio cholerae from the Chandigarh Region of Northern India. (2014) Abd El Ghany, Moataz; Chander, Jagadish; Mutreja, Ankur; Rashid, Mamoon; Hill-Cawthorne, Grant A; Ali, Shahjahan; Naeem, Raeece; Thomson, Nicholas R; Dougan, Gordon; Pain, Arnab

Multilocus sequence and microsatellite identification of intra-specific hybrids and ancestor-like donors among natural Ethiopian isolates of Leishmania donovani. (2014) Gelanew, Tesfaye; Hailu, Asrat; Schőnian, Gabriele; Lewis, Michael D; Miles, Michael A; Yeo, Matthew

On the performance of multiple imputation based on chained equations in tackling missing data of the African α3.7 -globin deletion in a malaria association study. (2014) Sepúlveda, Nuno; Manjurano, Alphaxard; Drakeley, Chris; Clark, Taane G

June 2014

Structural constraints in the packaging of bluetongue virus genomic segments. (2014) Burkhardt, Christiane; Sung, Po-Yu; Celma, Cristina C; Roy, Polly

Recombinations in staphylococcal cassette chromosome mec elements compromise the molecular detection of methicillin resistance in Staphylococcus aureus. (2014) Hill-Cawthorne, Grant A; Hudson, Lyndsey O; El Ghany, Moataz Fouad Abd; Piepenburg, Olaf; Nair, Mridul; Dodgson, Andrew; Forrest, Matthew S; Clark, Taane G; Pain, Arnab

Methods to measure potential spatial access to delivery care in low- and middle-income countries: a case study in rural Ghana. (2014) Nesbitt, Robin C; Gabrysch, Sabine; Laub, Alexandra; Soremekun, Seyi; Manu, Alexander; Kirkwood, Betty R; Amenga-Etego, Seeba; Wiru, Kenneth; Höfle, Bernhard; Grundy, Chris

Whole-genome scans provide evidence of adaptive evolution in Malawian Plasmodium falciparum isolates. (2014) Ocholla, Harold; Preston, Mark D; Mipando, Mwapatsa; Jensen, Anja TR; Campino, Susana; MacInnis, Bronwyn; Alcock, Daniel; Terlouw, Anja; Zongo, Issaka; Oudraogo, Jean-Bosco; Djimde, Abdoulaye A; Assefa, Samuel; Doumbo, Ogobara K; Borrmann, Steffen; Nzila, Alexis; Marsh, Kevin; Fairhurst, Rick M; Nosten, Francois; Anderson, Tim JC; Kwiatkowski, Dominic P; Craig, Alister; Clark, Taane G; Montgomery, Jacqui

TRANSVAC workshop on standardisation and harmonisation of analytical platforms for HIV, TB and malaria vaccines: 'how can big data help?'. (2014) Dutruel, Céline; Thole, Jelle; Geels, Mark; Mollenkopf, Hans-Joachim; Ottenhoff, Tom; Guzman, Carlos A; Fletcher, Helen A; Leroy, Odile; Kaufmann, Stefan HE

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. (2014) Preston, Mark D; Campino, Susana; Assefa, Samuel A; Echeverry, Diego F; Ocholla, Harold; Amambua-Ngwa, Alfred; Stewart, Lindsay B; Conway, David J; Borrmann, Steffen; Michon, Pascal; Zongo, Issaka; Ouédraogo, Jean-Bosco; Djimde, Abdoulaye A; Doumbo, Ogobara K; Nosten, Francois; Pain, Arnab; Bousema, Teun; Drakeley, Chris J; Fairhurst, Rick M; Sutherland, Colin J; Roper, Cally; Clark, Taane G

Killer-cell immunoglobulin-like receptors and falciparum malaria in southwest Nigeria. (2014) Olaniyan, Subulade A; Amodu, Olukemi K; Yindom, Louis-Marie; Conway, David J; Aka, Peter; Bakare, Adekunle A; Omotade, Olayemi O

Glucose-6-phosphate dehydrogenase status and risk of hemolysis in Plasmodium falciparum-infected African children receiving single-dose primaquine. (2014) Eziefula, Alice C; Pett, Helmi; Grignard, Lynn; Opus, Salome; Kiggundu, Moses; Kamya, Moses R; Yeung, Shunmay; Staedke, Sarah G; Bousema, Teun; Drakeley, Chris

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response. (2014) Matsumiya, Magali; Harris, Stephanie A; Satti, Iman; Stockdale, Lisa; Tanner, Rachel; O'Shea, Matthew K; Tameris, Michelle; Mahomed, Hassan; Hatherill, Mark; Scriba, Thomas J; Hanekom, Willem A; McShane, Helen; Fletcher, Helen A

RNA-seq analysis of the influence of anaerobiosis and FNR on Shigella flexneri. (2014) Vergara-Irigaray, Marta; Fookes, Maria C; Thomson, Nicholas R; Tang, Christoph M

Wild Trypanosoma cruzi I genetic diversity in Brazil suggests admixture and disturbance in parasite populations from the Atlantic Forest region. (2014) Lima, Valdirene S; Jansen, Ana M; Messenger, Louisa A; Miles, Michael A; Llewellyn, Martin S

Self-Assembly of Amyloid Fibrils That Display Active Enzymes. (2014) Zhou, Xiao-Ming; Entwistle, Aiman; Zhang, Hong; Jackson, Antony P; Mason, Thomas O; Shimanovich, Ulyana; Knowles, Tuomas PJ; Smith, Andrew T; Sawyer, Elizabeth B; Perrett, Sarah

May 2014

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial. (2014) Low, Jenny G; Sung, Cynthia; Wijaya, Limin; Wei, Yuan; Rathore, Abhay PS; Watanabe, Satoru; Tan, Boon Hian; Toh, Liying; Chua, Lian Tee; Hou, Yan'an; Chow, Angelia; Howe, Shiqin; Chan, Wing Ki; Tan, Kah Hin; Chung, Jasmine S; Cherng, Benjamin P; Lye, David C; Tambayah, Paul A; Ng, Lee Ching; Connolly, John; Hibberd, Martin L; Leo, Yee Sin; Cheung, Yin Bun; Ooi, Eng Eong; Vasudevan, Subhash G

Rational design of the first difluorostatone-based PfSUB1 inhibitors. (2014) Giovani, Simone; Penzo, Maria; Brogi, Simone; Brindisi, Margherita; Gemma, Sandra; Novellino, Ettore; Savini, Luisa; Blackman, Michael J; Campiani, Giuseppe; Butini, Stefania

Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition. (2014) Bhattacharyya, Tapan; Falconar, Andrew K; Luquetti, Alejandro O; Costales, Jaime A; Grijalva, Mario J; Lewis, Michael D; Messenger, Louisa A; Tran, Trang T; Ramirez, Juan-David; Guhl, Felipe; Carrasco, Hernan J; Diosque, Patricio; Garcia, Lineth; Litvinov, Sergey V; Miles, Michael A

Detection of persistent Plasmodium spp. infections in Ugandan children after artemether-lumefantrine treatment. (2014) Betson, Martha; Sousa-Figueiredo, José C; Atuhaire, Aaron; Arinaitwe, Moses; Adriko, Moses; Mwesigwa, Gerald; Nabonge, Juma; Kabatereine, Narcis B; Sutherland, Colin J; Stothard, J Russell

Cathepsin-L can resist lysis by human serum in Trypanosoma brucei brucei. (2014) Alsford, Sam; Currier, Rachel B; Guerra-Assunção, José Afonso; Clark, Taane G; Horn, David

Process of assay selection and optimization for the study of case and control samples from a phase IIb efficacy trial of a candidate tuberculosis vaccine, MVA85A. (2014) Harris, Stephanie A; Satti, Iman; Matsumiya, Magali; Stockdale, Lisa; Chomka, Agnieszka; Tanner, Rachel; O'Shea, Matthew K; Manjaly Thomas, Zita-Rose; Tameris, Michele; Mahomed, Hassan; Scriba, Thomas J; Hanekom, Willem A; Fletcher, Helen A; McShane, Helen

A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase. (2014) Stone, Will JR; Churcher, Thomas S; Graumans, Wouter; van Gemert, Geert-Jan; Vos, Martijn W; Lanke, Kjerstin HW; van de Vegte-Bolmer, Marga G; Siebelink-Stoter, Rianne; Dechering, Koen J; Vaughan, Ashley M; Camargo, Nelly; Kappe, Stefan HI; Sauerwein, Robert W; Bousema, Teun

Pseudaminic acid on Campylobacter jejuni flagella modulates dendritic cell IL-10 expression via Siglec-10 receptor: a novel flagellin-host interaction. (2014) Stephenson, Holly N; Mills, Dominic C; Jones, Hannah; Milioris, Enea; Copland, Alastair; Dorrell, Nick; Wren, Brendan W; Crocker, Paul R; Escors, David; Bajaj-Elliott, Mona

Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation. (2014) Karlyshev, AV; Thacker, G; Jones, MA; Clements, MO; Wren, BW

Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target. (2014) Tewari, Rita; Patzewitz, Eva-Maria; Poulin, Benoit; Stewart, Lindsay; Baker, David A

The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin. (2014) Withers-Martinez, Chrislaine; Strath, Malcolm; Hackett, Fiona; Haire, Lesley F; Howell, Steven A; Walker, Philip A; Christodoulou, Evangelos; Dodson, Guy G; Blackman, Michael J

Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection. (2014) Lewis, Michael D; Fortes Francisco, Amanda; Taylor, Martin C; Burrell-Saward, Hollie; McLatchie, Alex P; Miles, Michael A; Kelly, John M

Validation of three geolocation strategies for health-facility attendees for research and public health surveillance in a rural setting in western Kenya. (2014) Stresman, GH; Stevenson, JC; Owaga, C; Marube, E; Anyango, C; Drakeley, C; Bousema, T; Cox, J

An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution. (2014) Waddington, Claire S; Darton, Thomas C; Jones, Claire; Haworth, Kathryn; Peters, Anna; John, Tessa; Thompson, Ben AV; Kerridge, Simon A; Kingsley, Robert A; Zhou, Liqing; Holt, Kathryn E; Yu, Ly-Mee; Lockhart, Stephen; Farrar, Jeremy J; Sztein, Marcelo B; Dougan, Gordon; Angus, Brian; Levine, Myron M; Pollard, Andrew J

April 2014

Socio-economic determinants and inequities in coverage and timeliness of early childhood immunisation in rural Ghana. (2014) Gram, Lu; Soremekun, Seyi; ten Asbroek, Augustinus; Manu, Alexander; O'Leary, Maureen; Hill, Zelee; Danso, Samuel; Amenga-Etego, Seeba; Owusu-Agyei, Seth; Kirkwood, Betty R

The Clostridium difficile PCR ribotype 027 lineage: a pathogen on the move. (2014) Valiente, E; Cairns, MD; Wren, BW

Multiplex PCR assay for unequivocal differentiation of Actinobacillus pleuropneumoniae serovars 1 to 3, 5 to 8, 10, and 12. (2014) Bossé, Janine T; Li, Yanwen; Angen, Øystein; Weinert, Lucy A; Chaudhuri, Roy R; Holden, Matthew T; Williamson, Susanna M; Maskell, Duncan J; Tucker, Alexander W; Wren, Brendan W; Rycroft, Andrew N; Langford, Paul R; BRaDP1T consortium

Parallel independent evolution of pathogenicity within the genus Yersinia. (2014) Reuter, Sandra; Connor, Thomas R; Barquist, Lars; Walker, Danielle; Feltwell, Theresa; Harris, Simon R; Fookes, Maria; Hall, Miquette E; Petty, Nicola K; Fuchs, Thilo M; Corander, Jukka; Dufour, Muriel; Ringwood, Tamara; Savin, Cyril; Bouchier, Christiane; Martin, Liliane; Miettinen, Minna; Shubin, Mikhail; Riehm, Julia M; Laukkanen-Ninios, Riikka; Sihvonen, Leila M; Siitonen, Anja; Skurnik, Mikael; Falcão, Juliana Pfrimer; Fukushima, Hiroshi; Scholz, Holger C; Prentice, Michael B; Wren, Brendan W; Parkhill, Julian; Carniel, Elisabeth; Achtman, Mark; McNally, Alan; Thomson, Nicholas R

Prevalence and determinants of antenatal depression among pregnant women in a predominantly rural population in Ghana: the DON population-based study. (2014) Weobong, Benedict; Soremekun, Seyi; Ten Asbroek, Augustinus Ha; Amenga-Etego, Seeba; Danso, Samuel; Owusu-Agyei, Seth; Prince, Martin; Kirkwood, Betty R

Biomedicine and biotechnology: public health impact. (2014) Ganguly, Nirmal K; Croft, Simon; Singh, Lalji; Sinha, Subrata; Balganesh, Tanjore

Dynamics of the antibody response to Plasmodium falciparum infection in African children. (2014) White, Michael T; Griffin, Jamie T; Akpogheneta, Onome; Conway, David J; Koram, Kwadwo A; Riley, Eleanor M; Ghani, Azra C

Factors affecting immunogenicity of BCG in infants, a study in Malawi, The Gambia and the UK. (2014) Hur, Yun-Gyoung; Gorak-Stolinska, Patricia; Lalor, Maeve K; Mvula, Hazzie; Floyd, Sian; Raynes, John; Ben-Smith, Anne; Fitchett, Joseph R; Flanagan, Katie L; Burl, Sarah; Ota, Martin O; Crampin, Amelia C; Smith, Steven G; Dockrell, Hazel M

SVAMP: sequence variation analysis, maps and phylogeny. (2014) Naeem, Raeece; Hidayah, Lailatul; Preston, Mark D; Clark, Taane G; Pain, Arnab

Staphylococcal phenotypes induced by naturally occurring and synthetic membrane-interactive polyphenolic β-lactam resistance modifiers. (2014) Palacios, Lucia; Rosado, Helena; Micol, Vicente; Rosato, Adriana E; Bernal, Patricia; Arroyo, Raquel; Grounds, Helen; Anderson, James C; Stabler, Richard A; Taylor, Peter W

A GC1 Acinetobacter baumannii isolate carrying AbaR3 and the aminoglycoside resistance transposon TnaphA6 in a conjugative plasmid. (2014) Hamidian, Mohammad; Holt, Kathryn E; Pickard, Derek; Dougan, Gordon; Hall, Ruth M

March 2014

Draft genome sequences of the type strains of Shigella flexneri held at Public Health England: comparison of classical phenotypic and novel molecular assays with whole genome sequence. (2014) Ashton, Philip M; Baker, Kate S; Gentle, Amy; Wooldridge, David J; Thomson, Nicholas R; Dallman, Timothy J; Jenkins, Claire

Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility. (2014) Kan, Andrey; Tan, Yan-Hong; Angrisano, Fiona; Hanssen, Eric; Rogers, Kelly L; Whitehead, Lachlan; Mollard, Vanessa P; Cozijnsen, Anton; Delves, Michael J; Crawford, Simon; Sinden, Robert E; McFadden, Geoffrey I; Leckie, Christopher; Bailey, James; Baum, Jake

Defining the geographical range of the Plasmodium knowlesi reservoir. (2014) Moyes, Catherine L; Henry, Andrew J; Golding, Nick; Huang, Zhi; Singh, Balbir; Baird, J Kevin; Newton, Paul N; Huffman, Michael; Duda, Kirsten A; Drakeley, Chris J; Elyazar, Iqbal RF; Anstey, Nicholas M; Chen, Qijun; Zommers, Zinta; Bhatt, Samir; Gething, Peter W; Hay, Simon I

Activity of anti-cancer protein kinase inhibitors against Leishmania spp. (2014) Sanderson, Lisa; Yardley, Vanessa; Croft, Simon L

TANDEM: understanding diabetes and tuberculosis. (2014) van Crevel, Reinout; Dockrell, Hazel M; TANDEM Consortium

Exploring the biological and chemical complexity of the ligases. (2014) Holliday, Gemma L; Rahman, Syed Asad; Furnham, Nicholas; Thornton, Janet M

Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda. (2014) Kilama, Maxwell; Smith, David L; Hutchinson, Robert; Kigozi, Ruth; Yeka, Adoke; Lavoy, Geoff; Kamya, Moses R; Staedke, Sarah G; Donnelly, Martin J; Drakeley, Chris; Greenhouse, Bryan; Dorsey, Grant; Lindsay, Steve W

Genome-wide analysis of selection on the malaria parasite Plasmodium falciparum in West African populations of differing infection endemicity. (2014) Mobegi, Victor A; Duffy, Craig W; Amambua-Ngwa, Alfred; Loua, Kovana M; Laman, Eugene; Nwakanma, Davis C; MacInnis, Bronwyn; Aspeling-Jones, Harvey; Murray, Lee; Clark, Taane G; Kwiatkowski, Dominic P; Conway, David J

Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research. (2014) Grüring, Christof; Moon, Robert W; Lim, Caeul; Holder, Anthony A; Blackman, Michael J; Duraisingh, Manoj T

Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites. (2014) Brochet, Mathieu; Collins, Mark O; Smith, Terry K; Thompson, Eloise; Sebastian, Sarah; Volkmann, Katrin; Schwach, Frank; Chappell, Lia; Gomes, Ana Rita; Berriman, Matthew; Rayner, Julian C; Baker, David A; Choudhary, Jyoti; Billker, Oliver

February 2014

Significantly lower anti-Leishmania IgG responses in Sudanese versus Indian visceral leishmaniasis. (2014) Bhattacharyya, Tapan; Bowes, Duncan E; El-Safi, Sayda; Sundar, Shyam; Falconar, Andrew K; Singh, Om Prakash; Kumar, Rajiv; Ahmed, Osman; Boelaert, Marleen; Miles, Michael A

Differences in T-cell responses between Mycobacterium tuberculosis and Mycobacterium africanum-infected patients. (2014) Tientcheu, Leopold D; Sutherland, Jayne S; de Jong, Bouke C; Kampmann, Beate; Jafali, James; Adetifa, Ifedayo M; Antonio, Martin; Dockrell, Hazel M; Ota, Martin O

PolyTB: a genomic variation map for Mycobacterium tuberculosis. (2014) Coll, Francesc; Preston, Mark; Guerra-Assunção, José Afonso; Hill-Cawthorn, Grant; Harris, David; Perdigão, João; Viveiros, Miguel; Portugal, Isabel; Drobniewski, Francis; Gagneux, Sebastien; Glynn, Judith R; Pain, Arnab; Parkhill, Julian; McNerney, Ruth; Martin, Nigel; Clark, Taane G

Targeting Plasmodium falciparum protein kinases with adenosine analogue-oligoarginine conjugates. (2014) Lavogina, Darja; Budu, Alexandre; Enkvist, Erki; Hopp, Christine S; Baker, David A; Langsley, Gordon; Garcia, Celia RS; Uri, Asko

Emergence of the GII-4 Norovirus Sydney2012 strain in England, winter 2012-2013. (2014) Allen, David J; Adams, Natalie L; Aladin, Farah; Harris, John P; Brown, David WG

Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections. (2014) Mosha, Jacklin F; Sturrock, Hugh JW; Greenwood, Brian; Sutherland, Colin J; Gadalla, Nahla B; Atwal, Sharan; Hemelaar, Simon; Brown, Joelle M; Drakeley, Chris; Kibiki, Gibson; Bousema, Teun; Chandramohan, Daniel; Gosling, Roland D

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. (2014) Moule, Madeleine G; Hemsley, Claudia M; Seet, Qihui; Guerra-Assunção, José Afonso; Lim, Jiali; Sarkar-Tyson, Mitali; Clark, Taane G; Tan, Patrick BO; Titball, Richard W; Cuccui, Jon; Wren, Brendan W

C-reactive protein is essential for innate resistance to pneumococcal infection. (2014) Simons, J Paul; Loeffler, Jutta M; Al-Shawi, Raya; Ellmerich, Stephan; Hutchinson, Winston L; Tennent, Glenys A; Petrie, Aviva; Raynes, John G; de Souza, J Brian; Lawrence, Rachel A; Read, Kevin D; Pepys, Mark B

Signatures of malaria vaccine efficacy in ageing murine immune memory. (2014) Haussig, JM; Burgold, J; Hafalla, JCR; Matuschewski, K; Kooij, TWA

Identification of a marker for two lineages within the GC1 clone of Acinetobacter baumannii. (2014) Hamidian, Mohammad; Wynn, Matthew; Holt, Kathryn E; Pickard, Derek; Dougan, Gordon; Hall, Ruth M

Plasmid deficiency in urogenital isolates of Chlamydia trachomatis reduces infectivity and virulence in a mouse model. (2014) Sigar, Ira M; Schripsema, Justin H; Wang, Yibing; Clarke, Ian N; Cutcliffe, Lesley T; Seth-Smith, Helena MB; Thomson, Nicholas R; Bjartling, Carina; Unemo, Magnus; Persson, Kenneth; Ramsey, Kyle H

Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children. (2014) Moxon, Christopher A; Chisala, Ngawina V; Wassmer, Samuel C; Taylor, Terrie E; Seydel, Karl B; Molyneux, Malcolm E; Faragher, Brian; Kennedy, Neil; Toh, Cheng-Hock; Craig, Alister G; Heyderman, Robert S

January 2014

Transmission of Dientamoeba fragilis: pinworm or cysts? (2014) Clark, C Graham; Röser, Dennis; Stensvold, C Rune

Biological roles of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. (2014) van Alphen, Lieke B; Wenzel, Cory Q; Richards, Michele R; Fodor, Christopher; Ashmus, Roger A; Stahl, Martin; Karlyshev, Andrey V; Wren, Brendan W; Stintzi, Alain; Miller, William G; Lowary, Todd L; Szymanski, Christine M

African origin of the malaria parasite Plasmodium vivax. (2014) Liu, Weimin; Li, Yingying; Shaw, Katharina S; Learn, Gerald H; Plenderleith, Lindsey J; Malenke, Jordan A; Sundararaman, Sesh A; Ramirez, Miguel A; Crystal, Patricia A; Smith, Andrew G; Bibollet-Ruche, Frederic; Ayouba, Ahidjo; Locatelli, Sabrina; Esteban, Amandine; Mouacha, Fatima; Guichet, Emilande; Butel, Christelle; Ahuka-Mundeke, Steve; Inogwabini, Bila-Isia; Ndjango, Jean-Bosco N; Speede, Sheri; Sanz, Crickette M; Morgan, David B; Gonder, Mary K; Kranzusch, Philip J; Walsh, Peter D; Georgiev, Alexander V; Muller, Martin N; Piel, Alex K; Stewart, Fiona A; Wilson, Michael L; Pusey, Anne E; Cui, Liwang; Wang, Zenglei; Färnert, Anna; Sutherland, Colin J; Nolder, Debbie; Hart, John A; Hart, Terese B; Bertolani, Paco; Gillis, Amethyst; LeBreton, Matthew; Tafon, Babila; Kiyang, John; Djoko, Cyrille F; Schneider, Bradley S; Wolfe, Nathan D; Mpoudi-Ngole, Eitel; Delaporte, Eric; Carter, Richard; Culleton, Richard L; Shaw, George M; Rayner, Julian C; Peeters, Martine; Hahn, Beatrice H; Sharp, Paul M

Optimizing bioluminescence imaging to study protozoan parasite infections. (2014) Taylor, Martin C; Kelly, John M

Benznidazole-resistance in Trypanosoma cruzi: evidence that distinct mechanisms can act in concert. (2014) Campos, Mônica CO; Leon, Leonor L; Taylor, Martin C; Kelly, John M

Salmonella vaccines: lessons from the mouse model or bad teaching? (2014) Strugnell, Richard A; Scott, Timothy A; Wang, Nancy; Yang, Chenying; Peres, Newton; Bedoui, Sammy; Kupz, Andreas

estMOI: estimating multiplicity of infection using parasite deep sequencing data. (2014) Assefa, Samuel A; Preston, Mark D; Campino, Susana; Ocholla, Harold; Sutherland, Colin J; Clark, Taane G

Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit. (2014) Jaudzems, Kristaps; Tars, Kaspars; Maurops, Gundars; Ivdra, Natalija; Otikovs, Martins; Leitans, Janis; Kanepe-Lapsa, Iveta; Domraceva, Ilona; Mutule, Ilze; Trapencieris, Peteris; Blackman, Michael J; Jirgensons, Aigars

EC-BLAST: a tool to automatically search and compare enzyme reactions. (2014) Rahman, Syed Asad; Cuesta, Sergio Martinez; Furnham, Nicholas; Holliday, Gemma L; Thornton, Janet M

Orally active antischistosomal early leads identified from the open access malaria box. (2014) Ingram-Sieber, Katrin; Cowan, Noemi; Panic, Gordana; Vargas, Mireille; Mansour, Nuha R; Bickle, Quentin D; Wells, Timothy NC; Spangenberg, Thomas; Keiser, Jennifer

Screening vaccine formulations for biological activity using fresh human whole blood. (2014) Brookes, Roger H; Hakimi, Jalil; Ha, Yukyung; Aboutorabian, Sepideh; Ausar, Salvador F; Hasija, Manvi; Smith, Steven G; Todryk, Stephen M; Dockrell, Hazel M; Rahman, Nausheen

Adaptive change inferred from genomic population analysis of the ST93 epidemic clone of community-associated methicillin-resistant Staphylococcus aureus. (2014) Stinear, Timothy P; Holt, Kathryn E; Chua, Kyra; Stepnell, Justin; Tuck, Kellie L; Coombs, Geoffrey; Harrison, Paul Francis; Seemann, Torsten; Howden, Benjamin P

2014

Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia. (2014) Alifrangis, Michael; Nag, Sidsel; Schousboe, Mette L; Ishengoma, Deus; Lusingu, John; Pota, Hirva; Kavishe, Reginald A; Pearce, Richard; Ord, Rosalynn; Lynch, Caroline; Dejene, Seyoum; Cox, Jonathan; Rwakimari, John; Minja, Daniel TR; Lemnge, Martha M; Roper, Cally

Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis. (2014) Alsford, Sam

Diagnosis of childhood tuberculosis and host RNA expression in Africa. (2014) Anderson, Suzanne T; Kaforou, Myrsini; Brent, Andrew J; Wright, Victoria J; Banwell, Claire M; Chagaluka, George; Crampin, Amelia C; Dockrell, Hazel M; French, Neil; Hamilton, Melissa S; Hibberd, Martin L; Kern, Florian; Langford, Paul R; Ling, Ling; Mlotha, Rachel; Ottenhoff, Tom HM; Pienaar, Sandy; Pillay, Vashini; Scott, J Anthony G; Twahir, Hemed; Wilkinson, Robert J; Coin, Lachlan J; Heyderman, Robert S; Levin, Michael; Eley, Brian ['material/summary:fileicon_text/html' not defined]

Evaluating the implementation of community volunteer assessment and referral of sick babies: lessons learned from the Ghana Newhints home visits cluster randomized controlled trial. (2014) Ansah Manu, Alexander; ten Asbroek, Augustinus; Soremekun, Seyi; Gyan, Thomas; Weobong, Benedict; Tawiah-Agyemang, Charlotte; Danso, Samuel; Amenga-Etego, Seeba; Owusu-Agyei, Seth; Hill, Zelee; Kirkwood, Betty R

Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission. (2014) Baleela, Rania; Llewellyn, Martin S; Fitzpatrick, Sinead; Kuhls, Katrin; Schönian, Gabriele; Miles, Michael A; Mauricio, Isabel L

Emerging paradigms in anti-infective drug design. (2014) Barrett, Michael P; Croft, Simon L

Low-dose primaquine for falciparum malaria. (2014) Bousema, Teun; Eziefula, Alice C; Pett, Helmi; Drakeley, Chris

Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. (2014) Das, Shantanabha; Freier, Anja; Boussoffara, Thouraya; Das, Sushmita; Oswald, Detlef; Losch, Florian O; Selka, Melanie; Sacerdoti-Sierra, Nina; Schönian, Gabriele; Wiesmüller, Karl-Heinz; Seifert, Karin; Schroff, Matthias; Juhls, Christiane; Jaffe, Charles L; Roy, Syamal; Das, Pradeep; Louzir, Hechmi; Croft, Simon L; Modabber, Farrokh; Walden, Peter

In for the long haul: 20 years of malaria surveillance. (2014) Drakeley, Chris; Lines, Jo

Malaria parasite epigenetics: when virulence and romance collide. (2014) Flueck, Christian; Baker, David A

Identification of possible virulence marker from Campylobacter jejuni isolates. (2014) Harrison, James W; Dung, Tran Thi Ngoc; Siddiqui, Fariha; Korbrisate, Sunee; Bukhari, Habib; Tra, My Phan Vu; Hoang, Nguyen Van Minh; Carrique-Mas, Juan; Bryant, Juliet; Campbell, James I; Studholme, David J; Wren, Brendan W; Baker, Stephen; Titball, Richard W; Champion, Olivia L

Metalloprotein design using genetic code expansion. (2014) Hu, Cheng; Chan, Sunney I; Sawyer, Elizabeth B; Yu, Yang; Wang, Jiangyun

Genome evolution and plasticity of Serratia marcescens, an important multidrug-resistant nosocomial pathogen. (2014) Iguchi, Atsushi; Nagaya, Yutaka; Pradel, Elizabeth; Ooka, Tadasuke; Ogura, Yoshitoshi; Katsura, Keisuke; Kurokawa, Ken; Oshima, Kenshiro; Hattori, Masahira; Parkhill, Julian; Sebaihia, Mohamed; Coulthurst, Sarah J; Gotoh, Naomasa; Thomson, Nicholas R; Ewbank, Jonathan J; Hayashi, Tetsuya

A transcriptional switch underlies commitment to sexual development in malaria parasites. (2014) Kafsack, Björn FC; Rovira-Graells, Núria; Clark, Taane G; Bancells, Cristina; Crowley, Valerie M; Campino, Susana G; Williams, April E; Drought, Laura G; Kwiatkowski, Dominic P; Baker, David A; Cortés, Alfred; Llinás, Manuel

Poly(methacrylic acid) complexation of amphotericin B to treat neglected diseases. (2014) Les, Karolina Alicja; Mohamed-Ahmed, Abeer HA; Balan, Sibu; Choi, Ji-won; Martin, Denis; Yardley, Vanessa; Powell, Keith; Godwin, Antony; Brocchini, Steve

The association between the ratio of monocytes: lymphocytes and risk of tuberculosis among HIV-infected postpartum women. (2014) Naranbhai, Vivek; Moodley, Dhayendre; Chipato, Tsungai; Stranix-Chibanda, Lynda; Nakabaiito, Clemensia; Kamateeka, Moreen; Musoke, Philippa; Manji, Karim; George, Kathleen; Emel, Lynda M; Richardson, Paul; Andrew, Philip; Fowler, MaryGlenn; Fletcher, Helen; McShane, Helen; Coovadia, Hoosen M; Hill, Adrian VS; HPTN 046 Protocol Team

Seroconversion for infectious pathogens among UK military personnel deployed to Afghanistan, 2008-2011. (2014) Newman, Edmund NC; Johnstone, Penelope; Bridge, Hannah; Wright, Deborah; Jameson, Lisa; Bosworth, Andrew; Hatch, Rebecca; Hayward-Karlsson, Jenny; Osborne, Jane; Bailey, Mark S; Green, Andrew; Ross, David; Brooks, Tim; Hewson, Roger

Synthesis of cyclohexapeptides as antimalarial and anti-trypanosomal agents. (2014) Peña, S; Fagundez, C; Medeiros, A; Comini, M; Scarone, L; Sellanes, D; Manta, E; Tulla-Puche, J; Albericio, F; Stewart, L; Yardley, V; Serra, G

Molecular surveillance for artemisinin resistance in Africa. (2014) Roper, Cally; Alifrangis, Michael; Ariey, Frederic; Talisuna, Ambrose; Menard, Didier; Mercereau-Puijalon, Odile; Ringwald, Pascal

Measuring changes in Plasmodium falciparum transmission: precision, accuracy and costs of metrics. (2014) Tusting, Lucy S; Bousema, Teun; Smith, David L; Drakeley, Chris

Community-based sampling methods for surveillance of the Chagas disease vector, Triatoma dimidiata (Hemiptera: Reduviidae: Triatominae). (2014) Weeks, ENI; Davies, C; Rosales, C Cordón; Yeo, M; Gezan, SA; Parra-Henao, G; Cameron, MM

Shared characteristics between Mycobacterium tuberculosis and fungi contribute to virulence. (2014) Willcocks, Sam; Wren, Brendan W