Items where Faculty or Department is "Department of Infection Biology"

LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Immunology and Infection (-2019) (972)

Dept of Pathogen Molecular Biology (-2019) (1192) Month Authors/Creators Item Type Full Text

Article

Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development. (2008) Lal, Kalpana; Delves, Michael J; Bromley, Elizabeth; Wastling, Jonathan M; Tomley, Fiona M; Sinden, Robert E

The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay. (2008) Hjerde, Erik; Lorentzen, Marit Sjo; Holden, Matthew Tg; Seeger, Kathy; Paulsen, Steinar; Bason, Nathalie; Churcher, Carol; Harris, David; Norbertczak, Halina; Quail, Michael A; Sanders, Suzanne; Thurston, Scott; Parkhill, Julian; Willassen, Nils Peder; Thomson, Nicholas R

Analysis of the role of 13 major fimbrial subunits in colonisation of the chicken intestines by Salmonella enterica serovar Enteritidis reveals a role for a novel locus. (2008) Clayton, Debra J; Bowen, Alison J; Hulme, Scott D; Buckley, Anthony M; Deacon, Victoria L; Thomson, Nicholas R; Barrow, Paul A; Morgan, Eirwen; Jones, Michael A; Watson, Michael; Stevens, Mark P

Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles. (2008) Thuong, Nguyen Thuy Thuong; Dunstan, Sarah J; Chau, Tran Thi Hong; Thorsson, Vesteinn; Simmons, Cameron P; Quyen, Nguyen Than Ha; Thwaites, Guy E; Thi Ngoc Lan, Nguyen; Hibberd, Martin; Teo, Yik Y; Seielstad, Mark; Aderem, Alan; Farrar, Jeremy J; Hawn, Thomas R

Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity. (2008) Stepniewska, Kasia; Price, Ric N; Sutherland, Colin J; Drakeley, Chris J; von Seidlein, Lorenz; Nosten, Francois; White, Nicholas J

PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence. (2008) Gonzalo-Asensio, Jesús; Mostowy, Serge; Harders-Westerveen, Jose; Huygen, Kris; Hernández-Pando, Rogelio; Thole, Jelle; Behr, Marcel; Gicquel, Brigitte; Martín, Carlos

Molecular approaches to field studies of malaria. (2008) Beck, Hans-Peter; Tetteh, Kevin

Cluster of falciparum malaria cases in UK airport. (2008) Rodger, Alison J; Cooke, Graham S; Ord, Rosalynn; Sutherland, Colin J; Pasvol, Geoffrey

Genome evolution of Wolbachia strain wPip from the Culex pipiens group. (2008) Klasson, Lisa; Walker, Thomas; Sebaihia, Mohammed; Sanders, Mandy J; Quail, Michael A; Lord, Angela; Sanders, Susanne; Earl, Julie; O'Neill, Scott L; Thomson, Nicholas; Sinkins, Steven P; Parkhill, Julian

The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants. (2008) Crossman, Lisa C; Gould, Virginia C; Dow, J Maxwell; Vernikos, Georgios S; Okazaki, Aki; Sebaihia, Mohammed; Saunders, David; Arrowsmith, Claire; Carver, Tim; Peters, Nicholas; Adlem, Ellen; Kerhornou, Arnaud; Lord, Angela; Murphy, Lee; Seeger, Katharine; Squares, Robert; Rutter, Simon; Quail, Michael A; Rajandream, Mari-Adele; Harris, David; Churcher, Carol; Bentley, Stephen D; Parkhill, Julian; Thomson, Nicholas R; Avison, Matthew B

Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria. (2008) Osier, Faith HA; Fegan, Gregory; Polley, Spencer D; Murungi, Linda; Verra, Federica; Tetteh, Kevin KA; Lowe, Brett; Mwangi, Tabitha; Bull, Peter C; Thomas, Alan W; Cavanagh, David R; McBride, Jana S; Lanar, David E; Mackinnon, Margaret J; Conway, David J; Marsh, Kevin

Analysis of amino acid variation in the P2 domain of the GII-4 norovirus VP1 protein reveals putative variant-specific epitopes. (2008) Allen, David J; Gray, Jim J; Gallimore, Chris I; Xerry, Jacqueline; Iturriza-Gómara, Miren

Transmission events within outbreaks of gastroenteritis determined through analysis of nucleotide sequences of the P2 domain of genogroup II noroviruses. (2008) Xerry, Jacqueline; Gallimore, Chris I; Iturriza-Gómara, Miren; Allen, David J; Gray, Jim J

Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific. (2008) Akpogheneta, Onome J; Duah, Nancy O; Tetteh, Kevin KA; Dunyo, Samuel; Lanar, David E; Pinder, Margaret; Conway, David J

Establishment of the 1st World Health Organization International Standard for Plasmodium falciparum DNA for nucleic acid amplification technique (NAT)-based assays. (2008) Padley, David J; Heath, Alan B; Sutherland, Colin; Chiodini, Peter L; Baylis, Sally A; Collaborative Study Group

Molecular epidemiology of amebiasis. (2008) Ali, Ibne Karim M; Clark, C Graham; Petri, William A

Tissue invasion by Entamoeba histolytica: evidence of genetic selection and/or DNA reorganization events in organ tropism. (2008) Ali, Ibne Karim M; Solaymani-Mohammadi, Shahram; Akhter, Jasmine; Roy, Shantanu; Gorrini, Chiara; Calderaro, Adriana; Parker, Sarah K; Haque, Rashidul; Petri, William A; Clark, C Graham

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei. (2008) Alsford, Sam; Horn, David

YtxR acts as an overriding transcriptional off switch for the Yersinia enterocolitica Ysc-Yop type 3 secretion system. (2008) Axler-DiPerte, Grace L; Hinchliffe, Stewart J; Wren, Brendan W; Darwin, Andrew J

Fatal wound infection caused by Chromobacterium violaceum in Ho Chi Minh City, Vietnam. (2008) Baker, Stephen; Campbell, James I; Stabler, Richard; Nguyen, Hoang VM; To, Diep S; Nguyen, Dung V; Farrar, Jeremy

Increased gametocytemia after treatment: an early parasitological indicator of emerging sulfadoxine-pyrimethamine resistance in falciparum malaria. (2008) Barnes, Karen I; Little, Francesca; Mabuza, Aaron; Mngomezulu, Nicros; Govere, John; Durrheim, David; Roper, Cally; Watkins, Bill; White, Nicholas J

Assembly and channel opening in a bacterial drug efflux machine. (2008) Bavro, Vassiliy N; Pietras, Zbigniew; Furnham, Nicholas; Pérez-Cano, Laura; Fernández-Recio, Juan; Pei, Xue Yuan; Misra, Rajeev; Luisi, Ben

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age. (2008) Bejon, Philip; Lusingu, John; Olotu, Ally; Leach, Amanda; Lievens, Marc; Vekemans, Johan; Mshamu, Salum; Lang, Trudie; Gould, Jayne; Dubois, Marie-Claude; Demoitié, Marie-Ange; Stallaert, Jean-Francois; Vansadia, Preeti; Carter, Terrell; Njuguna, Patricia; Awuondo, Ken O; Malabeja, Anangisye; Abdul, Omar; Gesase, Samwel; Mturi, Neema; Drakeley, Chris J; Savarese, Barbara; Villafana, Tonya; Ballou, W Ripley; Cohen, Joe; Riley, Eleanor M; Lemnge, Martha M; Marsh, Kevin; von Seidlein, Lorenz

Differences between naive and memory T cell phenotype in Malawian and UK adolescents: a role for Cytomegalovirus? (2008) Ben-Smith, Anne; Gorak-Stolinska, Patricia; Floyd, Sian; Weir, Rosemary E; Lalor, Maeve K; Mvula, Hazzie; Crampin, Amelia C; Wallace, Diana; Beverley, Peter Cl; Fine, Paul Em; Dockrell, Hazel M

A comparison of IFNgamma detection methods used in tuberculosis vaccine trials. (2008) Beveridge, Natalie ER; Fletcher, Helen A; Hughes, Jane; Pathan, Ansar A; Scriba, Thomas J; Minassian, Angela; Sander, Clare R; Whelan, Kathryn T; Dockrell, Hazel M; Hill, Adrian VS; Hanekom, Willem A; McShane, Helen

Bluetongue virus outer capsid protein VP5 interacts with membrane lipid rafts via a SNARE domain. (2008) Bhattacharya, Bishnupriya; Roy, Polly

Chronic intestinal nematode infection exacerbates experimental Schistosoma mansoni infection. (2008) Bickle, Quentin D; Solum, Julie; Helmby, Helena

Malarial proteases and host cell egress: an 'emerging' cascade. (2008) Blackman, Michael J

Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae. (2008) Bousema, J Teun; Drakeley, Chris J; Mens, Petra F; Arens, Theo; Houben, Rein; Omar, Sabah A; Gouagna, Louis C; Schallig, Henk; Sauerwein, Robert W

Development of reverse genetics systems for bluetongue virus: recovery of infectious virus from synthetic RNA transcripts. (2008) Boyce, Mark; Celma, Cristina CP; Roy, Polly

Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa. (2008) Brookes, Roger H; Hill, Philip C; Owiafe, Patrick K; Ibanga, Hannah B; Jeffries, David J; Donkor, Simon A; Fletcher, Helen A; Hammond, Abdulrahman S; Lienhardt, Christian; Adegbola, Richard A; McShane, Helen; Hill, Adrian VS

Validating discovered Cis-acting regulatory genetic variants: application of an allele specific expression approach to HapMap populations. (2008) Campino, Susana; Forton, Julian; Raj, Srilakshmi; Mohr, Bert; Auburn, Sarah; Fry, Andrew; Mangano, Valentina D; Vandiedonck, Claire; Richardson, Anna; Rockett, Kirk; Clark, Taane G; Kwiatkowski, Dominic P

Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs. (2008) Camps, Pelayo; Duque, María D; Vázquez, Santiago; Naesens, Lieve; De Clercq, Erik; Sureda, Francesc X; López-Querol, Marta; Camins, Antoni; Pallàs, Mercè; Prathalingam, S Radhika; Kelly, John M; Romero, Vanessa; Ivorra, Dolores; Cortés, Diego

Anopheles gambiae complex along The Gambia river, with particular reference to the molecular forms of An. gambiae s.s. (2008) Caputo, Beniamino; Nwakanma, Davis; Jawara, Musa; Adiamoh, Majidah; Dia, Ibrahima; Konate, Lassana; Petrarca, Vincenzo; Conway, David J; della Torre, Alessandra

PbSR is synthesized in macrogametocytes and involved in formation of the malaria crystalloids. (2008) Carter, Victoria; Shimizu, Shoichi; Arai, Meiji; Dessens, Johannes T

Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis. (2008) Ceesay, Serign J; Casals-Pascual, Climent; Erskine, Jamie; Anya, Samuel E; Duah, Nancy O; Fulford, Anthony JC; Sesay, Sanie SS; Abubakar, Ismaela; Dunyo, Samuel; Sey, Omar; Palmer, Ayo; Fofana, Malang; Corrah, Tumani; Bojang, Kalifa A; Whittle, Hilton C; Greenwood, Brian M; Conway, David J

Cryptic diversity in intestinal protists. (2008) Clark, CG

An Evolutionary Algorithm to Find Associations in Dense Genetic Maps. (2008) Clark, Taane G; De Iorio, Maria; Griffths, Robert C

Synthesis and antiprotozoal evaluation of new N4-(benzyl)spermidyl-linked bis(1,3,5-thiadiazinane-2-thiones). (2008) Coro, Julieta; Little, Susan; Yardley, Vanessa; Suárez, Margarita; Rodríguez, Hortensia; Martín, Nazario; Perez-Pineiro, Rolando

Dried blood spots as a source of anti-malarial antibodies for epidemiological studies. (2008) Corran, Patrick H; Cook, Jackie; Lynch, Caroline; Leendertse, Heleen; Manjurano, Alphaxard; Griffin, Jamie; Cox, Jonathan; Abeku, Tarekegn; Bousema, Teun; Ghani, Azra C; Drakeley, Chris; Riley, Eleanor

IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection. (2008) Couper, Kevin N; Blount, Daniel G; Wilson, Mark S; Hafalla, Julius C; Belkaid, Yasmine; Kamanaka, Masahito; Flavell, Richard A; de Souza, J Brian; Riley, Eleanor M

Plasmodium knowlesi malaria in humans is widely distributed and potentially life threatening. (2008) Cox-Singh, Janet; Davis, Timothy ME; Lee, Kim-Sung; Shamsul, Sunita SG; Matusop, Asmad; Ratnam, Shanmuga; Rahman, Hasan A; Conway, David J; Singh, Balbir

Kinetoplastida: new therapeutic strategies. (2008) Croft, SL

PKDL--a drug related phenomenon? (2008) Croft, Simon L

Assessing the role of p-cresol tolerance in Clostridium difficile. (2008) Dawson, Lisa F; Stabler, Richard A; Wren, Brendan W

Gene expression profiling of Leishmania (Leishmania) donovani: overcoming technical variation and exploiting biological variation. (2008) Decuypere, S; Vanaerschot, M; Rijal, S; Yardley, V; Maes, L; de Doncker, S; Chappuis, F; Dujardin, J-C

Real vaccines in the real world: tuberculosis vaccines move south. (2008) Dockrell, Hazel M

Global collaborations in leprosy research--the future is connected. (2008) Dockrell, Hazel M; Oskam, Linda; Richardus, Jan Hendrik

Roles of proteases during invasion and egress by Plasmodium and Toxoplasma. (2008) Dowse, Timothy J; Koussis, Konstantinos; Blackman, Michael J; Soldati-Favre, Dominique

Out with the old, in with the new: the utility of rapid diagnostic tests for malaria diagnosis in Africa. (2008) Drakeley, Chris; Reyburn, Hugh

Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress. (2008) Emerson, Jenny E; Stabler, Richard A; Wren, Brendan W; Fairweather, Neil F

Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents. (2008) Fattorusso, Caterina; Campiani, Giuseppe; Kukreja, Gagan; Persico, Marco; Butini, Stefania; Romano, Maria Pia; Altarelli, Maria; Ros, Sindu; Brindisi, Margherita; Savini, Luisa; Novellino, Ettore; Nacci, Vito; Fattorusso, Ernesto; Parapini, Silvia; Basilico, Nicoletta; Taramelli, Donatella; Yardley, Vanessa; Croft, Simon; Borriello, Marianna; Gemma, Sandra

A panel of ten microsatellite loci for the Chagas disease vector Rhodnius prolixus (Hemiptera: Reduviidae). (2008) Fitzpatrick, S; Watts, PC; Feliciangeli, MD; Miles, MA; Kemp, SJ

Molecular genetics reveal that silvatic Rhodnius prolixus do colonise rural houses. (2008) Fitzpatrick, Sinead; Feliciangeli, Maria Dora; Sanchez-Martin, Maria J; Monteiro, Fernando A; Miles, Michael A

Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-beta1. (2008) Fletcher, Helen A; Pathan, Ansar A; Berthoud, Tamara K; Dunachie, Susanna J; Whelan, Kathryn T; Alder, Nicola C; Sander, Clare R; Hill, Adrian VS; McShane, Helen

Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum. (2008) Friebolin, Wolfgang; Jannack, Beate; Wenzel, Nicole; Furrer, Julien; Oeser, Thomas; Sanchez, Cecilia P; Lanzer, Michael; Yardley, Vanessa; Becker, Katja; Davioud-Charvet, Elisabeth

Comparative modelling by restraint-based conformational sampling. (2008) Furnham, Nicholas; de Bakker, Paul Iw; Gore, Swanand; Burke, David F; Blundell, Tom L

Role of the Cj1371 periplasmic protein and the Cj0355c two-component regulator in the Campylobacter jejuni NCTC 11168 response to oxidative stress caused by paraquat. (2008) Garénaux, Amélie; Guillou, Sandrine; Ermel, Gwennola; Wren, Brendan; Federighi, Michel; Ritz, Magali

Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies. (2008) Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Kukreja, Gagan; Coccone, Salvatore Sanna; Joshi, Bhupendra P; Persico, Marco; Nacci, Vito; Fiorini, Isabella; Novellino, Ettore; Fattorusso, Ernesto; Taglialatela-Scafati, Orazio; Savini, Luisa; Taramelli, Donatella; Basilico, Nicoletta; Parapini, Silvia; Morace, Giulia; Yardley, Vanessa; Croft, Simon; Coletta, Massimiliano; Marini, Stefano; Fattorusso, Caterina

Effective malaria control: better burden estimates needed. (2008) Gosling, Roly D; Drakeley, Chris J; Chandramohan, Daniel

Presumptive treatment of fever cases as malaria: help or hindrance for malaria control? (2008) Gosling, Roly D; Drakeley, Christopher J; Mwita, Alex; Chandramohan, Daniel

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations. (2008) Hanekom, Willem A; Dockrell, Hazel M; Ottenhoff, Tom HM; Doherty, T Mark; Fletcher, Helen; McShane, Helen; Weichold, Frank F; Hoft, Dan F; Parida, Shreemanta K; Fruth, Uli J

Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa. (2008) Hawkridge, Tony; Scriba, Thomas J; Gelderbloem, Sebastian; Smit, Erica; Tameris, Michele; Moyo, Sizulu; Lang, Trudie; Veldsman, Ashley; Hatherill, Mark; Merwe, Linda van der; Fletcher, Helen A; Mahomed, Hassan; Hill, Adrian VS; Hanekom, Willem A; Hussey, Gregory D; McShane, Helen

The importance of the Rcs phosphorelay in the survival and pathogenesis of the enteropathogenic yersiniae. (2008) Hinchliffe, Stewart J; Howard, Sarah L; Huang, Yahui H; Clarke, David J; Wren, Brendan W

Genome-wide significance for dense SNP and resequencing data. (2008) Hoggart, Clive J; Clark, Taane G; De Iorio, Maria; Whittaker, John C; Balding, David J

High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi. (2008) Holt, Kathryn E; Parkhill, Julian; Mazzoni, Camila J; Roumagnac, Philippe; Weill, François-Xavier; Goodhead, Ian; Rance, Richard; Baker, Stephen; Maskell, Duncan J; Wain, John; Dolecek, Christiane; Achtman, Mark; Dougan, Gordon

Dry season ecology of Anopheles gambiae complex mosquitoes in The Gambia. (2008) Jawara, Musa; Pinder, Margaret; Drakeley, Chris J; Nwakanma, Davis C; Jallow, Ebrima; Bogh, Claus; Lindsay, Steve W; Conway, David J

Sensitivity of IFN-gamma release assay to detect latent tuberculosis infection is retained in HIV-infected patients but dependent on HIV/AIDS progression. (2008) Karam, Farba; Mbow, Fatou; Fletcher, Helen; Senghor, Cheikh S; Coulibaly, Koura D; LeFevre, Andrea M; Ngom Gueye, Ndeye F; Dieye, Tandakha; Sow, Papa S; Mboup, Souleymane; Lienhardt, Christian

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes. (2008) Kawahara, Taemi; Siegel, T Nicolai; Ingram, Alexandra K; Alsford, Sam; Cross, George AM; Horn, David

Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia. (2008) Kirby, Matthew J; Green, Clare; Milligan, Paul M; Sismanidis, Charalambos; Jasseh, Momadou; Conway, David J; Lindsay, Steven W

Study protocol for a three-armed randomized controlled trial to assess whether house screening can reduce exposure to malaria vectors and reduce malaria transmission in The Gambia. (2008) Kirby, Matthew J; Milligan, Paul J; Conway, David J; Lindsay, Steve W

Differentiation and gene flow among European populations of Leishmania infantum MON-1. (2008) Kuhls, Katrin; Chicharro, Carmen; Cañavate, Carmen; Cortes, Sofia; Campino, Lenea; Haralambous, Christos; Soteriadou, Ketty; Pratlong, Francine; Dedet, Jean-Pierre; Mauricio, Isabel; Miles, Michael; Schaar, Matthias; Ochsenreither, Sebastian; Radtke, Oliver A; Schönian, Gabriele

Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. (2008) Lee, J-S; Lee, J-Y; Son, JW; Oh, J-H; Shin, D-M; Yuk, J-M; Song, C-H; Paik, T-H; Jo, E-K

Diagnosis of pulmonary tuberculosis using MTB12 and 38-kDa antigens. (2008) Lee, Ji-Sook; Jo, Eun-Kyeong; Noh, Yeon-Kyeong; Shin, A-Rum; Shin, Dong-Min; Son, Ji Woong; Kim, Hwa-Jung; Song, Chang-Hwa

Rift Valley fever virus structural proteins: expression, characterization and assembly of recombinant proteins. (2008) Liu, Li; Celma, Cristina CP; Roy, Polly

Human Infections with Plasmodium knowlesi, the Philippines. (2008) Luchavez, Jennifer; Espino, Fe; Curameng, Peter; Espina, Ronald; Bell, David; Chiodini, Peter; Nolder, Debbie; Sutherland, Colin; Lee, Kim-Sung; Singh, Balbir

A Declining Burden of Malaria in Northeastern Tanzania. (2008) Lusingu, JP; Vestergaard, L; Mmbando, BP; Gesase, S; Ishengoma, D; Drakeley, C; Magistrado, P; Kitua, AY; Lemnge, MM; Theander, TG

Emergence of a dhfr mutation conferring high-level drug resistance in Plasmodium falciparum populations from southwest Uganda. (2008) Lynch, Caroline; Pearce, Richard; Pota, Hirva; Cox, Jonathan; Abeku, Tarekegn A; Rwakimari, John; Naidoo, Inbarani; Tibenderana, James; Roper, Cally

Meclonazepam analogues as potential new antihelmintic agents. (2008) Mahajan, Aman; Kumar, Vipan; Mansour, Nuha RN; Bickle, Quentin; Chibale, Kelly

Infection rates and genotypes of Trypanosoma rangeli and T. cruzi infecting free-ranging Saguinus bicolor (Callitrichidae), a critically endangered primate of the Amazon Rainforest. (2008) Maia da Silva, F; Naiff, RD; Marcili, A; Gordo, M; D'Affonseca Neto, JA; Naiff, MF; Franco, AMR; Campaner, M; Valente, V; Valente, SA; Camargo, EP; Teixeira, MMG; Miles, MA

Interferon regulatory factor-1 polymorphisms are associated with the control of Plasmodium falciparum infection. (2008) Mangano, VD; Luoni, G; Rockett, KA; Sirima, BS; Konaté, A; Forton, J; Clark, TG; Bancone, G; Sadighi Akha, E; Kwiatkowski, DP; Modiano, D

Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. (2008) McRobert, Louisa; Taylor, Cathy J; Deng, Wensheng; Fivelman, Quinton L; Cummings, Ross M; Polley, Spencer D; Billker, Oliver; Baker, David A

Entamoeba shows reversible variation in ploidy under different growth conditions and between life cycle phases. (2008) Mukherjee, Chandrama; Clark, C Graham; Lohia, Anuradha

Manipulation of the bluetongue virus tubules for immunogen delivery. (2008) Murphy, Aileen; Roy, Polly

Antiplasmodial, beta-haematin inhibition, antitrypanosomal and cytotoxic activity in vitro of novel 4-aminoquinoline 2-imidazolines. (2008) Musonda, Chitalu C; Yardley, Vanessa; de Souza, Renata C Carvalho; Ncokazi, Kanyile; Egan, Timothy J; Chibale, Kelly

Overuse of artemisinin-combination therapy in Mto wa Mbu (river of mosquitoes), an area misinterpreted as high endemic for malaria. (2008) Mwanziva, Charles; Shekalaghe, Seif; Ndaro, Arnold; Mengerink, Bianca; Megiroo, Simon; Mosha, Frank; Sauerwein, Robert; Drakeley, Chris; Gosling, Roly; Bousema, Teun

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate. (2008) Nanayakkara, NP Dhammika; Ager, Arba L; Bartlett, Marilyn S; Yardley, Vanessa; Croft, Simon L; Khan, Ikhlas A; McChesney, James D; Walker, Larry A

Analysis of association of the TIRAP (MAL) S180L variant and tuberculosis in three populations. (2008) Nejentsev, Sergey; Thye, Thorsten; Szeszko, Jeffrey S; Stevens, Helen; Balabanova, Yanina; Chinbuah, Amanua M; Hibberd, Martin; van de Vosse, Esther; Alisjahbana, Bachti; van Crevel, Reinout; Ottenhoff, Tom HM; Png, Eileen; Drobniewski, Francis; Todd, John A; Seielstad, Mark; Horstmann, Rolf D

Reversed chloroquines based on the 3,4-dihydropyrimidin-2(1H)-one scaffold: synthesis and evaluation for antimalarial, beta-haematin inhibition, and cytotoxic activity. (2008) October, Natasha; Watermeyer, Nicholas D; Yardley, Vanessa; Egan, Timothy J; Ncokazi, Kanyile; Chibale, Kelly

Modelling the impact of artemisinin combination therapy and long-acting treatments on malaria transmission intensity. (2008) Okell, Lucy C; Drakeley, Chris J; Bousema, Teun; Whitty, Christopher JM; Ghani, Azra C

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. (2008) Okell, Lucy C; Drakeley, Chris J; Ghani, Azra C; Bousema, Teun; Sutherland, Colin J

ama1 genes of sympatric Plasmodium vivax and P. falciparum from Venezuela differ significantly in genetic diversity and recombination frequency. (2008) Ord, Rosalynn L; Tami, Adriana; Sutherland, Colin J

Molecular methods for distinguishing between relapse and reinfection in leprosy. (2008) Oskam, Linda; Dockrell, Hazel M; Brennan, Patrick J; Gillis, Tom; Vissa, Vara; Richardus, Jan Hendrik; IDEAL Consortium

The genome of the simian and human malaria parasite Plasmodium knowlesi. (2008) Pain, A; Böhme, U; Berry, AE; Mungall, K; Finn, RD; Jackson, AP; Mourier, T; Mistry, J; Pasini, EM; Aslett, MA; Balasubrammaniam, S; Borgwardt, K; Brooks, K; Carret, C; Carver, TJ; Cherevach, I; Chillingworth, T; Clark, TG; Galinski, MR; Hall, N; Harper, D; Harris, D; Hauser, H; Ivens, A; Janssen, CS; Keane, T; Larke, N; Lapp, S; Marti, M; Moule, S; Meyer, IM; Ormond, D; Peters, N; Sanders, M; Sanders, S; Sargeant, TJ; Simmonds, M; Smith, F; Squares, R; Thurston, S; Tivey, AR; Walker, D; White, B; Zuiderwijk, E; Churcher, C; Quail, MA; Cowman, AF; Turner, CMR; Rajandream, MA; Kocken, CHM; Thomas, AW; Newbold, CI; Barrell, BG; Berriman, M

Synthesis of conformationally constrained adamantane imidazolines with trypanocidal activity. (2008) Papanastasiou, Ioannis; Tsotinis, Andrew; Foscolos, George B; Prathalingam, S Radhika; Kelly, John M

Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives. (2008) Papanastasiou, Ioannis; Tsotinis, Andrew; Kolocouris, Nicolas; Prathalingam, S Radhika; Kelly, John M

Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite. (2008) Piacenza, Lucía; Peluffo, Gonzalo; Alvarez, María Noel; Kelly, John M; Wilkinson, Shane R; Radi, Rafael

Structure and mechanism of drug efflux machinery in Gram negative bacteria. (2008) Pietras, Zbigniew; Bavro, Vassiliy N; Furnham, Nicholas; Pellegrini-Calace, Marialuisa; Milner-White, E James; Luisi, Ben F

Amebiasis. (2008) Pritt, Bobbi S; Clark, C Graham

Analysis of two genomes from the mitochondrion-like organelle of the intestinal parasite Blastocystis: complete sequences, gene content, and genome organization. (2008) Pérez-Brocal, Vicente; Clark, C Graham

Structural basis for inhibition of homologous recombination by the RecX protein. (2008) Ragone, Stefania; Maman, Joseph D; Furnham, Nicholas; Pellegrini, Luca

Differential effect of regional drug pressure on dihydrofolate reductase and dihydropteroate synthetase mutations in southern Mozambique. (2008) Raman, Jaishree; Sharp, Brian; Kleinschmidt, Immo; Roper, Cally; Streat, Elizabeth; Kelly, Val; Barnes, Karen I

Bluetongue virus: dissection of the polymerase complex. (2008) Roy, Polly

Functional mapping of bluetongue virus proteins and their interactions with host proteins during virus replication. (2008) Roy, Polly

Molecular and structural dissection of emerging bluetongue virus as a guide to novel vaccine development. (2008) Roy, Polly

Virus-like particles as a vaccine delivery system: myths and facts. (2008) Roy, Polly; Noad, Rob

Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. (2008) Saeed, Maha; Roeffen, Will; Alexander, Neal; Drakeley, Christopher J; Targett, Geoffrey AT; Sutherland, Colin J

Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition. (2008) Sawmynaden, Kovilen; Saouros, Savvas; Friedrich, Nikolas; Marchant, Jan; Simpson, Peter; Bleijlevens, Boris; Blackman, Michael J; Soldati-Favre, Dominique; Matthews, Stephen

Improved sensitivity of diagnosis of tuberculosis in patients in Korea via a cocktail enzyme-linked immunosorbent assay containing the abundantly expressed antigens of the K strain of Mycobacterium tuberculosis. (2008) Shin, A-Rum; Shin, Sung Jae; Lee, Kil-Soo; Eom, Sun-Ho; Lee, Seung-Sub; Lee, Byung-Soo; Lee, Ji-Sook; Cho, Sang Nae; Kim, Hwa-Jung

A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children. (2008) Sokhna, Cheikh; Cissé, Badara; Bâ, El Hadj; Milligan, Paul; Hallett, Rachel; Sutherland, Colin; Gaye, Oumar; Boulanger, Denis; Simondon, Kirsten; Simondon, François; Targett, Geoffrey; Lines, Jo; Greenwood, Brian; Trape, Jean-François

The use of proteomics and bioinformatics to identify novel antigens of Mycobacterium leprae towards the development of a rapid diagnostic test for the early detection of leprosy. (2008) Spencer, John S; Kim, Hee Jin; Roa, Rocio Lopez; Marques, Maria AM; da Silva Filho, Renato; Groathouse, Nathan A; Williams, Diana L; Ottenhoff, Thomas HM; Geluk, Annemieke; Cho, Sang-Nae; Gelber, Robert; Dockrell, Hazel M; Cole, Stewart T; Britton, Warwick J; Duthie, Malcolm S; Ireton, Greg; Pessolani, Maria CV; Slayden, Richard A; Brennan, Patrick J

Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. (2008) Stabler, Richard A; Dawson, Lisa F; Oyston, Petra CF; Titball, Richard W; Wade, Jim; Hinds, Jason; Witney, Adam A; Wren, Brendan W

Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences. (2008) Stabler, Richard A; Dawson, Lisa F; Phua, Leslie TH; Wren, Brendan W

Organelles in Blastocystis that blur the distinction between mitochondria and hydrogenosomes. (2008) Stechmann, Alexandra; Hamblin, Karleigh; Pérez-Brocal, Vicente; Gaston, Daniel; Richmond, Gregory S; van der Giezen, Mark; Clark, C Graham; Roger, Andrew J

Kinetoplastids: related protozoan pathogens, different diseases. (2008) Stuart, Ken; Brun, Reto; Croft, Simon; Fairlamb, Alan; Gürtler, Ricardo E; McKerrow, Jim; Reed, Steve; Tarleton, Rick

Comparing highly efficacious antimalarial drugs. (2008) Sutherland, Colin J

Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil. (2008) Sutherland, Colin J; Laundy, Matt; Price, Nicholas; Burke, Martina; Fivelman, Quinton L; Pasvol, Geoffrey; Klein, John L; Chiodini, Peter L

Patterns of evolution in the unique tRNA gene arrays of the genus Entamoeba. (2008) Tawari, Blessing; Ali, Ibne Karim M; Scott, Claire; Quail, Michael A; Berriman, Matthew; Hall, Neil; Clark, C Graham

Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. (2008) Taylor, Cathy J; McRobert, Louisa; Baker, David A

Validation of spermidine synthase as a drug target in African trypanosomes. (2008) Taylor, Martin C; Kaur, Harparkash; Blessington, Bernard; Kelly, John M; Wilkinson, Shane R

Perturbation analysis: a simple method for filtering SNPs with erroneous genotyping in genome-wide association studies. (2008) Teo, YY; Small, KS; Clark, TG; Kwiatkowski, DP

Burkholderia pseudomallei: animal models of infection. (2008) Titball, Richard W; Russell, Paul; Cuccui, Jon; Easton, Anna; Haque, Ashraful; Atkins, Tim; Sarkar-Tyson, Mitali; Harley, Vicki; Wren, Brendan; Bancroft, Gregory J

IMC1b is a putative membrane skeleton protein involved in cell shape, mechanical strength, motility, and infectivity of malaria ookinetes. (2008) Tremp, Annie Z; Khater, Emad I; Dessens, Johannes T

Dengue virus regulates type I interferon signalling in a strain-dependent manner in human cell lines. (2008) Umareddy, Indira; Tang, Kin Fai; Vasudevan, Subhash G; Devi, Shamala; Hibberd, Martin L; Gu, Feng

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. (2008) Veldhoen, Marc; Uyttenhove, Catherine; van Snick, Jacques; Helmby, Helena; Westendorf, Astrid; Buer, Jan; Martin, Bruno; Wilhelm, Christoph; Stockinger, Brigitta

Biomarkers for TB treatment response: challenges and future strategies. (2008) Walzl, Gerhard; Ronacher, Katharina; Djoba Siawaya, Joel Fleury; Dockrell, Hazel M

Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria-possible modulation in vivo by thrombocytopenia. (2008) Wassmer, Samuel Crocodile; Taylor, Terrie; Maclennan, Calman Alexander; Kanjala, Maxwell; Mukaka, Mavuto; Molyneux, Malcolm Edward; Grau, Georges Emile

Gene-specific signatures of elevated non-synonymous substitution rates correlate poorly across the Plasmodium genus. (2008) Weedall, Gareth D; Polley, Spencer D; Conway, David J

Comparison of IFN-gamma responses to mycobacterial antigens as markers of response to BCG vaccination. (2008) Weir, Rosemary E; Fine, Paul EM; Floyd, Sian; Stenson, Sally; Stanley, Carolynne; Branson, Keith; Britton, Warwick J; Huygen, Kris; Singh, Mahavir; Black, Gillian; Dockrell, Hazel M

Persistence of the immune response induced by BCG vaccination. (2008) Weir, Rosemary E; Gorak-Stolinska, Patricia; Floyd, Sian; Lalor, Maeve K; Stenson, Sally; Branson, Keith; Blitz, Rose; Ben-Smith, Anne; Fine, Paul EM; Dockrell, Hazel M

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes. (2008) Wilkinson, Shane R; Taylor, Martin C; Horn, David; Kelly, John M; Cheeseman, Ian

Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface. (2008) Withers-Martinez, Chrislaine; Haire, Lesley F; Hackett, Fiona; Walker, Philip A; Howell, Steven A; Smerdon, Stephen J; Dodson, Guy G; Blackman, Michael J

Antiprotozoal activity of sesquiterpenes from Warburgia ugandensis towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. (2008) Wube, AA; Bucar, F; Gibbons, S; Asres, K; Rattray, L; Croft, SL

Differential cytokine levels and immunoreactivities against Mycobacterium tuberculosis antigens between tuberculous and malignant effusions. (2008) Yang, Chul-Su; Lee, Ji-Sook; Lee, Hye-Mi; Shim, Tae Sun; Son, Ji Woong; Jung, Sung-Soo; Kim, Jun-Sang; Song, Chang-Hwa; Kim, Hwa-Jung; Jo, Eun-Kyeong

Campylobacter jejuni-mediated disease pathogenesis: an update. (2008) Zilbauer, Matthias; Dorrell, Nick; Wren, Brendan W; Bajaj-Elliott, Mona

Design and synthesis of bioactive 1,2-annulated adamantane derivatives. (2008) Zoidis, Grigoris; Tsotinis, Andrew; Kolocouris, Nicolas; Kelly, John M; Prathalingam, S Radhika; Naesens, Lieve; De Clercq, Erik

Concurrent gastro-intestinal nematode infection does not alter the development of experimental cerebral malaria. (2008) de Souza, Brian; Helmby, Helena

The case for hypervirulence through gene deletion in Mycobacterium tuberculosis. (2008) ten Bokum, Annemieke MC; Movahedzadeh, Farahnaz; Frita, Rosangela; Bancroft, Gregory J; Stoker, Neil G