LSHTM Organisational Structure (57264)

Faculty of Infectious and Tropical Diseases (18516)

Department of Infection Biology (5552)

Dept of Immunology and Infection (-2019) (972)

Dept of Pathogen Molecular Biology (-2019) (1192) Month Authors/Creators Item Type Full Text

Article

Plasmodium falciparum merozoite surface protein 3 is a target of allele-specific immunity and alleles are maintained by natural selection. (2006) Polley, Spencer D; Tetteh, Kevin KA; Lloyd, Jennie M; Akpogheneta, Onome J; Greenwood, Brian M; Bojang, Kalifa A; Conway, David J

Resolution of multiclonal infections of Trypanosoma cruzi from naturally infected triatomine bugs and from experimentally infected mice by direct plating on a sensitive solid medium. (2006) Yeo, Matthew; Lewis, Michael D; Carrasco, Hernan J; Acosta, Nidia; Llewellyn, Martin; da Silva Valente, Sebastião Aldo; de Costa Valente, Vera; de Arias, Antonieta Rojas; Miles, Michael A

ModuleFinder and CoReg: alternative tools for linking gene expression modules with promoter sequences motifs to uncover gene regulation mechanisms in plants. (2006) Holt, Kathryn E; Millar, A Harvey; Whelan, James

Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. (2006) Riley, Monica; Abe, Takashi; Arnaud, Martha B; Berlyn, Mary KB; Blattner, Frederick R; Chaudhuri, Roy R; Glasner, Jeremy D; Horiuchi, Takashi; Keseler, Ingrid M; Kosuge, Takehide; Mori, Hirotada; Perna, Nicole T; Plunkett, Guy; Rudd, Kenneth E; Serres, Margrethe H; Thomas, Gavin H; Thomson, Nicholas R; Wishart, David; Wanner, Barry L

The genome of Rhizobium leguminosarum has recognizable core and accessory components. (2006) Young, J Peter W; Crossman, Lisa C; Johnston, Andrew WB; Thomson, Nicholas R; Ghazoui, Zara F; Hull, Katherine H; Wexler, Margaret; Curson, Andrew RJ; Todd, Jonathan D; Poole, Philip S; Mauchline, Tim H; East, Alison K; Quail, Michael A; Churcher, Carol; Arrowsmith, Claire; Cherevach, Inna; Chillingworth, Tracey; Clarke, Kay; Cronin, Ann; Davis, Paul; Fraser, Audrey; Hance, Zahra; Hauser, Heidi; Jagels, Kay; Moule, Sharon; Mungall, Karen; Norbertczak, Halina; Rabbinowitsch, Ester; Sanders, Mandy; Simmonds, Mark; Whitehead, Sally; Parkhill, Julian

Golgi inheritance in mammalian cells is mediated through endoplasmic reticulum export activities. (2006) Altan-Bonnet, Nihal; Sougrat, Rachid; Liu, Wei; Snapp, Erik L; Ward, Theresa; Lippincott-Schwartz, Jennifer

A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme. (2006) Bauer, Holger; Fritz-Wolf, Karin; Winzer, Andreas; Kühner, Sebastian; Little, Susan; Yardley, Vanessa; Vezin, Hervé; Palfey, Bruce; Schirmer, R Heiner; Davioud-Charvet, Elisabeth

The PPD-specific T-cell clonal response in UK and Malawian subjects following BCG vaccination: a new repertoire evolves over 12 months. (2006) Bennett, Andrea R; Gorak-Stolinska, Patricia; Ben-Smith, Anne; Floyd, Sian; de Lara, Catherine M; Weir, Rosemary E; Lalor, Maeve K; Makamo, Kandakuone; Msiska, Glyn K; Crampin, Amelia C; Fine, Paul EM; Dockrell, Hazel M; Beverley, Peter CL

Miltefosine: issues to be addressed in the future. (2006) Berman, J; Bryceson, ADM; Croft, S; Engel, J; Gutteridge, W; Karbwang, J; Sindermann, H; Soto, J; Sundar, S; Urbina, JA

Apolipoproteins as predictors of ischaemic stroke in patients with a previous transient ischaemic attack. (2006) Bhatia, M; Howard, SC; Clark, TG; Neale, R; Qizilbash, N; Murphy, MFG; Rothwell, PM

Immune interactions between mosquitoes and their hosts. (2006) Billingsley, PF; Baird, J; Mitchell, JA; Drakeley, C

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. (2006) Boscardin, Silvia B; Hafalla, Julius CR; Masilamani, Revati F; Kamphorst, Alice O; Zebroski, Henry A; Rai, Urvashi; Morrot, Alexandre; Zavala, Fidel; Steinman, Ralph M; Nussenzweig, Ruth S; Nussenzweig, Michel C

Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparum. (2006) Bousema, J Teun; Schneider, Petra; Gouagna, Louis C; Drakeley, Chris J; Tostmann, Alma; Houben, Rein; Githure, John I; Ord, Rosalynn; Sutherland, Colin J; Omar, Sabah A; Sauerwein, Robert W

Sexual-stage antibody responses to P. falciparum in endemic populations. (2006) Bousema, JT; Drakeley, CJ; Sauerwein, RW

Recovery of infectious bluetongue virus from RNA. (2006) Boyce, Mark; Roy, Polly

The mycobacterium-specific gene Rv2719c is DNA damage inducible independently of RecA. (2006) Brooks, Patricia C; Dawson, Lisa F; Rand, Lucinda; Davis, Elaine O

Modeling the relationship between the population prevalence of Plasmodium falciparum malaria and anemia. (2006) Carneiro, Ilona A; Smith, Thomas; Lusingu, John PA; Malima, Robert; Utzinger, Jürg; Drakeley, Chris J

The effect of altitude on parasite density case definitions for malaria in northeastern Tanzania. (2006) Chandler, Clare IR; Drakeley, Chris J; Reyburn, Hugh; Carneiro, Ilona

Seasonal intermittent preventive treatment with artesunate and sulfadoxine-pyrimethamine for prevention of malaria in Senegalese children: a randomised, placebo-controlled, double-blind trial. (2006) Cissé, Badara; Sokhna, Cheikh; Boulanger, Denis; Milet, Jacqueline; Bâ, El Hadj; Richardson, Keshena; Hallett, Rachel; Sutherland, Colin; Simondon, Kirsten; Simondon, François; Alexander, Neal; Gaye, Oumar; Targett, Geoffrey; Lines, Jo; Greenwood, Brian; Trape, Jean-François

Methods for the investigation of diversity in Entamoeba histolytica. (2006) Clark, C Graham

Unique organisation of tRNA genes in Entamoeba histolytica. (2006) Clark, C Graham; Ali, Ibne Karim M; Zaki, Mehreen; Loftus, Brendan J; Hall, Neil

New insights into the phylogeny of Entamoeba species provided by analysis of four new small-subunit rRNA genes. (2006) Clark, C Graham; Kaffashian, Farrokh; Tawari, Blessing; Windsor, Jeffrey J; Twigg-Flesner, Anke; Davies-Morel, Mina CG; Blessmann, Joerg; Ebert, Frank; Peschel, Babett; Van, An Le; Jackson, Colin J; Macfarlane, Lorna; Tannich, Egbert

Does smoking influence survival in cancer patients through effects on respiratory and vascular disease? (2006) Clark, Taane G; Murphy, Michael FG; Hey, Kate; Drury, Mark; Cheng, KK; Aveyard, Paul

Alkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents. (2006) Coro, Julieta; Atherton, Richard; Little, Susan; Wharton, Hayley; Yardley, Vanessa; Alvarez, Amaury; Súarez, Margarita; Pérez, Rolando; Rodríguez, Hortensia

Current scenario of drug development for leishmaniasis. (2006) Croft, Simon L; Seifert, Karin; Yardley, Vanessa

Drug resistance in leishmaniasis. (2006) Croft, Simon L; Sundar, Shyam; Fairlamb, Alan H

Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. (2006) Cuccui, J; Easton, A; Chu, KK; Bancroft, GJ; Oyston, PCF; Titball, RW; Wren, BW

Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. (2006) Demissie, Abebech; Leyten, Eliane MS; Abebe, Markos; Wassie, Liya; Aseffa, Abraham; Abate, Getahun; Fletcher, Helen; Owiafe, Patrick; Hill, Philip C; Brookes, Roger; Rook, Graham; Zumla, Alimuddin; Arend, Sandra M; Klein, Michel; Ottenhoff, Tom HM; Andersen, Peter; Doherty, T Mark; VACSEL Study Group

Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode. (2006) Doré, Andrew S; Furnham, Nicholas; Davies, Owen R; Sibanda, Bancinyane L; Chirgadze, Dimitri Y; Jackson, Stephen P; Pellegrini, Luca; Blundell, Tom L

Transmission-reducing immunity is inversely related to age in Plasmodium falciparum gametocyte carriers. (2006) Drakeley, CJ; Bousema, JT; Akim, NIJ; Teelen, K; Roeffen, W; Lensen, AH; Bolmer, M; Eling, W; Sauerwein, RW

The epidemiology of Plasmodium falciparum gametocytes: weapons of mass dispersion. (2006) Drakeley, Chris; Sutherland, Colin; Bousema, J Teun; Sauerwein, Robert W; Targett, Geoffrey AT

Gametocytaemia after drug treatment of asymptomatic Plasmodium falciparum. (2006) Dunyo, Samuel; Milligan, Paul; Edwards, Tansy; Sutherland, Colin; Targett, Geoffrey; Pinder, Margaret

Randomised trial of chloroquine/sulphadoxine-pyrimethamine in Gambian children with malaria: impact against multidrug-resistant P. falciparum. (2006) Dunyo, Samuel; Ord, Rosalynn; Hallett, Rachel; Jawara, Musa; Walraven, Gijs; Mesa, Eduardo; Coleman, Rosalind; Sowe, Maimuna; Alexander, Neal; Targett, Geoffrey AT; Pinder, Margaret; Sutherland, Colin J

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection. (2006) Enosse, Sonia; Dobaño, Carlota; Quelhas, Diana; Aponte, John J; Lievens, Marc; Leach, Amanda; Sacarlal, Jahit; Greenwood, Brian; Milman, Jessica; Dubovsky, Filip; Cohen, Joe; Thompson, Ricardo; Ballou, W Ripley; Alonso, Pedro L; Conway, David J; Sutherland, Colin J

Serotype differences and lack of biofilm formation characterize Yersinia pseudotuberculosis infection of the Xenopsylla cheopis flea vector of Yersinia pestis. (2006) Erickson, David L; Jarrett, Clayton O; Wren, Brendan W; Hinnebusch, B Joseph

Synthesis, structure, and biological activity of ferrocenyl carbohydrate conjugates. (2006) Ferreira, Cara L; Ewart, Charles B; Barta, Cheri A; Little, Susan; Yardley, Vanessa; Martins, Candice; Polishchuk, Elena; Smith, Peter J; Moss, John R; Merkel, Michael; Adam, Michael J; Orvig, Chris

Tuberculosis vaccines: current status and future prospects. (2006) Fletcher, Helen; McShane, Helen

Is one solution good enough? (2006) Furnham, Nicholas; Blundell, Tom L; DePristo, Mark A; Terwilliger, Thomas C

Knowledge-based real-space explorations for low-resolution structure determination. (2006) Furnham, Nicholas; Doré, Andrew S; Chirgadze, Dimitri Y; de Bakker, Paul IW; Depristo, Mark A; Blundell, Tom L

In-vitro and in-vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis. (2006) Garnier, Tracy; Brown, Marc B; Lawrence, M Jayne; Croft, Simon L

Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains. (2006) Gemma, Sandra; Kukreja, Gagan; Fattorusso, Caterina; Persico, Marco; Romano, Maria P; Altarelli, Maria; Savini, Luisa; Campiani, Giuseppe; Fattorusso, Ernesto; Basilico, Nicoletta; Taramelli, Donatella; Yardley, Vanessa; Butini, Stefania

Metalloantimalarials: synthesis, X-ray crystal structure of potent antimalarial copper (II) complex of arylazo-4-hydroxy-1,2-naphthoquinone. (2006) Gokhale, Nikhil H; Shirisha, K; Padhye, Subhash B; Croft, Simon L; Kendrick, Howard D; Mckee, Vickie

Immunogenicity of Danish-SSI 1331 BCG vaccine in the UK: comparison with Glaxo-Evans 1077 BCG vaccine. (2006) Gorak-Stolinska, Patricia; Weir, Rosemary E; Floyd, Sian; Lalor, Maeve K; Stenson, Sally; Branson, Keith; Blitz, Rose; Luke, Sarah; Nazareth, Bernadette; Ben-Smith, Anne; Fine, Paul EM; Dockrell, Hazel M

The carbon starvation-inducible genes Rv2557 and Rv2558 of Mycobacterium tuberculosis are not required for long-term survival under carbon starvation and for virulence in SCID mice. (2006) Gordhan, Bhavna G; Smith, Debbie A; Kana, Bavesh D; Bancroft, Gregory; Mizrahi, Valerie

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action. (2006) Gros, Ludovic; Castillo-Acosta, Victor Manuel; Jiménez Jiménez, Carmen; Sealey-Cardona, Marco; Vargas, Sofia; Manuel Estévez, Antonio; Yardley, Vanessa; Rattray, Lauren; Croft, Simon L; Ruiz-Perez, Luis M; Urbina, Julio A; Gilbert, Ian H; González-Pacanowska, Dolores

Evaluation of azasterols as anti-parasitics. (2006) Gros, Ludovic; Lorente, Silvia Orenes; Jimenez, Carmen Jimenez; Yardley, Vanessa; Rattray, Lauren; Wharton, Hayley; Little, Susan; Croft, Simon L; Ruiz-Perez, Luis M; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H

Priming of CD8+ T cell responses following immunization with heat-killed Plasmodium sporozoites. (2006) Hafalla, Julius CR; Rai, Urvashi; Morrot, Alexandre; Bernal-Rubio, Dabeiba; Zavala, Fidel; Rodriguez, Ana

Chloroquine/sulphadoxine-pyrimethamine for gambian children with malaria: transmission to mosquitoes of multidrug-resistant Plasmodium falciparum. (2006) Hallett, Rachel L; Dunyo, Samuel; Ord, Rosalynn; Jawara, Musa; Pinder, Margaret; Randall, Anna; Alloueche, Ali; Walraven, Gijs; Targett, Geoffrey AT; Alexander, Neal; Sutherland, Colin J

A live experimental vaccine against Burkholderia pseudomallei elicits CD4+ T cell-mediated immunity, priming T cells specific for 2 type III secretion system proteins. (2006) Haque, Ashraful; Chu, Karen; Easton, Anna; Stevens, Mark P; Galyov, Edouard E; Atkins, Tim; Titball, Rick; Bancroft, Gregory J

Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. (2006) Haque, Ashraful; Easton, Anna; Smith, Debbie; O'Garra, Anne; Van Rooijen, Nico; Lertmemongkolchai, Ganjana; Titball, Richard W; Bancroft, Gregory J

Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients. (2006) Haralambous, Elene; Dolly, Saoirse O; Hibberd, Martin L; Litt, David J; Udalova, Irina A; O'dwyer, Cliona; Langford, Paul R; Simon Kroll, J; Levin, Michael

Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori. (2006) Hatzifoti, Caterina; Roussel, Yvonne; Harris, Andrew G; Wren, Brendan W; Morrow, John W; Bajaj-Elliott, Mona

Artemisone--a highly active antimalarial drug of the artemisinin class. (2006) Haynes, Richard K; Fugmann, Burkhard; Stetter, Jörg; Rieckmann, Karl; Heilmann, Hans-Dietrich; Chan, Ho-Wai; Cheung, Man-Ki; Lam, Wai-Lun; Wong, Ho-Ning; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Peters, Wallace; Robinson, Brian L; Edstein, Michael D; Kotecka, Barbara; Kyle, Dennis E; Beckermann, Bernhard; Gerisch, Michael; Radtke, Martin; Schmuck, Gabriele; Steinke, Wolfram; Wollborn, Ute; Schmeer, Karl; Römer, Axel

Is a helminth always the same as a helminth? (2006) Helmby, H

Immune modulation by helminth infections. (2006) Helmby, Helena; Bickle, Quentin

The frequency of Chlamydia trachomatis major outer membrane protein-specific CD8+ T lymphocytes in active trachoma is associated with current ocular infection. (2006) Holland, Martin J; Faal, Nkoyo; Sarr, Isatou; Joof, Hassan; Laye, Mass; Cameron, Ewen; Pemberton-Pigott, Frederick; Dockrell, Hazel M; Bailey, Robin L; Mabey, David CW

Application of comparative phylogenomics to study the evolution of Yersinia enterocolitica and to identify genetic differences relating to pathogenicity. (2006) Howard, Sarah L; Gaunt, Michael W; Hinds, Jason; Witney, Adam A; Stabler, Richard; Wren, Brendan W

Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. (2006) Hudock, Michael P; Sanz-Rodríguez, CE; Song, Yongcheng; Chan, Julian MW; Zhang, Yonghui; Odeh, Sarah; Kosztowski, Thomas; Leon-Rossell, Annette; Concepción, JL; Yardley, Vanessa; Croft, Simon L; Urbina, Julio A; Oldfield, Eric

Early clinical trials with a new tuberculosis vaccine, MVA85A, in tuberculosis-endemic countries: issues in study design. (2006) Ibanga, Hannah B; Brookes, Roger H; Hill, Philip C; Owiafe, Patrick K; Fletcher, Helen A; Lienhardt, Christian; Hill, Adrian VS; Adegbola, Richard A; McShane, Helen

Biofilm formation in Campylobacter jejuni. (2006) Joshua, GWP; Guthrie-Irons, C; Karlyshev, AV; Wren, BW

The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytes. (2006) Jung, Saet-Byel; Yang, Chul-Su; Lee, Ji-Sook; Shin, A-Rum; Jung, Sung-Soo; Son, Ji Woong; Harding, Clifford V; Kim, Hwa-Jung; Park, Jeong-Kyu; Paik, Tae-Hyun; Song, Chang-Hwa; Jo, Eun-Kyeong

Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens. (2006) Keays, David A; Clark, Taane G; Flint, Jonathan

Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage. (2006) Kelly, John M; McRobert, Louisa; Baker, David A

Quantifying behavioural interactions between humans and mosquitoes: evaluating the protective efficacy of insecticidal nets against malaria transmission in rural Tanzania. (2006) Killeen, Gerry F; Kihonda, Japhet; Lyimo, Edith; Oketch, Fred R; Kotas, Maya E; Mathenge, Evan; Schellenberg, Joanna A; Lengeler, Christian; Smith, Thomas A; Drakeley, Chris J

CD11b regulates recruitment of alveolar macrophages but not pulmonary dendritic cells after pneumococcal challenge. (2006) Kirby, Alun C; Raynes, John G; Kaye, Paul M

Entomological evaluation of malaria vectors at different altitudes in Hai district, northeastern Tanzania. (2006) Kulkarni, MA; Kweka, E; Nyale, E; Lyatuu, E; Mosha, FW; Chandramohan, D; Rau, ME; Drakeley, C

Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method. (2006) Kulkarni, Manisha A; Rowland, Mark; Alifrangis, Michael; Mosha, Frank W; Matowo, Johnson; Malima, Robert; Peter, Justin; Kweka, Eliningaya; Lyimo, Issa; Magesa, Stephen; Salanti, Ali; Rau, Manfred E; Drakeley, Chris

Epidemiological dynamics of antimonial resistance in Leishmania donovani: genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal. (2006) Laurent, Thierry; Rijal, Suman; Yardley, Vanessa; Croft, Simon; De Doncker, Simonne; Decuypere, Saskia; Khanal, Basudha; Singh, Rupa; Schönian, Gabriele; Kuhls, Katrin; Chappuis, François; Dujardin, Jean-Claude

Ex vivo responses for interferon-gamma and proinflammatory cytokine secretion to low-molecular-weight antigen MTB12 of Mycobacterium tuberculosis during human tuberculosis. (2006) Lee, J-S; Son, JW; Jung, S-B; Kwon, Y-M; Yang, C-S; Oh, J-H; Song, C-H; Kim, H-J; Park, J-K; Paik, T-H; Jo, E-K

Early Dengue infection and outcome study (EDEN) - study design and preliminary findings. (2006) Low, Jenny GH; Ooi, Eng-Eong; Tolfvenstam, Thomas; Leo, Yee-Sin; Hibberd, Martin L; Ng, Lee-Ching; Lai, Yee-Ling; Yap, Grace SL; Li, Chenny SC; Vasudevan, Subhash G; Ong, Adrian

Specific binding of Bluetongue virus NS2 to different viral plus-strand RNAs. (2006) Lymperopoulos, Kostas; Noad, Rob; Tosi, Sara; Nethisinghe, Suran; Brierley, Ian; Roy, Polly

The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology. (2006) MacRae, James I; Obado, Samson O; Turnock, Daniel C; Roper, Janine R; Kierans, Martin; Kelly, John M; Ferguson, Michael AJ

Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania. (2006) Mauricio, Isabel L; Gaunt, Michael W; Stothard, J Russell; Miles, Michael A

Towards multilocus sequence typing of the Leishmania donovani complex: resolving genotypes and haplotypes for five polymorphic metabolic enzymes (ASAT, GPI, NH1, NH2, PGD). (2006) Mauricio, Isabel L; Yeo, Matthew; Baghaei, Mehdi; Doto, Daniela; Pratlong, Francine; Zemanova, Eva; Dedet, Jean-Pierre; Lukes, Julius; Miles, Michael A

C-reactive protein initiates transformation of Leishmania donovani and L. mexicana through binding to lipophosphoglycan. (2006) Mbuchi, Margaret; Bates, Paul A; Ilg, Thomas; Coe, John E; Raynes, John G

A conserved subtilisin protease identified in Babesia divergens merozoites. (2006) Montero, Estrella; Gonzalez, Luis Miguel; Rodriguez, Marilis; Oksov, Yelena; Blackman, Michael J; Lobo, Cheryl A

Association of the NRG1 gene and schizophrenia: a meta-analysis. (2006) Munafò, MR; Thiselton, DL; Clark, TG; Flint, J

Neuroticism mediates the association of the serotonin transporter gene with lifetime major depression. (2006) Munafò, Marcus R; Clark, Taane G; Roberts, Kate H; Johnstone, Elaine C

Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline gamma- and delta-lactams via a 'catch and release' protocol. (2006) Musonda, Chitalu C; Gut, Jiri; Rosenthal, Philip J; Yardley, Vanessa; Carvalho de Souza, Renata C; Chibale, Kelly

Defining the origin of Plasmodium falciparum resistant dhfr isolates in Senegal. (2006) Ndiaye, D; Daily, JP; Sarr, O; Ndir, O; Gaye, O; Mboup, S; Roper, C; Wirth, DF

Expression of Plasmodium falciparum genes involved in erythrocyte invasion varies among isolates cultured directly from patients. (2006) Nery, Susana; Deans, Anne-Marie; Mosobo, Moses; Marsh, Kevin; Rowe, J Alexandra; Conway, David J

Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. (2006) Newman, Kirsty C; Korbel, Daniel S; Hafalla, Julius C; Riley, Eleanor M

Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite. (2006) O'Donnell, Rebecca A; Hackett, Fiona; Howell, Steven A; Treeck, Moritz; Struck, Nicole; Krnajski, Zita; Withers-Martinez, Chrislaine; Gilberger, Tim W; Blackman, Michael J

Spatial and temporal variation in malaria transmission in a low endemicity area in northern Tanzania. (2006) Oesterholt, MJAM; Bousema, JT; Mwerinde, OK; Harris, C; Lushino, P; Masokoto, A; Mwerinde, H; Mosha, FW; Drakeley, CJ picture_as_pdf

Numerical analysis of DNA microarray data of Campylobacter jejuni strains correlated with survival, cytolethal distending toxin and haemolysin analyses. (2006) On, Stephen LW; Dorrell, Nick; Petersen, Lise; Bang, Dang D; Morris, Samantha; Forsythe, Stephen J; Wren, Brendan W

Immunoglobulin G antibodies to merozoite surface antigens are associated with recovery from chloroquine-resistant Plasmodium falciparum in Gambian children. (2006) Pinder, Margaret; Sutherland, Colin J; Sisay-Joof, Fatoumatta; Ismaili, Jamila; McCall, Matthew BB; Ord, Rosalyn; Hallett, Rachel; Holder, Anthony A; Milligan, Paul

High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya. (2006) Polley, Spencer D; Conway, David J; Cavanagh, David R; McBride, Jana S; Lowe, Brett S; Williams, Thomas N; Mwangi, Tabitha W; Marsh, Kevin

Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. (2006) Pérez-Victoria, F Javier; Sánchez-Cañete, María P; Seifert, Karin; Croft, Simon L; Sundar, Shyam; Castanys, Santiago; Gamarro, Francisco

The contribution of microscopy to targeting antimalarial treatment in a low transmission area of Tanzania. (2006) Reyburn, Hugh; Ruanda, John; Mwerinde, Ombeni; Drakeley, Chris

Critical role of type 1 cytokines in controlling initial infection with Burkholderia mallei. (2006) Rowland, Caroline A; Lertmemongkolchai, Ganjana; Bancroft, Alison; Haque, Ashraful; Lever, M Stephen; Griffin, Kate F; Jackson, Matthew C; Nelson, Michelle; O'Garra, Anne; Grencis, Richard; Bancroft, Gregory J; Lukaszewski, Roman A

Current issues for anti-malarial drugs to control P. falciparum malaria. (2006) Schellenberg, D; Abdulla, S; Roper, C

DNA barcoding of blastocystis. (2006) Scicluna, Stephanie M; Tawari, Blessing; Clark, C Graham

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. (2006) Sebaihia, Mohammed; Wren, Brendan W; Mullany, Peter; Fairweather, Neil F; Minton, Nigel; Stabler, Richard; Thomson, Nicholas R; Roberts, Adam P; Cerdeño-Tárraga, Ana M; Wang, Hongmei; Holden, Matthew TG; Wright, Anne; Churcher, Carol; Quail, Michael A; Baker, Stephen; Bason, Nathalie; Brooks, Karen; Chillingworth, Tracey; Cronin, Ann; Davis, Paul; Dowd, Linda; Fraser, Audrey; Feltwell, Theresa; Hance, Zahra; Holroyd, Simon; Jagels, Kay; Moule, Sharon; Mungall, Karen; Price, Claire; Rabbinowitsch, Ester; Sharp, Sarah; Simmonds, Mark; Stevens, Kim; Unwin, Louise; Whithead, Sally; Dupuy, Bruno; Dougan, Gordon; Barrell, Bart; Parkhill, Julian

In vitro and in vivo interactions between miltefosine and other antileishmanial drugs. (2006) Seifert, Karin; Croft, Simon L

Serum amyloid A is an innate immune opsonin for Gram-negative bacteria. (2006) Shah, Chandrabala; Hari-Dass, Ranjeeta; Raynes, John G

Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes. (2006) Sharp, Sarah; Lavstsen, Thomas; Fivelman, Quinton L; Saeed, Maha; McRobert, Louisa; Templeton, Thomas J; Jensen, Anja TR; Baker, David A; Theander, Thor G; Sutherland, Colin J

Mycobacterium tuberculosis HBHA protein reacts strongly with the serum immunoglobulin M of tuberculosis patients. (2006) Shin, A-Rum; Lee, Kil-Soo; Lee, Ji-Sook; Kim, Su-Young; Song, Chang-Hwa; Jung, Saet-Byel; Yang, Chul-Su; Jo, Eun-Kyeong; Park, Jeong-Kyu; Paik, Tae-Hyun; Kim, Hwa-Jung

Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. (2006) Stabler, RA; Gerding, DN; Songer, JG; Drudy, D; Brazier, JS; Trinh, HT; Witney, AA; Hinds, J; Wren, BW

The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as virulence genes: response. (2006) Stabler, Richard; Hinds, Jason

Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes. (2006) Swarthout, TD; van den Broek, IV; Kayembe, G; Montgomery, J; Pota, H; Roper, C

Antituberculotic and antiprotozoal activities of primin, a natural benzoquinone: in vitro and in vivo studies. (2006) Tasdemir, Deniz; Brun, Reto; Yardley, Vanessa; Franzblau, Scott G; Rüedi, Peter

Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. (2006) Tasdemir, Deniz; Kaiser, Marcel; Brun, Reto; Yardley, Vanessa; Schmidt, Thomas J; Tosun, Fatma; Rüedi, Peter

pTcINDEX: a stable tetracycline-regulated expression vector for Trypanosoma cruzi. (2006) Taylor, Martin C; Kelly, John M

The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. (2006) Thomson, Nicholas R; Howard, Sarah; Wren, Brendan W; Holden, Matthew TG; Crossman, Lisa; Challis, Gregory L; Churcher, Carol; Mungall, Karen; Brooks, Karen; Chillingworth, Tracey; Feltwell, Theresa; Abdellah, Zahra; Hauser, Heidi; Jagels, Kay; Maddison, Mark; Moule, Sharon; Sanders, Mandy; Whitehead, Sally; Quail, Michael A; Dougan, Gordon; Parkhill, Julian; Prentice, Michael B

Target antigen, age, and duration of antigen exposure independently regulate immunoglobulin G subclass switching in malaria. (2006) Tongren, J Eric; Drakeley, Christopher J; McDonald, Suzanna LR; Reyburn, Hugh G; Manjurano, Alphaxard; Nkya, Watoky MM; Lemnge, Martha M; Gowda, Channe D; Todd, Jim E; Corran, Patrick H; Riley, Eleanor M

Contrasting signatures of selection on the Plasmodium falciparum erythrocyte binding antigen gene family. (2006) Verra, Federica; Chokejindachai, Watcharee; Weedall, Gareth D; Polley, Spencer D; Mwangi, Tabitha W; Marsh, Kevin; Conway, David J

TGF-beta1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria. (2006) Wassmer, Samuel C; de Souza, J Brian; Frère, Corinne; Candal, Francisco J; Juhan-Vague, Irène; Grau, Georges E

The influence of previous exposure to environmental mycobacteria on the interferon-gamma response to bacille Calmette-Guérin vaccination in southern England and northern Malawi. (2006) Weir, RE; Black, GF; Nazareth, B; Floyd, S; Stenson, S; Stanley, C; Branson, K; Sichali, L; Chaguluka, SD; Donovan, L; Crampin, AC; Fine, PEM; Dockrell, HM

Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei. (2006) Wilkinson, Shane R; Prathalingam, S Radhika; Taylor, Martin C; Ahmed, Aiyaz; Horn, David; Kelly, John M

Internal transcribed spacer dimorphism and diversity in Dientamoeba fragilis. (2006) Windsor, Jeffrey J; Macfarlane, Lorna; Clark, C Graham

Nonstructural protein 3 of bluetongue virus assists virus release by recruiting ESCRT-I protein Tsg101. (2006) Wirblich, Christoph; Bhattacharya, Bishnupriya; Roy, Polly

Clostridium difficile comes of age. (2006) Wren, Brendan W

Differential regulation of interleukin-12 and tumour necrosis factor-alpha by phosphatidylinositol 3-kinase and ERK 1/2 pathways during Mycobacterium tuberculosis infection. (2006) Yang, C-S; Lee, J-S; Jung, S-B; Oh, J-H; Song, C-H; Kim, H-J; Park, J-K; Paik, T-H; Jo, E-K

Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-induced IL-23 expression in human macrophages. (2006) Yang, Chul-Su; Song, Chang-Hwa; Lee, Ji-Sook; Jung, Saet-Byel; Oh, Jae-Hee; Park, Jongsun; Kim, Hwa-Jung; Park, Jeong-Kyu; Paik, Tae-Hyun; Jo, Eun-Kyeong

American tegumentary leishmaniasis: Is antimonial treatment outcome related to parasite drug susceptibility? (2006) Yardley, Vanessa; Ortuno, Nimer; Llanos-Cuentas, Alejandro; Chappuis, Francois; Doncker, Simonne De; Ramirez, Luis; Croft, Simon; Arevalo, Jorge; Adaui, Vanessa; Bermudez, Hernan; Decuypere, Saskia; Dujardin, Jean-Claude

Conformer generation under restraints. (2006) de Bakker, Paul IW; Furnham, Nicholas; Blundell, Tom L; DePristo, Mark A