Items where Faculty or Department is "GM-Vaccinology Theme"

LSHTM Organisational Structure (57264)

MRC Gambia (1248)

GM-Vaccinology Theme (328) Month Authors/Creators Item Type Full Text

Article

Comparing accuracy of lipoarabinomannan urine tests for diagnosis of pulmonary tuberculosis in children from four African countries: a cross-sectional study. (2020) Nkereuwem, Esin; Togun, Toyin; Gomez, Marie P; Székely, Rita; Macé, Aurélien; Jobe, Dawda; Schumacher, Samuel G; Kampmann, Beate; Denkinger, Claudia M; Reach4KidsAfrica (R4KA) Consortium

Genomic diversity of Escherichia coli isolates from backyard chickens and guinea fowl in the Gambia. (2020) Foster-Nyarko, Ebenezer; Alikhan, Nabil-Fareed; Ravi, Anuradha; Thomson, Nicholas M; Jarju, Sheikh; Kwambana-Adams, Brenda A; Secka, Arss; O'Grady, Justin; Antonio, Martin; Pallen, Mark John

Population genetic analysis of the Plasmodium falciparum circumsporozoite protein in two distinct ecological regions in Ghana. (2020) Amegashie, Elikplim A; Amenga-Etego, Lucas; Adobor, Courage; Ogoti, Peter; Mbogo, Kevin; Amambua-Ngwa, Alfred; Ghansah, Anita

Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria. (2020) Tola, Monday; Ajibola, Olumide; Idowu, Emmanuel Taiwo; Omidiji, Olusesan; Awolola, Samson Taiwo; Amambua-Ngwa, Alfred

Seroprevalence and Parasite Rates of Plasmodium malariae in a High Malaria Transmission Setting of Southern Nigeria. (2020) Oriero, Eniyou C; Olukosi, Adeola Y; Oduwole, Olabisi A; Djimde, Abdoulaye; D'Alessandro, Umberto; Meremikwu, Martin M; Amambua-Ngwa, Alfred

COVID-19 in Nigeria: Implications for Management of Related Co-morbidities, Prevalent Public Health Challenges, and Future Epidemic Preparedness. (2020) Ola, Bolanle Adeyemi; Nkereuwem, Esin; Oriero, Eniyou; Okomo, Uduak; Afolabi, Muhammed; Togun, Toyin

Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism. (2020) Chaguza, Chrispin; Yang, Marie; Cornick, Jennifer E; du Plessis, Mignon; Gladstone, Rebecca A; Kwambana-Adams, Brenda A; Lo, Stephanie W; Ebruke, Chinelo; Tonkin-Hill, Gerry; Peno, Chikondi; Senghore, Madikay; Obaro, Stephen K; Ousmane, Sani; Pluschke, Gerd; Collard, Jean-Marc; Sigaùque, Betuel; French, Neil; Klugman, Keith P; Heyderman, Robert S; McGee, Lesley; Antonio, Martin; Breiman, Robert F; von Gottberg, Anne; Everett, Dean B; Kadioglu, Aras; Bentley, Stephen D

Tolerance of Gambian Plasmodium falciparum to Dihydroartemisinin and Lumefantrine Detected by Ex Vivo Parasite Survival Rate Assay. (2020) Mbye, Haddijatou; Bojang, Fatoumata; Jawara, Aminata Seedy; Njie, Bekai; Mohammed, Nuredin Ibrahim; Okebe, Joseph; D'Alessandro, Umberto; Amambua-Ngwa, Alfred

Translation of genomic epidemiology of infectious pathogens: Enhancing African genomics hubs for outbreaks. (2020) Oboh, Mary Aigbiremo; Omoleke, Semeeh Akinwale; Ajibola, Olumide; Manneh, Jarra; Kanteh, Abdoulie; Sesay, Abdul-Karim; Amambua-Ngwa, Alfred

Delay in the diagnosis of pulmonary tuberculosis in The Gambia, West Africa: A cross-sectional study. (2020) Owolabi, Olumuyiwa A; Jallow, Alpha O; Jallow, Momodou; Sowe, Gambia; Jallow, Rohey; Genekah, Monica D; Donkor, Simon; Wurrie, Alieu; Kampmann, Beate; Sutherland, Jayne; Togun, Toyin

Genomic diversity of Escherichia coli isolates from non-human primates in the Gambia. (2020) Foster-Nyarko, Ebenezer; Alikhan, Nabil-Fareed; Ravi, Anuradha; Thilliez, Gaëtan; Thomson, Nicholas M; Baker, David; Kay, Gemma; Cramer, Jennifer D; O'Grady, Justin; Antonio, Martin; Pallen, Mark J

Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials. (2020) Mahindra, Amit; Janha, Omar; Mapesa, Kopano; Sanchez-Azqueta, Ana; Alam, Mahmood M; Amambua-Ngwa, Alfred; Nwakanma, Davis C; Tobin, Andrew B; Jamieson, Andrew G

Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers. (2020) Vickers, Molly A; Darboe, Fatoumatta; Muefong, Caleb N; Mbayo, Georgetta; Barry, Amadou; Gindeh, Awa; Njie, Sainabou; Riley, Abi-Janet; Sarr, Binta; Sambou, Basil; Dockrell, Hazel M; Charalambous, Salome; Rachow, Andrea; Owolabi, Olumuyiwa; Jayasooriya, Shamanthi; Sutherland, Jayne S

Mycobacterium tuberculosis-specific plasmablast levels are differentially modulated in tuberculosis infection and disease. (2020) Gindeh, Awa; Owolabi, Olumuyiwa; Donkor, Simon; Sutherland, Jayne S

Insecticide resistance in indoor and outdoor-resting Anopheles gambiae in Northern Ghana. (2020) Hamid-Adiamoh, Majidah; Amambua-Ngwa, Alfred; Nwakanma, Davis; D'Alessandro, Umberto; Awandare, Gordon A; Afrane, Yaw A

The biology of unconventional invasion of Duffy-negative reticulocytes by Plasmodium vivax and its implication in malaria epidemiology and public health. (2020) Golassa, Lemu; Amenga-Etego, Lucas; Lo, Eugenia; Amambua-Ngwa, Alfred

Beyond SARS-CoV-2: Lessons That African Governments Can Apply in Preparation for Possible Future Epidemics. (2020) Oboh, Mary Aigbiremo; Omoleke, Semeeh Akinwale; Imafidon, Christian Eseigbe; Ajibola, Olumide; Oriero, Eniyou Cheryll; Amambua-Ngwa, Alfred

The Etiology of Pneumonia From Analysis of Lung Aspirate and Pleural Fluid Samples: Findings From the Pneumonia Etiology Research for Child Health (PERCH) Study. (2020) Ebruke, Bernard E; Deloria Knoll, Maria; Haddix, Meredith; Zaman, Syed MA; Prosperi, Christine; Feikin, Daniel R; Hammitt, Laura L; Levine, Orin S; O'Brien, Katherine L; Murdoch, David R; Brooks, W Abdullah; Scott, J Anthony G; Kotloff, Karen L; Madhi, Shabir A; Thea, Donald M; Baillie, Vicky L; Chisti, Mohammod Jobayer; Dione, Michel; Driscoll, Amanda J; Fancourt, Nicholas; Karron, Ruth A; Le, Tham T; Mohamed, Shebe; Moore, David P; Morpeth, Susan C; Mwaba, John; Mwansa, James; Bin Shahid, Abu Sadat Mohammad Sayeem; Sow, Samba O; Tapia, Milagritos D; Antonio, Martin; Howie, Stephen RC

A three-marker protein biosignature distinguishes tuberculosis from other respiratory diseases in Gambian children. (2020) Togun, Toyin; Hoggart, Clive J; Agbla, Schadrac C; Gomez, Marie P; Egere, Uzochukwu; Sillah, Abdou K; Saidy, Binta; Mendy, Francis; Pai, Madhukar; Kampmann, Beate

Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation. (2020) Chaguza, Chrispin; Senghore, Madikay; Bojang, Ebrima; Gladstone, Rebecca A; Lo, Stephanie W; Tientcheu, Peggy-Estelle; Bancroft, Rowan E; Worwui, Archibald; Foster-Nyarko, Ebenezer; Ceesay, Fatima; Okoi, Catherine; McGee, Lesley; Klugman, Keith P; Breiman, Robert F; Barer, Michael R; Adegbola, Richard A; Antonio, Martin; Bentley, Stephen D; Kwambana-Adams, Brenda A

Use of resuscitation promoting factors to screen for tuberculosis infection in household-exposed children in The Gambia. (2020) van Loon, W; Gomez, MP; Jobe, D; Franken, KLMC; Ottenhoff, THM; Coninx, M; Kestens, L; Sutherland, JS; Kampmann, B; Tientcheu, LD

Pausing the Fight Against Malaria to Combat the COVID-19 Pandemic in Africa: Is the Future of Malaria Bleak? (2020) Nghochuzie, Nora Nganyewo; Olwal, Charles Ochieng'; Udoakang, Aniefiok John; Amenga-Etego, Lucas Naam-Kayagre; Amambua-Ngwa, Alfred

Impact of routine vaccination against Haemophilus influenzae type b in The Gambia: 20 years after its introduction. (2020) Zaman, Syed Ma; Howie, Stephen Rc; Ochoge, Magnus; Secka, Ousman; Bah, Alasana; Baldeh, Ignatius; Sanneh, Bakary; Darboe, Saffiatou; Ceesay, Buntung; Camara, Haddy Bah; Mawas, Fatme; Ndiaye, Malick; Hossain, Ilias; Salaudeen, Rasheed; Bojang, Kalifa; Ceesay, Samba; Sowe, Dawda; Hossain, M Jahangir; Mulholland, Kim; Kwambana-Adams, Brenda A; Okoi, Catherine; Badjie, Siaka; Ceesay, Lamin; Mwenda, Jason M; Cohen, Adam L; Agocs, Mary; Mihigo, Richard; Bottomley, Christian; Antonio, Martin; Mackenzie, Grant A

Neutrophils in Tuberculosis-Associated Inflammation and Lung Pathology. (2020) Muefong, Caleb N; Sutherland, Jayne S

Etiology of Pediatric Meningitis in West Africa Using Molecular Methods in the Era of Conjugate Vaccines against Pneumococcus, Meningococcus, and Haemophilus influenzae Type b. (2020) Kwambana-Adams, Brenda A; Liu, Jie; Okoi, Catherine; Mwenda, Jason M; Mohammed, Nuredin I; Tsolenyanu, Enyonam; Renner, Lorna Awo; Ansong, Daniel; Tagbo, Beckie N; Bashir, Muhammad F; Hama, Mamadou Kourna; Sonko, Mouhamadou A; Gratz, Jean; Worwui, Archibald; Ndow, Peter; Cohen, Adam L; Serhan, Fatima; Mihigo, Richard; Antonio, Martin; Houpt, Eric; Paediatric Bacterial Meningitis Surveillance Network in West Afr

RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response. (2020) Penn-Nicholson, Adam; Mbandi, Stanley Kimbung; Thompson, Ethan; Mendelsohn, Simon C; Suliman, Sara; Chegou, Novel N; Malherbe, Stephanus T; Darboe, Fatoumatta; Erasmus, Mzwandile; Hanekom, Willem A; Bilek, Nicole; Fisher, Michelle; Kaufmann, Stefan HE; Winter, Jill; Murphy, Melissa; Wood, Robin; Morrow, Carl; Van Rhijn, Ildiko; Moody, Branch; Murray, Megan; Andrade, Bruno B; Sterling, Timothy R; Sutherland, Jayne; Naidoo, Kogieleum; Padayatchi, Nesri; Walzl, Gerhard; Hatherill, Mark; Zak, Daniel; Scriba, Thomas J; Adolescent Cohort Study team; GC6-74 Consortium; SATVI Clinical and Laboratory Team; ScreenTB Consortium; AE-TBC Consortium; RePORT Brazil Team; Peruvian Household Contacts Cohort Team; CAPRISA IMPRESS team

Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes. (2020) Togun, Toyin; Kampmann, Beate; Stoker, Neil Graham; Lipman, Marc

Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates. (2020) Gladstone, Rebecca A; Lo, Stephanie W; Goater, Richard; Yeats, Corin; Taylor, Ben; Hadfield, James; Lees, John A; Croucher, Nicholas J; van Tonder, Andries J; Bentley, Leon J; Quah, Fu Xiang; Blaschke, Anne J; Pershing, Nicole L; Byington, Carrie L; Balaji, Veeraraghavan; Hryniewicz, Waleria; Sigauque, Betuel; Ravikumar, KL; Almeida, Samanta Cristine Grassi; Ochoa, Theresa J; Ho, Pak Leung; du Plessis, Mignon; Ndlangisa, Kedibone M; Cornick, Jennifer E; Kwambana-Adams, Brenda; Benisty, Rachel; Nzenze, Susan A; Madhi, Shabir A; Hawkins, Paulina A; Pollard, Andrew J; Everett, Dean B; Antonio, Martin; Dagan, Ron; Klugman, Keith P; von Gottberg, Anne; Metcalf, Benjamin J; Li, Yuan; Beall, Bernard W; McGee, Lesley; Breiman, Robert F; Aanensen, David M; Bentley, Stephen D; The Global Pneumococcal Sequencing Consortium

Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis. (2020) Andreas, Nicholas J; Basu Roy, Robindra; Gomez-Romero, Maria; Horneffer-van der Sluis, Verena; Lewis, Matthew R; Camuzeaux, Stephane SM; Jiménez, Beatriz; Posma, Joram M; Tientcheu, Leopold; Egere, Uzochukwu; Sillah, Abdou; Togun, Toyin; Holmes, Elaine; Kampmann, Beate

Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients. (2020) Lubbers, Rosalie; Sutherland, Jayne S; Goletti, Delia; de Paus, Roelof A; Dijkstra, Douwe J; van Moorsel, Coline HM; Veltkamp, Marcel; Vestjens, Stefan MT; Bos, Willem JW; Petrone, Linda; Malherbe, Stephanus T; Walzl, Gerhard; Gelderman, Kyra A; Groeneveld, Geert H; Geluk, Annemieke; Ottenhoff, Tom HM; Joosten, Simone A; Trouw, Leendert A

COVID-19 pandemic in west Africa. (2020) Martinez-Alvarez, Melisa; Jarde, Alexander; Usuf, Effua; Brotherton, Helen; Bittaye, Mustapha; Samateh, Ahmadou L; Antonio, Martin; Vives-Tomas, Joan; D'Alessandro, Umberto; Roca, Anna

Genomic diversity of <i>Escherichia coli</i> isolates from non-human primates in the Gambia. (2020) Foster-Nyarko, Ebenezer; Alikhan, Nabil-Fareed; Ravi, Anuradha; Thilliez, Gaëtan; Thomson, Nicholas; Baker, David; Kay, Gemma; Cramer, Jennifer D; O’Grady, Justin; Antonio, Martin; Pallen, Mark J

A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa. (2020) Lo, Stephanie W; Gladstone, Rebecca A; van Tonder, Andries J; Du Plessis, Mignon; Cornick, Jennifer E; Hawkins, Paulina A; Madhi, Shabir A; Nzenze, Susan A; Kandasamy, Rama; Ravikumar, KL; Elmdaghri, Naima; Kwambana-Adams, Brenda; Almeida, Samanta Cristine Grassi; Skoczynska, Anna; Egorova, Ekaterina; Titov, Leonid; Saha, Samir K; Paragi, Metka; Everett, Dean B; Antonio, Martin; Klugman, Keith P; Li, Yuan; Metcalf, Benjamin J; Beall, Bernard; McGee, Lesley; Breiman, Robert F; Bentley, Stephen D; von Gottberg, Anne; Global Pneumococcal Sequencing Consortium

Diarrhoeal disease and subsequent risk of death in infants and children residing in low-income and middle-income countries: analysis of the GEMS case-control study and 12-month GEMS-1A follow-on study. (2020) Levine, Myron M; Nasrin, Dilruba; Acácio, Sozinho; Bassat, Quique; Powell, Helen; Tennant, Sharon M; Sow, Samba O; Sur, Dipika; Zaidi, Anita KM; Faruque, Abu SG; Hossain, M Jahangir; Alonso, Pedro L; Breiman, Robert F; O'Reilly, Ciara E; Mintz, Eric D; Omore, Richard; Ochieng, John B; Oundo, Joseph O; Tamboura, Boubou; Sanogo, Doh; Onwuchekwa, Uma; Manna, Byomkesh; Ramamurthy, Thandavarayan; Kanungo, Suman; Ahmed, Shahnawaz; Qureshi, Shahida; Quadri, Farheen; Hossain, Anowar; Das, Sumon K; Antonio, Martin; Saha, Debasish; Mandomando, Inacio; Blackwelder, William C; Farag, Tamer; Wu, Yukun; Houpt, Eric R; Verweiij, Jaco J; Sommerfelt, Halvor; Nataro, James P; Robins-Browne, Roy M; Kotloff, Karen L

Evolution of Mycobacterium tuberculosis complex lineages and their role in an emerging threat of multidrug resistant tuberculosis in Bamako, Mali. (2020) Senghore, Madikay; Diarra, Bassirou; Gehre, Florian; Otu, Jacob; Worwui, Archibald; Muhammad, Abdul Khalie; Kwambana-Adams, Brenda; Kay, Gemma L; Sanogo, Moumine; Baya, Bocar; Orsega, Susan; Doumbia, Seydou; Diallo, Souleymane; de Jong, Bouke C; Pallen, Mark J; Antonio, Martin

Safety and immunogenicity of a novel 10-valent pneumococcal conjugate vaccine candidate in adults, toddlers, and infants in The Gambia-Results of a phase 1/2 randomized, double-blinded, controlled trial. (2020) Clarke, Ed; Bashorun, Adedapo O; Okoye, Michael; Umesi, Ama; Badjie Hydara, Mariama; Adigweme, Ikechukwu; Dhere, Rajeev; Sethna, Vistasp; Kampmann, Beate; Goldblatt, David; Tate, Andi; Weiner, Debra H; Flores, Jorge; Alderson, Mark R; Lamola, Steve

Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension. (2020) Ofori-Anyinam, Boatema; Riley, Abi Janet; Jobarteh, Tijan; Gitteh, Ensa; Sarr, Binta; Faal-Jawara, Tutty Isatou; Rigouts, Leen; Senghore, Madikay; Kehinde, Aderemi; Onyejepu, Nneka; Antonio, Martin; de Jong, Bouke C; Gehre, Florian; Meehan, Conor J

Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria. (2020) Ajibaye, Olusola; Osuntoki, Akinniyi A; Balogun, Emmanuel O; Olukosi, Yetunde A; Iwalokun, Bamidele A; Oyebola, Kolapo M; Hikosaka, Kenji; Watanabe, Yoh-Ichi; Ebiloma, Godwin U; Kita, Kiyoshi; Amambua-Ngwa, Alfred

High prevalence and extended deletions in Plasmodium falciparum hrp2/3 genomic loci in Ethiopia. (2020) Golassa, Lemu; Messele, Alebachew; Amambua-Ngwa, Alfred; Swedberg, Gote