Year Item Type Full Text

Bibliographic data only

Antiplasmodial activities of some Ghanaian plants traditionally used for fever/malaria treatment and of some alkaloids isolated from Pleiocarpa mutica; in vivo antimalarial activity of pleiocarpine. (2001) Addae-Kyereme, J; Croft, SL; Kendrick, H; Wright, CW

Anti-infectives. (2013) Ahmed, A; Ginn, C; Croft, SL; Brocchini, S

Case study for a vaccine against leishmaniasis. (2013) Alvar, Jorge; Croft, Simon L; Kaye, Paul; Khamesipour, Ali; Sundar, Shyam; Reed, Steven G

Antiprotozoal activity guided fractionation of Sclerocarya birrea (A. Rich.) Hochst. (2004) Anao, I; Houghton, P; Croft, S

In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle. (2001) Asres, K; Bucar, F; Knauder, E; Yardley, V; Kendrick, H; Croft, SL

Prediction of anti-plasmodial activity of Artemisia annua extracts: application of 1H NMR spectroscopy and chemometrics. (2004) Bailey, Nigel JC; Wang, Yulan; Sampson, Julia; Davis, Wendy; Whitcombe, Ian; Hylands, Peter J; Croft, Simon L; Holmes, Elaine

Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity. (2003) Bal, Gunther; Van der Veken, Pieter; Antonov, Dimitri; Lambeir, Anne-Marie; Grellier, Philippe; Croft, Simon L; Augustyns, Koen; Haemers, Achiel

Triclosan is minimally effective in rodent malaria models. (2011) Baschong, Werner; Wittlin, Sergio; Inglis, Kirstine A; Fairlamb, Alan H; Croft, Simon L; Kumar, TR Santha; Fidock, David A; Brun, Reto

Miltefosine: issues to be addressed in the future. (2006) Berman, J; Bryceson, ADM; Croft, S; Engel, J; Gutteridge, W; Karbwang, J; Sindermann, H; Soto, J; Sundar, S; Urbina, JA

Metallocene-based antimalarials: an exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity in chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. (2007) Blackie, Margaret AL; Beagley, Paul; Croft, Simon L; Kendrick, Howard; Moss, John R; Chibale, Kelly

Leishmaniasis. (2018) Burza, S; Croft, SL; Boelaert, M

Screening of plant extracts for antiprotozoal and cytotoxic activities. (2003) Camacho, MDR; Phillipson, JD; Croft, SL; Solis, PN; Marshall, SJ; Ghazanfar, SA

Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. (2004) Cameron, Angus; Read, Jon; Tranter, Rebecca; Winter, Victoria J; Sessions, Richard B; Brady, R Leo; Vivas, Livia; Easton, Anna; Kendrick, Howard; Croft, Simon L; Barros, David; Lavandera, Jose Luis; Martin, José Julio; Risco, Felix; García-Ochoa, Silvestre; Gamo, Fracisco Javier; Sanz, Laura; Leon, Luisa; Ruiz, Jose R; Gabarró, Raquel; Mallo, Araceli; Gómez de las Heras, Federico

In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. (2004) Carrico, Dora; Ohkanda, Junko; Kendrick, Howard; Yokoyama, Kohei; Blaskovich, Michelle A; Bucher, Cynthia J; Buckner, Frederick S; Van Voorhis, Wesley C; Chakrabarti, Debopam; Croft, Simon L; Gelb, Michael H; Sebti, Saïd M; Hamilton, Andrew D

Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. (2003) Chauvière, Gérard; Bouteille, Bernard; Enanga, Bertin; de Albuquerque, Cristina; Croft, Simon L; Dumas, Michel; Périé, Jacques

Design, synthesis, and evaluation of taxanes as potential antimalarial agents. (2003) Chen, J; Kuznetsova, L; Chibale, K; Clarkson, C; Smith, P; Croft, SL; Ojima, I

Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. (2001) Chibale, K; Haupt, H; Kendrick, H; Yardley, V; Saravanamuthu, A; Fairlamb, AH; Croft, SL

Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. (2005) Conners, Rebecca; Schambach, Felix; Read, Jon; Cameron, Angus; Sessions, Richard B; Vivas, Livia; Easton, Anna; Croft, Simon L; Brady, R Leo

Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1,2,4-oxadiazoles. (2004) Cottrell, Denise M; Capers, Jeffrey; Salem, Manar M; DeLuca-Fradley, Kate; Croft, Simon L; Werbovetz, Karl A

Monitoring drug resistance in leishmaniasis. (2001) Croft, SL

From natural products to drugs. (2001) Croft, SL

Antiprotozoals. (2003) Croft, SL

Leishmaniasis. (2015) Croft, SL; Buffett, P

Leishmaniasis chemotherapy--challenges and opportunities. (2011) Croft, SL; Olliaro, P

Antiprotozoal agents. (2010) Croft, SL; Seifert, K

Antiprotozoan drugs. (2001) Croft, SL; Sutherland, C

Recent advances in research and control of malaria, leishmaniasis, trypanosomiasis and schistosomiasis. (2003) Croft, SL; Vivas, L; Brooker, S

Antimalarial Chemotherapy: Mechanisms of Action, Resistance and New Directions in Drug Discovery. (2001) Croft, Simon

Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs. (2003) Croft, Simon L; Coombs, Graham H

Antiprotozoal activities of phospholipid analogues. (2003) Croft, Simon L; Seifert, Karin; Duchêne, Michael

Drug resistance in leishmaniasis. (2006) Croft, Simon L; Sundar, Shyam; Fairlamb, Alan H

The Nobel Prize in Medicine 2015: Two drugs that changed global health. (2015) Croft, Simon L; Ward, Steven

Chemotherapy of leishmaniasis. (2002) Croft, Simon L; Yardley, Vanessa

Drug sensitivity of Leishmania species: some unresolved problems. (2002) Croft, Simon L; Yardley, Vanessa; Kendrick, Howard

Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. (2014) Das, Shantanabha; Freier, Anja; Boussoffara, Thouraya; Das, Sushmita; Oswald, Detlef; Losch, Florian O; Selka, Melanie; Sacerdoti-Sierra, Nina; Schönian, Gabriele; Wiesmüller, Karl-Heinz; Seifert, Karin; Schroff, Matthias; Juhls, Christiane; Jaffe, Charles L; Roy, Syamal; Das, Pradeep; Louzir, Hechmi; Croft, Simon L; Modabber, Farrokh; Walden, Peter

QSAR study on the contribution of log P and E(s) to the in vitro antiprotozoal activity of glutathione derivatives. (2001) Daunes, S; D'Silva, C; Kendrick, H; Yardley, V; Croft, SL

Antimalarial and cytotoxic activities of chiral triamines. (2013) Dellai, Afef; Appel, Jon; Bouraoui, Abderrahman; Croft, Simon; Nefzi, Adel

Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas. (2010) Dujardin, Jean-Claude; González-Pacanowska, Dolores; Croft, Simon L; Olesen, Ole F; Späth, Gerald F

Activities of hexadecylphosphocholine (miltefosine), AmBisome, and sodium stibogluconate (Pentostam) against Leishmania donovani in immunodeficient scid mice. (2001) Escobar, P; Yardley, V; Croft, SL

Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. (2002) Escobar, Patricia; Matu, Sangeeta; Marques, Cláudia; Croft, Simon L

Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents. (2008) Fattorusso, Caterina; Campiani, Giuseppe; Kukreja, Gagan; Persico, Marco; Butini, Stefania; Romano, Maria Pia; Altarelli, Maria; Ros, Sindu; Brindisi, Margherita; Savini, Luisa; Novellino, Ettore; Nacci, Vito; Fattorusso, Ernesto; Parapini, Silvia; Basilico, Nicoletta; Taramelli, Donatella; Yardley, Vanessa; Croft, Simon; Borriello, Marianna; Gemma, Sandra

Antimalarial drug discovery: efficacy models for compound screening. (2004) Fidock, David A; Rosenthal, Philip J; Croft, Simon L; Brun, Reto; Nwaka, Solomon

In-vitro and in-vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis. (2006) Garnier, Tracy; Brown, Marc B; Lawrence, M Jayne; Croft, Simon L

Topical treatment for cutaneous leishmaniasis. (2002) Garnier, Tracy; Croft, Simon L

In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs. (2007) Garnier, Tracy; Mäntylä, Antti; Järvinen, Tomi; Lawrence, Jayne; Brown, Marc; Croft, Simon

Topical buparvaquone formulations for the treatment of cutaneous leishmaniasis. (2007) Garnier, Tracy; Mäntylä, Antti; Järvinen, Tomi; Lawrence, M Jayne; Brown, Marc B; Croft, Simon L

Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials. (2009) Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Joshi, Bhupendra P; Kukreja, Gagan; Coccone, Salvatore Sanna; Bernetti, Matteo; Persico, Marco; Nacci, Vito; Fiorini, Isabella; Novellino, Ettore; Taramelli, Donatella; Basilico, Nicoletta; Parapini, Silvia; Yardley, Vanessa; Croft, Simon; Keller-Maerki, Sonja; Rottmann, Matthias; Brun, Reto; Coletta, Massimiliano; Marini, Stefano; Guiso, Giovanna; Caccia, Silvio; Fattorusso, Caterina

Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies. (2008) Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Kukreja, Gagan; Coccone, Salvatore Sanna; Joshi, Bhupendra P; Persico, Marco; Nacci, Vito; Fiorini, Isabella; Novellino, Ettore; Fattorusso, Ernesto; Taglialatela-Scafati, Orazio; Savini, Luisa; Taramelli, Donatella; Basilico, Nicoletta; Parapini, Silvia; Morace, Giulia; Yardley, Vanessa; Croft, Simon; Coletta, Massimiliano; Marini, Stefano; Fattorusso, Caterina

Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. (2004) Ghosh, Subhash; Chan, Julian MW; Lea, Christopher R; Meints, Gary A; Lewis, Jared C; Tovian, Zev S; Flessner, Ryan M; Loftus, Timothy C; Bruchhaus, Iris; Kendrick, Howard; Croft, Simon L; Kemp, Robert G; Kobayashi, Seiki; Nozaki, Tomoyoshi; Oldfield, Eric

Synthesis and characterization of copper(II) complexes of pyridine-2-carboxamidrazones as potent antimalarial agents. (2003) Gokhale, Nikhil H; Padhye, Subhash B; Billington, David C; Rathbone, Daniel L; Croft, Simon L; Kendrick, Howard D; Anson, Christopher E; Powell, Annie K

Transition metal complexes of buparvaquone as potent new antimalarial agents. 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum. (2003) Gokhale, Nikhil H; Padhye, Subhash B; Croft, Simon L; Kendrick, Howard D; Davies, Wendy; Anson, Christopher E; Powell, Annie K

Metalloantimalarials: synthesis, X-ray crystal structure of potent antimalarial copper (II) complex of arylazo-4-hydroxy-1,2-naphthoquinone. (2006) Gokhale, Nikhil H; Shirisha, K; Padhye, Subhash B; Croft, Simon L; Kendrick, Howard D; Mckee, Vickie

Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: chemical library screen and antileishmanial activity. (2004) Grant, Karen M; Dunion, Morag H; Yardley, Vanessa; Skaltsounis, Alexios-Leandros; Marko, Doris; Eisenbrand, Gerhard; Croft, Simon L; Meijer, Laurent; Mottram, Jeremy C

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action. (2006) Gros, Ludovic; Castillo-Acosta, Victor Manuel; Jiménez Jiménez, Carmen; Sealey-Cardona, Marco; Vargas, Sofia; Manuel Estévez, Antonio; Yardley, Vanessa; Rattray, Lauren; Croft, Simon L; Ruiz-Perez, Luis M; Urbina, Julio A; Gilbert, Ian H; González-Pacanowska, Dolores

Evaluation of azasterols as anti-parasitics. (2006) Gros, Ludovic; Lorente, Silvia Orenes; Jimenez, Carmen Jimenez; Yardley, Vanessa; Rattray, Lauren; Wharton, Hayley; Little, Susan; Croft, Simon L; Ruiz-Perez, Luis M; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. (2002) Guerin, Philippe J; Olliaro, Piero; Sundar, Shyam; Boelaert, Marleen; Croft, Simon L; Desjeux, Philippe; Wasunna, Monique K; Bryceson, Anthony DM

A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity. (2009) Guglielmo, Stefano; Bertinaria, Massimo; Rolando, Barbara; Crosetti, Marco; Fruttero, Roberta; Yardley, Vanessa; Croft, Simon L; Gasco, Alberto

Single-use acupuncture needles: scanning electron-microscopy of needle-tips. (2002) Hayhoe, Simon; McCrossan, Maria; Smith, Aden; Ellis, David; Croft, Simon; Mei, Man Fong

Artemisone--a highly active antimalarial drug of the artemisinin class. (2006) Haynes, Richard K; Fugmann, Burkhard; Stetter, Jörg; Rieckmann, Karl; Heilmann, Hans-Dietrich; Chan, Ho-Wai; Cheung, Man-Ki; Lam, Wai-Lun; Wong, Ho-Ning; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Peters, Wallace; Robinson, Brian L; Edstein, Michael D; Kotecka, Barbara; Kyle, Dennis E; Beckermann, Bernhard; Gerisch, Michael; Radtke, Martin; Schmuck, Gabriele; Steinke, Wolfram; Wollborn, Ute; Schmeer, Karl; Römer, Axel

Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity. (2004) Haynes, Richard K; Ho, Wing-Yan; Chan, Ho-Wai; Fugmann, Burkhard; Stetter, Jörg; Croft, Simon L; Vivas, Livia; Peters, Wallace; Robinson, Brian L

Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities. (2007) Haynes, Richard K; Wong, Ho-Ning; Lee, Kin-Wo; Lung, Chung-Man; Shek, Lai Yung; Williams, Ian D; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Wong, Vincent KW; Ko, Ben CB

Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. (2006) Hudock, Michael P; Sanz-Rodríguez, CE; Song, Yongcheng; Chan, Julian MW; Zhang, Yonghui; Odeh, Sarah; Kosztowski, Thomas; Leon-Rossell, Annette; Concepción, JL; Yardley, Vanessa; Croft, Simon L; Urbina, Julio A; Oldfield, Eric

The distribution of nifurtimox across the healthy and trypanosome-infected murine blood-brain and blood-cerebrospinal fluid barriers. (2011) Jeganathan, Sinthujah; Sanderson, Lisa; Dogruel, Murat; Rodgers, Jean; Croft, Simon; Thomas, Sarah A

Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives. (2004) Jung, Mankil; Lee, Kyunghoon; Jung, Hochul; Kendrick, Howard; Yardley, Vanessa; Croft, Simon L

Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid. (2002) Jung, Mankil; Lee, Kyunghoon; Kendrick, Howard; Robinson, Brian L; Croft, Simon L

Natural Products as potential antiparasitic drugs. (2002) Kayser, O; Kiderlen, A; Croft, SL

Natural products as antiparasitic drugs. (2003) Kayser, O; Kiderlen, AF; Croft, SL

Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs. (2003) Kayser, O; Olbrich, C; Croft, SL; Kiderlen, AF

Formulation of amphotericin B as nanosuspension for oral administration. (2003) Kayser, O; Olbrich, C; Yardley, V; Kiderlen, AF; Croft, SL

Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae). (2003) Kayser, Oliver; Kiderlen, Albrecht F; Croft, Simon L

Toxicity and antileishmanial activity of a new stable lipid suspension of amphotericin B. (2003) Larabi, Malika; Yardley, Vanessa; Loiseau, Philippe M; Appel, Martine; Legrand, Philippe; Gulik, Annette; Bories, Christian; Croft, Simon L; Barratt, Gillian

Epidemiological dynamics of antimonial resistance in Leishmania donovani: genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal. (2006) Laurent, Thierry; Rijal, Suman; Yardley, Vanessa; Croft, Simon; De Doncker, Simonne; Decuypere, Saskia; Khanal, Basudha; Singh, Rupa; Schönian, Gabriele; Kuhls, Katrin; Chappuis, François; Dujardin, Jean-Claude

Structure-activity relationships of antileishmanial and antimalarial chalcones. (2003) Liu, Mei; Wilairat, Prapon; Croft, Simon L; Tan, Agnes Lay-Choo; Go, Mei-Lin

Corrigendum to “Structure–activity relationships of antileishmanial and antimalarial chalcones” (Bioorg. Chem. 2003, 11, 2729–2738]. (2004) Liu, Mei; Wilairat, Prapon; Croft, Simon L; Tan, Agnes Lay-Choo; Go, Mei-Lin

Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasitics. (2005) Lorente, Silvia Orenes; Jimenez, Carmen Jimenez; Gros, Ludovic; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; A Urbina, Julio; Ruiz-Perez, Luis M; Pacanowska, Dolores Gonzalez; Gilbert, Ian H

Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis. (2004) Lorente, Silvia Orenes; Rodrigues, Juliany CF; Jiménez Jiménez, Carmen; Joyce-Menekse, Miranda; Rodrigues, Carlos; Croft, Simon L; Yardley, Vanessa; de Luca-Fradley, Kate; Ruiz-Pérez, Luis M; Urbina, Julio; de Souza, Wanderley; González Pacanowska, Dolores; Gilbert, Ian H

In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. (2009) Luna, Katherine Paola; Hernández, Indira Paola; Rueda, César Mauricio; Zorro, María Magdalena; Croft, Simon L; Escobar, Patricia

In vivo monitoring of intracellular ATP levels in Leishmania donovani promastigotes as a rapid method to screen drugs targeting bioenergetic metabolism. (2001) Luque-Ortega, JR; Rivero-Lezcano, OM; Croft, SL; Rivas, L

The relevance of susceptibility tests, breakpoints and markers. (2013) Maes, L; Cos, P; Croft, SL

Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi. (2003) Magaraci, Filippo; Jimenez, Carmen Jimenez; Rodrigues, Carlos; Rodrigues, Juliany CF; Braga, Marina Vianna; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; de Souza, Wanderley; Ruiz-Perez, Luis M; Urbina, Julio; Gonzalez Pacanowska, Dolores; Gilbert, Ian H

Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. (2001) Martin, MB; Grimley, JS; Lewis, JC; Heath, HT; Bailey, BN; Kendrick, H; Yardley, V; Caldera, A; Lira, R; Urbina, JA; Moreno, SN; Docampo, R; Croft, SL; Oldfield, E

Activity of bisphosphonates against Trypanosoma brucei rhodesiense. (2002) Martin, Michael B; Sanders, John M; Kendrick, Howard; de Luca-Fradley, Kate; Lewis, Jared C; Grimley, Joshua S; Van Brussel, Erin M; Olsen, Jeffrey R; Meints, Gary A; Burzynska, Agnieszka; Kafarski, Pawel; Croft, Simon L; Oldfield, Eric

Recent advances in development of amphotericin B formulations for the treatment of visceral leishmaniasis. (2012) Mohamed-Ahmed, Abeer HA; Brocchini, Stephen; Croft, Simon L

Noncovalent complexation of amphotericin-B with Poly(α-glutamic acid). (2013) Mohamed-Ahmed, Abeer HA; Les, Karolina A; Seifert, Karin; Croft, Simon L; Brocchini, Stephen

Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(α-Glutamic Acid) complex. (2013) Mohamed-Ahmed, Abeer HA; Seifert, Karin; Yardley, Vanessa; Burrell-Saward, Hollie; Brocchini, Stephen; Croft, Simon L

Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine. (2002) Muriithi, Mary W; Abraham, W-R; Addae-Kyereme, Jonathan; Scowen, Ian; Croft, Simon L; Gitu, Peter M; Kendrick, Howard; Njagi, ENM; Wright, Colin W

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin. (2001) Murray, PJ; Kranz, M; Ladlow, M; Taylor, S; Berst, F; Holmes, AB; Keavey, KN; Jaxa-Chamiec, A; Seale, PW; Stead, P; Upton, RJ; Croft, SL; Clegg, W; Elsegood, MR

Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone. (2004) Mäntylä, Antti; Garnier, Tracy; Rautio, Jarkko; Nevalainen, Tapio; Vepsälainen, Jouko; Koskinen, Ari; Croft, Simon L; Järvinen, Tomi

Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives. (2004) Mäntylä, Antti; Rautio, Jarkko; Nevalainen, Tapio; Vepsälainen, Jouko; Juvonen, Risto; Kendrick, Howard; Garnier, Tracy; Croft, Simon L; Järvinen, Tomi

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. (2001) Nan, A; Nanayakkara, NP; Walker, LA; Yardley, V; Croft, SL; Ghandehari, H

Targetable water-soluble polymer-drug conjugates for the treatment of visceral leishmaniasis. (2004) Nan, Anjan; Croft, Simon L; Yardley, Vanessa; Ghandehari, Hamidreza

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate. (2008) Nanayakkara, NP Dhammika; Ager, Arba L; Bartlett, Marilyn S; Yardley, Vanessa; Croft, Simon L; Khan, Ikhlas A; McChesney, James D; Walker, Larry A

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichloropheno xy]quinoline succinate. (2008) Nanayakkara, NP; Ager, AL; Bartlett, MS; Yardley, V; Croft, SL; Khan, IA; McChesney, JD; Walker, LA

Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. (2001) Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; Hamilton, AD

Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents. (2004) Ohkanda, Junko; Buckner, Frederick S; Lockman, Jeffrey W; Yokoyama, Kohei; Carrico, Dora; Eastman, Richard; de Luca-Fradley, Kate; Davies, Wendy; Croft, Simon L; Van Voorhis, Wesley C; Gelb, Michael H; Sebti, Saïd M; Hamilton, Andrew D

Bisphosphonates as novel chemotherapeutic agents. (2001) Oldfield, E; Martin, MB; Croft, SL; Rodriguez, N; Montalvetti, A; Bailey, BN; Docampo, R; Urbina, JA; Khan, AA; Slifer, TR; Araujo, FG; Moreno, SNJ

Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action. (2005) Onyeibor, Onyeka; Croft, Simon L; Dodson, Hilary I; Feiz-Haddad, Mohammad; Kendrick, Howard; Millington, Nicola J; Parapini, Silvia; Phillips, Roger M; Seville, Scott; Shnyder, Steven D; Taramelli, Donatella; Wright, Colin W

Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. (2005) Orenes Lorente, Silvia; Gómez, Rosario; Jiménez, Carmen; Cammerer, Simon; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; Ruiz Perez, Luis M; Urbina, Julio; Gonzalez Pacanowska, Dolores; Gilbert, Ian H

Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide. (2005) Parveen, Seheli; Khan, Mohammed OF; Austin, Susan E; Croft, Simon L; Yardley, Vanessa; Rock, Peter; Douglas, Kenneth T

2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase. (2003) Pez, Didier; Leal, Isabel; Zuccotto, Fabio; Boussard, Cyrille; Brun, Reto; Croft, Simon L; Yardley, Vanessa; Ruiz Perez, Luis M; Gonzalez Pacanowska, Dolores; Gilbert, Ian H

Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity. (2012) Peña, Stella; Scarone, Laura; Manta, Eduardo; Stewart, Lindsay; Yardley, Vanessa; Croft, Simon; Serra, Gloria

Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. (2006) Pérez-Victoria, F Javier; Sánchez-Cañete, María P; Seifert, Karin; Croft, Simon L; Sundar, Shyam; Castanys, Santiago; Gamarro, Francisco

Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira. (2003) Ramírez, Irama; Carabot, Alfredo; Meléndez, Pablo; Carmona, Juan; Jimenez, Manuel; Patel, Asmita V; Crabb, Trevor A; Blunden, Gerald; Cary, Peter D; Croft, Simon L; Costa, Manuel

Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. (2001) Ren, H; Grady, S; Gamenara, D; Heinzen, H; Moyna, P; Croft, SL; Kendrick, H; Yardley, V; Moyna, G

Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. (2003) Ren, Hongyu; Grady, Shannon; Banghart, Matthew; Moulthrop, Jason S; Kendrick, Howard; Yardley, Vanessa; Croft, Simon L; Moyna, Guillermo

Antimonial treatment of visceral leishmaniasis: are current in vitro susceptibility assays adequate for prognosis of in vivo therapy outcome? (2007) Rijal, Suman; Yardley, Vanessa; Chappuis, François; Decuypere, Saskia; Khanal, Basudha; Singh, Rupa; Boelaert, Marleen; De Doncker, Simonne; Croft, Simon; Dujardin, Jean-Claude

Mast cells at the host-pathogen interface: host-protection versus immune evasion in leishmaniasis. (2004) Saha, B; Tonkal, AMDJ; Croft, S; Roy, S

2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity. (2001) Salmon-Chemin, L; Buisine, E; Yardley, V; Kohler, S; Debreu, MA; Landry, V; Sergheraert, C; Croft, SL; Krauth-Siegel, RL; Davioud-Charvet, E

Activity of anti-cancer protein kinase inhibitors against Leishmania spp. (2014) Sanderson, Lisa; Yardley, Vanessa; Croft, Simon L

Antiparasitic activities of acridone alkaloids from Swinglea glutinosa (Bl.) Merr. (2009) Santos, Djalma AP dos; Vieira, Paulo C; Silva, M Fátima das GF da; Fernandes, João B; Rattray, Lauren; Croft, Simon L

In vitro and in vivo interactions between miltefosine and other antileishmanial drugs. (2006) Seifert, Karin; Croft, Simon L

In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. (2010) Seifert, Karin; Escobar, Patricia; Croft, Simon L

Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate. (2015) Seifert, Karin; Juhls, Christiane; Salguero, Francisco J; Croft, Simon L

Antileishmanial structure-activity relationships of synthetic phospholipids: in vitro and in vivo activities of selected derivatives. (2007) Seifert, Karin; Lemke, Andreas; Croft, Simon L; Kayser, Oliver

Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). (2003) Seifert, Karin; Matu, Sangeeta; Javier Pérez-Victoria, F; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L

In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani. (2011) Seifert, Karin; Munday, Jane; Syeda, Tahmina; Croft, Simon L

Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. (2007) Seifert, Karin; Pérez-Victoria, F Javier; Stettler, Marianne; Sánchez-Cañete, María P; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L

Miltefosine (Impavido): the first oral treatment against leishmaniasis. (2004) Sindermann, H; Croft, SL; Engel, KR; Bommer, W; Eibl, HJ; Unger, C; Engel, J

Kinetoplastids: related protozoan pathogens, different diseases. (2008) Stuart, Ken; Brun, Reto; Croft, Simon; Fairlamb, Alan; Gürtler, Ricardo E; McKerrow, Jim; Reed, Steve; Tarleton, Rick

Drug permeation and barrier damage in Leishmania-infected mouse skin. (2016) Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. (2007) Vivas, L; Rattray, L; Stewart, LB; Robinson, BL; Fugmann, B; Haynes, RK; Peters, W; Croft, SL

Plasmodium falciparum: stage specific effects of a selective inhibitor of lactate dehydrogenase. (2005) Vivas, Livia; Easton, Anna; Kendrick, Howard; Cameron, Angus; Lavandera, Jose-Luis; Barros, David; de las Heras, Federico Gomez; Brady, R Leo; Croft, Simon L

Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. (2007) Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Bongard, Emily; Robinson, Brian L; Peters, Wallace; Croft, Simon L

Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents. (2001) Wright, CW; Addae-Kyereme, J; Breen, AG; Brown, JE; Cox, MF; Croft, SL; Gökçek, Y; Kendrick, H; Phillips, RM; Pollet, PL

Antiprotozoal activity of sesquiterpenes from Warburgia ugandensis towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. (2008) Wube, AA; Bucar, F; Gibbons, S; Asres, K; Rattray, L; Croft, SL

Antimalarial compounds from Kniphofia foliosa roots. (2005) Wube, Abraham Abebe; Bucar, Franz; Asres, Kaleab; Gibbons, Simon; Rattray, Lauren; Croft, Simon L

Antiprotozoal activity of drimane and coloratane sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. (2010) Wube, Abraham Abebe; Bucar, Franz; Gibbons, Simon; Asres, Kaleab; Rattray, Lauren; Croft, Simon L

China-Africa and China-Asia Collaboration on Schistosomiasis Control: A SWOT Analysis. (2016) Xu, J; Bergquist, R; Qian, YJ; Wang, Q; Yu, Q; Peeling, R; Croft, S; Guo, JG; Zhou, XN

Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine. (2010) Yardley, Vanessa; Gamarro, Francisco; Croft, Simon L

In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. (2002) Yardley, Vanessa; Khan, Anis A; Martin, Michael B; Slifer, Teri R; Araujo, Fausto G; Moreno, Silvia NJ; Docampo, Roberto; Croft, Simon L; Oldfield, Eric

American tegumentary leishmaniasis: Is antimonial treatment outcome related to parasite drug susceptibility? (2006) Yardley, Vanessa; Ortuno, Nimer; Llanos-Cuentas, Alejandro; Chappuis, Francois; Doncker, Simonne De; Ramirez, Luis; Croft, Simon; Arevalo, Jorge; Adaui, Vanessa; Bermudez, Hernan; Decuypere, Saskia; Dujardin, Jean-Claude

Terpenoids from Guarea rhophalocarpa. (2001) del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN

Assessment of the Antiprotozoal Activity of <i>Galphimia </i><i>g</i><i>lauca </i>and the Isolation of New Nor-secofriedelanes and Nor-friedelanes. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Marley, Dereck; Kirby, Geoffrey C; Warhurst, David C

Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Marley, Dereck; Kirby, Geoffrey C; Warhurst, David C

In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Rock, Peter; Marshall, Sarah J; Schiff, Paul L

In vitro antiprotozoal and cytotoxic activities of some alkaloids, quinones, flavonoids, and coumarins. (2004) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Yardley, Vanesa; Solis, Pablo N

Anti-African trypanocidal and antimalarial activity of natural flavonoids, dibenzoylmethanes and synthetic analogues. (2009) dos Santos, Djalma AP; de C Braga, Patricia A; da Silva, M Fátima das GF; Fernandes, João B; Vieira, Paulo C; Magalhães, Aderbal F; Magalhães, Eva G; Marsaioli, Anita J; de S Moraes, Valéria R; Rattray, Lauren; Croft, Simon L

Triterpenic acids and flavonoids from Satureja parvifolia. Evaluation of their antiprotozoal activity. (2006) van Baren, C; Anao, I; Lira, PD; Debenedetti, S; Houghton, P; Croft, S; Martino, V

Public

New Research Institute Combats Infectious Diseases Globally - 16 December 2011. (2011) UNSPECIFIED audio_file

Treatment of localised cutaneous Leishmania tropica infection in Aleppo, Syria and drug sensitivity of clinical isolates. (2010) Abazid, Nizar

Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis. (2018) Ashwin, Helen; Seifert, Karin; Forrester, Sarah; Brown, Najmeeyah; MacDonald, Sandy; James, Sally; Lagos, Dimitris; Timmis, Jon; Mottram, Jeremy C; Croft, Simon L; Kaye, Paul M

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. (2017) Baker, David A; Stewart, Lindsay B; Large, Jonathan M; Bowyer, Paul W; Ansell, Keith H; Jiménez-Díaz, María B; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J; Bouloc, Nathalie S; Coombs, Peter J; Whalley, David; Harding, Denise J; Smiljanic-Hurley, Ela; Wheldon, Mary C; Walker, Eloise M; Dessens, Johannes T; Lafuente, María José; Sanz, Laura M; Gamo, Francisco-Javier; Ferrer, Santiago B; Hui, Raymond; Bousema, Teun; Angulo-Barturén, Iñigo; Merritt, Andy T; Croft, Simon L; Gutteridge, Winston E; Kettleborough, Catherine A; Osborne, Simon A

Emerging paradigms in anti-infective drug design. (2014) Barrett, Michael P; Croft, Simon L

Management of trypanosomiasis and leishmaniasis. (2012) Barrett, Michael P; Croft, Simon L

In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial. (2017) Basilico, Nicoletta; Parapini, Silvia; Sparatore, Anna; Romeo, Sergio; Misiano, Paola; Vivas, Livia; Yardley, Vanessa; Croft, Simon L; Habluetzel, Annette; Lucantoni, Leonardo; Renia, Laurent; Russell, Bruce; Suwanarusk, Rossarin; Nosten, Francois; Dondio, Giulio; Bigogno, Chiara; Jabes, Daniela; Taramelli, Donatella

Development of an imaging model of a CNS infection with African trypanosomes. (2015) Burrell-Saward, H

Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human african trypanosomiasis. (2017) Burrell-Saward, H; Harris, AJ; de LaFlor, R; Sallam, H; Alavijeh, MS; Ward, TH; Croft, SL

A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis. (2014) Burrell-Saward, Hollie; Rodgers, Jean; Bradley, Barbara; Croft, Simon L; Ward, Theresa H

Understanding the transmission dynamics of Leishmania donovani to provide robust evidence for interventions to eliminate visceral leishmaniasis in Bihar, India. (2016) Cameron, Mary M; Acosta-Serrano, Alvaro; Bern, Caryn; Boelaert, Marleen; den Boer, Margriet; Burza, Sakib; Chapman, Lloyd AC; Chaskopoulou, Alexandra; Coleman, Michael; Courtenay, Orin; Croft, Simon; Das, Pradeep; Dilger, Erin; Foster, Geraldine; Garlapati, Rajesh; Haines, Lee; Harris, Angela; Hemingway, Janet; Hollingsworth, T Déirdre; Jervis, Sarah; Medley, Graham; Miles, Michael; Paine, Mark; Picado, Albert; Poché, Richard; Ready, Paul; Rogers, Matthew; Rowland, Mark; Sundar, Shyam; de Vlas, Sake J; Weetman, David

Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis. (2019) Caridha, Diana; Vesely, Brian; van Bocxlaer, Katrien; Arana, Byron; Mowbray, Charles E; Rafati, Sima; Uliana, Silvia; Reguera, Rosa; Kreishman-Deitrick, Mara; Sciotti, Richard; Buffet, Pierre; Croft, Simon L

An efficient and novel technology for the extraction of parasite genomic DNA from whole blood or culture. (2019) Clark, David J; Moore, Catherine M; Flanagan, Marc; Bocxlaer, Katrien Van; Piperaki, Evangelia-Theophano; Yardley, Vanessa; Croft, Simon L; Tyson, John; Whitehouse, Sam P; O'Halloran, Jonathan; Krishna, Sanjeev; Staines, Henry M

Kinetoplastida: new therapeutic strategies. (2008) Croft, SL

Essentials of antimicrobial pharmacology. Ed. P.H. Axelsen. Humana Press, 2001. Pp. 141. $24.50 pb. ISBN 0 896 03842 4. [Book Review]. (2002) Croft, SL

Neglected tropical diseases in the genomics era: re-evaluating the impact of new drugs and mass drug administration. (2016) Croft, Simon L

PKDL--a drug related phenomenon? (2008) Croft, Simon L

Leishmania and other intracellular pathogens: selectivity, drug distribution and PK-PD. (2017) Croft, Simon L

Review of pyronaridine anti-malarial properties and product characteristics. (2012) Croft, Simon L; Duparc, Stephan; Arbe-Barnes, Sarah J; Craft, J Carl; Shin, Chang-Sik; Fleckenstein, Lawrence; Borghini-Fuhrer, Isabelle; Rim, Han-Jong

Current scenario of drug development for leishmaniasis. (2006) Croft, Simon L; Seifert, Karin; Yardley, Vanessa

Antiprotozoal glutathione derivatives with flagellar membrane binding activity against T. brucei rhodesiense. (2016) Daunes, S; Yardley, V; Croft, SL; D'Silva, C

Leishmaniasis: new approaches to disease control. (2003) Davies, Clive R; Kaye, Paul; Croft, Simon L; Sundar, Shyam

Science and surveillance in the visceral leishmaniasis elimination programme in India. (2022) Dial, NJ

Costs and outcomes of active and passive case detection for visceral leishmaniasis (Kala-Azar) to inform elimination strategies in Bihar, India. (2021) Dial, Natalie J; Medley, Graham F; Croft, Simon L; Mahapatra, Tanmay; Priyamvada, Khushbu; Sinha, Bikas; Palmer, Lucy; Terris-Prestholt, Fern

Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis. (2019) Forrester, Sarah; Siefert, Karin; Ashwin, Helen; Brown, Najmeeyah; Zelmar, Andrea; James, Sally; Lagos, Dimitris; Timmis, Jon; Chatterjee, Mitali; Mottram, Jeremy C; Croft, Simon L; Kaye, Paul M

Biomedicine and biotechnology: public health impact. (2014) Ganguly, Nirmal K; Croft, Simon; Singh, Lalji; Sinha, Subrata; Balganesh, Tanjore

Evaluating drug resistance in visceral leishmaniasis: the challenges. (2016) Hendrickx, S; Guerin, PJ; Caljon, G; Croft, SL; Maes, L

Chemical and bioassay techniques to authenticate quality of the anti-leishmanial drug miltefosine. (2015) Kaur, Harparkash; Seifert, Karin; Hawkes, Geoffrey E; Coumbarides, Gregory S; Alvar, Jorge; Croft, Simon L

Leishmaniasis immunopathology-impact on design and use of vaccines, diagnostics and drugs. (2020) Kaye, Paul M; Cruz, Israel; Picado, Albert; Van Bocxlaer, Katrien; Croft, Simon L

Metabolic, immune, and gut microbial signals mount a systems response to Leishmania major infection. (2014) Lamour, Sabrina D; Veselkov, Kirill A; Posma, Joram M; Giraud, Emilie; Rogers, Matthew E; Croft, Simon; Marchesi, Julian R; Holmes, Elaine; Seifert, Karin; Saric, Jasmina

Chitosan Contribution to Therapeutic and Vaccinal Approaches for the Control of Leishmaniasis. (2020) Loiseau, Philippe M; Pomel, Sébastien; Croft, Simon L

Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase. (2013) McLatchie, Alex P; Burrell-Saward, Hollie; Myburgh, Elmarie; Lewis, Michael D; Ward, Theresa H; Mottram, Jeremy C; Croft, Simon L; Kelly, John M; Taylor, Martin C

Development of Novel Predictive 2D and 3D in Vitro Models For Anti-Leishmanial Drug Testing. (2018) O'Keeffe, A

Novel 2D and 3D Assays to Determine the Activity of Anti-Leishmanial Drugs. (2020) O'Keeffe, Alec; Hale, Christine; Cotton, James A; Yardley, Vanessa; Gupta, Kapish; Ananthanarayanan, Abhishek; Murdan, Sudaxshina; Croft, Simon L

Development of an in vitro media perfusion model of Leishmania major macrophage infection. (2019) O'Keeffe, Alec; Hyndman, Lauren; McGinty, Sean; Riezk, Alaa; Murdan, Sudaxshina; Croft, Simon L

Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. (2015) Riede, O; Seifert, K; Oswald, D; Endmann, A; Hock, C; Winkler, A; Salguero, FJ; Schroff, M; Croft, SL; Juhls, C

Insights into the application of chitosan as an anti-leishmanial compound. (2020) Riezk, A

Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicana In Vitro. (2019) Riezk, Alaa; Raynes, John G; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis. (2020) Riezk, Alaa; Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug. (2021) Sanderson, Lisa; da Silva, Marcelo; Sekhar, Gayathri N; Brown, Rachel C; Burrell-Saward, Hollie; Fidanboylu, Mehmet; Liu, Bo; Dailey, Lea Ann; Dreiss, Cécile A; Lorenz, Chris; Christie, Mark; Persaud, Shanta J; Yardley, Vanessa; Croft, Simon L; Valero, Margarita; Thomas, Sarah A

Innovations for the elimination and control of visceral leishmaniasis. (2019) Selvapandiyan, Angamuthu; Croft, Simon L; Rijal, Suman; Nakhasi, Hira L; Ganguly, Nirmal K

A Replicative In Vitro Assay for Drug Discovery against Leishmania donovani. (2016) Tegazzini, Diana; Díaz, Rosario; Aguilar, Fernando; Peña, Imanol; Presa, Jesús L; Yardley, Vanessa; Martin, Julio J; Coteron, Jose M; Croft, Simon L; Cantizani, Juan

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis. (2019) Van Bocxlaer, Katrien; Caridha, Diana; Black, Chad; Vesely, Brian; Leed, Susan; Sciotti, Richard J; Wijnant, Gert-Jan; Yardley, Vanessa; Braillard, Stéphanie; Mowbray, Charles E; Ioset, Jean-Robert; Croft, Simon L

Pharmacokinetics and pharmacodynamics in the treatment of cutaneous leishmaniasis - challenges and opportunities. (2021) Van Bocxlaer, Katrien; Croft, Simon L

Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles. (2018) Van Bocxlaer, Katrien; Gaukel, Eric; Hauser, Deirdre; Park, Seong Hee; Schock, Sara; Yardley, Vanessa; Randolph, Ryan; Plattner, Jacob J; Merchant, Tejal; Croft, Simon L; Jacobs, Robert T; Wring, Stephen A

Film-Forming Systems for the Delivery of DNDI-0690 to Treat Cutaneous Leishmaniasis. (2021) Van Bocxlaer, Katrien; McArthur, Kerri-Nicola; Harris, Andy; Alavijeh, Mo; Braillard, Stéphanie; Mowbray, Charles E; Croft, Simon L

Topical formulations of miltefosine for cutaneous leishmaniasis in a BALB/c mouse model. (2016) Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Treatment of experimental visceral leishmaniasis with single-dose liposomal amphotericin B - pharmacodynamics and biodistribution at different stages of disease. (2017) Voak, AA; Harris, A; Qaiser, Z; Croft, SL; Seifert, K

Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis. (2021) Voak, Andrew A; Harris, Andy; Coteron-Lopez, Jose Miguel; Angulo-Barturen, Iñigo; Ferrer-Bazaga, Santiago; Croft, Simon L; Seifert, Karin

Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages. (2018) Voak, Andrew A; Standing, Joseph F; Sepúlveda, Nuno; Harris, Andy; Croft, Simon L; Seifert, Karin

New pharmacokinetic and PK/PD drug development methodologies for cutaneous leishmaniasis. (2018) Wijnant, GJ

Pharmacokinetics and Pharmacodynamics of the Nitroimidazole DNDI-0690 in Mouse Models of Cutaneous Leishmaniasis. (2019) Wijnant, Gert-Jan; Croft, Simon L; de la Flor, Raul; Alavijeh, Mo; Yardley, Vanessa; Braillard, Stéphanie; Mowbray, Charles; Van Bocxlaer, Katrien

Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B. (2018) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Fortes Francisco, Amanda; Yardley, Vanessa; Harris, Andy; Alavijeh, Mo; Murdan, Sudaxshina; Croft, Simon L

Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome® and AmBisome® in murine cutaneous leishmaniasis. (2018) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Harris, Andy; Alavijeh, Mo; Silva-Pedrosa, Rita; Antunes, Sandra; Mauricio, Isabel; Murdan, Sudaxshina; Croft, Simon L

Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Harris, Andy; Murdan, Sudaxshina; Croft, Simon L

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

The sensitivity of clinical isolates of Leishmania from Peru and Nepal to miltefosine. (2005) Yardley, Vanessa; Croft, Simon L; De Doncker, Simonne; Dujardin, Jean-Claude; Koirala, Siddhartha; Rijal, Suman; Miranda, Cesar; Llanos-Cuentas, Alejandro; Chappuis, Francois

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Antileishmanial and antitrypanosomal drug identification. (2017) Croft, Simon L; Chatelain, Eric; Barrett, Michael P picture_as_pdf

Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria. (2021) Tempone, Andre G; Pieper, Pauline; Borborema, Samanta ET; Thevenard, Fernanda; Lago, Joao Henrique G; Croft, Simon L; Anderson, Edward A picture_as_pdf