Items where Author is "Delves, Michael J"

Year Item Type Full Text

Bibliographic data only

A GFP-actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle. (2011) Angrisano, Fiona; Delves, Michael J; Sturm, Angelika; Mollard, Vanessa; McFadden, Geoffrey I; Sinden, Robert E; Baum, Jake

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria. (2012) Biagini, Giancarlo A; Fisher, Nicholas; Shone, Alison E; Mubaraki, Murad A; Srivastava, Abhishek; Hill, Alisdair; Antoine, Thomas; Warman, Ashley J; Davies, Jill; Pidathala, Chandrakala; Amewu, Richard K; Leung, Suet C; Sharma, Raman; Gibbons, Peter; Hong, David W; Pacorel, Bénédicte; Lawrenson, Alexandre S; Charoensutthivarakul, Sitthivut; Taylor, Lee; Berger, Olivier; Mbekeani, Alison; Stocks, Paul A; Nixon, Gemma L; Chadwick, James; Hemingway, Janet; Delves, Michael J; Sinden, Robert E; Zeeman, Anne-Marie; Kocken, Clemens HM; Berry, Neil G; O'Neill, Paul M; Ward, Stephen A

Assessing transmission blockade in Plasmodium spp. (2013) Blagborough, Andrew M; Delves, Michael J; Ramakrishnan, Chandra; Lal, Kalpana; Butcher, Geoffrey; Sinden, Robert E

Measuring the blockade of malaria transmission--an analysis of the Standard Membrane Feeding Assay. (2012) Churcher, Thomas S; Blagborough, Andrew M; Delves, Michael; Ramakrishnan, Chandra; Kapulu, Melissa C; Williams, Andrew R; Biswas, Sumi; Da, Dari F; Cohuet, Anna; Sinden, Robert E

Plasmodium cell biology should inform strategies used in the development of antimalarial transmission-blocking drugs. (2012) Delves, Michael J

A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines. (2012) Delves, Michael J; Ramakrishnan, Chandra; Blagborough, Andrew M; Leroy, Didier; Wells, Timothy NC; Sinden, Robert E

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs. (2013) Delves, Michael J; Ruecker, Andrea; Straschil, Ursula; Lelièvre, Jöel; Marques, Sara; López-Barragán, María José; Herreros, Esperanza; Sinden, Robert E

Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions. (2016) Delves, Michael J; Straschil, Ursula; Ruecker, Andrea; Miguel-Blanco, Celia; Marques, Sara; Dufour, Alexandre C; Baum, Jake; Sinden, Robert E

Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development. (2008) Lal, Kalpana; Delves, Michael J; Bromley, Elizabeth; Wastling, Jonathan M; Tomley, Fiona M; Sinden, Robert E

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. (2017) Leven, Michael; Knaab, Tanja C; Held, Jana; Duffy, Sandra; Meister, Stephan; Fischli, Christoph; Meitzner, Diane; Lehmann, Ursula; Lungerich, Beate; Kuna, Krystina; Stahlke, Petra; Delves, Michael J; Buchholz, Mirko; Winzeler, Elizabeth A; Avery, Vicky M; Mordmüller, Benjamin; Wittlin, Sergio; Kurz, Thomas

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans. (2014) Malmquist, Nicholas A; Sundriyal, Sandeep; Caron, Joachim; Chen, Patty; Witkowski, Benoit; Menard, Didier; Suwanarusk, Rossarin; Renia, Laurent; Nosten, Francois; Jiménez-Díaz, María Belén; Angulo-Barturen, Iñigo; Santos Martínez, María; Ferrer, Santiago; Sanz, Laura M; Gamo, Francisco-Javier; Wittlin, Sergio; Duffy, Sandra; Avery, Vicky M; Ruecker, Andrea; Delves, Michael J; Sinden, Robert E; Fuchter, Matthew J; Scherf, Artur

Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation. (2015) Miguel-Blanco, Celia; Lelièvre, Joël; Delves, Michael J; Bardera, Ana I; Presa, Jesús L; López-Barragán, María José; Ruecker, Andrea; Marques, Sara; Sinden, Robert E; Herreros, Esperanza

Quinolone-3-diarylethers: a new class of antimalarial drug. (2013) Nilsen, Aaron; LaCrue, Alexis N; White, Karen L; Forquer, Isaac P; Cross, Richard M; Marfurt, Jutta; Mather, Michael W; Delves, Michael J; Shackleford, David M; Saenz, Fabian E; Morrisey, Joanne M; Steuten, Jessica; Mutka, Tina; Li, Yuexin; Wirjanata, Grennady; Ryan, Eileen; Duffy, Sandra; Kelly, Jane Xu; Sebayang, Boni F; Zeeman, Anne-Marie; Noviyanti, Rintis; Sinden, Robert E; Kocken, Clemens HM; Price, Ric N; Avery, Vicky M; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Ferrer, Santiago; Herreros, Esperanza; Sanz, Laura M; Gamo, Francisco-Javier; Bathurst, Ian; Burrows, Jeremy N; Siegl, Peter; Guy, R Kiplin; Winter, Rolf W; Vaidya, Akhil B; Charman, Susan A; Kyle, Dennis E; Manetsch, Roman; Riscoe, Michael K

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. (2016) Paquet, Tanya; Le Manach, Claire; Cabrera, Diego González; Younis, Yassir; Henrich, Philipp P; Abraham, Tara S; Lee, Marcus CS; Basak, Rajshekhar; Ghidelli-Disse, Sonja; Lafuente-Monasterio, María José; Bantscheff, Marcus; Ruecker, Andrea; Blagborough, Andrew M; Zakutansky, Sara E; Zeeman, Anne-Marie; White, Karen L; Shackleford, David M; Mannila, Janne; Morizzi, Julia; Scheurer, Christian; Angulo-Barturen, Iñigo; Martínez, María Santos; Ferrer, Santiago; Sanz, Laura María; Gamo, Francisco Javier; Reader, Janette; Botha, Mariette; Dechering, Koen J; Sauerwein, Robert W; Tungtaeng, Anchalee; Vanachayangkul, Pattaraporn; Lim, Chek Shik; Burrows, Jeremy; Witty, Michael J; Marsh, Kennan C; Bodenreider, Christophe; Rochford, Rosemary; Solapure, Suresh M; Jiménez-Díaz, María Belén; Wittlin, Sergio; Charman, Susan A; Donini, Cristina; Campo, Brice; Birkholtz, Lyn-Marie; Hanson, Kirsten K; Drewes, Gerard; Kocken, Clemens HM; Delves, Michael J; Leroy, Didier; Fidock, David A; Waterson, David; Street, Leslie J; Chibale, Kelly

A Malaria Transmission-Blocking (+)-Usnic Acid Derivative Prevents Plasmodium Zygote-to-Ookinete Maturation in the Mosquito Midgut. (2016) Pastrana-Mena, Rebecca; Mathias, Derrick K; Delves, Michael; Rajaram, Krithika; King, Jonas G; Yee, Rebecca; Trucchi, Beatrice; Verotta, Luisella; Dinglasan, Rhoel R

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. (2015) Phillips, Margaret A; Lotharius, Julie; Marsh, Kennan; White, John; Dayan, Anthony; White, Karen L; Njoroge, Jacqueline W; El Mazouni, Farah; Lao, Yanbin; Kokkonda, Sreekanth; Tomchick, Diana R; Deng, Xiaoyi; Laird, Trevor; Bhatia, Sangeeta N; March, Sandra; Ng, Caroline L; Fidock, David A; Wittlin, Sergio; Lafuente-Monasterio, Maria; Benito, Francisco Javier Gamo; Alonso, Laura Maria Sanz; Martinez, Maria Santos; Jimenez-Diaz, Maria Belen; Bazaga, Santiago Ferrer; Angulo-Barturen, Iñigo; Haselden, John N; Louttit, James; Cui, Yi; Sridhar, Arun; Zeeman, Anna-Marie; Kocken, Clemens; Sauerwein, Robert; Dechering, Koen; Avery, Vicky M; Duffy, Sandra; Delves, Michael; Sinden, Robert; Ruecker, Andrea; Wickham, Kristina S; Rochford, Rosemary; Gahagen, Janet; Iyer, Lalitha; Riccio, Ed; Mirsalis, Jon; Bathhurst, Ian; Rueckle, Thomas; Ding, Xavier; Campo, Brice; Leroy, Didier; Rogers, M John; Rathod, Pradipsinh K; Burrows, Jeremy N; Charman, Susan A

Laboratory maintenance of rodent malaria parasites. (2013) Ramakrishnan, Chandra; Delves, Michael J; Lal, Kalpana; Blagborough, Andrew M; Butcher, Geoffrey; Baker, Kenneth W; Sinden, Robert E

A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs. (2014) Ruecker, A; Mathias, DK; Straschil, U; Churcher, TS; Dinglasan, RR; Leroy, D; Sinden, RE; Delves, MJ

The Plasmodium berghei sexual stage antigen PSOP12 induces anti-malarial transmission blocking immunity both in vivo and in vitro. (2014) Sala, KA; Nishiura, H; Upton, LM; Zakutansky, SE; Delves, MJ; Iyori, M; Mizutani, M; Sinden, RE; Yoshida, S; Blagborough, AM

The design and interpretation of laboratory assays measuring mosquito transmission of Plasmodium. (2012) Sinden, Robert E; Blagborough, Andrew M; Churcher, Thomas; Ramakrishnan, Chandra; Biswas, Sumi; Delves, Michael J

Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle. (2011) Slavic, Ksenija; Delves, Michael J; Prudêncio, Miguel; Talman, Arthur M; Straschil, Ursula; Derbyshire, Elvira T; Xu, Zhengyao; Sinden, Robert E; Mota, Maria M; Morin, Christophe; Tewari, Rita; Krishna, Sanjeev; Staines, Henry M

Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity. (2017) Vanaerschot, Manu; Lucantoni, Leonardo; Li, Tao; Combrinck, Jill M; Ruecker, Andrea; Kumar, TR Santha; Rubiano, Kelly; Ferreira, Pedro E; Siciliano, Giulia; Gulati, Sonia; Henrich, Philipp P; Ng, Caroline L; Murithi, James M; Corey, Victoria C; Duffy, Sandra; Lieberman, Ori J; Veiga, M Isabel; Sinden, Robert E; Alano, Pietro; Delves, Michael J; Lee Sim, Kim; Winzeler, Elizabeth A; Egan, Timothy J; Hoffman, Stephen L; Avery, Vicky M; Fidock, David A

Public

Spatial localisation of actin filaments across developmental stages of the malaria parasite. (2012) Angrisano, Fiona; Riglar, David T; Sturm, Angelika; Volz, Jennifer C; Delves, Michael J; Zuccala, Elizabeth S; Turnbull, Lynne; Dekiwadia, Chaitali; Olshina, Maya A; Marapana, Danushka S; Wong, Wilson; Mollard, Vanessa; Bradin, Clare H; Tonkin, Christopher J; Gunning, Peter W; Ralph, Stuart A; Whitchurch, Cynthia B; Sinden, Robert E; Cowman, Alan F; McFadden, Geoffrey I; Baum, Jake

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. (2019) Baragaña, Beatriz; Forte, Barbara; Choi, Ryan; Nakazawa Hewitt, Stephen; Bueren-Calabuig, Juan A; Pisco, João Pedro; Peet, Caroline; Dranow, David M; Robinson, David A; Jansen, Chimed; Norcross, Neil R; Vinayak, Sumiti; Anderson, Mark; Brooks, Carrie F; Cooper, Caitlin A; Damerow, Sebastian; Delves, Michael; Dowers, Karen; Duffy, James; Edwards, Thomas E; Hallyburton, Irene; Horst, Benjamin G; Hulverson, Matthew A; Ferguson, Liam; Jiménez-Díaz, María Belén; Jumani, Rajiv S; Lorimer, Donald D; Love, Melissa S; Maher, Steven; Matthews, Holly; McNamara, Case W; Miller, Peter; O'Neill, Sandra; Ojo, Kayode K; Osuna-Cabello, Maria; Pinto, Erika; Post, John; Riley, Jennifer; Rottmann, Matthias; Sanz, Laura M; Scullion, Paul; Sharma, Arvind; Shepherd, Sharon M; Shishikura, Yoko; Simeons, Frederick RC; Stebbins, Erin E; Stojanovski, Laste; Straschil, Ursula; Tamaki, Fabio K; Tamjar, Jevgenia; Torrie, Leah S; Vantaux, Amélie; Witkowski, Benoît; Wittlin, Sergio; Yogavel, Manickam; Zuccotto, Fabio; Angulo-Barturen, Iñigo; Sinden, Robert; Baum, Jake; Gamo, Francisco-Javier; Mäser, Pascal; Kyle, Dennis E; Winzeler, Elizabeth A; Myler, Peter J; Wyatt, Paul G; Floyd, David; Matthews, David; Sharma, Amit; Striepen, Boris; Huston, Christopher D; Gray, David W; Fairlamb, Alan H; Pisliakov, Andrei V; Walpole, Chris; Read, Kevin D; Van Voorhis, Wesley C; Gilbert, Ian H

A novel multiple-stage antimalarial agent that inhibits protein synthesis. (2015) Baragaña, Beatriz; Hallyburton, Irene; Lee, Marcus CS; Norcross, Neil R; Grimaldi, Raffaella; Otto, Thomas D; Proto, William R; Blagborough, Andrew M; Meister, Stephan; Wirjanata, Grennady; Ruecker, Andrea; Upton, Leanna M; Abraham, Tara S; Almeida, Mariana J; Pradhan, Anupam; Porzelle, Achim; Luksch, Torsten; Martínez, María Santos; Luksch, Torsten; Bolscher, Judith M; Woodland, Andrew; Norval, Suzanne; Zuccotto, Fabio; Thomas, John; Simeons, Frederick; Stojanovski, Laste; Osuna-Cabello, Maria; Brock, Paddy M; Churcher, Tom S; Sala, Katarzyna A; Zakutansky, Sara E; Jiménez-Díaz, María Belén; Sanz, Laura Maria; Riley, Jennifer; Basak, Rajshekhar; Campbell, Michael; Avery, Vicky M; Sauerwein, Robert W; Dechering, Koen J; Noviyanti, Rintis; Campo, Brice; Frearson, Julie A; Angulo-Barturen, Iñigo; Ferrer-Bazaga, Santiago; Gamo, Francisco Javier; Wyatt, Paul G; Leroy, Didier; Siegl, Peter; Delves, Michael J; Kyle, Dennis E; Wittlin, Sergio; Marfurt, Jutta; Price, Ric N; Sinden, Robert E; Winzeler, Elizabeth A; Charman, Susan A; Bebrevska, Lidiya; Gray, David W; Campbell, Simon; Fairlamb, Alan H; Willis, Paul A; Rayner, Julian C; Fidock, David A; Read, Kevin D; Gilbert, Ian H

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy. (2016) Baragaña, Beatriz; Norcross, Neil R; Wilson, Caroline; Porzelle, Achim; Hallyburton, Irene; Grimaldi, Raffaella; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Stojanovski, Laste; Simeons, Frederick RC; Wyatt, Paul G; Delves, Michael J; Meister, Stephan; Duffy, Sandra; Avery, Vicky M; Winzeler, Elizabeth A; Sinden, Robert E; Wittlin, Sergio; Frearson, Julie A; Gray, David W; Fairlamb, Alan H; Waterson, David; Campbell, Simon F; Willis, Paul; Read, Kevin D; Gilbert, Ian H

Transmission-blocking Effects of Primaquine and Methylene Blue Suggest Plasmodium falciparum Gametocyte Sterilization Rather Than Effects on Sex Ratio. (2019) Bradley, John; Soumaré, Harouna M; Mahamar, Almahamoudou; Diawara, Halimatou; Roh, Michelle; Delves, Michael; Drakeley, Chris; Churcher, Thomas S; Dicko, Alassane; Gosling, Roly; Bousema, Teun

Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials. (2019) Children of Eden Primary School; Straschil, Ursula; Witmer, Kathrin; Delves, Michael J; Marks, Stephen D; Baum, Jake

Antimalarial Transmission-Blocking Interventions: Past, Present, and Future. (2018) Delves, MJ; Angrisano, F; Blagborough, AM

A high throughput screen for next-generation leads targeting malaria parasite transmission. (2018) Delves, Michael J; Miguel-Blanco, Celia; Matthews, Holly; Molina, Irene; Ruecker, Andrea; Yahiya, Sabrina; Straschil, Ursula; Abraham, Matthew; León, María Luisa; Fischer, Oliver J; Rueda-Zubiaurre, Ainoa; Brandt, Jochen R; Cortés, Álvaro; Barnard, Anna; Fuchter, Matthew J; Calderón, Félix; Winzeler, Elizabeth A; Sinden, Robert E; Herreros, Esperanza; Gamo, Francisco J; Baum, Jake

A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies. (2010) Delves, Michael J; Sinden, Robert E

Fueling Open Innovation for Malaria Transmission-Blocking Drugs: Hundreds of Molecules Targeting Early Parasite Mosquito Stages. (2019) Delves, Michael; Lafuente-Monasterio, M Jose; Upton, Leanna; Ruecker, Andrea; Leroy, Didier; Gamo, Francisco-Javier; Sinden, Robert

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites. (2012) Delves, Michael; Plouffe, David; Scheurer, Christian; Meister, Stephan; Wittlin, Sergio; Winzeler, Elizabeth A; Sinden, Robert E; Leroy, Didier

Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility. (2014) Kan, Andrey; Tan, Yan-Hong; Angrisano, Fiona; Hanssen, Eric; Rogers, Kelly L; Whitehead, Lachlan; Mollard, Vanessa P; Cozijnsen, Anton; Delves, Michael J; Crawford, Simon; Sinden, Robert E; McFadden, Geoffrey I; Leckie, Christopher; Bailey, James; Baum, Jake

Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development. (2014) Lamour, Sabrina D; Straschil, Ursula; Saric, Jasmina; Delves, Michael J

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling. (2016) Le Bihan, Amélie; de Kanter, Ruben; Angulo-Barturen, Iñigo; Binkert, Christoph; Boss, Christoph; Brun, Reto; Brunner, Ralf; Buchmann, Stephan; Burrows, Jeremy; Dechering, Koen J; Delves, Michael; Ewerling, Sonja; Ferrer, Santiago; Fischli, Christoph; Gamo-Benito, Francisco Javier; Gnädig, Nina F; Heidmann, Bibia; Jiménez-Díaz, María Belén; Leroy, Didier; Martínez, Maria Santos; Meyer, Solange; Moehrle, Joerg J; Ng, Caroline L; Noviyanti, Rintis; Ruecker, Andrea; Sanz, Laura María; Sauerwein, Robert W; Scheurer, Christian; Schleiferboeck, Sarah; Sinden, Robert; Snyder, Christopher; Straimer, Judith; Wirjanata, Grennady; Marfurt, Jutta; Price, Ric N; Weller, Thomas; Fischli, Walter; Fidock, David A; Clozel, Martine; Wittlin, Sergio

Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay. (2015) Leba, Louis-Jérôme; Musset, Lise; Pelleau, Stéphane; Estevez, Yannick; Birer, Caroline; Briolant, Sébastien; Witkowski, Benoit; Ménard, Didier; Delves, Michael J; Legrand, Eric; Duplais, Christophe; Popovici, Jean

Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers. (2018) Malpartida-Cardenas, Kenny; Rodriguez-Manzano, Jesus; Yu, Ling-Shan; Delves, Michael J; Nguon, Chea; Chotivanich, Kesinee; Baum, Jake; Georgiou, Pantelis

Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery. (2016) Marques, Joana; Valle-Delgado, Juan José; Urbán, Patricia; Baró, Elisabet; Prohens, Rafel; Mayor, Alfredo; Cisteró, Pau; Delves, Michael; Sinden, Robert E; Grandfils, Christian; de Paz, José L; García-Salcedo, José A; Fernàndez-Busquets, Xavier

An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission. (2014) Marques, Sara R; Ramakrishnan, Chandra; Carzaniga, Raffaella; Blagborough, Andrew M; Delves, Michael J; Talman, Arthur M; Sinden, Robert E

Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs. (2018) Martí Coma-Cros, Elisabet; Biosca, Arnau; Marques, Joana; Carol, Laura; Urbán, Patricia; Berenguer, Diana; Riera, Maria Cristina; Delves, Michael; Sinden, Robert E; Valle-Delgado, Juan José; Spanos, Lefteris; Siden-Kiamos, Inga; Pérez, Paula; Paaijmans, Krijn; Rottmann, Matthias; Manfredi, Amedea; Ferruti, Paolo; Ranucci, Elisabetta; Fernàndez-Busquets, Xavier

Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen. (2017) Miguel-Blanco, Celia; Molina, Irene; Bardera, Ana I; Díaz, Beatriz; de Las Heras, Laura; Lozano, Sonia; González, Carolina; Rodrigues, Janneth; Delves, Michael J; Ruecker, Andrea; Colmenarejo, Gonzalo; Viera, Sara; Martínez-Martínez, María S; Fernández, Esther; Baum, Jake; Sinden, Robert E; Herreros, Esperanza

The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957. (2021) Miguel-Blanco, Celia; Murithi, James M; Benavente, Ernest Diez; Angrisano, Fiona; Sala, Katarzyna A; van Schalkwyk, Donelly A; Vanaerschot, Manu; Schwach, Frank; Fuchter, Matthew J; Billker, Oliver; Sutherland, Colin J; Campino, Susana G; Clark, Taane G; Blagborough, Andrew M; Fidock, David A; Herreros, Esperanza; Gamo, Francisco Javier; Baum, Jake; Delves, Michael J

Substituted Aminoacetamides as Novel Leads for Malaria Treatment. (2019) Norcross, Neil R; Wilson, Caroline; Baragaña, Beatriz; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Fletcher, Daniel; Sinden, Robert; Delves, Michael; Ruecker, Andrea; Duffy, Sandra; Meister, Stephan; Antonova-Koch, Yevgeniya; Crespo, Benigno; de Cózar, Cristina; Sanz, Laura M; Gamo, Francisco Javier; Avery, Vicky M; Frearson, Julie A; Gray, David W; Fairlamb, Alan H; Winzeler, Elizabeth A; Waterson, David; Campbell, Simon F; Willis, Paul A; Read, Kevin D; Gilbert, Ian H

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance. (2017) O'Neill, Paul M; Amewu, Richard K; Charman, Susan A; Sabbani, Sunil; Gnädig, Nina F; Straimer, Judith; Fidock, David A; Shore, Emma R; Roberts, Natalie L; Wong, Michael H-L; Hong, W David; Pidathala, Chandrakala; Riley, Chris; Murphy, Ben; Aljayyoussi, Ghaith; Gamo, Francisco Javier; Sanz, Laura; Rodrigues, Janneth; Cortes, Carolina Gonzalez; Herreros, Esperanza; Angulo-Barturén, Iñigo; Jiménez-Díaz, María Belén; Bazaga, Santiago Ferrer; Martínez-Martínez, María Santos; Campo, Brice; Sharma, Raman; Ryan, Eileen; Shackleford, David M; Campbell, Simon; Smith, Dennis A; Wirjanata, Grennady; Noviyanti, Rintis; Price, Ric N; Marfurt, Jutta; Palmer, Michael J; Copple, Ian M; Mercer, Amy E; Ruecker, Andrea; Delves, Michael J; Sinden, Robert E; Siegl, Peter; Davies, Jill; Rochford, Rosemary; Kocken, Clemens HM; Zeeman, Anne-Marie; Nixon, Gemma L; Biagini, Giancarlo A; Ward, Stephen A

Structure-Activity Relationship Studies of a Novel Class of Transmission Blocking Antimalarials Targeting Male Gametes. (2019) Rueda-Zubiaurre, Ainoa; Yahiya, Sabrina; Fischer, Oliver J; Hu, Xiaojun; Saunders, Charlie N; Sharma, Sachi; Straschil, Ursula; Shen, Junting; Tate, Edward W; Delves, Michael J; Baum, Jake; Barnard, Anna; Fuchter, Matthew J

Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations. (2014) Upton, LM; Brock, PM; Churcher, TS; Ghani, AC; Gething, PW; Delves, MJ; Sala, KA; Leroy, D; Sinden, RE; Blagborough, AM

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum. (2014) Vaidya, Akhil B; Morrisey, Joanne M; Zhang, Zhongsheng; Das, Sudipta; Daly, Thomas M; Otto, Thomas D; Spillman, Natalie J; Wyvratt, Matthew; Siegl, Peter; Marfurt, Jutta; Wirjanata, Grennady; Sebayang, Boni F; Price, Ric N; Chatterjee, Arnab; Nagle, Advait; Stasiak, Marcin; Charman, Susan A; Angulo-Barturen, Iñigo; Ferrer, Santiago; Belén Jiménez-Díaz, María; Martínez, María Santos; Gamo, Francisco Javier; Avery, Vicky M; Ruecker, Andrea; Delves, Michael; Kirk, Kiaran; Berriman, Matthew; Kortagere, Sandhya; Burrows, Jeremy; Fan, Erkang; Bergman, Lawrence W

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. (2016) Van Voorhis, Wesley C; Adams, John H; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H; Alano, Pietro; Alday, Aintzane; Alemán Resto, Yesmalie; Alsibaee, Aishah; Alzualde, Ainhoa; Andrews, Katherine T; Avery, Simon V; Avery, Vicky M; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; Bowling, Tana; Bosch, Jürgen; Boucher, Lauren E; Boyom, Fabrice F; Brea, Jose; Brennan, Marian; Burton, Audrey; Caffrey, Conor R; Camarda, Grazia; Carrasquilla, Manuela; Carter, Dee; Belen Cassera, Maria; Chih-Chien Cheng, Ken; Chindaudomsate, Worathad; Chubb, Anthony; Colon, Beatrice L; Colón-López, Daisy D; Corbett, Yolanda; Crowther, Gregory J; Cowan, Noemi; D'Alessandro, Sarah; Le Dang, Na; Delves, Michael; DeRisi, Joseph L; Du, Alan Y; Duffy, Sandra; Abd El-Salam El-Sayed, Shimaa; Ferdig, Michael T; Fernández Robledo, José A; Fidock, David A; Florent, Isabelle; Fokou, Patrick VT; Galstian, Ani; Gamo, Francisco Javier; Gokool, Suzanne; Gold, Ben; Golub, Todd; Goldgof, Gregory M; Guha, Rajarshi; Guiguemde, W Armand; Gural, Nil; Guy, R Kiplin; Hansen, Michael AE; Hanson, Kirsten K; Hemphill, Andrew; Hooft van Huijsduijnen, Rob; Horii, Takaaki; Horrocks, Paul; Hughes, Tyler B; Huston, Christopher; Igarashi, Ikuo; Ingram-Sieber, Katrin; Itoe, Maurice A; Jadhav, Ajit; Naranuntarat Jensen, Amornrat; Jensen, Laran T; Jiang, Rays HY; Kaiser, Annette; Keiser, Jennifer; Ketas, Thomas; Kicka, Sebastien; Kim, Sunyoung; Kirk, Kiaran; Kumar, Vidya P; Kyle, Dennis E; Lafuente, Maria Jose; Landfear, Scott; Lee, Nathan; Lee, Sukjun; Lehane, Adele M; Li, Fengwu; Little, David; Liu, Liqiong; Llinás, Manuel; Loza, Maria I; Lubar, Aristea; Lucantoni, Leonardo; Lucet, Isabelle; Maes, Louis; Mancama, Dalu; Mansour, Nuha R; March, Sandra; McGowan, Sheena; Medina Vera, Iset; Meister, Stephan; Mercer, Luke; Mestres, Jordi; Mfopa, Alvine N; Misra, Raj N; Moon, Seunghyun; Moore, John P; Morais Rodrigues da Costa, Francielly; Müller, Joachim; Muriana, Arantza; Nakazawa Hewitt, Stephen; Nare, Bakela; Nathan, Carl; Narraidoo, Nathalie; Nawaratna, Sujeevi; Ojo, Kayode K; Ortiz, Diana; Panic, Gordana; Papadatos, George; Parapini, Silvia; Patra, Kailash; Pham, Ngoc; Prats, Sarah; Plouffe, David M; Poulsen, Sally-Ann; Pradhan, Anupam; Quevedo, Celia; Quinn, Ronald J; Rice, Christopher A; Abdo Rizk, Mohamed; Ruecker, Andrea; St Onge, Robert; Salgado Ferreira, Rafaela; Samra, Jasmeet; Robinett, Natalie G; Schlecht, Ulrich; Schmitt, Marjorie; Silva Villela, Filipe; Silvestrini, Francesco; Sinden, Robert; Smith, Dennis A; Soldati, Thierry; Spitzmüller, Andreas; Stamm, Serge Maximilian; Sullivan, David J; Sullivan, William; Suresh, Sundari; Suzuki, Brian M; Suzuki, Yo; Swamidass, S Joshua; Taramelli, Donatella; Tchokouaha, Lauve RY; Theron, Anjo; Thomas, David; Tonissen, Kathryn F; Townson, Simon; Tripathi, Abhai K; Trofimov, Valentin; Udenze, Kenneth O; Ullah, Imran; Vallieres, Cindy; Vigil, Edgar; Vinetz, Joseph M; Voong Vinh, Phat; Vu, Hoan; Watanabe, Nao-Aki; Weatherby, Kate; White, Pamela M; Wilks, Andrew F; Winzeler, Elizabeth A; Wojcik, Edward; Wree, Melanie; Wu, Wesley; Yokoyama, Naoaki; Zollo, Paul HA; Abla, Nada; Blasco, Benjamin; Burrows, Jeremy; Laleu, Benoît; Leroy, Didier; Spangenberg, Thomas; Wells, Timothy; Willis, Paul A

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria. (2014) White, Nicholas J; Ashley, Elizabeth A; Recht, Judith; Delves, Michael J; Ruecker, Andrea; Smithuis, Frank M; Eziefula, Alice C; Bousema, Teun; Drakeley, Chris; Chotivanich, Kesinee; Imwong, Mallika; Pukrittayakamee, Sasithon; Prachumsri, Jetsumon; Chu, Cindy; Andolina, Chiara; Bancone, Germana; Hien, Tran T; Mayxay, Mayfong; Taylor, Walter RJ; von Seidlein, Lorenz; Price, Ric N; Barnes, Karen I; Djimdé, Abdoulaye; ter Kuile, Feiko; Gosling, Roly; Chen, Ingrid; Dhorda, Mehul J; Stepniewska, Kasia; Guérin, Philippe; Woodrow, Charles J; Dondorp, Arjen M; Day, Nicholas PJ; Nosten, Francois H

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles. (2016) Williamson, Alice E; Ylioja, Paul M; Robertson, Murray N; Antonova-Koch, Yevgeniya; Avery, Vicky; Baell, Jonathan B; Batchu, Harikrishna; Batra, Sanjay; Burrows, Jeremy N; Bhattacharyya, Soumya; Calderon, Felix; Charman, Susan A; Clark, Julie; Crespo, Benigno; Dean, Matin; Debbert, Stefan L; Delves, Michael; Dennis, Adelaide SM; Deroose, Frederik; Duffy, Sandra; Fletcher, Sabine; Giaever, Guri; Hallyburton, Irene; Gamo, Francisco-Javier; Gebbia, Marinella; Guy, R Kiplin; Hungerford, Zoe; Kirk, Kiaran; Lafuente-Monasterio, Maria J; Lee, Anna; Meister, Stephan; Nislow, Corey; Overington, John P; Papadatos, George; Patiny, Luc; Pham, James; Ralph, Stuart A; Ruecker, Andrea; Ryan, Eileen; Southan, Christopher; Srivastava, Kumkum; Swain, Chris; Tarnowski, Matthew J; Thomson, Patrick; Turner, Peter; Wallace, Iain M; Wells, Timothy NC; White, Karen; White, Laura; Willis, Paul; Winzeler, Elizabeth A; Wittlin, Sergio; Todd, Matthew H

Transmission of Artemisinin-Resistant Malaria Parasites to Mosquitoes under Antimalarial Drug Pressure. (2021) Witmer, Kathrin; Dahalan, Farah A; Delves, Michael J; Yahiya, Sabrina; Watson, Oliver J; Straschil, Ursula; Chiwcharoen, Darunee; Sornboon, Boodtee; Pukrittayakamee, Sasithon; Pearson, Richard D; Howick, Virginia M; Lawniczak, Mara KN; White, Nicholas J; Dondorp, Arjen M; Okell, Lucy C; Chotivanich, Kesinee; Ruecker, Andrea; Baum, Jake

An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies. (2018) Witmer, Kathrin; Sherrard-Smith, Ellie; Straschil, Ursula; Tunnicliff, Mark; Baum, Jake; Delves, Michael

The antimalarial screening landscape-looking beyond the asexual blood stage. (2019) Yahiya, Sabrina; Rueda-Zubiaurre, Ainoa; Delves, Michael J; Fuchter, Matthew J; Baum, Jake

A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein. (2023) Yahiya, Sabrina; Saunders, Charlie N; Hassan, Sarah; Straschil, Ursula; Fischer, Oliver J; Rueda-Zubiaurre, Ainoa; Haase, Silvia; Vizcay-Barrena, Gema; Famodimu, Mufuliat Toyin; Jordan, Sarah; Delves, Michael J; Tate, Edward W; Barnard, Anna; Fuchter, Matthew J; Baum, Jake

Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. (2019) Zeeshan, Mohammad; Ferguson, David Jp; Abel, Steven; Burrrell, Alana; Rea, Edward; Brady, Declan; Daniel, Emilie; Delves, Michael; Vaughan, Sue; Holder, Anthony A; Le Roch, Karine G; Moores, Carolyn A; Tewari, Rita