Items where Author is "Seifert, Karin"

Number of items: 27.
2018
  • Histopathological and immunohistochemical characterisation of hepatic granulomas in Leishmania donovani-infected BALB/c mice: a time-course study. (2018) Salguero, Francisco J; Garcia-Jimenez, Waldo L; Lima, Isadora; Seifert, Karin
  • Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages. (2018) Voak, Andrew A; Standing, Joseph F; Sepúlveda, Nuno; Harris, Andy; Croft, Simon L; Seifert, Karin
    • 2017
  • Snapshot Profiling of the Antileishmanial Potency of Lead Compounds and Drug Candidates against Intracellular Leishmania donovani Amastigotes, with a Focus on Human-Derived Host Cells. (2017) Koniordou, Markela; Patterson, Stephen; Wyllie, Susan; Seifert, Karin
  • Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs. (2017) Meredith, Emma Louise; Kumar, Ambika; Konno, Aya; Szular, Joanna; Alsford, Sam; Seifert, Karin; Horn, David; Wilkinson, Shane R
    • 2015
  • Chemical and bioassay techniques to authenticate quality of the anti-leishmanial drug miltefosine. (2015) Kaur, Harparkash; Seifert, Karin; Hawkes, Geoffrey E; Coumbarides, Gregory S; Alvar, Jorge; Croft, Simon L
  • Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. (2015) Riede, O; Seifert, K; Oswald, D; Endmann, A; Hock, C; Winkler, A; Salguero, FJ; Schroff, M; Croft, SL; Juhls, C
  • Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate. (2015) Seifert, Karin; Juhls, Christiane; Salguero, Francisco J; Croft, Simon L
    • 2014
  • Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. (2014) Das, Shantanabha; Freier, Anja; Boussoffara, Thouraya; Das, Sushmita; Oswald, Detlef; Losch, Florian O; Selka, Melanie; Sacerdoti-Sierra, Nina; Schönian, Gabriele; Wiesmüller, Karl-Heinz; Seifert, Karin; Schroff, Matthias; Juhls, Christiane; Jaffe, Charles L; Roy, Syamal; Das, Pradeep; Louzir, Hechmi; Croft, Simon L; Modabber, Farrokh; Walden, Peter
  • Metabolic, immune, and gut microbial signals mount a systems response to Leishmania major infection. (2014) Lamour, Sabrina D; Veselkov, Kirill A; Posma, Joram M; Giraud, Emilie; Rogers, Matthew E; Croft, Simon; Marchesi, Julian R; Holmes, Elaine; Seifert, Karin; Saric, Jasmina
    • 2013
  • Noncovalent complexation of amphotericin-B with Poly(α-glutamic acid). (2013) Mohamed-Ahmed, Abeer HA; Les, Karolina A; Seifert, Karin; Croft, Simon L; Brocchini, Stephen
  • Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(α-Glutamic Acid) complex. (2013) Mohamed-Ahmed, Abeer HA; Seifert, Karin; Yardley, Vanessa; Burrell-Saward, Hollie; Brocchini, Stephen; Croft, Simon L
  • An essential type I nitroreductase from Leishmania major can be used to activate leishmanicidal prodrugs. (2013) Voak, Andrew A; Gobalakrishnapillai, Vithurshaa; Seifert, Karin; Balczo, Edina; Hu, Longqin; Hall, Belinda S; Wilkinson, Shane R
  • Evaluating aziridinyl nitrobenzamide compounds as leishmanicidal prodrugs. (2013) Voak, Andrew A; Seifert, Karin; Helsby, Nuala A; Wilkinson, Shane R
    • 2011
  • Structures, targets and recent approaches in anti-leishmanial drug discovery and development. (2011) Seifert, Karin
  • In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani. (2011) Seifert, Karin; Munday, Jane; Syeda, Tahmina; Croft, Simon L
    • 2010
  • Water-soluble polymer-drug conjugates for combination chemotherapy against visceral leishmaniasis. (2010) Nicoletti, Salvatore; Seifert, Karin; Gilbert, Ian H
  • In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. (2010) Seifert, Karin; Escobar, Patricia; Croft, Simon L
    • 2009
  • N-(2-hydroxypropyl)methacrylamide-amphotericin B (HPMA-AmB) copolymer conjugates as antileishmanial agents. (2009) Nicoletti, Salvatore; Seifert, Karin; Gilbert, Ian H picture_as_pdf
    • 2007
  • Antileishmanial structure-activity relationships of synthetic phospholipids: in vitro and in vivo activities of selected derivatives. (2007) Seifert, Karin; Lemke, Andreas; Croft, Simon L; Kayser, Oliver
  • Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. (2007) Seifert, Karin; Pérez-Victoria, F Javier; Stettler, Marianne; Sánchez-Cañete, María P; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L
    • 2006
  • Current scenario of drug development for leishmaniasis. (2006) Croft, Simon L; Seifert, Karin; Yardley, Vanessa
  • Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. (2006) Pérez-Victoria, F Javier; Sánchez-Cañete, María P; Seifert, Karin; Croft, Simon L; Sundar, Shyam; Castanys, Santiago; Gamarro, Francisco
  • In vitro and in vivo interactions between miltefosine and other antileishmanial drugs. (2006) Seifert, Karin; Croft, Simon L
    • 2003
  • Antiprotozoal activities of phospholipid analogues. (2003) Croft, Simon L; Seifert, Karin; Duchêne, Michael
  • Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). (2003) Seifert, Karin; Matu, Sangeeta; Javier Pérez-Victoria, F; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L
    • 2002
  • Cytotoxic activities of alkylphosphocholines against clinical isolates of Acanthamoeba spp. (2002) Walochnik, Julia; Duchêne, Michael; Seifert, Karin; Obwaller, Andreas; Hottkowitz, Thomas; Wiedermann, Gerhard; Eibl, Hansjörg; Aspöck, Horst
    • 2001
  • Effects of miltefosine and other alkylphosphocholines on human intestinal parasite Entamoeba histolytica. (2001) Seifert, K; Duchêne, M; Wernsdorfer, WH; Kollaritsch, H; Scheiner, O; Wiedermann, G; Hottkowitz, T; Eibl, H