Items where Author is "van Schalkwyk, Donelly A"

Year Item Type Full Text

Article

Semi-Synthetic Analogues of Cryptolepine as a Potential Source of Sustainable Drugs for the Treatment of Malaria, Human African Trypanosomiasis, and Cancer. (2022) Abacha, Yabalu Z; Forkuo, Arnold Donkor; Gbedema, Stephen Y; Mittal, Nimisha; Ottilie, Sabine; Rocamora, Frances; Winzeler, Elizabeth A; van Schalkwyk, Donelly A; Kelly, John M; Taylor, Martin C; Reader, Janette; Birkholtz, Lyn-Marie; Lisgarten, David R; Cockcroft, Jeremy K; Lisgarten, John N; Palmer, Rex A; Talbert, Rosemary C; Shnyder, Steven D; Wright, Colin W

Clinical Validation of a Commercial LAMP Test for Ruling out Malaria in Returning Travelers: A Prospective Diagnostic Trial. (2018) Cheaveau, James; Nguyen, Hong; Chow, Barbara; Marasinghe, Dewdunee; Mohon, Abu Naser; Yuan, Hong; Viana, Gisele; van Schalkwyk, Donelly; Church, Deirdre; Chan, Wilson; Pillai, Dylan R

Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains. (2014) Chugh, Monika; Scheurer, Christian; Sax, Sibylle; Bilsland, Elizabeth; van Schalkwyk, Donelly A; Wicht, Kathryn J; Hofmann, Natalie; Sharma, Anil; Bashyam, Sridevi; Singh, Shivendra; Oliver, Stephen G; Egan, Timothy J; Malhotra, Pawan; Sutherland, Colin J; Beck, Hans-Peter; Wittlin, Sergio; Spangenberg, Thomas; Ding, Xavier C

Corrigendum to 'A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections'. (2021) Grignard, Lynn; Nolder, Debbie; Sepulveda, Nuno; Berhane, Araia; Mihreteab, Selam; Kaaya, Robert; Phelan, Jody; Moser, Kara; van Schalkwyk, Donelly A; Campino, Susana; Parr, Jonathan B; Juliano, Jonathan J; Chiodini, Peter; Cunningham, Jane; Sutherland, Colin J; Drakeley, Chris; Beshir, Khalid B

A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections. (2020) Grignard, Lynn; Nolder, Debbie; Sepúlveda, Nuno; Berhane, Araia; Mihreteab, Selam; Kaaya, Robert; Phelan, Jody; Moser, Kara; van Schalkwyk, Donelly A; Campino, Susana; Parr, Jonathan B; Juliano, Jonathan J; Chiodini, Peter; Cunningham, Jane; Sutherland, Colin J; Drakeley, Chris; Beshir, Khalid B picture_as_pdf

Degradation of Artemisinin-Based Combination Therapies Under Tropical Conditions. (2016) Hall, Zoe; Allan, Elizabeth Louise; van Schalkwyk, Donelly Andrew; van Wyk, Albert; Kaur, Harparkash

The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. (2020) Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J

The Plasmodium falciparum Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation. (2020) Henrici, Ryan C; Edwards, Rachel L; Zoltner, Martin; van Schalkwyk, Donelly A; Hart, Melissa N; Mohring, Franziska; Moon, Robert W; Nofal, Stephanie D; Patel, Avnish; Flueck, Christian; Baker, David A; Odom John, Audrey R; Field, Mark C; Sutherland, Colin J

Modification of pfap2μ and pfubp1 Markedly Reduces Ring-Stage Susceptibility of Plasmodium falciparum to Artemisinin In Vitro. (2019) Henrici, Ryan C; van Schalkwyk, Donelly A; Sutherland, Colin J

Transient temperature fluctuations severely decrease P. falciparum susceptibility to artemisinin in vitro. (2019) Henrici, Ryan C; van Schalkwyk, Donelly A; Sutherland, Colin J

Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT. (2014) Henriques, Gisela; Hallett, Rachel L; Beshir, Khalid B; Gadalla, Nahla B; Johnson, Rachel E; Burrow, Rebekah; van Schalkwyk, Donelly A; Sawa, Patrick; Omar, Sabah A; Clark, Taane G; Bousema, Teun; Sutherland, Colin J

The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine. (2015) Henriques, Gisela; van Schalkwyk, Donelly A; Burrow, Rebekah; Warhurst, David C; Thompson, Eloise; Baker, David A; Fidock, David A; Hallett, Rachel; Flueck, Christian; Sutherland, Colin J

The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957. (2021) Miguel-Blanco, Celia; Murithi, James M; Benavente, Ernest Diez; Angrisano, Fiona; Sala, Katarzyna A; van Schalkwyk, Donelly A; Vanaerschot, Manu; Schwach, Frank; Fuchter, Matthew J; Billker, Oliver; Sutherland, Colin J; Campino, Susana G; Clark, Taane G; Blagborough, Andrew M; Fidock, David A; Herreros, Esperanza; Gamo, Francisco Javier; Baum, Jake; Delves, Michael J

Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs. (2022) Mohring, Franziska; van Schalkwyk, Donelly A; Henrici, Ryan C; Blasco, Benjamin; Leroy, Didier; Sutherland, Colin J; Moon, Robert W

Failure of rapid diagnostic tests in Plasmodium falciparum malaria cases among travelers to the UK and Ireland: Identification and characterisation of the parasites. (2021) Nolder, Debbie; Stewart, Lindsay; Tucker, Julie; Ibrahim, Amy; Gray, Adam; Corrah, Tumena; Gallagher, Carmel; John, Laurence; O'Brien, Edel; Aggarwal, Dinesh; Benavente, Ernest Diez; van Schalkwyk, Donelly; Henriques, Gisela; Sepúlveda, Nuno; Campino, Susana; Chiodini, Peter; Sutherland, Colin; Beshir, Khalid B

pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom. (2017) Sutherland, Colin J; Lansdell, Paul; Sanders, Mandy; Muwanguzi, Julian; van Schalkwyk, Donelly A; Kaur, Harparkash; Nolder, Debbie; Tucker, Julie; Bennett, Hayley M; Otto, Thomas D; Berriman, Matthew; Patel, Trupti A; Lynn, Roderick; Gkrania-Klotsas, Effrossyni; Chiodini, Peter L

Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum. (2022) Tan, Angelica F; Sakam, Sitti Saimah Binti; Rajahram, Giri S; William, Timothy; Abd Rachman Isnadi, Mohammad Faruq; Daim, Sylvia; Barber, Bridget E; Kho, Steven; Sutherland, Colin J; Anstey, Nicholas M; Yerlikaya, Seda; van Schalkwyk, Donelly A; Grigg, Matthew J

Paper-Origami-Based Multiplexed Malaria Diagnostics from Whole Blood. (2016) Xu, Gaolian; Nolder, Debbie; Reboud, Julien; Oguike, Mary C; van Schalkwyk, Donelly A; Sutherland, Colin J; Cooper, Jonathan M

Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum. (2019) van Schalkwyk, Donelly A; Blasco, Benjamin; Davina Nuñez, Rocio; Liew, Jonathan WK; Amir, Amirah; Lau, Yee L; Leroy, Didier; Moon, Robert W; Sutherland, Colin J

Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers. (2013) van Schalkwyk, Donelly A; Burrow, Rebekah; Henriques, Gisela; Gadalla, Nahla B; Beshir, Khalid B; Hasford, Christian; Wright, Stephen G; Ding, Xavier C; Chiodini, Peter L; Sutherland, Colin J

Comparison of the susceptibility of Plasmodium knowlesi and Plasmodium falciparum to antimalarial agents. (2017) van Schalkwyk, Donelly A; Moon, Robert W; Blasco, Benjamin; Sutherland, Colin J

Ex vivo susceptibility to new antimalarial agents differs among human-infecting Plasmodium species. (2021) van Schalkwyk, Donelly A; Moon, Robert W; Duffey, Maëlle; Leroy, Didier; Sutherland, Colin J

Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs. (2015) van Schalkwyk, Donelly A; Nash, Megan N; Shafik, Sarah H; Summers, Robert L; Lehane, Adele M; Smith, Peter J; Martin, Rowena E

Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil. (2020) van Schalkwyk, Donelly A; Riscoe, Michael K; Pou, Sovitj; Winter, Rolf W; Nilsen, Aaron; Duffey, Maëlle; Moon, Robert W; Sutherland, Colin J

Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil. (2020) van Schalkwyk, Donelly A; Riscoe, Michael K; Pou, Sovitj; Winter, Rolf W; Nilsen, Aaron; Duffey, Maëlle; Moon, Robert W; Sutherland, Colin J

Malaria resistance to non-artemisinin partner drugs: how to reACT. (2015) van Schalkwyk, Donelly A; Sutherland, Colin J

We must go for gold in public health. (2016) van Schalkwyk, May CI; van Schalkwyk, Donelly A