Items where Author is "Sharples, Linda D"
Number of items: 91.
2022
  • Linkage of multiple electronic health record datasets using a 'spine linkage' approach compared with all 'pairwise linkages'. (2022) Blake, Helen A; Sharples, Linda D; Harron, Katie; van der Meulen, Jan H; Walker, Kate
  • Impact of changes to the interscreening interval and faecal immunochemical test threshold in the national bowel cancer screening programme in England: results from the FIT pilot study. (2022) Li, Shuping J; Seedher, Tara; Sharples, Linda D; Benton, Sally C; Mathews, Christopher; Gabe, Rhian; Sasieni, Peter; Duffy, Stephen W
  • Reply to García-Villarreal et al. (2022) Nashef, Samer AM; Sharples, Linda D picture_as_pdf
  • Time-varying Comparison of All-cause Mortality After Liver Transplantation Between Recipients With and Without Hepatocellular Carcinoma: A Population-based Cohort Study Using the United Kingdom Liver Transplant Registry. (2022) Sehjal, Jyoti; Sharples, Linda D; Keogh, Ruth H; Walker, Kate; Prachalias, Andreas; Heaton, Nigel; Ivanics, Tommy; van der Meulen, Jan; Wallace, David
  • Five-year results of Amaze: a randomized controlled trial of adjunct surgery for atrial fibrillation. (2022) Sharples, Linda D; Mills, Christine; Chiu, Yi-Da; Fynn, Simon; Holcombe, Helen M; Nashef, Samer AM
  • Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study. (2022) Sharples, Linda; Sastry, Priya; Freeman, Carol; Gray, Joanne; McCarthy, Andrew; Chiu, Yi-Da; Bicknell, Colin; McMeekin, Peter; Vallabhaneni, S Rao; Cook, Andrew; Vale, Luke; Large, Stephen
  • Mediation of the total effect of cystic fibrosis-related diabetes on mortality: A UK Cystic Fibrosis Registry cohort study. (2022) Tanner, Kamaryn T; Daniel, Rhian M; Bilton, Diana; Simmonds, Nicholas J; Sharples, Linda D; Keogh, Ruth H
  • Methods of analysis for survival outcomes with time-updated mediators, with application to longitudinal disease registry data. (2022) Tanner, Kamaryn T; Sharples, Linda D; Daniel, Rhian M; Keogh, Ruth H
  • 2021
  • Probabilistic linkage without personal information successfully linked national clinical datasets. (2021) Blake, Helen A; Sharples, Linda D; Harron, Katie; van der Meulen, Jan H; Walker, Kate
  • Reference Case Methods for Expert Elicitation in Health Care Decision Making. (2021) Bojke, Laura; Soares, Marta O; Claxton, Karl; Colson, Abigail; Fox, Aimée; Jackson, Chris; Jankovic, Dina; Morton, Alec; Sharples, Linda D; Taylor, Andrea
  • Developing a reference protocol for structured expert elicitation in health-care decision-making: a mixed-methods study. (2021) Bojke, Laura; Soares, Marta; Claxton, Karl; Colson, Abigail; Fox, Aimée; Jackson, Christopher; Jankovic, Dina; Morton, Alec; Sharples, Linda; Taylor, Andrea
  • Logistic regression and machine learning predicted patient mortality from large sets of diagnosis codes comparably. (2021) Cowling, Thomas E; Cromwell, David A; Bellot, Alexis; Sharples, Linda D; van der Meulen, Jan
  • Frequentist rules for regulatory approval of subgroups in phase III trials: A fresh look at an old problem. (2021) Edgar, K; Jackson, D; Rhodes, K; Duffy, T; Burman, C-F; Sharples, LD
  • Including random centre effects in design, analysis and presentation of multi-centre trials. (2021) Edgar, Kate; Roberts, Ian; Sharples, Linda
  • Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms. (2021) McCarthy, Andrew; Gray, Joanne; Sastry, Priya; Sharples, Linda; Vale, Luke; Cook, Andrew; Mcmeekin, Peter; Freeman, Carol; Catarino, Pedro; Large, Stephen
  • Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study. (2021) Sharples, Linda; Sastry, Priya; Freeman, Carol; Bicknell, Colin; Chiu, Yi Da; Vallabhaneni, Srinivasa Rao; Cook, Andrew; Gray, Joanne; McCarthy, Andrew; McMeekin, Peter; Vale, Luke; Large, Stephen
  • Power and sample size for multistate model analysis of longitudinal discrete outcomes in disease prevention trials. (2021) Smith, Isabelle L; Nixon, Jane E; Sharples, Linda
  • Dynamic Prediction, Mediation and Communication for Survival Outcomes, with applications to Cystic Fibrosis. (2021) Tanner, KT
  • 2020
  • Multiple Interventions for Diabetic Foot Ulcer Treatment Trial (MIDFUT): study protocol for a randomised controlled trial. (2020) Brown, Sarah; Nixon, Jane; Ransom, Myka; Gilberts, Rachael; Dewhirst, Nikki; McGinnis, Elizabeth; Longo, Roberta; Game, Frances; Bojke, Chris; Chadwick, Paul; Chandrasekar, Akila; Chetter, Ian; Collier, Howard; Fernandez, Catherine; Homer-Vanniasinkam, Shervanthi; Jude, Edward; Leigh, Richard; Lomas, Richard; Vowden, Peter; Wason, James; Sharples, Linda; Russell, David
  • One-year mortality of colorectal cancer patients: development and validation of a prediction model using linked national electronic data. (2020) Cowling, Thomas E; Bellot, Alexis; Boyle, Jemma; Walker, Kate; Kuryba, Angela; Galbraith, Sarah; Aggarwal, Ajay; Braun, Michael; Sharples, Linda D; van der Meulen, Jan
  • A novel approach selected small sets of diagnosis codes with high prediction performance in large healthcare datasets. (2020) Cowling, Thomas E; Cromwell, David A; Sharples, Linda D; van der Meulen, Jan
  • Rationale and design of the LIBERATES trial: Protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction. (2020) Everett, Colin C; Reynolds, Catherine; Fernandez, Catherine; Stocken, Deborah D; Sharples, Linda D; Sathyapalan, Thozhukat; Heller, Simon; Storey, Robert F; Ajjan, Ramzi A
  • Evaluating the effect of healthcare providers on the clinical path of heart failure patients through a semi-Markov, multi-state model. (2020) Gasperoni, Francesca; Ieva, Francesca; Paganoni, Anna Maria; Jackson, Christopher H; Sharples, Linda
  • Faecal immunochemical testing in bowel cancer screening: Estimating outcomes for different diagnostic policies. (2020) Li, Shuping J; Sharples, Linda D; Benton, Sally C; Blyuss, Oleg; Mathews, Christopher; Sasieni, Peter; Duffy, Stephen W
  • Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results. (2020) Mansukhani, Raoul; Frimley, Lauren; Shakur-Still, Haleema; Sharples, Linda; Roberts, Ian
  • Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis. (2020) Myat, Aung; Papachristofi, Olympia; Trivedi, Uday; Bapat, Vinayak; Young, Christopher; de Belder, Adam; Cockburn, James; Baumbach, Andreas; Banning, Adrian P; Blackman, Daniel J; MacCarthy, Philip; Mullen, Michael; Muir, Douglas F; Nolan, James; Zaman, Azfar; de Belder, Mark; Cox, Ian; Kovac, Jan; Brecker, Stephen; Turner, Mark; Khogali, Saib; Malik, Iqbal; Redwood, Simon; Prendergast, Bernard; Ludman, Peter; Sharples, Linda; Hildick-Smith, David
  • Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis. (2020) Myat, Aung; Papachristofi, Olympia; Trivedi, Uday; Bapat, Vinayak; Young, Christopher; de Belder, Adam; Cockburn, James; Baumbach, Andreas; Banning, Adrian P; Blackman, Daniel J; MacCarthy, Philip; Mullen, Michael; Muir, Douglas F; Nolan, James; Zaman, Azfar; de Belder, Mark; Cox, Ian; Kovac, Jan; Brecker, Stephen; Turner, Mark; Khogali, Saib; Malik, Iqbal; Redwood, Simon; Prendergast, Bernard; Ludman, Peter; Sharples, Linda; Hildick-Smith, David
  • Exploring mechanisms of action in clinical trials of complex surgical interventions using mediation analysis. (2020) Sharples, Linda; Papachristofi, Olympia; Rex, Saleema; Landau, Sabine
  • Dynamic Survival Prediction Combining Landmarking with a Machine Learning Ensemble: Methodology and Empirical Comparison. (2020) Tanner, Kamaryn T; Sharples, Linda D; Daniel, Rhian M; Keogh, Ruth H
  • 2019
  • Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomised registry-based trial. (2019) Everett, Colin C; Fox, Keith Aa; Reynolds, Catherine; Fernandez, Catherine; Sharples, Linda; Stocken, Deborah D; Carruthers, Kathryn; Hemingway, Harry; Yan, Andrew T; Goodman, Shaun G; Brieger, David; Chew, Derek P; Gale, Chris P
  • Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome: protocol of the UKGRIS cluster-randomised registry-based trial. (2019) Everett, Colin; Fox, Keith; Reynolds, Catherine; Fernandez, Catherine; Sharples, Linda; Stocken, Deborah; Carruthers, Kathryn; Hemmingway, Harry; Yan, Andrew; Goodman, Shaun; Brieger, David; Chew, Derek; Gale, Chris
  • Nonproportional Hazards for Time-to-Event Outcomes in Clinical Trials: JACC Review Topic of the Week. (2019) Gregson, John; Sharples, Linda; Stone, Gregg W; Burman, Carl-Fredrik; Öhrn, Fredrik; Pocock, Stuart
  • MesoTRAP: a feasibility study that includes a pilot clinical trial comparing video-assisted thoracoscopic partial pleurectomy decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed to address recruitment and randomisation uncertainties and sample size requirements for a phase III trial. (2019) Matthews, Claire; Freeman, Carol; Sharples, Linda D; Fox-Rushby, Julia; Tod, Angela; Maskell, Nicholas A; Edwards, John G; Coonar, Aman S; Sivasothy, Pasupathy; Hughes, Victoria; Rahman, Najib M; Waller, David A; Rintoul, Robert Campbell
  • A systematic review and meta-analysis estimating the population prevalence of comorbidities in children and adolescents aged 5 to 18 years. (2019) Sharma, Vishal; Coleman, Susanne; Nixon, Jane; Sharples, Linda; Hamilton-Shield, Julian; Rutter, Harry; Bryant, Maria
  • 2018
  • Alternative tumour necrosis factor inhibitors (TNFi) or abatacept or rituximab following failure of initial TNFi in rheumatoid arthritis: the SWITCH RCT. (2018) Brown, S; Everett, CC; Naraghi, K; Davies, C; Dawkins, B; Hulme, C; McCabe, C; Pavitt, S; Emery, P; Sharples, L; Buch, MH
  • Non-parametric frailty Cox models for hierarchical time-to-event data. (2018) Gasperoni, Francesca; Ieva, Francesca; Paganoni, Anna Maria; Jackson, Christopher H; Sharples, Linda
  • Mini-Stern Trial: A randomised trial comparing mini-sternotomy to full median sternotomy for aortic valve replacement. (2018) Nair, SK; Sudarshan, CD; Thorpe, BS; Singh, J; Pillay, T; Catarino, P; Valchanov, K; Codispoti, M; Dunning, J; Abu-Omar, Y; Moorjani, N; Matthews, C; Freeman, CJ; Fox-Rushby, JA; Sharples, LD
  • Mini-Stern Trial: A randomized trial comparing mini-sternotomy to full median sternotomy for aortic valve replacement. (2018) Nair, Sukumaran K; Sudarshan, Catherine D; Thorpe, Benjamin S; Singh, Jeshika; Pillay, Thasee; Catarino, Pedro; Valchanov, Kamen; Codispoti, Massimiliano; Dunning, John; Abu-Omar, Yasir; Moorjani, Narain; Matthews, Claire; Freeman, Carol J; Fox-Rushby, Julia A; Sharples, Linda D
  • Amaze: a randomized controlled trial of adjunct surgery for atrial fibrillation. (2018) Nashef, Samer AM; Fynn, Simon; Abu-Omar, Yasir; Spyt, Tomasz J; Mills, Christine; Everett, Colin C; Fox-Rushby, Julia; Singh, Jeshika; Dalrymple-Hay, Malcolm; Sudarshan, Catherine; Codispoti, Massimiliano; Braidley, Peter; Wells, Francis C; Sharples, Linda D
  • Does the "Weekend Effect" for Postoperative Mortality Stand Up to Scrutiny? Association for Cardiothoracic Anesthesia and Critical Care Cohort Study of 110,728 Cardiac Surgical Patients. (2018) Papachristofi, Olympia; Klein, Andrew A; Mackay, John; Nashef, Samer; Fletcher, Nick S; Sharples, Linda D; Association for Cardiothoracic Anaesthesia and Critical Care (AC
  • The role of statistics in the era of big data: Electronic health records for healthcare research. (2018) Sharples, Linda D
  • Amaze: a double-blind, multicentre randomised controlled trial to investigate the clinical effectiveness and cost-effectiveness of adding an ablation device-based maze procedure as an adjunct to routine cardiac surgery for patients with pre-existing atrial fibrillation. (2018) Sharples, Linda; Everett, Colin; Singh, Jeshika; Mills, Christine; Spyt, Tom; Abu-Omar, Yasir; Fynn, Simon; Thorpe, Benjamin; Stoneman, Victoria; Goddard, Hester; Fox-Rushby, Julia; Nashef, Samer
  • Experiences of Structured Elicitation for Model-Based Cost-Effectiveness Analyses. (2018) Soares, Marta O; Sharples, Linda; Morton, Alec; Claxton, Karl; Bojke, Laura
  • 2017
  • Recovery of Left Atrial Contractile Function After Maze Surgery in Persistent Longstanding Atrial Fibrillation. (2017) Abu-Omar, Yasir; Thorpe, Benjamin S; Freeman, Carol; Mills, Christine; Stoneman, Victoria EA; Gopalan, Deepa; Rana, Bushra; Spyt, Tomasz J; Sharples, Linda D; Nashef, Samer AM
  • Randomized Controlled Trial of Rituximab and cost-effectiveness analysis in treating fatigue and oral dryness in primary Sjogren's Syndrome. (2017) Bowman, SJ; Everett, CC; O'Dwyer, JL; Emery, P; Pitzalis, C; Ng, WF; Pease, CT; Price, EJ; Sutcliffe, N; St Gendi, N; Hall, FC; Ruddock, SP; Fernandez, C; Reynolds, C; Hulme, CT; Davies, KA; Edwards, CJ; Lanyon, PC; Moots, RJ; Roussou, E; Giles, IP; Sharples, LD; Bombardieri, M
  • The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials. (2017) Clayton, Gemma L; Smith, Isabelle L; Higgins, Julian PT; Mihaylova, Borislava; Thorpe, Benjamin; Cicero, Robert; Lokuge, Kusal; Forman, Julia R; Tierney, Jayne F; White, Ian R; Sharples, Linda D; Jones, Hayley E
  • Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. (2017) Fisher, Benjamin A; Everett, Colin C; Rout, John; O'Dwyer, John L; Emery, Paul; Pitzalis, Costantino; Ng, Wan-Fai; Carr, Andrew; Pease, Colin T; Price, Elizabeth J; Sutcliffe, Nurhan; Makdissi, Jimmy; Tappuni, Anwar R; Gendi, Nagui ST; Hall, Frances C; Ruddock, Sharon P; Fernandez, Catherine; Hulme, Claire T; Davies, Kevin A; Edwards, Christopher John; Lanyon, Peter C; Moots, Robert J; Roussou, Euthalia; Richards, Andrea; Sharples, Linda D; Bombardieri, Michele; Bowman, Simon J
  • Effect of individual patient risk, centre, surgeon and anaesthetist on length of stay in hospital after cardiac surgery: Association of Cardiothoracic Anaesthesia and Critical Care (ACTACC) consecutive cases series study of 10 UK specialist centres. (2017) Papachristofi, Olympia; Klein, Andrew A; Mackay, John; Nashef, Samer; Fletcher, Nick; Sharples, Linda D; Association of Cardiothoracic Anaesthesia and Critical Care (ACT
  • Erratum to: Using Parameter Constraints to Choose State Structures in Cost-Effectiveness Modelling. (2017) Thom, H; Jackson, C; Welton, N; Sharples, L
  • Using Parameter Constraints to Choose State Structures in Cost-Effectiveness Modelling. (2017) Thom, Howard; Jackson, Chris; Welton, Nicky; Sharples, Linda
  • Methods for Handling Unobserved Covariates in a Bayesian Update of a Cost-effectiveness Model. (2017) Thorpe, Benjamin; Carroll, Orlagh; Sharples, Linda
  • 2016
  • The relationship between three-dimensional knee MRI bone shape and total knee replacement-a case control study: data from the Osteoarthritis Initiative. (2016) Barr, Andrew J; Dube, Bright; Hensor, Elizabeth MA; Kingsbury, Sarah R; Peat, George; Bowes, Mike A; Sharples, Linda D; Conaghan, Philip G
  • Sex-related differences in left ventricular remodeling in severe aortic stenosis and reverse remodeling after aortic valve replacement: A cardiovascular magnetic resonance study. (2016) Dobson, Laura E; Fairbairn, Timothy A; Musa, Tarique A; Uddin, Akhlaque; Mundie, Cheryl A; Swoboda, Peter P; Ripley, David P; McDiarmid, Adam K; Erhayiem, Bara; Garg, Pankaj; Malkin, Christopher J; Blackman, Daniel J; Sharples, Linda D; Plein, Sven; Greenwood, John P
  • Use of a Structured Mirrors Intervention Does Not Reduce Delirium Incidence But May Improve Factual Memory Encoding in Cardiac Surgical ICU Patients Aged Over 70 Years: A Pilot Time-Cluster Randomized Controlled Trial. (2016) Giraud, Kimberly; Pontin, Megan; Sharples, Linda D; Fletcher, Paul; Dalgleish, Tim; Eden, Allaina; Jenkins, David P; Vuylsteke, Alain
  • Effect of Care Guided by Cardiovascular Magnetic Resonance, Myocardial Perfusion Scintigraphy, or NICE Guidelines on Subsequent Unnecessary Angiography Rates: The CE-MARC 2 Randomized Clinical Trial. (2016) Greenwood, John P; Ripley, David P; Berry, Colin; McCann, Gerry P; Plein, Sven; Bucciarelli-Ducci, Chiara; Dall'Armellina, Erica; Prasad, Abhiram; Bijsterveld, Petra; Foley, James R; Mangion, Kenneth; Sculpher, Mark; Walker, Simon; Everett, Colin C; Cairns, David A; Sharples, Linda D; Brown, Julia M; CE-MARC 2 Investigators
  • Extrapolating Survival from Randomized Trials Using External Data: A Review of Methods. (2016) Jackson, Christopher; Stevens, John; Ren, Shijie; Latimer, Nick; Bojke, Laura; Manca, Andrea; Sharples, Linda
  • Anaesthetist contribution to mortality after cardiac surgery - a reply. (2016) Mackay, JH; Nashef, SAM; Klein, AA; Papachristofi, O; Sharples, LD; Fletcher, SN; Association of Cardiothoracic Anaesthetists (ACTA)
  • Assessment of learning curves in complex surgical interventions: a consecutive case-series study. (2016) Papachristofi, Olympia; Jenkins, David; Sharples, Linda D
  • Evaluation of the effects of multiple providers in complex surgical interventions. (2016) Papachristofi, Olympia; Klein, Andrew; Sharples, Linda
  • 2015
  • Interventions in randomised controlled trials in surgery: issues to consider during trial design. (2015) Blencowe, Natalie S; Brown, Julia M; Cook, Jonathan A; Metcalfe, Chris; Morton, Dion G; Nicholl, Jon; Sharples, Linda D; Treweek, Shaun; Blazeby, Jane M; Members of the MRC Hub for Trials Methodology Research Network W
  • Bayesian regression discontinuity designs: incorporating clinical knowledge in the causal analysis of primary care data. (2015) Geneletti, Sara; O'Keeffe, Aidan G; Sharples, Linda D; Richardson, Sylvia; Baio, Gianluca
  • Multi-state modelling of repeated hospitalisation and death in patients with heart failure: The use of large administrative databases in clinical epidemiology. (2015) Ieva, Francesca; Jackson, Christopher H; Sharples, Linda D
  • An exploratory cohort study comparing prothrombin complex concentrate and fresh frozen plasma for the treatment of coagulopathy after complex cardiac surgery. (2015) Ortmann, Erik; Besser, Martin W; Sharples, Linda D; Gerrard, Caroline; Berman, Marius; Jenkins, David P; Klein, Andrew A
  • The contribution of the anaesthetist to risk-adjusted mortality after cardiac surgery. (2015) Papachristofi, O; Sharples, LD; Mackay, JH; Nashef, SAM; Fletcher, SN; Klein, AA; Association of Cardiothoracic Anaesthetists (ACTA)
  • The ETTAA study protocol: a UK-wide observational study of 'Effective Treatments for Thoracic Aortic Aneurysm'. (2015) Sastry, Priya; Hughes, Victoria; Hayes, Paul; Vallabhaneni, Srinivasa; Sharples, Linda; Thompson, Matt; Catarino, Pedro; Moorjani, Narain; Vale, Luke; Gray, Joanne; Cook, Andrew; Elefteriades, John A; Large, Stephen R; ETTAA Collaborators
  • Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea. (2015) Sharples, Linda D; Clutterbuck-James, Abigail L; Glover, Matthew J; Bennett, Maxine S; Chadwick, Rebecca; Pittman, Marcus A; Quinnell, Timothy G
  • Response to comments on "Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea". (2015) Sharples, Linda D; Quinnell, Timothy G; TOMADO investigators
  • State selection in Markov models for panel data with application to psoriatic arthritis. (2015) Thom, Howard HZ; Jackson, Christopher H; Commenges, Daniel; Sharples, Linda D
  • 2014
  • Survival extrapolation in the presence of cause specific hazards. (2014) Benaglia, Tatiana; Jackson, Christopher H; Sharples, Linda D
  • Contemporary roles of registries in clinical cardiology: when do we need randomized trials? (2014) Ieva, Francesca; Gale, Chris P; Sharples, Linda D
  • Impact of donor mismatches at individual HLA-A, -B, -C, -DR, and -DQ loci on the development of HLA-specific antibodies in patients listed for repeat renal transplantation. (2014) Kosmoliaptsis, Vasilios; Gjorgjimajkoska, Olivera; Sharples, Linda D; Chaudhry, Afzal N; Chatzizacharias, Nikolaos; Peacock, Sarah; Torpey, Nicholas; Bolton, Eleanor M; Taylor, Craig J; Bradley, J Andrew
  • The 'Switch' study protocol: a randomised-controlled trial of switching to an alternative tumour-necrosis factor (TNF)-inhibitor drug or abatacept or rituximab in patients with rheumatoid arthritis who have failed an initial TNF-inhibitor drug. (2014) Navarro Coy, Nuria C; Brown, Sarah; Bosworth, Ailsa; Davies, Claire T; Emery, Paul; Everett, Colin C; Fernandez, Catherine; Gray, Janine C; Hartley, Suzanne; Hulme, Claire; Keenan, Anne-Maree; McCabe, Christopher; Redmond, Anthony; Reynolds, Catherine; Scott, David; Sharples, Linda D; Pavitt, Sue; Buch, Maya H
  • Regression discontinuity designs: an approach to the evaluation of treatment efficacy in primary care using observational data. (2014) O'Keeffe, Aidan G; Geneletti, Sara; Baio, Gianluca; Sharples, Linda D; Nazareth, Irwin; Petersen, Irene
  • A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO). (2014) Quinnell, Timothy G; Bennett, Maxine; Jordan, Jake; Clutterbuck-James, Abigail L; Davies, Michael G; Smith, Ian E; Oscroft, Nicholas; Pittman, Marcus A; Cameron, Malcolm; Chadwick, Rebecca; Morrell, Mary J; Glover, Matthew J; Fox-Rushby, Julia A; Sharples, Linda D
  • Efficacy and cost of video-assisted thoracoscopic partial pleurectomy versus talc pleurodesis in patients with malignant pleural mesothelioma (MesoVATS): an open-label, randomised, controlled trial. (2014) Rintoul, Robert C; Ritchie, Andrew J; Edwards, John G; Waller, David A; Coonar, Aman S; Bennett, Maxine; Lovato, Eleonora; Hughes, Victoria; Fox-Rushby, Julia A; Sharples, Linda D; MesoVATS Collaborators
  • Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: mid-term outcomes from the CECaT randomised controlled trial. (2014) Thom, Howard; West, Nicholas EJ; Hughes, Vikki; Dyer, Matthew; Buxton, Martin; Sharples, Linda D; Jackson, Christopher H; Crean, Andrew M; CECaT study group
  • 2013
  • Calibration of complex models through Bayesian evidence synthesis: a demonstration and tutorial. (2013) Jackson, Christopher H; Jit, Mark; Sharples, Linda D; De Angelis, Daniela
  • Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective. (2013) Rintoul, Robert C; Glover, Matthew J; Jackson, Christopher; Hughes, Victoria; Tournoy, Kurt G; Dooms, Christophe; Annema, Jouke T; Sharples, Linda D
  • 2011
  • Survival extrapolation using the poly-Weibull model. (2011) Demiris, Nikolaos; Lunn, David; Sharples, Linda D
  • 2010
  • Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease. (2010) Goldsmith, Kimberley A; Dyer, Matthew T; Buxton, Martin J; Sharples, Linda D
  • Structural and parameter uncertainty in Bayesian cost-effectiveness models. (2010) Jackson, Christopher H; Sharples, Linda D; Thompson, Simon G
  • 2009
  • Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions. (2009) Goldsmith, Kimberley A; Dyer, Matthew T; Schofield, Peter M; Buxton, Martin J; Sharples, Linda D
  • Accounting for uncertainty in health economic decision models by using model averaging. (2009) Jackson, Christopher H; Thompson, Simon G; Sharples, Linda D
  • 2008
  • Clinical and cost-effectiveness analysis of an open label, single-centre, randomised trial of spinal cord stimulation (SCS) versus percutaneous myocardial laser revascularisation (PMR) in patients with refractory angina pectoris: The SPiRiT trial. (2008) Dyer, MT; Goldsmith, KA; Khan, SN; Sharples, LD; Freeman, C; Hardy, I; Buxton, MJ; Schofield, PM
  • A study to assess changes in myocardial perfusion after treatment with spinal cord stimulation and percutaneous myocardial laser revascularisation; data from a randomised trial. (2008) Khan, Sadia N; McNab, Duncan C; Sharples, Linda D; Freeman, Carol J; Hardy, Ian; Stone, David L; Schofield, Peter M
  • 2006
  • Comparison of shuttle walk with measured peak oxygen consumption in patients with operable lung cancer. (2006) Win, T; Jackson, A; Groves, AM; Sharples, LD; Charman, SC; Laroche, CM
  • 2005
  • Does heart transplantation confer survival benefit in all risk groups? (2005) Luckraz, Heyman; Sharples, Linda D; Charman, Susan C; Tsui, Steven SL; Wallwork, John; Parameshwar, Jayan; Large, Stephen R
  • Extended ganciclovir prophylaxis in lung transplantation. (2005) Perreas, KG; McNeil, K; Charman, S; Sharples, LD; Wreghitt, T; Wallwork, J
  • 2003
  • Performance status score: do patients and their oncologists agree? (2003) Blagden, SP; Charman, SC; Sharples, LD; Magee, LRA; Gilligan, D
  • 2002
  • Assessment of survival benefit after lung transplantation by patient diagnosis. (2002) Charman, Susan C; Sharples, Linda D; McNeil, Keith D; Wallwork, John
  • Swan-Ganz catheter assessment of donor hearts: outcome of organs with borderline hemodynamics. (2002) Stoica, Serban C; Satchithananda, Duwarakan K; Charman, Susan; Sharples, Linda; King, Robert; Rozario, Chris; Dunning, John; Tsui, Steven S; Wallwork, John; Large, Stephen R