Is the Expanded Programme on Immunisation the most appropriate delivery system for intermittent preventive treatment of malaria in West Africa?

Daniel Chandramohan ORCID logo; Jayne Webster ORCID logo; Lucy Smith; Timothy Awine; Seth Owusu-Agyei; Ilona Carneiro; (2007) Is the Expanded Programme on Immunisation the most appropriate delivery system for intermittent preventive treatment of malaria in West Africa? Tropical medicine & international health, 12 (6). pp. 743-750. ISSN 1360-2276 DOI: 10.1111/j.1365-3156.2007.01844.x
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OBJECTIVE: To investigate the coverage and equity of the Expanded Programme on Immunisation (EPI) and its effect on age schedule, seasonality of malaria risk, and linked intermittent preventive treatment (IPT) in West Africa. METHOD: Secondary analyses of data from a trial of IPT in Ghana. The potential effectiveness and impact of EPI-linked IPT in West Africa was calculated using the coverage of Diptheria Pertussis Tetanus vaccination obtained from national surveys and the reported protective efficacies of IPT. RESULTS: In West Africa, where the transmission of malaria is highly seasonal, only 10% of malaria episodes in infants would be averted with the current coverage of EPI. CONCLUSION: In this setting, the EPI-linked IPT is not necessarily the most appropriate approach and alternative IPT schedules and delivery systems are needed.
Item Type Article
Keywords expanded programme on immunisation, intermittent preventive treatment, malaria, seasonality, coverage, ghana, Placebo-controlled trial, insecticide-treated bednets, routine, vaccinations, measles vaccination, equitable coverage, tanzanian, infants, child-mortality, health, interventions, eradication, Africa, Western, epidemiology, Age Distribution, Child, Child, Preschool, Delivery of Health Care, methods, Humans, Immunization Programs, methods, Incidence, Infant, Malaria, epidemiology, prevention & control, Malaria Vaccines, therapeutic use, Mothers, psychology, Seasons, Treatment Outcome
ISI 247175000006

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