Pertussis vaccine effectiveness in reducing clinical disease, transmissibility and proportion of cases with a positive culture after household exposure in Brazil.
Paulo N Baptista;
Vera Magalhães;
Laura C Rodrigues;
MariaAngela W Rocha;
Analíria M Pimentel;
(2006)
Pertussis vaccine effectiveness in reducing clinical disease, transmissibility and proportion of cases with a positive culture after household exposure in Brazil.
The Pediatric infectious disease journal, 25 (9).
pp. 844-846.
ISSN 0891-3668
DOI: 10.1097/01.inf.0000232642.25495.95
In household outbreaks of pertussis, children <5 years of age who received at least 3 doses of vaccine had 12% less clinical disease; vaccinated cases were 63% less culture-confirmed and transmitted infection to 62% fewer contacts. Three doses of pertussis vaccine are likely to decrease circulation of Bordetella pertussis by reducing the proportion of bacteriologically positive cases and transmissibility.
| Item Type | Article |
|---|---|
| Keywords | Adolescent, Adult, Child, Child, Preschool, Disease Transmission, Horizontal/*prevention & control, Family Characteristics, Female, Humans, Infant, Infant, Newborn, Male, Pertussis Vaccine/*therapeutic use, Whooping Cough/*prevention & control/transmission, Adolescent, Adult, Child, Child, Preschool, Disease Transmission, Horizontal, prevention & control, Family Characteristics, Female, Humans, Infant, Infant, Newborn, Male, Pertussis Vaccine, therapeutic use, Whooping Cough, prevention & control, transmission |
| ISI | 240262200018 |