Preventing antiretroviral anarchy in sub-Saharan Africa.
AD Harries;
DS Nyangulu;
NJ Hargreaves;
O Kaluwa;
FM Salaniponi;
(2001)
Preventing antiretroviral anarchy in sub-Saharan Africa.
Lancet, 358 (9279).
pp. 410-414.
ISSN 0140-6736
DOI: 10.1016/s0140-6736(01)05551-9
Combination antiretroviral therapy has dramatically improved the survival of patients living with HIV and AIDS in industrialised countries of the world. Despite this enormous benefit, there are some major problems and obstacles to be overcome.(1) Treatment of HIV-infection is likely to be lifelong.(2) Unfortunately, many HIV-infected individuals cannot tolerate the toxic effects of the drugs, or have difficulty complying with treatment which involves large numbers of pills and complicated dosing schedules. Poor adherence to treatment leads to the emergence of drug-resistant viral strains that need new combinations of drugs or new drugs altogether.
| Item Type | Article |
|---|---|
| Keywords | Acquired Immunodeficiency Syndrome, Africa South of the Sahara, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Communicable Disease Control, Drug Resistance, Microbial, HIV Infections, Humans, Patient Compliance, Tuberculosis, Acquired Immunodeficiency Syndrome, drug therapy, epidemiology, Africa South of the Sahara, epidemiology, Anti-HIV Agents, economics, therapeutic use, Antiretroviral Therapy, Highly Active, economics, Communicable Disease Control, organization & administration, Drug Resistance, Microbial, HIV Infections, drug therapy, epidemiology, Humans, Patient Compliance, Tuberculosis, prevention & control |
| ISI | 170235100036 |