Vaccines against malaria - an update.
KaiMatuschewski;
Ann-KristinMueller;
(2007)
Vaccines against malaria - an update.
The FEBS journal, 274 (18).
pp. 4680-4687.
ISSN 1742-464X
DOI: 10.1111/j.1742-4658.2007.05998.x
Malaria vaccine discovery and development follow two principal strategies. Most subunit vaccines are designed to mimic naturally acquired immunity that develops over years upon continuous exposure to Plasmodium transmission. Experimental model vaccines, such as attenuated live parasites and transmission-blocking antigens, induce immune responses superior to naturally acquired immunity. The promises and hurdles of the different tracks towards an effective and affordable vaccine against malaria are discussed.
Item Type | Article |
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ISI | 249164800003 |
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