Meclonazepam analogues as potential new antihelmintic agents.

Aman Mahajan; Vipan Kumar; Nuha RN Mansour; Quentin Bickle; Kelly Chibale; (2008) Meclonazepam analogues as potential new antihelmintic agents. Bioorganic & medicinal chemistry letters, 18 (7). pp. 2333-2336. ISSN 0960-894X DOI: 10.1016/j.bmcl.2008.02.077
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New analogues of the potent antihelmintic meclonazepam were prepared and evaluated against Schistosoma mansoni. The biological data suggests substitution at positions 2 and 4 of meclonazepam could provide promising analogues for prophylactic and therapeutic activity against S. mansoni.
Item Type Article
Keywords meclonazepam, Schistosomiasis, SCHISTOSOMA-MANSONI, PRAZIQUANTEL, OXAMNIQUINE
ISI 255246300019

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