Pulmonary cryptococcosis misdiagnosed as smear-negative pulmonary tuberculosis with fatal consequences.
Joseph N Jarvis
;
Helen Wainwright;
Thomas S Harrison;
Kevin Rebe;
Graeme Meintjes;
(2010)
Pulmonary cryptococcosis misdiagnosed as smear-negative pulmonary tuberculosis with fatal consequences.
International journal of infectious diseases, 14 Sup (SUPPL.).
e310-e312.
ISSN 1201-9712
DOI: 10.1016/j.ijid.2010.02.2255
HIV-associated pulmonary cryptococcosis is under diagnosed, and may progress to fatal meningoencephalitis. We present a case of HIV-associated pulmonary Cryptococcus neoformans infection, initially mis-diagnosed as smear-negative pulmonary TB, which progressed to fatal cryptococcal meningitis. Autopsy series suggest that pulmonary cryptococcosis is common in African AIDS patients, and, due to limited diagnostic capacity, often mis-diagnosed as smear negative TB. Serum cryptococcal antigen testing may facilitate diagnosis in such cases.
Item Type | Article |
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ISI | 282643000072 |
ORCID: https://orcid.org/0000-0003-1459-5554