Antigenic variation: extending the reach of telomeric silencing.

David Horn; (2009) Antigenic variation: extending the reach of telomeric silencing. Current biology, 19 (12). R496-R498. ISSN 0960-9822 DOI: 10.1016/j.cub.2009.04.049
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Immune evasion in the parasitic African trypanosome relies upon the silencing of variant surface glycoprotein genes that are found adjacent to telomeres. Work on the RAP1 telomere-binding protein now indicates that silencing spreads over a sufficient distance to repress these genes.

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