Extensive transmission of Mycobacterium tuberculosis among children on a school bus.

Edmundo Neira-Munoz; Janette Smith; Paul Cockcroft; Damian Basher; Ibrahim Abubakar; (2008) Extensive transmission of Mycobacterium tuberculosis among children on a school bus. The Pediatric infectious disease journal, 27 (9). pp. 835-837. ISSN 0891-3668 DOI: 10.1097/INF.0b013e31816ff7c5
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We report a tuberculosis outbreak in school children caused by exposure to a sputum-smear positive school bus driver. Exposed children were assessed using 2 versions of interferon-gamma release assays. Fifty-five percent (18/34) had a positive interferon-gamma release assays and 4 children developed tuberculosis. This suggests that transmission may be very efficient in this setting and highlights the need for early diagnosis.

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