RETRACTED: Gradual emergence followed by exponential spread of the SARS-CoV-2 Omicron variant in Africa.
;
Tongai Gibson Maponga ;
Anges Yadouleton ;
NuroAbílio;
Emmanuel Aboce ;
PraiseAdewumi;
PedroAfonso;
Jewelna Akorli ;
Soa Fy Andriamandimby ;
LatifaAnga;
+78 more...
YvonneAshong;
Mohamed AmineBeloufa;
AichaBensalem;
RichardBirtles;
Anicet Luc MagloireBoumba;
FreddieBwanga;
Mike Chaponda ;
ParadzaiChibukira;
R Matthew Chico ;
Justin Chileshe ;
Gershom Chongwe ;
AssanaCissé;
Umberto D'Alessandro ;
Xavier Nicolas de Lamballerie ;
Joana FM de Morais ;
Fawzi Derrar ;
NdongoDia;
Youssouf Diarra ;
LassinaDoumbia;
Christian Drosten ;
Philippe Dussart ;
Richard Echodu ;
YannikEggers;
AbdelmajidEloualid;
Ousmane Faye ;
TorstenFeldt;
AnnaFrühauf;
AfiwaHalatoko;
Pauliana-Vanessa Ilouga ;
NaliaIsmael;
RonanJambou;
Sheikh Jarju ;
Antje Kamprad ;
BenKatowa;
JohnKayiwa;
Leonard King'wara ;
OusmaneKoita;
Vincent Lacoste ;
AdamouLagare;
Olfert Landt ;
Sonia Etenna Lekana-Douki ;
Jean-Bernard Lekana-Douki ;
EtuholeIipumbu;
Hugues Loemba ;
Julius Lutwama ;
SantouMamadou;
Issaka Maman ;
BrendonManyisa;
Pedro AMartinez;
Japhet Matoba ;
LusiaMhuulu;
AndresMoreira-Soto;
Judy Mwangi ;
NadineN Dilimabaka;
Charity AngellaNassuna;
Mamadou Ousmane Ndiath ;
EmmanuelNepolo;
RichardNjouom;
Jalal Nourlil ;
Steven GerNyanjom;
Eddy Okoth Odari ;
AlfredOkeng;
Jean BienvenueOuoba;
Michael Owusu ;
Irene Owusu Donkor ;
Karabo KristenPhadu;
Richard Odame Phillips ;
Wolfgang Preiser ;
VurayaiRuhanya;
FortuneSalah;
SourakatouSalifou;
Amadou AlphaSall;
Augustina Angelina Sylverken ;
Paul Alain Tagnouokam-Ngoupo ;
Zekiba Tarnagda ;
Francis OlivierTchikaya;
Tafese Beyene Tufa ;
Jan Felix Drexler ;
(2022)
RETRACTED: Gradual emergence followed by exponential spread of the SARS-CoV-2 Omicron variant in Africa.
Science (New York, N.Y.), 378 (6623).
eadd8737-.
ISSN 0036-8075
DOI: 10.1126/science.add8737
The geographic and evolutionary origins of the SARS-CoV-2 Omicron variant (BA.1), which was first detected mid-November 2021 in Southern Africa, remain unknown. We tested 13,097 COVID-19 patients sampled between mid-2021 to early 2022 from 22 African countries for BA.1 by real-time RT-PCR. By November-December 2021, BA.1 had replaced the Delta variant in all African sub-regions following a South-North gradient, with a peak Rt of 4.1. Polymerase chain reaction and near-full genome sequencing data revealed genetically diverse Omicron ancestors already existed across Africa by August 2021. Mutations, altering viral tropism, replication and immune escape, gradually accumulated in the spike gene. Omicron ancestors were therefore present in several African countries months before Omicron dominated transmission. These data also indicate that travel bans are ineffective in the face of undetected and widespread infection.
-
picture_as_pdf - Fischer-etal_2022_Gradual-emergence-followed-by-exponential.pdf
-
subject - Published Version
-
- Available under Creative Commons: 4.0
Explore Further
Read more research from the creator(s):
Find work associated with the faculties and division(s):
Find work from this publication: