Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries.

Erin Rottinghaus Romano; Katrina Sleeman; Patricia Hall-Eidson; Clement Zeh; Ravikiran Bhairavabhotla; Guoqing Zhang; Amitabh Adhikari; George Alemnji; Yolanda Rebello Cardo; Ana Pinheiro; +45 more... Barbara Pocongo; Laura T Eno; Judith D Shang; Clement B Ndongmo; Hilda Rosario; Orquidea Moreno; Lucia Aurora De La Cruz De León; Peter Fonjungo; Constantin Kabwe; Steve Ahuke-Mundeke; Dan Gama; Sindisiwe Dlamini; Gugu Maphalala; Tefsay Abreha; Anne Purfield; Yared Tedla Gebrehiwot; Daniel Melese Desalegn; Frank Basiye; Jane Mwangi; Nancy Bowen; Yohannes Mengistu; Shirley Lecher; Elizabeth Kampira; Muluken Kaba; Joseph Bitilinyu-Bangoh; Gillian Masamha; Sofia Omar Viegas; R Suzanne Beard; Gerhard van Rooyen; Andreas N Shiningavamwe; McPaul I J; Nnaemeka C Iriemenam; Nwando Mba; Catherine Okoi; Joel Katoro; Dennis L Kenyi; Bior K Bior; Christina Mwangi; Susan Nabadda; Pontiano Kaleebu ORCID logo; Samuel L Yingst; Prisca Chikwanda; Levi Veri; Raivi Simbi; Heather Alexander; (2022) Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries. Emerging infectious diseases, 28 (13). S59-S68. ISSN 1080-6040 DOI: 10.3201/eid2813.220789
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The US President's Emergency Plan for AIDS Relief (PEPFAR) supports molecular HIV and tuberculosis diagnostic networks and information management systems in low- and middle-income countries. We describe how national programs leveraged these PEPFAR-supported laboratory resources for SARS-CoV-2 testing during the COVID-19 pandemic. We sent a spreadsheet template consisting of 46 indicators for assessing the use of PEPFAR-supported diagnostic networks for COVID-19 pandemic response activities during April 1, 2020, to March 31, 2021, to 27 PEPFAR-supported countries or regions. A total of 109 PEPFAR-supported centralized HIV viral load and early infant diagnosis laboratories and 138 decentralized HIV and TB sites reported performing SARS-CoV-2 testing in 16 countries. Together, these sites contributed to >3.4 million SARS-CoV-2 tests during the 1-year period. Our findings illustrate that PEPFAR-supported diagnostic networks provided a wide range of resources to respond to emergency COVID-19 diagnostic testing in 16 low- and middle-income countries.


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